IMP: Integrative Multi-species Prediction

Mus musculus

100 genes annotated in mouse

response to insulin

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to insulin"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "response to insulin" (in gray)

Name	Description	Probability	Func Analog Organism
Lepr	leptin receptor	0.999
Clock	circadian locomotor output cycles kaput	0.997
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.968	Human
Pten	phosphatase and tensin homolog	0.961	Fly
Lep	leptin	0.958
Nos3	nitric oxide synthase 3, endothelial cell	0.946
Insr	insulin receptor	0.946
Ctnnb1	catenin (cadherin associated protein), beta 1	0.902
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.898
Pparg	peroxisome proliferator activated receptor gamma	0.894
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.885
Cbl	Casitas B-lineage lymphoma	0.882
Bglap	bone gamma carboxyglutamate protein	0.877	Mouse
Apoe	apolipoprotein E	0.837
Vegfa	vascular endothelial growth factor A	0.833
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.816
Csf1	colony stimulating factor 1 (macrophage)	0.812
Fyn	Fyn proto-oncogene	0.811
Prlr	prolactin receptor	0.757
Esr1	estrogen receptor 1 (alpha)	0.756
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.750
Nf1	neurofibromatosis 1	0.734
Apc	adenomatosis polyposis coli	0.725
Ghr	growth hormone receptor	0.717	Rat
Irs2	insulin receptor substrate 2	0.669
Mark4	MAP/microtubule affinity-regulating kinase 4	0.597	Mouse
Pnpla2	patatin-like phospholipase domain containing 2	0.595
Lhx3	LIM homeobox protein 3	0.590
Cav1	caveolin 1, caveolae protein	0.584
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.571
Jak2	Janus kinase 2	0.571
Agtr1a	angiotensin II receptor, type 1a	0.552
Vhl	von Hippel-Lindau tumor suppressor	0.550
Hif1a	hypoxia inducible factor 1, alpha subunit	0.544	Rat Fly
Egfr	epidermal growth factor receptor	0.540
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.511
Fshr	follicle stimulating hormone receptor	0.493
Ptk2	PTK2 protein tyrosine kinase 2	0.488
Kit	kit oncogene	0.484	Fly
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.467	Rat
Trp53	transformation related protein 53	0.444
Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	0.444
Tsc1	tuberous sclerosis 1	0.436	Human Fly
Stat3	signal transducer and activator of transcription 3	0.428
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.418	Mouse Rat Worm
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.416
Sim1	single-minded homolog 1 (Drosophila)	0.412
Amhr2	anti-Mullerian hormone type 2 receptor	0.408	Mouse
Tgfb1	transforming growth factor, beta 1	0.406
Ar	androgen receptor	0.403	Rat
Epas1	endothelial PAS domain protein 1	0.391	Fly
Ins2	insulin II	0.390
Smad3	MAD homolog 3 (Drosophila)	0.383
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.378
Efnb2	ephrin B2	0.374
Plcg1	phospholipase C, gamma 1	0.371	Fly
Pomc	pro-opiomelanocortin-alpha	0.344
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.344
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.341
Ahr	aryl-hydrocarbon receptor	0.338
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.335
Nos1	nitric oxide synthase 1, neuronal	0.329
Lipe	lipase, hormone sensitive	0.327
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.323
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.306
Mup19	major urinary protein 19	0.304	Mouse
C1qa	complement component 1, q subcomponent, alpha polypeptide	0.303	Mouse
Inpp5d	inositol polyphosphate-5-phosphatase D	0.289	Mouse
Alb	albumin	0.285
Otp	orthopedia homolog (Drosophila)	0.265
Epor	erythropoietin receptor	0.265
Notch2	Notch gene homolog 2 (Drosophila)	0.264
Kiss1r	KISS1 receptor	0.257
Serpina1c	serine (or cysteine) peptidase inhibitor, clade A, member 1C	0.254	Mouse
Inha	inhibin alpha	0.252
Nck2	non-catalytic region of tyrosine kinase adaptor protein 2	0.250	Fly
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.246
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.243
Kiss1	KiSS-1 metastasis-suppressor	0.241
Serpina3c	serine (or cysteine) peptidase inhibitor, clade A, member 3C	0.237	Mouse
Per3	period homolog 3 (Drosophila)	0.234
Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1	0.225
Igbp1	immunoglobulin (CD79A) binding protein 1	0.223
Ldlr	low density lipoprotein receptor	0.217
Dok1	docking protein 1	0.216
