IMP: Integrative Multi-species Prediction

Mus musculus

71 genes annotated in mouse

Multi-species View

negative regulation of hydrolase activity

GO:0051346

Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of hydrolase activity"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "negative regulation of hydrolase activity" (in gray)

Name	Description	Probability	Func Analog Organism
Tnf	tumor necrosis factor	0.974
Apoa1	apolipoprotein A-I	0.897
Serpina1c	serine (or cysteine) peptidase inhibitor, clade A, member 1C	0.808	Human Mouse Rat
Vegfa	vascular endothelial growth factor A	0.796	Human
Drd2	dopamine receptor D2	0.769
Il10	interleukin 10	0.768	Mouse
Ret	ret proto-oncogene	0.764
Lepr	leptin receptor	0.756
Mndal	myeloid nuclear differentiation antigen like	0.726
Fgg	fibrinogen gamma chain	0.721	Mouse
Ctla2a	cytotoxic T lymphocyte-associated protein 2 alpha	0.716	Fly
Cxcl13	chemokine (C-X-C motif) ligand 13	0.692
Dab1	disabled homolog 1 (Drosophila)	0.666
Vdr	vitamin D receptor	0.638
Sfrp1	secreted frizzled-related protein 1	0.637	Mouse
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.607
Arrb2	arrestin, beta 2	0.604	Mouse
Ctla2b	cytotoxic T lymphocyte-associated protein 2 beta	0.600	Fly
Hspa1a	heat shock protein 1A	0.592
Ptgs2	prostaglandin-endoperoxide synthase 2	0.591
Plg	plasminogen	0.575
Fga	fibrinogen alpha chain	0.552
Thbs2	thrombospondin 2	0.537
Ahsg	alpha-2-HS-glycoprotein	0.453	Mouse
Fgb	fibrinogen beta chain	0.438
Ifng	interferon gamma	0.436
Tlr4	toll-like receptor 4	0.431
Spry2	sprouty homolog 2 (Drosophila)	0.426
Arrb1	arrestin, beta 1	0.418
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.415
Osmr	oncostatin M receptor	0.385
Apoe	apolipoprotein E	0.382	Mouse
Axl	AXL receptor tyrosine kinase	0.381
Itih4	inter alpha-trypsin inhibitor, heavy chain 4	0.358
Nos1	nitric oxide synthase 1, neuronal	0.358
Gdnf	glial cell line derived neurotrophic factor	0.357
Il1r1	interleukin 1 receptor, type I	0.356
Vhl	von Hippel-Lindau tumor suppressor	0.356
Igh	immunoglobulin heavy chain complex	0.353
Ambp	alpha 1 microglobulin/bikunin	0.349	Rat
Ccl7	chemokine (C-C motif) ligand 7	0.346
Prkce	protein kinase C, epsilon	0.345
Lama5	laminin, alpha 5	0.340
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.333	Mouse
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.333
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.333
Agxt	alanine-glyoxylate aminotransferase	0.332
Spry4	sprouty homolog 4 (Drosophila)	0.326	Mouse
Sfrp2	secreted frizzled-related protein 2	0.322
Cfi	complement component factor i	0.321
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.318
Fgfr1	fibroblast growth factor receptor 1	0.316
Igf1	insulin-like growth factor 1	0.315	Rat
Egfr	epidermal growth factor receptor	0.313
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.311
Nf1	neurofibromatosis 1	0.309
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.303
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.297	Mouse
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.294
Apom	apolipoprotein M	0.286
Ifi203	interferon activated gene 203	0.284	Mouse
Foxc1	forkhead box C1	0.282
Ltb	lymphotoxin B	0.277
Serping1	serine (or cysteine) peptidase inhibitor, clade G, member 1	0.274
Gsk3b	glycogen synthase kinase 3 beta	0.273
Krt5	keratin 5	0.268
Mnda	myeloid cell nuclear differentiation antigen	0.263	Human Mouse
Plcg2	phospholipase C, gamma 2	0.258
Ccl2	chemokine (C-C motif) ligand 2	0.257
Il6	interleukin 6	0.253
Tgfa	transforming growth factor alpha	0.252
Apoc4	apolipoprotein C-IV	0.252
Msln	mesothelin	0.249
Lyz2	lysozyme 2	0.248
F2	coagulation factor II	0.247
Rarb	retinoic acid receptor, beta	0.246
Akr1c6	aldo-keto reductase family 1, member C6	0.242
Dnm1	dynamin 1	0.239
Serpind1	serine (or cysteine) peptidase inhibitor, clade D, member 1	0.238	Fly
Lhx1	LIM homeobox protein 1	0.233
Esr1	estrogen receptor 1 (alpha)	0.228
F9	coagulation factor IX	0.227
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.224
Ctsk	cathepsin K	0.222
Slc27a5	solute carrier family 27 (fatty acid transporter), member 5	0.222
Fas	Fas (TNF receptor superfamily member 6)	0.221
Alb	albumin	0.221
Htra3	HtrA serine peptidase 3	0.220
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.216	Mouse
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.214
