IMP: Integrative Multi-species Prediction

Mus musculus

81 genes annotated in mouse

negative regulation of kinase activity

Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of kinase activity"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "negative regulation of kinase activity" (in gray)

Name	Description	Probability	Func Analog Organism
Apc	adenomatosis polyposis coli	0.999	Human
Ctnnb1	catenin (cadherin associated protein), beta 1	0.998
Trp53	transformation related protein 53	0.988	Mouse Fly
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.985
Cbl	Casitas B-lineage lymphoma	0.984	Fly
Pten	phosphatase and tensin homolog	0.984	Human
Fyn	Fyn proto-oncogene	0.966	Mouse
Dok1	docking protein 1	0.964
Grb2	growth factor receptor bound protein 2	0.945	Fly
Bmp4	bone morphogenetic protein 4	0.932	Human
Mdm2	transformed mouse 3T3 cell double minute 2	0.920
Ghr	growth hormone receptor	0.920
Gsk3b	glycogen synthase kinase 3 beta	0.910	Rat Fly
Nf2	neurofibromatosis 2	0.903
Psen1	presenilin 1	0.887
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.881	Mouse
Fgfr1	fibroblast growth factor receptor 1	0.865
Traf6	TNF receptor-associated factor 6	0.864
Foxa2	forkhead box A2	0.841
Clock	circadian locomotor output cycles kaput	0.833
Arrb2	arrestin, beta 2	0.833	Fly
Axin1	axin 1	0.817
Fgfr3	fibroblast growth factor receptor 3	0.794
Plcg2	phospholipase C, gamma 2	0.793
Irs2	insulin receptor substrate 2	0.791
Insr	insulin receptor	0.786
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.744
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.728
Foxc1	forkhead box C1	0.719	Mouse
Fos	FBJ osteosarcoma oncogene	0.706
Notch1	Notch gene homolog 1 (Drosophila)	0.685
Blnk	B-cell linker	0.674
Cd151	CD151 antigen	0.669
Prkce	protein kinase C, epsilon	0.659	Mouse
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.630
Rb1	retinoblastoma 1	0.624	Human
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.614
Msx1	homeobox, msh-like 1	0.610
Ptch1	patched homolog 1	0.608
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.583
Ptk2	PTK2 protein tyrosine kinase 2	0.575	Fly
Lepr	leptin receptor	0.566
Gli3	GLI-Kruppel family member GLI3	0.542
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.542
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.536
Zeb1	zinc finger E-box binding homeobox 1	0.534
Pparg	peroxisome proliferator activated receptor gamma	0.530
Ncoa3	nuclear receptor coactivator 3	0.514
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.513
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.507
Src	Rous sarcoma oncogene	0.506	Mouse
Gbp5	guanylate binding protein 5	0.504
Shh	sonic hedgehog	0.501
Vegfa	vascular endothelial growth factor A	0.487
Tnf	tumor necrosis factor	0.483
Prrx1	paired related homeobox 1	0.483
Inpp5d	inositol polyphosphate-5-phosphatase D	0.464
Egfr	epidermal growth factor receptor	0.463
Irs1	insulin receptor substrate 1	0.450	Mouse
Ccnd1	cyclin D1	0.429
Fgfr2	fibroblast growth factor receptor 2	0.428
Zfp36	zinc finger protein 36	0.409
Enah	enabled homolog (Drosophila)	0.404	Mouse
Yap1	yes-associated protein 1	0.404
Dok2	docking protein 2	0.403
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.397
Tsc1	tuberous sclerosis 1	0.392
Aim2	absent in melanoma 2	0.383
Hsp90aa1	heat shock protein 90, alpha (cytosolic), class A member 1	0.360
Mdm4	transformed mouse 3T3 cell double minute 4	0.356
Bcl2	B-cell leukemia/lymphoma 2	0.346
Spry1	sprouty homolog 1 (Drosophila)	0.344
Smurf2	SMAD specific E3 ubiquitin protein ligase 2	0.338
Prkcb	protein kinase C, beta	0.337	Mouse
Pbx1	pre B-cell leukemia transcription factor 1	0.335
Spry2	sprouty homolog 2 (Drosophila)	0.329
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.324
Mapk14	mitogen-activated protein kinase 14	0.312
Rxra	retinoid X receptor alpha	0.312
Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.309	Human
Ly86	lymphocyte antigen 86	0.308
Cd40	CD40 antigen	0.306
Ikzf1	IKAROS family zinc finger 1	0.305
Arl4c	ADP-ribosylation factor-like 4C	0.304
Cdh5	cadherin 5	0.304
Vasp	vasodilator-stimulated phosphoprotein	0.303	Mouse
Skil	SKI-like	0.303
Notch2	Notch gene homolog 2 (Drosophila)	0.297
Ptk2b	PTK2 protein tyrosine kinase 2 beta	0.292	Fly
Runx2	runt related transcription factor 2	0.281
Evl	Ena-vasodilator stimulated phosphoprotein	0.281	Mouse
