IMP: Integrative Multi-species Prediction

Mus musculus

58 genes annotated in mouse

response to hypoxia

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to hypoxia"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "response to hypoxia" (in gray)

Name	Description	Probability	Func Analog Organism
Vegfa	vascular endothelial growth factor A	0.997	Human
Nos3	nitric oxide synthase 3, endothelial cell	0.994	Mouse Rat
Trp53	transformation related protein 53	0.991	Human Zebrafish Worm
Pten	phosphatase and tensin homolog	0.990
Tgfbr2	transforming growth factor, beta receptor II	0.930	Rat
Ldb3	LIM domain binding 3	0.924
Mmp9	matrix metallopeptidase 9	0.906	Mouse Rat
Csf1	colony stimulating factor 1 (macrophage)	0.890
Ptgs2	prostaglandin-endoperoxide synthase 2	0.883	Human
Fas	Fas (TNF receptor superfamily member 6)	0.849	Rat
Cd44	CD44 antigen	0.848
Cav1	caveolin 1, caveolae protein	0.790
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.782
Ece1	endothelin converting enzyme 1	0.731	Rat
Notch2	Notch gene homolog 2 (Drosophila)	0.723	Mouse
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.685	Human
Nos1	nitric oxide synthase 1, neuronal	0.652	Human Mouse Rat
Nos2	nitric oxide synthase 2, inducible	0.649
Fbn1	fibrillin 1	0.619
Epas1	endothelial PAS domain protein 1	0.572
Clock	circadian locomotor output cycles kaput	0.560
Mdm2	transformed mouse 3T3 cell double minute 2	0.549	Human
Trp73	transformation related protein 73	0.536	Worm
Bcl2	B-cell leukemia/lymphoma 2	0.535
Tpi1	triosephosphate isomerase 1	0.529
Lepr	leptin receptor	0.528
Ank1	ankyrin 1, erythroid	0.487
Mcl1	myeloid cell leukemia sequence 1	0.483	Mouse
Kl	klotho	0.479
Hif1a	hypoxia inducible factor 1, alpha subunit	0.455
Neurl1a	neuralized homolog 1A (Drosophila)	0.440
Ren1	renin 1 structural	0.428
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.428
Pparg	peroxisome proliferator activated receptor gamma	0.415	Mouse
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.409
Apoe	apolipoprotein E	0.408
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.400
Acvrl1	activin A receptor, type II-like 1	0.398
Ccl2	chemokine (C-C motif) ligand 2	0.389
Egln1	EGL nine homolog 1 (C. elegans)	0.388	Human Rat Worm Fly
Rb1	retinoblastoma 1	0.375
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.367
Skil	SKI-like	0.367
Flt1	FMS-like tyrosine kinase 1	0.358
Prkcc	protein kinase C, gamma	0.355
Ednra	endothelin receptor type A	0.348
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.330
Insr	insulin receptor	0.326
Ahr	aryl-hydrocarbon receptor	0.317
Tgfb1	transforming growth factor, beta 1	0.316	Rat
Il10	interleukin 10	0.299
Prrx1	paired related homeobox 1	0.295
Egfl7	EGF-like domain 7	0.294
Agtr1a	angiotensin II receptor, type 1a	0.290
Igh	immunoglobulin heavy chain complex	0.282
Stat5a	signal transducer and activator of transcription 5A	0.281
Vhl	von Hippel-Lindau tumor suppressor	0.281	Human Worm Fly
Tlr4	toll-like receptor 4	0.277	Rat
Gapdh	glyceraldehyde-3-phosphate dehydrogenase	0.274
Lyz2	lysozyme 2	0.259
Gata6	GATA binding protein 6	0.257	Human
Uqcrc1	ubiquinol-cytochrome c reductase core protein 1	0.256
Chrna3	cholinergic receptor, nicotinic, alpha polypeptide 3	0.256	Mouse
Bax	BCL2-associated X protein	0.244	Mouse
Nf1	neurofibromatosis 1	0.243
Gdnf	glial cell line derived neurotrophic factor	0.241
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.241
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.229
Ptgfr	prostaglandin F receptor	0.227
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.224
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.215
Canx	calnexin	0.211
Kdr	kinase insert domain protein receptor	0.211	Mouse
Chrnb4	cholinergic receptor, nicotinic, beta polypeptide 4	0.207	Mouse
Chrnb2	cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)	0.202
F2	coagulation factor II	0.202
Wisp2	WNT1 inducible signaling pathway protein 2	0.200
Emx1	empty spiracles homolog 1 (Drosophila)	0.199
Hdac1	histone deacetylase 1	0.198
Gypa	glycophorin A	0.197
Gata4	GATA binding protein 4	0.197
Fzd4	frizzled homolog 4 (Drosophila)	0.192
Tgfbr3	transforming growth factor, beta receptor III	0.190	Rat
Dll1	delta-like 1 (Drosophila)	0.182
Gnrh1	gonadotropin releasing hormone 1	0.179
Tgfb2	transforming growth factor, beta 2	0.178	Human
