IMP: Integrative Multi-species Prediction

Mus musculus

217 genes annotated in mouse

Multi-species View

positive regulation of apoptotic process

GO:0043065

Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of apoptotic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "positive regulation of apoptotic process" (in gray)

Name	Description	Probability	Func Analog Organism
Trp53	transformation related protein 53	1.000
Pten	phosphatase and tensin homolog	1.000
Tnf	tumor necrosis factor	0.996
Fgfr2	fibroblast growth factor receptor 2	0.993	Mouse
Ctnnb1	catenin (cadherin associated protein), beta 1	0.985	Human
Gli3	GLI-Kruppel family member GLI3	0.985	Worm
Fgfr1	fibroblast growth factor receptor 1	0.984	Mouse
Mapk14	mitogen-activated protein kinase 14	0.983	Mouse
Apc	adenomatosis polyposis coli	0.979
Bcl2	B-cell leukemia/lymphoma 2	0.979	Mouse
Ncoa3	nuclear receptor coactivator 3	0.974	Mouse
Fas	Fas (TNF receptor superfamily member 6)	0.973
Smad3	MAD homolog 3 (Drosophila)	0.972	Human Rat
Tgfb2	transforming growth factor, beta 2	0.967
Tgfb1	transforming growth factor, beta 1	0.965	Mouse Rat
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.961
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.950	Mouse Fly
En1	engrailed 1	0.949
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.949
Lep	leptin	0.948
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.946
Nos2	nitric oxide synthase 2, inducible	0.944	Rat
Shh	sonic hedgehog	0.942
Pax6	paired box gene 6	0.941
Mdm2	transformed mouse 3T3 cell double minute 2	0.940
Alx4	aristaless-like homeobox 4	0.937
Bmp4	bone morphogenetic protein 4	0.936	Human Rat
Fos	FBJ osteosarcoma oncogene	0.935
Cd44	CD44 antigen	0.935
Atm	ataxia telangiectasia mutated homolog (human)	0.925
Runx2	runt related transcription factor 2	0.924	Mouse
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.917
Gli2	GLI-Kruppel family member GLI2	0.916	Worm
Rb1	retinoblastoma 1	0.912
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.904	Mouse
Mapk8	mitogen-activated protein kinase 8	0.901
Neurod1	neurogenic differentiation 1	0.894
Ptgs2	prostaglandin-endoperoxide synthase 2	0.875	Rat
Pparg	peroxisome proliferator activated receptor gamma	0.868	Human Mouse Rat
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.867
Mdm4	transformed mouse 3T3 cell double minute 4	0.867
Hoxd13	homeobox D13	0.859	Mouse
Ren1	renin 1 structural	0.859
Emx1	empty spiracles homolog 1 (Drosophila)	0.859
Jun	Jun oncogene	0.852	Rat
Rara	retinoic acid receptor, alpha	0.851	Mouse
Notch1	Notch gene homolog 1 (Drosophila)	0.827
Lepr	leptin receptor	0.823
Igh	immunoglobulin heavy chain complex	0.812
Hif1a	hypoxia inducible factor 1, alpha subunit	0.805	Rat
Sfrp2	secreted frizzled-related protein 2	0.804	Human Mouse
Notch2	Notch gene homolog 2 (Drosophila)	0.801
App	amyloid beta (A4) precursor protein	0.796
Sox2	SRY-box containing gene 2	0.793
Tgfbr1	transforming growth factor, beta receptor I	0.792	Human Mouse
Foxc1	forkhead box C1	0.790
S1pr2	sphingosine-1-phosphate receptor 2	0.779
Lyz2	lysozyme 2	0.768
Fshr	follicle stimulating hormone receptor	0.767
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.763
E2f1	E2F transcription factor 1	0.761	Fly
Klf4	Kruppel-like factor 4 (gut)	0.757
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.756	Mouse
Mef2d	myocyte enhancer factor 2D	0.751	Mouse
Nf1	neurofibromatosis 1	0.750
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.736
Rarg	retinoic acid receptor, gamma	0.732
Gdnf	glial cell line derived neurotrophic factor	0.732
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.730
Kit	kit oncogene	0.723
Csf1	colony stimulating factor 1 (macrophage)	0.718
Pkd1	polycystic kidney disease 1 homolog	0.712
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.709
Nos3	nitric oxide synthase 3, endothelial cell	0.706	Rat
Jak2	Janus kinase 2	0.706
Lef1	lymphoid enhancer binding factor 1	0.705	Mouse
Otx2	orthodenticle homolog 2 (Drosophila)	0.704
Mcl1	myeloid cell leukemia sequence 1	0.702
Rxra	retinoid X receptor alpha	0.702	Rat
Zeb1	zinc finger E-box binding homeobox 1	0.700
Egr1	early growth response 1	0.700	Rat
Traf6	TNF receptor-associated factor 6	0.699
Wnt6	wingless-related MMTV integration site 6	0.699	Mouse
Vegfa	vascular endothelial growth factor A	0.691