Stat3	signal transducer and activator of transcription 3	0.280
Smo	smoothened homolog (Drosophila)	0.279
Myd88	myeloid differentiation primary response gene 88	0.270
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.266	Human
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.257
Esr1	estrogen receptor 1 (alpha)	0.255
Igf2	insulin-like growth factor 2	0.251
Trp73	transformation related protein 73	0.249
Ldb3	LIM domain binding 3	0.249
Atf4	activating transcription factor 4	0.247
Il1b	interleukin 1 beta	0.247
Nck2	non-catalytic region of tyrosine kinase adaptor protein 2	0.243
Lep	leptin	0.241
Efnb2	ephrin B2	0.238
Cdk4	cyclin-dependent kinase 4	0.226
Map4k1	mitogen-activated protein kinase kinase kinase kinase 1	0.226
Prkaca	protein kinase, cAMP dependent, catalytic, alpha	0.225
Sox17	SRY-box containing gene 17	0.221
E2f1	E2F transcription factor 1	0.221
Thrb	thyroid hormone receptor beta	0.216
Fas	Fas (TNF receptor superfamily member 6)	0.215
Klf7	Kruppel-like factor 7 (ubiquitous)	0.214
Irak4	interleukin-1 receptor-associated kinase 4	0.214
Dnajb4	DnaJ (Hsp40) homolog, subfamily B, member 4	0.212
Nf1	neurofibromatosis 1	0.212
Cotl1	coactosin-like 1 (Dictyostelium)	0.212
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.210
Krt14	keratin 14	0.208
Pxn	paxillin	0.208
Trim28	tripartite motif-containing 28	0.208
Gli2	GLI-Kruppel family member GLI2	0.207
Csk	c-src tyrosine kinase	0.206	Rat
Pip4k2a	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	0.201
Runx1	runt related transcription factor 1	0.201
Vcl	vinculin	0.197
Grm1	glutamate receptor, metabotropic 1	0.197
Bcar1	breast cancer anti-estrogen resistance 1	0.197
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.197
Whrn	whirlin	0.196
Hes1	hairy and enhancer of split 1 (Drosophila)	0.195
Emx1	empty spiracles homolog 1 (Drosophila)	0.193
Nab2	Ngfi-A binding protein 2	0.192
Jak1	Janus kinase 1	0.190
Cav1	caveolin 1, caveolae protein	0.186
Pvrl2	poliovirus receptor-related 2	0.185
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.182
Bmp7	bone morphogenetic protein 7	0.182	Human
Cd86	CD86 antigen	0.182
Cdkn2d	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	0.177	Human
Efnb1	ephrin B1	0.175
Zbtb7b	zinc finger and BTB domain containing 7B	0.174
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.172
Kiss1	KiSS-1 metastasis-suppressor	0.171
Nsf	N-ethylmaleimide sensitive fusion protein	0.170
En1	engrailed 1	0.170
Wnt6	wingless-related MMTV integration site 6	0.169
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.168
Sfrp1	secreted frizzled-related protein 1	0.167
Prkcd	protein kinase C, delta	0.167	Human
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.165
Mapk9	mitogen-activated protein kinase 9	0.164	Fly
Braf	Braf transforming gene	0.158
Pias2	protein inhibitor of activated STAT 2	0.157
Nlrp3	NLR family, pyrin domain containing 3	0.155
Stk4	serine/threonine kinase 4	0.154
Drd2	dopamine receptor D2	0.153
Sav1	salvador homolog 1 (Drosophila)	0.150
Dvl2	dishevelled 2, dsh homolog (Drosophila)	0.150
Chrd	chordin	0.148
Drd4	dopamine receptor D4	0.146
Tgfb2	transforming growth factor, beta 2	0.145
Ahr	aryl-hydrocarbon receptor	0.145
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.145
Socs1	suppressor of cytokine signaling 1	0.144
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.144
Foxo1	forkhead box O1	0.142
Il1r1	interleukin 1 receptor, type I	0.141
Irf8	interferon regulatory factor 8	0.140
Sfrp2	secreted frizzled-related protein 2	0.139
Hand1	heart and neural crest derivatives expressed transcript 1	0.139
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.139
Jun	Jun oncogene	0.138
Sykb	spleen tyrosine kinase	0.137
Gpc3	glypican 3	0.136
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.136
Lrp6	low density lipoprotein receptor-related protein 6	0.134	Human
Cdc42ep1	CDC42 effector protein (Rho GTPase binding) 1	0.134
Plcd1	phospholipase C, delta 1	0.132
Thbs1	thrombospondin 1	0.130
Shc1	src homology 2 domain-containing transforming protein C1	0.130
Ptpre	protein tyrosine phosphatase, receptor type, E	0.129	Mouse
Amotl2	angiomotin-like 2	0.128
Rgs5	regulator of G-protein signaling 5	0.128	Mouse
Mapk8	mitogen-activated protein kinase 8	0.127	Fly
Ret	ret proto-oncogene	0.126
Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3	0.126
Ednrb	endothelin receptor type B	0.126
Amhr2	anti-Mullerian hormone type 2 receptor	0.123
Rora	RAR-related orphan receptor alpha	0.122
Ezh1	enhancer of zeste homolog 1 (Drosophila)	0.122
Fosl2	fos-like antigen 2	0.121
Gas1	growth arrest specific 1	0.120
Lhx3	LIM homeobox protein 3	0.119
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.118
Il18	interleukin 18	0.118
Eif2c2	eukaryotic translation initiation factor 2C, 2	0.117
Fam65b	family with sequence similarity 65, member B	0.116
Arrb1	arrestin, beta 1	0.115	Fly
Daxx	Fas death domain-associated protein	0.115
Siah2	seven in absentia 2	0.115
Sh3kbp1	SH3-domain kinase binding protein 1	0.114
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.114
Vgf	VGF nerve growth factor inducible	0.114
Twist1	twist homolog 1 (Drosophila)	0.113
Kit	kit oncogene	0.113
Dscaml1	Down syndrome cell adhesion molecule-like 1	0.113
Coro1a	coronin, actin binding protein 1A	0.112
Gdf15	growth differentiation factor 15	0.111
Ctnnd1	catenin (cadherin associated protein), delta 1	0.111
Cldn5	claudin 5	0.111
Nfatc1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.110
Cyr61	cysteine rich protein 61	0.108
Nradd	neurotrophin receptor associated death domain	0.107
Fcgr1	Fc receptor, IgG, high affinity I	0.107
Rel	reticuloendotheliosis oncogene	0.105
Kitl	kit ligand	0.105
Ddx6	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6	0.103
Cd36	CD36 antigen	0.103
Klc1	kinesin light chain 1	0.103
C1qb	complement component 1, q subcomponent, beta polypeptide	0.103	Mouse
Pgr	progesterone receptor	0.103
Kdr	kinase insert domain protein receptor	0.102
Was	Wiskott-Aldrich syndrome homolog (human)	0.102
Dbnl	drebrin-like	0.101
Aif1	allograft inflammatory factor 1	0.100
Gna11	guanine nucleotide binding protein, alpha 11	0.100
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.098
Mapk1	mitogen-activated protein kinase 1	0.098
Vhl	von Hippel-Lindau tumor suppressor	0.098
Spry4	sprouty homolog 4 (Drosophila)	0.098
Lef1	lymphoid enhancer binding factor 1	0.096
Dlx5	distal-less homeobox 5	0.096
Cd22	CD22 antigen	0.096
Stk11	serine/threonine kinase 11	0.096
Prkci	protein kinase C, iota	0.095
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.094
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.093
Grb10	growth factor receptor bound protein 10	0.091
Flt1	FMS-like tyrosine kinase 1	0.091
Ptgir	prostaglandin I receptor (IP)	0.091
Fyb	FYN binding protein	0.090
Sox7	SRY-box containing gene 7	0.090
Dlx2	distal-less homeobox 2	0.090
Ptprc	protein tyrosine phosphatase, receptor type, C	0.089
Rax	retina and anterior neural fold homeobox	0.088
Dsg1a	desmoglein 1 alpha	0.087
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.086	Human
Bnc1	basonuclin 1	0.086
Akt1	thymoma viral proto-oncogene 1	0.086	Human Rat
Wwox	WW domain-containing oxidoreductase	0.085
Grk6	G protein-coupled receptor kinase 6	0.085
Ptprn	protein tyrosine phosphatase, receptor type, N	0.085
Emcn	endomucin	0.085
Fbxw7	F-box and WD-40 domain protein 7	0.085
Tek	endothelial-specific receptor tyrosine kinase	0.084
Fermt2	fermitin family homolog 2 (Drosophila)	0.084
Pnpla2	patatin-like phospholipase domain containing 2	0.084
Nos3	nitric oxide synthase 3, endothelial cell	0.083
Ets1	E26 avian leukemia oncogene 1, 5' domain	0.083
Bmp2	bone morphogenetic protein 2	0.083
Aph1a	anterior pharynx defective 1a homolog (C. elegans)	0.082
Egr1	early growth response 1	0.082	Worm
Bdnf	brain derived neurotrophic factor	0.081
Npr3	natriuretic peptide receptor 3	0.080
Cul9	cullin 9	0.080
Itsn1	intersectin 1 (SH3 domain protein 1A)	0.080
Nbn	nibrin	0.080
Samd4	sterile alpha motif domain containing 4	0.079
Mtf2	metal response element binding transcription factor 2	0.079
Hcls1	hematopoietic cell specific Lyn substrate 1	0.078
Hand2	heart and neural crest derivatives expressed transcript 2	0.078
Slc26a4	solute carrier family 26, member 4	0.078
Cdc42se1	CDC42 small effector 1	0.077
Il1a	interleukin 1 alpha	0.077	Mouse
Dlg1	discs, large homolog 1 (Drosophila)	0.077
Wdr1	WD repeat domain 1	0.076
Sema4d	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	0.076
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.076
Ppp1r9b	protein phosphatase 1, regulatory subunit 9B	0.075
