IMP: Integrative Multi-species Prediction

Mus musculus

82 genes annotated in mouse

columnar cuboidal epithelial cell differentiation

GO:0002065

The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "columnar cuboidal epithelial cell differentiation"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "columnar cuboidal epithelial cell differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
Shh	sonic hedgehog	1.000
Pten	phosphatase and tensin homolog	1.000
Pax3	paired box gene 3	1.000
Fgf8	fibroblast growth factor 8	1.000
Otx2	orthodenticle homolog 2 (Drosophila)	0.999
Fgfr2	fibroblast growth factor receptor 2	0.999
Tcfap2a	transcription factor AP-2, alpha	0.999	Zebrafish
Foxc1	forkhead box C1	0.998	Mouse
Sox9	SRY-box containing gene 9	0.998	Mouse
Gli3	GLI-Kruppel family member GLI3	0.998
Foxc2	forkhead box C2	0.997	Mouse
Foxa2	forkhead box A2	0.997	Mouse Fly
Pax8	paired box gene 8	0.997
Meox2	mesenchyme homeobox 2	0.997
Mitf	microphthalmia-associated transcription factor	0.997
Isl1	ISL1 transcription factor, LIM/homeodomain	0.996	Zebrafish
Fgfr1	fibroblast growth factor receptor 1	0.995	Mouse Fly
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.994
Gli2	GLI-Kruppel family member GLI2	0.994	Mouse
Trp53	transformation related protein 53	0.994	Mouse
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.993	Mouse Fly
Hand2	heart and neural crest derivatives expressed transcript 2	0.991	Mouse
Hes1	hairy and enhancer of split 1 (Drosophila)	0.989
Pitx2	paired-like homeodomain transcription factor 2	0.988
Tbx1	T-box 1	0.981
Psen1	presenilin 1	0.979	Zebrafish
Vegfa	vascular endothelial growth factor A	0.977	Fly
Kit	kit oncogene	0.972
Ctnnb1	catenin (cadherin associated protein), beta 1	0.970
Ikzf1	IKAROS family zinc finger 1	0.966
Rarg	retinoic acid receptor, gamma	0.964
Bmp7	bone morphogenetic protein 7	0.962	Mouse Fly
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.961
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.954	Fly
a	nonagouti	0.954
Lyst	lysosomal trafficking regulator	0.954
Nodal	nodal	0.950
Pax6	paired box gene 6	0.948
Bmp4	bone morphogenetic protein 4	0.948	Human Mouse Fly
Lhx1	LIM homeobox protein 1	0.947
Pou5f1	POU domain, class 5, transcription factor 1	0.947
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.946
Notch2	Notch gene homolog 2 (Drosophila)	0.944	Mouse Fly
Pax2	paired box gene 2	0.931
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.927
Tal1	T-cell acute lymphocytic leukemia 1	0.927	Mouse
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.923	Mouse
Rara	retinoic acid receptor, alpha	0.916
Nkx2-1	NK2 homeobox 1	0.914	Mouse
Lhx3	LIM homeobox protein 3	0.900
Prrx1	paired related homeobox 1	0.894
Sox2	SRY-box containing gene 2	0.893	Mouse
Ahr	aryl-hydrocarbon receptor	0.889
Eya1	eyes absent 1 homolog (Drosophila)	0.886	Fly
Hoxd3	homeobox D3	0.875
Zic3	zinc finger protein of the cerebellum 3	0.874
Hoxa3	homeobox A3	0.866
Hoxa5	homeobox A5	0.863
Hoxb3	homeobox B3	0.858
Kitl	kit ligand	0.854
Hoxb4	homeobox B4	0.842	Mouse
Insm1	insulinoma-associated 1	0.840
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.839
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.834
Wnt3a	wingless-related MMTV integration site 3A	0.823	Mouse
Grb10	growth factor receptor bound protein 10	0.819
Fgf10	fibroblast growth factor 10	0.818	Mouse
Pthlh	parathyroid hormone-like peptide	0.814
Ret	ret proto-oncogene	0.814
Emx1	empty spiracles homolog 1 (Drosophila)	0.812
Rarb	retinoic acid receptor, beta	0.809
Emx2	empty spiracles homolog 2 (Drosophila)	0.808
Fyn	Fyn proto-oncogene	0.800	Mouse Fly
Gata4	GATA binding protein 4	0.799	Human Mouse
Hoxa11	homeobox A11	0.791
Pou3f3	POU domain, class 3, transcription factor 3	0.789
Nog	noggin	0.786
Hand1	heart and neural crest derivatives expressed transcript 1	0.777	Mouse
Chrd	chordin	0.777
En1	engrailed 1	0.772
Chd7	chromodomain helicase DNA binding protein 7	0.764	Fly
Neurod1	neurogenic differentiation 1	0.760
Ptf1a	pancreas specific transcription factor, 1a	0.759	Mouse
Tyrp1	tyrosinase-related protein 1	0.751
Sox10	SRY-box containing gene 10	0.748
Gbx2	gastrulation brain homeobox 2	0.745
