IMP: Integrative Multi-species Prediction

Mus musculus

89 genes annotated in mouse

regulation of endopeptidase activity

Any process that modulates the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of endopeptidase activity"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "regulation of endopeptidase activity" (in gray)

Name	Description	Probability	Func Analog Organism
Trp53	transformation related protein 53	0.987	Zebrafish Mouse Fly
Fas	Fas (TNF receptor superfamily member 6)	0.978	Rat
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.965	Mouse Fly
Ptgs2	prostaglandin-endoperoxide synthase 2	0.954
Igh	immunoglobulin heavy chain complex	0.860
Casp1	caspase 1	0.849	Mouse Fly
Emx1	empty spiracles homolog 1 (Drosophila)	0.829
Tnf	tumor necrosis factor	0.808
Il1r1	interleukin 1 receptor, type I	0.761
Stat5a	signal transducer and activator of transcription 5A	0.752	Mouse
Emx2	empty spiracles homolog 2 (Drosophila)	0.737
Akt1	thymoma viral proto-oncogene 1	0.737
Xiap	X-linked inhibitor of apoptosis	0.735
Ephb2	Eph receptor B2	0.713	Mouse
Skil	SKI-like	0.707
Mcl1	myeloid cell leukemia sequence 1	0.639	Zebrafish Mouse
Smad3	MAD homolog 3 (Drosophila)	0.636	Human Rat
Irf9	interferon regulatory factor 9	0.623
Socs1	suppressor of cytokine signaling 1	0.604
Lepr	leptin receptor	0.595
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.591
Sfrp1	secreted frizzled-related protein 1	0.585	Mouse
Mndal	myeloid nuclear differentiation antigen like	0.583
Gbp5	guanylate binding protein 5	0.560
Drd2	dopamine receptor D2	0.559
Il10	interleukin 10	0.553	Mouse
Prf1	perforin 1 (pore forming protein)	0.546
Ptprc	protein tyrosine phosphatase, receptor type, C	0.507
Cd28	CD28 antigen	0.494
Fgg	fibrinogen gamma chain	0.474
Igf1	insulin-like growth factor 1	0.471	Rat
Rara	retinoic acid receptor, alpha	0.470
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.469
Esr1	estrogen receptor 1 (alpha)	0.457
Bcl2	B-cell leukemia/lymphoma 2	0.452	Zebrafish Mouse
Ambp	alpha 1 microglobulin/bikunin	0.433	Rat
Wnt3a	wingless-related MMTV integration site 3A	0.424
Notch2	Notch gene homolog 2 (Drosophila)	0.417
Wnt7b	wingless-related MMTV integration site 7B	0.414	Mouse
Kit	kit oncogene	0.402
Cxcl13	chemokine (C-X-C motif) ligand 13	0.400
Hspa1a	heat shock protein 1A	0.376
Rb1	retinoblastoma 1	0.363
Pax3	paired box gene 3	0.362
Lif	leukemia inhibitory factor	0.361
Serping1	serine (or cysteine) peptidase inhibitor, clade G, member 1	0.354
Trp73	transformation related protein 73	0.352	Mouse Fly
Jak2	Janus kinase 2	0.352
Ctgf	connective tissue growth factor	0.351	Mouse Rat
Tlr4	toll-like receptor 4	0.350
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.337
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.336
Itga3	integrin alpha 3	0.336
Htt	huntingtin	0.336
Prkce	protein kinase C, epsilon	0.336
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.335
Stat5b	signal transducer and activator of transcription 5B	0.329	Mouse
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.323
Psen1	presenilin 1	0.320
Msln	mesothelin	0.319
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.319
Osmr	oncostatin M receptor	0.316
Nf1	neurofibromatosis 1	0.313