Pou2f2	POU domain, class 2, transcription factor 2	0.075
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.075
Brca1	breast cancer 1	0.075
Hmx1	H6 homeobox 1	0.075
Ephb2	Eph receptor B2	0.075
Smad7	MAD homolog 7 (Drosophila)	0.074
Gsta4	glutathione S-transferase, alpha 4	0.074	Mouse
Foxm1	forkhead box M1	0.073
Arc	activity regulated cytoskeletal-associated protein	0.073
Msx2	homeobox, msh-like 2	0.073
Rasa1	RAS p21 protein activator 1	0.072
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.072
Rbm42	RNA binding motif protein 42	0.072
Psap	prosaposin	0.072
Ece1	endothelin converting enzyme 1	0.071
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.071
Cd38	CD38 antigen	0.071
Chd7	chromodomain helicase DNA binding protein 7	0.071
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.071
Junb	Jun-B oncogene	0.071
Dll1	delta-like 1 (Drosophila)	0.071
Rock2	Rho-associated coiled-coil containing protein kinase 2	0.071
Mdfi	MyoD family inhibitor	0.071
Sh2b2	SH2B adaptor protein 2	0.070
Btk	Bruton agammaglobulinemia tyrosine kinase	0.070	Mouse
Mn1	meningioma 1	0.070
Smad6	MAD homolog 6 (Drosophila)	0.069
Tspan7	tetraspanin 7	0.069
Phlda1	pleckstrin homology-like domain, family A, member 1	0.069
Prkcc	protein kinase C, gamma	0.068
Sertad2	SERTA domain containing 2	0.068
Fbxo30	F-box protein 30	0.068
Epas1	endothelial PAS domain protein 1	0.068
Otx2	orthodenticle homolog 2 (Drosophila)	0.068
Id1	inhibitor of DNA binding 1	0.068
Skap2	src family associated phosphoprotein 2	0.068
Kcnab2	potassium voltage-gated channel, shaker-related subfamily, beta member 2	0.067
Epha2	Eph receptor A2	0.067
Rtn2	reticulon 2 (Z-band associated protein)	0.067
Casp7	caspase 7	0.067	Mouse
Cd72	CD72 antigen	0.067
Gadd45g	growth arrest and DNA-damage-inducible 45 gamma	0.066
Sorbs1	sorbin and SH3 domain containing 1	0.066
Spib	Spi-B transcription factor (Spi-1/PU.1 related)	0.066
Men1	multiple endocrine neoplasia 1	0.065	Human
Ctnna1	catenin (cadherin associated protein), alpha 1	0.065
Ptgs2	prostaglandin-endoperoxide synthase 2	0.065
Pik3ap1	phosphoinositide-3-kinase adaptor protein 1	0.064
Crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.064
Rbl1	retinoblastoma-like 1 (p107)	0.064
Hipk3	homeodomain interacting protein kinase 3	0.064
Adrb1	adrenergic receptor, beta 1	0.064
Pag1	phosphoprotein associated with glycosphingolipid microdomains 1	0.063
Smap2	stromal membrane-associated GTPase-activating protein 2	0.063
Cd83	CD83 antigen	0.063
Asap1	ArfGAP with SH# domain, ankyrin repeat and PH domain1	0.063
Kcnj8	potassium inwardly-rectifying channel, subfamily J, member 8	0.063
Eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2	0.063
Ifrd1	interferon-related developmental regulator 1	0.063
Socs5	suppressor of cytokine signaling 5	0.063	Human
Wnt3a	wingless-related MMTV integration site 3A	0.063
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.062
Pdlim4	PDZ and LIM domain 4	0.062
Wnt4	wingless-related MMTV integration site 4	0.062
Akap9	A kinase (PRKA) anchor protein (yotiao) 9	0.062
Sh3bp2	SH3-domain binding protein 2	0.061
Lasp1	LIM and SH3 protein 1	0.061
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.061
Meox2	mesenchyme homeobox 2	0.061
Gdnf	glial cell line derived neurotrophic factor	0.061
Wwtr1	WW domain containing transcription regulator 1	0.061	Human
Rap2a	RAS related protein 2a	0.061
Nog	noggin	0.061
Dok3	docking protein 3	0.060
Hsph1	heat shock 105kDa/110kDa protein 1	0.060
Slc32a1	solute carrier family 32 (GABA vesicular transporter), member 1	0.060
Pax3	paired box gene 3	0.060
Crb2	crumbs homolog 2 (Drosophila)	0.060
Kif1c	kinesin family member 1C	0.059
Ubc	ubiquitin C	0.059
Il2rg	interleukin 2 receptor, gamma chain	0.058
Ier5	immediate early response 5	0.058
Phf17	PHD finger protein 17	0.058
Fscn1	fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)	0.058
Fadd	Fas (TNFRSF6)-associated via death domain	0.058
Ptprq	protein tyrosine phosphatase, receptor type, Q	0.058	Mouse
Chuk	conserved helix-loop-helix ubiquitous kinase	0.058
Spnb2	spectrin beta 2	0.058
Fermt3	fermitin family homolog 3 (Drosophila)	0.057
Rasa3	RAS p21 protein activator 3	0.057
Marcksl1	MARCKS-like 1	0.057
Pgam2	phosphoglycerate mutase 2	0.056
Nkx2-1	NK2 homeobox 1	0.056
Aff1	AF4/FMR2 family, member 1	0.056
Crabp2	cellular retinoic acid binding protein II	0.056	Mouse