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.178	Mouse
Stat6	signal transducer and activator of transcription 6	0.174
Prkce	protein kinase C, epsilon	0.173
Kcnj6	potassium inwardly-rectifying channel, subfamily J, member 6	0.172
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.168
Egfr	epidermal growth factor receptor	0.166
Epor	erythropoietin receptor	0.166
Bmp4	bone morphogenetic protein 4	0.158	Mouse
Meox1	mesenchyme homeobox 1	0.154
Acvr1	activin A receptor, type 1	0.153
Dab1	disabled homolog 1 (Drosophila)	0.151
Tgfbr1	transforming growth factor, beta receptor I	0.150	Rat
Fgf8	fibroblast growth factor 8	0.150
Selp	selectin, platelet	0.148
Mdm4	transformed mouse 3T3 cell double minute 4	0.146	Human
Fgfr2	fibroblast growth factor receptor 2	0.146
Ltbp2	latent transforming growth factor beta binding protein 2	0.146
Onecut1	one cut domain, family member 1	0.145
Cyr61	cysteine rich protein 61	0.145
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.144
Hif3a	hypoxia inducible factor 3, alpha subunit	0.143
Ar	androgen receptor	0.142
Inpp5d	inositol polyphosphate-5-phosphatase D	0.141
Upk3b	uroplakin 3B	0.140
Plcg1	phospholipase C, gamma 1	0.140
Nkx3-1	NK-3 transcription factor, locus 1 (Drosophila)	0.140	Human
Gm5506	predicted gene 5506	0.136
Smad3	MAD homolog 3 (Drosophila)	0.135	Human
Notch1	Notch gene homolog 1 (Drosophila)	0.135
Thbs1	thrombospondin 1	0.135
Otp	orthopedia homolog (Drosophila)	0.134
Apoh	apolipoprotein H	0.133
Stat3	signal transducer and activator of transcription 3	0.132
Sfpi1	SFFV proviral integration 1	0.131
Lhx6	LIM homeobox protein 6	0.129
Plau	plasminogen activator, urokinase	0.129
Ncoa3	nuclear receptor coactivator 3	0.128
Rbl1	retinoblastoma-like 1 (p107)	0.127
Cyc1	cytochrome c-1	0.126
Kcnk3	potassium channel, subfamily K, member 3	0.123
Kcnj3	potassium inwardly-rectifying channel, subfamily J, member 3	0.118
Yap1	yes-associated protein 1	0.115
Cdh5	cadherin 5	0.114
Rara	retinoic acid receptor, alpha	0.113
Lox	lysyl oxidase	0.111
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.111
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.109	Mouse
Dok1	docking protein 1	0.109
Esr1	estrogen receptor 1 (alpha)	0.106
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.105	Zebrafish Rat
Cryab	crystallin, alpha B	0.104
Has1	hyaluronan synthase1	0.104
Vegfc	vascular endothelial growth factor C	0.104
Irs2	insulin receptor substrate 2	0.104
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.103
Ltbp1	latent transforming growth factor beta binding protein 1	0.100
Dcx	doublecortin	0.100
Zeb1	zinc finger E-box binding homeobox 1	0.099
Cd151	CD151 antigen	0.099
Edn1	endothelin 1	0.099
Ghr	growth hormone receptor	0.098
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.098
Htra3	HtrA serine peptidase 3	0.098
E2f1	E2F transcription factor 1	0.097
Mmp2	matrix metallopeptidase 2	0.096
Met	met proto-oncogene	0.096
Col4a3	collagen, type IV, alpha 3	0.096
Figf	c-fos induced growth factor	0.095	Rat
Tjp1	tight junction protein 1	0.094
Kiss1	KiSS-1 metastasis-suppressor	0.094
Ctnnb1	catenin (cadherin associated protein), beta 1	0.093
Pnpla2	patatin-like phospholipase domain containing 2	0.093
Alx3	aristaless-like homeobox 3	0.093
Apc	adenomatosis polyposis coli	0.093
Il1r1	interleukin 1 receptor, type I	0.092
Scn1b	sodium channel, voltage-gated, type I, beta	0.090
Edn2	endothelin 2	0.090	Mouse
Daxx	Fas death domain-associated protein	0.090
Smo	smoothened homolog (Drosophila)	0.089
Apob	apolipoprotein B	0.089
Fgf4	fibroblast growth factor 4	0.089
Il6	interleukin 6	0.088
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.088
Il18	interleukin 18	0.088
Slc40a1	solute carrier family 40 (iron-regulated transporter), member 1	0.087
Bdkrb2	bradykinin receptor, beta 2	0.086
Nodal	nodal	0.086
Pzp	pregnancy zone protein	0.085
Myod1	myogenic differentiation 1	0.084
Myc	myelocytomatosis oncogene	0.084
Ikzf1	IKAROS family zinc finger 1	0.083
Srebf2	sterol regulatory element binding factor 2	0.083
Hbb-b1	hemoglobin, beta adult major chain	0.083
Hras1	Harvey rat sarcoma virus oncogene 1	0.082
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.082
Spp1	secreted phosphoprotein 1	0.082
Actn2	actinin alpha 2	0.082
Sox17	SRY-box containing gene 17	0.081
Irf8	interferon regulatory factor 8	0.081
