IMP: Integrative Multi-species Prediction

Mus musculus

19 genes annotated in mouse

meiotic chromosome segregation

The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "meiotic chromosome segregation"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "meiotic chromosome segregation" (in gray)

Name	Description	Probability	Func Analog Organism
Brca1	breast cancer 1	0.996
Brca2	breast cancer 2	0.980
Apc	adenomatosis polyposis coli	0.874
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.725
C330027C09Rik	RIKEN cDNA C330027C09 gene	0.719
Ccna2	cyclin A2	0.599
Ccnb1	cyclin B1	0.521
Actr3	ARP3 actin-related protein 3 homolog (yeast)	0.497
Wdhd1	WD repeat and HMG-box DNA binding protein 1	0.475	Worm
Nek2	NIMA (never in mitosis gene a)-related expressed kinase 2	0.466
Mis18bp1	MIS18 binding protein 1	0.464
Smc1a	structural maintenance of chromosomes 1A	0.452
Ezh2	enhancer of zeste homolog 2 (Drosophila)	0.402
Rad21	RAD21 homolog (S. pombe)	0.401	Worm
Smad4	MAD homolog 4 (Drosophila)	0.383
Pola1	polymerase (DNA directed), alpha 1	0.357
Smc3	structural maintenace of chromosomes 3	0.335	Yeast
Plk4	polo-like kinase 4 (Drosophila)	0.321
Atm	ataxia telangiectasia mutated homolog (human)	0.320	Worm
Mcm4	minichromosome maintenance deficient 4 homolog (S. cerevisiae)	0.309
Trp53	transformation related protein 53	0.296	Worm
Incenp	inner centromere protein	0.293
Cdc7	cell division cycle 7 (S. cerevisiae)	0.288
Rad51ap1	RAD51 associated protein 1	0.286
Pten	phosphatase and tensin homolog	0.271
Mybl2	myeloblastosis oncogene-like 2	0.262
Cdc20	cell division cycle 20 homolog (S. cerevisiae)	0.248
Trim59	tripartite motif-containing 59	0.238
Cenpe	centromere protein E	0.224
Dlgap5	discs, large (Drosophila) homolog-associated protein 5	0.218
Prc1	protein regulator of cytokinesis 1	0.213
Orc1	origin recognition complex, subunit 1	0.203
Blm	Bloom syndrome, RecQ helicase-like	0.199	Worm
Ccnb2	cyclin B2	0.199
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.189
Anln	anillin, actin binding protein	0.189
Ccnf	cyclin F	0.181
Pcna	proliferating cell nuclear antigen	0.177
Ncaph	non-SMC condensin I complex, subunit H	0.173
Prkdc	protein kinase, DNA activated, catalytic polypeptide	0.172
Kif11	kinesin family member 11	0.155
Stil	Scl/Tal1 interrupting locus	0.153
Hells	helicase, lymphoid specific	0.149
Ppp1cb	protein phosphatase 1, catalytic subunit, beta isoform	0.146
Rb1	retinoblastoma 1	0.143
Kif22	kinesin family member 22	0.139
Kif20a	kinesin family member 20A	0.136
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.126	Worm
Cdk1	cyclin-dependent kinase 1	0.125
Mad2l1	MAD2 mitotic arrest deficient-like 1 (yeast)	0.120
Ctnnb1	catenin (cadherin associated protein), beta 1	0.117
Nusap1	nucleolar and spindle associated protein 1	0.116
Mcm2	minichromosome maintenance deficient 2 mitotin (S. cerevisiae)	0.115
Kif4	kinesin family member 4	0.112	Fly
Msh2	mutS homolog 2 (E. coli)	0.111
Mdm2	transformed mouse 3T3 cell double minute 2	0.105
Racgap1	Rac GTPase-activating protein 1	0.105
Smc4	structural maintenance of chromosomes 4	0.103
Rbl1	retinoblastoma-like 1 (p107)	0.098
Aurkb	aurora kinase B	0.097
Haus6	HAUS augmin-like complex, subunit 6	0.095