Acvrl1	activin A receptor, type II-like 1	0.212	Mouse
Zfp358	zinc finger protein 358	0.207
Braf	Braf transforming gene	0.206
Hr	hairless	0.205
Igf1r	insulin-like growth factor I receptor	0.205	Mouse Fly
Atf4	activating transcription factor 4	0.199
Ptprn	protein tyrosine phosphatase, receptor type, N	0.199	Rat
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.199	Mouse
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.192
Rictor	RPTOR independent companion of MTOR, complex 2	0.189
Wnk4	WNK lysine deficient protein kinase 4	0.188
Inhbc	inhibin beta-C	0.187	Mouse
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.186
Tek	endothelial-specific receptor tyrosine kinase	0.184
Efnb1	ephrin B1	0.183
Mapkap1	mitogen-activated protein kinase associated protein 1	0.182
LOC100048884	novel member of the major urinary protein (Mup) gene family	0.179	Mouse
Prkcc	protein kinase C, gamma	0.179	Mouse
Uox	urate oxidase	0.175
Htt	huntingtin	0.172
Dvl3	dishevelled 3, dsh homolog (Drosophila)	0.170
Grb10	growth factor receptor bound protein 10	0.169
Prkaca	protein kinase, cAMP dependent, catalytic, alpha	0.168
Gucy2e	guanylate cyclase 2e	0.167
Mc2r	melanocortin 2 receptor	0.163	Mouse
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.159
Npy1r	neuropeptide Y receptor Y1	0.157
Cidec	cell death-inducing DFFA-like effector c	0.153
Rb1	retinoblastoma 1	0.153
Nab2	Ngfi-A binding protein 2	0.153
Stat5a	signal transducer and activator of transcription 5A	0.153
Fst	follistatin	0.151
Tgfbr3	transforming growth factor, beta receptor III	0.151
Irs1	insulin receptor substrate 1	0.151
Mup9	major urinary protein 9	0.151	Mouse
Dab1	disabled homolog 1 (Drosophila)	0.149
Bcar1	breast cancer anti-estrogen resistance 1	0.145	Rat
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.145
Gab2	growth factor receptor bound protein 2-associated protein 2	0.144
Lrp1	low density lipoprotein receptor-related protein 1	0.144
Gata4	GATA binding protein 4	0.143
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.143
Ntf3	neurotrophin 3	0.139
Nf2	neurofibromatosis 2	0.139
S100a5	S100 calcium binding protein A5	0.138
Serpina6	serine (or cysteine) peptidase inhibitor, clade A, member 6	0.138	Mouse
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.136	Mouse
Ren1	renin 1 structural	0.135
Ptpn12	protein tyrosine phosphatase, non-receptor type 12	0.134
Ptgs2	prostaglandin-endoperoxide synthase 2	0.134
Ldb3	LIM domain binding 3	0.134
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.133
Nos2	nitric oxide synthase 2, inducible	0.132
Mup7	major urinary protein 7	0.131	Mouse
2310014H01Rik	RIKEN cDNA 2310014H01 gene	0.131
Per1	period homolog 1 (Drosophila)	0.130
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.129
Mup10	major urinary protein 10	0.129	Mouse
Mup14	major urinary protein 14	0.128	Mouse
Per2	period homolog 2 (Drosophila)	0.128
Sct	secretin	0.127
Add1	adducin 1 (alpha)	0.127
Actn2	actinin alpha 2	0.126
Akr1c6	aldo-keto reductase family 1, member C6	0.126
Foxo1	forkhead box O1	0.124
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.123
Kdr	kinase insert domain protein receptor	0.122	Fly
Vav2	vav 2 oncogene	0.121
Tyrobp	TYRO protein tyrosine kinase binding protein	0.121
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.121
Sox10	SRY-box containing gene 10	0.120
Cd36	CD36 antigen	0.120	Rat
Spnb3	spectrin beta 3	0.119
Mup1	major urinary protein 1	0.119
Ahsg	alpha-2-HS-glycoprotein	0.118
Gprc6a	G protein-coupled receptor, family C, group 6, member A	0.118
Gpr56	G protein-coupled receptor 56	0.118
Myc	myelocytomatosis oncogene	0.115
Cfd	complement factor D (adipsin)	0.114
Sik3	SIK family kinase 3	0.113	Mouse
Fbxl3	F-box and leucine-rich repeat protein 3	0.113
Grb2	growth factor receptor bound protein 2	0.113	Human
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.112
Prkce	protein kinase C, epsilon	0.111	Mouse
Car5a	carbonic anhydrase 5a, mitochondrial	0.110
Ptk2b	PTK2 protein tyrosine kinase 2 beta	0.109
Mark2	MAP/microtubule affinity-regulating kinase 2	0.109	Mouse
Mc5r	melanocortin 5 receptor	0.108	Mouse
Apoa1	apolipoprotein A-I	0.108
Kl	klotho	0.107
Fas	Fas (TNF receptor superfamily member 6)	0.107
Axin1	axin 1	0.105
Pim1	proviral integration site 1	0.105
Apoc4	apolipoprotein C-IV	0.105
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.105
Vgf	VGF nerve growth factor inducible	0.102