Gck	glucokinase	0.080
Ednrb	endothelin receptor type B	0.080	Mouse
Fgfr1	fibroblast growth factor receptor 1	0.080
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.080
Timp3	tissue inhibitor of metalloproteinase 3	0.080
Glra1	glycine receptor, alpha 1 subunit	0.079
Foxf1a	forkhead box F1a	0.079
Myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.079
Egr1	early growth response 1	0.078
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.078
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.078
Fosb	FBJ osteosarcoma oncogene B	0.077
Wnt6	wingless-related MMTV integration site 6	0.076
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.076
Timp1	tissue inhibitor of metalloproteinase 1	0.075
Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.074
Osmr	oncostatin M receptor	0.074
Lhx3	LIM homeobox protein 3	0.074
Foxo1	forkhead box O1	0.074
Itih1	inter-alpha trypsin inhibitor, heavy chain 1	0.074
Slc27a5	solute carrier family 27 (fatty acid transporter), member 5	0.073
Tcf21	transcription factor 21	0.073
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.073	Mouse
Gpr3	G-protein coupled receptor 3	0.073
Foxc2	forkhead box C2	0.073
Casq2	calsequestrin 2	0.072
Il6st	interleukin 6 signal transducer	0.072
Lep	leptin	0.072
Ptprb	protein tyrosine phosphatase, receptor type, B	0.071
Casp12	caspase 12	0.071	Mouse
Bak1	BCL2-antagonist/killer 1	0.071	Mouse
Ryr3	ryanodine receptor 3	0.070	Mouse
Gja1	gap junction protein, alpha 1	0.070
Smad1	MAD homolog 1 (Drosophila)	0.070
Ltbp3	latent transforming growth factor beta binding protein 3	0.070
Grm1	glutamate receptor, metabotropic 1	0.070
Cyp2d10	cytochrome P450, family 2, subfamily d, polypeptide 10	0.068
Mab21l2	mab-21-like 2 (C. elegans)	0.067
Cry1	cryptochrome 1 (photolyase-like)	0.067
Lama5	laminin, alpha 5	0.067
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.067
Aloxe3	arachidonate lipoxygenase 3	0.067
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.067	Mouse
Ep300	E1A binding protein p300	0.067	Human
Car5a	carbonic anhydrase 5a, mitochondrial	0.067
Cd36	CD36 antigen	0.066
Guca2b	guanylate cyclase activator 2b (retina)	0.066
Hspb7	heat shock protein family, member 7 (cardiovascular)	0.066
Anln	anillin, actin binding protein	0.065
Bcl3	B-cell leukemia/lymphoma 3	0.065
Irf1	interferon regulatory factor 1	0.065
Dab2	disabled homolog 2 (Drosophila)	0.064
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.064
Wnk4	WNK lysine deficient protein kinase 4	0.063
Bcl6	B-cell leukemia/lymphoma 6	0.063
Ccbp2	chemokine binding protein 2	0.063
Tnnt2	troponin T2, cardiac	0.062
Hrh1	histamine receptor H1	0.062
Popdc3	popeye domain containing 3	0.062
Tat	tyrosine aminotransferase	0.062
Ldlr	low density lipoprotein receptor	0.062	Rat
Pde6b	phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide	0.061
Dlx6	distal-less homeobox 6	0.061
Tcirg1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3	0.061	Worm
Nrp1	neuropilin 1	0.060
Mfn2	mitofusin 2	0.060
Rxra	retinoid X receptor alpha	0.060
Cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	0.059
Ankrd1	ankyrin repeat domain 1 (cardiac muscle)	0.059	Rat
Runx1	runt related transcription factor 1	0.059
Plg	plasminogen	0.059	Mouse
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.058
Map3k6	mitogen-activated protein kinase kinase kinase 6	0.058
Zic3	zinc finger protein of the cerebellum 3	0.058
Prrx2	paired related homeobox 2	0.058
Cxcr4	chemokine (C-X-C motif) receptor 4	0.058	Human
Robo3	roundabout homolog 3 (Drosophila)	0.057
Dcc	deleted in colorectal carcinoma	0.057
Asgr2	asialoglycoprotein receptor 2	0.057
Aco2	aconitase 2, mitochondrial	0.057
Vav2	vav 2 oncogene	0.057
Nf2	neurofibromatosis 2	0.057
Pkd1	polycystic kidney disease 1 homolog	0.057
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.057
C1qtnf1	C1q and tumor necrosis factor related protein 1	0.056
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.056
Hic1	hypermethylated in cancer 1	0.056
Kcnh1	potassium voltage-gated channel, subfamily H (eag-related), member 1	0.056
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.056
Prlr	prolactin receptor	0.056
Cyp1b1	cytochrome P450, family 1, subfamily b, polypeptide 1	0.056
Slc6a18	solute carrier family 6 (neurotransmitter transporter), member 18	0.055
