IMP: Integrative Multi-species Prediction

Mus musculus

19 genes annotated in mouse

Multi-species View

regulation of response to oxidative stress

GO:1902882

Any process that modulates the frequency, rate or extent of response to oxidative stress.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouseInclude functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of response to oxidative stress"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "regulation of response to oxidative stress" (in gray)

Name	Description	Probability	Func Analog Organism
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.926
Mapk14	mitogen-activated protein kinase 14	0.893	Fly
Apoe	apolipoprotein E	0.776
Lox	lysyl oxidase	0.704
Bax	BCL2-associated X protein	0.703	Mouse
Trp53	transformation related protein 53	0.688
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.565
Trib3	tribbles homolog 3 (Drosophila)	0.432
Vhl	von Hippel-Lindau tumor suppressor	0.420
Tlr4	toll-like receptor 4	0.418
Prnp	prion protein	0.376
Vegfa	vascular endothelial growth factor A	0.363
Kit	kit oncogene	0.324
Cav1	caveolin 1, caveolae protein	0.312
Bcl2	B-cell leukemia/lymphoma 2	0.283	Mouse
Fbn1	fibrillin 1	0.283
Ldlr	low density lipoprotein receptor	0.245
Pparg	peroxisome proliferator activated receptor gamma	0.244
Ghr	growth hormone receptor	0.237
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.237
Ccl2	chemokine (C-C motif) ligand 2	0.182
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.173
Pten	phosphatase and tensin homolog	0.154
Grb10	growth factor receptor bound protein 10	0.152
Mapkapk2	MAP kinase-activated protein kinase 2	0.151
Stat3	signal transducer and activator of transcription 3	0.142
Mapk11	mitogen-activated protein kinase 11	0.139	Fly
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.119
Aebp1	AE binding protein 1	0.116
Ltbp2	latent transforming growth factor beta binding protein 2	0.114	Mouse
Mfn2	mitofusin 2	0.112
Tgfbr2	transforming growth factor, beta receptor II	0.104
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.103
Mmp2	matrix metallopeptidase 2	0.100	Mouse
Tenc1	tensin like C1 domain-containing phosphatase	0.093
Plxnd1	plexin D1	0.085
Ep300	E1A binding protein p300	0.085
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.083
Bak1	BCL2-antagonist/killer 1	0.081	Mouse
Gab1	growth factor receptor bound protein 2-associated protein 1	0.074
Agtr2	angiotensin II receptor, type 2	0.074
Cryab	crystallin, alpha B	0.073	Mouse
Rps3	ribosomal protein S3	0.071
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.071
Edn1	endothelin 1	0.068
Ctsb	cathepsin B	0.068
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.067
Tlr2	toll-like receptor 2	0.062
Pax3	paired box gene 3	0.062
Cyld	cylindromatosis (turban tumor syndrome)	0.061
Cd44	CD44 antigen	0.059
Ece1	endothelin converting enzyme 1	0.058
Svep1	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1	0.054
Prrx2	paired related homeobox 2	0.054
Mmp9	matrix metallopeptidase 9	0.053	Mouse
Mitf	microphthalmia-associated transcription factor	0.052
Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.051
Lrp1	low density lipoprotein receptor-related protein 1	0.050
Tgfb1	transforming growth factor, beta 1	0.050
Lyst	lysosomal trafficking regulator	0.049
Ccr2	chemokine (C-C motif) receptor 2	0.049
Lipa	lysosomal acid lipase A	0.047
Thbs2	thrombospondin 2	0.046
Aplp2	amyloid beta (A4) precursor-like protein 2	0.046
Gpx1	glutathione peroxidase 1	0.045
Spp1	secreted phosphoprotein 1	0.044
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.044
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.044