Foxf1a	forkhead box F1a	0.686
Gsk3b	glycogen synthase kinase 3 beta	0.686
Smad7	MAD homolog 7 (Drosophila)	0.679
Prrx1	paired related homeobox 1	0.679
Zfp36	zinc finger protein 36	0.678
Prrx2	paired related homeobox 2	0.672
Ar	androgen receptor	0.670
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.662
Prlr	prolactin receptor	0.662
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.660
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.660
Adam9	a disintegrin and metallopeptidase domain 9 (meltrin gamma)	0.657	Mouse
Lrrk2	leucine-rich repeat kinase 2	0.655
Egfr	epidermal growth factor receptor	0.650
Ptch1	patched homolog 1	0.649
Drd2	dopamine receptor D2	0.649
Dok1	docking protein 1	0.647
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.642	Human
Ccl2	chemokine (C-C motif) ligand 2	0.638
Tgfbr2	transforming growth factor, beta receptor II	0.637	Mouse
Il10	interleukin 10	0.636	Mouse
Dusp1	dual specificity phosphatase 1	0.636
Thrb	thyroid hormone receptor beta	0.636	Mouse
Cxcl2	chemokine (C-X-C motif) ligand 2	0.635
Cd40	CD40 antigen	0.632	Human
Msh2	mutS homolog 2 (E. coli)	0.632
Casp8	caspase 8	0.626
Socs1	suppressor of cytokine signaling 1	0.626
Gata4	GATA binding protein 4	0.621
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.619
Mef2c	myocyte enhancer factor 2C	0.614
Acvr1	activin A receptor, type 1	0.609	Mouse
Skil	SKI-like	0.607
Vhl	von Hippel-Lindau tumor suppressor	0.600
Anxa3	annexin A3	0.599	Mouse
Nfatc3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	0.598	Mouse
Id1	inhibitor of DNA binding 1	0.597
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.588	Mouse
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.586
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.586
Axin1	axin 1	0.585
Hand1	heart and neural crest derivatives expressed transcript 1	0.580	Mouse
Twist1	twist homolog 1 (Drosophila)	0.577	Mouse
Sox9	SRY-box containing gene 9	0.574
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.573
Klf6	Kruppel-like factor 6	0.565
Il1b	interleukin 1 beta	0.555
Ptch2	patched homolog 2	0.555
Sin3a	transcriptional regulator, SIN3A (yeast)	0.551
Pofut1	protein O-fucosyltransferase 1	0.544
Ahr	aryl-hydrocarbon receptor	0.543
Vdr	vitamin D receptor	0.540
Nptn	neuroplastin	0.539
Stat3	signal transducer and activator of transcription 3	0.534	Mouse
Foxd2	forkhead box D2	0.529
S100a8	S100 calcium binding protein A8 (calgranulin A)	0.527	Human
Cbl	Casitas B-lineage lymphoma	0.525
Cd81	CD81 antigen	0.518
Sfrp1	secreted frizzled-related protein 1	0.516
Gdf5	growth differentiation factor 5	0.513	Mouse
Adrb3	adrenergic receptor, beta 3	0.512
Hdac1	histone deacetylase 1	0.510	Rat
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.510
Stat5a	signal transducer and activator of transcription 5A	0.509	Mouse
Pax2	paired box gene 2	0.509
Pax8	paired box gene 8	0.505
Cxcl13	chemokine (C-X-C motif) ligand 13	0.503
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.502	Rat
Ep300	E1A binding protein p300	0.501
Ccr1	chemokine (C-C motif) receptor 1	0.500
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.499
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.498
Stat5b	signal transducer and activator of transcription 5B	0.495	Mouse
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.494
Casp1	caspase 1	0.492	Mouse Rat Fly
Apaf1	apoptotic peptidase activating factor 1	0.490
Tbx15	T-box 15	0.489
Wisp2	WNT1 inducible signaling pathway protein 2	0.488	Mouse
Fst	follistatin	0.488
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.484
Emx2	empty spiracles homolog 2 (Drosophila)	0.475
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.474
Nptx1	neuronal pentraxin 1	0.468
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.468
Numb	numb gene homolog (Drosophila)	0.463
Selp	selectin, platelet	0.462
Irf1	interferon regulatory factor 1	0.461
S100a9	S100 calcium binding protein A9 (calgranulin B)	0.459	Human
Hdac7	histone deacetylase 7	0.459
Myod1	myogenic differentiation 1	0.457
Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	0.457
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.454
Ctsk	cathepsin K	0.450
Meox2	mesenchyme homeobox 2	0.449
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.448
Sox11	SRY-box containing gene 11	0.447
Rock2	Rho-associated coiled-coil containing protein kinase 2	0.444