Cacna1s	calcium channel, voltage-dependent, L type, alpha 1S subunit	0.055
Ager	advanced glycosylation end product-specific receptor	0.055
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.055
Mitf	microphthalmia-associated transcription factor	0.055
Prkab1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.054
St6galnac3	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3	0.054
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.054
C3ar1	complement component 3a receptor 1	0.053
Prl	prolactin	0.053	Mouse
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.053
Itpr3	inositol 1,4,5-triphosphate receptor 3	0.053	Mouse
St8sia3	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3	0.052
Sh3pxd2b	SH3 and PX domains 2B	0.052
Cxcl12	chemokine (C-X-C motif) ligand 12	0.052
Ptrf	polymerase I and transcript release factor	0.052
Exoc6	exocyst complex component 6	0.052
Fzr1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.052
Abcc6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	0.052
Calca	calcitonin/calcitonin-related polypeptide, alpha	0.052
Mybph	myosin binding protein H	0.052
Kcnab3	potassium voltage-gated channel, shaker-related subfamily, beta member 3	0.051
Ptk2	PTK2 protein tyrosine kinase 2	0.051
Dmd	dystrophin, muscular dystrophy	0.051
Prkci	protein kinase C, iota	0.051
Rgs8	regulator of G-protein signaling 8	0.051
Des	desmin	0.051
Cacnb2	calcium channel, voltage-dependent, beta 2 subunit	0.050
Pdlim3	PDZ and LIM domain 3	0.050
Ntn1	netrin 1	0.050
Asxl1	additional sex combs like 1 (Drosophila)	0.050
Cxcl13	chemokine (C-X-C motif) ligand 13	0.050
Chrna7	cholinergic receptor, nicotinic, alpha polypeptide 7	0.050	Mouse
Socs1	suppressor of cytokine signaling 1	0.050
Vdr	vitamin D receptor	0.049	Mouse
Myh9	myosin, heavy polypeptide 9, non-muscle	0.049
Mgp	matrix Gla protein	0.049
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.049
Kcnd2	potassium voltage-gated channel, Shal-related family, member 2	0.049
Tcf3	transcription factor 3	0.049
Hmgb1	high mobility group box 1	0.049
Clcnka	chloride channel Ka	0.048
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.048
Arx	aristaless related homeobox	0.048
Fgf23	fibroblast growth factor 23	0.048
Kcns2	K+ voltage-gated channel, subfamily S, 2	0.048
Apoa1	apolipoprotein A-I	0.048
Sult5a1	sulfotransferase family 5A, member 1	0.047
Fli1	Friend leukemia integration 1	0.047
Mapkap1	mitogen-activated protein kinase associated protein 1	0.047
Chrng	cholinergic receptor, nicotinic, gamma polypeptide	0.047	Mouse
Hsf4	heat shock transcription factor 4	0.047
Hfe	hemochromatosis	0.047
Chrna9	cholinergic receptor, nicotinic, alpha polypeptide 9	0.047	Mouse
Ltb	lymphotoxin B	0.046
Tectb	tectorin beta	0.046
Aebp1	AE binding protein 1	0.046
Psen2	presenilin 2	0.046
Huwe1	HECT, UBA and WWE domain containing 1	0.046
Cdx2	caudal type homeobox 2	0.046
Mn1	meningioma 1	0.046
Fshr	follicle stimulating hormone receptor	0.046
Foxo3	forkhead box O3	0.045
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.045
Tgm2	transglutaminase 2, C polypeptide	0.045
Gpr50	G-protein-coupled receptor 50	0.045
Ppard	peroxisome proliferator activator receptor delta	0.045
Ebf3	early B-cell factor 3	0.045
Col13a1	collagen, type XIII, alpha 1	0.045
Mrpl4	mitochondrial ribosomal protein L4	0.045
Hnf4a	hepatic nuclear factor 4, alpha	0.045
Ikbkb	inhibitor of kappaB kinase beta	0.045
Mapk14	mitogen-activated protein kinase 14	0.044
Tnni2	troponin I, skeletal, fast 2	0.044
Fadd	Fas (TNFRSF6)-associated via death domain	0.044
Timp2	tissue inhibitor of metalloproteinase 2	0.044
Terf1	telomeric repeat binding factor 1	0.044
Casp1	caspase 1	0.044
Stc2	stanniocalcin 2	0.044
Wwtr1	WW domain containing transcription regulator 1	0.043
Ets1	E26 avian leukemia oncogene 1, 5' domain	0.043	Rat
Cd19	CD19 antigen	0.043
Mkl2	MKL/myocardin-like 2	0.043	Fly
Nmbr	neuromedin B receptor	0.043	Mouse
Tcfap2a	transcription factor AP-2, alpha	0.043
Pdk4	pyruvate dehydrogenase kinase, isoenzyme 4	0.043
Wnt10b	wingless related MMTV integration site 10b	0.043
Plcb1	phospholipase C, beta 1	0.043
Hand1	heart and neural crest derivatives expressed transcript 1	0.043	Mouse
Cldn2	claudin 2	0.043
Cryga	crystallin, gamma A	0.043
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.043
Grem1	gremlin 1	0.043
Tln1	talin 1	0.042
Bcl2l1	BCL2-like 1	0.042	Mouse
