IMP: Integrative Multi-species Prediction

Mus musculus

77 genes annotated in mouse

erk1 and erk2 cascade

An intracellular protein kinase cascade containing at least ERK1 or ERK2 (MAPKs), a MEK (a MAPKK) and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "erk1 and erk2 cascade"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "erk1 and erk2 cascade" (in gray)

Name	Description	Probability	Func Analog Organism
Lepr	leptin receptor	0.995
Grb2	growth factor receptor bound protein 2	0.994
Inpp5d	inositol polyphosphate-5-phosphatase D	0.988
Pten	phosphatase and tensin homolog	0.967
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.954
Kl	klotho	0.953
Csf1	colony stimulating factor 1 (macrophage)	0.953
Nf1	neurofibromatosis 1	0.906	Zebrafish
Ikzf1	IKAROS family zinc finger 1	0.896
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.887	Human Mouse
Btk	Bruton agammaglobulinemia tyrosine kinase	0.875	Mouse
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.874
Cd44	CD44 antigen	0.861
Dok1	docking protein 1	0.835	Mouse
Col1a1	collagen, type I, alpha 1	0.825
Lyz2	lysozyme 2	0.817
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.779
Plcg1	phospholipase C, gamma 1	0.779
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.778
Cbl	Casitas B-lineage lymphoma	0.774
Tgfbr2	transforming growth factor, beta receptor II	0.745
Acvr1	activin A receptor, type 1	0.736
Dok2	docking protein 2	0.726	Mouse
Trp53	transformation related protein 53	0.686
Fas	Fas (TNF receptor superfamily member 6)	0.668
Nos2	nitric oxide synthase 2, inducible	0.645
Tnf	tumor necrosis factor	0.618	Mouse
Cd247	CD247 antigen	0.611
Cd22	CD22 antigen	0.605
Meox2	mesenchyme homeobox 2	0.602
Vegfa	vascular endothelial growth factor A	0.592
Ptprc	protein tyrosine phosphatase, receptor type, C	0.580
Cav1	caveolin 1, caveolae protein	0.578
Pgr	progesterone receptor	0.572
Igh	immunoglobulin heavy chain complex	0.558
Ifng	interferon gamma	0.554
Prkce	protein kinase C, epsilon	0.552
H2-Ab1	histocompatibility 2, class II antigen A, beta 1	0.552
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.550
Ccr1	chemokine (C-C motif) receptor 1	0.547	Human
Ccl2	chemokine (C-C motif) ligand 2	0.522
Ccr2	chemokine (C-C motif) receptor 2	0.518
Src	Rous sarcoma oncogene	0.516
Il10	interleukin 10	0.498
Il1r1	interleukin 1 receptor, type I	0.483
Plxnd1	plexin D1	0.471
Ptpn12	protein tyrosine phosphatase, non-receptor type 12	0.466
Tlr4	toll-like receptor 4	0.465
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.454
Pax3	paired box gene 3	0.446
Csf1r	colony stimulating factor 1 receptor	0.445
Arrb2	arrestin, beta 2	0.426	Human Mouse
Prf1	perforin 1 (pore forming protein)	0.425
Ltb	lymphotoxin B	0.421
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.419
Il2rg	interleukin 2 receptor, gamma chain	0.409
Cd40	CD40 antigen	0.408
Mmp9	matrix metallopeptidase 9	0.397
Elf4	E74-like factor 4 (ets domain transcription factor)	0.381
Mas1	MAS1 oncogene	0.380
Il18rap	interleukin 18 receptor accessory protein	0.378
Fgf10	fibroblast growth factor 10	0.367
Ret	ret proto-oncogene	0.361
Runx2	runt related transcription factor 2	0.359
Itgb3	integrin beta 3	0.353
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.353
Zeb1	zinc finger E-box binding homeobox 1	0.349
Ednra	endothelin receptor type A	0.348	Rat
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.347
Itgal	integrin alpha L	0.344	Mouse
Tcf21	transcription factor 21	0.335
Cd19	CD19 antigen	0.330
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.322
Nodal	nodal	0.320
Eng	endoglin	0.313
Pdcd1	programmed cell death 1	0.311
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.302
Cckbr	cholecystokinin B receptor	0.298	Rat
Egfr	epidermal growth factor receptor	0.298
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.288
Shh	sonic hedgehog	0.287
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.285
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.283
Raf1	v-raf-leukemia viral oncogene 1	0.282	Mouse Fly
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.281	Mouse
Shc1	src homology 2 domain-containing transforming protein C1	0.280
Apoa1	apolipoprotein A-I	0.279
Fgfr2	fibroblast growth factor receptor 2	0.278
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.278
Cx3cr1	chemokine (C-X3-C) receptor 1	0.273