Cyr61	cysteine rich protein 61	0.312
Psme1	proteasome (prosome, macropain) 28 subunit, alpha	0.310
Epha2	Eph receptor A2	0.309	Mouse
Ptpn2	protein tyrosine phosphatase, non-receptor type 2	0.292
Emp2	epithelial membrane protein 2	0.291
Sox11	SRY-box containing gene 11	0.290
Fgb	fibrinogen beta chain	0.290
Casp12	caspase 12	0.289	Mouse Fly
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.289
Tcf7	transcription factor 7, T-cell specific	0.286
Il6st	interleukin 6 signal transducer	0.286
Cd44	CD44 antigen	0.280	Human
C1ra	complement component 1, r subcomponent A	0.276
Cyld	cylindromatosis (turban tumor syndrome)	0.276
Itih1	inter-alpha trypsin inhibitor, heavy chain 1	0.275
Bnc1	basonuclin 1	0.274
Dkk3	dickkopf homolog 3 (Xenopus laevis)	0.269
Irs1	insulin receptor substrate 1	0.265
Lyz2	lysozyme 2	0.264
Acvr1	activin A receptor, type 1	0.254
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.249
Fjx1	four jointed box 1 (Drosophila)	0.248
Prlr	prolactin receptor	0.246
Sfrp2	secreted frizzled-related protein 2	0.245
Grb10	growth factor receptor bound protein 10	0.244
Ret	ret proto-oncogene	0.243	Human
Ikzf1	IKAROS family zinc finger 1	0.241
Casp8	caspase 8	0.233
Pzp	pregnancy zone protein	0.232
Numb	numb gene homolog (Drosophila)	0.230
Bcl2l1	BCL2-like 1	0.229	Zebrafish Mouse
Il2rg	interleukin 2 receptor, gamma chain	0.226
Coro1b	coronin, actin binding protein 1B	0.224
Fadd	Fas (TNFRSF6)-associated via death domain	0.221	Human
Cd151	CD151 antigen	0.220
Axl	AXL receptor tyrosine kinase	0.218
Mapk14	mitogen-activated protein kinase 14	0.211
Socs3	suppressor of cytokine signaling 3	0.210
Htra3	HtrA serine peptidase 3	0.207	Fly
Otx1	orthodenticle homolog 1 (Drosophila)	0.207
Rag2	recombination activating gene 2	0.207
Ctnnb1	catenin (cadherin associated protein), beta 1	0.206
Barx1	BarH-like homeobox 1	0.204
Ikbkb	inhibitor of kappaB kinase beta	0.202
Ngf	nerve growth factor	0.202
F3	coagulation factor III	0.202	Human
Ccr1	chemokine (C-C motif) receptor 1	0.201
Vhl	von Hippel-Lindau tumor suppressor	0.201
Psme2	proteasome (prosome, macropain) 28 subunit, beta	0.200
Hpx	hemopexin	0.199
Apoa1	apolipoprotein A-I	0.198
Itih4	inter alpha-trypsin inhibitor, heavy chain 4	0.197
Cxcr5	chemokine (C-X-C motif) receptor 5	0.196
Epha4	Eph receptor A4	0.195	Mouse
Hhat	hedgehog acyltransferase	0.194
Gdnf	glial cell line derived neurotrophic factor	0.192
Mdm4	transformed mouse 3T3 cell double minute 4	0.190
E2f1	E2F transcription factor 1	0.190
Serpina1c	serine (or cysteine) peptidase inhibitor, clade A, member 1C	0.184	Human Mouse Rat
Nos2	nitric oxide synthase 2, inducible	0.184
Tgfb1	transforming growth factor, beta 1	0.184
Cfh	complement component factor h	0.183
Fga	fibrinogen alpha chain	0.179
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.176
Sardh	sarcosine dehydrogenase	0.176
Thbs1	thrombospondin 1	0.175	Human
Ldb3	LIM domain binding 3	0.175
Apoe	apolipoprotein E	0.174
Lhx1	LIM homeobox protein 1	0.173
Casp7	caspase 7	0.172	Mouse
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.171
Il2	interleukin 2	0.170
Zeb1	zinc finger E-box binding homeobox 1	0.170
Irf1	interferon regulatory factor 1	0.170