Vegfa	vascular endothelial growth factor A	0.095
Spag5	sperm associated antigen 5	0.094
Cdca8	cell division cycle associated 8	0.092
Mphosph9	M-phase phosphoprotein 9	0.088
Cdt1	chromatin licensing and DNA replication factor 1	0.088
Mcm3	minichromosome maintenance deficient 3 (S. cerevisiae)	0.087
Pold1	polymerase (DNA directed), delta 1, catalytic subunit	0.085
Pafah1b1	platelet-activating factor acetylhydrolase, isoform 1b, subunit 1	0.082
Capza1	capping protein (actin filament) muscle Z-line, alpha 1	0.081
Rfc1	replication factor C (activator 1) 1	0.079
Plk1	polo-like kinase 1 (Drosophila)	0.079	Yeast Worm
Cdk2	cyclin-dependent kinase 2	0.078
Ect2	ect2 oncogene	0.076
Tmpo	thymopoietin	0.072
Atr	ataxia telangiectasia and Rad3 related	0.071	Fly
Kif2c	kinesin family member 2C	0.070	Worm
Pds5a	PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)	0.070	Worm
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.070
Cdca5	cell division cycle associated 5	0.067
Ttk	Ttk protein kinase	0.062	Zebrafish Fly
Foxm1	forkhead box M1	0.062
Itga3	integrin alpha 3	0.061
Cenpk	centromere protein K	0.060
Dek	DEK oncogene (DNA binding)	0.059
Ccnd1	cyclin D1	0.059
Rad50	RAD50 homolog (S. cerevisiae)	0.059
Ckap2	cytoskeleton associated protein 2	0.059
Vapa	vesicle-associated membrane protein, associated protein A	0.059
Aspm	asp (abnormal spindle)-like, microcephaly associated (Drosophila)	0.058
Cdc6	cell division cycle 6 homolog (S. cerevisiae)	0.057
Rara	retinoic acid receptor, alpha	0.056
Mms22l	MMS22-like, DNA repair protein	0.055
Ube2t	ubiquitin-conjugating enzyme E2T (putative)	0.055
Top2a	topoisomerase (DNA) II alpha	0.055
Smarcd1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.054
Cenpa	centromere protein A	0.054
Lbr	lamin B receptor	0.054
Pds5b	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.053	Worm
Chek1	checkpoint kinase 1 homolog (S. pombe)	0.051
Cdc45	cell division cycle 45 homolog (S. cerevisiae)	0.051
Eri2	exoribonuclease 2	0.050
Mns1	meiosis-specific nuclear structural protein 1	0.050
Vhl	von Hippel-Lindau tumor suppressor	0.050
Bub1	budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)	0.050
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.049
Lin9	lin-9 homolog (C. elegans)	0.047
Per2	period homolog 2 (Drosophila)	0.047
Trp63	transformation related protein 63	0.046	Worm
Nbn	nibrin	0.046
Cdc25c	cell division cycle 25 homolog C (S. pombe)	0.046
Smc2	structural maintenance of chromosomes 2	0.043
Pms2	postmeiotic segregation increased 2 (S. cerevisiae)	0.043
Notch2	Notch gene homolog 2 (Drosophila)	0.043
Hist1h2bc	histone cluster 1, H2bc	0.042
Slbp	stem-loop binding protein	0.042
Sass6	spindle assembly 6 homolog (C. elegans)	0.041
Haus5	HAUS augmin-like complex, subunit 5	0.041
Rint1	RAD50 interactor 1	0.041
Sept7	septin 7	0.040	Mouse
Sumo1	SMT3 suppressor of mif two 3 homolog 1 (yeast)	0.040
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.040
Hif1a	hypoxia inducible factor 1, alpha subunit	0.037
Kit	kit oncogene	0.037
Ctcf	CCCTC-binding factor	0.036
Atrx	alpha thalassemia/mental retardation syndrome X-linked homolog (human)	0.036
Per1	period homolog 1 (Drosophila)	0.035