Stk4	serine/threonine kinase 4	0.442
Thra	thyroid hormone receptor alpha	0.441	Mouse
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.440
Ifngr1	interferon gamma receptor 1	0.440
Slfn4	schlafen 4	0.439
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.434	Mouse
Il6st	interleukin 6 signal transducer	0.430
Wt1	Wilms tumor 1 homolog	0.430	Human
Gas1	growth arrest specific 1	0.427
Ywhaq	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.427
Ch25h	cholesterol 25-hydroxylase	0.425
Il1r1	interleukin 1 receptor, type I	0.425
Isl1	ISL1 transcription factor, LIM/homeodomain	0.422
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.419
Stk3	serine/threonine kinase 3 (Ste20, yeast homolog)	0.418
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.415
Meox1	mesenchyme homeobox 1	0.415
Alx3	aristaless-like homeobox 3	0.414
Brca1	breast cancer 1	0.412
Rbl1	retinoblastoma-like 1 (p107)	0.412
Ccl22	chemokine (C-C motif) ligand 22	0.411
Lhx1	LIM homeobox protein 1	0.411
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.411
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.410
Pgr	progesterone receptor	0.405	Mouse
Sertad1	SERTA domain containing 1	0.403
Lrp5	low density lipoprotein receptor-related protein 5	0.401	Mouse
Vcl	vinculin	0.400	Mouse
Atf3	activating transcription factor 3	0.398
Dlx5	distal-less homeobox 5	0.397
Bdkrb2	bradykinin receptor, beta 2	0.396
Daxx	Fas death domain-associated protein	0.395
Ntf3	neurotrophin 3	0.395
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.395
Adam12	a disintegrin and metallopeptidase domain 12 (meltrin alpha)	0.394	Mouse
Tlr4	toll-like receptor 4	0.393	Rat
Ikbkg	inhibitor of kappaB kinase gamma	0.393
Agtr1a	angiotensin II receptor, type 1a	0.392
Wnt3a	wingless-related MMTV integration site 3A	0.391
Hoxa2	homeobox A2	0.388
Mst1r	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)	0.388
C3ar1	complement component 3a receptor 1	0.387
Il4ra	interleukin 4 receptor, alpha	0.387
Tcf15	transcription factor 15	0.385	Mouse
Atf2	activating transcription factor 2	0.385
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.385	Mouse
Lrp1	low density lipoprotein receptor-related protein 1	0.384	Mouse
Pdcd6ip	programmed cell death 6 interacting protein	0.383
Ppp2ca	protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform	0.382	Rat
Snai1	snail homolog 1 (Drosophila)	0.382
Epha4	Eph receptor A4	0.380	Mouse
Nog	noggin	0.378
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.377	Mouse
Neurog3	neurogenin 3	0.377	Mouse
Prkce	protein kinase C, epsilon	0.377
Ephb2	Eph receptor B2	0.376	Mouse
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.376
Huwe1	HECT, UBA and WWE domain containing 1	0.375
Wnt10b	wingless related MMTV integration site 10b	0.374	Mouse
Ctsl	cathepsin L	0.374
Fadd	Fas (TNFRSF6)-associated via death domain	0.371
Socs3	suppressor of cytokine signaling 3	0.371
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.369
Dkc1	dyskeratosis congenita 1, dyskerin homolog (human)	0.369
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.367
Smo	smoothened homolog (Drosophila)	0.366
Il10ra	interleukin 10 receptor, alpha	0.365
Mb	myoglobin	0.363
Atp5b	ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit	0.362
Cdk2	cyclin-dependent kinase 2	0.362
Kiss1	KiSS-1 metastasis-suppressor	0.362
Tnfrsf11b	tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)	0.362
Esr2	estrogen receptor 2 (beta)	0.360	Rat
Hspa8	heat shock protein 8	0.358
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.355	Mouse
Foxo1	forkhead box O1	0.354	Human Worm
Hoxc9	homeobox C9	0.353
Dok2	docking protein 2	0.352
Id2	inhibitor of DNA binding 2	0.351
Clec4d	C-type lectin domain family 4, member d	0.351
Chrng	cholinergic receptor, nicotinic, gamma polypeptide	0.351
Bmp7	bone morphogenetic protein 7	0.350
Jak3	Janus kinase 3	0.349
Dnm1	dynamin 1	0.349
Shc1	src homology 2 domain-containing transforming protein C1	0.349
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.347
Wwox	WW domain-containing oxidoreductase	0.346
Chuk	conserved helix-loop-helix ubiquitous kinase	0.346
Dffb	DNA fragmentation factor, beta subunit	0.345
Fcgr1	Fc receptor, IgG, high affinity I	0.345
Ddah2	dimethylarginine dimethylaminohydrolase 2	0.345
Ccl7	chemokine (C-C motif) ligand 7	0.343	Mouse