Itga5	integrin alpha 5 (fibronectin receptor alpha)	0.042
Junb	Jun-B oncogene	0.042
Rrm2b	ribonucleotide reductase M2 B (TP53 inducible)	0.042
Fgf7	fibroblast growth factor 7	0.042
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.042
Kcna1	potassium voltage-gated channel, shaker-related subfamily, member 1	0.042
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.042
Tyrp1	tyrosinase-related protein 1	0.042
Wwox	WW domain-containing oxidoreductase	0.041
Il4ra	interleukin 4 receptor, alpha	0.041
P2rx2	purinergic receptor P2X, ligand-gated ion channel, 2	0.041
Notch3	Notch gene homolog 3 (Drosophila)	0.041	Mouse
Lrfn1	leucine rich repeat and fibronectin type III domain containing 1	0.041
Scx	scleraxis	0.041	Mouse
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.041
Src	Rous sarcoma oncogene	0.041	Rat
Sct	secretin	0.041
Prf1	perforin 1 (pore forming protein)	0.041
Thbd	thrombomodulin	0.041
Dhh	desert hedgehog	0.041
Pycard	PYD and CARD domain containing	0.041
Igbp1b	immunoglobulin (CD79A) binding protein 1b	0.040
Pgk1	phosphoglycerate kinase 1	0.040
Fgf15	fibroblast growth factor 15	0.040
Edar	ectodysplasin-A receptor	0.040
Hspa9	heat shock protein 9	0.040
Ecm1	extracellular matrix protein 1	0.040
Rint1	RAD50 interactor 1	0.040
Flg	filaggrin	0.040
Adora3	adenosine A3 receptor	0.040
Gp5	glycoprotein 5 (platelet)	0.040
Hspd1	heat shock protein 1 (chaperonin)	0.040
Foxp3	forkhead box P3	0.040
Thrb	thyroid hormone receptor beta	0.039
Spry4	sprouty homolog 4 (Drosophila)	0.039
Gabrd	gamma-aminobutyric acid (GABA) A receptor, subunit delta	0.039
Foxi3	forkhead box I3	0.039
Alox12b	arachidonate 12-lipoxygenase, 12R type	0.039
Kcnq2	potassium voltage-gated channel, subfamily Q, member 2	0.039
Lct	lactase	0.039	Rat
Fgg	fibrinogen gamma chain	0.039
Stc1	stanniocalcin 1	0.039	Rat
Sec61a1	Sec61 alpha 1 subunit (S. cerevisiae)	0.039
Ptgir	prostaglandin I receptor (IP)	0.038
Fos	FBJ osteosarcoma oncogene	0.038
She	src homology 2 domain-containing transforming protein E	0.038
Kitl	kit ligand	0.038
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.038
Ptpn5	protein tyrosine phosphatase, non-receptor type 5	0.038
Slc6a2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.038
Ache	acetylcholinesterase	0.038
Cpxm2	carboxypeptidase X 2 (M14 family)	0.038
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.038
Hspa5	heat shock protein 5	0.038
Ahsg	alpha-2-HS-glycoprotein	0.038
Fam83f	family with sequence similarity 83, member F	0.038
Chrna10	cholinergic receptor, nicotinic, alpha polypeptide 10	0.038	Mouse
Icam1	intercellular adhesion molecule 1	0.038	Rat
Cdk6	cyclin-dependent kinase 6	0.037
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.037
Prkag1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	0.037
Ilk	integrin linked kinase	0.037
Cplx2	complexin 2	0.037
Rbpjl	recombination signal binding protein for immunoglobulin kappa J region-like	0.037
Tfrc	transferrin receptor	0.037
Il1b	interleukin 1 beta	0.037
Htr1d	5-hydroxytryptamine (serotonin) receptor 1D	0.037
Npc1	Niemann Pick type C1	0.037
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.037
Sox2	SRY-box containing gene 2	0.037
Hip1	huntingtin interacting protein 1	0.037
Rapsn	receptor-associated protein of the synapse	0.037
Fbxw7	F-box and WD-40 domain protein 7	0.037
Gabrq	gamma-aminobutyric acid (GABA) A receptor, subunit theta	0.037
Per1	period homolog 1 (Drosophila)	0.037
Mtor	mechanistic target of rapamycin (serine/threonine kinase)	0.037
Tspan12	tetraspanin 12	0.036
Proc	protein C	0.036
Scn9a	sodium channel, voltage-gated, type IX, alpha	0.036
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.036	Rat
Dpep1	dipeptidase 1 (renal)	0.036
Braf	Braf transforming gene	0.036
Sdc3	syndecan 3	0.036
Pgm2	phosphoglucomutase 2	0.036
Speg	SPEG complex locus	0.036
Cyp2d26	cytochrome P450, family 2, subfamily d, polypeptide 26	0.036
Plcg2	phospholipase C, gamma 2	0.036
Rln1	relaxin 1	0.036
Tdgf1	teratocarcinoma-derived growth factor 1	0.036
Slc17a6	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6	0.036
Npr3	natriuretic peptide receptor 3	0.036
Gbp5	guanylate binding protein 5	0.035
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.035
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.035
Per2	period homolog 2 (Drosophila)	0.035
