IMP: Integrative Multi-species Prediction

Mus musculus

95 genes annotated in mouse

positive regulation of cell projection organization

Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of cell projection organization"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "positive regulation of cell projection organization" (in gray)

Name	Description	Probability	Func Analog Organism
Dab1	disabled homolog 1 (Drosophila)	0.975
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.966	Mouse
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.956	Mouse
Ptk2	PTK2 protein tyrosine kinase 2	0.934
Src	Rous sarcoma oncogene	0.923	Mouse
Cd44	CD44 antigen	0.885
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.825
Dcc	deleted in colorectal carcinoma	0.819	Rat
Git1	G protein-coupled receptor kinase-interactor 1	0.803
Prnp	prion protein	0.790
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.775	Human Mouse Fly
Robo1	roundabout homolog 1 (Drosophila)	0.743	Human
Apc	adenomatosis polyposis coli	0.724	Human
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.708
Ednrb	endothelin receptor type B	0.703
Pxn	paxillin	0.672
Akt1	thymoma viral proto-oncogene 1	0.666	Fly
Ctnnb1	catenin (cadherin associated protein), beta 1	0.654
Dvl2	dishevelled 2, dsh homolog (Drosophila)	0.638	Mouse
Smad3	MAD homolog 3 (Drosophila)	0.623
L1cam	L1 cell adhesion molecule	0.596
Sox9	SRY-box containing gene 9	0.579
Prkce	protein kinase C, epsilon	0.563
Wnt5a	wingless-related MMTV integration site 5A	0.557
Foxc1	forkhead box C1	0.556
Pou4f3	POU domain, class 4, transcription factor 3	0.555
Flt1	FMS-like tyrosine kinase 1	0.554
Ephb2	Eph receptor B2	0.549
Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.542
Wnt7a	wingless-related MMTV integration site 7A	0.542	Mouse
Neurl1a	neuralized homolog 1A (Drosophila)	0.538
Srcin1	SRC kinase signaling inhibitor 1	0.538
Dbn1	drebrin 1	0.527
Dnm1	dynamin 1	0.523
Vasp	vasodilator-stimulated phosphoprotein	0.513	Fly
Fbn1	fibrillin 1	0.509
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.505	Rat
Itga3	integrin alpha 3	0.495
Pten	phosphatase and tensin homolog	0.484
Abi1	abl-interactor 1	0.473
Odz2	odd Oz/ten-m homolog 2 (Drosophila)	0.466	Mouse
Bdnf	brain derived neurotrophic factor	0.463	Mouse
Fgfr1	fibroblast growth factor receptor 1	0.445
Enah	enabled homolog (Drosophila)	0.419	Fly
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.414
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.403
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.401
Gnb2	guanine nucleotide binding protein (G protein), beta 2	0.397
Plec	plectin	0.386	Fly
Apc2	adenomatosis polyposis coli 2	0.382
Nfib	nuclear factor I/B	0.380
Slit3	slit homolog 3 (Drosophila)	0.373
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.372
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.370
Arhgef11	Rho guanine nucleotide exchange factor (GEF) 11	0.366
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.365
Wnt4	wingless-related MMTV integration site 4	0.361	Mouse
Slit2	slit homolog 2 (Drosophila)	0.358
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.357
Fyn	Fyn proto-oncogene	0.352
Meox2	mesenchyme homeobox 2	0.346
Cacna2d3	calcium channel, voltage-dependent, alpha2/delta subunit 3	0.346
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.345
Arhgdib	Rho, GDP dissociation inhibitor (GDI) beta	0.345
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.335
Eng	endoglin	0.324
Ndel1	nuclear distribution gene E-like homolog 1 (A. nidulans)	0.323
Tgfbr1	transforming growth factor, beta receptor I	0.314
Dvl1	dishevelled, dsh homolog 1 (Drosophila)	0.308
Kcne1l	potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene	0.300
Mapt	microtubule-associated protein tau	0.294
Pacsin1	protein kinase C and casein kinase substrate in neurons 1	0.291	Rat
Akp3	alkaline phosphatase 3, intestine, not Mn requiring	0.290
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.289
Gnao1	guanine nucleotide binding protein, alpha O	0.289
Arhgef7	Rho guanine nucleotide exchange factor (GEF7)	0.281	Human
Vangl2	vang-like 2 (van gogh, Drosophila)	0.278
Nf1	neurofibromatosis 1	0.278
Stra6	stimulated by retinoic acid gene 6	0.277
Ret	ret proto-oncogene	0.274	Human
Adam11	a disintegrin and metallopeptidase domain 11	0.274
Bcar1	breast cancer anti-estrogen resistance 1	0.268
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.266