Csf1	colony stimulating factor 1 (macrophage)	0.740
Vangl2	vang-like 2 (van gogh, Drosophila)	0.736	Fly
Fgf15	fibroblast growth factor 15	0.721
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.717
Hoxa13	homeobox A13	0.706
Msx1	homeobox, msh-like 1	0.706
Ednrb	endothelin receptor type B	0.683
Epor	erythropoietin receptor	0.682
Hoxa1	homeobox A1	0.678
Nos3	nitric oxide synthase 3, endothelial cell	0.670
Msx2	homeobox, msh-like 2	0.662
Notch1	Notch gene homolog 1 (Drosophila)	0.658
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.658
Tcf15	transcription factor 15	0.656	Mouse
Pbx1	pre B-cell leukemia transcription factor 1	0.654
Igf2	insulin-like growth factor 2	0.651
Gdnf	glial cell line derived neurotrophic factor	0.649
Sox7	SRY-box containing gene 7	0.648	Mouse
Ptch1	patched homolog 1	0.643
Neurog1	neurogenin 1	0.640	Mouse
Wnt1	wingless-related MMTV integration site 1	0.633	Mouse Fly
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.629	Mouse
Foxh1	forkhead box H1	0.624
Smad4	MAD homolog 4 (Drosophila)	0.623	Fly
Gata6	GATA binding protein 6	0.616
Hoxb6	homeobox B6	0.615	Mouse
Cdx1	caudal type homeobox 1	0.591
Ptch2	patched homolog 2	0.584
Sox4	SRY-box containing gene 4	0.583
She	src homology 2 domain-containing transforming protein E	0.581
Nf1	neurofibromatosis 1	0.581
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.581
Mesp1	mesoderm posterior 1	0.569
Tbx3	T-box 3	0.565
Lmx1a	LIM homeobox transcription factor 1 alpha	0.561
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.560
Rb1	retinoblastoma 1	0.557
Mlph	melanophilin	0.540
Uncx	UNC homeobox	0.535
Tcfap2c	transcription factor AP-2, gamma	0.531
Bdkrb2	bradykinin receptor, beta 2	0.530
Dll1	delta-like 1 (Drosophila)	0.529	Fly
Apc	adenomatosis polyposis coli	0.528
Tcfap2b	transcription factor AP-2 beta	0.526
Sox1	SRY-box containing gene 1	0.523
Sall3	sal-like 3 (Drosophila)	0.522
Tgfbr2	transforming growth factor, beta receptor II	0.517
Zic4	zinc finger protein of the cerebellum 4	0.515
Neurog2	neurogenin 2	0.505	Mouse
Acvr1	activin A receptor, type 1	0.504	Fly
Gsc	goosecoid homeobox	0.500
Kdr	kinase insert domain protein receptor	0.499	Mouse Fly
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.496	Fly
Ap3b1	adaptor-related protein complex 3, beta 1 subunit	0.494
Jag1	jagged 1	0.492
Pdx1	pancreatic and duodenal homeobox 1	0.492	Human
Hoxc5	homeobox C5	0.492	Mouse
Hoxb5	homeobox B5	0.476	Mouse
Msi1	Musashi homolog 1(Drosophila)	0.472
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.472
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.470
Hoxb9	homeobox B9	0.462
Bcl2	B-cell leukemia/lymphoma 2	0.460
Gata5	GATA binding protein 5	0.459	Mouse
Nkx6-1	NK6 homeobox 1	0.458	Zebrafish Mouse Rat
Ednra	endothelin receptor type A	0.453	Mouse
Lhx5	LIM homeobox protein 5	0.450
Hoxd13	homeobox D13	0.436
Foxa1	forkhead box A1	0.427
Clock	circadian locomotor output cycles kaput	0.425
Cbl	Casitas B-lineage lymphoma	0.421	Fly
Kcnk3	potassium channel, subfamily K, member 3	0.415
Dlx5	distal-less homeobox 5	0.397
Nrp1	neuropilin 1	0.393
Foxf1a	forkhead box F1a	0.393
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.375
Foxd3	forkhead box D3	0.374	Zebrafish Mouse
Epas1	endothelial PAS domain protein 1	0.373	Mouse
Sox3	SRY-box containing gene 3	0.369	Mouse
Hif1a	hypoxia inducible factor 1, alpha subunit	0.364
Smo	smoothened homolog (Drosophila)	0.352
Tgfb2	transforming growth factor, beta 2	0.351
Atoh1	atonal homolog 1 (Drosophila)	0.348	Mouse
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.347
Foxp1	forkhead box P1	0.347
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.345
Fgfr3	fibroblast growth factor receptor 3	0.345	Mouse Fly
Sim1	single-minded homolog 1 (Drosophila)	0.342	Mouse
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.339
Trp63	transformation related protein 63	0.339
Onecut1	one cut domain, family member 1	0.337
Neurog3	neurogenin 3	0.331	Mouse
Ar	androgen receptor	0.330
Bdnf	brain derived neurotrophic factor	0.330
Pou2f2	POU domain, class 2, transcription factor 2	0.324
Barx1	BarH-like homeobox 1	0.323
Barx2	BarH-like homeobox 2	0.320
Tgfb1	transforming growth factor, beta 1	0.319