Foxo4	forkhead box O4	0.101	Human Mouse Worm Fly
Mup12	major urinary protein 12	0.101	Mouse
Ifnab	interferon alpha B	0.101
Mup8	major urinary protein 8	0.099	Mouse
C1qc	complement component 1, q subcomponent, C chain	0.099	Mouse
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.099
Akt3	thymoma viral proto-oncogene 3	0.099	Mouse Worm Fly
Ncs1	neuronal calcium sensor 1	0.099
Adipoq	adiponectin, C1Q and collagen domain containing	0.099
Nphs2	nephrosis 2 homolog, podocin (human)	0.098
Sirpa	signal-regulatory protein alpha	0.098
Mup4	major urinary protein 4	0.097	Mouse
Ep300	E1A binding protein p300	0.097
Cyfip1	cytoplasmic FMR1 interacting protein 1	0.096
Prf1	perforin 1 (pore forming protein)	0.096
Rxrg	retinoid X receptor gamma	0.096
Ece1	endothelin converting enzyme 1	0.096
Lyz2	lysozyme 2	0.095
Cd14	CD14 antigen	0.095
Ghrl	ghrelin	0.095
Rbl2	retinoblastoma-like 2	0.095
C1qb	complement component 1, q subcomponent, beta polypeptide	0.095	Mouse
Junb	Jun-B oncogene	0.095
Cish	cytokine inducible SH2-containing protein	0.095	Mouse
Ednra	endothelin receptor type A	0.095
Tnks1bp1	tankyrase 1 binding protein 1	0.094
Esr2	estrogen receptor 2 (beta)	0.094
Sorbs1	sorbin and SH3 domain containing 1	0.094
Slc27a1	solute carrier family 27 (fatty acid transporter), member 1	0.094
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.093
Plin1	perilipin 1	0.093
Epn1	epsin 1	0.092
Egln1	EGL nine homolog 1 (C. elegans)	0.092
Akt1	thymoma viral proto-oncogene 1	0.092
Col1a1	collagen, type I, alpha 1	0.091
Bglap2	bone gamma-carboxyglutamate protein 2	0.091
Tln1	talin 1	0.091
Spred1	sprouty protein with EVH-1 domain 1, related sequence	0.091
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.090	Fly
Mup2	major urinary protein 2	0.090	Mouse
Adam10	a disintegrin and metallopeptidase domain 10	0.089
Mup13	major urinary protein 13	0.089
Ulk1	Unc-51 like kinase 1 (C. elegans)	0.088
C3	complement component 3	0.088
Psg19	pregnancy specific glycoprotein 19	0.088
Il1a	interleukin 1 alpha	0.087	Mouse
Timp1	tissue inhibitor of metalloproteinase 1	0.087
Foxa2	forkhead box A2	0.087
Inhbb	inhibin beta-B	0.087
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.087
Neurog3	neurogenin 3	0.087
Vav3	vav 3 oncogene	0.086
Has1	hyaluronan synthase1	0.086
Baat	bile acid-Coenzyme A: amino acid N-acyltransferase	0.086
Chst8	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8	0.086
4921517D21Rik	RIKEN cDNA 4921517D21 gene	0.085
Inhba	inhibin beta-A	0.084	Mouse
Npc1	Niemann Pick type C1	0.083
Mitf	microphthalmia-associated transcription factor	0.082
Tbk1	TANK-binding kinase 1	0.082
Mup17	major urinary protein 17	0.082
Tdo2	tryptophan 2,3-dioxygenase	0.081
Gsk3a	glycogen synthase kinase 3 alpha	0.081
Drd2	dopamine receptor D2	0.081
Mup15	major urinary protein 15	0.081	Mouse
Smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.080
Gdnf	glial cell line derived neurotrophic factor	0.080
Trib3	tribbles homolog 3 (Drosophila)	0.080
Eng	endoglin	0.079
Hsd3b3	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3	0.079	Rat
Mup11	major urinary protein 11	0.079	Mouse
Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.079
Mgrn1	mahogunin, ring finger 1	0.079
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.078
Abcb9	ATP-binding cassette, sub-family B (MDR/TAP), member 9	0.078
Hrh1	histamine receptor H1	0.078
LOC100048885	major urinary protein LOC100048885	0.078	Mouse
Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.078
Ypel3	yippee-like 3 (Drosophila)	0.077
Cited1	Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1	0.077
Syt7	synaptotagmin VII	0.077
Gal	galanin	0.076	Rat
Atp9a	ATPase, class II, type 9A	0.076
Sorbs3	sorbin and SH3 domain containing 3	0.076	Mouse
Pcx	pyruvate carboxylase	0.076
Fli1	Friend leukemia integration 1	0.076
Rasa1	RAS p21 protein activator 1	0.076
Spry4	sprouty homolog 4 (Drosophila)	0.076
Aes	amino-terminal enhancer of split	0.075
Ctla2a	cytotoxic T lymphocyte-associated protein 2 alpha	0.075
Adra1a	adrenergic receptor, alpha 1a	0.075
Acvr2a	activin receptor IIA	0.074
Kcnk3	potassium channel, subfamily K, member 3	0.074
Hsd3b2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2	0.073	Rat
Mcl1	myeloid cell leukemia sequence 1	0.073
Cdk6	cyclin-dependent kinase 6	0.073
Flt1	FMS-like tyrosine kinase 1	0.073	Fly
Cps1	carbamoyl-phosphate synthetase 1	0.073
Pcdh12	protocadherin 12	0.072
