IMP: Integrative Multi-species Prediction

Mus musculus

47 genes annotated in mouse

positive regulation of erk1 and erk2 cascade

Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of erk1 and erk2 cascade"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "positive regulation of erk1 and erk2 cascade" (in gray)

Name	Description	Probability	Func Analog Organism
Cd44	CD44 antigen	0.993
Lepr	leptin receptor	0.955
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.919	Human Mouse
Pten	phosphatase and tensin homolog	0.896
Shh	sonic hedgehog	0.890
Lyz2	lysozyme 2	0.877
Cbl	Casitas B-lineage lymphoma	0.875
Cav1	caveolin 1, caveolae protein	0.871
Vegfa	vascular endothelial growth factor A	0.869
Acvr1	activin A receptor, type 1	0.865
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.864
Csf1	colony stimulating factor 1 (macrophage)	0.845
Egfr	epidermal growth factor receptor	0.830
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.758
Ptk2	PTK2 protein tyrosine kinase 2	0.751
Ccl2	chemokine (C-C motif) ligand 2	0.745
Plcg1	phospholipase C, gamma 1	0.736
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.732
Prkce	protein kinase C, epsilon	0.694
Grb2	growth factor receptor bound protein 2	0.684
Kl	klotho	0.676
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.661
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.639
Ghr	growth hormone receptor	0.625
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.612	Human
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.606
Fgf10	fibroblast growth factor 10	0.604
Mmp9	matrix metallopeptidase 9	0.583
Bdnf	brain derived neurotrophic factor	0.558
Tgfbr2	transforming growth factor, beta receptor II	0.530
C1qa	complement component 1, q subcomponent, alpha polypeptide	0.527
H2-Aa	histocompatibility 2, class II antigen A, alpha	0.523
Nrp1	neuropilin 1	0.487
Tcf21	transcription factor 21	0.480
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.468
Kdr	kinase insert domain protein receptor	0.458	Human Mouse
Chrd	chordin	0.457
Ednra	endothelin receptor type A	0.452	Rat
Lmna	lamin A	0.449
Fyn	Fyn proto-oncogene	0.439	Mouse
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.438
Raf1	v-raf-leukemia viral oncogene 1	0.433	Mouse Fly
Ywhae	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.430	Fly
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.430	Fly
Ccr1	chemokine (C-C motif) receptor 1	0.411	Human
Casp1	caspase 1	0.401
Hoxa1	homeobox A1	0.394
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.390
Tlr2	toll-like receptor 2	0.380	Mouse
Cd86	CD86 antigen	0.380
Arrb1	arrestin, beta 1	0.374
Cx3cr1	chemokine (C-X3-C) receptor 1	0.371
Dok1	docking protein 1	0.367
Arrb2	arrestin, beta 2	0.360	Human Mouse
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.358
Bmp4	bone morphogenetic protein 4	0.352
Ccr2	chemokine (C-C motif) receptor 2	0.350
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.349
Inpp5d	inositol polyphosphate-5-phosphatase D	0.348
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.338	Fly
Fcgr1	Fc receptor, IgG, high affinity I	0.330
H2-Eb1	histocompatibility 2, class II antigen E beta	0.328
Rdh8	retinol dehydrogenase 8	0.327
Pthlh	parathyroid hormone-like peptide	0.320
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.315
Btk	Bruton agammaglobulinemia tyrosine kinase	0.301	Mouse
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.297	Fly
Prrx1	paired related homeobox 1	0.297
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.289
Hand2	heart and neural crest derivatives expressed transcript 2	0.289
Cd22	CD22 antigen	0.283
Spry4	sprouty homolog 4 (Drosophila)	0.276
Cybb	cytochrome b-245, beta polypeptide	0.265	Mouse
Src	Rous sarcoma oncogene	0.251
Agtr2	angiotensin II receptor, type 2	0.251
C1qc	complement component 1, q subcomponent, C chain	0.250	Mouse
Pik3ap1	phosphoinositide-3-kinase adaptor protein 1	0.250
En1	engrailed 1	0.246
Flt4	FMS-like tyrosine kinase 4	0.244	Human Mouse
Lep	leptin	0.236
Fgf8	fibroblast growth factor 8	0.227	Mouse
Braf	Braf transforming gene	0.218
H2-Ab1	histocompatibility 2, class II antigen A, beta 1	0.217
Crhr1	corticotropin releasing hormone receptor 1	0.216
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.215	Mouse
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.213
Nodal	nodal	0.211