Foxg1	forkhead box G1	0.318	Mouse
Tbx2	T-box 2	0.317
Fgf18	fibroblast growth factor 18	0.317	Mouse
Myod1	myogenic differentiation 1	0.316
Alx4	aristaless-like homeobox 4	0.315
Ece1	endothelin converting enzyme 1	0.314
Hes3	hairy and enhancer of split 3 (Drosophila)	0.313	Mouse
Gli1	GLI-Kruppel family member GLI1	0.311	Mouse
Wnt4	wingless-related MMTV integration site 4	0.306
Mef2c	myocyte enhancer factor 2C	0.304
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.304
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.303
T	brachyury	0.296
Otx1	orthodenticle homolog 1 (Drosophila)	0.294
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.293
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.291
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.290
Hmx3	H6 homeobox 3	0.288
Pou3f1	POU domain, class 3, transcription factor 1	0.286
Hoxb7	homeobox B7	0.286	Mouse
Foxn1	forkhead box N1	0.285
Duox2	dual oxidase 2	0.282
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.279	Mouse
Hoxd8	homeobox D8	0.279	Mouse
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.278
Slc25a48	solute carrier family 25, member 48	0.277
Sall4	sal-like 4 (Drosophila)	0.277
Cdk4	cyclin-dependent kinase 4	0.277
Fzd4	frizzled homolog 4 (Drosophila)	0.275
Hnf1b	HNF1 homeobox B	0.274	Zebrafish
En2	engrailed 2	0.272
Per2	period homolog 2 (Drosophila)	0.272
Glra1	glycine receptor, alpha 1 subunit	0.271
Hhex	hematopoietically expressed homeobox	0.271
Pitx1	paired-like homeodomain transcription factor 1	0.270
Foxd2	forkhead box D2	0.268	Mouse
Cdh5	cadherin 5	0.263
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.262
Pou4f2	POU domain, class 4, transcription factor 2	0.260
Hoxd11	homeobox D11	0.260
Fabp9	fatty acid binding protein 9, testis	0.259
Pax7	paired box gene 7	0.256
Wnt2b	wingless related MMTV integration site 2b	0.255	Mouse
Zic1	zinc finger protein of the cerebellum 1	0.253
Fgf4	fibroblast growth factor 4	0.253	Mouse
Smad3	MAD homolog 3 (Drosophila)	0.252
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.245	Fly
Prox1	prospero-related homeobox 1	0.244
Pitx3	paired-like homeodomain transcription factor 3	0.244
Tcf4	transcription factor 4	0.243	Fly
Hoxa2	homeobox A2	0.241
Mmp24	matrix metallopeptidase 24	0.241
Gdf1	growth differentiation factor 1	0.239	Mouse Fly
Pmel	premelanosome protein	0.239
Fgf17	fibroblast growth factor 17	0.238	Mouse
Hoxd9	homeobox D9	0.235
Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.227
Cbfa2t3	core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)	0.226
Flt4	FMS-like tyrosine kinase 4	0.226	Mouse Fly
Nkx3-2	NK3 homeobox 2	0.225
Mks1	Meckel syndrome, type 1	0.224
Sox17	SRY-box containing gene 17	0.223	Mouse
Pou3f4	POU domain, class 3, transcription factor 4	0.223
Mef2a	myocyte enhancer factor 2A	0.220	Mouse
Pou3f2	POU domain, class 3, transcription factor 2	0.219
Amhr2	anti-Mullerian hormone type 2 receptor	0.219
Mab21l2	mab-21-like 2 (C. elegans)	0.218
Rxra	retinoid X receptor alpha	0.216
Nkx2-6	NK2 transcription factor related, locus 6 (Drosophila)	0.214	Mouse
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.214
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.213
Ets1	E26 avian leukemia oncogene 1, 5' domain	0.213
Igfbpl1	insulin-like growth factor binding protein-like 1	0.213
Tal2	T-cell acute lymphocytic leukemia 2	0.212	Mouse
Cldn5	claudin 5	0.211
Jag2	jagged 2	0.211
Lama3	laminin, alpha 3	0.210
Tsc2	tuberous sclerosis 2	0.210
Zfp185	zinc finger protein 185	0.209
Vax1	ventral anterior homeobox containing gene 1	0.207
Ascl2	achaete-scute complex homolog 2 (Drosophila)	0.206	Mouse
Mecom	MDS1 and EVI1 complex locus	0.206
Snai1	snail homolog 1 (Drosophila)	0.202
Tyr	tyrosinase	0.200	Mouse
Myog	myogenin	0.199
Dab1	disabled homolog 1 (Drosophila)	0.193
Sall1	sal-like 1 (Drosophila)	0.191
Nfib	nuclear factor I/B	0.191
Ldb2	LIM domain binding 2	0.191
Adra2b	adrenergic receptor, alpha 2b	0.188
Zfpm2	zinc finger protein, multitype 2	0.187
Hes5	hairy and enhancer of split 5 (Drosophila)	0.185	Mouse
Notch4	Notch gene homolog 4 (Drosophila)	0.185	Mouse Fly
Cry1	cryptochrome 1 (photolyase-like)	0.181
Hlx	H2.0-like homeobox	0.181