Fosb	FBJ osteosarcoma oncogene B	0.342
Ikbkb	inhibitor of kappaB kinase beta	0.342
Ltb	lymphotoxin B	0.340
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.338	Mouse
Anxa1	annexin A1	0.338
Dhx15	DEAH (Asp-Glu-Ala-His) box polypeptide 15	0.338
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.337	Mouse
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.336
Esr1	estrogen receptor 1 (alpha)	0.335
Hspa5	heat shock protein 5	0.335
Amhr2	anti-Mullerian hormone type 2 receptor	0.334	Mouse
Tg	thyroglobulin	0.332
Htra3	HtrA serine peptidase 3	0.331	Mouse Fly
Plin1	perilipin 1	0.330
Dab1	disabled homolog 1 (Drosophila)	0.330
Cd2ap	CD2-associated protein	0.330
Bmp5	bone morphogenetic protein 5	0.329	Mouse
Hoxa5	homeobox A5	0.329	Human
Sh2d2a	SH2 domain protein 2A	0.329
Stub1	STIP1 homology and U-Box containing protein 1	0.327
Cyr61	cysteine rich protein 61	0.326
Lif	leukemia inhibitory factor	0.325
Gal	galanin	0.324	Rat
Oprm1	opioid receptor, mu 1	0.320
Neurog2	neurogenin 2	0.320	Mouse
Tcf7	transcription factor 7, T-cell specific	0.320	Mouse
Chrm1	cholinergic receptor, muscarinic 1, CNS	0.320
Fbxw7	F-box and WD-40 domain protein 7	0.319
Angptl2	angiopoietin-like 2	0.319
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.315	Human
Spnb2	spectrin beta 2	0.312
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.312
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.310
Grb2	growth factor receptor bound protein 2	0.310
Rbl2	retinoblastoma-like 2	0.310
Gata6	GATA binding protein 6	0.308
Suz12	suppressor of zeste 12 homolog (Drosophila)	0.308
Glis2	GLIS family zinc finger 2	0.307	Worm
Hdac4	histone deacetylase 4	0.307	Rat
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.306	Mouse
Mfn2	mitofusin 2	0.305
Bnc1	basonuclin 1	0.305
Brca2	breast cancer 2	0.305
Psen1	presenilin 1	0.304
Btg2	B-cell translocation gene 2, anti-proliferative	0.304
Fut7	fucosyltransferase 7	0.304
Arhgap1	Rho GTPase activating protein 1	0.303
Ptf1a	pancreas specific transcription factor, 1a	0.303	Mouse
Foxc2	forkhead box C2	0.303
Fgfr4	fibroblast growth factor receptor 4	0.301	Mouse
Xiap	X-linked inhibitor of apoptosis	0.299
Mknk2	MAP kinase-interacting serine/threonine kinase 2	0.297
Ptprs	protein tyrosine phosphatase, receptor type, S	0.297
Pbx1	pre B-cell leukemia transcription factor 1	0.296
Hr	hairless	0.296
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.295
Cd14	CD14 antigen	0.295
Trp73	transformation related protein 73	0.294
Bmp2	bone morphogenetic protein 2	0.294	Human
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.293
Wnt3	wingless-related MMTV integration site 3	0.292	Mouse
Sox3	SRY-box containing gene 3	0.291
Mib1	mindbomb homolog 1 (Drosophila)	0.290
Hoxa11	homeobox A11	0.290
Eda	ectodysplasin-A	0.289
Igbp1	immunoglobulin (CD79A) binding protein 1	0.288
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.288
Anxa5	annexin A5	0.287	Mouse
Trib3	tribbles homolog 3 (Drosophila)	0.286
Nfatc4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	0.285
Prkcc	protein kinase C, gamma	0.285	Mouse
Lmna	lamin A	0.284
Htt	huntingtin	0.283
Hoxc6	homeobox C6	0.283
Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3	0.282
Dlg4	discs, large homolog 4 (Drosophila)	0.280
Insm1	insulinoma-associated 1	0.276
Ccl8	chemokine (C-C motif) ligand 8	0.275
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.275
Ret	ret proto-oncogene	0.274	Human
Wls	wntless homolog (Drosophila)	0.273
Cdk4	cyclin-dependent kinase 4	0.272
Dysf	dysferlin	0.272
Fes	feline sarcoma oncogene	0.270
Bmper	BMP-binding endothelial regulator	0.269
Hivep2	human immunodeficiency virus type I enhancer binding protein 2	0.269
S100a10	S100 calcium binding protein A10 (calpactin)	0.265
Sp1	trans-acting transcription factor 1	0.265
Ccnd1	cyclin D1	0.265
Ate1	arginyltransferase 1	0.264
Pml	promyelocytic leukemia	0.264
Ltbp3	latent transforming growth factor beta binding protein 3	0.264
Cd47	CD47 antigen (Rh-related antigen, integrin-associated signal transducer)	0.263
Fosl2	fos-like antigen 2	0.263
Dll4	delta-like 4 (Drosophila)	0.263
Onecut1	one cut domain, family member 1	0.262
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.261
Hes1	hairy and enhancer of split 1 (Drosophila)	0.260
BC021891	cDNA sequence BC021891	0.260
Efna4	ephrin A4	0.259
Fmn1	formin 1	0.259
Rnf8	ring finger protein 8	0.258
