IMP: Integrative Multi-species Prediction

Mus musculus

148 genes annotated in mouse

positive regulation of hydrolase activity

Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of hydrolase activity"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "positive regulation of hydrolase activity" (in gray)

Name	Description	Probability	Func Analog Organism
Lepr	leptin receptor	1.000
Trp53	transformation related protein 53	0.998	Zebrafish Fly
Bcl2	B-cell leukemia/lymphoma 2	0.964	Mouse Worm
Ctnnb1	catenin (cadherin associated protein), beta 1	0.929
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.926
Cd44	CD44 antigen	0.886
Itsn1	intersectin 1 (SH3 domain protein 1A)	0.868
Tnf	tumor necrosis factor	0.839
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.822	Mouse Fly
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.782
Ptprc	protein tyrosine phosphatase, receptor type, C	0.771
Cbl	Casitas B-lineage lymphoma	0.753
Nos3	nitric oxide synthase 3, endothelial cell	0.745
Vdr	vitamin D receptor	0.736
Ccr1	chemokine (C-C motif) receptor 1	0.735
Il2rg	interleukin 2 receptor, gamma chain	0.735
Bax	BCL2-associated X protein	0.734
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.709
Il1r1	interleukin 1 receptor, type I	0.699
Hdac7	histone deacetylase 7	0.697
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.666
Egfr	epidermal growth factor receptor	0.659	Mouse
Tgfbr2	transforming growth factor, beta receptor II	0.651
Nf1	neurofibromatosis 1	0.643
Pycard	PYD and CARD domain containing	0.632
Pnpla2	patatin-like phospholipase domain containing 2	0.626
Adam17	a disintegrin and metallopeptidase domain 17	0.621
Kl	klotho	0.618
Ldlr	low density lipoprotein receptor	0.609
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.595
Pten	phosphatase and tensin homolog	0.587
Vav1	vav 1 oncogene	0.579
Igh	immunoglobulin heavy chain complex	0.558
Mapk14	mitogen-activated protein kinase 14	0.542
Kit	kit oncogene	0.528
Invs	inversin	0.526
Rara	retinoic acid receptor, alpha	0.520
Apc	adenomatosis polyposis coli	0.515
Pip4k2a	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	0.510
Agtr1a	angiotensin II receptor, type 1a	0.509	Human
Ilk	integrin linked kinase	0.507
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.503	Mouse
Socs1	suppressor of cytokine signaling 1	0.488
Fbn1	fibrillin 1	0.481
Cd28	CD28 antigen	0.471
Rac1	RAS-related C3 botulinum substrate 1	0.470
Mcm4	minichromosome maintenance deficient 4 homolog (S. cerevisiae)	0.469
Hdac4	histone deacetylase 4	0.462
Vegfa	vascular endothelial growth factor A	0.461	Human
Mef2a	myocyte enhancer factor 2A	0.454	Mouse
Arhgef11	Rho guanine nucleotide exchange factor (GEF) 11	0.454
Hmha1	histocompatibility (minor) HA-1	0.451
Ltb	lymphotoxin B	0.444
Efnb2	ephrin B2	0.442
Braf	Braf transforming gene	0.441
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.440
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.439	Worm
Il10ra	interleukin 10 receptor, alpha	0.432
Arrb2	arrestin, beta 2	0.430
Tgfbr1	transforming growth factor, beta receptor I	0.427
Drd2	dopamine receptor D2	0.409
Wt1	Wilms tumor 1 homolog	0.407
Lrp1	low density lipoprotein receptor-related protein 1	0.401
Numb	numb gene homolog (Drosophila)	0.399
Eln	elastin	0.397
Lox	lysyl oxidase	0.393
Ncoa3	nuclear receptor coactivator 3	0.391
Casp1	caspase 1	0.390	Mouse Fly
Dnm1	dynamin 1	0.387
Tsc1	tuberous sclerosis 1	0.387	Human Fly
Trp73	transformation related protein 73	0.385	Fly
Lama5	laminin, alpha 5	0.370	Worm
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.365
Wrn	Werner syndrome homolog (human)	0.363	Human
Psme2	proteasome (prosome, macropain) 28 subunit, beta	0.363
Jak2	Janus kinase 2	0.361
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.357
Mlf2	myeloid leukemia factor 2	0.348
Plxna1	plexin A1	0.346	Mouse
Xiap	X-linked inhibitor of apoptosis	0.341
Lyst	lysosomal trafficking regulator	0.339
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.335
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.327
Rasgrp2	RAS, guanyl releasing protein 2	0.324	Human Mouse
Adrb1	adrenergic receptor, beta 1	0.320	Human Mouse
Scn5a	sodium channel, voltage-gated, type V, alpha	0.317
Selp	selectin, platelet	0.316
Hspd1	heat shock protein 1 (chaperonin)	0.315	Human
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.310
Stat5a	signal transducer and activator of transcription 5A	0.310	Mouse