Dusp1	dual specificity phosphatase 1	0.208
Lif	leukemia inhibitory factor	0.205
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.204
C1ra	complement component 1, r subcomponent A	0.203
Hpx	hemopexin	0.203
Emx2	empty spiracles homolog 2 (Drosophila)	0.202
Apob	apolipoprotein B	0.201
Serpina3m	serine (or cysteine) peptidase inhibitor, clade A, member 3M	0.197	Mouse
Nrp1	neuropilin 1	0.193
Wnt3a	wingless-related MMTV integration site 3A	0.193	Mouse
Casp1	caspase 1	0.192
Pou3f1	POU domain, class 3, transcription factor 1	0.189
Apcs	serum amyloid P-component	0.188	Human
Casp12	caspase 12	0.188
Fosl2	fos-like antigen 2	0.187
Emx1	empty spiracles homolog 1 (Drosophila)	0.181
Gja1	gap junction protein, alpha 1	0.181
Fos	FBJ osteosarcoma oncogene	0.179
Cd40	CD40 antigen	0.179
Tinagl1	tubulointerstitial nephritis antigen-like 1	0.179
Inpp5d	inositol polyphosphate-5-phosphatase D	0.177
Aldob	aldolase B, fructose-bisphosphate	0.176
Ngf	nerve growth factor	0.175
Cxcr5	chemokine (C-X-C motif) receptor 5	0.175
Hnf4a	hepatic nuclear factor 4, alpha	0.175
Chd7	chromodomain helicase DNA binding protein 7	0.173
Dcn	decorin	0.173
Irs2	insulin receptor substrate 2	0.172
Aicda	activation-induced cytidine deaminase	0.169
Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	0.168	Mouse
Spry1	sprouty homolog 1 (Drosophila)	0.168
Prnp	prion protein	0.168
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.167
Lmna	lamin A	0.166
Dlg1	discs, large homolog 1 (Drosophila)	0.165
Myd88	myeloid differentiation primary response gene 88	0.165
Lum	lumican	0.162
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.157
Cyr61	cysteine rich protein 61	0.157
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.157
Ptk2	PTK2 protein tyrosine kinase 2	0.157
Fabp1	fatty acid binding protein 1, liver	0.156	Human
Pax3	paired box gene 3	0.155
Grb10	growth factor receptor bound protein 10	0.154
Krt14	keratin 14	0.153
Pax2	paired box gene 2	0.152	Human
Btk	Bruton agammaglobulinemia tyrosine kinase	0.151
En1	engrailed 1	0.150
Pmp22	peripheral myelin protein 22	0.149
Nbl1	neuroblastoma, suppression of tumorigenicity 1	0.149
Cnn1	calponin 1	0.148
Zeb1	zinc finger E-box binding homeobox 1	0.148
Cfh	complement component factor h	0.146
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.145
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.145
Cd151	CD151 antigen	0.142
Kng1	kininogen 1	0.141	Human
Pxn	paxillin	0.141
Ednra	endothelin receptor type A	0.141
AI607873	expressed sequence AI607873	0.139	Mouse
Epas1	endothelial PAS domain protein 1	0.139
Gc	group specific component	0.139
Ccl8	chemokine (C-C motif) ligand 8	0.139
Efnb2	ephrin B2	0.138
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.138
Ece1	endothelin converting enzyme 1	0.137
L1cam	L1 cell adhesion molecule	0.137
Akt1	thymoma viral proto-oncogene 1	0.136
Fxyd1	FXYD domain-containing ion transport regulator 1	0.135
Apoa2	apolipoprotein A-II	0.135
Hspa1b	heat shock protein 1B	0.134
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.134
Ephb3	Eph receptor B3	0.132
Trim30a	tripartite motif-containing 30A	0.132
Pzp	pregnancy zone protein	0.131
Map3k3	mitogen-activated protein kinase kinase kinase 3	0.130
Rab6	RAB6, member RAS oncogene family	0.129
Cp	ceruloplasmin	0.127
Ldb3	LIM domain binding 3	0.126
Sfrp4	secreted frizzled-related protein 4	0.125
Serpina1b	serine (or cysteine) preptidase inhibitor, clade A, member 1B	0.124
Postn	periostin, osteoblast specific factor	0.123
A2m	alpha-2-macroglobulin	0.122	Human Rat
Prkcc	protein kinase C, gamma	0.121	Mouse
Mmp9	matrix metallopeptidase 9	0.120
C4b	complement component 4B (Childo blood group)	0.118	Mouse
Otx1	orthodenticle homolog 1 (Drosophila)	0.117
Mgp	matrix Gla protein	0.117
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.116
Pstpip1	proline-serine-threonine phosphatase-interacting protein 1	0.115
Ifih1	interferon induced with helicase C domain 1	0.115
Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.114
Axin1	axin 1	0.114
Mup3	major urinary protein 3	0.114
Grin2a	glutamate receptor, ionotropic, NMDA2A (epsilon 1)	0.114
Lyve1	lymphatic vessel endothelial hyaluronan receptor 1	0.113
Rnf41	ring finger protein 41	0.112
Dlg4	discs, large homolog 4 (Drosophila)	0.112
Il7	interleukin 7	0.111