Ier5l	immediate early response 5-like	0.056
Fgf21	fibroblast growth factor 21	0.056
Prrx2	paired related homeobox 2	0.056
Sox18	SRY-box containing gene 18	0.055
Kiss1r	KISS1 receptor	0.055
Cd4	CD4 antigen	0.055
Mapkapk2	MAP kinase-activated protein kinase 2	0.055
Carm1	coactivator-associated arginine methyltransferase 1	0.055
Crlf3	cytokine receptor-like factor 3	0.055
Rarb	retinoic acid receptor, beta	0.055
Mcoln2	mucolipin 2	0.054
Xpa	xeroderma pigmentosum, complementation group A	0.054
Ephb3	Eph receptor B3	0.054
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.054
Myc	myelocytomatosis oncogene	0.054
Mdk	midkine	0.054
Vsx2	visual system homeobox 2	0.054
Usp22	ubiquitin specific peptidase 22	0.053
Ptpn21	protein tyrosine phosphatase, non-receptor type 21	0.053
Diap1	diaphanous homolog 1 (Drosophila)	0.053
Crb3	crumbs homolog 3 (Drosophila)	0.053
Pax9	paired box gene 9	0.053
Gipc3	GIPC PDZ domain containing family, member 3	0.053
Ripk3	receptor-interacting serine-threonine kinase 3	0.052
Crybb2	crystallin, beta B2	0.052
Lcp1	lymphocyte cytosolic protein 1	0.052
Hipk1	homeodomain interacting protein kinase 1	0.052	Mouse
Slc5a5	solute carrier family 5 (sodium iodide symporter), member 5	0.052
Bid	BH3 interacting domain death agonist	0.052
Irf5	interferon regulatory factor 5	0.052
Rhbdf1	rhomboid family 1 (Drosophila)	0.052
Shc3	src homology 2 domain-containing transforming protein C3	0.051
Arhgap1	Rho GTPase activating protein 1	0.051
Ptprn2	protein tyrosine phosphatase, receptor type, N polypeptide 2	0.051
Lipe	lipase, hormone sensitive	0.051
Csnk1e	casein kinase 1, epsilon	0.051
Gck	glucokinase	0.050
Tead2	TEA domain family member 2	0.050
Ncf1	neutrophil cytosolic factor 1	0.050
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.050
Asprv1	aspartic peptidase, retroviral-like 1	0.050
Tnip1	TNFAIP3 interacting protein 1	0.050
Tead1	TEA domain family member 1	0.050
Rac1	RAS-related C3 botulinum substrate 1	0.050
Calb2	calbindin 2	0.049
Rara	retinoic acid receptor, alpha	0.049
Tnnc1	troponin C, cardiac/slow skeletal	0.049
Ptov1	prostate tumor over expressed gene 1	0.049
Igh	immunoglobulin heavy chain complex	0.049
Actn1	actinin, alpha 1	0.049
Rab10	RAB10, member RAS oncogene family	0.049
Mark2	MAP/microtubule affinity-regulating kinase 2	0.049
Tsc2	tuberous sclerosis 2	0.049
Csf1	colony stimulating factor 1 (macrophage)	0.049
Apbb1	amyloid beta (A4) precursor protein-binding, family B, member 1	0.049
Iqcj-schip1	IQ motif containing J-schwannomin interacting protein 1 readthrough	0.048
Dnajc5	DnaJ (Hsp40) homolog, subfamily C, member 5	0.048
Ceacam16	carcinoembryonic antigen-related cell adhesion molecule 16	0.048
Ppp1r15a	protein phosphatase 1, regulatory (inhibitor) subunit 15A	0.048
Klf2	Kruppel-like factor 2 (lung)	0.048
Sf3a2	splicing factor 3a, subunit 2	0.048
Scg3	secretogranin III	0.048
Atxn7l3	ataxin 7-like 3	0.048
Msh2	mutS homolog 2 (E. coli)	0.048
Olfm1	olfactomedin 1	0.048
Ski	ski sarcoma viral oncogene homolog (avian)	0.047
Cdh23	cadherin 23 (otocadherin)	0.047
Cd80	CD80 antigen	0.047
Btg2	B-cell translocation gene 2, anti-proliferative	0.047
Tgif1	TGFB-induced factor homeobox 1	0.047
Acvr1	activin A receptor, type 1	0.047
Fhl1	four and a half LIM domains 1	0.047
Jak2	Janus kinase 2	0.047
Fam3b	family with sequence similarity 3, member B	0.047
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.047
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.047
Arhgef7	Rho guanine nucleotide exchange factor (GEF7)	0.047
Ddah2	dimethylarginine dimethylaminohydrolase 2	0.047
Klk8	kallikrein related-peptidase 8	0.047
Hivep2	human immunodeficiency virus type I enhancer binding protein 2	0.047
Cdh13	cadherin 13	0.047
Cdh1	cadherin 1	0.047
Sox9	SRY-box containing gene 9	0.047
Srf	serum response factor	0.046
Pitx3	paired-like homeodomain transcription factor 3	0.046
Bag3	BCL2-associated athanogene 3	0.046
Rasgrp1	RAS guanyl releasing protein 1	0.046
Scg2	secretogranin II	0.046
Kif1b	kinesin family member 1B	0.046
Hspa1b	heat shock protein 1B	0.046
Tnfrsf12a	tumor necrosis factor receptor superfamily, member 12a	0.046
Slc6a12	solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12	0.046
Iffo2	intermediate filament family orphan 2	0.046
Ephb4	Eph receptor B4	0.045
Jub	ajuba	0.045