Hivep2	human immunodeficiency virus type I enhancer binding protein 2	0.072
Agrp	agouti related protein	0.072
Foxk1	forkhead box K1	0.072
F9	coagulation factor IX	0.071
Dok2	docking protein 2	0.071
Gnao1	guanine nucleotide binding protein, alpha O	0.071
Stab1	stabilin 1	0.071
Serping1	serine (or cysteine) peptidase inhibitor, clade G, member 1	0.070
Itga3	integrin alpha 3	0.070
Ptpra	protein tyrosine phosphatase, receptor type, A	0.070
Smyd1	SET and MYND domain containing 1	0.070
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.070
Ubc	ubiquitin C	0.069
Il4ra	interleukin 4 receptor, alpha	0.069
Fabp4	fatty acid binding protein 4, adipocyte	0.069
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.069
Cdh5	cadherin 5	0.068
Mdm2	transformed mouse 3T3 cell double minute 2	0.068
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.068
Pkd2	polycystic kidney disease 2	0.068
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.068
Fzd4	frizzled homolog 4 (Drosophila)	0.068
Gm4788	predicted gene 4788	0.068
Rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.068
Mybpc3	myosin binding protein C, cardiac	0.067
Adm	adrenomedullin	0.067
Il1r1	interleukin 1 receptor, type I	0.067
Nr1h4	nuclear receptor subfamily 1, group H, member 4	0.066	Mouse
Stat5b	signal transducer and activator of transcription 5B	0.066
a	nonagouti	0.066
Npy5r	neuropeptide Y receptor Y5	0.066
Fbxl20	F-box and leucine-rich repeat protein 20	0.065
Zfp865	zinc finger protein 865	0.065
Cyp4b1	cytochrome P450, family 4, subfamily b, polypeptide 1	0.065
Eda	ectodysplasin-A	0.065
Pag1	phosphoprotein associated with glycosphingolipid microdomains 1	0.065
Ankrd17	ankyrin repeat domain 17	0.065
Gys1	glycogen synthase 1, muscle	0.064
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.064
Fxr1	fragile X mental retardation gene 1, autosomal homolog	0.064	Fly
Rxra	retinoid X receptor alpha	0.064	Rat
Phlpp1	PH domain and leucine rich repeat protein phosphatase 1	0.064
Aloxe3	arachidonate lipoxygenase 3	0.064
Tacr2	tachykinin receptor 2	0.064
Igf2r	insulin-like growth factor 2 receptor	0.063
Aqp8	aquaporin 8	0.063
Hp	haptoglobin	0.063
Rasip1	Ras interacting protein 1	0.063
Mup5	major urinary protein 5	0.062	Mouse
Ank	progressive ankylosis	0.062
Tcra	T-cell receptor alpha chain	0.062
Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	0.062
Ctnnd1	catenin (cadherin associated protein), delta 1	0.062
Pvr	poliovirus receptor	0.062
Cd19	CD19 antigen	0.062
Cxcl2	chemokine (C-X-C motif) ligand 2	0.062
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.061
Fbxw7	F-box and WD-40 domain protein 7	0.061
Ppy	pancreatic polypeptide	0.061
Egr2	early growth response 2	0.061	Mouse Rat
Pim2	proviral integration site 2	0.061
Fgg	fibrinogen gamma chain	0.061
Slc16a11	solute carrier family 16 (monocarboxylic acid transporters), member 11	0.060
Slc27a3	solute carrier family 27 (fatty acid transporter), member 3	0.060	Mouse
Htr2c	5-hydroxytryptamine (serotonin) receptor 2C	0.060
Slc12a1	solute carrier family 12, member 1	0.060
Adipor2	adiponectin receptor 2	0.060
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.060
Gpx3	glutathione peroxidase 3	0.060
Dhcr7	7-dehydrocholesterol reductase	0.060
Adra2c	adrenergic receptor, alpha 2c	0.060
Hif3a	hypoxia inducible factor 3, alpha subunit	0.059	Fly
Hmox1	heme oxygenase (decycling) 1	0.059
Galr1	galanin receptor 1	0.059
Dyrk1b	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b	0.059
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.059
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.059
Fgf11	fibroblast growth factor 11	0.059
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.059
Serpina12	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12	0.059
Egr1	early growth response 1	0.058
Htr1d	5-hydroxytryptamine (serotonin) receptor 1D	0.058
Map2k7	mitogen-activated protein kinase kinase 7	0.058
Cd70	CD70 antigen	0.058
Mef2d	myocyte enhancer factor 2D	0.058
Fcgr3	Fc receptor, IgG, low affinity III	0.057
Abcc6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	0.057
Phox2b	paired-like homeobox 2b	0.057
Aatk	apoptosis-associated tyrosine kinase	0.057
Apoc3	apolipoprotein C-III	0.057
Mprip	myosin phosphatase Rho interacting protein	0.057
Serpina1b	serine (or cysteine) preptidase inhibitor, clade A, member 1B	0.057	Mouse
Amh	anti-Mullerian hormone	0.057