Men1	multiple endocrine neoplasia 1	0.111
Timp2	tissue inhibitor of metalloproteinase 2	0.111
Hspb8	heat shock protein 8	0.110	Mouse
Cdk4	cyclin-dependent kinase 4	0.109
Itih3	inter-alpha trypsin inhibitor, heavy chain 3	0.108
Aebp1	AE binding protein 1	0.108
Cxcl2	chemokine (C-X-C motif) ligand 2	0.107
Igfbp2	insulin-like growth factor binding protein 2	0.106
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.106
Srsf9	serine/arginine-rich splicing factor 9	0.106
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.105
Tmprss11e	transmembrane protease, serine 11e	0.104
Traf2	TNF receptor-associated factor 2	0.104
Crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.104
Tcf7	transcription factor 7, T-cell specific	0.103
Serpinb5	serine (or cysteine) peptidase inhibitor, clade B, member 5	0.103	Mouse
Il6st	interleukin 6 signal transducer	0.103
Gsn	gelsolin	0.102	Mouse
Pthlh	parathyroid hormone-like peptide	0.102
C2	complement component 2 (within H-2S)	0.101
Lrp6	low density lipoprotein receptor-related protein 6	0.101
Cd28	CD28 antigen	0.100
Gjb4	gap junction protein, beta 4	0.100
Slurp1	secreted Ly6/Plaur domain containing 1	0.100
Tox	thymocyte selection-associated high mobility group box	0.099
Ppp1r9b	protein phosphatase 1, regulatory subunit 9B	0.099
Adra2a	adrenergic receptor, alpha 2a	0.098
Il22	interleukin 22	0.098	Mouse
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.097
Cdt1	chromatin licensing and DNA replication factor 1	0.097
Plxna1	plexin A1	0.097
Tnks1bp1	tankyrase 1 binding protein 1	0.096
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.096
Fxyd3	FXYD domain-containing ion transport regulator 3	0.096
Il1a	interleukin 1 alpha	0.096
Smo	smoothened homolog (Drosophila)	0.096
Smad3	MAD homolog 3 (Drosophila)	0.095
Ces1c	carboxylesterase 1C	0.095
Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.094
H2-Q10	histocompatibility 2, Q region locus 10	0.094
Ddx6	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6	0.094
Ccr1	chemokine (C-C motif) receptor 1	0.094
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.094
Ereg	epiregulin	0.094
Fgf8	fibroblast growth factor 8	0.093
Nos3	nitric oxide synthase 3, endothelial cell	0.093
Igf1r	insulin-like growth factor I receptor	0.093	Zebrafish
Kcna6	potassium voltage-gated channel, shaker-related, subfamily, member 6	0.093
Plcg1	phospholipase C, gamma 1	0.093
C9	complement component 9	0.092
Cish	cytokine inducible SH2-containing protein	0.092
Skil	SKI-like	0.091
Apoc2	apolipoprotein C-II	0.090
Rnase4	ribonuclease, RNase A family 4	0.090
Nlrp3	NLR family, pyrin domain containing 3	0.089
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.089
Otx2	orthodenticle homolog 2 (Drosophila)	0.089
Camk2d	calcium/calmodulin-dependent protein kinase II, delta	0.089
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.089
E2f1	E2F transcription factor 1	0.088
Serpina12	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12	0.088	Mouse
Cyp2d10	cytochrome P450, family 2, subfamily d, polypeptide 10	0.088
Jarid2	jumonji, AT rich interactive domain 2	0.087
Vsig4	V-set and immunoglobulin domain containing 4	0.087
Sh3bp1	SH3-domain binding protein 1	0.087
Numb	numb gene homolog (Drosophila)	0.087
Wls	wntless homolog (Drosophila)	0.086
S100a6	S100 calcium binding protein A6 (calcyclin)	0.086
Lamc2	laminin, gamma 2	0.085
Lta	lymphotoxin A	0.085	Mouse
Rarg	retinoic acid receptor, gamma	0.085
Ednrb	endothelin receptor type B	0.084
Nphs2	nephrosis 2 homolog, podocin (human)	0.084
Ache	acetylcholinesterase	0.084
Igfbp1	insulin-like growth factor binding protein 1	0.084
Mx1	myxovirus (influenza virus) resistance 1	0.084
Morf4l1	mortality factor 4 like 1	0.084
Jak2	Janus kinase 2	0.084
Pla2g4a	phospholipase A2, group IVA (cytosolic, calcium-dependent)	0.084
Csn1s1	casein alpha s1	0.083
Rock2	Rho-associated coiled-coil containing protein kinase 2	0.082
Twf2	twinfilin, actin-binding protein, homolog 2 (Drosophila)	0.082
Cav1	caveolin 1, caveolae protein	0.082
Rb1	retinoblastoma 1	0.080
Birc3	baculoviral IAP repeat-containing 3	0.079	Mouse
Prkcb	protein kinase C, beta	0.079
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.078
Apoc1	apolipoprotein C-I	0.078
Flnc	filamin C, gamma	0.078
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.078
