IMP
Process View
gpi anchor biosynthetic process
The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "gpi anchor biosynthetic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| 5730494N06Rik | RIKEN cDNA 5730494N06 gene | 0.113 | ||
| Immp1l | IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.106 | ||
| 1810030N24Rik | RIKEN cDNA 1810030N24 gene | 0.105 | ||
| Atp5s | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s | 0.089 | ||
| Fnta | farnesyltransferase, CAAX box, alpha | 0.051 | ||
| Tcap | titin-cap | 0.030 | ||
| Vti1b | vesicle transport through interaction with t-SNAREs 1B homolog | 0.027 | ||
| 1110058L19Rik | RIKEN cDNA 1110058L19 gene | 0.026 | ||
| Slc25a39 | solute carrier family 25, member 39 | 0.025 | ||
| Pdcd2 | programmed cell death 2 | 0.025 | ||
| Ptpn2 | protein tyrosine phosphatase, non-receptor type 2 | 0.024 | ||
| Med31 | mediator of RNA polymerase II transcription, subunit 31 homolog (yeast) | 0.021 | ||
| Acyp1 | acylphosphatase 1, erythrocyte (common) type | 0.020 | ||
| Ube2t | ubiquitin-conjugating enzyme E2T (putative) | 0.018 | ||
| Tmem218 | transmembrane protein 218 | 0.018 | ||
| 0610009B22Rik | RIKEN cDNA 0610009B22 gene | 0.018 | ||
| Pgam2 | phosphoglycerate mutase 2 | 0.017 | ||
| Pigo | phosphatidylinositol glycan anchor biosynthesis, class O | 0.017 | ||
| Trim54 | tripartite motif-containing 54 | 0.015 | ||
| Tab3 | TGF-beta activated kinase 1/MAP3K7 binding protein 3 | 0.015 | ||
| Polr2k | polymerase (RNA) II (DNA directed) polypeptide K | 0.015 | ||
| Ccdc90b | coiled-coil domain containing 90B | 0.015 | ||
| Eef1a2 | eukaryotic translation elongation factor 1 alpha 2 | 0.015 | ||
| Rbm15 | RNA binding motif protein 15 | 0.014 | ||
| Polr3k | polymerase (RNA) III (DNA directed) polypeptide K | 0.014 | ||
| Tprgl | transformation related protein 63 regulated like | 0.013 | ||
| Bnip3 | BCL2/adenovirus E1B interacting protein 3 | 0.013 | ||
| Rab28 | RAB28, member RAS oncogene family | 0.013 | ||
| Rnf7 | ring finger protein 7 | 0.013 | ||
| Cetn2 | centrin 2 | 0.012 | ||
| Pvalb | parvalbumin | 0.012 | ||
| Pex3 | peroxisomal biogenesis factor 3 | 0.012 | ||
| Unc50 | unc-50 homolog (C. elegans) | 0.011 | ||
| Tmem128 | transmembrane protein 128 | 0.011 | ||
| 1110005A03Rik | RIKEN cDNA 1110005A03 gene | 0.011 | ||
| Isca1 | iron-sulfur cluster assembly 1 homolog (S. cerevisiae) | 0.011 | ||
| Caml | calcium modulating ligand | 0.011 | ||
| Brp44 | brain protein 44 | 0.011 | ||
| 1500031L02Rik | RIKEN cDNA 1500031L02 gene | 0.011 | ||
| Paip2 | polyadenylate-binding protein-interacting protein 2 | 0.010 | ||
| Atad3a | ATPase family, AAA domain containing 3A | 0.010 | ||
| Spcs1 | signal peptidase complex subunit 1 homolog (S. cerevisiae) | 0.010 | ||
| H47 | histocompatibility 47 | 0.010 | ||
| Fam134b | family with sequence similarity 134, member B | 0.010 |