Hoxd13	homeobox D13	0.045
Homer1	homer homolog 1 (Drosophila)	0.045
Ier2	immediate early response 2	0.045
Socs2	suppressor of cytokine signaling 2	0.045
Numb	numb gene homolog (Drosophila)	0.045
Alx1	ALX homeobox 1	0.044
Akap3	A kinase (PRKA) anchor protein 3	0.044
Onecut3	one cut domain, family member 3	0.044
1500003O03Rik	RIKEN cDNA 1500003O03 gene	0.044	Rat
Lrrc8c	leucine rich repeat containing 8 family, member C	0.044
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.044
Pvrl3	poliovirus receptor-related 3	0.044
Hoxa1	homeobox A1	0.044
Sirpa	signal-regulatory protein alpha	0.044
Lif	leukemia inhibitory factor	0.044
Pde4b	phosphodiesterase 4B, cAMP specific	0.044
Hbegf	heparin-binding EGF-like growth factor	0.044
Chrdl2	chordin-like 2	0.044
Ar	androgen receptor	0.044
Bhlhe40	basic helix-loop-helix family, member e40	0.044
Tbx3	T-box 3	0.043
Cish	cytokine inducible SH2-containing protein	0.043
Tspan9	tetraspanin 9	0.043
Pppde2	PPPDE peptidase domain containing 2	0.043
Ppard	peroxisome proliferator activator receptor delta	0.043
Ptk7	PTK7 protein tyrosine kinase 7	0.043
Tle1	transducin-like enhancer of split 1, homolog of Drosophila E(spl)	0.043
Apbb1ip	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	0.043
Akap2	A kinase (PRKA) anchor protein 2	0.043
Peli2	pellino 2	0.043
Gimap1	GTPase, IMAP family member 1	0.043
Sult4a1	sulfotransferase family 4A, member 1	0.043
S1pr3	sphingosine-1-phosphate receptor 3	0.043
Arhgap5	Rho GTPase activating protein 5	0.043
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.043
Dusp1	dual specificity phosphatase 1	0.043	Human Mouse
Kcna6	potassium voltage-gated channel, shaker-related, subfamily, member 6	0.042
Cdk9	cyclin-dependent kinase 9 (CDC2-related kinase)	0.042
Ush1c	Usher syndrome 1C homolog (human)	0.042
Il17ra	interleukin 17 receptor A	0.042
Gsc	goosecoid homeobox	0.042
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.042
Fshr	follicle stimulating hormone receptor	0.042
Suz12	suppressor of zeste 12 homolog (Drosophila)	0.042
App	amyloid beta (A4) precursor protein	0.042
Cxcl2	chemokine (C-X-C motif) ligand 2	0.042
Gucy2e	guanylate cyclase 2e	0.042
Vstm2b	V-set and transmembrane domain containing 2B	0.042
Scrt1	scratch homolog 1, zinc finger protein (Drosophila)	0.042
Adrbk1	adrenergic receptor kinase, beta 1	0.041
Sh3bp4	SH3-domain binding protein 4	0.041
Twist2	twist homolog 2 (Drosophila)	0.041
Chl1	cell adhesion molecule with homology to L1CAM	0.041
Gata6	GATA binding protein 6	0.041
Myh10	myosin, heavy polypeptide 10, non-muscle	0.041
Cap1	CAP, adenylate cyclase-associated protein 1 (yeast)	0.041
Vax2	ventral anterior homeobox containing gene 2	0.041
Epx	eosinophil peroxidase	0.041
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.041
Jarid2	jumonji, AT rich interactive domain 2	0.041
Foxo3	forkhead box O3	0.041
Mkl1	MKL (megakaryoblastic leukemia)/myocardin-like 1	0.041
Zbtb46	zinc finger and BTB domain containing 46	0.041
Hoxc9	homeobox C9	0.041
Hif1a	hypoxia inducible factor 1, alpha subunit	0.041
Emp2	epithelial membrane protein 2	0.041
Nlrp6	NLR family, pyrin domain containing 6	0.040
Areg	amphiregulin	0.040
Znrf1	zinc and ring finger 1	0.040
C1qa	complement component 1, q subcomponent, alpha polypeptide	0.040	Mouse
Ednra	endothelin receptor type A	0.040
Btbd17	BTB (POZ) domain containing 17	0.040
F2r	coagulation factor II (thrombin) receptor	0.040
Rcc2	regulator of chromosome condensation 2	0.040
Pax8	paired box gene 8	0.040
Bcl10	B-cell leukemia/lymphoma 10	0.040
Notch3	Notch gene homolog 3 (Drosophila)	0.040
Lta	lymphotoxin A	0.040
Lgals3	lectin, galactose binding, soluble 3	0.040
Ogfr	opioid growth factor receptor	0.040
Myo10	myosin X	0.040
Sdpr	serum deprivation response	0.040
Frmd6	FERM domain containing 6	0.040
Tbx1	T-box 1	0.039
Lrig1	leucine-rich repeats and immunoglobulin-like domains 1	0.039
Id3	inhibitor of DNA binding 3	0.039
Sh2b3	SH2B adaptor protein 3	0.039
Cdkn1c	cyclin-dependent kinase inhibitor 1C (P57)	0.039	Human
Pik3c2a	phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide	0.039
Foxb1	forkhead box B1	0.039
Tollip	toll interacting protein	0.039
2310002J15Rik	RIKEN cDNA 2310002J15 gene	0.039
Lysmd2	LysM, putative peptidoglycan-binding, domain containing 2	0.039
Enc1	ectodermal-neural cortex 1	0.039
