IMP: Integrative Multi-species Prediction

Mus musculus

4 genes annotated in mouse

positive regulation of chromosome segregation

GO:0051984

Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of chromosome segregation"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "positive regulation of chromosome segregation" (in gray)

Name	Description	Probability	Func Analog Organism
Trp53	transformation related protein 53	0.996
Ctnnb1	catenin (cadherin associated protein), beta 1	0.977
Ube2c	ubiquitin-conjugating enzyme E2C	0.927	Fly
Ccna2	cyclin A2	0.921
Bub1b	budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)	0.914
Pten	phosphatase and tensin homolog	0.901
Cdc20	cell division cycle 20 homolog (S. cerevisiae)	0.854	Yeast Fly
Plk1	polo-like kinase 1 (Drosophila)	0.837	Human
Ccnb2	cyclin B2	0.828
Ccnb1	cyclin B1	0.748	Human
Cdk1	cyclin-dependent kinase 1	0.744
Apc	adenomatosis polyposis coli	0.732
Ccnf	cyclin F	0.691
Aurkb	aurora kinase B	0.622
Cdc25c	cell division cycle 25 homolog C (S. pombe)	0.591
Cdca5	cell division cycle associated 5	0.561
Mcm3	minichromosome maintenance deficient 3 (S. cerevisiae)	0.546
Kif2c	kinesin family member 2C	0.544
Fzr1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.544	Yeast Fly
Cdca8	cell division cycle associated 8	0.521
Prc1	protein regulator of cytokinesis 1	0.411
Mki67	antigen identified by monoclonal antibody Ki 67	0.363
Nek2	NIMA (never in mitosis gene a)-related expressed kinase 2	0.352
Kif22	kinesin family member 22	0.301
Kif4	kinesin family member 4	0.289
Axin1	axin 1	0.275
Hmmr	hyaluronan mediated motility receptor (RHAMM)	0.270
Uhrf1	ubiquitin-like, containing PHD and RING finger domains, 1	0.262
Cenpa	centromere protein A	0.249
Kif20a	kinesin family member 20A	0.249
H2afx	H2A histone family, member X	0.244
Ckap2	cytoskeleton associated protein 2	0.235
Psen1	presenilin 1	0.230
Ckap2l	cytoskeleton associated protein 2-like	0.225
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.224
Cdkn3	cyclin-dependent kinase inhibitor 3	0.222
Cenpf	centromere protein F	0.203
Usp9x	ubiquitin specific peptidase 9, X chromosome	0.188
Birc5	baculoviral IAP repeat-containing 5	0.181
Lmnb1	lamin B1	0.176
Dlgap5	discs, large (Drosophila) homolog-associated protein 5	0.169
Melk	maternal embryonic leucine zipper kinase	0.167
D2Ertd750e	DNA segment, Chr 2, ERATO Doi 750, expressed	0.159
Rcc1	regulator of chromosome condensation 1	0.152
Fam64a	family with sequence similarity 64, member A	0.151
Gtse1	G two S phase expressed protein 1	0.149
Aurka	aurora kinase A	0.143
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.140
Brca1	breast cancer 1	0.132
Rrm2	ribonucleotide reductase M2	0.130
Incenp	inner centromere protein	0.129
Trim28	tripartite motif-containing 28	0.125
Ppp4c	protein phosphatase 4, catalytic subunit	0.119
Mdm2	transformed mouse 3T3 cell double minute 2	0.117
Spag5	sperm associated antigen 5	0.113
Aspm	asp (abnormal spindle)-like, microcephaly associated (Drosophila)	0.108
Kif11	kinesin family member 11	0.106
Wbp2	WW domain binding protein 2	0.103
Nuf2	NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)	0.101
Stil	Scl/Tal1 interrupting locus	0.099
Espl1	extra spindle poles-like 1 (S. cerevisiae)	0.098
E2f1	E2F transcription factor 1	0.095
Atf2	activating transcription factor 2	0.092
Cenpn	centromere protein N	0.088
Asf1b	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	0.084
Ccnd1	cyclin D1	0.084
Kif23	kinesin family member 23	0.081
Sgol1	shugoshin-like 1 (S. pombe)	0.080