Thra	thyroid hormone receptor alpha	0.180	Mouse
Ddx60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.179
Fgf3	fibroblast growth factor 3	0.179	Mouse
Rem1	rad and gem related GTP binding protein 1	0.178
Runx2	runt related transcription factor 2	0.177
Aicda	activation-induced cytidine deaminase	0.173
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.173	Mouse
Usp8	ubiquitin specific peptidase 8	0.172
Inpp5d	inositol polyphosphate-5-phosphatase D	0.171
Padi3	peptidyl arginine deiminase, type III	0.171
Grpr	gastrin releasing peptide receptor	0.171	Mouse
Rax	retina and anterior neural fold homeobox	0.169
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.167
Ebf3	early B-cell factor 3	0.167
Wnt6	wingless-related MMTV integration site 6	0.165	Mouse
Efnb1	ephrin B1	0.165
Myf5	myogenic factor 5	0.164
Cer1	cerberus 1 homolog (Xenopus laevis)	0.164
Hps1	Hermansky-Pudlak syndrome 1 homolog (human)	0.162
BC021891	cDNA sequence BC021891	0.160	Fly
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.159
Edn3	endothelin 3	0.159
Sfpi1	SFFV proviral integration 1	0.158
Rfx2	regulatory factor X, 2 (influences HLA class II expression)	0.157
Hif3a	hypoxia inducible factor 3, alpha subunit	0.156	Mouse
Twist2	twist homolog 2 (Drosophila)	0.156	Mouse
Dll4	delta-like 4 (Drosophila)	0.154	Fly
Cxcl12	chemokine (C-X-C motif) ligand 12	0.153
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.151
Hoxc4	homeobox C4	0.150	Mouse
Lmx1b	LIM homeobox transcription factor 1 beta	0.150
Cldn8	claudin 8	0.150
Ehf	ets homologous factor	0.150	Mouse
Tcf21	transcription factor 21	0.149
Nkx2-9	NK2 transcription factor related, locus 9 (Drosophila)	0.149	Mouse
Cd19	CD19 antigen	0.148
Zfp503	zinc finger protein 503	0.147
Hnf1a	HNF1 homeobox A	0.146
Mdm2	transformed mouse 3T3 cell double minute 2	0.146
Hoxa4	homeobox A4	0.146	Mouse
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.146
Cdx2	caudal type homeobox 2	0.145
Efna2	ephrin A2	0.145
Hoxa9	homeobox A9	0.143
Hic1	hypermethylated in cancer 1	0.143
Hmx1	H6 homeobox 1	0.143
Sox13	SRY-box containing gene 13	0.143
Kcna1	potassium voltage-gated channel, shaker-related subfamily, member 1	0.142
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.141
Was	Wiskott-Aldrich syndrome homolog (human)	0.141
Bcl6b	B-cell CLL/lymphoma 6, member B	0.138
Foxb1	forkhead box B1	0.138
Srcin1	SRC kinase signaling inhibitor 1	0.138
Rab27a	RAB27A, member RAS oncogene family	0.137
Cdc42ep1	CDC42 effector protein (Rho GTPase binding) 1	0.136
Tlx3	T-cell leukemia, homeobox 3	0.135
Hoxc6	homeobox C6	0.135	Mouse
Gpr50	G-protein-coupled receptor 50	0.135
Eya4	eyes absent 4 homolog (Drosophila)	0.134	Fly
Wnt8b	wingless related MMTV integration site 8b	0.134	Mouse
Fam164c	family with sequence similarity 164, member C	0.133
Fos	FBJ osteosarcoma oncogene	0.132	Fly
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.131
Twist1	twist homolog 1 (Drosophila)	0.131	Mouse
Ctf1	cardiotrophin 1	0.131
Hoxd1	homeobox D1	0.131
Pgr	progesterone receptor	0.130
Lepr	leptin receptor	0.129
Irf8	interferon regulatory factor 8	0.128
Wnt9a	wingless-type MMTV integration site 9A	0.128	Mouse
Efnb2	ephrin B2	0.128
Wnt3	wingless-related MMTV integration site 3	0.128	Mouse
Socs1	suppressor of cytokine signaling 1	0.128
Id1	inhibitor of DNA binding 1	0.128	Fly
Meox1	mesenchyme homeobox 1	0.127
Hoxa7	homeobox A7	0.127	Mouse
Sox21	SRY-box containing gene 21	0.126
Clcnka	chloride channel Ka	0.126
Insr	insulin receptor	0.126	Mouse
Foxd1	forkhead box D1	0.126	Mouse
Esr2	estrogen receptor 2 (beta)	0.124
Etv2	ets variant gene 2	0.123
Lama5	laminin, alpha 5	0.123
Prf1	perforin 1 (pore forming protein)	0.123
Dsg2	desmoglein 2	0.122
Gnrh1	gonadotropin releasing hormone 1	0.122
Wnt10b	wingless related MMTV integration site 10b	0.121	Mouse
Tbx15	T-box 15	0.121
Krt27	keratin 27	0.120
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.120
Odz2	odd Oz/ten-m homolog 2 (Drosophila)	0.119
Zic2	zinc finger protein of the cerebellum 2	0.118
5730559C18Rik	RIKEN cDNA 5730559C18 gene	0.118
Tacr2	tachykinin receptor 2	0.118
Ephb2	Eph receptor B2	0.116
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.115