Kitl	kit ligand	0.207
Nos1	nitric oxide synthase 1, neuronal	0.200
Sykb	spleen tyrosine kinase	0.200
Kcne1	potassium voltage-gated channel, Isk-related subfamily, member 1	0.191
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.190
Fut1	fucosyltransferase 1	0.189
Myd88	myeloid differentiation primary response gene 88	0.187
Plxnd1	plexin D1	0.187
Mrc1	mannose receptor, C type 1	0.184
C3ar1	complement component 3a receptor 1	0.182
Ccl3	chemokine (C-C motif) ligand 3	0.182	Human
Phldb2	pleckstrin homology-like domain, family B, member 2	0.181
Hcls1	hematopoietic cell specific Lyn substrate 1	0.180
Pik3cb	phosphatidylinositol 3-kinase, catalytic, beta polypeptide	0.179
Ctsk	cathepsin K	0.179
Chrna6	cholinergic receptor, nicotinic, alpha polypeptide 6	0.178
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.177
Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.172
Cd40	CD40 antigen	0.170
Thbd	thrombomodulin	0.170
Nf1	neurofibromatosis 1	0.164
Nos2	nitric oxide synthase 2, inducible	0.159
Apc	adenomatosis polyposis coli	0.159
Ppp2ca	protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform	0.159
Nfib	nuclear factor I/B	0.158
Il2rg	interleukin 2 receptor, gamma chain	0.155
Sox9	SRY-box containing gene 9	0.154
Mefv	Mediterranean fever	0.154
Gja1	gap junction protein, alpha 1	0.151
Tyrobp	TYRO protein tyrosine kinase binding protein	0.151
Laptm5	lysosomal-associated protein transmembrane 5	0.150
Pcsk1	proprotein convertase subtilisin/kexin type 1	0.149
Fgfr2	fibroblast growth factor receptor 2	0.149
Fgg	fibrinogen gamma chain	0.148
Ncf1	neutrophil cytosolic factor 1	0.147
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.146
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.142
C1qb	complement component 1, q subcomponent, beta polypeptide	0.142	Mouse
Slamf8	SLAM family member 8	0.142
Slc15a3	solute carrier family 15, member 3	0.139
Ret	ret proto-oncogene	0.138
Lrrk2	leucine-rich repeat kinase 2	0.137
Ptpn12	protein tyrosine phosphatase, non-receptor type 12	0.134
Col1a1	collagen, type I, alpha 1	0.133
Skil	SKI-like	0.133
Ly86	lymphocyte antigen 86	0.132
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.130
Was	Wiskott-Aldrich syndrome homolog (human)	0.130
Foxa2	forkhead box A2	0.129
Rgs4	regulator of G-protein signaling 4	0.129
Csf1r	colony stimulating factor 1 receptor	0.129
Gucy1b3	guanylate cyclase 1, soluble, beta 3	0.128
Mkl2	MKL/myocardin-like 2	0.128
Traf6	TNF receptor-associated factor 6	0.125
Nlrp3	NLR family, pyrin domain containing 3	0.125	Mouse
Grm1	glutamate receptor, metabotropic 1	0.124
Fcgr3	Fc receptor, IgG, low affinity III	0.123
Ccl4	chemokine (C-C motif) ligand 4	0.121
Zeb1	zinc finger E-box binding homeobox 1	0.121
Ldlr	low density lipoprotein receptor	0.120
Meox2	mesenchyme homeobox 2	0.118
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.118
Ctsw	cathepsin W	0.118
Ece1	endothelin converting enzyme 1	0.117
Ptgs2	prostaglandin-endoperoxide synthase 2	0.116
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.114
Gcet2	germinal center expressed transcript 2	0.113
Gbx2	gastrulation brain homeobox 2	0.112
Mapk1	mitogen-activated protein kinase 1	0.111	Fly
Bmp5	bone morphogenetic protein 5	0.108
Tgfb2	transforming growth factor, beta 2	0.108
Ifngr1	interferon gamma receptor 1	0.107
Abcg1	ATP-binding cassette, sub-family G (WHITE), member 1	0.106
Ptgir	prostaglandin I receptor (IP)	0.106
Cd38	CD38 antigen	0.104
Flt1	FMS-like tyrosine kinase 1	0.102	Mouse
Fyb	FYN binding protein	0.102
Ltbp1	latent transforming growth factor beta binding protein 1	0.102
Rpgrip1l	Rpgrip1-like	0.099
Rgs12	regulator of G-protein signaling 12	0.099
Gdf3	growth differentiation factor 3	0.098	Mouse
Tbx3	T-box 3	0.097
Unc93b1	unc-93 homolog B1 (C. elegans)	0.097
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.097
Ihh	Indian hedgehog	0.097
Sh3bgrl3	SH3 domain binding glutamic acid-rich protein-like 3	0.097
Gdf1	growth differentiation factor 1	0.096	Mouse
Hck	hemopoietic cell kinase	0.095	Mouse
Bcar1	breast cancer anti-estrogen resistance 1	0.094
Aif1	allograft inflammatory factor 1	0.093
Adra2a	adrenergic receptor, alpha 2a	0.092
Bmp2	bone morphogenetic protein 2	0.091	Human Mouse
Prss23	protease, serine, 23	0.090
Homer1	homer homolog 1 (Drosophila)	0.090
Il6	interleukin 6	0.089
Met	met proto-oncogene	0.089