Dst	dystonin	0.263	Fly
Dok1	docking protein 1	0.256
Acvr1	activin A receptor, type 1	0.253	Mouse
Plxna1	plexin A1	0.253	Mouse
Pak1	p21 protein (Cdc42/Rac)-activated kinase 1	0.248
Cdh2	cadherin 2	0.241	Mouse
Nphp4	nephronophthisis 4 (juvenile) homolog (human)	0.239
Ina	internexin neuronal intermediate filament protein, alpha	0.239	Mouse
Prl6a1	prolactin family 6, subfamily a, member 1	0.239	Mouse
Wnt10b	wingless related MMTV integration site 10b	0.238	Mouse
Onecut1	one cut domain, family member 1	0.238	Mouse
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.236	Rat
Gsk3b	glycogen synthase kinase 3 beta	0.234
Glra1	glycine receptor, alpha 1 subunit	0.234
Ptprf	protein tyrosine phosphatase, receptor type, F	0.234	Mouse Rat
Adam23	a disintegrin and metallopeptidase domain 23	0.233
Arhgef12	Rho guanine nucleotide exchange factor (GEF) 12	0.232
Ccdc24	coiled-coil domain containing 24	0.223
Ntf3	neurotrophin 3	0.222	Mouse
Grip1	glutamate receptor interacting protein 1	0.222
Grxcr1	glutaredoxin, cysteine rich 1	0.220
Dync1i2	dynein cytoplasmic 1 intermediate chain 2	0.220
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.219
Cdh5	cadherin 5	0.219
Fzd1	frizzled homolog 1 (Drosophila)	0.216
Mapkap1	mitogen-activated protein kinase associated protein 1	0.216
Plcg1	phospholipase C, gamma 1	0.216
Plcg2	phospholipase C, gamma 2	0.214
Bmp2	bone morphogenetic protein 2	0.211
Gli2	GLI-Kruppel family member GLI2	0.210
Pgr	progesterone receptor	0.209
Flii	flightless I homolog (Drosophila)	0.207	Mouse
Fes	feline sarcoma oncogene	0.206	Human
Acvr2a	activin receptor IIA	0.206
Gdf11	growth differentiation factor 11	0.205
Unc5c	unc-5 homolog C (C. elegans)	0.205	Worm
Tgfbr2	transforming growth factor, beta receptor II	0.203	Mouse
Twist2	twist homolog 2 (Drosophila)	0.203
Smad7	MAD homolog 7 (Drosophila)	0.202
Ndn	necdin	0.202
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.200
S1pr3	sphingosine-1-phosphate receptor 3	0.198	Mouse
Axin1	axin 1	0.197
Mtap2	microtubule-associated protein 2	0.196	Mouse
Cttn	cortactin	0.196
Actb	actin, beta	0.195
Sh3bgrl3	SH3 domain binding glutamic acid-rich protein-like 3	0.194
Epha4	Eph receptor A4	0.189
Vangl1	vang-like 1 (van gogh, Drosophila)	0.188
Jag2	jagged 2	0.188
Spna2	spectrin alpha 2	0.187
Ntm	neurotrimin	0.186	Mouse
Apbb1	amyloid beta (A4) precursor protein-binding, family B, member 1	0.186
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.185
Dlg4	discs, large homolog 4 (Drosophila)	0.185
Ctdnep1	CTD nuclear envelope phosphatase 1	0.183
Xiap	X-linked inhibitor of apoptosis	0.183
Ncor2	nuclear receptor co-repressor 2	0.182
Epha3	Eph receptor A3	0.180	Human
Mef2d	myocyte enhancer factor 2D	0.177
Robo2	roundabout homolog 2 (Drosophila)	0.174	Human
Shd	src homology 2 domain-containing transforming protein D	0.174
Tgfb2	transforming growth factor, beta 2	0.172
Bbs2	Bardet-Biedl syndrome 2 (human)	0.171
Aff2	AF4/FMR2 family, member 2	0.168
Ntn1	netrin 1	0.166
Grb2	growth factor receptor bound protein 2	0.164
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.164
Arvcf	armadillo repeat gene deleted in velo-cardio-facial syndrome	0.163
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.163
Nrg1	neuregulin 1	0.162
Rab5a	RAB5A, member RAS oncogene family	0.162
Mobkl3	MOB1, Mps One Binder kinase activator-like 3 (yeast)	0.161
App	amyloid beta (A4) precursor protein	0.161
Kcnma1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	0.160
Sox5	SRY-box containing gene 5	0.159
Dkk3	dickkopf homolog 3 (Xenopus laevis)	0.158
Spock1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1	0.157
Gap43	growth associated protein 43	0.156
Armcx3	armadillo repeat containing, X-linked 3	0.154	Mouse
En1	engrailed 1	0.153
Grm1	glutamate receptor, metabotropic 1	0.153
Ednra	endothelin receptor type A	0.152
Smurf2	SMAD specific E3 ubiquitin protein ligase 2	0.150
Neo1	neogenin	0.150
Mb	myoglobin	0.149
Ikzf1	IKAROS family zinc finger 1	0.146
Nrcam	neuron-glia-CAM-related cell adhesion molecule	0.146
Armcx2	armadillo repeat containing, X-linked 2	0.145	Mouse
Drap1	Dr1 associated protein 1 (negative cofactor 2 alpha)	0.145
Nos1	nitric oxide synthase 1, neuronal	0.145
Fgf15	fibroblast growth factor 15	0.145
Apba2	amyloid beta (A4) precursor protein-binding, family A, member 2	0.144
Fzd8	frizzled homolog 8 (Drosophila)	0.143
Foxq1	forkhead box Q1	0.143
Kcnd3	potassium voltage-gated channel, Shal-related family, member 3	0.142