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.115
Rab25	RAB25, member RAS oncogene family	0.115	Fly
Phox2b	paired-like homeobox 2b	0.114
Adra2a	adrenergic receptor, alpha 2a	0.114
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.114
Smad6	MAD homolog 6 (Drosophila)	0.114
Ntn1	netrin 1	0.113
Nhlh1	nescient helix loop helix 1	0.111	Mouse
Rasip1	Ras interacting protein 1	0.111
Tpo	thyroid peroxidase	0.111
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.110	Mouse Fly
Odz4	odd Oz/ten-m homolog 4 (Drosophila)	0.109
Hoxb13	homeobox B13	0.109
Cry2	cryptochrome 2 (photolyase-like)	0.108
Plxnd1	plexin D1	0.108
Ccnd1	cyclin D1	0.108
Ptpre	protein tyrosine phosphatase, receptor type, E	0.107
Utf1	undifferentiated embryonic cell transcription factor 1	0.107
Wnt7a	wingless-related MMTV integration site 7A	0.107	Mouse
Foxi3	forkhead box I3	0.106
Cldn4	claudin 4	0.106
Plcg2	phospholipase C, gamma 2	0.106	Fly
Foxp2	forkhead box P2	0.106	Mouse
Efna3	ephrin A3	0.106
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.105
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.105
Ntf3	neurotrophin 3	0.105
Zeb1	zinc finger E-box binding homeobox 1	0.104	Mouse
Tead3	TEA domain family member 3	0.103
Col22a1	collagen, type XXII, alpha 1	0.102
Fzd8	frizzled homolog 8 (Drosophila)	0.101
Casp14	caspase 14	0.101
Cd2ap	CD2-associated protein	0.101	Fly
Met	met proto-oncogene	0.099
Hoxd4	homeobox D4	0.099	Mouse
Hoxa10	homeobox A10	0.099
Ap3d1	adaptor-related protein complex 3, delta 1 subunit	0.099
Gjb4	gap junction protein, beta 4	0.098
Msh2	mutS homolog 2 (E. coli)	0.098
Hist1h1t	histone cluster 1, H1t	0.098
Cxadr	coxsackie virus and adenovirus receptor	0.098
Mnx1	motor neuron and pancreas homeobox 1	0.098	Zebrafish Fly
Klf7	Kruppel-like factor 7 (ubiquitous)	0.097	Mouse
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.096
Fgfbp1	fibroblast growth factor binding protein 1	0.095
Lbx1	ladybird homeobox homolog 1 (Drosophila)	0.095
Cdh1	cadherin 1	0.095
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.094
Btbd17	BTB (POZ) domain containing 17	0.094
Sema5b	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B	0.094
Otp	orthopedia homolog (Drosophila)	0.093
Hoxc9	homeobox C9	0.093
Sfrp5	secreted frizzled-related sequence protein 5	0.093
Hoxb2	homeobox B2	0.093
Fzd10	frizzled homolog 10 (Drosophila)	0.092
Epha1	Eph receptor A1	0.092
Igf2bp1	insulin-like growth factor 2 mRNA binding protein 1	0.092
Skor1	SKI family transcriptional corepressor 1	0.092
Nat3	N-acetyltransferase 3	0.092
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.092
Krt34	keratin 34	0.092
Pik3c2g	phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide	0.091
Efna4	ephrin A4	0.091
Foxo4	forkhead box O4	0.090
Spnb2	spectrin beta 2	0.090
Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.090
Thbs1	thrombospondin 1	0.090
Sox18	SRY-box containing gene 18	0.090	Mouse
Casr	calcium-sensing receptor	0.089
Jak2	Janus kinase 2	0.089	Fly
Evx1	even skipped homeotic gene 1 homolog	0.089
Phlda2	pleckstrin homology-like domain, family A, member 2	0.089
Spry4	sprouty homolog 4 (Drosophila)	0.088
Tmprss2	transmembrane protease, serine 2	0.088
Foxe1	forkhead box E1	0.088	Mouse
Slc34a2	solute carrier family 34 (sodium phosphate), member 2	0.087
Stra8	stimulated by retinoic acid gene 8	0.087
Dmrt1	doublesex and mab-3 related transcription factor 1	0.087
Atm	ataxia telangiectasia mutated homolog (human)	0.086
Rhob	ras homolog gene family, member B	0.086
Zbtb46	zinc finger and BTB domain containing 46	0.086
Cdh16	cadherin 16	0.086
Gcm2	glial cells missing homolog 2 (Drosophila)	0.086
Arx	aristaless related homeobox	0.086	Zebrafish
Krt84	keratin 84	0.086
Arvcf	armadillo repeat gene deleted in velo-cardio-facial syndrome	0.086
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.085
Hrh1	histamine receptor H1	0.085
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.085
Usp43	ubiquitin specific peptidase 43	0.085
Ptprb	protein tyrosine phosphatase, receptor type, B	0.085
Hps5	Hermansky-Pudlak syndrome 5 homolog (human)	0.084
Cited4	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4	0.084	Mouse
Ren1	renin 1 structural	0.083