Lcat	lecithin cholesterol acyltransferase	0.057
Mxd1	MAX dimerization protein 1	0.057
Ifna5	interferon alpha 5	0.057
Creb1	cAMP responsive element binding protein 1	0.057
Egr3	early growth response 3	0.056	Mouse
Orm3	orosomucoid 3	0.056
Znrf4	zinc and ring finger 4	0.056
Ulk2	Unc-51 like kinase 2 (C. elegans)	0.056
Mup3	major urinary protein 3	0.056	Mouse
Itih1	inter-alpha trypsin inhibitor, heavy chain 1	0.056
Tlr2	toll-like receptor 2	0.056
Tspyl1	testis-specific protein, Y-encoded-like 1	0.056
Pdyn	prodynorphin	0.056
Agpat1	1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)	0.056
Pdx1	pancreatic and duodenal homeobox 1	0.055
Plekho2	pleckstrin homology domain containing, family O member 2	0.055
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.055
Syt2	synaptotagmin II	0.055
Ptprn2	protein tyrosine phosphatase, receptor type, N polypeptide 2	0.055
Vil1	villin 1	0.055
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.055
Ccne1	cyclin E1	0.055
Fgf8	fibroblast growth factor 8	0.055
Prodh2	proline dehydrogenase (oxidase) 2	0.055
Chrna7	cholinergic receptor, nicotinic, alpha polypeptide 7	0.055
Bcl2	B-cell leukemia/lymphoma 2	0.055	Rat
Plg	plasminogen	0.055
Lyst	lysosomal trafficking regulator	0.055
Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	0.055
Lama5	laminin, alpha 5	0.055
Ghrh	growth hormone releasing hormone	0.055
Mertk	c-mer proto-oncogene tyrosine kinase	0.055
Hs1bp3	HCLS1 binding protein 3	0.054
Cyp4a10	cytochrome P450, family 4, subfamily a, polypeptide 10	0.054
Plxna1	plexin A1	0.054
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.054
Bdkrb2	bradykinin receptor, beta 2	0.054
Barx1	BarH-like homeobox 1	0.054
Cyp2d10	cytochrome P450, family 2, subfamily d, polypeptide 10	0.054
Ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.054
5430411K18Rik	RIKEN cDNA 5430411K18 gene	0.054
Hand1	heart and neural crest derivatives expressed transcript 1	0.054
Adra1b	adrenergic receptor, alpha 1b	0.054
Cxcl1	chemokine (C-X-C motif) ligand 1	0.054
Fga	fibrinogen alpha chain	0.054
Atoh7	atonal homolog 7 (Drosophila)	0.053
Pdk2	pyruvate dehydrogenase kinase, isoenzyme 2	0.053
Egln3	EGL nine homolog 3 (C. elegans)	0.053
Kcnj6	potassium inwardly-rectifying channel, subfamily J, member 6	0.053
Cdk18	cyclin-dependent kinase 18	0.053
Fgfr1	fibroblast growth factor receptor 1	0.053
Fosl2	fos-like antigen 2	0.053
Smad5	MAD homolog 5 (Drosophila)	0.053
Nr1i3	nuclear receptor subfamily 1, group I, member 3	0.053	Mouse
Stam	signal transducing adaptor molecule (SH3 domain and ITAM motif) 1	0.053
Cep170	centrosomal protein 170	0.052
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.052
Pdgfb	platelet derived growth factor, B polypeptide	0.052
Hand2	heart and neural crest derivatives expressed transcript 2	0.052
Serpina5	serine (or cysteine) peptidase inhibitor, clade A, member 5	0.052	Mouse
D4Wsu53e	DNA segment, Chr 4, Wayne State University 53, expressed	0.052
Srf	serum response factor	0.052
Star	steroidogenic acute regulatory protein	0.052
Serpina1a	serine (or cysteine) peptidase inhibitor, clade A, member 1A	0.052	Mouse
Plin4	perilipin 4	0.052
Vegfc	vascular endothelial growth factor C	0.052
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.052
Akt2	thymoma viral proto-oncogene 2	0.051
Hnf4a	hepatic nuclear factor 4, alpha	0.051
C4b	complement component 4B (Childo blood group)	0.051
E2f1	E2F transcription factor 1	0.051
Slc6a12	solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12	0.051
Hamp	hepcidin antimicrobial peptide	0.051
Kif1b	kinesin family member 1B	0.051
Phf1	PHD finger protein 1	0.051
Socs3	suppressor of cytokine signaling 3	0.051
Sry	sex determining region of Chr Y	0.051
Klc2	kinesin light chain 2	0.051
Tmem176b	transmembrane protein 176B	0.050
Gab1	growth factor receptor bound protein 2-associated protein 1	0.050
Adig	adipogenin	0.050
Afm	afamin	0.050
Atg2a	ATG2 autophagy related 2 homolog A (S. cerevisiae)	0.050
Doc2b	double C2, beta	0.050
Selp	selectin, platelet	0.050
Ccrl2	chemokine (C-C motif) receptor-like 2	0.050
A530016L24Rik	RIKEN cDNA A530016L24 gene	0.050
Ccnd1	cyclin D1	0.050
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.049
Slc22a17	solute carrier family 22 (organic cation transporter), member 17	0.049
Hcls1	hematopoietic cell specific Lyn substrate 1	0.049
Kif1a	kinesin family member 1A	0.049
Akr1c21	aldo-keto reductase family 1, member C21	0.049