Prkcb	protein kinase C, beta	0.088
Plau	plasminogen activator, urokinase	0.088
Actr3	ARP3 actin-related protein 3 homolog (yeast)	0.088
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.087
Myh10	myosin, heavy polypeptide 10, non-muscle	0.087
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.087	Human
Cyld	cylindromatosis (turban tumor syndrome)	0.087
Gcgr	glucagon receptor	0.087
Plek	pleckstrin	0.086
Ptprb	protein tyrosine phosphatase, receptor type, B	0.086
Trp53	transformation related protein 53	0.086
Nsf	N-ethylmaleimide sensitive fusion protein	0.086
Htr2b	5-hydroxytryptamine (serotonin) receptor 2B	0.086	Human
Gabrd	gamma-aminobutyric acid (GABA) A receptor, subunit delta	0.086
Adra1b	adrenergic receptor, alpha 1b	0.085
Rel	reticuloendotheliosis oncogene	0.084
Dab2	disabled homolog 2 (Drosophila)	0.084
Pax3	paired box gene 3	0.083
Foxd3	forkhead box D3	0.082
Timp3	tissue inhibitor of metalloproteinase 3	0.081
Clec4n	C-type lectin domain family 4, member n	0.080
Fermt2	fermitin family homolog 2 (Drosophila)	0.079
Cxcl2	chemokine (C-X-C motif) ligand 2	0.079
Wnt5a	wingless-related MMTV integration site 5A	0.079
Tgfbr3	transforming growth factor, beta receptor III	0.078
Cd53	CD53 antigen	0.078
Icam1	intercellular adhesion molecule 1	0.078	Human
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.077	Mouse
Tbxas1	thromboxane A synthase 1, platelet	0.077
Ptprc	protein tyrosine phosphatase, receptor type, C	0.077
Socs1	suppressor of cytokine signaling 1	0.076
Fgf7	fibroblast growth factor 7	0.076	Mouse
Fbn1	fibrillin 1	0.075
P2ry6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.074	Mouse
Sfn	stratifin	0.074	Fly
Il10	interleukin 10	0.074
Rock2	Rho-associated coiled-coil containing protein kinase 2	0.074
BC013712	cDNA sequence BC013712	0.073
Lamb1	laminin B1	0.073
Wwtr1	WW domain containing transcription regulator 1	0.073
Mesp1	mesoderm posterior 1	0.073
Itgax	integrin alpha X	0.072
Pycard	PYD and CARD domain containing	0.072
Adam17	a disintegrin and metallopeptidase domain 17	0.071
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.071
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.070
Mapk3	mitogen-activated protein kinase 3	0.069	Human Fly
Ctgf	connective tissue growth factor	0.069	Human
Ccr5	chemokine (C-C motif) receptor 5	0.069
Ccl12	chemokine (C-C motif) ligand 12	0.069
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.069
H2-DMb2	histocompatibility 2, class II, locus Mb2	0.069
Notch2	Notch gene homolog 2 (Drosophila)	0.067
Fli1	Friend leukemia integration 1	0.067
Gab1	growth factor receptor bound protein 2-associated protein 1	0.067
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.067
Il6st	interleukin 6 signal transducer	0.067
Ntn1	netrin 1	0.067
Pou3f1	POU domain, class 3, transcription factor 1	0.066
Htra1	HtrA serine peptidase 1	0.066
Hoxa11	homeobox A11	0.066
Brs3	bombesin-like receptor 3	0.066
Nrg1	neuregulin 1	0.065
Ch25h	cholesterol 25-hydroxylase	0.065
Tlr4	toll-like receptor 4	0.064
Htr1f	5-hydroxytryptamine (serotonin) receptor 1F	0.064
Prkaca	protein kinase, cAMP dependent, catalytic, alpha	0.064
Npy1r	neuropeptide Y receptor Y1	0.063
Rgnef	Rho-guanine nucleotide exchange factor	0.063
AF251705	cDNA sequence AF251705	0.063
Pcdh12	protocadherin 12	0.063
Ptk2b	PTK2 protein tyrosine kinase 2 beta	0.062	Human
Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.062
Pld4	phospholipase D family, member 4	0.062
Stat5a	signal transducer and activator of transcription 5A	0.062
Acan	aggrecan	0.062
Aim2	absent in melanoma 2	0.062
Ric8	resistance to inhibitors of cholinesterase 8 homolog (C. elegans)	0.061
Tnfrsf11b	tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)	0.061
Cckbr	cholecystokinin B receptor	0.061
Lyz1	lysozyme 1	0.061
L1cam	L1 cell adhesion molecule	0.061
Rab3il1	RAB3A interacting protein (rabin3)-like 1	0.061
Hbegf	heparin-binding EGF-like growth factor	0.060
Fgfrl1	fibroblast growth factor receptor-like 1	0.060
Epas1	endothelial PAS domain protein 1	0.060
Sfpi1	SFFV proviral integration 1	0.060
Irf8	interferon regulatory factor 8	0.059
Mdm4	transformed mouse 3T3 cell double minute 4	0.059
Itgb2	integrin beta 2	0.059
Sst	somatostatin	0.059
Smad7	MAD homolog 7 (Drosophila)	0.059
Kcnj3	potassium inwardly-rectifying channel, subfamily J, member 3	0.059