Gnrhr	gonadotropin releasing hormone receptor	0.039
Usp25	ubiquitin specific peptidase 25	0.039
Rfk	riboflavin kinase	0.039
Sost	sclerostin	0.039
Ncoa2	nuclear receptor coactivator 2	0.039
Pde1b	phosphodiesterase 1B, Ca2+-calmodulin dependent	0.038
Itgb1bp3	integrin beta 1 binding protein 3	0.038
Casp3	caspase 3	0.038
Etv5	ets variant gene 5	0.038
Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)	0.038
Ticam1	toll-like receptor adaptor molecule 1	0.038
Msr1	macrophage scavenger receptor 1	0.038
Rbpms	RNA binding protein gene with multiple splicing	0.038
Birc3	baculoviral IAP repeat-containing 3	0.038
Arhgdib	Rho, GDP dissociation inhibitor (GDI) beta	0.038
Col11a2	collagen, type XI, alpha 2	0.038
Folr2	folate receptor 2 (fetal)	0.038
Slc35e4	solute carrier family 35, member E4	0.038
Sfpi1	SFFV proviral integration 1	0.037
Prdx6	peroxiredoxin 6	0.037
St3gal2	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	0.037
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.037
Ppm1b	protein phosphatase 1B, magnesium dependent, beta isoform	0.037	Fly
Swap70	SWA-70 protein	0.037
Lsp1	lymphocyte specific 1	0.037
Nsg1	neuron specific gene family member 1	0.037
Cd68	CD68 antigen	0.037
Gata5	GATA binding protein 5	0.037
Prkd3	protein kinase D3	0.037
Hmx3	H6 homeobox 3	0.037
Smad4	MAD homolog 4 (Drosophila)	0.037
Tead3	TEA domain family member 3	0.037
Ccr7	chemokine (C-C motif) receptor 7	0.037
Dcaf12	DDB1 and CUL4 associated factor 12	0.037
Lsm14a	LSM14 homolog A (SCD6, S. cerevisiae)	0.037
Slc30a1	solute carrier family 30 (zinc transporter), member 1	0.037
Vav1	vav 1 oncogene	0.037
Rfwd2	ring finger and WD repeat domain 2	0.037
Csrp2bp	cysteine and glycine-rich protein 2 binding protein	0.037
Tspyl1	testis-specific protein, Y-encoded-like 1	0.037
Add1	adducin 1 (alpha)	0.037
Rps3	ribosomal protein S3	0.037
Sgcg	sarcoglycan, gamma (dystrophin-associated glycoprotein)	0.037
Wipf1	WAS/WASL interacting protein family, member 1	0.037
Gm3776	predicted gene 3776	0.037
Bcl2l1	BCL2-like 1	0.037
Hsf1	heat shock factor 1	0.037
Pax6	paired box gene 6	0.036
Nfib	nuclear factor I/B	0.036
Ankrd33b	ankyrin repeat domain 33B	0.036
Lrfn1	leucine rich repeat and fibronectin type III domain containing 1	0.036
Atp8a1	ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1	0.036
Ubd	ubiquitin D	0.036
Gab2	growth factor receptor bound protein 2-associated protein 2	0.036
Rassf1	Ras association (RalGDS/AF-6) domain family member 1	0.036
Foxf2	forkhead box F2	0.036
4921517D21Rik	RIKEN cDNA 4921517D21 gene	0.036
Sh3bp5	SH3-domain binding protein 5 (BTK-associated)	0.036
Wnt10b	wingless related MMTV integration site 10b	0.036
Tnfrsf11b	tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)	0.036
Nppb	natriuretic peptide type B	0.036
Dhh	desert hedgehog	0.036
Ctdsp2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2	0.036
Sertad1	SERTA domain containing 1	0.036
Ebf2	early B-cell factor 2	0.036
Lcp2	lymphocyte cytosolic protein 2	0.036
Tnfrsf14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.036
Dck	deoxycytidine kinase	0.035
Nppc	natriuretic peptide type C	0.035
Trp63	transformation related protein 63	0.035	Mouse Fly
Jph3	junctophilin 3	0.035
Egln1	EGL nine homolog 1 (C. elegans)	0.035
4933407C03Rik	RIKEN cDNA 4933407C03 gene	0.035
Jph2	junctophilin 2	0.035
Atl2	atlastin GTPase 2	0.035
Tll1	tolloid-like	0.035
Rab8b	RAB8B, member RAS oncogene family	0.035
Ucn2	urocortin 2	0.035
Irg1	immunoresponsive gene 1	0.035
Camk2d	calcium/calmodulin-dependent protein kinase II, delta	0.035
Ppm1a	protein phosphatase 1A, magnesium dependent, alpha isoform	0.035	Fly
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.035
Plscr1	phospholipid scramblase 1	0.035
Rps6ka3	ribosomal protein S6 kinase polypeptide 3	0.035
Rint1	RAD50 interactor 1	0.035
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.035
Fzd4	frizzled homolog 4 (Drosophila)	0.034
Mapk7	mitogen-activated protein kinase 7	0.034
Chst8	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8	0.034
Cartpt	CART prepropeptide	0.034
Ptp4a2	protein tyrosine phosphatase 4a2	0.034
Rtn4rl2	reticulon 4 receptor-like 2	0.034
Dnajb1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.034
Bicd2	bicaudal D homolog 2 (Drosophila)	0.034
Fam89a	family with sequence similarity 89, member A	0.034