Itga1	integrin alpha 1	0.169
Efnb2	ephrin B2	0.169
Kng1	kininogen 1	0.168	Human
Pycard	PYD and CARD domain containing	0.168
Apc2	adenomatosis polyposis coli 2	0.168
Wnt6	wingless-related MMTV integration site 6	0.167	Mouse
Dab1	disabled homolog 1 (Drosophila)	0.166
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.165
Cd40	CD40 antigen	0.163
Mnda	myeloid cell nuclear differentiation antigen	0.163	Human Mouse
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.163	Mouse
Fzd8	frizzled homolog 8 (Drosophila)	0.162
Vdr	vitamin D receptor	0.161
Cdh3	cadherin 3	0.161	Mouse
Vangl2	vang-like 2 (van gogh, Drosophila)	0.161
Apom	apolipoprotein M	0.160
Krtdap	keratinocyte differentiation associated protein	0.158
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.158
Tcf3	transcription factor 3	0.156
Spry4	sprouty homolog 4 (Drosophila)	0.156
Gsn	gelsolin	0.156	Mouse
Wwtr1	WW domain containing transcription regulator 1	0.155
Cst3	cystatin C	0.155	Human
Acpp	acid phosphatase, prostate	0.154
Cenpj	centromere protein J	0.152
C2	complement component 2 (within H-2S)	0.152
Egfr	epidermal growth factor receptor	0.150
Onecut1	one cut domain, family member 1	0.148
Plxna1	plexin A1	0.148
Serpinb9	serine (or cysteine) peptidase inhibitor, clade B, member 9	0.147
Ar	androgen receptor	0.147
Ifng	interferon gamma	0.146
Sox2	SRY-box containing gene 2	0.145	Human
Psap	prosaposin	0.145
Inpp5d	inositol polyphosphate-5-phosphatase D	0.144
Rbl1	retinoblastoma-like 1 (p107)	0.143
Slc6a12	solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12	0.142
Anxa4	annexin A4	0.141
Pou3f1	POU domain, class 3, transcription factor 1	0.139
Nodal	nodal	0.138
Mfn2	mitofusin 2	0.138
Krt14	keratin 14	0.138
S100a3	S100 calcium binding protein A3	0.137
Cycs	cytochrome c, somatic	0.137
Hspb1	heat shock protein 1	0.137	Mouse
Mmp9	matrix metallopeptidase 9	0.135
Ch25h	cholesterol 25-hydroxylase	0.130
Cryab	crystallin, alpha B	0.130
Runx1	runt related transcription factor 1	0.129
Gli3	GLI-Kruppel family member GLI3	0.128
Gata6	GATA binding protein 6	0.128
Fgf10	fibroblast growth factor 10	0.128
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.127
Asprv1	aspartic peptidase, retroviral-like 1	0.127
Eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2	0.127
Cp	ceruloplasmin	0.125
Fzd1	frizzled homolog 1 (Drosophila)	0.125
Nphp4	nephronophthisis 4 (juvenile) homolog (human)	0.124
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.123
Plxna3	plexin A3	0.122
Arvcf	armadillo repeat gene deleted in velo-cardio-facial syndrome	0.121
Cdx2	caudal type homeobox 2	0.120
Alb	albumin	0.120
Anxa5	annexin A5	0.119
Ednra	endothelin receptor type A	0.119
Igbp1	immunoglobulin (CD79A) binding protein 1	0.117
Cish	cytokine inducible SH2-containing protein	0.116
Efs	embryonal Fyn-associated substrate	0.116
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.115
Tyro3	TYRO3 protein tyrosine kinase 3	0.114
Card11	caspase recruitment domain family, member 11	0.114
Csf1	colony stimulating factor 1 (macrophage)	0.112
Chd7	chromodomain helicase DNA binding protein 7	0.112
Pdgfa	platelet derived growth factor, alpha	0.111
Foxd3	forkhead box D3	0.111
Zfp651	zinc finger protein 651	0.111