Cav1	caveolin 1, caveolae protein	0.310
Birc3	baculoviral IAP repeat-containing 3	0.308
Adrb3	adrenergic receptor, beta 3	0.308	Mouse
Ikzf1	IKAROS family zinc finger 1	0.300
Irf1	interferon regulatory factor 1	0.300
Gbp5	guanylate binding protein 5	0.294
Fas	Fas (TNF receptor superfamily member 6)	0.292	Rat
Cyld	cylindromatosis (turban tumor syndrome)	0.289
Timm23	translocase of inner mitochondrial membrane 23 homolog (yeast)	0.286
Ret	ret proto-oncogene	0.284	Human
Cd151	CD151 antigen	0.277
Epha4	Eph receptor A4	0.276	Human
Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.272
Rtkn	rhotekin	0.269
Cxcl13	chemokine (C-X-C motif) ligand 13	0.268
Ar	androgen receptor	0.267
Hdac5	histone deacetylase 5	0.263
Pxn	paxillin	0.263
Ptpn2	protein tyrosine phosphatase, non-receptor type 2	0.262
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.261
Epha1	Eph receptor A1	0.261	Human
Ptgs2	prostaglandin-endoperoxide synthase 2	0.259
Phldb2	pleckstrin homology-like domain, family B, member 2	0.258
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.257	Mouse
Notch2	Notch gene homolog 2 (Drosophila)	0.257
Hif1a	hypoxia inducible factor 1, alpha subunit	0.256
Ccl2	chemokine (C-C motif) ligand 2	0.254
Pdgfb	platelet derived growth factor, B polypeptide	0.248
Casp8	caspase 8	0.247
Parva	parvin, alpha	0.246
Phldb1	pleckstrin homology-like domain, family B, member 1	0.246
Stxbp3a	syntaxin binding protein 3A	0.245
Npr2	natriuretic peptide receptor 2	0.244
Prkce	protein kinase C, epsilon	0.244
Wipf1	WAS/WASL interacting protein family, member 1	0.244
Pafah1b1	platelet-activating factor acetylhydrolase, isoform 1b, subunit 1	0.244
Abi1	abl-interactor 1	0.243
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.242
Thbs1	thrombospondin 1	0.238
Pno1	partner of NOB1 homolog (S. cerevisiae)	0.237
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.237	Human
Dek	DEK oncogene (DNA binding)	0.237
Lamb2	laminin, beta 2	0.232
Itga3	integrin alpha 3	0.232
Vav2	vav 2 oncogene	0.231
Gmnn	geminin	0.231
Gata6	GATA binding protein 6	0.231
Mcl1	myeloid cell leukemia sequence 1	0.228	Mouse Worm
Psen1	presenilin 1	0.227
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.227
Ntf3	neurotrophin 3	0.226
Cd40	CD40 antigen	0.225	Human
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.225	Human Fly
Jag2	jagged 2	0.225
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.225
Cd160	CD160 antigen	0.223
Psmc3	proteasome (prosome, macropain) 26S subunit, ATPase 3	0.218
Chrm1	cholinergic receptor, muscarinic 1, CNS	0.217
Acvr1	activin A receptor, type 1	0.216
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.213	Mouse
Bglap	bone gamma carboxyglutamate protein	0.211
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.208	Human
Fli1	Friend leukemia integration 1	0.204
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.203
Pparg	peroxisome proliferator activated receptor gamma	0.203	Human
Il27ra	interleukin 27 receptor, alpha	0.203
Npm1	nucleophosmin 1	0.202
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.200
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.200	Mouse
Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.200
Add1	adducin 1 (alpha)	0.200
Ptk2b	PTK2 protein tyrosine kinase 2 beta	0.199	Rat
Cep290	centrosomal protein 290	0.199
Mndal	myeloid nuclear differentiation antigen like	0.199
Nos2	nitric oxide synthase 2, inducible	0.198
Map4k2	mitogen-activated protein kinase kinase kinase kinase 2	0.198
Psmc2	proteasome (prosome, macropain) 26S subunit, ATPase 2	0.193
Eps15	epidermal growth factor receptor pathway substrate 15	0.193
Cd2ap	CD2-associated protein	0.192
Fyn	Fyn proto-oncogene	0.192	Mouse
Cttn	cortactin	0.191
Apaf1	apoptotic peptidase activating factor 1	0.190
Nf2	neurofibromatosis 2	0.187
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.186
Fgfr1	fibroblast growth factor receptor 1	0.184	Human
Fgfr2	fibroblast growth factor receptor 2	0.184	Human
Psmd12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	0.184
Smo	smoothened homolog (Drosophila)	0.183
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.183	Human
Morc3	microrchidia 3	0.183
Bcl2l1	BCL2-like 1	0.181	Mouse Worm
Ephb2	Eph receptor B2	0.181
Ednra	endothelin receptor type A	0.179
Cdk14	cyclin-dependent kinase 14	0.179
Notch1	Notch gene homolog 1 (Drosophila)	0.179
Osmr	oncostatin M receptor	0.178
Rasgrp1	RAS guanyl releasing protein 1	0.177