Aff2	AF4/FMR2 family, member 2	0.035
Ryr1	ryanodine receptor 1, skeletal muscle	0.035	Human Mouse
Park2	Parkinson disease (autosomal recessive, juvenile) 2, parkin	0.035
Crb2	crumbs homolog 2 (Drosophila)	0.035
Krt14	keratin 14	0.035
Dnajb11	DnaJ (Hsp40) homolog, subfamily B, member 11	0.035
Nab2	Ngfi-A binding protein 2	0.035
Tm4sf1	transmembrane 4 superfamily member 1	0.035
Hes5	hairy and enhancer of split 5 (Drosophila)	0.035
Synpo	synaptopodin	0.035
Gpc3	glypican 3	0.035
Myom2	myomesin 2	0.034
Smn1	survival motor neuron 1	0.034
Gip	gastric inhibitory polypeptide	0.034
Zfp36	zinc finger protein 36	0.034
Ltbr	lymphotoxin B receptor	0.034
Spsb1	splA/ryanodine receptor domain and SOCS box containing 1	0.034
Clca3	chloride channel calcium activated 3	0.034
Scn1a	sodium channel, voltage-gated, type I, alpha	0.034
Sfn	stratifin	0.034
Adrb3	adrenergic receptor, beta 3	0.034
Mbl1	mannose-binding lectin (protein A) 1	0.034
Sdsl	serine dehydratase-like	0.034
Pnliprp2	pancreatic lipase-related protein 2	0.034
Lgr5	leucine rich repeat containing G protein coupled receptor 5	0.034
Pax3	paired box gene 3	0.034
Gaa	glucosidase, alpha, acid	0.034
Msx1	homeobox, msh-like 1	0.034
Eya4	eyes absent 4 homolog (Drosophila)	0.034
Calr	calreticulin	0.034
Plin4	perilipin 4	0.034
Mfng	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	0.034
Htr4	5 hydroxytryptamine (serotonin) receptor 4	0.034
Ehd2	EH-domain containing 2	0.034
Hgfac	hepatocyte growth factor activator	0.034	Mouse
Ndrg2	N-myc downstream regulated gene 2	0.034
Nr4a3	nuclear receptor subfamily 4, group A, member 3	0.033	Mouse
Msc	musculin	0.033
Snta1	syntrophin, acidic 1	0.033
Spesp1	sperm equatorial segment protein 1	0.033
Tek	endothelial-specific receptor tyrosine kinase	0.033
Rgs5	regulator of G-protein signaling 5	0.033
Cnn1	calponin 1	0.033
Kcnc3	potassium voltage gated channel, Shaw-related subfamily, member 3	0.033
Rs1	retinoschisis (X-linked, juvenile) 1 (human)	0.033
Adra1a	adrenergic receptor, alpha 1a	0.033
Abcb1a	ATP-binding cassette, sub-family B (MDR/TAP), member 1A	0.033
Ltk	leukocyte tyrosine kinase	0.033
Tyr	tyrosinase	0.033
Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.033	Human
Plat	plasminogen activator, tissue	0.033
Cdk4	cyclin-dependent kinase 4	0.033
Vip	vasoactive intestinal polypeptide	0.033
3110079O15Rik	RIKEN cDNA 3110079O15 gene	0.033
Pmp22	peripheral myelin protein 22	0.032
Bhlhe23	basic helix-loop-helix family, member e23	0.032
Jag1	jagged 1	0.032
Fam167b	family with sequence similarity 167, member B	0.032
Etv2	ets variant gene 2	0.032
Spna1	spectrin alpha 1	0.032
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.032
Nr4a2	nuclear receptor subfamily 4, group A, member 2	0.032
Sox18	SRY-box containing gene 18	0.032
Rasip1	Ras interacting protein 1	0.032
Lif	leukemia inhibitory factor	0.032
Sele	selectin, endothelial cell	0.032
Frmd8	FERM domain containing 8	0.032
Ptafr	platelet-activating factor receptor	0.032
Sox14	SRY-box containing gene 14	0.032
Fmo3	flavin containing monooxygenase 3	0.032
Dspp	dentin sialophosphoprotein	0.032
Uqcrfs1	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1	0.031
Gfpt2	glutamine fructose-6-phosphate transaminase 2	0.031
Mobp	myelin-associated oligodendrocytic basic protein	0.031
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.031
Il5	interleukin 5	0.031
Phb2	prohibitin 2	0.031
Htatip2	HIV-1 tat interactive protein 2, homolog (human)	0.031
Scn7a	sodium channel, voltage-gated, type VII, alpha	0.031
Fut4	fucosyltransferase 4	0.031
Thbs2	thrombospondin 2	0.031
Col4a2	collagen, type IV, alpha 2	0.031
ND6	NADH dehydrogenase subunit 6	0.031
Ctsk	cathepsin K	0.031
Cry2	cryptochrome 2 (photolyase-like)	0.031
Rbl2	retinoblastoma-like 2	0.031
Serpina1a	serine (or cysteine) peptidase inhibitor, clade A, member 1A	0.031	Rat
Acta1	actin, alpha 1, skeletal muscle	0.031
Lcn3	lipocalin 3	0.030
Spp2	secreted phosphoprotein 2	0.030
Hoxa1	homeobox A1	0.030
Prph2	peripherin 2	0.030
Eif4a2	eukaryotic translation initiation factor 4A2	0.030
Hnf1b	HNF1 homeobox B	0.030
Pax6	paired box gene 6	0.030
Ppp1r3c	protein phosphatase 1, regulatory (inhibitor) subunit 3C	0.030
Shbg	sex hormone binding globulin	0.030
Ptprn2	protein tyrosine phosphatase, receptor type, N polypeptide 2	0.030
Tlr2	toll-like receptor 2	0.030
Pvr	poliovirus receptor	0.030