Agrn	agrin	0.142	Rat
Gab1	growth factor receptor bound protein 2-associated protein 1	0.142
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.140	Mouse
Ptprs	protein tyrosine phosphatase, receptor type, S	0.138	Mouse
Pkd2	polycystic kidney disease 2	0.138
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.138
Cit	citron	0.137
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.137
Srrm4	serine/arginine repetitive matrix 4	0.137
Rnf208	ring finger protein 208	0.136
Cpeb3	cytoplasmic polyadenylation element binding protein 3	0.136
Chl1	cell adhesion molecule with homology to L1CAM	0.135
Sec23a	SEC23A (S. cerevisiae)	0.135
Prl3b1	prolactin family 3, subfamily b, member 1	0.134	Mouse
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.134
Mmp15	matrix metallopeptidase 15	0.134
Vcl	vinculin	0.133
Ptprd	protein tyrosine phosphatase, receptor type, D	0.133
Shc3	src homology 2 domain-containing transforming protein C3	0.133
Krt1	keratin 1	0.132
Homer1	homer homolog 1 (Drosophila)	0.130
Gpr153	G protein-coupled receptor 153	0.130
Lama5	laminin, alpha 5	0.130
Cdh4	cadherin 4	0.130
Gucy1b3	guanylate cyclase 1, soluble, beta 3	0.129
Sept9	septin 9	0.129
Col12a1	collagen, type XII, alpha 1	0.129
Prkar1b	protein kinase, cAMP dependent regulatory, type I beta	0.129
Gpr98	G protein-coupled receptor 98	0.128
Sez6	seizure related gene 6	0.127
Parva	parvin, alpha	0.127
Rgs4	regulator of G-protein signaling 4	0.126
Prkcb	protein kinase C, beta	0.126
Cd68	CD68 antigen	0.126
Notch3	Notch gene homolog 3 (Drosophila)	0.124
Lilrb3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.124
Cx3cr1	chemokine (C-X3-C) receptor 1	0.123
Irs1	insulin receptor substrate 1	0.123
Cd40	CD40 antigen	0.122
Capn6	calpain 6	0.122
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.122
Cacng2	calcium channel, voltage-dependent, gamma subunit 2	0.120
Aplp2	amyloid beta (A4) precursor-like protein 2	0.120
Samd4	sterile alpha motif domain containing 4	0.120
Rnpepl1	arginyl aminopeptidase (aminopeptidase B)-like 1	0.119
Accn1	amiloride-sensitive cation channel 1, neuronal (degenerin)	0.119
Wwtr1	WW domain containing transcription regulator 1	0.119
Adra2a	adrenergic receptor, alpha 2a	0.119
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.118
Cpeb4	cytoplasmic polyadenylation element binding protein 4	0.118	Mouse
Fgf5	fibroblast growth factor 5	0.117
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.117
Nphs2	nephrosis 2 homolog, podocin (human)	0.117
Dscaml1	Down syndrome cell adhesion molecule-like 1	0.117	Mouse
Chordc1	cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1	0.117
Pfn2	profilin 2	0.116
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.116
Eln	elastin	0.115
Vgf	VGF nerve growth factor inducible	0.115
Evl	Ena-vasodilator stimulated phosphoprotein	0.114	Fly
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.114
P2ry2	purinergic receptor P2Y, G-protein coupled 2	0.114
Adamtsl5	ADAMTS-like 5	0.113
Rac2	RAS-related C3 botulinum substrate 2	0.113
Zic4	zinc finger protein of the cerebellum 4	0.113
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.112
Fgf2	fibroblast growth factor 2	0.112
Mdfi	MyoD family inhibitor	0.112
Rap1b	RAS related protein 1b	0.112	Mouse
Prl3d1	prolactin family 3, subfamily d, member 1	0.111	Mouse
Sparcl1	SPARC-like 1	0.111
Tubb4	tubulin, beta 4	0.111
Mpdz	multiple PDZ domain protein	0.111
Il1r1	interleukin 1 receptor, type I	0.110
Notch2	Notch gene homolog 2 (Drosophila)	0.110
Pecam1	platelet/endothelial cell adhesion molecule 1	0.109
Flt3	FMS-like tyrosine kinase 3	0.109
Dlgap4	discs, large homolog-associated protein 4 (Drosophila)	0.108
Ahi1	Abelson helper integration site 1	0.108
Kcnd1	potassium voltage-gated channel, Shal-related family, member 1	0.108
Cacna1g	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.108
Nppc	natriuretic peptide type C	0.108
Cdc42se1	CDC42 small effector 1	0.106
Calb2	calbindin 2	0.106
Cd28	CD28 antigen	0.106
Stx12	syntaxin 12	0.106
Rptor	regulatory associated protein of MTOR, complex 1	0.105
Acvrl1	activin A receptor, type II-like 1	0.105	Mouse
Mtch1	mitochondrial carrier homolog 1 (C. elegans)	0.105
Flot1	flotillin 1	0.104
Rgnef	Rho-guanine nucleotide exchange factor	0.103
Cldn16	claudin 16	0.103
Tnfrsf19	tumor necrosis factor receptor superfamily, member 19	0.103
Serinc1	serine incorporator 1	0.103
Zfp651	zinc finger protein 651	0.103