Smo	smoothened homolog (Drosophila)	0.044
Irs2	insulin receptor substrate 2	0.044
Ifngr1	interferon gamma receptor 1	0.041
Il6st	interleukin 6 signal transducer	0.041
Fbln1	fibulin 1	0.041	Mouse
Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.040
Fbln5	fibulin 5	0.040
Il6	interleukin 6	0.040
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.040
Mrc2	mannose receptor, C type 2	0.039
Mkl2	MKL/myocardin-like 2	0.039
Sqstm1	sequestosome 1	0.037
Htra3	HtrA serine peptidase 3	0.037
Bag3	BCL2-associated athanogene 3	0.037
Pcolce	procollagen C-endopeptidase enhancer protein	0.037
Mmp11	matrix metallopeptidase 11	0.037	Mouse
Igfbp6	insulin-like growth factor binding protein 6	0.036
Lama5	laminin, alpha 5	0.036
Gaa	glucosidase, alpha, acid	0.036
Mmp8	matrix metallopeptidase 8	0.036	Mouse
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.036
Sftpd	surfactant associated protein D	0.035
Fxyd1	FXYD domain-containing ion transport regulator 1	0.034
Tcn2	transcobalamin 2	0.033
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.033
Emp2	epithelial membrane protein 2	0.033
Plaa	phospholipase A2, activating protein	0.032
C5ar1	complement component 5a receptor 1	0.031
Ptgs2	prostaglandin-endoperoxide synthase 2	0.031
Nbl1	neuroblastoma, suppression of tumorigenicity 1	0.031
Htra1	HtrA serine peptidase 1	0.030
Gpx3	glutathione peroxidase 3	0.029	Mouse
Kif27	kinesin family member 27	0.029
Aifm1	apoptosis-inducing factor, mitochondrion-associated 1	0.029
Sorbs3	sorbin and SH3 domain containing 3	0.028
Dpep1	dipeptidase 1 (renal)	0.028
Idua	iduronidase, alpha-L-	0.028
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.028
Clec4d	C-type lectin domain family 4, member d	0.027
Atf2	activating transcription factor 2	0.026
S1pr2	sphingosine-1-phosphate receptor 2	0.026
Itgb5	integrin beta 5	0.026
Sik3	SIK family kinase 3	0.026
Mcl1	myeloid cell leukemia sequence 1	0.026
Cul7	cullin 7	0.026
Rarb	retinoic acid receptor, beta	0.026
Slc12a4	solute carrier family 12, member 4	0.025
Angptl2	angiopoietin-like 2	0.025
Mknk2	MAP kinase-interacting serine/threonine kinase 2	0.025
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.025
Fpr1	formyl peptide receptor 1	0.025
Srpx	sushi-repeat-containing protein	0.024
Leprel2	leprecan-like 2	0.024
Chi3l1	chitinase 3-like 1	0.024
Mfap5	microfibrillar associated protein 5	0.023
C1qtnf1	C1q and tumor necrosis factor related protein 1	0.023
Ltbp3	latent transforming growth factor beta binding protein 3	0.023	Mouse
Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.023
Tgfb3	transforming growth factor, beta 3	0.023
Loxl1	lysyl oxidase-like 1	0.023
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.022
Vcp	valosin containing protein	0.022
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.022
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.022
Pnpla2	patatin-like phospholipase domain containing 2	0.022
Fas	Fas (TNF receptor superfamily member 6)	0.022
Apbb1	amyloid beta (A4) precursor protein-binding, family B, member 1	0.022
Slc12a6	solute carrier family 12, member 6	0.022
Thbs3	thrombospondin 3	0.022
Foxo1	forkhead box O1	0.021
Msln	mesothelin	0.021
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.021
Timp3	tissue inhibitor of metalloproteinase 3	0.021
Ddr2	discoidin domain receptor family, member 2	0.021
Prdx1	peroxiredoxin 1	0.021
Acvr1	activin A receptor, type 1	0.021
Ptrf	polymerase I and transcript release factor	0.021
Ncoa3	nuclear receptor coactivator 3	0.021
Lamc2	laminin, gamma 2	0.021
Rcn3	reticulocalbin 3, EF-hand calcium binding domain	0.021
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.021