Cd9	CD9 antigen	0.257
Sat1	spermidine/spermine N1-acetyl transferase 1	0.256
Stat6	signal transducer and activator of transcription 6	0.255	Mouse
Tbx2	T-box 2	0.254
Efnb2	ephrin B2	0.253
Nlrp3	NLR family, pyrin domain containing 3	0.253
Tcf3	transcription factor 3	0.252
Ccne2	cyclin E2	0.251	Fly
Fzd4	frizzled homolog 4 (Drosophila)	0.250
Notch4	Notch gene homolog 4 (Drosophila)	0.249	Mouse
Fgf5	fibroblast growth factor 5	0.249
Osmr	oncostatin M receptor	0.248
Stim2	stromal interaction molecule 2	0.248
Wdr26	WD repeat domain 26	0.248
Hic1	hypermethylated in cancer 1	0.247
Cdkn2d	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	0.247
Arap3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.247
Cyp1b1	cytochrome P450, family 1, subfamily b, polypeptide 1	0.247
Tgfa	transforming growth factor alpha	0.246
Pitx2	paired-like homeodomain transcription factor 2	0.246
Zfp651	zinc finger protein 651	0.246
Msln	mesothelin	0.246
Birc3	baculoviral IAP repeat-containing 3	0.246
Gpr132	G protein-coupled receptor 132	0.245
Rhbdl3	rhomboid, veinlet-like 3 (Drosophila)	0.244
Amotl2	angiomotin-like 2	0.243
Gadd45a	growth arrest and DNA-damage-inducible 45 alpha	0.243	Human
Ggt5	gamma-glutamyltransferase 5	0.243
Slit3	slit homolog 3 (Drosophila)	0.243
Blnk	B-cell linker	0.243
Sufu	suppressor of fused homolog (Drosophila)	0.242
Tcf21	transcription factor 21	0.242
Tph1	tryptophan hydroxylase 1	0.241
Fgf2	fibroblast growth factor 2	0.240
Epha1	Eph receptor A1	0.240	Mouse
St8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.240
Add1	adducin 1 (alpha)	0.240
Zfp36l1	zinc finger protein 36, C3H type-like 1	0.239
Pax9	paired box gene 9	0.239
Grem1	gremlin 1	0.239
Lhx3	LIM homeobox protein 3	0.238
Pstpip1	proline-serine-threonine phosphatase-interacting protein 1	0.237
Pxn	paxillin	0.237
Pnpla2	patatin-like phospholipase domain containing 2	0.235
Rac1	RAS-related C3 botulinum substrate 1	0.235
Tmeff2	transmembrane protein with EGF-like and two follistatin-like domains 2	0.235
Rem1	rad and gem related GTP binding protein 1	0.235
Col2a1	collagen, type II, alpha 1	0.234
Il27ra	interleukin 27 receptor, alpha	0.233
Mef2a	myocyte enhancer factor 2A	0.233	Mouse
Rora	RAR-related orphan receptor alpha	0.232
Arx	aristaless related homeobox	0.232
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.232
Hoxd11	homeobox D11	0.230
Slfn2	schlafen 2	0.229
Ephb3	Eph receptor B3	0.229	Mouse
Kcnj4	potassium inwardly-rectifying channel, subfamily J, member 4	0.228
Rin2	Ras and Rab interactor 2	0.228
Ednra	endothelin receptor type A	0.227
Stab1	stabilin 1	0.227
Adam17	a disintegrin and metallopeptidase domain 17	0.226	Mouse
Hoxc5	homeobox C5	0.226
Npr3	natriuretic peptide receptor 3	0.225
Hoxa13	homeobox A13	0.225
Junb	Jun-B oncogene	0.224
Bcl2l10	Bcl2-like 10	0.224
Ppef2	protein phosphatase, EF hand calcium-binding domain 2	0.222
Emid2	EMI domain containing 2	0.221
Serpina3c	serine (or cysteine) peptidase inhibitor, clade A, member 3C	0.221	Rat
Il5	interleukin 5	0.221
Bcl2l1	BCL2-like 1	0.221
Dmbx1	diencephalon/mesencephalon homeobox 1	0.221
Fzd2	frizzled homolog 2 (Drosophila)	0.220
Ccl6	chemokine (C-C motif) ligand 6	0.220	Mouse
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.220
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.220
Cdx1	caudal type homeobox 1	0.219
Bax	BCL2-associated X protein	0.217
Errfi1	ERBB receptor feedback inhibitor 1	0.216
Jarid2	jumonji, AT rich interactive domain 2	0.216
Shox2	short stature homeobox 2	0.215
Sox4	SRY-box containing gene 4	0.214	Human
Wnt7a	wingless-related MMTV integration site 7A	0.213	Mouse
Hsp90aa1	heat shock protein 90, alpha (cytosolic), class A member 1	0.213
Coro1b	coronin, actin binding protein 1B	0.213
Tert	telomerase reverse transcriptase	0.212
Nynrin	NYN domain and retroviral integrase containing	0.212
Leprel2	leprecan-like 2	0.211
Sh3rf1	SH3 domain containing ring finger 1	0.211
Fndc7	fibronectin type III domain containing 7	0.211
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.210
Gna11	guanine nucleotide binding protein, alpha 11	0.210
Plin4	perilipin 4	0.210
Cdc42ep1	CDC42 effector protein (Rho GTPase binding) 1	0.210
Dtx1	deltex 1 homolog (Drosophila)	0.209
Prkcd	protein kinase C, delta	0.209
Mcoln2	mucolipin 2	0.209
Efs	embryonal Fyn-associated substrate	0.208