Pou3f2	POU domain, class 3, transcription factor 2	0.102
Nkd1	naked cuticle 1 homolog (Drosophila)	0.102
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.101
Phox2a	paired-like homeobox 2a	0.101
Myh10	myosin, heavy polypeptide 10, non-muscle	0.101
Kdr	kinase insert domain protein receptor	0.101
Map2k2	mitogen-activated protein kinase kinase 2	0.100
Pdcd10	programmed cell death 10	0.100
Slc12a4	solute carrier family 12, member 4	0.100
Tacr3	tachykinin receptor 3	0.100
Lmna	lamin A	0.100
Skil	SKI-like	0.099	Human
Ric8	resistance to inhibitors of cholinesterase 8 homolog (C. elegans)	0.099
Mmp12	matrix metallopeptidase 12	0.098
Odz3	odd Oz/ten-m homolog 3 (Drosophila)	0.098
Sept7	septin 7	0.097
Dsg2	desmoglein 2	0.096
Camk2b	calcium/calmodulin-dependent protein kinase II, beta	0.096	Rat
Abl2	v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)	0.096
Hs3st3a1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	0.096
Sdc3	syndecan 3	0.095
Cdh22	cadherin 22	0.095
Pdgfa	platelet derived growth factor, alpha	0.095	Mouse
Ube3b	ubiquitin protein ligase E3B	0.095
Ptprn	protein tyrosine phosphatase, receptor type, N	0.094
Cdk5r2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.094
Prl7a1	prolactin family 7, subfamily a, member 1	0.094	Mouse
Plxna4	plexin A4	0.094	Mouse
Nbea	neurobeachin	0.094
Adra2b	adrenergic receptor, alpha 2b	0.094
Gfpt2	glutamine fructose-6-phosphate transaminase 2	0.093
Hcls1	hematopoietic cell specific Lyn substrate 1	0.093
Zfhx4	zinc finger homeodomain 4	0.093
St8sia1	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1	0.092
Smpd3	sphingomyelin phosphodiesterase 3, neutral	0.092
Bhlhe22	basic helix-loop-helix family, member e22	0.092
Gip	gastric inhibitory polypeptide	0.092
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.092
Cacnb1	calcium channel, voltage-dependent, beta 1 subunit	0.091
Gja10	gap junction protein, alpha 10	0.091
Ncf1	neutrophil cytosolic factor 1	0.091
Ncdn	neurochondrin	0.091
Kcnn3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3	0.090
Wnt3	wingless-related MMTV integration site 3	0.090
Dctn1	dynactin 1	0.090
Efna5	ephrin A5	0.090
Pik3c2a	phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide	0.089
Npr2	natriuretic peptide receptor 2	0.089
Hgf	hepatocyte growth factor	0.089	Rat
Cxcl14	chemokine (C-X-C motif) ligand 14	0.089
Vegfa	vascular endothelial growth factor A	0.089
Tesk1	testis specific protein kinase 1	0.088	Mouse
Fgf18	fibroblast growth factor 18	0.088
Epb4.1l1	erythrocyte protein band 4.1-like 1	0.088
Cxcl2	chemokine (C-X-C motif) ligand 2	0.088
Aire	autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)	0.088
Dbnl	drebrin-like	0.087
Dvl3	dishevelled 3, dsh homolog (Drosophila)	0.087	Mouse
Csnk1g2	casein kinase 1, gamma 2	0.086
Fosl2	fos-like antigen 2	0.086
Cabp2	calcium binding protein 2	0.085
Eno2	enolase 2, gamma neuronal	0.085
Il6	interleukin 6	0.085
Dlg2	discs, large homolog 2 (Drosophila)	0.085
Ctnnd2	catenin (cadherin associated protein), delta 2	0.085
Matn4	matrilin 4	0.084
Ppp1cb	protein phosphatase 1, catalytic subunit, beta isoform	0.084
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.084
Ivl	involucrin	0.084
Ncam1	neural cell adhesion molecule 1	0.084
Dag1	dystroglycan 1	0.084
Kcnj10	potassium inwardly-rectifying channel, subfamily J, member 10	0.084
Atp2c1	ATPase, Ca++-sequestering	0.084
Mgat3	mannoside acetylglucosaminyltransferase 3	0.084
Emx1	empty spiracles homolog 1 (Drosophila)	0.083
Lama4	laminin, alpha 4	0.082
P2rx6	purinergic receptor P2X, ligand-gated ion channel, 6	0.082
Ptprk	protein tyrosine phosphatase, receptor type, K	0.082	Mouse
Sirpa	signal-regulatory protein alpha	0.081
Ets1	E26 avian leukemia oncogene 1, 5' domain	0.081
Yap1	yes-associated protein 1	0.081
Rab1	RAB1, member RAS oncogene family	0.081	Fly
Sez6l	seizure related 6 homolog like	0.081	Mouse
Cntn1	contactin 1	0.080
Kl	klotho	0.080
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.080
Gnai3	guanine nucleotide binding protein (G protein), alpha inhibiting 3	0.080
Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like	0.080
Epb4.1l2	erythrocyte protein band 4.1-like 2	0.079
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.079
Phldb1	pleckstrin homology-like domain, family B, member 1	0.079
Tjp1	tight junction protein 1	0.079
Asap1	ArfGAP with SH# domain, ankyrin repeat and PH domain1	0.078