Ptk2	PTK2 protein tyrosine kinase 2	0.176
Nphs2	nephrosis 2 homolog, podocin (human)	0.175
Ren1	renin 1 structural	0.173
Ptch1	patched homolog 1	0.173
Sh3rf1	SH3 domain containing ring finger 1	0.173
Shc3	src homology 2 domain-containing transforming protein C3	0.173
Igf2	insulin-like growth factor 2	0.172
Bmp1	bone morphogenetic protein 1	0.171
Il2rb	interleukin 2 receptor, beta chain	0.170
Sema4d	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	0.170
Epb4.1l2	erythrocyte protein band 4.1-like 2	0.169
Raf1	v-raf-leukemia viral oncogene 1	0.169
Arhgef7	Rho guanine nucleotide exchange factor (GEF7)	0.167
Sox10	SRY-box containing gene 10	0.167
Becn1	beclin 1, autophagy related	0.167
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.166	Rat
Magi1	membrane associated guanylate kinase, WW and PDZ domain containing 1	0.166
Cxcr4	chemokine (C-X-C motif) receptor 4	0.166
Sema3e	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E	0.165
Mdm2	transformed mouse 3T3 cell double minute 2	0.165
Dab2	disabled homolog 2 (Drosophila)	0.164
Ndel1	nuclear distribution gene E-like homolog 1 (A. nidulans)	0.164
Smc4	structural maintenance of chromosomes 4	0.163
Abl2	v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)	0.163	Human
Socs3	suppressor of cytokine signaling 3	0.163
Mapk8	mitogen-activated protein kinase 8	0.163	Human
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.163
Cpd	carboxypeptidase D	0.162
Plxna3	plexin A3	0.162	Mouse
Il6st	interleukin 6 signal transducer	0.162
Vav3	vav 3 oncogene	0.162
Vcl	vinculin	0.161
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.160	Mouse
Coro1b	coronin, actin binding protein 1B	0.160
Zeb1	zinc finger E-box binding homeobox 1	0.158
Rbl1	retinoblastoma-like 1 (p107)	0.158
Dll1	delta-like 1 (Drosophila)	0.158
Slit3	slit homolog 3 (Drosophila)	0.157
Ncor2	nuclear receptor co-repressor 2	0.157
Ctsk	cathepsin K	0.156
Sh3bp1	SH3-domain binding protein 1	0.155	Fly
Skil	SKI-like	0.155
Traf1	TNF receptor-associated factor 1	0.155
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.155
A230046K03Rik	RIKEN cDNA A230046K03 gene	0.154
Glis2	GLIS family zinc finger 2	0.153
Apob	apolipoprotein B	0.153
Gpsm3	G-protein signalling modulator 3 (AGS3-like, C. elegans)	0.152
Rb1	retinoblastoma 1	0.152
Fnip1	folliculin interacting protein 1	0.152
Ehmt2	euchromatic histone lysine N-methyltransferase 2	0.151
Pstpip1	proline-serine-threonine phosphatase-interacting protein 1	0.151
Bcl6	B-cell leukemia/lymphoma 6	0.150
Rxra	retinoid X receptor alpha	0.149
Rgnef	Rho-guanine nucleotide exchange factor	0.148
Npy1r	neuropeptide Y receptor Y1	0.148
Adrbk1	adrenergic receptor kinase, beta 1	0.147
Adam10	a disintegrin and metallopeptidase domain 10	0.146
Il7r	interleukin 7 receptor	0.146
Cd37	CD37 antigen	0.146
Dbnl	drebrin-like	0.146
Tcf3	transcription factor 3	0.145
Timm17a	translocase of inner mitochondrial membrane 17a	0.145
Tcra	T-cell receptor alpha chain	0.144
Fgfr4	fibroblast growth factor receptor 4	0.143
Sstr4	somatostatin receptor 4	0.143
Fgf5	fibroblast growth factor 5	0.142
Nckap1	NCK-associated protein 1	0.142
Casp3	caspase 3	0.141	Mouse
Nbl1	neuroblastoma, suppression of tumorigenicity 1	0.141
Il7	interleukin 7	0.141
Iqsec1	IQ motif and Sec7 domain 1	0.140
Cd247	CD247 antigen	0.140
Ptprf	protein tyrosine phosphatase, receptor type, F	0.140
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.140
Foxa2	forkhead box A2	0.139
Srgap2	SLIT-ROBO Rho GTPase activating protein 2	0.139
Stk3	serine/threonine kinase 3 (Ste20, yeast homolog)	0.139
Ephb3	Eph receptor B3	0.139
Ptpre	protein tyrosine phosphatase, receptor type, E	0.137
Agap2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	0.137	Worm Fly
Arpc4	actin related protein 2/3 complex, subunit 4	0.137
Ikbke	inhibitor of kappaB kinase epsilon	0.137	Fly
Psme1	proteasome (prosome, macropain) 28 subunit, alpha	0.135
Nckap1l	NCK associated protein 1 like	0.135
Pkd2	polycystic kidney disease 2	0.135
Wdr26	WD repeat domain 26	0.135
Spnb2	spectrin beta 2	0.135
Col4a2	collagen, type IV, alpha 2	0.134
Arhgef6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6	0.134	Mouse
Asap1	ArfGAP with SH# domain, ankyrin repeat and PH domain1	0.134
Arhgap30	Rho GTPase activating protein 30	0.134	Mouse
Dock9	dedicator of cytokinesis 9	0.134
Psma4	proteasome (prosome, macropain) subunit, alpha type 4	0.134