Cxcr4	chemokine (C-X-C motif) receptor 4	0.083
Myt1	myelin transcription factor 1	0.082
Onecut3	one cut domain, family member 3	0.082
Tcl1	T-cell lymphoma breakpoint 1	0.082
Lgr5	leucine rich repeat containing G protein coupled receptor 5	0.082
Tlx2	T-cell leukemia, homeobox 2	0.082
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.082	Fly
Oprd1	opioid receptor, delta 1	0.082
Grid1	glutamate receptor, ionotropic, delta 1	0.081
Spdef	SAM pointed domain containing ets transcription factor	0.081
Dhh	desert hedgehog	0.081
Wnt9b	wingless-type MMTV integration site 9B	0.081	Mouse
Ep300	E1A binding protein p300	0.081
Dmrt3	doublesex and mab-3 related transcription factor 3	0.080
Efs	embryonal Fyn-associated substrate	0.080
Foxe3	forkhead box E3	0.080	Mouse
Neurod4	neurogenic differentiation 4	0.080	Mouse
Lmo1	LIM domain only 1	0.080
Foxf2	forkhead box F2	0.080
Esrrb	estrogen related receptor, beta	0.079
Odf3	outer dense fiber of sperm tails 3	0.079
Ptgdr	prostaglandin D receptor	0.079
Pax5	paired box gene 5	0.079
Cno	cappuccino	0.079
Ihh	Indian hedgehog	0.079
Evx2	even skipped homeotic gene 2 homolog	0.079
Ghr	growth hormone receptor	0.079
Ccnd2	cyclin D2	0.079
Prkce	protein kinase C, epsilon	0.078
Zscan2	zinc finger and SCAN domain containing 2	0.078
Huwe1	HECT, UBA and WWE domain containing 1	0.078
Prph	peripherin	0.078
Amotl2	angiomotin-like 2	0.078
Hdac7	histone deacetylase 7	0.078
Cldn2	claudin 2	0.078
Npas2	neuronal PAS domain protein 2	0.077	Mouse
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.077	Fly
Lfng	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	0.077
Unc93b1	unc-93 homolog B1 (C. elegans)	0.077
Tek	endothelial-specific receptor tyrosine kinase	0.077
Ddr2	discoidin domain receptor family, member 2	0.076
Bax	BCL2-associated X protein	0.076	Mouse
Otog	otogelin	0.075
Foxo1	forkhead box O1	0.074
Dlx3	distal-less homeobox 3	0.073
Hmga1	high mobility group AT-hook 1	0.073
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.073	Mouse Fly
Acan	aggrecan	0.073
Hoxc8	homeobox C8	0.072	Mouse
Gna13	guanine nucleotide binding protein, alpha 13	0.072	Mouse
Fst	follistatin	0.072
Zbtb7c	zinc finger and BTB domain containing 7C	0.072
Gipc3	GIPC PDZ domain containing family, member 3	0.072
Papln	papilin, proteoglycan-like sulfated glycoprotein	0.072
Hmga2	high mobility group AT-hook 2	0.072
Hdac5	histone deacetylase 5	0.072
Gp9	glycoprotein 9 (platelet)	0.072
Mdm4	transformed mouse 3T3 cell double minute 4	0.071
Emid2	EMI domain containing 2	0.070
Smad7	MAD homolog 7 (Drosophila)	0.070
Rbpjl	recombination signal binding protein for immunoglobulin kappa J region-like	0.070
Smad2	MAD homolog 2 (Drosophila)	0.069
Fgfrl1	fibroblast growth factor receptor-like 1	0.069
Pkdcc	protein kinase domain containing, cytoplasmic	0.069
Id2	inhibitor of DNA binding 2	0.069	Fly
Esrp2	epithelial splicing regulatory protein 2	0.069
Fli1	Friend leukemia integration 1	0.068
Gna11	guanine nucleotide binding protein, alpha 11	0.068
Ifnb1	interferon beta 1, fibroblast	0.068
Sim2	single-minded homolog 2 (Drosophila)	0.068	Mouse
Rfwd2	ring finger and WD repeat domain 2	0.068
Cldn6	claudin 6	0.068
Card11	caspase recruitment domain family, member 11	0.068
Fzd6	frizzled homolog 6 (Drosophila)	0.068	Fly
Npr1	natriuretic peptide receptor 1	0.068
Eng	endoglin	0.068
Xpa	xeroderma pigmentosum, complementation group A	0.068
Gjb5	gap junction protein, beta 5	0.068
Wsb1	WD repeat and SOCS box-containing 1	0.067
Hs3st3a1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	0.067
Kiss1	KiSS-1 metastasis-suppressor	0.067
Adam17	a disintegrin and metallopeptidase domain 17	0.066
Dlx1	distal-less homeobox 1	0.066
Prrx2	paired related homeobox 2	0.066
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.066
Atoh8	atonal homolog 8 (Drosophila)	0.066
Omp	olfactory marker protein	0.066
Atp4a	ATPase, H+/K+ exchanging, gastric, alpha polypeptide	0.066
Tcirg1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3	0.066
Matn3	matrilin 3	0.066
Hcrt	hypocretin	0.066
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.065
Fgd5	FYVE, RhoGEF and PH domain containing 5	0.065
Bak1	BCL2-antagonist/killer 1	0.065	Mouse