Cfi	complement component factor i	0.111
Amotl2	angiomotin-like 2	0.110
Tnfrsf11b	tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)	0.110
Serpina1b	serine (or cysteine) preptidase inhibitor, clade A, member 1B	0.110
Hspe1	heat shock protein 1 (chaperonin 10)	0.109
Ikbkg	inhibitor of kappaB kinase gamma	0.109
Timp1	tissue inhibitor of metalloproteinase 1	0.108	Human Mouse Fly
Steap4	STEAP family member 4	0.108
Rxra	retinoid X receptor alpha	0.108
Adam17	a disintegrin and metallopeptidase domain 17	0.107
Plg	plasminogen	0.107
Krt36	keratin 36	0.106
Sfrp4	secreted frizzled-related protein 4	0.106
Serpind1	serine (or cysteine) peptidase inhibitor, clade D, member 1	0.105	Fly
Robo2	roundabout homolog 2 (Drosophila)	0.103
Ms4a4d	membrane-spanning 4-domains, subfamily A, member 4D	0.102
Nlrp3	NLR family, pyrin domain containing 3	0.102
Cnr1	cannabinoid receptor 1 (brain)	0.102
Wnt10b	wingless related MMTV integration site 10b	0.102	Mouse
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.101
Wnt4	wingless-related MMTV integration site 4	0.100	Mouse
Dhh	desert hedgehog	0.100
Serpina1e	serine (or cysteine) peptidase inhibitor, clade A, member 1E	0.099	Human Mouse Rat
Mitf	microphthalmia-associated transcription factor	0.099
Met	met proto-oncogene	0.098
Anxa1	annexin A1	0.098
Timm23	translocase of inner mitochondrial membrane 23 homolog (yeast)	0.097
Lcn2	lipocalin 2	0.096
Ripk3	receptor-interacting serine-threonine kinase 3	0.096
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.096
Ptch2	patched homolog 2	0.096
Gc	group specific component	0.095
Rapsn	receptor-associated protein of the synapse	0.095
Psmc2	proteasome (prosome, macropain) 26S subunit, ATPase 2	0.095
Mapk3	mitogen-activated protein kinase 3	0.094
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.094
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.094
Npm1	nucleophosmin 1	0.094
Serpinb6c	serine (or cysteine) peptidase inhibitor, clade B, member 6c	0.094	Human Mouse
Gas1	growth arrest specific 1	0.093
Thbs2	thrombospondin 2	0.093
F2	coagulation factor II	0.093
Serpinf2	serine (or cysteine) peptidase inhibitor, clade F, member 2	0.092	Human Mouse Rat
Pcsk6	proprotein convertase subtilisin/kexin type 6	0.091
Gjb5	gap junction protein, beta 5	0.091
C1s	complement component 1, s subcomponent	0.091
Fgf7	fibroblast growth factor 7	0.091
Dnase1l2	deoxyribonuclease 1-like 2	0.091
Hp	haptoglobin	0.090
Serpinb5	serine (or cysteine) peptidase inhibitor, clade B, member 5	0.090	Mouse
Trim21	tripartite motif-containing 21	0.090
Hsd17b2	hydroxysteroid (17-beta) dehydrogenase 2	0.089
A2m	alpha-2-macroglobulin	0.089	Human Rat
Serpina3c	serine (or cysteine) peptidase inhibitor, clade A, member 3C	0.089	Mouse
Fosl2	fos-like antigen 2	0.088
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.088
Pstpip1	proline-serine-threonine phosphatase-interacting protein 1	0.088
Tm4sf1	transmembrane 4 superfamily member 1	0.088
Add1	adducin 1 (alpha)	0.088
Serpina10	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.088	Fly
Apoa2	apolipoprotein A-II	0.088
Lama1	laminin, alpha 1	0.087
Pdx1	pancreatic and duodenal homeobox 1	0.087
Il7	interleukin 7	0.086
Irf6	interferon regulatory factor 6	0.086