Ccr2	chemokine (C-C motif) receptor 2	0.134
Irf5	interferon regulatory factor 5	0.133
Rel	reticuloendotheliosis oncogene	0.133
Pou2af1	POU domain, class 2, associating factor 1	0.132
Epb4.9	erythrocyte protein band 4.9	0.132
Psma2	proteasome (prosome, macropain) subunit, alpha type 2	0.131
Mybpc3	myosin binding protein C, cardiac	0.131
Nptx1	neuronal pentraxin 1	0.131
Lrrk2	leucine-rich repeat kinase 2	0.131	Human
Smarcd1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.131
Psmd4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	0.130
Psmd6	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	0.130
Mtap2	microtubule-associated protein 2	0.128
Prss32	protease, serine, 32	0.128
Tubb2c	tubulin, beta 2C	0.128
Actb	actin, beta	0.128
Bcr	breakpoint cluster region	0.127
Was	Wiskott-Aldrich syndrome homolog (human)	0.126
Hcls1	hematopoietic cell specific Lyn substrate 1	0.125
Icos	inducible T-cell co-stimulator	0.125
Wnt7a	wingless-related MMTV integration site 7A	0.125	Mouse
Htt	huntingtin	0.124
Kifc2	kinesin family member C2	0.124
Lta	lymphotoxin A	0.124	Mouse
Mef2c	myocyte enhancer factor 2C	0.124
Ptgir	prostaglandin I receptor (IP)	0.123
Gja1	gap junction protein, alpha 1	0.123
Grb2	growth factor receptor bound protein 2	0.123
Rab5a	RAB5A, member RAS oncogene family	0.123
Psmb6	proteasome (prosome, macropain) subunit, beta type 6	0.123
Cux1	cut-like homeobox 1	0.122
Nrbp2	nuclear receptor binding protein 2	0.121
Zfr2	zinc finger RNA binding protein 2	0.121
Kif23	kinesin family member 23	0.121
Kcnk4	potassium channel, subfamily K, member 4	0.121
Irf8	interferon regulatory factor 8	0.120
Sell	selectin, lymphocyte	0.119
Sema3b	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	0.119	Mouse
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.119	Human
Lamc2	laminin, gamma 2	0.118
Huwe1	HECT, UBA and WWE domain containing 1	0.118
Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like	0.118
Pdcd10	programmed cell death 10	0.118
Psmb5	proteasome (prosome, macropain) subunit, beta type 5	0.117
Nmi	N-myc (and STAT) interactor	0.117
Sh2d2a	SH2 domain protein 2A	0.116
Pcdh12	protocadherin 12	0.116
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.116
Kalrn	kalirin, RhoGEF kinase	0.115	Mouse Worm Fly
Galnt6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6	0.115
Pdcd6ip	programmed cell death 6 interacting protein	0.115
L1cam	L1 cell adhesion molecule	0.114
Rgl2	ral guanine nucleotide dissociation stimulator-like 2	0.114	Mouse
Msh2	mutS homolog 2 (E. coli)	0.114	Human
Fgf4	fibroblast growth factor 4	0.114
Men1	multiple endocrine neoplasia 1	0.114
Irf9	interferon regulatory factor 9	0.114
Casp7	caspase 7	0.114	Mouse
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.114
Tcf7	transcription factor 7, T-cell specific	0.114
Klf5	Kruppel-like factor 5	0.113
Efs	embryonal Fyn-associated substrate	0.113
Lck	lymphocyte protein tyrosine kinase	0.113	Human Mouse
Ctdspl	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like	0.112
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.111
Nog	noggin	0.111
Psmb7	proteasome (prosome, macropain) subunit, beta type 7	0.111
Idua	iduronidase, alpha-L-	0.111
Adam11	a disintegrin and metallopeptidase domain 11	0.111
Lamb1	laminin B1	0.111
Kif3a	kinesin family member 3A	0.111
Tcrd	T-cell receptor delta chain	0.111
Il22	interleukin 22	0.111	Mouse
Fnbp1	formin binding protein 1	0.111
Numa1	nuclear mitotic apparatus protein 1	0.110
Gdnf	glial cell line derived neurotrophic factor	0.110
C1qtnf1	C1q and tumor necrosis factor related protein 1	0.110
Cpxm1	carboxypeptidase X 1 (M14 family)	0.110
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.109
Sav1	salvador homolog 1 (Drosophila)	0.109
Mib1	mindbomb homolog 1 (Drosophila)	0.109
Stk4	serine/threonine kinase 4	0.109
Gpr27	G protein-coupled receptor 27	0.108
Acvrl1	activin A receptor, type II-like 1	0.108
Fgf3	fibroblast growth factor 3	0.108
Map3k5	mitogen-activated protein kinase kinase kinase 5	0.108	Human
Ncoa1	nuclear receptor coactivator 1	0.107
Palm	paralemmin	0.107
Vhl	von Hippel-Lindau tumor suppressor	0.107
Tmem131	transmembrane protein 131	0.106
Elmo1	engulfment and cell motility 1, ced-12 homolog (C. elegans)	0.106
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.106
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.105
Gsk3b	glycogen synthase kinase 3 beta	0.105	Human
Efna1	ephrin A1	0.105