Rps6ka4	ribosomal protein S6 kinase, polypeptide 4	0.078
Sept3	septin 3	0.078
Il2rb	interleukin 2 receptor, beta chain	0.078
Ctnna1	catenin (cadherin associated protein), alpha 1	0.077
Extl3	exostoses (multiple)-like 3	0.077
Mark1	MAP/microtubule affinity-regulating kinase 1	0.077
Prrx2	paired related homeobox 2	0.077
Padi2	peptidyl arginine deiminase, type II	0.077
Npas3	neuronal PAS domain protein 3	0.077
Sele	selectin, endothelial cell	0.077
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.076	Mouse
Ache	acetylcholinesterase	0.076
Srebf2	sterol regulatory element binding factor 2	0.076
Ralgds	ral guanine nucleotide dissociation stimulator	0.076
Adcy1	adenylate cyclase 1	0.075
Ptpn12	protein tyrosine phosphatase, non-receptor type 12	0.075
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.075
Mllt1	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1	0.075
Slit1	slit homolog 1 (Drosophila)	0.075	Zebrafish
Stmn4	stathmin-like 4	0.075
Smad4	MAD homolog 4 (Drosophila)	0.075
Apbb1ip	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	0.075
Ccl8	chemokine (C-C motif) ligand 8	0.075
Col22a1	collagen, type XXII, alpha 1	0.075
Epn2	epsin 2	0.075
Mkl1	MKL (megakaryoblastic leukemia)/myocardin-like 1	0.074
Dsg1a	desmoglein 1 alpha	0.074
Agtr2	angiotensin II receptor, type 2	0.074
Akap12	A kinase (PRKA) anchor protein (gravin) 12	0.074
Tspan9	tetraspanin 9	0.074
Spin1	spindlin 1	0.074
Fjx1	four jointed box 1 (Drosophila)	0.074
Sema3c	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	0.073
Ccl7	chemokine (C-C motif) ligand 7	0.073	Mouse
Sez6l2	seizure related 6 homolog like 2	0.073	Mouse
Sox18	SRY-box containing gene 18	0.073
Prl7d1	prolactin family 7, subfamily d, member 1	0.073	Mouse
Ptprg	protein tyrosine phosphatase, receptor type, G	0.072
Ceacam11	carcinoembryonic antigen-related cell adhesion molecule 11	0.072
Sorbs1	sorbin and SH3 domain containing 1	0.072
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.072
Mtpn	myotrophin	0.071
Cdh1	cadherin 1	0.071	Mouse
Il13ra2	interleukin 13 receptor, alpha 2	0.071
St6galnac3	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3	0.071
Dpysl2	dihydropyrimidinase-like 2	0.071
Fzd2	frizzled homolog 2 (Drosophila)	0.071
Tmprss2	transmembrane protease, serine 2	0.071
Grik4	glutamate receptor, ionotropic, kainate 4	0.071
Bag6	BCL2-associated athanogene 6	0.071
Pls3	plastin 3 (T-isoform)	0.070
Prl2b1	prolactin family 2, subfamily b, member 1	0.070	Mouse
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.070
Plxna3	plexin A3	0.070	Mouse
Elavl4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)	0.070	Rat
Masp1	mannan-binding lectin serine peptidase 1	0.069
Lmx1b	LIM homeobox transcription factor 1 beta	0.069
Armcx1	armadillo repeat containing, X-linked 1	0.069	Mouse
Il10ra	interleukin 10 receptor, alpha	0.069
B3galt1	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1	0.069
Ptprc	protein tyrosine phosphatase, receptor type, C	0.069
Gas1	growth arrest specific 1	0.069
Fndc3b	fibronectin type III domain containing 3B	0.069
Wwc1	WW, C2 and coiled-coil domain containing 1	0.069
Ctnnd1	catenin (cadherin associated protein), delta 1	0.069
Hbegf	heparin-binding EGF-like growth factor	0.068
Scn3a	sodium channel, voltage-gated, type III, alpha	0.068
Invs	inversin	0.068
Vapa	vesicle-associated membrane protein, associated protein A	0.068
Tmc1	transmembrane channel-like gene family 1	0.068
Obsl1	obscurin-like 1	0.068
Asxl3	additional sex combs like 3 (Drosophila)	0.067
Adam17	a disintegrin and metallopeptidase domain 17	0.067
Phldb2	pleckstrin homology-like domain, family B, member 2	0.067
Rhog	ras homolog gene family, member G	0.067	Mouse
Ldb2	LIM domain binding 2	0.067
Lrrtm1	leucine rich repeat transmembrane neuronal 1	0.067
Tmeff2	transmembrane protein with EGF-like and two follistatin-like domains 2	0.067
Prl3c1	prolactin family 3, subfamily c, member 1	0.067	Mouse
Numbl	numb-like	0.067	Rat
Stat6	signal transducer and activator of transcription 6	0.067
Limk1	LIM-domain containing, protein kinase	0.066
Zyx	zyxin	0.066
Ski	ski sarcoma viral oncogene homolog (avian)	0.066
Itgb4	integrin beta 4	0.066
Fut9	fucosyltransferase 9	0.066
Hck	hemopoietic cell kinase	0.066	Mouse
Sox11	SRY-box containing gene 11	0.065
Esr1	estrogen receptor 1 (alpha)	0.065
Cd247	CD247 antigen	0.065
Msi1	Musashi homolog 1(Drosophila)	0.065
Fcgr1	Fc receptor, IgG, high affinity I	0.065