Figf	c-fos induced growth factor	0.020
Sod3	superoxide dismutase 3, extracellular	0.020
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.020
P4ha2	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide	0.020
Kitl	kit ligand	0.020
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.019
Nos3	nitric oxide synthase 3, endothelial cell	0.019
Wisp2	WNT1 inducible signaling pathway protein 2	0.019
S1pr3	sphingosine-1-phosphate receptor 3	0.019
Srpx2	sushi-repeat-containing protein, X-linked 2	0.018
Igf2	insulin-like growth factor 2	0.018
Ccr1	chemokine (C-C motif) receptor 1	0.018
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.018
Agtr1a	angiotensin II receptor, type 1a	0.018
S100a9	S100 calcium binding protein A9 (calgranulin B)	0.017
Snta1	syntrophin, acidic 1	0.017
Il1rn	interleukin 1 receptor antagonist	0.017
Hspb1	heat shock protein 1	0.017
Fzd4	frizzled homolog 4 (Drosophila)	0.017
C3ar1	complement component 3a receptor 1	0.017
Timp2	tissue inhibitor of metalloproteinase 2	0.017
Sva	seminal vesicle antigen	0.017
Ulk4	unc-51-like kinase 4 (C. elegans)	0.017
Ppp1r15a	protein phosphatase 1, regulatory (inhibitor) subunit 15A	0.016
Mt1	metallothionein 1	0.016
Smtn	smoothelin	0.016
Plod3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3	0.016
Tnnc1	troponin C, cardiac/slow skeletal	0.016
Chd2	chromodomain helicase DNA binding protein 2	0.016
Myc	myelocytomatosis oncogene	0.016
Elane	elastase, neutrophil expressed	0.016
Skil	SKI-like	0.016
Rara	retinoic acid receptor, alpha	0.016
Sebox	SEBOX homeobox	0.016
Meig1	meiosis expressed gene 1	0.016
Kcne1	potassium voltage-gated channel, Isk-related subfamily, member 1	0.016
Atp5b	ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit	0.016
Egln1	EGL nine homolog 1 (C. elegans)	0.016
Arpc3	actin related protein 2/3 complex, subunit 3	0.016
Igf2r	insulin-like growth factor 2 receptor	0.016
Tnnt2	troponin T2, cardiac	0.015
Snca	synuclein, alpha	0.015	Human
Trim47	tripartite motif-containing 47	0.015
Hspa5	heat shock protein 5	0.015
Tuba1a	tubulin, alpha 1A	0.015
Cxcr4	chemokine (C-X-C motif) receptor 4	0.015
Prkce	protein kinase C, epsilon	0.015
Mknk1	MAP kinase-interacting serine/threonine kinase 1	0.015
Cdk4	cyclin-dependent kinase 4	0.015
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.015
Gdpd5	glycerophosphodiester phosphodiesterase domain containing 5	0.015
Mfap4	microfibrillar-associated protein 4	0.015
Bcl2l1	BCL2-like 1	0.015	Mouse
Chi3l3	chitinase 3-like 3	0.015
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.015
S100a8	S100 calcium binding protein A8 (calgranulin A)	0.014
Smad1	MAD homolog 1 (Drosophila)	0.014
Ubc	ubiquitin C	0.014
Tnfrsf11b	tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)	0.014
Nphp4	nephronophthisis 4 (juvenile) homolog (human)	0.014
Cd151	CD151 antigen	0.014
Park2	Parkinson disease (autosomal recessive, juvenile) 2, parkin	0.014
Ager	advanced glycosylation end product-specific receptor	0.014
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.014
Nos1	nitric oxide synthase 1, neuronal	0.014
Gnb3	guanine nucleotide binding protein (G protein), beta 3	0.014
Npc1	Niemann Pick type C1	0.014
Hba-a2	hemoglobin alpha, adult chain 2	0.014
Irs1	insulin receptor substrate 1	0.014
Rtn2	reticulon 2 (Z-band associated protein)	0.014
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.014
Flt1	FMS-like tyrosine kinase 1	0.014
Prelp	proline arginine-rich end leucine-rich repeat	0.014
Plcd1	phospholipase C, delta 1	0.014
Tgfbr1	transforming growth factor, beta receptor I	0.014
Il1r1	interleukin 1 receptor, type I	0.014
Tcrd	T-cell receptor delta chain	0.014