Adrb1	adrenergic receptor, beta 1	0.059
Tnf	tumor necrosis factor	0.059
Nod2	nucleotide-binding oligomerization domain containing 2	0.058
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.058
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.058
Cd180	CD180 antigen	0.058	Mouse
Fstl1	follistatin-like 1	0.058
Htr1d	5-hydroxytryptamine (serotonin) receptor 1D	0.058
Lcp1	lymphocyte cytosolic protein 1	0.057
Itgal	integrin alpha L	0.057
Kcnk4	potassium channel, subfamily K, member 4	0.057
Mpeg1	macrophage expressed gene 1	0.057
Pgr	progesterone receptor	0.057
Slc12a3	solute carrier family 12, member 3	0.057
Dpt	dermatopontin	0.057
Ptprd	protein tyrosine phosphatase, receptor type, D	0.056
Mmp2	matrix metallopeptidase 2	0.056
Map2k2	mitogen-activated protein kinase kinase 2	0.055	Fly
Ppef2	protein phosphatase, EF hand calcium-binding domain 2	0.055
Mgat3	mannoside acetylglucosaminyltransferase 3	0.055
Ptgfr	prostaglandin F receptor	0.055
Rictor	RPTOR independent companion of MTOR, complex 2	0.055
Vegfc	vascular endothelial growth factor C	0.055	Mouse
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.054
Thbs2	thrombospondin 2	0.054
Arid4a	AT rich interactive domain 4A (RBP1-like)	0.054
Cacna1e	calcium channel, voltage-dependent, R type, alpha 1E subunit	0.054
Fgfr3	fibroblast growth factor receptor 3	0.054	Human Mouse
Runx2	runt related transcription factor 2	0.054
Cd68	CD68 antigen	0.054
Hras1	Harvey rat sarcoma virus oncogene 1	0.054	Human Rat
Fgfbp1	fibroblast growth factor binding protein 1	0.054
Fgf23	fibroblast growth factor 23	0.054
Hgf	hepatocyte growth factor	0.054
Sept7	septin 7	0.054
Gaa	glucosidase, alpha, acid	0.054
Grm8	glutamate receptor, metabotropic 8	0.054
Casp8	caspase 8	0.053
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.053
Lysmd3	LysM, putative peptidoglycan-binding, domain containing 3	0.053
Pkdcc	protein kinase domain containing, cytoplasmic	0.052
Oprl1	opioid receptor-like 1	0.052
Mylk	myosin, light polypeptide kinase	0.052
Nedd9	neural precursor cell expressed, developmentally down-regulated gene 9	0.051
Grin2a	glutamate receptor, ionotropic, NMDA2A (epsilon 1)	0.051
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.051
Galnt3	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3	0.051
Pds5b	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.051
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.051
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.050
Jak2	Janus kinase 2	0.050
Igf1	insulin-like growth factor 1	0.050
Tpm4	tropomyosin 4	0.050
Foxi3	forkhead box I3	0.050
Rgs9	regulator of G-protein signaling 9	0.050
Nkx2-1	NK2 homeobox 1	0.050
Socs3	suppressor of cytokine signaling 3	0.050
C1ql1	complement component 1, q subcomponent-like 1	0.049	Mouse
Mgp	matrix Gla protein	0.049
Fgf14	fibroblast growth factor 14	0.049	Mouse
Drd2	dopamine receptor D2	0.049	Rat
Map2k1	mitogen-activated protein kinase kinase 1	0.049	Fly
Rfwd2	ring finger and WD repeat domain 2	0.048
Khdrbs1	KH domain containing, RNA binding, signal transduction associated 1	0.048
Ednrb	endothelin receptor type B	0.047
Pou3f4	POU domain, class 3, transcription factor 4	0.047
Pea15a	phosphoprotein enriched in astrocytes 15A	0.047
Gli3	GLI-Kruppel family member GLI3	0.047
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.047
Socs2	suppressor of cytokine signaling 2	0.047
Ifnar1	interferon (alpha and beta) receptor 1	0.047
Epn1	epsin 1	0.047
Kcnk3	potassium channel, subfamily K, member 3	0.046
Clec7a	C-type lectin domain family 7, member a	0.046
Actr2	ARP2 actin-related protein 2 homolog (yeast)	0.046
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.046
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.046
Ccl24	chemokine (C-C motif) ligand 24	0.046
Sdc3	syndecan 3	0.046
Cyr61	cysteine rich protein 61	0.046
Nckap1l	NCK associated protein 1 like	0.046
Shc3	src homology 2 domain-containing transforming protein C3	0.046
Emcn	endomucin	0.046
F2r	coagulation factor II (thrombin) receptor	0.046
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.045
Cd33	CD33 antigen	0.045
Wt1	Wilms tumor 1 homolog	0.045
Cd300ld	CD300 molecule-like family member d	0.045
Cd4	CD4 antigen	0.045
Prf1	perforin 1 (pore forming protein)	0.045
Tmem204	transmembrane protein 204	0.045
Smn1	survival motor neuron 1	0.045
Folr2	folate receptor 2 (fetal)	0.044