Pla2g4a	phospholipase A2, group IVA (cytosolic, calcium-dependent)	0.105
Grin2d	glutamate receptor, ionotropic, NMDA2D (epsilon 4)	0.105
Hspa8	heat shock protein 8	0.105
Card11	caspase recruitment domain family, member 11	0.105
Dkk3	dickkopf homolog 3 (Xenopus laevis)	0.105
Ednrb	endothelin receptor type B	0.104
Psma1	proteasome (prosome, macropain) subunit, alpha type 1	0.104
Ccbp2	chemokine binding protein 2	0.104
Tox	thymocyte selection-associated high mobility group box	0.104
Mmp2	matrix metallopeptidase 2	0.104
Git1	G protein-coupled receptor kinase-interactor 1	0.104	Rat
Apoe	apolipoprotein E	0.103
Ppp1r9b	protein phosphatase 1, regulatory subunit 9B	0.103
Ctnnd1	catenin (cadherin associated protein), delta 1	0.103
Galntl1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1	0.103
Mtmr6	myotubularin related protein 6	0.102
Ptprj	protein tyrosine phosphatase, receptor type, J	0.101
Abp1	amiloride binding protein 1 (amine oxidase, copper-containing)	0.101
Iqcb1	IQ calmodulin-binding motif containing 1	0.101
Ccl22	chemokine (C-C motif) ligand 22	0.100
Ifng	interferon gamma	0.100
Lpin1	lipin 1	0.100
Dock10	dedicator of cytokinesis 10	0.100
Fscn1	fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)	0.100
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.100
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.100
Fstl1	follistatin-like 1	0.100
Trpm5	transient receptor potential cation channel, subfamily M, member 5	0.099
Foxn1	forkhead box N1	0.099
Rasa1	RAS p21 protein activator 1	0.099	Fly
Adra2b	adrenergic receptor, alpha 2b	0.099	Mouse
Il18	interleukin 18	0.099
Fadd	Fas (TNFRSF6)-associated via death domain	0.099	Human
Bcar1	breast cancer anti-estrogen resistance 1	0.099
Ngf	nerve growth factor	0.098
Phlpp1	PH domain and leucine rich repeat protein phosphatase 1	0.098
Etf1	eukaryotic translation termination factor 1	0.098
Pik3c2a	phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide	0.098
Sp100	nuclear antigen Sp100	0.098
Nrp1	neuropilin 1	0.097
Mfn2	mitofusin 2	0.097
Mmp15	matrix metallopeptidase 15	0.097
Ptpru	protein tyrosine phosphatase, receptor type, U	0.097
Fzd6	frizzled homolog 6 (Drosophila)	0.097
Ccl4	chemokine (C-C motif) ligand 4	0.097	Mouse
Swap70	SWA-70 protein	0.097
Rasal3	RAS protein activator like 3	0.097
Prkcc	protein kinase C, gamma	0.097	Mouse
Grb7	growth factor receptor bound protein 7	0.097
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.096
Psma3	proteasome (prosome, macropain) subunit, alpha type 3	0.096
Tmpo	thymopoietin	0.096
Arhgap21	Rho GTPase activating protein 21	0.096
Dapk1	death associated protein kinase 1	0.096
Tlr4	toll-like receptor 4	0.096
Mmp12	matrix metallopeptidase 12	0.095
Dll4	delta-like 4 (Drosophila)	0.095
Tbx2	T-box 2	0.095
Id2	inhibitor of DNA binding 2	0.095
Pld1	phospholipase D1	0.094
Sorl1	sortilin-related receptor, LDLR class A repeats-containing	0.094
Akt3	thymoma viral proto-oncogene 3	0.094	Mouse
B3gat1	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)	0.094
Eif3j	eukaryotic translation initiation factor 3, subunit J	0.094
Cd6	CD6 antigen	0.094
Psma7	proteasome (prosome, macropain) subunit, alpha type 7	0.093
Bub1b	budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)	0.093
Prrx2	paired related homeobox 2	0.093
Tsc2	tuberous sclerosis 2	0.093	Human Rat Fly
Sh2b1	SH2B adaptor protein 1	0.092
Nbeal2	neurobeachin-like 2	0.092
Fmnl3	formin-like 3	0.092
Adora2a	adenosine A2a receptor	0.092
Rap1gap	Rap1 GTPase-activating protein	0.092	Human Mouse
Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isoform	0.092
Cxcr5	chemokine (C-X-C motif) receptor 5	0.092
Erap1	endoplasmic reticulum aminopeptidase 1	0.092
Il18rap	interleukin 18 receptor accessory protein	0.091
Nrp2	neuropilin 2	0.091
Zdhhc17	zinc finger, DHHC domain containing 17	0.091
Hgf	hepatocyte growth factor	0.091
Tspan9	tetraspanin 9	0.091
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.091
Plekha1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	0.091
Ctnna1	catenin (cadherin associated protein), alpha 1	0.091
Klf6	Kruppel-like factor 6	0.091
Ch25h	cholesterol 25-hydroxylase	0.090
Hip1	huntingtin interacting protein 1	0.090	Human
Fndc1	fibronectin type III domain containing 1	0.090
Rnf115	ring finger protein 115	0.089
Limk2	LIM motif-containing protein kinase 2	0.089
Rph3a	rabphilin 3A	0.089
Inhbc	inhibin beta-C	0.089
Lcp2	lymphocyte cytosolic protein 2	0.089