Ikzf1	IKAROS family zinc finger 1	0.207
Pax3	paired box gene 3	0.207
Fgf15	fibroblast growth factor 15	0.206
Smad6	MAD homolog 6 (Drosophila)	0.205
Msx1	homeobox, msh-like 1	0.205
Cxcr4	chemokine (C-X-C motif) receptor 4	0.204
Ccl4	chemokine (C-C motif) ligand 4	0.203	Mouse
Anxa4	annexin A4	0.203	Mouse
Il2rb	interleukin 2 receptor, beta chain	0.203
Gcm2	glial cells missing homolog 2 (Drosophila)	0.203
Kif5b	kinesin family member 5B	0.201
Jag2	jagged 2	0.201
Acd	adrenocortical dysplasia	0.201
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.201
Pnoc	prepronociceptin	0.201
Col4a4	collagen, type IV, alpha 4	0.200
Nupr1	nuclear protein 1	0.199
Ldb3	LIM domain binding 3	0.199
Fzd1	frizzled homolog 1 (Drosophila)	0.199
Ctnna1	catenin (cadherin associated protein), alpha 1	0.199
Arhgap4	Rho GTPase activating protein 4	0.198
Prkaca	protein kinase, cAMP dependent, catalytic, alpha	0.198
Gpc3	glypican 3	0.197
Saa3	serum amyloid A 3	0.197
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.197
Fzd7	frizzled homolog 7 (Drosophila)	0.197
Mapkapk2	MAP kinase-activated protein kinase 2	0.196
Hp	haptoglobin	0.196
Rdh10	retinol dehydrogenase 10 (all-trans)	0.196
Cycs	cytochrome c, somatic	0.196
Avpr2	arginine vasopressin receptor 2	0.196
Spdef	SAM pointed domain containing ets transcription factor	0.196	Human
Myc	myelocytomatosis oncogene	0.196
Nedd9	neural precursor cell expressed, developmentally down-regulated gene 9	0.195
Cidec	cell death-inducing DFFA-like effector c	0.195
Ptx3	pentraxin related gene	0.195
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.195
Cast	calpastatin	0.194
Neurog1	neurogenin 1	0.194	Mouse
Plxnd1	plexin D1	0.193
Prss39	protease, serine, 39	0.193
Hif3a	hypoxia inducible factor 3, alpha subunit	0.193
Aff1	AF4/FMR2 family, member 1	0.192
Tal2	T-cell acute lymphocytic leukemia 2	0.192	Mouse
Foxa2	forkhead box A2	0.192
Asxl1	additional sex combs like 1 (Drosophila)	0.191
Bik	BCL2-interacting killer	0.191
Gja3	gap junction protein, alpha 3	0.190
Uba7	ubiquitin-like modifier activating enzyme 7	0.190
Fmnl1	formin-like 1	0.189
Fgf4	fibroblast growth factor 4	0.188
Robo3	roundabout homolog 3 (Drosophila)	0.188
Lrp4	low density lipoprotein receptor-related protein 4	0.188	Mouse
Rhob	ras homolog gene family, member B	0.186	Human
S1pr3	sphingosine-1-phosphate receptor 3	0.186
Msx3	homeobox, msh-like 3	0.185	Mouse
Dck	deoxycytidine kinase	0.185
P2ry2	purinergic receptor P2Y, G-protein coupled 2	0.185
Hlx	H2.0-like homeobox	0.184
Grin2a	glutamate receptor, ionotropic, NMDA2A (epsilon 1)	0.184
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.184
Mycl1	v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)	0.184	Mouse
Sesn1	sestrin 1	0.184
Stag1	stromal antigen 1	0.183
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.183
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.183
Gata3	GATA binding protein 3	0.182
Gtf2ird1	general transcription factor II I repeat domain-containing 1	0.182
Usp9x	ubiquitin specific peptidase 9, X chromosome	0.182
Atoh1	atonal homolog 1 (Drosophila)	0.181	Mouse
Map2k7	mitogen-activated protein kinase kinase 7	0.181	Rat
Wnt2b	wingless related MMTV integration site 2b	0.180	Mouse
Chd2	chromodomain helicase DNA binding protein 2	0.179
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.179
Ccr3	chemokine (C-C motif) receptor 3	0.178
Alx1	ALX homeobox 1	0.178
Ccr7	chemokine (C-C motif) receptor 7	0.178
Ilk	integrin linked kinase	0.178
Bbc3	BCL2 binding component 3	0.177
Gpr50	G-protein-coupled receptor 50	0.177
Mfap2	microfibrillar-associated protein 2	0.177
Mapk3	mitogen-activated protein kinase 3	0.177
Mybph	myosin binding protein H	0.176
Fjx1	four jointed box 1 (Drosophila)	0.176
Adra1a	adrenergic receptor, alpha 1a	0.175
Wrn	Werner syndrome homolog (human)	0.175
Rassf1	Ras association (RalGDS/AF-6) domain family member 1	0.175
Tgfbr3	transforming growth factor, beta receptor III	0.175
Npm1	nucleophosmin 1	0.174
Runx1t1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.174
Mpp3	membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)	0.173
C1qtnf1	C1q and tumor necrosis factor related protein 1	0.173
Procr	protein C receptor, endothelial	0.172
Tiparp	TCDD-inducible poly(ADP-ribose) polymerase	0.172
Cct2	chaperonin containing Tcp1, subunit 2 (beta)	0.172
Yap1	yes-associated protein 1	0.171