Rock1	Rho-associated coiled-coil containing protein kinase 1	0.077
Lamc1	laminin, gamma 1	0.077
Timp1	tissue inhibitor of metalloproteinase 1	0.076	Human Mouse Fly
Gbp1	guanylate binding protein 1	0.076
Ranbp1	RAN binding protein 1	0.076
Gpx3	glutathione peroxidase 3	0.076
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.075
Tpm2	tropomyosin 2, beta	0.075
Pyhin1	pyrin and HIN domain family, member 1	0.075	Mouse
Ctgf	connective tissue growth factor	0.075
Spp1	secreted phosphoprotein 1	0.075
Ifngr1	interferon gamma receptor 1	0.074
Tlr2	toll-like receptor 2	0.074
Ldlr	low density lipoprotein receptor	0.074
Trp53	transformation related protein 53	0.074
Gpr87	G protein-coupled receptor 87	0.074
Aplp1	amyloid beta (A4) precursor-like protein 1	0.073
Angptl3	angiopoietin-like 3	0.073
Itgb4	integrin beta 4	0.073
Gdf10	growth differentiation factor 10	0.073
Muc5ac	mucin 5, subtypes A and C, tracheobronchial/gastric	0.073
Arc	activity regulated cytoskeletal-associated protein	0.072
Onecut1	one cut domain, family member 1	0.072
Npc1	Niemann Pick type C1	0.072
Pkp1	plakophilin 1	0.072
Syt7	synaptotagmin VII	0.072
Lrp1	low density lipoprotein receptor-related protein 1	0.072
Tdo2	tryptophan 2,3-dioxygenase	0.071
Mbl2	mannose-binding lectin (protein C) 2	0.071
Apof	apolipoprotein F	0.071
Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	0.070
Cyp11b1	cytochrome P450, family 11, subfamily b, polypeptide 1	0.070
Vangl2	vang-like 2 (van gogh, Drosophila)	0.070
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.070
Ptplad2	protein tyrosine phosphatase-like A domain containing 2	0.070
Samhd1	SAM domain and HD domain, 1	0.070
Ly6a	lymphocyte antigen 6 complex, locus A	0.070
Ifi47	interferon gamma inducible protein 47	0.070
Dkk3	dickkopf homolog 3 (Xenopus laevis)	0.070
Arhgef7	Rho guanine nucleotide exchange factor (GEF7)	0.069
Cenpj	centromere protein J	0.069
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.069
Hamp	hepcidin antimicrobial peptide	0.068
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.068
Wnt7a	wingless-related MMTV integration site 7A	0.068	Mouse
Hoxd11	homeobox D11	0.068
Grk6	G protein-coupled receptor kinase 6	0.067
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.067
Crb1	crumbs homolog 1 (Drosophila)	0.067
Pdpk1	3-phosphoinositide dependent protein kinase 1	0.067
Dsg1a	desmoglein 1 alpha	0.067
Tgfbi	transforming growth factor, beta induced	0.067
Wnt5a	wingless-related MMTV integration site 5A	0.066	Mouse
Nradd	neurotrophin receptor associated death domain	0.066
Ccdc80	coiled-coil domain containing 80	0.066
Acvr1	activin A receptor, type 1	0.066
Itih1	inter-alpha trypsin inhibitor, heavy chain 1	0.065
Pdlim3	PDZ and LIM domain 3	0.065
Cd86	CD86 antigen	0.065
Diablo	diablo homolog (Drosophila)	0.065
Bag3	BCL2-associated athanogene 3	0.065	Mouse
Wasf2	WAS protein family, member 2	0.065
Apoa5	apolipoprotein A-V	0.064	Mouse
Thoc4	THO complex 4	0.063	Yeast
Kif5b	kinesin family member 5B	0.063
Ctnna2	catenin (cadherin associated protein), alpha 2	0.063
Serpina1e	serine (or cysteine) peptidase inhibitor, clade A, member 1E	0.063	Human Mouse Rat
Itgb3	integrin beta 3	0.062
Anxa1	annexin A1	0.062
Rgs16	regulator of G-protein signaling 16	0.062	Mouse
Epha4	Eph receptor A4	0.062
Capn2	calpain 2	0.062
Braf	Braf transforming gene	0.062
Serinc3	serine incorporator 3	0.062
Oprm1	opioid receptor, mu 1	0.062
Trim62	tripartite motif-containing 62	0.061
Igf2r	insulin-like growth factor 2 receptor	0.061
Mt4	metallothionein 4	0.061
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.061
F13a1	coagulation factor XIII, A1 subunit	0.061
Aldh1a3	aldehyde dehydrogenase family 1, subfamily A3	0.061
Tnfsf13b	tumor necrosis factor (ligand) superfamily, member 13b	0.061
Cpd	carboxypeptidase D	0.060
Ptprn	protein tyrosine phosphatase, receptor type, N	0.060
Clstn1	calsyntenin 1	0.060
Gnat1	guanine nucleotide binding protein, alpha transducing 1	0.060
Mcm3	minichromosome maintenance deficient 3 (S. cerevisiae)	0.059
Igf2	insulin-like growth factor 2	0.059
Serpina1a	serine (or cysteine) peptidase inhibitor, clade A, member 1A	0.059	Human Mouse Rat
Foxa2	forkhead box A2	0.059
Ifi204	interferon activated gene 204	0.059	Human Mouse
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.059