Ccl4	chemokine (C-C motif) ligand 4	0.272
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.270
Tgfb1	transforming growth factor, beta 1	0.267
Mkl2	MKL/myocardin-like 2	0.262
C1qa	complement component 1, q subcomponent, alpha polypeptide	0.261
Cd80	CD80 antigen	0.261
Fgf8	fibroblast growth factor 8	0.259	Mouse
Mapk1	mitogen-activated protein kinase 1	0.257	Human Fly
Drd2	dopamine receptor D2	0.255	Rat
H2-DMa	histocompatibility 2, class II, locus DMa	0.254
Fyn	Fyn proto-oncogene	0.253	Mouse
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.249
Mrc1	mannose receptor, C type 1	0.243
Insr	insulin receptor	0.242	Mouse
Grb10	growth factor receptor bound protein 10	0.239
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.238
Slc12a1	solute carrier family 12, member 1	0.238
Plcg2	phospholipase C, gamma 2	0.236
Vav1	vav 1 oncogene	0.235
Kiss1	KiSS-1 metastasis-suppressor	0.234
Ghr	growth hormone receptor	0.234
Ins2	insulin II	0.233	Mouse
Nfam1	Nfat activating molecule with ITAM motif 1	0.227
Acan	aggrecan	0.225
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.215
Nsf	N-ethylmaleimide sensitive fusion protein	0.215
Myo1f	myosin IF	0.214
Ccr5	chemokine (C-C motif) receptor 5	0.214
Prrx1	paired related homeobox 1	0.213
Bmp15	bone morphogenetic protein 15	0.212
Pik3ap1	phosphoinositide-3-kinase adaptor protein 1	0.211
Vasp	vasodilator-stimulated phosphoprotein	0.211
Ctgf	connective tissue growth factor	0.210	Human
En2	engrailed 2	0.209
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.208
Grm1	glutamate receptor, metabotropic 1	0.207
Sykb	spleen tyrosine kinase	0.207
Tgfb2	transforming growth factor, beta 2	0.206
Fcgr1	Fc receptor, IgG, high affinity I	0.204
C1qc	complement component 1, q subcomponent, C chain	0.201	Mouse
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.197
Phox2b	paired-like homeobox 2b	0.196
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.195	Fly
Htr4	5 hydroxytryptamine (serotonin) receptor 4	0.193	Mouse
Pds5b	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.192
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.191
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.190
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.188
Smo	smoothened homolog (Drosophila)	0.186
Ptprb	protein tyrosine phosphatase, receptor type, B	0.186
C3ar1	complement component 3a receptor 1	0.186
Gli3	GLI-Kruppel family member GLI3	0.180
Tbx21	T-box 21	0.176
Htr1d	5-hydroxytryptamine (serotonin) receptor 1D	0.176	Mouse
Cdh6	cadherin 6	0.176
C5ar1	complement component 5a receptor 1	0.175	Human
Dab1	disabled homolog 1 (Drosophila)	0.173
Kcnj1	potassium inwardly-rectifying channel, subfamily J, member 1	0.169
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.169
Bmp5	bone morphogenetic protein 5	0.168
Apc	adenomatosis polyposis coli	0.168
Gabrd	gamma-aminobutyric acid (GABA) A receptor, subunit delta	0.167
Ece1	endothelin converting enzyme 1	0.167	Rat
Hnf4a	hepatic nuclear factor 4, alpha	0.166
Fli1	Friend leukemia integration 1	0.166
Pparg	peroxisome proliferator activated receptor gamma	0.164
Cer1	cerberus 1 homolog (Xenopus laevis)	0.163
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.162
Acvrl1	activin A receptor, type II-like 1	0.159
Ntn1	netrin 1	0.159
Sycn	syncollin	0.159
Il22	interleukin 22	0.157
Itga5	integrin alpha 5 (fibronectin receptor alpha)	0.156	Mouse
Isl1	ISL1 transcription factor, LIM/homeodomain	0.154
Zic3	zinc finger protein of the cerebellum 3	0.153
Brs3	bombesin-like receptor 3	0.153
Tyrobp	TYRO protein tyrosine kinase binding protein	0.152
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.152	Mouse
Pthlh	parathyroid hormone-like peptide	0.152
Vav2	vav 2 oncogene	0.151
Foxg1	forkhead box G1	0.151
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.148
Sbpl	spermine binding protein-like	0.147
Kitl	kit ligand	0.146
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.146
Thbd	thrombomodulin	0.145
Ldlr	low density lipoprotein receptor	0.145
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.145
Hhex	hematopoietically expressed homeobox	0.143
Arrb1	arrestin, beta 1	0.143
Crhr1	corticotropin releasing hormone receptor 1	0.143
Rel	reticuloendotheliosis oncogene	0.142
Nrp1	neuropilin 1	0.141
Ltbp1	latent transforming growth factor beta binding protein 1	0.140
Nos1	nitric oxide synthase 1, neuronal	0.140