Ikzf1	IKAROS family zinc finger 1	0.044
Nfam1	Nfat activating molecule with ITAM motif 1	0.044
Slc25a48	solute carrier family 25, member 48	0.044
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.044
H2-DMa	histocompatibility 2, class II, locus DMa	0.044
Id1	inhibitor of DNA binding 1	0.044
Foxf1a	forkhead box F1a	0.044
Serping1	serine (or cysteine) peptidase inhibitor, clade G, member 1	0.044
Alox5ap	arachidonate 5-lipoxygenase activating protein	0.044
Cacng3	calcium channel, voltage-dependent, gamma subunit 3	0.044
Capn2	calpain 2	0.044
Kiss1	KiSS-1 metastasis-suppressor	0.043
2310044H10Rik	RIKEN cDNA 2310044H10 gene	0.043
Cacng2	calcium channel, voltage-dependent, gamma subunit 2	0.043
Vdr	vitamin D receptor	0.043
Vcl	vinculin	0.043
Entpd1	ectonucleoside triphosphate diphosphohydrolase 1	0.043
Gm14548	predicted gene 14548	0.043
Zic3	zinc finger protein of the cerebellum 3	0.043
Ptch1	patched homolog 1	0.043
Il18rap	interleukin 18 receptor accessory protein	0.043
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.043
Ep300	E1A binding protein p300	0.043
Capza2	capping protein (actin filament) muscle Z-line, alpha 2	0.043
Eno1	enolase 1, alpha non-neuron	0.043
Tbx5	T-box 5	0.042
Elf4	E74-like factor 4 (ets domain transcription factor)	0.042
Vim	vimentin	0.042
Il1a	interleukin 1 alpha	0.042
Hmgb1	high mobility group box 1	0.042
Twist2	twist homolog 2 (Drosophila)	0.041
Batf2	basic leucine zipper transcription factor, ATF-like 2	0.041
Clec4d	C-type lectin domain family 4, member d	0.041
Tgfbr1	transforming growth factor, beta receptor I	0.041
Pik3c2a	phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide	0.041
Atp1a3	ATPase, Na+/K+ transporting, alpha 3 polypeptide	0.041
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.041
Ids	iduronate 2-sulfatase	0.041
Ahr	aryl-hydrocarbon receptor	0.040
Mapk8	mitogen-activated protein kinase 8	0.040
Pclo	piccolo (presynaptic cytomatrix protein)	0.040
C5ar1	complement component 5a receptor 1	0.040	Human
Hmx3	H6 homeobox 3	0.040
Plcb1	phospholipase C, beta 1	0.040
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.040
Fgf18	fibroblast growth factor 18	0.040
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.040
Cd34	CD34 antigen	0.040
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.039
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.039
Cxcl12	chemokine (C-X-C motif) ligand 12	0.039
Pdcd1lg2	programmed cell death 1 ligand 2	0.039
Prrx2	paired related homeobox 2	0.039
Foxb1	forkhead box B1	0.039
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.039
Stat3	signal transducer and activator of transcription 3	0.039
Has2	hyaluronan synthase 2	0.039
Ccl22	chemokine (C-C motif) ligand 22	0.039
Gpr33	G protein-coupled receptor 33	0.039
Bmp6	bone morphogenetic protein 6	0.039
Ngf	nerve growth factor	0.039
Cd83	CD83 antigen	0.038
Arl10	ADP-ribosylation factor-like 10	0.038
Htr2c	5-hydroxytryptamine (serotonin) receptor 2C	0.038	Human
Calcrl	calcitonin receptor-like	0.038
Msr1	macrophage scavenger receptor 1	0.038
Rock1	Rho-associated coiled-coil containing protein kinase 1	0.038
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.038
Chd2	chromodomain helicase DNA binding protein 2	0.038
Pilrb1	paired immunoglobin-like type 2 receptor beta 1	0.038
Adcy8	adenylate cyclase 8	0.038
Tbx10	T-box 10	0.038
Pdgfc	platelet-derived growth factor, C polypeptide	0.038
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.038
Il1rn	interleukin 1 receptor antagonist	0.038
Grap2	GRB2-related adaptor protein 2	0.038
Nck1	non-catalytic region of tyrosine kinase adaptor protein 1	0.038
Prkcc	protein kinase C, gamma	0.038
Clnk	cytokine-dependent hematopoietic cell linker	0.038
Spnb2	spectrin beta 2	0.037
Chst2	carbohydrate sulfotransferase 2	0.037
Mme	membrane metallo endopeptidase	0.037
Foxc2	forkhead box C2	0.037
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.037
Il1r1	interleukin 1 receptor, type I	0.037
Tm4sf1	transmembrane 4 superfamily member 1	0.037
Rab14	RAB14, member RAS oncogene family	0.036
Tll1	tolloid-like	0.036
Bcan	brevican	0.036
Gata3	GATA binding protein 3	0.036
Cdk5r2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.036
Dppa3	developmental pluripotency-associated 3	0.036
Ramp2	receptor (calcitonin) activity modifying protein 2	0.036