Ncapg	non-SMC condensin I complex, subunit G	0.077
Ccne1	cyclin E1	0.075
Mybl2	myeloblastosis oncogene-like 2	0.074
Ndc80	NDC80 homolog, kinetochore complex component (S. cerevisiae)	0.074
Rangap1	RAN GTPase activating protein 1	0.068
Gsg2	germ cell-specific gene 2	0.067
Mta2	metastasis-associated gene family, member 2	0.065
Lrp6	low density lipoprotein receptor-related protein 6	0.064
Nf2	neurofibromatosis 2	0.062
Bmi1	Bmi1 polycomb ring finger oncogene	0.061
Ska1	spindle and kinetochore associated complex subunit 1	0.061
2810417H13Rik	RIKEN cDNA 2810417H13 gene	0.059
Depdc1b	DEP domain containing 1B	0.058
Ccdc99	coiled-coil domain containing 99	0.056
Kit	kit oncogene	0.054
Cdca2	cell division cycle associated 2	0.052
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.052
Idh3g	isocitrate dehydrogenase 3 (NAD+), gamma	0.051
Ruvbl2	RuvB-like protein 2	0.051
Cenpe	centromere protein E	0.048
E2f8	E2F transcription factor 8	0.048
Prmt5	protein arginine N-methyltransferase 5	0.047
Smad4	MAD homolog 4 (Drosophila)	0.047
Dazap1	DAZ associated protein 1	0.044
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.042
Fam83d	family with sequence similarity 83, member D	0.041
Mxd3	Max dimerization protein 3	0.040
Diap3	diaphanous homolog 3 (Drosophila)	0.038
Ddx46	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46	0.038
Hcfc1	host cell factor C1	0.037
Racgap1	Rac GTPase-activating protein 1	0.037
Cdk2	cyclin-dependent kinase 2	0.036
Bckdha	branched chain ketoacid dehydrogenase E1, alpha polypeptide	0.034
Ercc6l	excision repair cross-complementing rodent repair deficiency complementation group 6 - like	0.033
Sirt2	sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae)	0.033
Exo1	exonuclease 1	0.033
Mbd3	methyl-CpG binding domain protein 3	0.032
Eme1	essential meiotic endonuclease 1 homolog 1 (S. pombe)	0.032
Tk1	thymidine kinase 1	0.032
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.031
Cdca4	cell division cycle associated 4	0.031
Mis18bp1	MIS18 binding protein 1	0.031
Prr11	proline rich 11	0.030
Rsbn1	rosbin, round spermatid basic protein 1	0.030
Smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.029
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.029
Vars	valyl-tRNA synthetase	0.029
Tcf3	transcription factor 3	0.028
Ppp3cb	protein phosphatase 3, catalytic subunit, beta isoform	0.028
Mad2l1	MAD2 mitotic arrest deficient-like 1 (yeast)	0.027
Kntc1	kinetochore associated 1	0.027
Immt	inner membrane protein, mitochondrial	0.026
Esco2	establishment of cohesion 1 homolog 2 (S. cerevisiae)	0.026
Dyrk1a	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a	0.025
Tcof1	Treacher Collins Franceschetti syndrome 1, homolog	0.025
Tpx2	TPX2, microtubule-associated protein homolog (Xenopus laevis)	0.025
Spc24	SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)	0.025
Gipc1	GIPC PDZ domain containing family, member 1	0.025
Nolc1	nucleolar and coiled-body phosphoprotein 1	0.025
Pdpk1	3-phosphoinositide dependent protein kinase 1	0.024
E2f7	E2F transcription factor 7	0.024
Rad54l	RAD54 like (S. cerevisiae)	0.024
F630043A04Rik	RIKEN cDNA F630043A04 gene	0.023
Ncaph	non-SMC condensin I complex, subunit H	0.023
Rad51ap1	RAD51 associated protein 1	0.023
Men1	multiple endocrine neoplasia 1	0.022
Foxo3	forkhead box O3	0.022
D10Jhu81e	DNA segment, Chr 10, Johns Hopkins University 81 expressed	0.022
Gm2223	predicted pseudogene 2223	0.022
Kat2a	K(lysine) acetyltransferase 2A	0.022