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.014
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.014
Fpr2	formyl peptide receptor 2	0.013
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.013
Idh3b	isocitrate dehydrogenase 3 (NAD+) beta	0.013
Epas1	endothelial PAS domain protein 1	0.013
Prl3d1	prolactin family 3, subfamily d, member 1	0.013
Lrp2	low density lipoprotein receptor-related protein 2	0.013
Gsn	gelsolin	0.013
Nos2	nitric oxide synthase 2, inducible	0.013
Htr2b	5-hydroxytryptamine (serotonin) receptor 2B	0.013
Hrh1	histamine receptor H1	0.013
Fstl3	follistatin-like 3	0.013
Fgf7	fibroblast growth factor 7	0.013
Park7	Parkinson disease (autosomal recessive, early onset) 7	0.013
Hoxa3	homeobox A3	0.013
Mmp12	matrix metallopeptidase 12	0.013	Mouse
Ndufv1	NADH dehydrogenase (ubiquinone) flavoprotein 1	0.013
Lonp1	lon peptidase 1, mitochondrial	0.013
Lpl	lipoprotein lipase	0.013
Clu	clusterin	0.013
Calr	calreticulin	0.013
Lepr	leptin receptor	0.013
Alas2	aminolevulinic acid synthase 2, erythroid	0.013
Insr	insulin receptor	0.012	Worm
Bst1	bone marrow stromal cell antigen 1	0.012
Wwtr1	WW domain containing transcription regulator 1	0.012
Ccl7	chemokine (C-C motif) ligand 7	0.012
Saa3	serum amyloid A 3	0.012
Foxi3	forkhead box I3	0.012
Bgn	biglycan	0.012
Itga7	integrin alpha 7	0.012
Mdm2	transformed mouse 3T3 cell double minute 2	0.012
Arhgef7	Rho guanine nucleotide exchange factor (GEF7)	0.012
Tm4sf1	transmembrane 4 superfamily member 1	0.012
Thbd	thrombomodulin	0.012
Fzd1	frizzled homolog 1 (Drosophila)	0.012
Lama4	laminin, alpha 4	0.012
Calca	calcitonin/calcitonin-related polypeptide, alpha	0.012
Npr2	natriuretic peptide receptor 2	0.012
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.011
Dkk3	dickkopf homolog 3 (Xenopus laevis)	0.011
Hip1	huntingtin interacting protein 1	0.011
Casp3	caspase 3	0.011
Tmprss15	transmembrane protease, serine 15	0.011
Mcpt8	mast cell protease 8	0.011
Rc3h1	RING CCCH (C3H) domains 1	0.011
Shc1	src homology 2 domain-containing transforming protein C1	0.011
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.011
Agpat2	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)	0.011
Pygm	muscle glycogen phosphorylase	0.011
Mfap2	microfibrillar-associated protein 2	0.011
Rora	RAR-related orphan receptor alpha	0.011
Surf4	surfeit gene 4	0.011
Rac1	RAS-related C3 botulinum substrate 1	0.011
Slc27a1	solute carrier family 27 (fatty acid transporter), member 1	0.011
Mfrp	membrane-type frizzled-related protein	0.011
Pdgfa	platelet derived growth factor, alpha	0.011
Tbx1	T-box 1	0.011
Tekt1	tektin 1	0.011
Dusp1	dual specificity phosphatase 1	0.011
Cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	0.011
Ngp	neutrophilic granule protein	0.011
Ywhaq	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.011
Cyr61	cysteine rich protein 61	0.011
Hif1an	hypoxia-inducible factor 1, alpha subunit inhibitor	0.011
Mag	myelin-associated glycoprotein	0.011
Il5	interleukin 5	0.011
Fcgr1	Fc receptor, IgG, high affinity I	0.011
Man2c1	mannosidase, alpha, class 2C, member 1	0.010
Lepre1	leprecan 1	0.010
Sp1	trans-acting transcription factor 1	0.010
Serping1	serine (or cysteine) peptidase inhibitor, clade G, member 1	0.010
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.010
Epha2	Eph receptor A2	0.010
Irx3	Iroquois related homeobox 3 (Drosophila)	0.010
Slfn4	schlafen 4	0.010
Scd1	stearoyl-Coenzyme A desaturase 1	0.010
Ppbp	pro-platelet basic protein	0.010
Amelx	amelogenin X chromosome	0.010
Ptgds	prostaglandin D2 synthase (brain)	0.010
Chrnb1	cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)	0.010
Tcrb	T-cell receptor beta chain	0.010