Agap1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	0.065
Lhx1	LIM homeobox protein 1	0.065
Ptprj	protein tyrosine phosphatase, receptor type, J	0.065
Ccm2	cerebral cavernous malformation 2 homolog (human)	0.064
Has1	hyaluronan synthase1	0.064
Ddr2	discoidin domain receptor family, member 2	0.064
Sema5a	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.064
Ptprb	protein tyrosine phosphatase, receptor type, B	0.064
Gal	galanin	0.064
Cpz	carboxypeptidase Z	0.064
Fgf8	fibroblast growth factor 8	0.063
Lox	lysyl oxidase	0.063
Rap2c	RAP2C, member of RAS oncogene family	0.063	Mouse
D630037F22Rik	RIKEN cDNA D630037F22 gene	0.063
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.063	Mouse
Cbl	Casitas B-lineage lymphoma	0.063
Zap70	zeta-chain (TCR) associated protein kinase	0.063
Crabp2	cellular retinoic acid binding protein II	0.062
Rtn4r	reticulon 4 receptor	0.062
Trpv2	transient receptor potential cation channel, subfamily V, member 2	0.062
Cdc42bpb	CDC42 binding protein kinase beta	0.062
Arl4c	ADP-ribosylation factor-like 4C	0.062
Bbs1	Bardet-Biedl syndrome 1 (human)	0.062
Zmiz2	zinc finger, MIZ-type containing 2	0.062
Shank3	SH3/ankyrin domain gene 3	0.061
Dll4	delta-like 4 (Drosophila)	0.061
Smad2	MAD homolog 2 (Drosophila)	0.061
Slc1a6	solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6	0.061
Sema4g	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G	0.061	Mouse
Flt4	FMS-like tyrosine kinase 4	0.061
Cryab	crystallin, alpha B	0.061
Epn1	epsin 1	0.061
Isl1	ISL1 transcription factor, LIM/homeodomain	0.060
Ebi3	Epstein-Barr virus induced gene 3	0.060
Numb	numb gene homolog (Drosophila)	0.060
Rac1	RAS-related C3 botulinum substrate 1	0.060	Human Mouse Fly
Zfp532	zinc finger protein 532	0.059
Arhgap9	Rho GTPase activating protein 9	0.059
Emp2	epithelial membrane protein 2	0.059
Lsp1	lymphocyte specific 1	0.059
Rasl10a	RAS-like, family 10, member A	0.059
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.059
Magi1	membrane associated guanylate kinase, WW and PDZ domain containing 1	0.059
Tpm4	tropomyosin 4	0.059
Actr3	ARP3 actin-related protein 3 homolog (yeast)	0.059	Rat Fly
Epha2	Eph receptor A2	0.059
Mpzl2	myelin protein zero-like 2	0.059
Myo1c	myosin IC	0.059
Hif1a	hypoxia inducible factor 1, alpha subunit	0.058
Trp73	transformation related protein 73	0.058
Tcfap2b	transcription factor AP-2 beta	0.058
Cdh15	cadherin 15	0.058	Mouse
Ch25h	cholesterol 25-hydroxylase	0.058
Ntf5	neurotrophin 5	0.058	Mouse
Nhlh1	nescient helix loop helix 1	0.058
Fermt2	fermitin family homolog 2 (Drosophila)	0.058
Gak	cyclin G associated kinase	0.058
Epb4.9	erythrocyte protein band 4.9	0.058
Rnf11	ring finger protein 11	0.058
Adora3	adenosine A3 receptor	0.058
Zim1	zinc finger, imprinted 1	0.057
Kif1b	kinesin family member 1B	0.057
Celf3	VCUGBP, Elav-like family member 3	0.057
Foxk1	forkhead box K1	0.057
Akt3	thymoma viral proto-oncogene 3	0.057	Fly
Odz4	odd Oz/ten-m homolog 4 (Drosophila)	0.057	Mouse
Galntl1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1	0.057
Adcy8	adenylate cyclase 8	0.057
Pvrl3	poliovirus receptor-related 3	0.057
Rhox9	reproductive homeobox 9	0.057
Gja1	gap junction protein, alpha 1	0.057
Rhox6	reproductive homeobox 6	0.057
Ptov1	prostate tumor over expressed gene 1	0.057
Epn3	epsin 3	0.057
Mtap4	microtubule-associated protein 4	0.057	Mouse
Gab2	growth factor receptor bound protein 2-associated protein 2	0.057
Plcb1	phospholipase C, beta 1	0.057
Wnk2	WNK lysine deficient protein kinase 2	0.057
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.057
Stx4a	syntaxin 4A (placental)	0.057
Kalrn	kalirin, RhoGEF kinase	0.056	Worm
Neto1	neuropilin (NRP) and tolloid (TLL)-like 1	0.056
Plxna2	plexin A2	0.056	Mouse
Pax3	paired box gene 3	0.056
Arpc4	actin related protein 2/3 complex, subunit 4	0.056
Nfe2l3	nuclear factor, erythroid derived 2, like 3	0.056
Atp9a	ATPase, class II, type 9A	0.056
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.056
Batf	basic leucine zipper transcription factor, ATF-like	0.056
Zfp423	zinc finger protein 423	0.056
Ltbp1	latent transforming growth factor beta binding protein 1	0.055
Timp3	tissue inhibitor of metalloproteinase 3	0.055
F3	coagulation factor III	0.055
Baiap2	brain-specific angiogenesis inhibitor 1-associated protein 2	0.055
Nynrin	NYN domain and retroviral integrase containing	0.055
Rgma	RGM domain family, member A	0.055
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.055