Gcgr	glucagon receptor	0.049	Mouse
Fgfr2	fibroblast growth factor receptor 2	0.049
Azgp1	alpha-2-glycoprotein 1, zinc	0.049
Spp1	secreted phosphoprotein 1	0.049
Oprk1	opioid receptor, kappa 1	0.049
Src	Rous sarcoma oncogene	0.049	Rat
Arf3	ADP-ribosylation factor 3	0.049
Fto	fat mass and obesity associated	0.048
Cdh6	cadherin 6	0.048
Crp	C-reactive protein, pentraxin-related	0.048
Tubb4	tubulin, beta 4	0.048
Fxyd7	FXYD domain-containing ion transport regulator 7	0.048
Nradd	neurotrophin receptor associated death domain	0.048
Pgf	placental growth factor	0.048
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.048
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.048
Atp2a3	ATPase, Ca++ transporting, ubiquitous	0.048
Hmgcs2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2	0.048
Stk10	serine/threonine kinase 10	0.048
Lrrc8c	leucine rich repeat containing 8 family, member C	0.048
Fgfr3	fibroblast growth factor receptor 3	0.048
Clk4	CDC like kinase 4	0.048
Stxbp3a	syntaxin binding protein 3A	0.048
Hc	hemolytic complement	0.048
Grb7	growth factor receptor bound protein 7	0.048	Mouse
Ccl2	chemokine (C-C motif) ligand 2	0.047
Clrn3	clarin 3	0.047
Lmna	lamin A	0.047
Zbtb7a	zinc finger and BTB domain containing 7a	0.047
P2rx1	purinergic receptor P2X, ligand-gated ion channel, 1	0.047
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.047	Rat
Khdrbs1	KH domain containing, RNA binding, signal transduction associated 1	0.047
Arl10	ADP-ribosylation factor-like 10	0.047
Gjb5	gap junction protein, beta 5	0.047
Homer1	homer homolog 1 (Drosophila)	0.047
Gabrg3	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3	0.047
A930001N09Rik	RIKEN cDNA A930001N09 gene	0.047
Runx1	runt related transcription factor 1	0.047
Guca2b	guanylate cyclase activator 2b (retina)	0.047
Fzd8	frizzled homolog 8 (Drosophila)	0.047
Stx1a	syntaxin 1A (brain)	0.047	Worm
Bmi1	Bmi1 polycomb ring finger oncogene	0.046
Socs1	suppressor of cytokine signaling 1	0.046
Serpind1	serine (or cysteine) peptidase inhibitor, clade D, member 1	0.046
Cdk5r2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.046
Hbegf	heparin-binding EGF-like growth factor	0.046
Spry2	sprouty homolog 2 (Drosophila)	0.046
Gnrh1	gonadotropin releasing hormone 1	0.046
Clk1	CDC-like kinase 1	0.046
Barhl1	BarH-like 1 (Drosophila)	0.046
Megf8	multiple EGF-like-domains 8	0.046
Hgs	HGF-regulated tyrosine kinase substrate	0.046
Car3	carbonic anhydrase 3	0.046
Il5	interleukin 5	0.046
Pgr	progesterone receptor	0.046
Ldoc1l	leucine zipper, down-regulated in cancer 1-like	0.046
Osmr	oncostatin M receptor	0.046
Adh4	alcohol dehydrogenase 4 (class II), pi polypeptide	0.045
Apoa4	apolipoprotein A-IV	0.045
Flcn	folliculin	0.045
Nnat	neuronatin	0.045
Nhlh2	nescient helix loop helix 2	0.045
Entpd1	ectonucleoside triphosphate diphosphohydrolase 1	0.045
Mib1	mindbomb homolog 1 (Drosophila)	0.045
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.045	Mouse
Wbp2	WW domain binding protein 2	0.045
Cd47	CD47 antigen (Rh-related antigen, integrin-associated signal transducer)	0.045
Hipk3	homeodomain interacting protein kinase 3	0.045
Klk1b21	kallikrein 1-related peptidase b21	0.045
Itga6	integrin alpha 6	0.045
Dvl2	dishevelled 2, dsh homolog (Drosophila)	0.045
Pbx3	pre B-cell leukemia transcription factor 3	0.045
Lpl	lipoprotein lipase	0.045
Nedd4	neural precursor cell expressed, developmentally down-regulated 4	0.045
Fcho1	FCH domain only 1	0.044
Irf2bp1	interferon regulatory factor 2 binding protein 1	0.044
Efs	embryonal Fyn-associated substrate	0.044
Gpr182	G protein-coupled receptor 182	0.044
Inca1	inhibitor of CDK, cyclin A1 interacting protein 1	0.044
Wdtc1	WD and tetratricopeptide repeats 1	0.044
Il1b	interleukin 1 beta	0.044
Lrg1	leucine-rich alpha-2-glycoprotein 1	0.044
Gstm3	glutathione S-transferase, mu 3	0.044
Bcl3	B-cell leukemia/lymphoma 3	0.044
Ephx2	epoxide hydrolase 2, cytoplasmic	0.044
Thpo	thrombopoietin	0.044
Adam9	a disintegrin and metallopeptidase domain 9 (meltrin gamma)	0.044
Cd68	CD68 antigen	0.044
Ch25h	cholesterol 25-hydroxylase	0.044
Rora	RAR-related orphan receptor alpha	0.044
Abcc5	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	0.044	Rat
Bcl6	B-cell leukemia/lymphoma 6	0.044
Fabp1	fatty acid binding protein 1, liver	0.044
Rnf208	ring finger protein 208	0.044
Samd4b	sterile alpha motif domain containing 4B	0.044