Hif1a	hypoxia inducible factor 1, alpha subunit	0.059
F10	coagulation factor X	0.058
Pcsk6	proprotein convertase subtilisin/kexin type 6	0.058
Mug1	murinoglobulin 1	0.058	Mouse
Nkx3-1	NK-3 transcription factor, locus 1 (Drosophila)	0.058
Egr1	early growth response 1	0.058
Ptpn12	protein tyrosine phosphatase, non-receptor type 12	0.058
Uox	urate oxidase	0.058
Rgn	regucalcin	0.058
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.058
Pah	phenylalanine hydroxylase	0.058
Pgam2	phosphoglycerate mutase 2	0.058
Ptprc	protein tyrosine phosphatase, receptor type, C	0.058
Rdh7	retinol dehydrogenase 7	0.058
Krt13	keratin 13	0.058
Shkbp1	Sh3kbp1 binding protein 1	0.057
Svep1	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1	0.057
Rhoj	ras homolog gene family, member J	0.057
Gm4788	predicted gene 4788	0.057
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.056
Prf1	perforin 1 (pore forming protein)	0.056
Sfrp5	secreted frizzled-related sequence protein 5	0.056	Mouse
Cps1	carbamoyl-phosphate synthetase 1	0.056
Plat	plasminogen activator, tissue	0.055
Mfap5	microfibrillar associated protein 5	0.055
Plxnd1	plexin D1	0.055
Timp3	tissue inhibitor of metalloproteinase 3	0.055	Mouse Fly
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.055
Serpinb6b	serine (or cysteine) peptidase inhibitor, clade B, member 6b	0.055	Human Mouse
Sprr2a2	small proline-rich protein 2A2	0.055
Igfbp6	insulin-like growth factor binding protein 6	0.055
Pdpn	podoplanin	0.055
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.055
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.054
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.054
Mal	myelin and lymphocyte protein, T-cell differentiation protein	0.054
Krtdap	keratinocyte differentiation associated protein	0.054
Ptpru	protein tyrosine phosphatase, receptor type, U	0.054
Axin2	axin2	0.054
Ttr	transthyretin	0.053
Crct1	cysteine-rich C-terminal 1	0.053
Celsr1	cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)	0.053
Hbegf	heparin-binding EGF-like growth factor	0.053
Serpinf2	serine (or cysteine) peptidase inhibitor, clade F, member 2	0.053	Human Mouse Rat
Gpc3	glypican 3	0.053
Sh3rf1	SH3 domain containing ring finger 1	0.053	Human
Stac	src homology three (SH3) and cysteine rich domain	0.053
Azgp1	alpha-2-glycoprotein 1, zinc	0.053
Shh	sonic hedgehog	0.053
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.053
Cnga2	cyclic nucleotide gated channel alpha 2	0.052
Ccdc109b	coiled-coil domain containing 109B	0.052
Hoxb9	homeobox B9	0.052
Dab2	disabled homolog 2 (Drosophila)	0.052
Bcl2	B-cell leukemia/lymphoma 2	0.052	Zebrafish
Gm10393	predicted gene 10393	0.052
Ric8	resistance to inhibitors of cholinesterase 8 homolog (C. elegans)	0.052
Akap9	A kinase (PRKA) anchor protein (yotiao) 9	0.052
Foxi3	forkhead box I3	0.052
P4ha1	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide	0.052
Mll5	myeloid/lymphoid or mixed-lineage leukemia 5	0.052
Sh3bgrl3	SH3 domain binding glutamic acid-rich protein-like 3	0.052
Stim2	stromal interaction molecule 2	0.052
Ifi44	interferon-induced protein 44	0.052
Rasl11b	RAS-like, family 11, member B	0.052
Fgf18	fibroblast growth factor 18	0.051
Otc	ornithine transcarbamylase	0.051
Ifit3	interferon-induced protein with tetratricopeptide repeats 3	0.051
Yap1	yes-associated protein 1	0.051
Fjx1	four jointed box 1 (Drosophila)	0.051
Apoh	apolipoprotein H	0.051
Prkar2b	protein kinase, cAMP dependent regulatory, type II beta	0.051
Rarres2	retinoic acid receptor responder (tazarotene induced) 2	0.051
Fgf15	fibroblast growth factor 15	0.051
Apod	apolipoprotein D	0.051
Crem	cAMP responsive element modulator	0.051
Crp	C-reactive protein, pentraxin-related	0.051
Cnr1	cannabinoid receptor 1 (brain)	0.051
Plec	plectin	0.051
Hspb7	heat shock protein family, member 7 (cardiovascular)	0.051
Hivep2	human immunodeficiency virus type I enhancer binding protein 2	0.051
Masp1	mannan-binding lectin serine peptidase 1	0.051
Cd19	CD19 antigen	0.051
Fgfr2	fibroblast growth factor receptor 2	0.051
Wt1	Wilms tumor 1 homolog	0.051
Anxa5	annexin A5	0.051
F12	coagulation factor XII (Hageman factor)	0.051
Msx2	homeobox, msh-like 2	0.050
AI413582	expressed sequence AI413582	0.050
Suz12	suppressor of zeste 12 homolog (Drosophila)	0.050
Blnk	B-cell linker	0.050