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.138	Human
Ctsw	cathepsin W	0.138
Gpr83	G protein-coupled receptor 83	0.138
Grm8	glutamate receptor, metabotropic 8	0.138
Kdr	kinase insert domain protein receptor	0.138	Human Mouse
Htr7	5-hydroxytryptamine (serotonin) receptor 7	0.134
Flt1	FMS-like tyrosine kinase 1	0.132	Mouse
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.132
Ptch1	patched homolog 1	0.132
Ncf1	neutrophil cytosolic factor 1	0.131
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.131
Lrrk2	leucine-rich repeat kinase 2	0.131
Fgf4	fibroblast growth factor 4	0.130	Human Mouse
Npy5r	neuropeptide Y receptor Y5	0.130
Atf2	activating transcription factor 2	0.129
Pdgfb	platelet derived growth factor, B polypeptide	0.128	Human Mouse
H2-DMb2	histocompatibility 2, class II, locus Mb2	0.125
Gbx2	gastrulation brain homeobox 2	0.124
Htr2c	5-hydroxytryptamine (serotonin) receptor 2C	0.124	Human Mouse
Was	Wiskott-Aldrich syndrome homolog (human)	0.124
Edn1	endothelin 1	0.124
Ivl	involucrin	0.124
Mc5r	melanocortin 5 receptor	0.123
Cybb	cytochrome b-245, beta polypeptide	0.123	Mouse
Rictor	RPTOR independent companion of MTOR, complex 2	0.123
Tgfbr3	transforming growth factor, beta receptor III	0.123
Apoe	apolipoprotein E	0.123
Spry4	sprouty homolog 4 (Drosophila)	0.122	Mouse
Rdh8	retinol dehydrogenase 8	0.122
Ptk2	PTK2 protein tyrosine kinase 2	0.122
Wnt7a	wingless-related MMTV integration site 7A	0.122
Pde6a	phosphodiesterase 6A, cGMP-specific, rod, alpha	0.122
Braf	Braf transforming gene	0.122
Foxn1	forkhead box N1	0.121
Muc13	mucin 13, epithelial transmembrane	0.121
Tlr2	toll-like receptor 2	0.121	Mouse
Il7	interleukin 7	0.121
Mapk8	mitogen-activated protein kinase 8	0.120
Ifngr1	interferon gamma receptor 1	0.120
Cxcl13	chemokine (C-X-C motif) ligand 13	0.118
Cacna1e	calcium channel, voltage-dependent, R type, alpha 1E subunit	0.117
Pnpla2	patatin-like phospholipase domain containing 2	0.116
Rasgrp1	RAS guanyl releasing protein 1	0.116
Mcl1	myeloid cell leukemia sequence 1	0.116
Pou3f1	POU domain, class 3, transcription factor 1	0.115
Plxna1	plexin A1	0.115
Igf2r	insulin-like growth factor 2 receptor	0.114
Nos3	nitric oxide synthase 3, endothelial cell	0.114
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.112
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.112
Colq	collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase	0.111
Map3k3	mitogen-activated protein kinase kinase kinase 3	0.110
Bcl6b	B-cell CLL/lymphoma 6, member B	0.109
Ccl22	chemokine (C-C motif) ligand 22	0.109
Ren1	renin 1 structural	0.108
Htr1f	5-hydroxytryptamine (serotonin) receptor 1F	0.107	Mouse
Tnks1bp1	tankyrase 1 binding protein 1	0.107
Ppp2ca	protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform	0.106
Gast	gastrin	0.106
Bai1	brain-specific angiogenesis inhibitor 1	0.105
Lmna	lamin A	0.105
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.104
Tspo2	translocator protein 2	0.104
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.104
Oprl1	opioid receptor-like 1	0.104
Drd4	dopamine receptor D4	0.104
Umod	uromodulin	0.103
Hrh1	histamine receptor H1	0.103
Fgf5	fibroblast growth factor 5	0.102	Mouse
Kcnk4	potassium channel, subfamily K, member 4	0.101
Smad4	MAD homolog 4 (Drosophila)	0.101
Ncr1	natural cytotoxicity triggering receptor 1	0.101
Sox9	SRY-box containing gene 9	0.101
Socs2	suppressor of cytokine signaling 2	0.101
En1	engrailed 1	0.101
Prkcb	protein kinase C, beta	0.100
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.100
Bdnf	brain derived neurotrophic factor	0.100
Inhbc	inhibin beta-C	0.100
Stx1b	syntaxin 1B	0.099
Homer1	homer homolog 1 (Drosophila)	0.097
Chrna6	cholinergic receptor, nicotinic, alpha polypeptide 6	0.097
Sod3	superoxide dismutase 3, extracellular	0.097
Ccr1l1	chemokine (C-C motif) receptor 1-like 1	0.096	Human
Met	met proto-oncogene	0.096
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.096
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.096
Kctd10	potassium channel tetramerisation domain containing 10	0.095
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.095
Jag2	jagged 2	0.095
Bmp4	bone morphogenetic protein 4	0.095
Cyld	cylindromatosis (turban tumor syndrome)	0.094
Cxcl12	chemokine (C-X-C motif) ligand 12	0.094
Ubd	ubiquitin D	0.094