C1qtnf5	C1q and tumor necrosis factor related protein 5	0.044	Mouse
Slc6a9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	0.044
Casp9	caspase 9	0.043
Rhbdf1	rhomboid family 1 (Drosophila)	0.043
Cyp2a12	cytochrome P450, family 2, subfamily a, polypeptide 12	0.043
Ccl12	chemokine (C-C motif) ligand 12	0.043
Ncoa2	nuclear receptor coactivator 2	0.043
Nr4a2	nuclear receptor subfamily 4, group A, member 2	0.043
Oxt	oxytocin	0.043
Ccl9	chemokine (C-C motif) ligand 9	0.043
Aak1	AP2 associated kinase 1	0.043
Kcnj3	potassium inwardly-rectifying channel, subfamily J, member 3	0.043
F8	coagulation factor VIII	0.043
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.043
Sntb1	syntrophin, basic 1	0.043
Npr2	natriuretic peptide receptor 2	0.043
Adcy6	adenylate cyclase 6	0.042
Fgb	fibrinogen beta chain	0.042
Lect2	leukocyte cell-derived chemotaxin 2	0.042
Ralgds	ral guanine nucleotide dissociation stimulator	0.042
Pklr	pyruvate kinase liver and red blood cell	0.042
Ephb6	Eph receptor B6	0.042
Map4k2	mitogen-activated protein kinase kinase kinase kinase 2	0.042	Fly
Zfp398	zinc finger protein 398	0.042
Sphk2	sphingosine kinase 2	0.042
Retn	resistin	0.042
Fosb	FBJ osteosarcoma oncogene B	0.042
Scd1	stearoyl-Coenzyme A desaturase 1	0.042
Thbd	thrombomodulin	0.042
Plcd1	phospholipase C, delta 1	0.042
Rpe65	retinal pigment epithelium 65	0.042
Gp5	glycoprotein 5 (platelet)	0.042
Fmr1	fragile X mental retardation syndrome 1 homolog	0.042	Fly
Prkcz	protein kinase C, zeta	0.042	Human Mouse Rat
Klk6	kallikrein related-peptidase 6	0.042
Il1r2	interleukin 1 receptor, type II	0.042
Prl3a1	prolactin family 3, subfamily a, member 1	0.042
Fgf13	fibroblast growth factor 13	0.042
Hpd	4-hydroxyphenylpyruvic acid dioxygenase	0.042
Rorc	RAR-related orphan receptor gamma	0.042
Crb2	crumbs homolog 2 (Drosophila)	0.042
Dlx4	distal-less homeobox 4	0.041
Aldob	aldolase B, fructose-bisphosphate	0.041	Rat
Cd28	CD28 antigen	0.041
Vcl	vinculin	0.041
Hcn2	hyperpolarization-activated, cyclic nucleotide-gated K+ 2	0.041
Nsf	N-ethylmaleimide sensitive fusion protein	0.041
Sema7a	sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A	0.041
Bcan	brevican	0.041
Rptor	regulatory associated protein of MTOR, complex 1	0.041
Mcm9	minichromosome maintenance complex component 9	0.041
Ptpn5	protein tyrosine phosphatase, non-receptor type 5	0.041
Slc25a48	solute carrier family 25, member 48	0.041
Tinagl1	tubulointerstitial nephritis antigen-like 1	0.041
Prkci	protein kinase C, iota	0.041
F2	coagulation factor II	0.041
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.040	Mouse
Nrp1	neuropilin 1	0.040
Jag2	jagged 2	0.040
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.040
Pdlim7	PDZ and LIM domain 7	0.040
Cd247	CD247 antigen	0.040
Stim1	stromal interaction molecule 1	0.040
Atf1	activating transcription factor 1	0.040
Gata6	GATA binding protein 6	0.040
Notch1	Notch gene homolog 1 (Drosophila)	0.040
Gpr37	G protein-coupled receptor 37	0.040
Ccl7	chemokine (C-C motif) ligand 7	0.040
E2f3	E2F transcription factor 3	0.040
Hbb-bh1	hemoglobin Z, beta-like embryonic chain	0.040
Cd44	CD44 antigen	0.040
Aff4	AF4/FMR2 family, member 4	0.039
Cp	ceruloplasmin	0.039
Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like	0.039
Tnf	tumor necrosis factor	0.039
F2r	coagulation factor II (thrombin) receptor	0.039	Mouse
Cyp2d26	cytochrome P450, family 2, subfamily d, polypeptide 26	0.039
Utf1	undifferentiated embryonic cell transcription factor 1	0.039
Txnip	thioredoxin interacting protein	0.039
Trf	transferrin	0.039
Rapgef3	Rap guanine nucleotide exchange factor (GEF) 3	0.039
Zfr2	zinc finger RNA binding protein 2	0.039
Ptprf	protein tyrosine phosphatase, receptor type, F	0.039	Rat
Ext1	exostoses (multiple) 1	0.039
Clcn6	chloride channel 6	0.039
Ccr1l1	chemokine (C-C motif) receptor 1-like 1	0.039
Sardh	sarcosine dehydrogenase	0.039
Foxo3	forkhead box O3	0.039	Mouse Worm Fly
Rasgrp2	RAS, guanyl releasing protein 2	0.039
Uts2r	urotensin 2 receptor	0.039
Krt36	keratin 36	0.038
Rab27a	RAB27A, member RAS oncogene family	0.038
Kcnk10	potassium channel, subfamily K, member 10	0.038
Prss28	protease, serine, 28	0.038
Acvr2b	activin receptor IIB	0.038
Itgav	integrin alpha V	0.038
Ramp2	receptor (calcitonin) activity modifying protein 2	0.038
Ip6k1	inositol hexaphosphate kinase 1	0.038
Ifnb1	interferon beta 1, fibroblast	0.038