Nuf2	NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)	0.035
Dck	deoxycytidine kinase	0.034
Hnrnph2	heterogeneous nuclear ribonucleoprotein H2	0.034
Ttf2	transcription termination factor, RNA polymerase II	0.034
Morf4l2	mortality factor 4 like 2	0.034
B230308N11Rik	RIKEN cDNA B230308N11 gene	0.034
Rpa1	replication protein A1	0.033
Ncapg2	non-SMC condensin II complex, subunit G2	0.033
Pole2	polymerase (DNA directed), epsilon 2 (p59 subunit)	0.032
Asf1b	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	0.032
Etaa1	Ewing's tumor-associated antigen 1	0.032
Recql	RecQ protein-like	0.032
Ccdc99	coiled-coil domain containing 99	0.032
Tcf19	transcription factor 19	0.032
Rxra	retinoid X receptor alpha	0.031
Ckap5	cytoskeleton associated protein 5	0.031
Cdca7	cell division cycle associated 7	0.030
Arpc2	actin related protein 2/3 complex, subunit 2	0.030
Gtse1	G two S phase expressed protein 1	0.029
Iqgap3	IQ motif containing GTPase activating protein 3	0.029
Terf1	telomeric repeat binding factor 1	0.029
Capza2	capping protein (actin filament) muscle Z-line, alpha 2	0.029
Lmnb1	lamin B1	0.028
Mki67	antigen identified by monoclonal antibody Ki 67	0.028
Cnot1	CCR4-NOT transcription complex, subunit 1	0.028
Hmgb2	high mobility group box 2	0.028
E2f8	E2F transcription factor 8	0.028
Cep55	centrosomal protein 55	0.028
Psip1	PC4 and SFRS1 interacting protein 1	0.028
Rttn	rotatin	0.027
Ube2c	ubiquitin-conjugating enzyme E2C	0.027
Dnajc9	DnaJ (Hsp40) homolog, subfamily C, member 9	0.027
Calm1	calmodulin 1	0.027
Ppp1ca	protein phosphatase 1, catalytic subunit, alpha isoform	0.027
Anp32e	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E	0.027
Mecp2	methyl CpG binding protein 2	0.026
Mbd4	methyl-CpG binding domain protein 4	0.026
Mnd1	meiotic nuclear divisions 1 homolog (S. cerevisiae)	0.026
Birc5	baculoviral IAP repeat-containing 5	0.026
Rap1b	RAS related protein 1b	0.025
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.025	Worm
Ppp2ca	protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform	0.025
Cttn	cortactin	0.025
Meox2	mesenchyme homeobox 2	0.024
2810417H13Rik	RIKEN cDNA 2810417H13 gene	0.024
Ube2d2	ubiquitin-conjugating enzyme E2D 2	0.024
H2afx	H2A histone family, member X	0.024
Aurka	aurora kinase A	0.024	Yeast
Rad51	RAD51 homolog (S. cerevisiae)	0.023	Worm
Hist1h1b	histone cluster 1, H1b	0.023
Ilk	integrin linked kinase	0.023
Eif4g2	eukaryotic translation initiation factor 4, gamma 2	0.023
Tipin	timeless interacting protein	0.023
Ccdc77	coiled-coil domain containing 77	0.023
Xpo1	exportin 1, CRM1 homolog (yeast)	0.023
Cenpf	centromere protein F	0.023
Vbp1	von Hippel-Lindau binding protein 1	0.023
Fgfr2	fibroblast growth factor receptor 2	0.022
Igh	immunoglobulin heavy chain complex	0.022
Sfn	stratifin	0.022
Dtl	denticleless homolog (Drosophila)	0.022
Ddx46	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46	0.022
Bard1	BRCA1 associated RING domain 1	0.022
Eif4g1	eukaryotic translation initiation factor 4, gamma 1	0.021
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.021
Mapk8	mitogen-activated protein kinase 8	0.021
Lancl2	LanC (bacterial lantibiotic synthetase component C)-like 2	0.021