Stat6	signal transducer and activator of transcription 6	0.093
Nckap1l	NCK associated protein 1 like	0.093
Nkx3-1	NK-3 transcription factor, locus 1 (Drosophila)	0.093
Cckar	cholecystokinin A receptor	0.093
Nrg1	neuregulin 1	0.093
Kcns2	K+ voltage-gated channel, subfamily S, 2	0.092
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.092
Lcp1	lymphocyte cytosolic protein 1	0.092
Crhr2	corticotropin releasing hormone receptor 2	0.091	Rat
Slc22a2	solute carrier family 22 (organic cation transporter), member 2	0.091
Flt4	FMS-like tyrosine kinase 4	0.090	Human Mouse
Socs3	suppressor of cytokine signaling 3	0.090
Lta	lymphotoxin A	0.090	Mouse
Rara	retinoic acid receptor, alpha	0.090
Ptk2b	PTK2 protein tyrosine kinase 2 beta	0.090	Human
Zp1	zona pellucida glycoprotein 1	0.090
Cd86	CD86 antigen	0.090	Mouse
Bcl6	B-cell leukemia/lymphoma 6	0.089
Il10ra	interleukin 10 receptor, alpha	0.089
Stat3	signal transducer and activator of transcription 3	0.089
AF251705	cDNA sequence AF251705	0.089
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.089
Jak2	Janus kinase 2	0.089
Blnk	B-cell linker	0.089
Rgs4	regulator of G-protein signaling 4	0.089
Fgg	fibrinogen gamma chain	0.088
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.088
Adra2b	adrenergic receptor, alpha 2b	0.088	Mouse
Myh9	myosin, heavy polypeptide 9, non-muscle	0.088
Myo1c	myosin IC	0.088
Sell	selectin, lymphocyte	0.088
Tek	endothelial-specific receptor tyrosine kinase	0.088	Human
Foxd3	forkhead box D3	0.087
Rc3h1	RING CCCH (C3H) domains 1	0.087
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.087
Bcan	brevican	0.087
Itga1	integrin alpha 1	0.087	Mouse
Sh2d2a	SH2 domain protein 2A	0.087
Lrrc8c	leucine rich repeat containing 8 family, member C	0.086
Ywhae	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.086	Fly
Entpd1	ectonucleoside triphosphate diphosphohydrolase 1	0.086
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.085
Trpc4	transient receptor potential cation channel, subfamily C, member 4	0.085
Lif	leukemia inhibitory factor	0.085
Bdkrb2	bradykinin receptor, beta 2	0.085
Pou3f3	POU domain, class 3, transcription factor 3	0.085
Kcnq2	potassium voltage-gated channel, subfamily Q, member 2	0.084
Gpr3	G-protein coupled receptor 3	0.084
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.084
Il15	interleukin 15	0.084
Chrm1	cholinergic receptor, muscarinic 1, CNS	0.084
Thbs1	thrombospondin 1	0.084
Ptpra	protein tyrosine phosphatase, receptor type, A	0.083
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.083
Ptgs2	prostaglandin-endoperoxide synthase 2	0.083
Casp8	caspase 8	0.083
Igf1r	insulin-like growth factor I receptor	0.083	Mouse
Itga4	integrin alpha 4	0.083	Mouse
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.082
Cd4	CD4 antigen	0.081
Prss32	protease, serine, 32	0.081
Gpr33	G protein-coupled receptor 33	0.081
Tcfap2a	transcription factor AP-2, alpha	0.081
Kcnj3	potassium inwardly-rectifying channel, subfamily J, member 3	0.081
Chrd	chordin	0.080
Col19a1	collagen, type XIX, alpha 1	0.080
Abl2	v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)	0.080
Col4a1	collagen, type IV, alpha 1	0.080
Qk	quaking	0.080
Laptm5	lysosomal-associated protein transmembrane 5	0.080
Cel	carboxyl ester lipase	0.079
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.079
Sox10	SRY-box containing gene 10	0.079	Mouse
Il1rap	interleukin 1 receptor accessory protein	0.079
Cdh5	cadherin 5	0.079
Gab1	growth factor receptor bound protein 2-associated protein 1	0.079
Xcr1	chemokine (C motif) receptor 1	0.079
Mefv	Mediterranean fever	0.079
Skil	SKI-like	0.079
Capn2	calpain 2	0.078
Cd6	CD6 antigen	0.078
Grin2a	glutamate receptor, ionotropic, NMDA2A (epsilon 1)	0.078
Mdm2	transformed mouse 3T3 cell double minute 2	0.078
Lag3	lymphocyte-activation gene 3	0.078
Fndc7	fibronectin type III domain containing 7	0.077
Gpr132	G protein-coupled receptor 132	0.077
Ccl3	chemokine (C-C motif) ligand 3	0.077	Human
H2-Eb1	histocompatibility 2, class II antigen E beta	0.077
Rgs12	regulator of G-protein signaling 12	0.077
Wnt10a	wingless related MMTV integration site 10a	0.077
Adora2a	adenosine A2a receptor	0.076
Ets1	E26 avian leukemia oncogene 1, 5' domain	0.076
Bmp2	bone morphogenetic protein 2	0.076	Human Mouse
Ptgfrn	prostaglandin F2 receptor negative regulator	0.076
Myd88	myeloid differentiation primary response gene 88	0.075