S100a14	S100 calcium binding protein A14	0.050
Mall	mal, T-cell differentiation protein-like	0.050
Iigp1	interferon inducible GTPase 1	0.050
Fam83g	family with sequence similarity 83, member G	0.050
Fzd1	frizzled homolog 1 (Drosophila)	0.050
Tiparp	TCDD-inducible poly(ADP-ribose) polymerase	0.050
Capzb	capping protein (actin filament) muscle Z-line, beta	0.050
Pdgfb	platelet derived growth factor, B polypeptide	0.050
G6pc	glucose-6-phosphatase, catalytic	0.050
Flna	filamin, alpha	0.050
Arg1	arginase, liver	0.049
Ilk	integrin linked kinase	0.049
Spock1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1	0.049	Human
Mybph	myosin binding protein H	0.049
Myc	myelocytomatosis oncogene	0.049
Hal	histidine ammonia lyase	0.049
Gvin1	GTPase, very large interferon inducible 1	0.049
Ets2	E26 avian leukemia oncogene 2, 3' domain	0.049
Prlr	prolactin receptor	0.049
Irx4	Iroquois related homeobox 4 (Drosophila)	0.049
Dnm1l	dynamin 1-like	0.049
Fzd6	frizzled homolog 6 (Drosophila)	0.049
Ms4a6b	membrane-spanning 4-domains, subfamily A, member 6B	0.049
BC100530	cDNA sequence BC100530	0.049	Human Mouse
Bcl6	B-cell leukemia/lymphoma 6	0.048
Mkl2	MKL/myocardin-like 2	0.048	Mouse
Tnfrsf8	tumor necrosis factor receptor superfamily, member 8	0.048
Angptl4	angiopoietin-like 4	0.048
Ghr	growth hormone receptor	0.048
Htr2b	5-hydroxytryptamine (serotonin) receptor 2B	0.048
Cpxm2	carboxypeptidase X 2 (M14 family)	0.048
Ptpn13	protein tyrosine phosphatase, non-receptor type 13	0.048
Homer1	homer homolog 1 (Drosophila)	0.047
Zfp52	zinc finger protein 52	0.047
Tph1	tryptophan hydroxylase 1	0.047
Mast3	microtubule associated serine/threonine kinase 3	0.047
Apoc3	apolipoprotein C-III	0.047
Hccs	holocytochrome c synthetase	0.047
Irs1	insulin receptor substrate 1	0.047
Porcn	porcupine homolog (Drosophila)	0.047
Tnni2	troponin I, skeletal, fast 2	0.047
Dok1	docking protein 1	0.047
Ccr2	chemokine (C-C motif) receptor 2	0.047
Duoxa1	dual oxidase maturation factor 1	0.046
Folr2	folate receptor 2 (fetal)	0.046
Saa3	serum amyloid A 3	0.046
Phox2a	paired-like homeobox 2a	0.046
Ogn	osteoglycin	0.046
Gjb5	gap junction protein, beta 5	0.046
Agtr1a	angiotensin II receptor, type 1a	0.046
Atp2c2	ATPase, Ca++ transporting, type 2C, member 2	0.046
Krt25	keratin 25	0.046
Prg4	proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)	0.046
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.046
Tcf3	transcription factor 3	0.046
Hopx	HOP homeobox	0.046
Ltbp1	latent transforming growth factor beta binding protein 1	0.046
Selp	selectin, platelet	0.046
Plxna4	plexin A4	0.046
Clic3	chloride intracellular channel 3	0.046
Gab2	growth factor receptor bound protein 2-associated protein 2	0.046
Icos	inducible T-cell co-stimulator	0.046
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.046
Lce1a1	late cornified envelope 1A1	0.045
Rgs10	regulator of G-protein signalling 10	0.045	Mouse
Fbn1	fibrillin 1	0.045
Apc	adenomatosis polyposis coli	0.045
Traf6	TNF receptor-associated factor 6	0.045
Hspb1	heat shock protein 1	0.045	Mouse
Map3k2	mitogen-activated protein kinase kinase kinase 2	0.045
Rab25	RAB25, member RAS oncogene family	0.045
Fosb	FBJ osteosarcoma oncogene B	0.045
Zfp651	zinc finger protein 651	0.045
Cmah	cytidine monophospho-N-acetylneuraminic acid hydroxylase	0.045
Enah	enabled homolog (Drosophila)	0.045
Rxra	retinoid X receptor alpha	0.045
Vapa	vesicle-associated membrane protein, associated protein A	0.045
Gdf5	growth differentiation factor 5	0.045
Rel	reticuloendotheliosis oncogene	0.045
Ephb2	Eph receptor B2	0.044
Slfn8	schlafen 8	0.044
Pum1	pumilio 1 (Drosophila)	0.044
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.044
Rcn1	reticulocalbin 1	0.044
Abl2	v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)	0.044
Rag2	recombination activating gene 2	0.044
Ptgs1	prostaglandin-endoperoxide synthase 1	0.044
Klf4	Kruppel-like factor 4 (gut)	0.044	Human
Lbp	lipopolysaccharide binding protein	0.044
Lce1c	late cornified envelope 1C	0.044
Slc46a2	solute carrier family 46, member 2	0.044
Hmgcs2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2	0.044
Krt1	keratin 1	0.044
Cyp2d26	cytochrome P450, family 2, subfamily d, polypeptide 26	0.044
Npn2	neoplastic progression 2	0.044
Klf2	Kruppel-like factor 2 (lung)	0.044
Mertk	c-mer proto-oncogene tyrosine kinase	0.044