Tsc1	tuberous sclerosis 1	0.021
Ncapd3	non-SMC condensin II complex, subunit D3	0.020
Kif23	kinesin family member 23	0.020	Fly
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.020
Nptn	neuroplastin	0.020
3110003A17Rik	RIKEN cDNA 3110003A17 gene	0.020
Tcf3	transcription factor 3	0.020
Hnrnpr	heterogeneous nuclear ribonucleoprotein R	0.020
Dna2	DNA replication helicase 2 homolog (yeast)	0.020
Hmmr	hyaluronan mediated motility receptor (RHAMM)	0.019
Stk4	serine/threonine kinase 4	0.019
Pum2	pumilio 2 (Drosophila)	0.019
Hmgb1	high mobility group box 1	0.019
Ccne1	cyclin E1	0.019
Tsc2	tuberous sclerosis 2	0.018
Aqr	aquarius	0.018
Wrn	Werner syndrome homolog (human)	0.018
Casp8ap2	caspase 8 associated protein 2	0.018
Actr2	ARP2 actin-related protein 2 homolog (yeast)	0.018
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.018
Gdi2	guanosine diphosphate (GDP) dissociation inhibitor 2	0.017
Cntrob	centrobin, centrosomal BRCA2 interacting protein	0.017
Hdac2	histone deacetylase 2	0.017
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.017
H3f3a	H3 histone, family 3A	0.016
Uhrf1	ubiquitin-like, containing PHD and RING finger domains, 1	0.016
2610039C10Rik	RIKEN cDNA 2610039C10 gene	0.016
Fen1	flap structure specific endonuclease 1	0.016
Gna11	guanine nucleotide binding protein, alpha 11	0.016
Rpl7	ribosomal protein L7	0.016
Uba2	ubiquitin-like modifier activating enzyme 2	0.016
Psen1	presenilin 1	0.015
Tacc3	transforming, acidic coiled-coil containing protein 3	0.015
Bub1b	budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)	0.015	Fly
Cdca7l	cell division cycle associated 7 like	0.015
Api5	apoptosis inhibitor 5	0.015
Zfp207	zinc finger protein 207	0.015
Cbx5	chromobox homolog 5 (Drosophila HP1a)	0.015
Bcl2	B-cell leukemia/lymphoma 2	0.015
Cenpn	centromere protein N	0.015
Mtf2	metal response element binding transcription factor 2	0.015
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.015
Nanog	Nanog homeobox	0.015
Rcc1	regulator of chromosome condensation 1	0.015
Suz12	suppressor of zeste 12 homolog (Drosophila)	0.014
Fam49b	family with sequence similarity 49, member B	0.014
Gmnn	geminin	0.014
Rad18	RAD18 homolog (S. cerevisiae)	0.014
Hnrpll	heterogeneous nuclear ribonucleoprotein L-like	0.014
Ncapd2	non-SMC condensin I complex, subunit D2	0.014
Sox4	SRY-box containing gene 4	0.014
Chek2	CHK2 checkpoint homolog (S. pombe)	0.014	Worm
Hnrnpa2b1	heterogeneous nuclear ribonucleoprotein A2/B1	0.014
Nucks1	nuclear casein kinase and cyclin-dependent kinase substrate 1	0.014
Hr	hairless	0.014
Gja1	gap junction protein, alpha 1	0.014
Smad2	MAD homolog 2 (Drosophila)	0.014
Mcm7	minichromosome maintenance deficient 7 (S. cerevisiae)	0.014
Mtpn	myotrophin	0.014
Ces1d	carboxylesterase 1D	0.014
Huwe1	HECT, UBA and WWE domain containing 1	0.013
Wipf1	WAS/WASL interacting protein family, member 1	0.013
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.013
Trim37	tripartite motif-containing 37	0.013
Nvl	nuclear VCP-like	0.013
Wapal	wings apart-like homolog (Drosophila)	0.013
Cd151	CD151 antigen	0.013
Rrm1	ribonucleotide reductase M1	0.013
Zeb1	zinc finger E-box binding homeobox 1	0.013