Itga6	integrin alpha 6	0.075	Mouse
Ptgs1	prostaglandin-endoperoxide synthase 1	0.075
Acpp	acid phosphatase, prostate	0.075
Fut1	fucosyltransferase 1	0.075
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.075
Npy2r	neuropeptide Y receptor Y2	0.075
Il6st	interleukin 6 signal transducer	0.074
Drd1a	dopamine receptor D1A	0.074	Mouse
Cntn4	contactin 4	0.074
Foxf1a	forkhead box F1a	0.073
Gdf1	growth differentiation factor 1	0.073	Mouse
Aoah	acyloxyacyl hydrolase	0.073
Tead4	TEA domain family member 4	0.073
Prdm1	PR domain containing 1, with ZNF domain	0.072
Hrh2	histamine receptor H2	0.072	Mouse
Abcg1	ATP-binding cassette, sub-family G (WHITE), member 1	0.072
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.072
Npc1	Niemann Pick type C1	0.072
Irf8	interferon regulatory factor 8	0.072
Grn	granulin	0.072
Ctsk	cathepsin K	0.072
Inhba	inhibin beta-A	0.071
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.071
Cotl1	coactosin-like 1 (Dictyostelium)	0.071
Spry2	sprouty homolog 2 (Drosophila)	0.071
Ube3a	ubiquitin protein ligase E3A	0.070
Fgfr1	fibroblast growth factor receptor 1	0.070	Mouse
Ly86	lymphocyte antigen 86	0.070
Pkd2	polycystic kidney disease 2	0.069
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.069
Gif	gastric intrinsic factor	0.069
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.069
Shc3	src homology 2 domain-containing transforming protein C3	0.068
Tbx2	T-box 2	0.068
H2-Aa	histocompatibility 2, class II antigen A, alpha	0.068
Atxn7l3	ataxin 7-like 3	0.068
Slc15a3	solute carrier family 15, member 3	0.067
Fut7	fucosyltransferase 7	0.067
Mobp	myelin-associated oligodendrocytic basic protein	0.067
Cdh8	cadherin 8	0.067
Polr2d	polymerase (RNA) II (DNA directed) polypeptide D	0.067
Akap12	A kinase (PRKA) anchor protein (gravin) 12	0.067
Pspn	persephin	0.067
Pcsk1	proprotein convertase subtilisin/kexin type 1	0.066
Hck	hemopoietic cell kinase	0.066	Mouse
Lyz1	lysozyme 1	0.066
Pdpk1	3-phosphoinositide dependent protein kinase 1	0.066
Pou2af1	POU domain, class 2, associating factor 1	0.065
Nfib	nuclear factor I/B	0.065
Snai1	snail homolog 1 (Drosophila)	0.065
Wisp2	WNT1 inducible signaling pathway protein 2	0.065
Foxi3	forkhead box I3	0.064
Rb1	retinoblastoma 1	0.064
Ifnar1	interferon (alpha and beta) receptor 1	0.064
Pea15a	phosphoprotein enriched in astrocytes 15A	0.064
Cga	glycoprotein hormones, alpha subunit	0.064
Pax7	paired box gene 7	0.064
Kcnj9	potassium inwardly-rectifying channel, subfamily J, member 9	0.063
Cdh16	cadherin 16	0.063
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.063
Epb4.9	erythrocyte protein band 4.9	0.063
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.063
Myo1g	myosin IG	0.063
Hmha1	histocompatibility (minor) HA-1	0.063
Clnk	cytokine-dependent hematopoietic cell linker	0.062
Epas1	endothelial PAS domain protein 1	0.062
Il6	interleukin 6	0.062
Crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.062
Wt1	Wilms tumor 1 homolog	0.062
Aim2	absent in melanoma 2	0.061
Fpr-rs4	formyl peptide receptor, related sequence 4	0.061
Ache	acetylcholinesterase	0.061
Lyst	lysosomal trafficking regulator	0.061
Tnfaip1	tumor necrosis factor, alpha-induced protein 1 (endothelial)	0.061
Arid4a	AT rich interactive domain 4A (RBP1-like)	0.061
Osmr	oncostatin M receptor	0.061
Hgf	hepatocyte growth factor	0.061
Tinagl1	tubulointerstitial nephritis antigen-like 1	0.061
Adra2c	adrenergic receptor, alpha 2c	0.061	Mouse
BC013712	cDNA sequence BC013712	0.060
Pld4	phospholipase D family, member 4	0.060
Vat1	vesicle amine transport protein 1 homolog (T californica)	0.060
Klk6	kallikrein related-peptidase 6	0.060
Apaf1	apoptotic peptidase activating factor 1	0.059
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.059	Fly
Otp	orthopedia homolog (Drosophila)	0.059
Syt7	synaptotagmin VII	0.059
Clcnka	chloride channel Ka	0.059
Ids	iduronate 2-sulfatase	0.059
Map2k1	mitogen-activated protein kinase kinase 1	0.059	Fly
Sipa1	signal-induced proliferation associated gene 1	0.059
Tnfrsf8	tumor necrosis factor receptor superfamily, member 8	0.059
Camk4	calcium/calmodulin-dependent protein kinase IV	0.058
Adm	adrenomedullin	0.058
Pds5a	PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)	0.058
Ern2	endoplasmic reticulum (ER) to nucleus signalling 2	0.058
Snrpd1	small nuclear ribonucleoprotein D1	0.057