Guca2a	guanylate cyclase activator 2a (guanylin)	0.065
Epha4	Eph receptor A4	0.065
Marveld3	MARVEL (membrane-associating) domain containing 3	0.064
B4galnt2	beta-1,4-N-acetyl-galactosaminyl transferase 2	0.064
Ager	advanced glycosylation end product-specific receptor	0.064
Irx1	Iroquois related homeobox 1 (Drosophila)	0.064
Pax9	paired box gene 9	0.064
Tas1r1	taste receptor, type 1, member 1	0.063
Zfp771	zinc finger protein 771	0.063
Nppc	natriuretic peptide type C	0.063
Tert	telomerase reverse transcriptase	0.063
Tulp2	tubby-like protein 2	0.063
Nr0b1	nuclear receptor subfamily 0, group B, member 1	0.063
Hoxb8	homeobox B8	0.063	Mouse
Fam151a	family with sequence simliarity 151, member A	0.062
Aff1	AF4/FMR2 family, member 1	0.062
Pla2g10	phospholipase A2, group X	0.062
Blnk	B-cell linker	0.062
Pcdh12	protocadherin 12	0.061
AI428936	expressed sequence AI428936	0.061
Crxos1	Crx opposite strand transcript 1	0.061
Timp3	tissue inhibitor of metalloproteinase 3	0.060
Gpc3	glypican 3	0.060
Alox12	arachidonate 12-lipoxygenase	0.060
Flt1	FMS-like tyrosine kinase 1	0.060	Mouse Fly
Rint1	RAD50 interactor 1	0.060
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.060	Fly
Tg	thyroglobulin	0.059
Wt1	Wilms tumor 1 homolog	0.059
Fhl3	four and a half LIM domains 3	0.059
Bik	BCL2-interacting killer	0.059
Ptk7	PTK7 protein tyrosine kinase 7	0.059
Cpxm2	carboxypeptidase X 2 (M14 family)	0.059
Fut7	fucosyltransferase 7	0.059
Egfr	epidermal growth factor receptor	0.059	Fly
Rgnef	Rho-guanine nucleotide exchange factor	0.059
Hmgb4	high-mobility group box 4	0.059
Gsx1	GS homeobox 1	0.058
Hdac4	histone deacetylase 4	0.058
Ncoa1	nuclear receptor coactivator 1	0.058
Fgf14	fibroblast growth factor 14	0.058	Mouse
Cdh3	cadherin 3	0.058	Mouse
Esam	endothelial cell-specific adhesion molecule	0.058
Aplnr	apelin receptor	0.058
Npas1	neuronal PAS domain protein 1	0.058	Mouse
Cfc1	cripto, FRL-1, cryptic family 1	0.058
Gjc2	gap junction protein, gamma 2	0.058
Emcn	endomucin	0.058
Cdh13	cadherin 13	0.058	Mouse
Acvr2b	activin receptor IIB	0.058
Mpl	myeloproliferative leukemia virus oncogene	0.058
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.058
Krtap6-3	keratin associated protein 6-3	0.057
Gdf3	growth differentiation factor 3	0.057	Mouse Fly
Fgf23	fibroblast growth factor 23	0.057
Adamts9	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 9	0.057
Col13a1	collagen, type XIII, alpha 1	0.057
Pofut1	protein O-fucosyltransferase 1	0.057
Tecta	tectorin alpha	0.057
Rhox6	reproductive homeobox 6	0.056
Rhpn1	rhophilin, Rho GTPase binding protein 1	0.056
Sfrp2	secreted frizzled-related protein 2	0.056
Olig2	oligodendrocyte transcription factor 2	0.056
Crlf1	cytokine receptor-like factor 1	0.056
Mgat3	mannoside acetylglucosaminyltransferase 3	0.056
Pax1	paired box gene 1	0.056
Hck	hemopoietic cell kinase	0.056	Mouse Fly
Cd247	CD247 antigen	0.056
Ebf2	early B-cell factor 2	0.056
Ptk2	PTK2 protein tyrosine kinase 2	0.056
Grin2d	glutamate receptor, ionotropic, NMDA2D (epsilon 4)	0.055
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.055	Fly
Ppard	peroxisome proliferator activator receptor delta	0.055
Nkx2-4	NK2 transcription factor related, locus 4 (Drosophila)	0.055	Mouse
Krt16	keratin 16	0.055
Tdgf1	teratocarcinoma-derived growth factor 1	0.055
Chrna7	cholinergic receptor, nicotinic, alpha polypeptide 7	0.055
Egfl7	EGF-like domain 7	0.055
Zfp518b	zinc finger protein 518B	0.055
Vipr2	vasoactive intestinal peptide receptor 2	0.054
Ly6g6c	lymphocyte antigen 6 complex, locus G6C	0.054
Bmp5	bone morphogenetic protein 5	0.054	Human Mouse Fly
Gja8	gap junction protein, alpha 8	0.054
Wnt11	wingless-related MMTV integration site 11	0.054	Mouse
Bmper	BMP-binding endothelial regulator	0.054
Wwc1	WW, C2 and coiled-coil domain containing 1	0.054
Cyp27b1	cytochrome P450, family 27, subfamily b, polypeptide 1	0.054
Fbn2	fibrillin 2	0.054
B9d1	B9 protein domain 1	0.053
Hbb-b1	hemoglobin, beta adult major chain	0.053
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.053
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.052
Plac1	placental specific protein 1	0.052
Pldn	pallidin	0.052
Usp25	ubiquitin specific peptidase 25	0.052