Endou	endonuclease, polyU-specific	0.171
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.170
Itgal	integrin alpha L	0.170
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.170
Gata5	GATA binding protein 5	0.169
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.169
Tmbim1	transmembrane BAX inhibitor motif containing 1	0.169
Gsn	gelsolin	0.169
P4ha1	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide	0.169
Bcl6b	B-cell CLL/lymphoma 6, member B	0.169
Rpl24	ribosomal protein L24	0.169
Egr2	early growth response 2	0.169
Nobox	NOBOX oogenesis homeobox	0.168
Irf9	interferon regulatory factor 9	0.168
Thbs1	thrombospondin 1	0.167	Human
Apobec1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	0.167
Aldh1a1	aldehyde dehydrogenase family 1, subfamily A1	0.167
Entpd2	ectonucleoside triphosphate diphosphohydrolase 2	0.167
Adam8	a disintegrin and metallopeptidase domain 8	0.167
Sod1	superoxide dismutase 1, soluble	0.167
Ncoa1	nuclear receptor coactivator 1	0.166
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.166
Dab2	disabled homolog 2 (Drosophila)	0.166
Rel	reticuloendotheliosis oncogene	0.165
Mapk1	mitogen-activated protein kinase 1	0.165
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.165
Pcsk1	proprotein convertase subtilisin/kexin type 1	0.165
Foxo3	forkhead box O3	0.165	Human Worm
Lilrb3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.164
Nhedc2	Na+/H+ exchanger domain containing 2	0.163
Timp3	tissue inhibitor of metalloproteinase 3	0.163
Adam11	a disintegrin and metallopeptidase domain 11	0.163	Mouse
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.162
Kif5c	kinesin family member 5C	0.162
Bdkrb1	bradykinin receptor, beta 1	0.162
Fgf7	fibroblast growth factor 7	0.162
Ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.161
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.161	Mouse
Plxna3	plexin A3	0.161
Aip	aryl-hydrocarbon receptor-interacting protein	0.160
Foxf2	forkhead box F2	0.160
Mab21l2	mab-21-like 2 (C. elegans)	0.160
Nkx2-1	NK2 homeobox 1	0.160
Nat3	N-acetyltransferase 3	0.160
Gpd2	glycerol phosphate dehydrogenase 2, mitochondrial	0.160
Prph	peripherin	0.159
Capn2	calpain 2	0.159	Mouse
Btbd17	BTB (POZ) domain containing 17	0.159
Pdx1	pancreatic and duodenal homeobox 1	0.159
Bmp1	bone morphogenetic protein 1	0.159
Thbd	thrombomodulin	0.158	Mouse
Lgals3	lectin, galactose binding, soluble 3	0.158
Ppp3r1	protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)	0.158
Qk	quaking	0.158
Madcam1	mucosal vascular addressin cell adhesion molecule 1	0.157
Rab3il1	RAB3A interacting protein (rabin3)-like 1	0.157
Col13a1	collagen, type XIII, alpha 1	0.157
Mecom	MDS1 and EVI1 complex locus	0.157
Ets1	E26 avian leukemia oncogene 1, 5' domain	0.156
Eya4	eyes absent 4 homolog (Drosophila)	0.156
Nes	nestin	0.155
Foxk1	forkhead box K1	0.155
Ppp2r2a	protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform	0.155
Traf3	TNF receptor-associated factor 3	0.155
Fzd6	frizzled homolog 6 (Drosophila)	0.155
Fyn	Fyn proto-oncogene	0.155	Mouse
Pax1	paired box gene 1	0.155
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.155
Plcg1	phospholipase C, gamma 1	0.154
Mfsd4	major facilitator superfamily domain containing 4	0.154
Cxcl1	chemokine (C-X-C motif) ligand 1	0.154
Fzd8	frizzled homolog 8 (Drosophila)	0.154
Cdkn1c	cyclin-dependent kinase inhibitor 1C (P57)	0.154
Cpe	carboxypeptidase E	0.153
Terf1	telomeric repeat binding factor 1	0.153	Human
Chl1	cell adhesion molecule with homology to L1CAM	0.153
Cyld	cylindromatosis (turban tumor syndrome)	0.152	Human
Msr1	macrophage scavenger receptor 1	0.152
Has1	hyaluronan synthase1	0.152
Phf19	PHD finger protein 19	0.152
Timm23	translocase of inner mitochondrial membrane 23 homolog (yeast)	0.152
Pgk1	phosphoglycerate kinase 1	0.152
Robo2	roundabout homolog 2 (Drosophila)	0.152
Xcl1	chemokine (C motif) ligand 1	0.152	Mouse
Wnt9a	wingless-type MMTV integration site 9A	0.151	Mouse
Prkd2	protein kinase D2	0.151
Phox2a	paired-like homeobox 2a	0.151
Ctdsp1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1	0.151
Gja1	gap junction protein, alpha 1	0.151
Sdf2l1	stromal cell-derived factor 2-like 1	0.151
Cuzd1	CUB and zona pellucida-like domains 1	0.151
Crb2	crumbs homolog 2 (Drosophila)	0.151
Hsp90b1	heat shock protein 90, beta (Grp94), member 1	0.151