Ly6h	lymphocyte antigen 6 complex, locus H	0.057
Sstr1	somatostatin receptor 1	0.057
Cdh1	cadherin 1	0.057
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.057	Fly
Klf7	Kruppel-like factor 7 (ubiquitous)	0.056
Lep	leptin	0.056
Cbr1	carbonyl reductase 1	0.056
Gucy1b3	guanylate cyclase 1, soluble, beta 3	0.056
Gata6	GATA binding protein 6	0.056
Lat	linker for activation of T cells	0.056
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.056
Mkl1	MKL (megakaryoblastic leukemia)/myocardin-like 1	0.055
Amhr2	anti-Mullerian hormone type 2 receptor	0.055
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.055
Sh3kbp1	SH3-domain kinase binding protein 1	0.055
Reg3b	regenerating islet-derived 3 beta	0.055
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.055
Smad7	MAD homolog 7 (Drosophila)	0.054
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.054
Slc12a3	solute carrier family 12, member 3	0.054
Has2	hyaluronan synthase 2	0.054
Klrc1	killer cell lectin-like receptor subfamily C, member 1	0.054
Rab3il1	RAB3A interacting protein (rabin3)-like 1	0.054
Hcls1	hematopoietic cell specific Lyn substrate 1	0.054
Gab2	growth factor receptor bound protein 2-associated protein 2	0.054
Plekho2	pleckstrin homology domain containing, family O member 2	0.054
Traf6	TNF receptor-associated factor 6	0.054
Hapln1	hyaluronan and proteoglycan link protein 1	0.054
Kcna4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.054
Ric8	resistance to inhibitors of cholinesterase 8 homolog (C. elegans)	0.054
Dok3	docking protein 3	0.053	Mouse
Lck	lymphocyte protein tyrosine kinase	0.053	Mouse
Cdc34	cell division cycle 34 homolog (S. cerevisiae)	0.053
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.053
Ptpre	protein tyrosine phosphatase, receptor type, E	0.053
Trpc5	transient receptor potential cation channel, subfamily C, member 5	0.053
Epor	erythropoietin receptor	0.053
Col12a1	collagen, type XII, alpha 1	0.053
Lrrk1	leucine-rich repeat kinase 1	0.053
Meox1	mesenchyme homeobox 1	0.053
Kcnk3	potassium channel, subfamily K, member 3	0.053
Axl	AXL receptor tyrosine kinase	0.053
Tcra	T-cell receptor alpha chain	0.052
Ceacam11	carcinoembryonic antigen-related cell adhesion molecule 11	0.052
Fgf7	fibroblast growth factor 7	0.052	Mouse
Esam	endothelial cell-specific adhesion molecule	0.052
Pcsk2	proprotein convertase subtilisin/kexin type 2	0.052
Rgs9	regulator of G-protein signaling 9	0.052
Flnb	filamin, beta	0.052
Rbl1	retinoblastoma-like 1 (p107)	0.052
Cd7	CD7 antigen	0.052
Chd2	chromodomain helicase DNA binding protein 2	0.052
Ccr7	chemokine (C-C motif) receptor 7	0.051
Cd300a	CD300A antigen	0.051
Lrp2	low density lipoprotein receptor-related protein 2	0.051
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.051
Il2rb	interleukin 2 receptor, beta chain	0.051
Sst	somatostatin	0.051
Chrm4	cholinergic receptor, muscarinic 4	0.051
Gnat1	guanine nucleotide binding protein, alpha transducing 1	0.051
Cd33	CD33 antigen	0.051
Sstr2	somatostatin receptor 2	0.050
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.050
Edn3	endothelin 3	0.050
Galnt6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6	0.050
Adra1a	adrenergic receptor, alpha 1a	0.050	Rat
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.050
L1cam	L1 cell adhesion molecule	0.050
Il7r	interleukin 7 receptor	0.050
Col4a3	collagen, type IV, alpha 3	0.050
Ext1	exostoses (multiple) 1	0.050
Hbegf	heparin-binding EGF-like growth factor	0.050
Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.049
Rasip1	Ras interacting protein 1	0.049
Alms1	Alstrom syndrome 1 homolog (human)	0.049
Atp4a	ATPase, H+/K+ exchanging, gastric, alpha polypeptide	0.049
Cd38	CD38 antigen	0.049
Spp1	secreted phosphoprotein 1	0.049
Tpm4	tropomyosin 4	0.049
Clec4n	C-type lectin domain family 4, member n	0.049
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.049
Casp1	caspase 1	0.049
Gna15	guanine nucleotide binding protein, alpha 15	0.048
Aire	autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)	0.048
Nov	nephroblastoma overexpressed gene	0.048
Kcna3	potassium voltage-gated channel, shaker-related subfamily, member 3	0.048
Slamf8	SLAM family member 8	0.048
Syt9	synaptotagmin IX	0.048
Sh3bgrl3	SH3 domain binding glutamic acid-rich protein-like 3	0.048
Shkbp1	Sh3kbp1 binding protein 1	0.048