Tnnc1	troponin C, cardiac/slow skeletal	0.030
Barx2	BarH-like homeobox 2	0.030
Golt1a	golgi transport 1 homolog A (S. cerevisiae)	0.030
Sox7	SRY-box containing gene 7	0.030
Emcn	endomucin	0.030
Plcd1	phospholipase C, delta 1	0.030
Cyld	cylindromatosis (turban tumor syndrome)	0.030
Wt1	Wilms tumor 1 homolog	0.030	Mouse
Pigr	polymeric immunoglobulin receptor	0.030
Mat1a	methionine adenosyltransferase I, alpha	0.030
Cacna1d	calcium channel, voltage-dependent, L type, alpha 1D subunit	0.029
Itga3	integrin alpha 3	0.029
Sgca	sarcoglycan, alpha (dystrophin-associated glycoprotein)	0.029
Pax9	paired box gene 9	0.029
Egln3	EGL nine homolog 3 (C. elegans)	0.029	Rat Worm Fly
Otud4	OTU domain containing 4	0.029
Foxf2	forkhead box F2	0.029
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.029
Adam23	a disintegrin and metallopeptidase domain 23	0.029
Slc1a2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.029
Pdgfb	platelet derived growth factor, B polypeptide	0.029
Cyp4a14	cytochrome P450, family 4, subfamily a, polypeptide 14	0.029
Pfkl	phosphofructokinase, liver, B-type	0.029
Smad2	MAD homolog 2 (Drosophila)	0.029
F2r	coagulation factor II (thrombin) receptor	0.029
Bag3	BCL2-associated athanogene 3	0.029
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.029
Chst14	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14	0.029
Hsd17b1	hydroxysteroid (17-beta) dehydrogenase 1	0.029
Angptl4	angiopoietin-like 4	0.029	Rat
Tead4	TEA domain family member 4	0.029
Hhex	hematopoietically expressed homeobox	0.029
Wnk2	WNK lysine deficient protein kinase 2	0.029
Gckr	glucokinase regulatory protein	0.029
Ccr1l1	chemokine (C-C motif) receptor 1-like 1	0.028
Ptpn21	protein tyrosine phosphatase, non-receptor type 21	0.028
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.028
Usp29	ubiquitin specific peptidase 29	0.028
Mark4	MAP/microtubule affinity-regulating kinase 4	0.028
Bnip3	BCL2/adenovirus E1B interacting protein 3	0.028	Human
Rictor	RPTOR independent companion of MTOR, complex 2	0.028
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.028
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.028
Tbr1	T-box brain gene 1	0.028
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.028
Ttn	titin	0.028
Lama4	laminin, alpha 4	0.028
Epha2	Eph receptor A2	0.028
Ghrl	ghrelin	0.028
Ptgfrn	prostaglandin F2 receptor negative regulator	0.028
Igfbp7	insulin-like growth factor binding protein 7	0.028
Flt4	FMS-like tyrosine kinase 4	0.028	Mouse
Mt3	metallothionein 3	0.028
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.028
Svep1	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1	0.028
Elk1	ELK1, member of ETS oncogene family	0.028
Mpz	myelin protein zero	0.028
Jak3	Janus kinase 3	0.028
Hck	hemopoietic cell kinase	0.027
Amdhd1	amidohydrolase domain containing 1	0.027
Prph	peripherin	0.027
Nptx1	neuronal pentraxin 1	0.027
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.027
Rdh7	retinol dehydrogenase 7	0.027
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.027
Nr2e1	nuclear receptor subfamily 2, group E, member 1	0.027
Myoz1	myozenin 1	0.027
Mybpc3	myosin binding protein C, cardiac	0.027
Sumo1	SMT3 suppressor of mif two 3 homolog 1 (yeast)	0.027
Bbc3	BCL2 binding component 3	0.027
Npr1	natriuretic peptide receptor 1	0.027
Blnk	B-cell linker	0.027
Atf2	activating transcription factor 2	0.027
Masp1	mannan-binding lectin serine peptidase 1	0.027
Chrnb1	cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)	0.027	Mouse
Bhlhe40	basic helix-loop-helix family, member e40	0.027
Vav3	vav 3 oncogene	0.027
Bhlha15	basic helix-loop-helix family, member a15	0.027	Mouse
Vldlr	very low density lipoprotein receptor	0.027	Rat
Hspb1	heat shock protein 1	0.027	Mouse Fly
Ereg	epiregulin	0.027
Alx4	aristaless-like homeobox 4	0.027
Kcnma1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	0.027
Cpe	carboxypeptidase E	0.027
Ccl7	chemokine (C-C motif) ligand 7	0.026
P2rx3	purinergic receptor P2X, ligand-gated ion channel, 3	0.026
Prkca	protein kinase C, alpha	0.026	Mouse
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.026
Kdelr3	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3	0.026
Capn3	calpain 3	0.026
Npn2	neoplastic progression 2	0.026
Galr1	galanin receptor 1	0.026
Chrna5	cholinergic receptor, nicotinic, alpha polypeptide 5	0.026	Mouse