Pthlh	parathyroid hormone-like peptide	0.085
Il22	interleukin 22	0.085	Mouse
Nog	noggin	0.085
Arx	aristaless related homeobox	0.085
Igf2	insulin-like growth factor 2	0.084
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.084
Pkp1	plakophilin 1	0.084
L1cam	L1 cell adhesion molecule	0.084
Fzd4	frizzled homolog 4 (Drosophila)	0.084
Npy1r	neuropeptide Y receptor Y1	0.083
Casp3	caspase 3	0.083	Mouse
Hbegf	heparin-binding EGF-like growth factor	0.083
Cdkn2d	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	0.083	Human
F12	coagulation factor XII (Hageman factor)	0.083
Trp63	transformation related protein 63	0.083
Lama5	laminin, alpha 5	0.083	Worm
Stc2	stanniocalcin 2	0.082
Prnp	prion protein	0.082
Lyst	lysosomal trafficking regulator	0.081
Cpz	carboxypeptidase Z	0.081
Sema3b	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	0.081
Pmp22	peripheral myelin protein 22	0.080
Sema3c	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	0.080
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.080
Anxa7	annexin A7	0.080
Cmah	cytidine monophospho-N-acetylneuraminic acid hydroxylase	0.080
Hoxb4	homeobox B4	0.080
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.079
Fgfbp1	fibroblast growth factor binding protein 1	0.079
Il2rb	interleukin 2 receptor, beta chain	0.078
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.078
Hnf4a	hepatic nuclear factor 4, alpha	0.078
Prm2	protamine 2	0.078
Pld2	phospholipase D2	0.078
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.078
Efna4	ephrin A4	0.078
Apaf1	apoptotic peptidase activating factor 1	0.078
Ywhaq	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.078
S100a10	S100 calcium binding protein A10 (calpactin)	0.078
Msn	moesin	0.077
Ilk	integrin linked kinase	0.077
Hes5	hairy and enhancer of split 5 (Drosophila)	0.077
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.077
Pgr	progesterone receptor	0.077
Nphs2	nephrosis 2 homolog, podocin (human)	0.076
Pofut1	protein O-fucosyltransferase 1	0.076
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.076
Vav2	vav 2 oncogene	0.076
Birc3	baculoviral IAP repeat-containing 3	0.076	Mouse
Cd9	CD9 antigen	0.075
Capn1	calpain 1	0.075
Esr2	estrogen receptor 2 (beta)	0.075
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.074
Gpr50	G-protein-coupled receptor 50	0.074
Ly96	lymphocyte antigen 96	0.074
C3	complement component 3	0.074	Mouse
Slc46a2	solute carrier family 46, member 2	0.074
Tbk1	TANK-binding kinase 1	0.074	Fly
Il4ra	interleukin 4 receptor, alpha	0.073
Daxx	Fas death domain-associated protein	0.073
Ephb3	Eph receptor B3	0.072	Mouse
Aim2	absent in melanoma 2	0.072
Camk2d	calcium/calmodulin-dependent protein kinase II, delta	0.072
Icos	inducible T-cell co-stimulator	0.072
Akt2	thymoma viral proto-oncogene 2	0.072	Mouse Rat
F10	coagulation factor X	0.072
Bcl2l10	Bcl2-like 10	0.071
Tnc	tenascin C	0.071
Mfap5	microfibrillar associated protein 5	0.070
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.070
Lamc2	laminin, gamma 2	0.070
Uba7	ubiquitin-like modifier activating enzyme 7	0.070
Ep300	E1A binding protein p300	0.070
H2-Q10	histocompatibility 2, Q region locus 10	0.070