P2ry13	purinergic receptor P2Y, G-protein coupled 13	0.048
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.048
Tlr6	toll-like receptor 6	0.048	Mouse
Actn1	actinin, alpha 1	0.048
Plek	pleckstrin	0.048
Lyl1	lymphoblastomic leukemia 1	0.048
Cd34	CD34 antigen	0.047
Cdkn1c	cyclin-dependent kinase inhibitor 1C (P57)	0.047
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.047
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.047
Sstr4	somatostatin receptor 4	0.047
Pdcd10	programmed cell death 10	0.047
Nod2	nucleotide-binding oligomerization domain containing 2	0.046
Lhx3	LIM homeobox protein 3	0.046
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.046
Fgf13	fibroblast growth factor 13	0.046	Mouse
Pikfyve	phosphoinositide kinase, FYVE finger containing	0.046
Cd28	CD28 antigen	0.046
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.046
Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.046
Elk4	ELK4, member of ETS oncogene family	0.046
Hoxd11	homeobox D11	0.046
Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.046
Col4a2	collagen, type IV, alpha 2	0.046
Syt6	synaptotagmin VI	0.046
Tll1	tolloid-like	0.045
Angpt4	angiopoietin 4	0.045
Nck1	non-catalytic region of tyrosine kinase adaptor protein 1	0.045
Gpr37	G protein-coupled receptor 37	0.045
Fermt2	fermitin family homolog 2 (Drosophila)	0.045
Rgnef	Rho-guanine nucleotide exchange factor	0.045
Avpr2	arginine vasopressin receptor 2	0.045
Cd93	CD93 antigen	0.045
Clock	circadian locomotor output cycles kaput	0.045
Rab27a	RAB27A, member RAS oncogene family	0.045
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.045
Cd68	CD68 antigen	0.045
Tpsb2	tryptase beta 2	0.045
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.045	Human
Calcrl	calcitonin receptor-like	0.045
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.045
Errfi1	ERBB receptor feedback inhibitor 1	0.045
Cd300ld	CD300 molecule-like family member d	0.044
Ppig	peptidyl-prolyl isomerase G (cyclophilin G)	0.044
Adra2a	adrenergic receptor, alpha 2a	0.044	Mouse
Tcstv1	2-cell-stage, variable group, member 1	0.044
Dusp6	dual specificity phosphatase 6	0.044	Human Rat
Atoh7	atonal homolog 7 (Drosophila)	0.044
Hand2	heart and neural crest derivatives expressed transcript 2	0.044
Tmeff2	transmembrane protein with EGF-like and two follistatin-like domains 2	0.044
Myadm	myeloid-associated differentiation marker	0.044
Hapln2	hyaluronan and proteoglycan link protein 2	0.044
Mbp	myelin basic protein	0.044
Il12b	interleukin 12b	0.044
Thbs2	thrombospondin 2	0.044
Cyth4	cytohesin 4	0.043
Agtr1a	angiotensin II receptor, type 1a	0.043
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.043
Jak3	Janus kinase 3	0.043
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.043
Gaa	glucosidase, alpha, acid	0.043
Rbp2	retinol binding protein 2, cellular	0.043
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.043
Plec	plectin	0.043
Ptafr	platelet-activating factor receptor	0.043
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.043
Fpr3	formyl peptide receptor 3	0.043
Batf2	basic leucine zipper transcription factor, ATF-like 2	0.043
Cxcr4	chemokine (C-X-C motif) receptor 4	0.042
Esr2	estrogen receptor 2 (beta)	0.042	Rat
2410004A20Rik	RIKEN cDNA 2410004A20 gene	0.042
Rgs14	regulator of G-protein signaling 14	0.042	Rat
Ch25h	cholesterol 25-hydroxylase	0.042
Myf5	myogenic factor 5	0.042
Sqstm1	sequestosome 1	0.042
Khdrbs1	KH domain containing, RNA binding, signal transduction associated 1	0.042
Spnb2	spectrin beta 2	0.042
Rbpjl	recombination signal binding protein for immunoglobulin kappa J region-like	0.042
Dctn1	dynactin 1	0.041
Nog	noggin	0.041
Epha4	Eph receptor A4	0.041
Irf6	interferon regulatory factor 6	0.041
Tcirg1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3	0.041
Cela2a	chymotrypsin-like elastase family, member 2A	0.041
Matk	megakaryocyte-associated tyrosine kinase	0.041
Accn5	amiloride-sensitive cation channel 5, intestinal	0.041
Il2	interleukin 2	0.041
Diap1	diaphanous homolog 1 (Drosophila)	0.041
Fst	follistatin	0.041
Fcgr3	Fc receptor, IgG, low affinity III	0.041
Thrb	thyroid hormone receptor beta	0.041
Id2	inhibitor of DNA binding 2	0.041
Ccr6	chemokine (C-C motif) receptor 6	0.040
Tnfrsf11b	tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)	0.040
Nostrin	nitric oxide synthase trafficker	0.040