Kitl	kit ligand	0.089
Anxa4	annexin A4	0.089
Rasal2	RAS protein activator like 2	0.089
Ltbp3	latent transforming growth factor beta binding protein 3	0.088	Mouse
Sele	selectin, endothelial cell	0.088	Human
Vangl2	vang-like 2 (van gogh, Drosophila)	0.088
Cttnbp2nl	CTTNBP2 N-terminal like	0.088
Shroom1	shroom family member 1	0.088
Clec3b	C-type lectin domain family 3, member b	0.088
Wnt6	wingless-related MMTV integration site 6	0.087	Mouse
Trpv2	transient receptor potential cation channel, subfamily V, member 2	0.087
Cdh1	cadherin 1	0.087
Aim2	absent in melanoma 2	0.087
Col4a5	collagen, type IV, alpha 5	0.087
Igf1r	insulin-like growth factor I receptor	0.087
Zeb2	zinc finger E-box binding homeobox 2	0.087
Cybb	cytochrome b-245, beta polypeptide	0.087
Hspe1	heat shock protein 1 (chaperonin 10)	0.086
Ptch2	patched homolog 2	0.086
Plcg1	phospholipase C, gamma 1	0.086
Mprip	myosin phosphatase Rho interacting protein	0.086
Tcf21	transcription factor 21	0.086
Ikzf3	IKAROS family zinc finger 3	0.086
Pdcd1	programmed cell death 1	0.086
Mid2	midline 2	0.086
Htr1d	5-hydroxytryptamine (serotonin) receptor 1D	0.086	Mouse
Cyr61	cysteine rich protein 61	0.086
Psmb2	proteasome (prosome, macropain) subunit, beta type 2	0.085	Yeast
Pygo2	pygopus 2	0.085
Dnm1l	dynamin 1-like	0.085
Tgfb1	transforming growth factor, beta 1	0.085
Cxadr	coxsackie virus and adenovirus receptor	0.085
Ptpn12	protein tyrosine phosphatase, non-receptor type 12	0.085
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.084
Cox4i2	cytochrome c oxidase subunit IV isoform 2	0.084
Map4k3	mitogen-activated protein kinase kinase kinase kinase 3	0.084
Abr	active BCR-related gene	0.084
Itgb4	integrin beta 4	0.084
Bdnf	brain derived neurotrophic factor	0.084
Itch	itchy, E3 ubiquitin protein ligase	0.084
Slfn1	schlafen 1	0.084
Tcap	titin-cap	0.084
Pkd1	polycystic kidney disease 1 homolog	0.084
Colec12	collectin sub-family member 12	0.084
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.084
Nr1h3	nuclear receptor subfamily 1, group H, member 3	0.084	Human
Tbk1	TANK-binding kinase 1	0.083	Fly
Kpna2	karyopherin (importin) alpha 2	0.083
Slc4a3	solute carrier family 4 (anion exchanger), member 3	0.083
Bicd2	bicaudal D homolog 2 (Drosophila)	0.083
Sh3d19	SH3 domain protein D19	0.083
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.082
Nedd9	neural precursor cell expressed, developmentally down-regulated gene 9	0.082
Fgf2	fibroblast growth factor 2	0.082	Human
Lima1	LIM domain and actin binding 1	0.082
Sipa1l2	signal-induced proliferation-associated 1 like 2	0.082
Cpz	carboxypeptidase Z	0.082
Arap3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.082
Sbf1	SET binding factor 1	0.082	Human Mouse Fly
Tead3	TEA domain family member 3	0.082
Abcc6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	0.082
Cdh6	cadherin 6	0.082
Igf2r	insulin-like growth factor 2 receptor	0.082
Vim	vimentin	0.081
Spg21	spastic paraplegia 21 homolog (human)	0.081
Ccnd1	cyclin D1	0.081
Fzd8	frizzled homolog 8 (Drosophila)	0.081
Gnb2	guanine nucleotide binding protein (G protein), beta 2	0.081
Arhgef12	Rho guanine nucleotide exchange factor (GEF) 12	0.081	Fly
Chst2	carbohydrate sulfotransferase 2	0.081
Lrp5	low density lipoprotein receptor-related protein 5	0.081
Far1	fatty acyl CoA reductase 1	0.081
Tank	TRAF family member-associated Nf-kappa B activator	0.080
Stk10	serine/threonine kinase 10	0.080
Ptprs	protein tyrosine phosphatase, receptor type, S	0.080
Atp8a1	ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1	0.080
Hipk3	homeodomain interacting protein kinase 3	0.080
Mmp11	matrix metallopeptidase 11	0.080
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.079
Wnt7b	wingless-related MMTV integration site 7B	0.079	Mouse
Il2	interleukin 2	0.079
Sae1	SUMO1 activating enzyme subunit 1	0.079
Stim2	stromal interaction molecule 2	0.079
Thbs3	thrombospondin 3	0.079
Clock	circadian locomotor output cycles kaput	0.079
Psma5	proteasome (prosome, macropain) subunit, alpha type 5	0.079
Mmp13	matrix metallopeptidase 13	0.078
Nrg1	neuregulin 1	0.078
Batf	basic leucine zipper transcription factor, ATF-like	0.078
Dusp1	dual specificity phosphatase 1	0.078
Ppa1	pyrophosphatase (inorganic) 1	0.078
Ccl12	chemokine (C-C motif) ligand 12	0.078	Mouse
Prlr	prolactin receptor	0.077
Mpp5	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)	0.077