Gata6	GATA binding protein 6	0.044
Mup19	major urinary protein 19	0.043
2210010C04Rik	RIKEN cDNA 2210010C04 gene	0.043
Cd96	CD96 antigen	0.043
Fasl	Fas ligand (TNF superfamily, member 6)	0.043	Mouse
Clip2	CAP-GLY domain containing linker protein 2	0.043
Stfa3	stefin A3	0.043	Human Mouse
Lce1h	late cornified envelope 1H	0.043
Stx4a	syntaxin 4A (placental)	0.043
Inhbb	inhibin beta-B	0.043
Lypd3	Ly6/Plaur domain containing 3	0.042
Serpina10	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.042	Fly
Frmd6	FERM domain containing 6	0.042
Entpd2	ectonucleoside triphosphate diphosphohydrolase 2	0.042
Sh3pxd2a	SH3 and PX domains 2A	0.042
Wnt4	wingless-related MMTV integration site 4	0.042	Mouse
Prl4a1	prolactin family 4, subfamily a, member 1	0.042
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.042
Pou3f2	POU domain, class 3, transcription factor 2	0.042
Nrk	Nik related kinase	0.041
Map3k6	mitogen-activated protein kinase kinase kinase 6	0.041
Cul9	cullin 9	0.041
Mcl1	myeloid cell leukemia sequence 1	0.041	Zebrafish
Raf1	v-raf-leukemia viral oncogene 1	0.041
Lpl	lipoprotein lipase	0.041
Ms4a4d	membrane-spanning 4-domains, subfamily A, member 4D	0.041
Orm2	orosomucoid 2	0.041
Tep1	telomerase associated protein 1	0.041
Nupr1	nuclear protein 1	0.041
Pax1	paired box gene 1	0.041
Dnajb4	DnaJ (Hsp40) homolog, subfamily B, member 4	0.041
Ptp4a2	protein tyrosine phosphatase 4a2	0.041
Gzmb	granzyme B	0.041
Pbxip1	pre-B-cell leukemia transcription factor interacting protein 1	0.041
Fn1	fibronectin 1	0.041
D19Wsu162e	DNA segment, Chr 19, Wayne State University 162, expressed	0.041
Il1f6	interleukin 1 family, member 6	0.041
Itga3	integrin alpha 3	0.041
Nedd9	neural precursor cell expressed, developmentally down-regulated gene 9	0.041
Smad7	MAD homolog 7 (Drosophila)	0.041
Csk	c-src tyrosine kinase	0.040
Cyp2d9	cytochrome P450, family 2, subfamily d, polypeptide 9	0.040
Flt1	FMS-like tyrosine kinase 1	0.040
Clca1	chloride channel calcium activated 1	0.040
Sprr1b	small proline-rich protein 1B	0.040
Sox10	SRY-box containing gene 10	0.040
Ahnak	AHNAK nucleoprotein (desmoyokin)	0.040
Bnc1	basonuclin 1	0.040
Vcam1	vascular cell adhesion molecule 1	0.040
Hoxd13	homeobox D13	0.040
Bgn	biglycan	0.040
Nt5e	5' nucleotidase, ecto	0.040
Wfdc12	WAP four-disulfide core domain 12	0.040
Pip4k2a	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	0.040
Tnfrsf11b	tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)	0.040
Cdc73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.040
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.040
Ctsj	cathepsin J	0.040
Tmbim1	transmembrane BAX inhibitor motif containing 1	0.040
Shc3	src homology 2 domain-containing transforming protein C3	0.039
Car12	carbonic anyhydrase 12	0.039
Lama4	laminin, alpha 4	0.039
Sycn	syncollin	0.039
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.039
Sprr2h	small proline-rich protein 2H	0.039
Dpt	dermatopontin	0.039
Tbk1	TANK-binding kinase 1	0.039
Klf7	Kruppel-like factor 7 (ubiquitous)	0.039
Nppb	natriuretic peptide type B	0.039
Ccnd1	cyclin D1	0.039
Nr4a2	nuclear receptor subfamily 4, group A, member 2	0.039	Mouse
Pou2af1	POU domain, class 2, associating factor 1	0.039
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.039
Plxnb3	plexin B3	0.039	Human
Serpinc1	serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1	0.039	Rat Fly
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.039	Mouse
Fscn1	fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)	0.039
Dmgdh	dimethylglycine dehydrogenase precursor	0.038
Elovl2	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2	0.038
Ppara	peroxisome proliferator activated receptor alpha	0.038
Lgi4	leucine-rich repeat LGI family, member 4	0.038
Itga1	integrin alpha 1	0.038
Actn2	actinin alpha 2	0.038
Csrp1	cysteine and glycine-rich protein 1	0.038
Nnmt	nicotinamide N-methyltransferase	0.038
Wwtr1	WW domain containing transcription regulator 1	0.038
Src	Rous sarcoma oncogene	0.038	Human
Zfp281	zinc finger protein 281	0.038
Serpinb3b	serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3B	0.038
Anxa3	annexin A3	0.038
Clec4d	C-type lectin domain family 4, member d	0.037
Nenf	neuron derived neurotrophic factor	0.037
Sqstm1	sequestosome 1	0.037
Ccr5	chemokine (C-C motif) receptor 5	0.037