Lbp	lipopolysaccharide binding protein	0.070
Cs	citrate synthase	0.070
Gfpt2	glutamine fructose-6-phosphate transaminase 2	0.069
Tspan32	tetraspanin 32	0.069
Serpina1a	serine (or cysteine) peptidase inhibitor, clade A, member 1A	0.069	Human Mouse Rat
Inhbb	inhibin beta-B	0.069
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.069
Prl4a1	prolactin family 4, subfamily a, member 1	0.069
Itch	itchy, E3 ubiquitin protein ligase	0.069
Fgfr1	fibroblast growth factor receptor 1	0.069
Rnf41	ring finger protein 41	0.068
Apcs	serum amyloid P-component	0.068
Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.068
Hist1h1t	histone cluster 1, H1t	0.068
C4b	complement component 4B (Childo blood group)	0.068	Mouse
Mt4	metallothionein 4	0.068
Psmb10	proteasome (prosome, macropain) subunit, beta type 10	0.068
Fasl	Fas ligand (TNF superfamily, member 6)	0.068	Human Mouse
1100001G20Rik	RIKEN cDNA 1100001G20 gene	0.067
Gm10393	predicted gene 10393	0.067
Krt13	keratin 13	0.067
Pdgfb	platelet derived growth factor, B polypeptide	0.067
Hap1	huntingtin-associated protein 1	0.067
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.067
Mybph	myosin binding protein H	0.067
Apof	apolipoprotein F	0.067
Itgb4	integrin beta 4	0.066
Ceacam16	carcinoembryonic antigen-related cell adhesion molecule 16	0.066
F2r	coagulation factor II (thrombin) receptor	0.066	Human
Fbln2	fibulin 2	0.066
Dclre1c	DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)	0.066
Pml	promyelocytic leukemia	0.065
Hoxc9	homeobox C9	0.065
Otx2	orthodenticle homolog 2 (Drosophila)	0.065
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.065
Fgf2	fibroblast growth factor 2	0.065
Ptgfrn	prostaglandin F2 receptor negative regulator	0.065
Timp2	tissue inhibitor of metalloproteinase 2	0.065
Mgp	matrix Gla protein	0.065
Dcn	decorin	0.065
Mdm2	transformed mouse 3T3 cell double minute 2	0.065
Gpc3	glypican 3	0.064
Tpbg	trophoblast glycoprotein	0.064
Huwe1	HECT, UBA and WWE domain containing 1	0.064
Irs3	insulin receptor substrate 3	0.064
Emid2	EMI domain containing 2	0.064
Crhr1	corticotropin releasing hormone receptor 1	0.064
C1qtnf1	C1q and tumor necrosis factor related protein 1	0.063
Nmi	N-myc (and STAT) interactor	0.063
Pla2g4f	phospholipase A2, group IVF	0.063
Rnase1	ribonuclease, RNase A family, 1 (pancreatic)	0.063
Plxna4	plexin A4	0.063
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.063
Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	0.063	Mouse
Src	Rous sarcoma oncogene	0.063	Human
Gjb3	gap junction protein, beta 3	0.063
Tnfaip6	tumor necrosis factor alpha induced protein 6	0.063
Clip2	CAP-GLY domain containing linker protein 2	0.062
Fkbp3	FK506 binding protein 3	0.062
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.062	Mouse
Csk	c-src tyrosine kinase	0.062
Gcsh	glycine cleavage system protein H (aminomethyl carrier)	0.062
Hccs	holocytochrome c synthetase	0.062
Errfi1	ERBB receptor feedback inhibitor 1	0.062
Wwox	WW domain-containing oxidoreductase	0.062
Crygd	crystallin, gamma D	0.062
Mmp17	matrix metallopeptidase 17	0.062
Set	SET nuclear oncogene	0.061
Hoxa10	homeobox A10	0.061
Fndc1	fibronectin type III domain containing 1	0.061
Timp3	tissue inhibitor of metalloproteinase 3	0.061	Mouse Fly