Tpi1	triosephosphate isomerase 1	0.150
Barx1	BarH-like homeobox 1	0.150
Krt71	keratin 71	0.150
Braf	Braf transforming gene	0.149
Dll1	delta-like 1 (Drosophila)	0.149
Tax1bp3	Tax1 (human T-cell leukemia virus type I) binding protein 3	0.149
Ccrl2	chemokine (C-C motif) receptor-like 2	0.148
Cdk14	cyclin-dependent kinase 14	0.148
Tomm20	translocase of outer mitochondrial membrane 20 homolog (yeast)	0.148
Ier3	immediate early response 3	0.148
Crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.148
Folr2	folate receptor 2 (fetal)	0.148
Fasl	Fas ligand (TNF superfamily, member 6)	0.148	Human Mouse Rat
Calb2	calbindin 2	0.148
Pthlh	parathyroid hormone-like peptide	0.148
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.148
Cct6a	chaperonin containing Tcp1, subunit 6a (zeta)	0.148
Gad2	glutamic acid decarboxylase 2	0.147
Maff	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)	0.147
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.147
Gapdh	glyceraldehyde-3-phosphate dehydrogenase	0.147
Hipk3	homeodomain interacting protein kinase 3	0.147
Rnf31	ring finger protein 31	0.147
Zan	zonadhesin	0.147	Mouse
Pea15a	phosphoprotein enriched in astrocytes 15A	0.147
Ccl12	chemokine (C-C motif) ligand 12	0.146	Mouse
Mybl2	myeloblastosis oncogene-like 2	0.146
Thbs2	thrombospondin 2	0.146
Aldoa	aldolase A, fructose-bisphosphate	0.146
Wnt7b	wingless-related MMTV integration site 7B	0.146	Mouse
Lrp6	low density lipoprotein receptor-related protein 6	0.146
Gdf9	growth differentiation factor 9	0.146
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.145
Hdac5	histone deacetylase 5	0.145
Akp3	alkaline phosphatase 3, intestine, not Mn requiring	0.145
Cst3	cystatin C	0.145
Stk11	serine/threonine kinase 11	0.145	Fly
Odz4	odd Oz/ten-m homolog 4 (Drosophila)	0.144
Lag3	lymphocyte-activation gene 3	0.144
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.144
Sox13	SRY-box containing gene 13	0.144
F3	coagulation factor III	0.143	Human
Nucks1	nuclear casein kinase and cyclin-dependent kinase substrate 1	0.143
5430421N21Rik	RIKEN cDNA 5430421N21 gene	0.143
Pkm2	pyruvate kinase, muscle	0.143
Slc27a1	solute carrier family 27 (fatty acid transporter), member 1	0.143
Hoxa10	homeobox A10	0.143
Calca	calcitonin/calcitonin-related polypeptide, alpha	0.142
Rarb	retinoic acid receptor, beta	0.142
Dbn1	drebrin 1	0.142
Bmi1	Bmi1 polycomb ring finger oncogene	0.142
Mmp9	matrix metallopeptidase 9	0.142
Ifitm6	interferon induced transmembrane protein 6	0.142
Tenc1	tensin like C1 domain-containing phosphatase	0.142
Slc16a2	solute carrier family 16 (monocarboxylic acid transporters), member 2	0.142
Hoxb4	homeobox B4	0.141	Fly
Dcc	deleted in colorectal carcinoma	0.141
Map3k5	mitogen-activated protein kinase kinase kinase 5	0.141
Vav2	vav 2 oncogene	0.140
0610031J06Rik	RIKEN cDNA 0610031J06 gene	0.140
Hoxd12	homeobox D12	0.140	Fly
Slc40a1	solute carrier family 40 (iron-regulated transporter), member 1	0.140
AY074887	cDNA sequence AY074887	0.139
Epas1	endothelial PAS domain protein 1	0.139
Cbfa2t3	core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)	0.138
Plcb3	phospholipase C, beta 3	0.137
Camk2b	calcium/calmodulin-dependent protein kinase II, beta	0.137
Trpv1	transient receptor potential cation channel, subfamily V, member 1	0.137	Rat
Ier2	immediate early response 2	0.137
Itgb5	integrin beta 5	0.137
Pygb	brain glycogen phosphorylase	0.137
Ucp3	uncoupling protein 3 (mitochondrial, proton carrier)	0.136
Tab1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.136
S100a6	S100 calcium binding protein A6 (calcyclin)	0.136
Plaur	plasminogen activator, urokinase receptor	0.136
Ehf	ets homologous factor	0.135
Capza3	capping protein (actin filament) muscle Z-line, alpha 3	0.135
Was	Wiskott-Aldrich syndrome homolog (human)	0.135
Gsc	goosecoid homeobox	0.135
Smarcd1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.135
Adrb2	adrenergic receptor, beta 2	0.135	Rat
Efna5	ephrin A5	0.134
Mtap7d1	microtubule-associated protein 7 domain containing 1	0.134
Nfatc1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.134	Mouse
Masp1	mannan-binding lectin serine peptidase 1	0.134
Tpra1	transmembrane protein, adipocyte asscociated 1	0.134
Pou3f2	POU domain, class 3, transcription factor 2	0.134	Mouse
Star	steroidogenic acute regulatory protein	0.134