Cacng1	calcium channel, voltage-dependent, gamma subunit 1	0.037
Ceacam9	carcinoembryonic antigen-related cell adhesion molecule 9	0.037
Anxa8	annexin A8	0.037	Human
Thbs1	thrombospondin 1	0.037	Human
Slc7a11	solute carrier family 7 (cationic amino acid transporter, y+ system), member 11	0.037
Lcat	lecithin cholesterol acyltransferase	0.037
Mug2	murinoglobulin 2	0.037
Mmp15	matrix metallopeptidase 15	0.037
Ctnna1	catenin (cadherin associated protein), alpha 1	0.037
Prl3a1	prolactin family 3, subfamily a, member 1	0.037
F2r	coagulation factor II (thrombin) receptor	0.037
Krtap3-3	keratin associated protein 3-3	0.036
Trhr2	thyrotropin releasing hormone receptor 2	0.036
Jun	Jun oncogene	0.036
Pdlim2	PDZ and LIM domain 2	0.036
Mmp3	matrix metallopeptidase 3	0.036
Apc2	adenomatosis polyposis coli 2	0.036
Mmp2	matrix metallopeptidase 2	0.036
Cd72	CD72 antigen	0.036
Fgfbp1	fibroblast growth factor binding protein 1	0.036
Vtn	vitronectin	0.036
Prmt1	protein arginine N-methyltransferase 1	0.036
Btc	betacellulin, epidermal growth factor family member	0.036
Npy1r	neuropeptide Y receptor Y1	0.036
Hgf	hepatocyte growth factor	0.036	Human
Ptk2b	PTK2 protein tyrosine kinase 2 beta	0.036
Mkl1	MKL (megakaryoblastic leukemia)/myocardin-like 1	0.036
Lpxn	leupaxin	0.036
Trim25	tripartite motif-containing 25	0.036
Coro1a	coronin, actin binding protein 1A	0.036
Dmkn	dermokine	0.035
Krt4	keratin 4	0.035
H2afx	H2A histone family, member X	0.035
Heatr2	HEAT repeat containing 2	0.035
Tubb5	tubulin, beta 5	0.035
Pfpl	pore forming protein-like	0.035
Gzmc	granzyme C	0.035
Fam83h	family with sequence similarity 83, member H	0.035
Pde6c	phosphodiesterase 6C, cGMP specific, cone, alpha prime	0.035
Cryab	crystallin, alpha B	0.035
Appl1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.035
Fzd4	frizzled homolog 4 (Drosophila)	0.035
A230046K03Rik	RIKEN cDNA A230046K03 gene	0.035
Gml	GPI anchored molecule like protein	0.035
2210407C18Rik	RIKEN cDNA 2210407C18 gene	0.035
Zbtb7b	zinc finger and BTB domain containing 7B	0.035
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.035
Tns1	tensin 1	0.035
Ppm1m	protein phosphatase 1M	0.035
Kl	klotho	0.035
Akp3	alkaline phosphatase 3, intestine, not Mn requiring	0.035
Capns2	calpain, small subunit 2	0.034
Omd	osteomodulin	0.034
Fgl2	fibrinogen-like protein 2	0.034
Tnip1	TNFAIP3 interacting protein 1	0.034
Rgs4	regulator of G-protein signaling 4	0.034	Mouse
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.034
Klf5	Kruppel-like factor 5	0.034
Slc6a6	solute carrier family 6 (neurotransmitter transporter, taurine), member 6	0.034
Mbp	myelin basic protein	0.034
Il13ra2	interleukin 13 receptor, alpha 2	0.034
Lgals3	lectin, galactose binding, soluble 3	0.034
Nod2	nucleotide-binding oligomerization domain containing 2	0.034
Dsg2	desmoglein 2	0.034
Ccm2	cerebral cavernous malformation 2 homolog (human)	0.034
Bhmt	betaine-homocysteine methyltransferase	0.034
Npas2	neuronal PAS domain protein 2	0.034
Rara	retinoic acid receptor, alpha	0.034
C1qtnf1	C1q and tumor necrosis factor related protein 1	0.034
Cyp2c38	cytochrome P450, family 2, subfamily c, polypeptide 38	0.034
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.034
Clu	clusterin	0.034
Rab17	RAB17, member RAS oncogene family	0.034
Lmod1	leiomodin 1 (smooth muscle)	0.034
Gnb2	guanine nucleotide binding protein (G protein), beta 2	0.034
Mapk12	mitogen-activated protein kinase 12	0.034
Rhob	ras homolog gene family, member B	0.034
Ephb6	Eph receptor B6	0.034
Cldn1	claudin 1	0.034
Ky	kyphoscoliosis peptidase	0.034
B4galnt2	beta-1,4-N-acetyl-galactosaminyl transferase 2	0.033
Dync1h1	dynein cytoplasmic 1 heavy chain 1	0.033
Sp100	nuclear antigen Sp100	0.033
Rho	rhodopsin	0.033
Krt19	keratin 19	0.033
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.033
Saa1	serum amyloid A 1	0.033
Agtr2	angiotensin II receptor, type 2	0.033
Ccl9	chemokine (C-C motif) ligand 9	0.033
Prss23	protease, serine, 23	0.033
Kcne1	potassium voltage-gated channel, Isk-related subfamily, member 1	0.033
Lama3	laminin, alpha 3	0.033
Npy	neuropeptide Y	0.033
Mylk2	myosin, light polypeptide kinase 2, skeletal muscle	0.033
Cxcr4	chemokine (C-X-C motif) receptor 4	0.033
F8	coagulation factor VIII	0.033
Rgs1	regulator of G-protein signaling 1	0.033	Mouse