Ptprg	protein tyrosine phosphatase, receptor type, G	0.034
Vav2	vav 2 oncogene	0.034
Acta1	actin, alpha 1, skeletal muscle	0.034
Grxcr1	glutaredoxin, cysteine rich 1	0.034
Rbp7	retinol binding protein 7, cellular	0.034	Mouse
Sh3bp1	SH3-domain binding protein 1	0.034
Mobkl2a	MOB1, Mps One Binder kinase activator-like 2A (yeast)	0.034
Maff	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)	0.034
Tjp2	tight junction protein 2	0.034
Pacs2	phosphofurin acidic cluster sorting protein 2	0.034
Cdca4	cell division cycle associated 4	0.034
Plekhg6	pleckstrin homology domain containing, family G (with RhoGef domain) member 6	0.034
Rhob	ras homolog gene family, member B	0.034
Gab1	growth factor receptor bound protein 2-associated protein 1	0.034
Prkar2a	protein kinase, cAMP dependent regulatory, type II alpha	0.034	Human Mouse
Lpl	lipoprotein lipase	0.034
Snn	stannin	0.034
Trex2	three prime repair exonuclease 2	0.034
Plagl2	pleiomorphic adenoma gene-like 2	0.033
Zic1	zinc finger protein of the cerebellum 1	0.033
Tmem88	transmembrane protein 88	0.033
Gprc5b	G protein-coupled receptor, family C, group 5, member B	0.033
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.033
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.033
Phc2	polyhomeotic-like 2 (Drosophila)	0.033
Pml	promyelocytic leukemia	0.033
Ell	elongation factor RNA polymerase II	0.033
Yes1	Yamaguchi sarcoma viral (v-yes) oncogene homolog 1	0.033	Mouse
Evi2a	ecotropic viral integration site 2a	0.033
Kctd10	potassium channel tetramerisation domain containing 10	0.033
Zfp651	zinc finger protein 651	0.033
Raf1	v-raf-leukemia viral oncogene 1	0.033
Dynlt1b	dynein light chain Tctex-type 1D	0.033
Laptm5	lysosomal-associated protein transmembrane 5	0.033
Irf2bp1	interferon regulatory factor 2 binding protein 1	0.033
Ccr10	chemokine (C-C motif) receptor 10	0.033
Hr	hairless	0.033
Fam101b	family with sequence similarity 101, member B	0.033
Adcy1	adenylate cyclase 1	0.033
Gpr182	G protein-coupled receptor 182	0.033
Tspan14	tetraspanin 14	0.033
Mast2	microtubule associated serine/threonine kinase 2	0.033
Cpd	carboxypeptidase D	0.033
Rhoj	ras homolog gene family, member J	0.033
Plxna2	plexin A2	0.033
Synrg	synergin, gamma	0.033
Folr4	folate receptor 4 (delta)	0.032
Ccnl1	cyclin L1	0.032
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.032
Hdgf	hepatoma-derived growth factor	0.032
Ebi3	Epstein-Barr virus induced gene 3	0.032
Irx3	Iroquois related homeobox 3 (Drosophila)	0.032
Ptpro	protein tyrosine phosphatase, receptor type, O	0.032	Mouse
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.032
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.032
Aplp2	amyloid beta (A4) precursor-like protein 2	0.032
Drd1a	dopamine receptor D1A	0.032
Foxf1a	forkhead box F1a	0.032
Csnk1d	casein kinase 1, delta	0.032
Trib3	tribbles homolog 3 (Drosophila)	0.032
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.032
Mosc1	MOCO sulphurase C-terminal domain containing 1	0.032
Unc119b	unc-119 homolog B (C. elegans)	0.032
Caskin2	CASK-interacting protein 2	0.032
Lyz2	lysozyme 2	0.032
Plin4	perilipin 4	0.032
Ahsa2	AHA1, activator of heat shock protein ATPase homolog 2 (yeast)	0.032
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.032
Foxn1	forkhead box N1	0.032
Tyrobp	TYRO protein tyrosine kinase binding protein	0.032
Shoc2	soc-2 (suppressor of clear) homolog (C. elegans)	0.032
Snta1	syntrophin, acidic 1	0.032
Vps37b	vacuolar protein sorting 37B (yeast)	0.032
Mt2	metallothionein 2	0.031
Glipr2	GLI pathogenesis-related 2	0.031
Ngf	nerve growth factor	0.031
Ccndbp1	cyclin D-type binding-protein 1	0.031
Plekho1	pleckstrin homology domain containing, family O member 1	0.031
Mpzl2	myelin protein zero-like 2	0.031
H2afx	H2A histone family, member X	0.031
Hmha1	histocompatibility (minor) HA-1	0.031
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.031
Ncs1	neuronal calcium sensor 1	0.031
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.031
Atp2a1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.031
Csrnp1	cysteine-serine-rich nuclear protein 1	0.031
Map3k5	mitogen-activated protein kinase kinase kinase 5	0.031
Ccl8	chemokine (C-C motif) ligand 8	0.031
Aim1	absent in melanoma 1	0.031
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.031	Human
Ncf2	neutrophil cytosolic factor 2	0.031