Bmp2	bone morphogenetic protein 2	0.052
Adamts20	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20	0.052
Ptprc	protein tyrosine phosphatase, receptor type, C	0.052
Mll5	myeloid/lymphoid or mixed-lineage leukemia 5	0.051
Sp5	trans-acting transcription factor 5	0.051
Prkdc	protein kinase, DNA activated, catalytic polypeptide	0.051
Hesx1	homeobox gene expressed in ES cells	0.051
Ccdc96	coiled-coil domain containing 96	0.051
Calcr	calcitonin receptor	0.051
Klk1b3	kallikrein 1-related peptidase b3	0.051
Fgf9	fibroblast growth factor 9	0.051	Mouse
Zfp444	zinc finger protein 444	0.051
Nkd1	naked cuticle 1 homolog (Drosophila)	0.051
Lhx9	LIM homeobox protein 9	0.051
Lyz2	lysozyme 2	0.050
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.050
Yap1	yes-associated protein 1	0.050	Fly
Myoz1	myozenin 1	0.050
Rbms1	RNA binding motif, single stranded interacting protein 1	0.050
Krt71	keratin 71	0.050
Gata1	GATA binding protein 1	0.050	Mouse
Adcy4	adenylate cyclase 4	0.050
Fut2	fucosyltransferase 2	0.050
Trpm1	transient receptor potential cation channel, subfamily M, member 1	0.049
Mycl1	v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)	0.049
Ptk6	PTK6 protein tyrosine kinase 6	0.049
Irs2	insulin receptor substrate 2	0.049
Crisp2	cysteine-rich secretory protein 2	0.049
Mmp15	matrix metallopeptidase 15	0.049
Pdgfb	platelet derived growth factor, B polypeptide	0.049	Fly
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.049
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.049
Cr2	complement receptor 2	0.048
Stra6	stimulated by retinoic acid gene 6	0.048
Hps6	Hermansky-Pudlak syndrome 6	0.048
Cckar	cholecystokinin A receptor	0.048
Wnt5a	wingless-related MMTV integration site 5A	0.048
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.048
Ncf1	neutrophil cytosolic factor 1	0.048
Nes	nestin	0.048
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.047
Sdc3	syndecan 3	0.047
Wnt7b	wingless-related MMTV integration site 7B	0.047	Mouse
Nfe2l3	nuclear factor, erythroid derived 2, like 3	0.047
Rlbp1	retinaldehyde binding protein 1	0.047
Ywhaq	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.047
Fndc7	fibronectin type III domain containing 7	0.046
Sh2b3	SH2B adaptor protein 3	0.046
Gja4	gap junction protein, alpha 4	0.046
Foxb2	forkhead box B2	0.046	Mouse
Gpsm3	G-protein signalling modulator 3 (AGS3-like, C. elegans)	0.046
Bnc1	basonuclin 1	0.046
Tiparp	TCDD-inducible poly(ADP-ribose) polymerase	0.046
Car12	carbonic anyhydrase 12	0.046
Tnp1	transition protein 1	0.046
Sox11	SRY-box containing gene 11	0.046
Krt35	keratin 35	0.046
Cpe	carboxypeptidase E	0.046
Syt9	synaptotagmin IX	0.046
Slc5a11	solute carrier family 5 (sodium/glucose cotransporter), member 11	0.045
Dll3	delta-like 3 (Drosophila)	0.045	Fly
Spry2	sprouty homolog 2 (Drosophila)	0.045
Smad1	MAD homolog 1 (Drosophila)	0.045	Fly
Ly6g6d	lymphocyte antigen 6 complex, locus G6D	0.045
Dach1	dachshund 1 (Drosophila)	0.045
Meis2	Meis homeobox 2	0.045
Rhbdl3	rhomboid, veinlet-like 3 (Drosophila)	0.045
Shox2	short stature homeobox 2	0.045
Sept1	septin 1	0.045
March7	membrane-associated ring finger (C3HC4) 7	0.045
Cdk5r2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.045
Mpzl2	myelin protein zero-like 2	0.045
Prm1	protamine 1	0.045
Fgf6	fibroblast growth factor 6	0.044	Mouse
Smarcd1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.044
Gfpt2	glutamine fructose-6-phosphate transaminase 2	0.044
Mipol1	mirror-image polydactyly gene 1 homolog (human)	0.044
Cyp2s1	cytochrome P450, family 2, subfamily s, polypeptide 1	0.044
Alox8	arachidonate 8-lipoxygenase	0.044
Map3k11	mitogen-activated protein kinase kinase kinase 11	0.044	Fly
Sykb	spleen tyrosine kinase	0.044	Fly
Scn7a	sodium channel, voltage-gated, type VII, alpha	0.044
Esr1	estrogen receptor 1 (alpha)	0.044
Ptrf	polymerase I and transcript release factor	0.044
Krt15	keratin 15	0.044
Elf3	E74-like factor 3	0.043	Mouse
Qk	quaking	0.043
Gja3	gap junction protein, alpha 3	0.043
Myc	myelocytomatosis oncogene	0.043
Mafb	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.043
St8sia1	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1	0.043
Foxm1	forkhead box M1	0.043