Thbs1	thrombospondin 1	0.036
Smad2	MAD homolog 2 (Drosophila)	0.036
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.036
Sqstm1	sequestosome 1	0.036
Cyth4	cytohesin 4	0.036
Dok2	docking protein 2	0.035
Trak2	trafficking protein, kinesin binding 2	0.035
Picalm	phosphatidylinositol binding clathrin assembly protein	0.035
Naalad2	N-acetylated alpha-linked acidic dipeptidase 2	0.035
Pam	peptidylglycine alpha-amidating monooxygenase	0.035
Gpr83	G protein-coupled receptor 83	0.035
Npy2r	neuropeptide Y receptor Y2	0.035
Snai1	snail homolog 1 (Drosophila)	0.035
Pkd2	polycystic kidney disease 2	0.035
Gng11	guanine nucleotide binding protein (G protein), gamma 11	0.034
Edn1	endothelin 1	0.034
Sema3c	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	0.034
Adora2b	adenosine A2b receptor	0.034
Il22	interleukin 22	0.034
Sdpr	serum deprivation response	0.034	Mouse
Itga5	integrin alpha 5 (fibronectin receptor alpha)	0.034
Ubd	ubiquitin D	0.034
Prss32	protease, serine, 32	0.034
Trim47	tripartite motif-containing 47	0.034
Cdx2	caudal type homeobox 2	0.034
Il2rb	interleukin 2 receptor, beta chain	0.034
Hdac2	histone deacetylase 2	0.034
Cel	carboxyl ester lipase	0.033
Grpr	gastrin releasing peptide receptor	0.033
Npy5r	neuropeptide Y receptor Y5	0.033
Eltd1	EGF, latrophilin seven transmembrane domain containing 1	0.033
Myo1f	myosin IF	0.033
Kcns2	K+ voltage-gated channel, subfamily S, 2	0.033
Il2	interleukin 2	0.033
Prdm1	PR domain containing 1, with ZNF domain	0.033
Has1	hyaluronan synthase1	0.033
Klra5	killer cell lectin-like receptor, subfamily A, member 5	0.033
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.033
Wwc2	WW, C2 and coiled-coil domain containing 2	0.032
Klra17	killer cell lectin-like receptor, subfamily A, member 17	0.032
Huwe1	HECT, UBA and WWE domain containing 1	0.032
Tlr6	toll-like receptor 6	0.032	Mouse
Timp1	tissue inhibitor of metalloproteinase 1	0.032
Lair1	leukocyte-associated Ig-like receptor 1	0.032
Npr3	natriuretic peptide receptor 3	0.032
Mpdz	multiple PDZ domain protein	0.032
Sirpa	signal-regulatory protein alpha	0.032
Gpr182	G protein-coupled receptor 182	0.032
Sox7	SRY-box containing gene 7	0.032
Ccr10	chemokine (C-C motif) receptor 10	0.032
Snai2	snail homolog 2 (Drosophila)	0.032
Drd1a	dopamine receptor D1A	0.032
Rab3a	RAB3A, member RAS oncogene family	0.031
Irg1	immunoresponsive gene 1	0.031
Gja3	gap junction protein, alpha 3	0.031
P2ry13	purinergic receptor P2Y, G-protein coupled 13	0.031
Ncoa3	nuclear receptor coactivator 3	0.031
Cdhr5	cadherin-related family member 5	0.031
Trpc6	transient receptor potential cation channel, subfamily C, member 6	0.031
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.031
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.031
Ddr2	discoidin domain receptor family, member 2	0.031
Rcvrn	recoverin	0.031
Hapln1	hyaluronan and proteoglycan link protein 1	0.031
Ckb	creatine kinase, brain	0.031
Idua	iduronidase, alpha-L-	0.031
Prkd3	protein kinase D3	0.030	Mouse
Tdgf1	teratocarcinoma-derived growth factor 1	0.030
Itga8	integrin alpha 8	0.030
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.030
Wdr26	WD repeat domain 26	0.030
Otp	orthopedia homolog (Drosophila)	0.030
Abpd	androgen binding protein delta	0.030
Muc13	mucin 13, epithelial transmembrane	0.030
Syt6	synaptotagmin VI	0.030
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.030
Ctss	cathepsin S	0.030
Mas1	MAS1 oncogene	0.030
Irf6	interferon regulatory factor 6	0.030
Smo	smoothened homolog (Drosophila)	0.030
Rbpjl	recombination signal binding protein for immunoglobulin kappa J region-like	0.030
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.030
Zfr	zinc finger RNA binding protein	0.030
Lox	lysyl oxidase	0.030
Rps6ka3	ribosomal protein S6 kinase polypeptide 3	0.030
Mtpn	myotrophin	0.030
Cacnb2	calcium channel, voltage-dependent, beta 2 subunit	0.030
Wbp2	WW domain binding protein 2	0.030
Cer1	cerberus 1 homolog (Xenopus laevis)	0.030
Ctnnb1	catenin (cadherin associated protein), beta 1	0.030
Tnfrsf8	tumor necrosis factor receptor superfamily, member 8	0.030
Pou3f3	POU domain, class 3, transcription factor 3	0.030
Ms4a7	membrane-spanning 4-domains, subfamily A, member 7	0.030
Cd80	CD80 antigen	0.030
Fpr-rs4	formyl peptide receptor, related sequence 4	0.030
Oprk1	opioid receptor, kappa 1	0.029