Mobkl1b	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.077
Itsn2	intersectin 2	0.077
Fbxo38	F-box protein 38	0.077
Arf6	ADP-ribosylation factor 6	0.077
Pecam1	platelet/endothelial cell adhesion molecule 1	0.077
BC021891	cDNA sequence BC021891	0.077
Icam1	intercellular adhesion molecule 1	0.077	Rat
C230081A13Rik	RIKEN cDNA C230081A13 gene	0.077
Axin1	axin 1	0.077
Itga5	integrin alpha 5 (fibronectin receptor alpha)	0.077
Cd93	CD93 antigen	0.076
Lag3	lymphocyte-activation gene 3	0.076
Pik3r5	phosphoinositide-3-kinase, regulatory subunit 5, p101	0.076
Saa3	serum amyloid A 3	0.076
Fgf15	fibroblast growth factor 15	0.076
Nsfl1c	NSFL1 (p97) cofactor (p47)	0.076
Insr	insulin receptor	0.076
Guca2b	guanylate cyclase activator 2b (retina)	0.076
Itih1	inter-alpha trypsin inhibitor, heavy chain 1	0.076
Loxl1	lysyl oxidase-like 1	0.076
Ets2	E26 avian leukemia oncogene 2, 3' domain	0.076
Wwtr1	WW domain containing transcription regulator 1	0.075
Cyp1a1	cytochrome P450, family 1, subfamily a, polypeptide 1	0.075
Fam105a	family with sequence similarity 105, member A	0.075
Ggta1	glycoprotein galactosyltransferase alpha 1, 3	0.075
Zfp51	zinc finger protein 51	0.075
Crybb2	crystallin, beta B2	0.075
Jak1	Janus kinase 1	0.075	Mouse
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.075
Grid1	glutamate receptor, ionotropic, delta 1	0.075
Cacnb3	calcium channel, voltage-dependent, beta 3 subunit	0.075
Ccr1l1	chemokine (C-C motif) receptor 1-like 1	0.075
Arvcf	armadillo repeat gene deleted in velo-cardio-facial syndrome	0.075
Irf4	interferon regulatory factor 4	0.075
Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1	0.074
E2f1	E2F transcription factor 1	0.074
Chuk	conserved helix-loop-helix ubiquitous kinase	0.074
Wnt3	wingless-related MMTV integration site 3	0.074	Mouse
Hivep2	human immunodeficiency virus type I enhancer binding protein 2	0.074
Col13a1	collagen, type XIII, alpha 1	0.074
Mgp	matrix Gla protein	0.074
Fgf23	fibroblast growth factor 23	0.074
Tnfrsf8	tumor necrosis factor receptor superfamily, member 8	0.074
Trex2	three prime repair exonuclease 2	0.074
Ids	iduronate 2-sulfatase	0.074
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.074
Uvrag	UV radiation resistance associated gene	0.074
Rbm3	RNA binding motif protein 3	0.074
Ect2	ect2 oncogene	0.074	Human Fly
Fmod	fibromodulin	0.073
Ptprk	protein tyrosine phosphatase, receptor type, K	0.073
Kcnh3	potassium voltage-gated channel, subfamily H (eag-related), member 3	0.073
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.073
Adcy4	adenylate cyclase 4	0.073
Ube4b	ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)	0.073
Prrx1	paired related homeobox 1	0.073
Atp2a3	ATPase, Ca++ transporting, ubiquitous	0.073	Fly
Asxl1	additional sex combs like 1 (Drosophila)	0.073
Eif5b	eukaryotic translation initiation factor 5B	0.073
Tmod3	tropomodulin 3	0.073
Klc1	kinesin light chain 1	0.073
Cdk18	cyclin-dependent kinase 18	0.073
Fnbp1l	formin binding protein 1-like	0.073
Rasa3	RAS p21 protein activator 3	0.073	Fly
Wnt2	wingless-related MMTV integration site 2	0.073	Mouse
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.073
Pvrl1	poliovirus receptor-related 1	0.073
P2ry6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.073
Vdac3	voltage-dependent anion channel 3	0.073
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.072
Sall1	sal-like 1 (Drosophila)	0.072
Myo15	myosin XV	0.072
Lbr	lamin B receptor	0.072
Llgl1	lethal giant larvae homolog 1 (Drosophila)	0.072	Rat
AI607873	expressed sequence AI607873	0.072
Hnf1a	HNF1 homeobox A	0.071
Flt1	FMS-like tyrosine kinase 1	0.071	Human
Mmp9	matrix metallopeptidase 9	0.071
Plxnb1	plexin B1	0.071
Myo1e	myosin IE	0.071
Tnks1bp1	tankyrase 1 binding protein 1	0.071
Ppp1ca	protein phosphatase 1, catalytic subunit, alpha isoform	0.071
Adarb1	adenosine deaminase, RNA-specific, B1	0.071
Sstr1	somatostatin receptor 1	0.071
Cdx1	caudal type homeobox 1	0.071
Pde1b	phosphodiesterase 1B, Ca2+-calmodulin dependent	0.071
Rapsn	receptor-associated protein of the synapse	0.071
Cx3cl1	chemokine (C-X3-C motif) ligand 1	0.071
Smpd3	sphingomyelin phosphodiesterase 3, neutral	0.071
Plxna4	plexin A4	0.071	Mouse
Src	Rous sarcoma oncogene	0.071	Mouse
Adam23	a disintegrin and metallopeptidase domain 23	0.071
Dnajb9	DnaJ (Hsp40) homolog, subfamily B, member 9	0.071
Fpr2	formyl peptide receptor 2	0.071
S100a5	S100 calcium binding protein A5	0.071