Car5a	carbonic anhydrase 5a, mitochondrial	0.040
Gjd2	gap junction protein, delta 2	0.040
Krtap5-1	keratin associated protein 5-1	0.040
Igf1	insulin-like growth factor 1	0.040
4732456N10Rik	RIKEN cDNA 4732456N10 gene	0.040
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.040
Npas1	neuronal PAS domain protein 1	0.040
Trpc6	transient receptor potential cation channel, subfamily C, member 6	0.040
Hpca	hippocalcin	0.040
Ednrb	endothelin receptor type B	0.040
Trem3	triggering receptor expressed on myeloid cells 3	0.040
Amh	anti-Mullerian hormone	0.039
Hes1	hairy and enhancer of split 1 (Drosophila)	0.039
Pax6	paired box gene 6	0.039
Itga8	integrin alpha 8	0.039	Mouse
Lair1	leukocyte-associated Ig-like receptor 1	0.039
Sox3	SRY-box containing gene 3	0.039	Mouse
Sebox	SEBOX homeobox	0.039
Clec5a	C-type lectin domain family 5, member a	0.039
Hsd3b5	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5	0.039
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.039
Gdf3	growth differentiation factor 3	0.039	Mouse
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.039
Stat5a	signal transducer and activator of transcription 5A	0.039
Itgb2l	integrin beta 2-like	0.039
Ccar1	cell division cycle and apoptosis regulator 1	0.039
Itsn1	intersectin 1 (SH3 domain protein 1A)	0.039
Aif1	allograft inflammatory factor 1	0.039
Fgf2	fibroblast growth factor 2	0.039
Sh3bp2	SH3-domain binding protein 2	0.039
Ggta1	glycoprotein galactosyltransferase alpha 1, 3	0.039
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.038
Gcgr	glucagon receptor	0.038
Tenc1	tensin like C1 domain-containing phosphatase	0.038
Ibsp	integrin binding sialoprotein	0.038
Abcg3	ATP-binding cassette, sub-family G (WHITE), member 3	0.038
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.038
Slc16a2	solute carrier family 16 (monocarboxylic acid transporters), member 2	0.038
Slc12a4	solute carrier family 12, member 4	0.038
Hras1	Harvey rat sarcoma virus oncogene 1	0.038	Human Rat
Ebi3	Epstein-Barr virus induced gene 3	0.038
Lsp1	lymphocyte specific 1	0.038
Spib	Spi-B transcription factor (Spi-1/PU.1 related)	0.038
Grb7	growth factor receptor bound protein 7	0.038
Cldn5	claudin 5	0.038
Foxm1	forkhead box M1	0.038
Flii	flightless I homolog (Drosophila)	0.038
B4galnt2	beta-1,4-N-acetyl-galactosaminyl transferase 2	0.038
Acvr2a	activin receptor IIA	0.038
Edar	ectodysplasin-A receptor	0.038
C230081A13Rik	RIKEN cDNA C230081A13 gene	0.038
Havcr2	hepatitis A virus cellular receptor 2	0.038
P2ry6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.037	Mouse
Arhgap30	Rho GTPase activating protein 30	0.037
Clec7a	C-type lectin domain family 7, member a	0.037
Npy1r	neuropeptide Y receptor Y1	0.037
Dnm1l	dynamin 1-like	0.037
Pvr	poliovirus receptor	0.037
Gabrb2	gamma-aminobutyric acid (GABA) A receptor, subunit beta 2	0.037
Cd5	CD5 antigen	0.037
Nrgn	neurogranin	0.037
Adra1b	adrenergic receptor, alpha 1b	0.037
Nfic	nuclear factor I/C	0.037
Syt17	synaptotagmin XVII	0.037
Unc93b1	unc-93 homolog B1 (C. elegans)	0.037
Cdk5r2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.037
Adrb1	adrenergic receptor, beta 1	0.037	Mouse
Gp5	glycoprotein 5 (platelet)	0.037
Cd160	CD160 antigen	0.037
Cnn2	calponin 2	0.037
Inpp5j	inositol polyphosphate 5-phosphatase J	0.037
Abcc6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	0.037
Irs1	insulin receptor substrate 1	0.037
Plaur	plasminogen activator, urokinase receptor	0.037
Slc6a20b	solute carrier family 6 (neurotransmitter transporter), member 20B	0.037
Gpc3	glypican 3	0.037
Slc25a48	solute carrier family 25, member 48	0.037
Flot1	flotillin 1	0.037
Mc3r	melanocortin 3 receptor	0.036
Tnfaip8l2	tumor necrosis factor, alpha-induced protein 8-like 2	0.036
Ctsh	cathepsin H	0.036	Human
Mcam	melanoma cell adhesion molecule	0.036
Myh10	myosin, heavy polypeptide 10, non-muscle	0.036
Wnt5a	wingless-related MMTV integration site 5A	0.036
Igk	immunoglobulin kappa chain complex	0.036
Fadd	Fas (TNFRSF6)-associated via death domain	0.036
Prrx2	paired related homeobox 2	0.036
Cacng2	calcium channel, voltage-dependent, gamma subunit 2	0.036
Tcam1	testicular cell adhesion molecule 1	0.036
Rab25	RAB25, member RAS oncogene family	0.036
Car7	carbonic anhydrase 7	0.036
Bsn	bassoon	0.036
Sema3e	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E	0.036
Crxos1	Crx opposite strand transcript 1	0.036