Bai1	brain-specific angiogenesis inhibitor 1	0.029
Cnn3	calponin 3, acidic	0.029
Agmat	agmatine ureohydrolase (agmatinase)	0.029
Irs1	insulin receptor substrate 1	0.029
Cdh8	cadherin 8	0.029
Dock5	dedicator of cytokinesis 5	0.029
Cd5	CD5 antigen	0.029
Fkbp9	FK506 binding protein 9	0.029
Axl	AXL receptor tyrosine kinase	0.029
Fpr3	formyl peptide receptor 3	0.029
Smad4	MAD homolog 4 (Drosophila)	0.029
Ccar1	cell division cycle and apoptosis regulator 1	0.029
Hoxd11	homeobox D11	0.029
Ptger3	prostaglandin E receptor 3 (subtype EP3)	0.029
Nmur2	neuromedin U receptor 2	0.029
Ripply3	ripply3 homolog (zebrafish)	0.029
Akap12	A kinase (PRKA) anchor protein (gravin) 12	0.029
Prlhr	prolactin releasing hormone receptor	0.029
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.028	Mouse
Clec14a	C-type lectin domain family 14, member a	0.028
Il10ra	interleukin 10 receptor, alpha	0.028
Ccr1l1	chemokine (C-C motif) receptor 1-like 1	0.028	Human
Erbb2ip	Erbb2 interacting protein	0.028
Arhgap30	Rho GTPase activating protein 30	0.028
Fxyd7	FXYD domain-containing ion transport regulator 7	0.028
Casr	calcium-sensing receptor	0.028
Ms4a6c	membrane-spanning 4-domains, subfamily A, member 6C	0.028
Mobp	myelin-associated oligodendrocytic basic protein	0.028
Sh3pxd2b	SH3 and PX domains 2B	0.028
Bgn	biglycan	0.028
Fgf12	fibroblast growth factor 12	0.028	Mouse
Fgf5	fibroblast growth factor 5	0.028	Mouse
Rab10	RAB10, member RAS oncogene family	0.028
Arhgap6	Rho GTPase activating protein 6	0.028
Traf2	TNF receptor-associated factor 2	0.028
Dusp6	dual specificity phosphatase 6	0.028
Mmp8	matrix metallopeptidase 8	0.028
Cckar	cholecystokinin A receptor	0.028
Myadm	myeloid-associated differentiation marker	0.028
Ube2d2	ubiquitin-conjugating enzyme E2D 2	0.028
Rap2a	RAS related protein 2a	0.028	Mouse
Osmr	oncostatin M receptor	0.027
Trp73	transformation related protein 73	0.027
Rac2	RAS-related C3 botulinum substrate 2	0.027
Cdh6	cadherin 6	0.027
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.027
Acta2	actin, alpha 2, smooth muscle, aorta	0.027
Apbb1ip	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	0.027
Pdcd10	programmed cell death 10	0.027
Tspan10	tetraspanin 10	0.027
Actn2	actinin alpha 2	0.027
Bmper	BMP-binding endothelial regulator	0.027
Phlda3	pleckstrin homology-like domain, family A, member 3	0.027
Nhedc2	Na+/H+ exchanger domain containing 2	0.027
Pds5a	PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)	0.027
Gjb6	gap junction protein, beta 6	0.027
Vcam1	vascular cell adhesion molecule 1	0.027
Fbxw7	F-box and WD-40 domain protein 7	0.027	Human
Plcg2	phospholipase C, gamma 2	0.027
Cdipt	CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)	0.027
Ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.027
Ncam2	neural cell adhesion molecule 2	0.027
Bhlhe22	basic helix-loop-helix family, member e22	0.027
Krt84	keratin 84	0.027
Lmx1a	LIM homeobox transcription factor 1 alpha	0.027
Ebi3	Epstein-Barr virus induced gene 3	0.027
Evx1	even skipped homeotic gene 1 homolog	0.027
Oprd1	opioid receptor, delta 1	0.027
Dsg2	desmoglein 2	0.027
Adra1a	adrenergic receptor, alpha 1a	0.026	Rat
Nfkbie	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.026
Itga3	integrin alpha 3	0.026
Lama2	laminin, alpha 2	0.026
Col12a1	collagen, type XII, alpha 1	0.026
Bmx	BMX non-receptor tyrosine kinase	0.026
Ripk4	receptor-interacting serine-threonine kinase 4	0.026	Mouse
Gata6	GATA binding protein 6	0.026
Lif	leukemia inhibitory factor	0.026
Abcg3	ATP-binding cassette, sub-family G (WHITE), member 3	0.026
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.026
Gpr84	G protein-coupled receptor 84	0.026
Cd300a	CD300A antigen	0.026
Cdh1	cadherin 1	0.026
Lrp1	low density lipoprotein receptor-related protein 1	0.026
Pls3	plastin 3 (T-isoform)	0.026
Myo1g	myosin IG	0.026
Pomc	pro-opiomelanocortin-alpha	0.026
Sh3bp2	SH3-domain binding protein 2	0.026
Naip1	NLR family, apoptosis inhibitory protein 1	0.026
Cxcl14	chemokine (C-X-C motif) ligand 14	0.026
Tnfsf9	tumor necrosis factor (ligand) superfamily, member 9	0.026
Apoe	apolipoprotein E	0.026
Gpr132	G protein-coupled receptor 132	0.026
Lats2	large tumor suppressor 2	0.026
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.026
Ptpre	protein tyrosine phosphatase, receptor type, E	0.026
Itga6	integrin alpha 6	0.026