Allc	allantoicase	0.026
Gsx1	GS homeobox 1	0.026
Col4a1	collagen, type IV, alpha 1	0.026
Cyp24a1	cytochrome P450, family 24, subfamily a, polypeptide 1	0.026
Pdgfa	platelet derived growth factor, alpha	0.026
Adora2b	adenosine A2b receptor	0.026
D4Wsu53e	DNA segment, Chr 4, Wayne State University 53, expressed	0.026
Bid	BH3 interacting domain death agonist	0.026
Nkx3-2	NK3 homeobox 2	0.026
Msln	mesothelin	0.026
Saa4	serum amyloid A 4	0.026
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.026
Itgbl1	integrin, beta-like 1	0.026
Atp5g3	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)	0.026
Nr5a2	nuclear receptor subfamily 5, group A, member 2	0.026
Echs1	enoyl Coenzyme A hydratase, short chain, 1, mitochondrial	0.026
Dmbx1	diencephalon/mesencephalon homeobox 1	0.026
Msh2	mutS homolog 2 (E. coli)	0.026
Ppfia4	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4	0.026
Bcan	brevican	0.026
Dtna	dystrobrevin alpha	0.026
Amotl2	angiomotin-like 2	0.026
Fam20c	family with sequence similarity 20, member C	0.026
Tll1	tolloid-like	0.025
Ccnb2	cyclin B2	0.025
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.025
Mrgprf	MAS-related GPR, member F	0.025
Hdac7	histone deacetylase 7	0.025
Hmgcs2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2	0.025
Sik3	SIK family kinase 3	0.025
March6	membrane-associated ring finger (C3HC4) 6	0.025
Stk4	serine/threonine kinase 4	0.025
Sstr2	somatostatin receptor 2	0.025
Hand2	heart and neural crest derivatives expressed transcript 2	0.025	Mouse
Wnt3a	wingless-related MMTV integration site 3A	0.025
Slc34a2	solute carrier family 34 (sodium phosphate), member 2	0.025
Crb1	crumbs homolog 1 (Drosophila)	0.025
Sftpd	surfactant associated protein D	0.025
Lbp	lipopolysaccharide binding protein	0.025
Slc44a2	solute carrier family 44, member 2	0.025
Gjb5	gap junction protein, beta 5	0.025
Adra2c	adrenergic receptor, alpha 2c	0.025
Chia	chitinase, acidic	0.025
Fndc7	fibronectin type III domain containing 7	0.025
Elovl3	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3	0.025
Ctrb1	chymotrypsinogen B1	0.025
Gpi1	glucose phosphate isomerase 1	0.025
Hbb-b2	hemoglobin, beta adult minor chain	0.025
S100b	S100 protein, beta polypeptide, neural	0.025	Rat
Mvp	major vault protein	0.024
Pdc	phosducin	0.024
Grik1	glutamate receptor, ionotropic, kainate 1	0.024
Map1lc3b	microtubule-associated protein 1 light chain 3 beta	0.024
Csk	c-src tyrosine kinase	0.024
Tor3a	torsin family 3, member A	0.024
Timp4	tissue inhibitor of metalloproteinase 4	0.024
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.024
Bmp8b	bone morphogenetic protein 8b	0.024
Smad5	MAD homolog 5 (Drosophila)	0.024
Hc	hemolytic complement	0.024
Cd47	CD47 antigen (Rh-related antigen, integrin-associated signal transducer)	0.024
Nppa	natriuretic peptide type A	0.024	Rat
Gem	GTP binding protein (gene overexpressed in skeletal muscle)	0.024
Hdac2	histone deacetylase 2	0.024
Esr2	estrogen receptor 2 (beta)	0.024
Itpr2	inositol 1,4,5-triphosphate receptor 2	0.024	Human Mouse
Casp3	caspase 3	0.024	Mouse
Pla2r1	phospholipase A2 receptor 1	0.024
Rasd1	RAS, dexamethasone-induced 1	0.024
Bmx	BMX non-receptor tyrosine kinase	0.024
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.024
Neurod6	neurogenic differentiation 6	0.024	Mouse
Pip4k2a	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	0.024
Tmem204	transmembrane protein 204	0.024
P2ry2	purinergic receptor P2Y, G-protein coupled 2	0.024
Serpine2	serine (or cysteine) peptidase inhibitor, clade E, member 2	0.024
Myog	myogenin	0.024
Otc	ornithine transcarbamylase	0.024
Pgf	placental growth factor	0.024
Fgfr4	fibroblast growth factor receptor 4	0.024
Plvap	plasmalemma vesicle associated protein	0.024
Irs1	insulin receptor substrate 1	0.024
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.024
Btg2	B-cell translocation gene 2, anti-proliferative	0.024
Bub1	budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)	0.024
Apobec1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	0.024
Kiss1r	KISS1 receptor	0.024
Mr1	major histocompatibility complex, class I-related	0.023
Xirp1	xin actin-binding repeat containing 1	0.023
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.023	Rat
Smarcd1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.023