Galnt6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6	0.055
Kcnq4	potassium voltage-gated channel, subfamily Q, member 4	0.055
Epha7	Eph receptor A7	0.055
Dusp16	dual specificity phosphatase 16	0.055
Wdr86	WD repeat domain 86	0.055
Hivep2	human immunodeficiency virus type I enhancer binding protein 2	0.055
Smtnl2	smoothelin-like 2	0.055
Camk2d	calcium/calmodulin-dependent protein kinase II, delta	0.055
Arid1a	AT rich interactive domain 1A (SWI-like)	0.055
Cdh6	cadherin 6	0.054
Adora2b	adenosine A2b receptor	0.054
Pou3f1	POU domain, class 3, transcription factor 1	0.054
Cygb	cytoglobin	0.054
Tgfbr3	transforming growth factor, beta receptor III	0.054
Rap2b	RAP2B, member of RAS oncogene family	0.054	Mouse
Clstn1	calsyntenin 1	0.054
Acvr2b	activin receptor IIB	0.054
Ier5l	immediate early response 5-like	0.054
Gm14548	predicted gene 14548	0.054
Gnb4	guanine nucleotide binding protein (G protein), beta 4	0.054
Fgfr3	fibroblast growth factor receptor 3	0.054	Mouse
Tgfa	transforming growth factor alpha	0.054
Hdac5	histone deacetylase 5	0.054
Il1rn	interleukin 1 receptor antagonist	0.053
Rbms3	RNA binding motif, single stranded interacting protein	0.053
Tbx2	T-box 2	0.053
Lama1	laminin, alpha 1	0.053
Prl2a1	prolactin family 2, subfamily a, member 1	0.053	Mouse
Fgf9	fibroblast growth factor 9	0.053
Gtf3c1	general transcription factor III C 1	0.053
Ptpre	protein tyrosine phosphatase, receptor type, E	0.053
Fam83h	family with sequence similarity 83, member H	0.053
Large	like-glycosyltransferase	0.053
Cnih2	cornichon homolog 2 (Drosophila)	0.052
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.052
Axin2	axin2	0.052
Cdk14	cyclin-dependent kinase 14	0.052
Ifng	interferon gamma	0.052
Mapkapk2	MAP kinase-activated protein kinase 2	0.052
Emilin3	elastin microfibril interfacer 3	0.052
Nudt11	nudix (nucleoside diphosphate linked moiety X)-type motif 11	0.052
Csf3	colony stimulating factor 3 (granulocyte)	0.052
Rgs14	regulator of G-protein signaling 14	0.052
Was	Wiskott-Aldrich syndrome homolog (human)	0.052
Plekhh1	pleckstrin homology domain containing, family H (with MyTH4 domain) member 1	0.052
Irx2	Iroquois related homeobox 2 (Drosophila)	0.051
Dnajb9	DnaJ (Hsp40) homolog, subfamily B, member 9	0.051
Selplg	selectin, platelet (p-selectin) ligand	0.051
Sdcbp	syndecan binding protein	0.051
Gm2012	predicted gene 2012	0.051
Map4k3	mitogen-activated protein kinase kinase kinase kinase 3	0.051
Crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.051
Csnk1a1	casein kinase 1, alpha 1	0.051
Pcdh12	protocadherin 12	0.051
Atp1b1	ATPase, Na+/K+ transporting, beta 1 polypeptide	0.051
Nkg7	natural killer cell group 7 sequence	0.051
Ephb6	Eph receptor B6	0.051
Sla	src-like adaptor	0.050
Ncam2	neural cell adhesion molecule 2	0.050
Lrp1	low density lipoprotein receptor-related protein 1	0.050
Gabrb3	gamma-aminobutyric acid (GABA) A receptor, subunit beta 3	0.050
Tbkbp1	TBK1 binding protein 1	0.050
Plin3	perilipin 3	0.050
Mtap1b	microtubule-associated protein 1B	0.050
Aldh1a3	aldehyde dehydrogenase family 1, subfamily A3	0.050
Slco6c1	solute carrier organic anion transporter family, member 6c1	0.050
Flnc	filamin C, gamma	0.050
Nrp2	neuropilin 2	0.050	Mouse
Krt25	keratin 25	0.050
Myo1f	myosin IF	0.050
Rasl11b	RAS-like, family 11, member B	0.050
Vps52	vacuolar protein sorting 52 (yeast)	0.050
Rnd3	Rho family GTPase 3	0.050	Mouse
Utrn	utrophin	0.050
Maged2	melanoma antigen, family D, 2	0.050
Elavl2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)	0.050
Ptprm	protein tyrosine phosphatase, receptor type, M	0.050	Mouse
8430410K20Rik	RIKEN cDNA 8430410K20 gene	0.049
Cyfip2	cytoplasmic FMR1 interacting protein 2	0.049
Lcp1	lymphocyte cytosolic protein 1	0.049
Cldn5	claudin 5	0.049
Nrg3	neuregulin 3	0.049
Syt17	synaptotagmin XVII	0.049
Neurog2	neurogenin 2	0.049
Clnk	cytokine-dependent hematopoietic cell linker	0.049
Ctsw	cathepsin W	0.049
Hoxc6	homeobox C6	0.049
Cxcr4	chemokine (C-X-C motif) receptor 4	0.049
Pex5l	peroxisomal biogenesis factor 5-like	0.049
Esr2	estrogen receptor 2 (beta)	0.049
Dync2h1	dynein cytoplasmic 2 heavy chain 1	0.049
Dpp6	dipeptidylpeptidase 6	0.049
Gsk3a	glycogen synthase kinase 3 alpha	0.049	Mouse
Sphk1	sphingosine kinase 1	0.049	Rat
Atxn7l3	ataxin 7-like 3	0.049
Pde3a	phosphodiesterase 3A, cGMP inhibited	0.049
Sorcs3	sortilin-related VPS10 domain containing receptor 3	0.048