Bub1	budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)	0.022
Tsc1	tuberous sclerosis 1	0.021
Kif18b	kinesin family member 18B	0.021
Trim23	tripartite motif-containing 23	0.021
Rmnd5a	required for meiotic nuclear division 5 homolog A (S. cerevisiae)	0.020
Cenpi	centromere protein I	0.019
Zmym2	zinc finger, MYM-type 2	0.019
Rb1	retinoblastoma 1	0.019	Human
E130306D19Rik	RIKEN cDNA E130306D19 gene	0.019
Eif5a	eukaryotic translation initiation factor 5A	0.019
Cdc25b	cell division cycle 25 homolog B (S. pombe)	0.019
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.018
Coq9	coenzyme Q9 homolog (yeast)	0.018
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.018
Klhl7	kelch-like 7 (Drosophila)	0.018
Rbl2	retinoblastoma-like 2	0.018
Pum1	pumilio 1 (Drosophila)	0.018
Kitl	kit ligand	0.018
Gsk3b	glycogen synthase kinase 3 beta	0.017	Fly
Arid1a	AT rich interactive domain 1A (SWI-like)	0.017
Fbxo5	F-box protein 5	0.017
Usp15	ubiquitin specific peptidase 15	0.017
Slmap	sarcolemma associated protein	0.017
Dlg1	discs, large homolog 1 (Drosophila)	0.017
Brca2	breast cancer 2	0.017
Smarcc1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.017
Rps6ka5	ribosomal protein S6 kinase, polypeptide 5	0.017
Mcrs1	microspherule protein 1	0.017
Troap	trophinin associated protein	0.016
Hmga1-rs1	high mobility group AT-hook I, related sequence 1	0.016
Clk1	CDC-like kinase 1	0.016
Atf6b	activating transcription factor 6 beta	0.016
Fbxo11	F-box protein 11	0.016
Ppp1cb	protein phosphatase 1, catalytic subunit, beta isoform	0.016
Acot13	acyl-CoA thioesterase 13	0.016
Cad	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	0.016
Ech1	enoyl coenzyme A hydratase 1, peroxisomal	0.016
Fus	fusion, derived from t(12;16) malignant liposarcoma (human)	0.015
Ptch1	patched homolog 1	0.015
Whsc2	Wolf-Hirschhorn syndrome candidate 2 (human)	0.015
Pafah1b2	platelet-activating factor acetylhydrolase, isoform 1b, subunit 2	0.015
Iqgap3	IQ motif containing GTPase activating protein 3	0.015
Surf1	surfeit gene 1	0.015
Ep300	E1A binding protein p300	0.015
Mthfd2	methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase	0.015
Lrwd1	leucine-rich repeats and WD repeat domain containing 1	0.015
Cdc45	cell division cycle 45 homolog (S. cerevisiae)	0.015
Mcm5	minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)	0.015
Top2a	topoisomerase (DNA) II alpha	0.015
Kpna1	karyopherin (importin) alpha 1	0.014
Tsc2	tuberous sclerosis 2	0.014
Depdc1a	DEP domain containing 1a	0.014
Casc5	cancer susceptibility candidate 5	0.014
Vegfb	vascular endothelial growth factor B	0.014
Qk	quaking	0.014
Ncapd2	non-SMC condensin I complex, subunit D2	0.014
Impad1	inositol monophosphatase domain containing 1	0.014
Braf	Braf transforming gene	0.014
Pcbd2	pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2	0.014
Dhx8	DEAH (Asp-Glu-Ala-His) box polypeptide 8	0.014
Csde1	cold shock domain containing E1, RNA binding	0.014
Slc7a5	solute carrier family 7 (cationic amino acid transporter, y+ system), member 5	0.014
Rab10	RAB10, member RAS oncogene family	0.014
Fam126b	family with sequence similarity 126, member B	0.014
Rrp1	ribosomal RNA processing 1 homolog (S. cerevisiae)	0.014
Dtl	denticleless homolog (Drosophila)	0.014
Arid1b	AT rich interactive domain 1B (SWI-like)	0.014
Dnajc4	DnaJ (Hsp40) homolog, subfamily C, member 4	0.014
Notch1	Notch gene homolog 1 (Drosophila)	0.014
Nedd4	neural precursor cell expressed, developmentally down-regulated 4	0.014
Rnf26	ring finger protein 26	0.013