Smc6	structural maintenance of chromosomes 6	0.013
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.013
Smad3	MAD homolog 3 (Drosophila)	0.013
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.013
Eif2a	eukaryotic translation initiation factor 2A	0.013
Nap1l1	nucleosome assembly protein 1-like 1	0.013
Mybl1	myeloblastosis oncogene-like 1	0.013
Usp22	ubiquitin specific peptidase 22	0.013
Fancm	Fanconi anemia, complementation group M	0.012	Human
Nup93	nucleoporin 93	0.012
Rrm2	ribonucleotide reductase M2	0.012
Fam76b	family with sequence similarity 76, member B	0.012
Pask	PAS domain containing serine/threonine kinase	0.012
Usp1	ubiquitin specific peptidase 1	0.012
Rap1a	RAS-related protein-1a	0.012
Ndc80	NDC80 homolog, kinetochore complex component (S. cerevisiae)	0.012
Lsm14a	LSM14 homolog A (SCD6, S. cerevisiae)	0.012
Dlgap4	discs, large homolog-associated protein 4 (Drosophila)	0.012
Chaf1b	chromatin assembly factor 1, subunit B (p60)	0.012
Dstn	destrin	0.012
Ret	ret proto-oncogene	0.012
Scaf11	SR-related CTD-associated factor 11	0.012
Tsg101	tumor susceptibility gene 101	0.012
Ces1e	carboxylesterase 1E	0.012	Fly
Egln1	EGL nine homolog 1 (C. elegans)	0.012
Nup85	nucleoporin 85	0.012
Cyfip1	cytoplasmic FMR1 interacting protein 1	0.012
Zfp101	zinc finger protein 101	0.012
Xrcc2	X-ray repair complementing defective repair in Chinese hamster cells 2	0.012
Mcl1	myeloid cell leukemia sequence 1	0.011
Cks2	CDC28 protein kinase regulatory subunit 2	0.011
Diap3	diaphanous homolog 3 (Drosophila)	0.011
2610101N10Rik	RIKEN cDNA 2610101N10 gene	0.011
Matr3	matrin 3	0.011
Rfc3	replication factor C (activator 1) 3	0.011
Nasp	nuclear autoantigenic sperm protein (histone-binding)	0.011
Trip13	thyroid hormone receptor interactor 13	0.011
Aicda	activation-induced cytidine deaminase	0.011
Tert	telomerase reverse transcriptase	0.011
Braf	Braf transforming gene	0.011
Npat	nuclear protein in the AT region	0.011
Agfg1	ArfGAP with FG repeats 1	0.011
Rbbp7	retinoblastoma binding protein 7	0.011
Ptch1	patched homolog 1	0.011
Tmsb4x	thymosin, beta 4, X chromosome	0.011
Men1	multiple endocrine neoplasia 1	0.011
Tdp2	tyrosyl-DNA phosphodiesterase 2	0.011
Cdkn3	cyclin-dependent kinase inhibitor 3	0.011
Col1a1	collagen, type I, alpha 1	0.011
Dsn1	DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)	0.011
Hnrnpk	heterogeneous nuclear ribonucleoprotein K	0.011	Worm
G2e3	G2/M-phase specific E3 ubiquitin ligase	0.011
Ar	androgen receptor	0.011
Myef2	myelin basic protein expression factor 2, repressor	0.010
Dppa4	developmental pluripotency associated 4	0.010
Ces1f	carboxylesterase 1F	0.010	Fly
Nedd1	neural precursor cell expressed, developmentally down-regulated gene 1	0.010
Chtf18	CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)	0.010
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.010
Lmnb2	lamin B2	0.010
Ung	uracil DNA glycosylase	0.010
Capzb	capping protein (actin filament) muscle Z-line, beta	0.010
Sin3a	transcriptional regulator, SIN3A (yeast)	0.010
Atp6ap2	ATPase, H+ transporting, lysosomal accessory protein 2	0.010
Melk	maternal embryonic leucine zipper kinase	0.010
Haus4	HAUS augmin-like complex, subunit 4	0.010