Mgp	matrix Gla protein	0.038	Mouse
Plac1	placental specific protein 1	0.038
Rragc	Ras-related GTP binding C	0.038
Gh	growth hormone	0.038
Rhoc	ras homolog gene family, member C	0.038
Col4a1	collagen, type IV, alpha 1	0.038
Hcrt	hypocretin	0.038
Usp22	ubiquitin specific peptidase 22	0.038
Sod3	superoxide dismutase 3, extracellular	0.038
Abcd1	ATP-binding cassette, sub-family D (ALD), member 1	0.038
Cyp2d9	cytochrome P450, family 2, subfamily d, polypeptide 9	0.038
Cidea	cell death-inducing DNA fragmentation factor, alpha subunit-like effector A	0.038
Large	like-glycosyltransferase	0.038
Tgm2	transglutaminase 2, C polypeptide	0.038
Il6st	interleukin 6 signal transducer	0.038
Dnm2	dynamin 2	0.038
Sort1	sortilin 1	0.038
Zfp36l2	zinc finger protein 36, C3H type-like 2	0.038
Igfbp3	insulin-like growth factor binding protein 3	0.038
Kctd20	potassium channel tetramerisation domain containing 20	0.038
Zbtb7b	zinc finger and BTB domain containing 7B	0.038
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.038
Foxf1a	forkhead box F1a	0.038
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.038	Rat
Prp2	proline rich protein 2	0.038
Icam1	intercellular adhesion molecule 1	0.038
Csn1s2b	casein alpha s2-like B	0.037
Skil	SKI-like	0.037
Pdpn	podoplanin	0.037
St8sia5	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5	0.037
Hlx	H2.0-like homeobox	0.037
Elovl3	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3	0.037
Grpr	gastrin releasing peptide receptor	0.037
Ctdsp2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2	0.037
Irak4	interleukin-1 receptor-associated kinase 4	0.037
Tmem204	transmembrane protein 204	0.037
Ptprs	protein tyrosine phosphatase, receptor type, S	0.037
Il12a	interleukin 12a	0.037
Chrna6	cholinergic receptor, nicotinic, alpha polypeptide 6	0.037
Gnrhr	gonadotropin releasing hormone receptor	0.037
Esam	endothelial cell-specific adhesion molecule	0.037
Umod	uromodulin	0.037
Mgat3	mannoside acetylglucosaminyltransferase 3	0.037
Gem	GTP binding protein (gene overexpressed in skeletal muscle)	0.037
Wwox	WW domain-containing oxidoreductase	0.037
Mpp2	membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)	0.037
Tead4	TEA domain family member 4	0.037
Cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	0.037
Gstm1	glutathione S-transferase, mu 1	0.037
Zfand5	zinc finger, AN1-type domain 5	0.037
Atoh8	atonal homolog 8 (Drosophila)	0.037
Flt3l	FMS-like tyrosine kinase 3 ligand	0.036
Sox17	SRY-box containing gene 17	0.036
Rel	reticuloendotheliosis oncogene	0.036
Mknk1	MAP kinase-interacting serine/threonine kinase 1	0.036
Sema4d	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	0.036
Elf4	E74-like factor 4 (ets domain transcription factor)	0.036
Ikbkap	inhibitor of kappa light polypeptide enhancer in B-cells, kinase complex-associated protein	0.036
Mpl	myeloproliferative leukemia virus oncogene	0.036
Itga5	integrin alpha 5 (fibronectin receptor alpha)	0.036
Map4k4	mitogen-activated protein kinase kinase kinase kinase 4	0.036
Ly6h	lymphocyte antigen 6 complex, locus H	0.036
Ninj2	ninjurin 2	0.036
Rag1	recombination activating gene 1	0.036
Dlk1	delta-like 1 homolog (Drosophila)	0.036
Slc29a4	solute carrier family 29 (nucleoside transporters), member 4	0.036
Npr3	natriuretic peptide receptor 3	0.036
Matk	megakaryocyte-associated tyrosine kinase	0.036
Ndrg1	N-myc downstream regulated gene 1	0.036
Pde4b	phosphodiesterase 4B, cAMP specific	0.036
Angptl4	angiopoietin-like 4	0.036
Avp	arginine vasopressin	0.036
Cd93	CD93 antigen	0.036
Syt17	synaptotagmin XVII	0.036
Pde3a	phosphodiesterase 3A, cGMP inhibited	0.036	Mouse
Rac1	RAS-related C3 botulinum substrate 1	0.036
Cyp3a11	cytochrome P450, family 3, subfamily a, polypeptide 11	0.036
Zeb1	zinc finger E-box binding homeobox 1	0.036
Tgfbi	transforming growth factor, beta induced	0.036
Sav1	salvador homolog 1 (Drosophila)	0.036
Lama4	laminin, alpha 4	0.036
Ager	advanced glycosylation end product-specific receptor	0.036
Ptprb	protein tyrosine phosphatase, receptor type, B	0.036
Wnk2	WNK lysine deficient protein kinase 2	0.036
Icam5	intercellular adhesion molecule 5, telencephalin	0.035
Tph1	tryptophan hydroxylase 1	0.035
Stk40	serine/threonine kinase 40	0.035	Mouse
Stxbp1	syntaxin binding protein 1	0.035	Mouse
Rdh7	retinol dehydrogenase 7	0.035
Tenc1	tensin like C1 domain-containing phosphatase	0.035