Cx3cl1	chemokine (C-X3-C motif) ligand 1	0.048
Gjd2	gap junction protein, delta 2	0.048
Itpkb	inositol 1,4,5-trisphosphate 3-kinase B	0.048
Prnd	prion protein dublet	0.048
Adam9	a disintegrin and metallopeptidase domain 9 (meltrin gamma)	0.048
Cbfb	core binding factor beta	0.048
Rab10	RAB10, member RAS oncogene family	0.048
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.048
Tmem151b	transmembrane protein 151B	0.048
Ebf4	early B-cell factor 4	0.048
Msr1	macrophage scavenger receptor 1	0.048
Zfp518b	zinc finger protein 518B	0.048
Caskin1	CASK interacting protein 1	0.048
Elavl3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	0.048
Ctnna2	catenin (cadherin associated protein), alpha 2	0.048
Tax1bp3	Tax1 (human T-cell leukemia virus type I) binding protein 3	0.048
Anapc2	anaphase promoting complex subunit 2	0.048
Gpc6	glypican 6	0.048
Lrp6	low density lipoprotein receptor-related protein 6	0.047
Sfrp1	secreted frizzled-related protein 1	0.047
Mmp2	matrix metallopeptidase 2	0.047
Mc1r	melanocortin 1 receptor	0.047
Wwc2	WW, C2 and coiled-coil domain containing 2	0.047
Adcy7	adenylate cyclase 7	0.047
Itgb3	integrin beta 3	0.047
Myt1	myelin transcription factor 1	0.047
Col4a6	collagen, type IV, alpha 6	0.047
Porcn	porcupine homolog (Drosophila)	0.047
Phactr1	phosphatase and actin regulator 1	0.047
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.047
Chmp1b	chromatin modifying protein 1B	0.047
Rap2a	RAS related protein 2a	0.047	Mouse
Acsl4	acyl-CoA synthetase long-chain family member 4	0.047
Raf1	v-raf-leukemia viral oncogene 1	0.047
Klc2	kinesin light chain 2	0.047
Cd3e	CD3 antigen, epsilon polypeptide	0.047
Lhx9	LIM homeobox protein 9	0.047
Clip2	CAP-GLY domain containing linker protein 2	0.047
Bcr	breakpoint cluster region	0.047
Rala	v-ral simian leukemia viral oncogene homolog A (ras related)	0.046	Human
Zxdb	zinc finger, X-linked, duplicated B	0.046
Apbb2	amyloid beta (A4) precursor protein-binding, family B, member 2	0.046
Kif1a	kinesin family member 1A	0.046
Aebp1	AE binding protein 1	0.046
Dnajb5	DnaJ (Hsp40) homolog, subfamily B, member 5	0.046
Cbln1	cerebellin 1 precursor protein	0.046
Kcnh1	potassium voltage-gated channel, subfamily H (eag-related), member 1	0.046
Scd1	stearoyl-Coenzyme A desaturase 1	0.046
Camsap1	calmodulin regulated spectrin-associated protein 1	0.046
Matn1	matrilin 1, cartilage matrix protein	0.046
Arhgef1	Rho guanine nucleotide exchange factor (GEF) 1	0.046
Egfr	epidermal growth factor receptor	0.046
Bmp5	bone morphogenetic protein 5	0.046	Human
Calm1	calmodulin 1	0.046
Kif3a	kinesin family member 3A	0.046
Nav3	neuron navigator 3	0.046
Efna3	ephrin A3	0.046
Ntng1	netrin G1	0.046
Tnfrsf8	tumor necrosis factor receptor superfamily, member 8	0.046
Dclk1	doublecortin-like kinase 1	0.046
Zfr2	zinc finger RNA binding protein 2	0.046
Arf2	ADP-ribosylation factor 2	0.046
Zic3	zinc finger protein of the cerebellum 3	0.045
Slc6a9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	0.045
Prss8	protease, serine, 8 (prostasin)	0.045
Trhr	thyrotropin releasing hormone receptor	0.045
Dchs1	dachsous 1 (Drosophila)	0.045
Ghrh	growth hormone releasing hormone	0.045
Mfi2	antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5	0.045
Grin2d	glutamate receptor, ionotropic, NMDA2D (epsilon 4)	0.045
Angpt1	angiopoietin 1	0.045
Cadps	Ca2+-dependent secretion activator	0.045
Acan	aggrecan	0.045
Pkn2	protein kinase N2	0.045
Fgfr4	fibroblast growth factor receptor 4	0.045	Mouse
Cyth4	cytohesin 4	0.045
Chst2	carbohydrate sulfotransferase 2	0.045
Enc1	ectodermal-neural cortex 1	0.045	Rat
Endou	endonuclease, polyU-specific	0.045
Tert	telomerase reverse transcriptase	0.045
Arc	activity regulated cytoskeletal-associated protein	0.045
Ltb	lymphotoxin B	0.045
Cd22	CD22 antigen	0.045
Nxph1	neurexophilin 1	0.045
Tulp1	tubby like protein 1	0.044
Nsg1	neuron specific gene family member 1	0.044
Lcp2	lymphocyte cytosolic protein 2	0.044
Dbc1	deleted in bladder cancer 1 (human)	0.044
Tek	endothelial-specific receptor tyrosine kinase	0.044
Ppt1	palmitoyl-protein thioesterase 1	0.044
Tbxas1	thromboxane A synthase 1, platelet	0.044
Wnt9a	wingless-type MMTV integration site 9A	0.044	Mouse
2810008M24Rik	RIKEN cDNA 2810008M24 gene	0.044
Bmper	BMP-binding endothelial regulator	0.044
Tnni2	troponin I, skeletal, fast 2	0.044
Peg3	paternally expressed 3	0.044
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.044