Macf1	microtubule-actin crosslinking factor 1	0.013
Ttk	Ttk protein kinase	0.013
Xpa	xeroderma pigmentosum, complementation group A	0.013
Lmnb2	lamin B2	0.013
Isyna1	myo-inositol 1-phosphate synthase A1	0.013
Casp3	caspase 3	0.013
Hist1h2ao	histone cluster 1, H2ao	0.013
Zfp868	zinc finger protein 868	0.013
Pole	polymerase (DNA directed), epsilon	0.013
Ndufv3	NADH dehydrogenase (ubiquinone) flavoprotein 3	0.013
Cdc25a	cell division cycle 25 homolog A (S. pombe)	0.013
Xpo5	exportin 5	0.013
Senp3	SUMO/sentrin specific peptidase 3	0.013
Bre	brain and reproductive organ-expressed protein	0.012
Wdr26	WD repeat domain 26	0.012
Cdk4	cyclin-dependent kinase 4	0.012
E2f2	E2F transcription factor 2	0.012
Chd7	chromodomain helicase DNA binding protein 7	0.012
Eif4g1	eukaryotic translation initiation factor 4, gamma 1	0.012
Stk11	serine/threonine kinase 11	0.012
Ncoa1	nuclear receptor coactivator 1	0.012
Mgea5	meningioma expressed antigen 5 (hyaluronidase)	0.012
Pptc7	PTC7 protein phosphatase homolog (S. cerevisiae)	0.012
Mmaa	methylmalonic aciduria (cobalamin deficiency) type A	0.012
Chd4	chromodomain helicase DNA binding protein 4	0.012
BC018507	cDNA sequence BC018507	0.012
Pias2	protein inhibitor of activated STAT 2	0.012
Pom121	nuclear pore membrane protein 121	0.012
Mapk8	mitogen-activated protein kinase 8	0.012
Tdg	thymine DNA glycosylase	0.012
Mastl	microtubule associated serine/threonine kinase-like	0.012
Rad51	RAD51 homolog (S. cerevisiae)	0.012
Hif1a	hypoxia inducible factor 1, alpha subunit	0.012
Fos	FBJ osteosarcoma oncogene	0.012
Pbk	PDZ binding kinase	0.012
Ints5	integrator complex subunit 5	0.011
Ppm1b	protein phosphatase 1B, magnesium dependent, beta isoform	0.011
Aldh2	aldehyde dehydrogenase 2, mitochondrial	0.011
Ubtf	upstream binding transcription factor, RNA polymerase I	0.011
Acin1	apoptotic chromatin condensation inducer 1	0.011
2410002F23Rik	RIKEN cDNA 2410002F23 gene	0.011
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.011
Adat3	adenosine deaminase, tRNA-specific 3, TAD2 homolog (S. cerevisiae)	0.011
Crebbp	CREB binding protein	0.011
Plekhj1	pleckstrin homology domain containing, family J member 1	0.011
Tex264	testis expressed gene 264	0.011
Top2b	topoisomerase (DNA) II beta	0.011
Pja2	praja 2, RING-H2 motif containing	0.011
Hccs	holocytochrome c synthetase	0.011
Foxm1	forkhead box M1	0.011
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.011
Fbxw7	F-box and WD-40 domain protein 7	0.011
Cd2bp2	CD2 antigen (cytoplasmic tail) binding protein 2	0.011
Dcaf15	DDB1 and CUL4 associated factor 15	0.011
Atp2c1	ATPase, Ca++-sequestering	0.011
Pold1	polymerase (DNA directed), delta 1, catalytic subunit	0.011
Hagh	hydroxyacyl glutathione hydrolase	0.011
Zbtb45	zinc finger and BTB domain containing 45	0.011
1810020D17Rik	RIKEN cDNA 1810020D17 gene	0.011
Fam54a	family with sequence similarity 54, member A	0.011
Rfc5	replication factor C (activator 1) 5	0.011
Ndrg3	N-myc downstream regulated gene 3	0.011
Tmem131	transmembrane protein 131	0.011
Trip13	thyroid hormone receptor interactor 13	0.011
Myc	myelocytomatosis oncogene	0.011
Tbc1d10b	TBC1 domain family, member 10b	0.011
Wbp11	WW domain binding protein 11	0.010
Ahcyl1	S-adenosylhomocysteine hydrolase-like 1	0.010
Qrich1	glutamine-rich 1	0.010
Oxr1	oxidation resistance 1	0.010
Lsm2	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.010
Mybbp1a	MYB binding protein (P160) 1a	0.010
Zfp654	zinc finger protein 654	0.010
Cbr1	carbonyl reductase 1	0.010