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.071
Hsp90b1	heat shock protein 90, beta (Grp94), member 1	0.071
Mycl1	v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)	0.071	Mouse
BC020535	cDNA sequence BC020535	0.071
Vcan	versican	0.071
Foxk1	forkhead box K1	0.071
Ncf1	neutrophil cytosolic factor 1	0.071
Traf3ip2	TRAF3 interacting protein 2	0.070
Polg	polymerase (DNA directed), gamma	0.070
Rfwd2	ring finger and WD repeat domain 2	0.070
Ptprm	protein tyrosine phosphatase, receptor type, M	0.070
Irf6	interferon regulatory factor 6	0.070
Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3	0.070
Cycs	cytochrome c, somatic	0.070
Nynrin	NYN domain and retroviral integrase containing	0.070
Dock5	dedicator of cytokinesis 5	0.070
Srrt	serrate RNA effector molecule homolog (Arabidopsis)	0.070
Col6a2	collagen, type VI, alpha 2	0.070
Spry4	sprouty homolog 4 (Drosophila)	0.070
Timeless	timeless homolog (Drosophila)	0.070
Hbb-b1	hemoglobin, beta adult major chain	0.070
Baiap2	brain-specific angiogenesis inhibitor 1-associated protein 2	0.070
Ubc	ubiquitin C	0.070
Ltbp1	latent transforming growth factor beta binding protein 1	0.070	Mouse
Vapa	vesicle-associated membrane protein, associated protein A	0.070
Cxcl1	chemokine (C-X-C motif) ligand 1	0.069
Rap1b	RAS related protein 1b	0.069
Git2	G protein-coupled receptor kinase-interactor 2	0.069
Acap1	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	0.069
Apbb1	amyloid beta (A4) precursor protein-binding, family B, member 1	0.069
Fgfrl1	fibroblast growth factor receptor-like 1	0.069
Cpne3	copine III	0.069
Itgax	integrin alpha X	0.068
Wls	wntless homolog (Drosophila)	0.068
Ifi204	interferon activated gene 204	0.068	Human
2010106G01Rik	RIKEN cDNA 2010106G01 gene	0.068
Il15	interleukin 15	0.068
Vdac2	voltage-dependent anion channel 2	0.068
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.068
Ccdc88a	coiled coil domain containing 88A	0.068
Adrb2	adrenergic receptor, beta 2	0.068	Mouse Rat
Strn	striatin, calmodulin binding protein	0.068
Slc34a2	solute carrier family 34 (sodium phosphate), member 2	0.068
Ate1	arginyltransferase 1	0.067
Cdc42se1	CDC42 small effector 1	0.067
Strn3	striatin, calmodulin binding protein 3	0.067
Hspa5	heat shock protein 5	0.067
Zfp36l2	zinc finger protein 36, C3H type-like 2	0.067
Col5a2	collagen, type V, alpha 2	0.067
Ints3	integrator complex subunit 3	0.067
Ccdc24	coiled-coil domain containing 24	0.067
Ntng2	netrin G2	0.067
Ehd3	EH-domain containing 3	0.067
Plscr1	phospholipid scramblase 1	0.067	Human
Ggt5	gamma-glutamyltransferase 5	0.067
Rapgef4	Rap guanine nucleotide exchange factor (GEF) 4	0.067
Prkcb	protein kinase C, beta	0.067
Ghrl	ghrelin	0.067
Inpp4a	inositol polyphosphate-4-phosphatase, type I	0.067
Tgfa	transforming growth factor alpha	0.067
Agtr2	angiotensin II receptor, type 2	0.066	Human
Gsx1	GS homeobox 1	0.066
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.066
Kcna3	potassium voltage-gated channel, shaker-related subfamily, member 3	0.066
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.066
Rasgrf2	RAS protein-specific guanine nucleotide-releasing factor 2	0.066	Mouse
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.066
Cfh	complement component factor h	0.066
Icam5	intercellular adhesion molecule 5, telencephalin	0.066
Tnip1	TNFAIP3 interacting protein 1	0.066
Endou	endonuclease, polyU-specific	0.066
Porcn	porcupine homolog (Drosophila)	0.066
Svil	supervillin	0.066
Arhgef19	Rho guanine nucleotide exchange factor (GEF) 19	0.066
Ctsw	cathepsin W	0.066
Ltbp2	latent transforming growth factor beta binding protein 2	0.066	Mouse
Efna4	ephrin A4	0.066
Slc6a12	solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12	0.066
Zxdb	zinc finger, X-linked, duplicated B	0.066
Tgfb1i1	transforming growth factor beta 1 induced transcript 1	0.065
Cdc42bpb	CDC42 binding protein kinase beta	0.065
Gabbr1	gamma-aminobutyric acid (GABA) B receptor, 1	0.065
Gli2	GLI-Kruppel family member GLI2	0.065
Rgs14	regulator of G-protein signaling 14	0.065
Crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.065
Mst1r	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)	0.065
Bmi1	Bmi1 polycomb ring finger oncogene	0.065
Cadm1	cell adhesion molecule 1	0.065
Plekha5	pleckstrin homology domain containing, family A member 5	0.065
Wwc1	WW, C2 and coiled-coil domain containing 1	0.065
Chmp2b	chromatin modifying protein 2B	0.065