Hcrt	hypocretin	0.026
Pax2	paired box gene 2	0.026
Zfpm2	zinc finger protein, multitype 2	0.026
Irf1	interferon regulatory factor 1	0.026
Rhox6	reproductive homeobox 6	0.026
Lcp2	lymphocyte cytosolic protein 2	0.026
Gabrb3	gamma-aminobutyric acid (GABA) A receptor, subunit beta 3	0.026
Cd28	CD28 antigen	0.026
Tff1	trefoil factor 1	0.026	Mouse
Sod3	superoxide dismutase 3, extracellular	0.026
Clock	circadian locomotor output cycles kaput	0.025
Hpca	hippocalcin	0.025
Nt5e	5' nucleotidase, ecto	0.025
Srpx2	sushi-repeat-containing protein, X-linked 2	0.025
Hnf4a	hepatic nuclear factor 4, alpha	0.025
Ache	acetylcholinesterase	0.025
Foxb2	forkhead box B2	0.025
Tnfsf8	tumor necrosis factor (ligand) superfamily, member 8	0.025
Chd7	chromodomain helicase DNA binding protein 7	0.025
Ikbkb	inhibitor of kappaB kinase beta	0.025
Oc90	otoconin 90	0.025
Htr6	5-hydroxytryptamine (serotonin) receptor 6	0.025
Glra1	glycine receptor, alpha 1 subunit	0.025
Phospho1	phosphatase, orphan 1	0.025
Mcoln2	mucolipin 2	0.025
Nos3	nitric oxide synthase 3, endothelial cell	0.025
Mep1a	meprin 1 alpha	0.025
Mcpt2	mast cell protease 2	0.025
Vat1	vesicle amine transport protein 1 homolog (T californica)	0.025
Onecut3	one cut domain, family member 3	0.025
Cd74	CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)	0.025
Ccr7	chemokine (C-C motif) receptor 7	0.025
Xcr1	chemokine (C motif) receptor 1	0.025
1810019J16Rik	RIKEN cDNA 1810019J16 gene	0.025
Pcyt1a	phosphate cytidylyltransferase 1, choline, alpha isoform	0.025
Ntf3	neurotrophin 3	0.025
Ogn	osteoglycin	0.025
Il1rap	interleukin 1 receptor accessory protein	0.025
Ankrd17	ankyrin repeat domain 17	0.025
Tph1	tryptophan hydroxylase 1	0.025
Pvr	poliovirus receptor	0.024
Gja5	gap junction protein, alpha 5	0.024
Shank2	SH3/ankyrin domain gene 2	0.024
Zbtb7a	zinc finger and BTB domain containing 7a	0.024
Angpt4	angiopoietin 4	0.024
Mid1	midline 1	0.024
Mdm2	transformed mouse 3T3 cell double minute 2	0.024
Etv1	ets variant gene 1	0.024
Blnk	B-cell linker	0.024
Gfpt2	glutamine fructose-6-phosphate transaminase 2	0.024
Ccl8	chemokine (C-C motif) ligand 8	0.024
Dynlt1b	dynein light chain Tctex-type 1D	0.024
Slfn4	schlafen 4	0.024
Sema3b	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	0.024
Tcstv1	2-cell-stage, variable group, member 1	0.024
Capza1	capping protein (actin filament) muscle Z-line, alpha 1	0.024
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.024
Cfp	complement factor properdin	0.024
Igfbp7	insulin-like growth factor binding protein 7	0.024
Siglece	sialic acid binding Ig-like lectin E	0.024
Zcchc6	zinc finger, CCHC domain containing 6	0.024
Mbp	myelin basic protein	0.024
Sgpl1	sphingosine phosphate lyase 1	0.024
Efemp1	epidermal growth factor-containing fibulin-like extracellular matrix protein 1	0.024
Dnase1l3	deoxyribonuclease 1-like 3	0.024
Pdx1	pancreatic and duodenal homeobox 1	0.023
Adra2b	adrenergic receptor, alpha 2b	0.023
Gnat1	guanine nucleotide binding protein, alpha transducing 1	0.023
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.023
Tsc2	tuberous sclerosis 2	0.023
Ltbp2	latent transforming growth factor beta binding protein 2	0.023
Ccm2	cerebral cavernous malformation 2 homolog (human)	0.023
She	src homology 2 domain-containing transforming protein E	0.023
Cd2ap	CD2-associated protein	0.023
Grb7	growth factor receptor bound protein 7	0.023
Olfr71	olfactory receptor 71	0.023
Gbgt1	globoside alpha-1,3-N-acetylgalactosaminyltransferase 1	0.023
Ube2n	ubiquitin-conjugating enzyme E2N	0.023
Pion	pigeon homolog (Drosophila)	0.023
Csnk2b	casein kinase 2, beta polypeptide	0.023
Gdf15	growth differentiation factor 15	0.023
Gdnf	glial cell line derived neurotrophic factor	0.023
H2-M2	histocompatibility 2, M region locus 2	0.023
Klhl6	kelch-like 6 (Drosophila)	0.023
Trem3	triggering receptor expressed on myeloid cells 3	0.023
Ciita	class II transactivator	0.023	Mouse
Pikfyve	phosphoinositide kinase, FYVE finger containing	0.023
P2ry12	purinergic receptor P2Y, G-protein coupled 12	0.023
Edil3	EGF-like repeats and discoidin I-like domains 3	0.023	Mouse
Fgf4	fibroblast growth factor 4	0.023	Human Mouse
Pmp22	peripheral myelin protein 22	0.023
Cpe	carboxypeptidase E	0.023
Figf	c-fos induced growth factor	0.023	Mouse
Ccbp2	chemokine binding protein 2	0.023
Fpr1	formyl peptide receptor 1	0.023