Saa2	serum amyloid A 2	0.061
St3gal1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	0.061
Cd81	CD81 antigen	0.061
AW112010	expressed sequence AW112010	0.061
H2-M3	histocompatibility 2, M region locus 3	0.061
Procr	protein C receptor, endothelial	0.061
Irs2	insulin receptor substrate 2	0.061
Odz4	odd Oz/ten-m homolog 4 (Drosophila)	0.061
Gbp2	guanylate binding protein 2	0.061
Fgf18	fibroblast growth factor 18	0.060
Hnf1a	HNF1 homeobox A	0.060
Ubc	ubiquitin C	0.060
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.060
Blvra	biliverdin reductase A	0.060
Igf2r	insulin-like growth factor 2 receptor	0.060
Mpzl2	myelin protein zero-like 2	0.060
Foxn1	forkhead box N1	0.060
Nrp1	neuropilin 1	0.060
Nos1	nitric oxide synthase 1, neuronal	0.060
Ooep	oocyte expressed protein homolog (dog)	0.060
Gnmt	glycine N-methyltransferase	0.060
Sp100	nuclear antigen Sp100	0.059
Apoa5	apolipoprotein A-V	0.059
Sqstm1	sequestosome 1	0.059
Hivep2	human immunodeficiency virus type I enhancer binding protein 2	0.059
Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.058
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.058
Rel	reticuloendotheliosis oncogene	0.058
Bbc3	BCL2 binding component 3	0.058
Hspa8	heat shock protein 8	0.058
Bag3	BCL2-associated athanogene 3	0.058
Maff	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)	0.058
Wfdc12	WAP four-disulfide core domain 12	0.057
Mapk8	mitogen-activated protein kinase 8	0.057
Hif1a	hypoxia inducible factor 1, alpha subunit	0.057
Sav1	salvador homolog 1 (Drosophila)	0.057
Bmp1	bone morphogenetic protein 1	0.057
Itgal	integrin alpha L	0.057
C9	complement component 9	0.057
Mib1	mindbomb homolog 1 (Drosophila)	0.056
Itih3	inter-alpha trypsin inhibitor, heavy chain 3	0.056
Crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.056
Hspb8	heat shock protein 8	0.055	Mouse
Apc	adenomatosis polyposis coli	0.055
P2rx2	purinergic receptor P2X, ligand-gated ion channel, 2	0.055	Mouse
Lef1	lymphoid enhancer binding factor 1	0.055	Human
Tcp11	t-complex protein 11	0.055
Traf1	TNF receptor-associated factor 1	0.055
Cyp11b1	cytochrome P450, family 11, subfamily b, polypeptide 1	0.055
Dmgdh	dimethylglycine dehydrogenase precursor	0.055
Ptges3	prostaglandin E synthase 3 (cytosolic)	0.055
Mapk1	mitogen-activated protein kinase 1	0.055
Il18	interleukin 18	0.055
Aplp2	amyloid beta (A4) precursor-like protein 2	0.055
Fhl1	four and a half LIM domains 1	0.055
Lag3	lymphocyte-activation gene 3	0.055
Tcof1	Treacher Collins Franceschetti syndrome 1, homolog	0.054
Fuz	fuzzy homolog (Drosophila)	0.054
Ctnna2	catenin (cadherin associated protein), alpha 2	0.054
Ahnak	AHNAK nucleoprotein (desmoyokin)	0.054
Cldn4	claudin 4	0.054
Ifi204	interferon activated gene 204	0.054	Human Mouse
Zic3	zinc finger protein of the cerebellum 3	0.054
Serpina3m	serine (or cysteine) peptidase inhibitor, clade A, member 3M	0.054	Mouse
Timm22	translocase of inner mitochondrial membrane 22 homolog (yeast)	0.054
Bax	BCL2-associated X protein	0.054
Tmprss11e	transmembrane protease, serine 11e	0.054
Sgcd	sarcoglycan, delta (dystrophin-associated glycoprotein)	0.054
Syt9	synaptotagmin IX	0.054
Spry2	sprouty homolog 2 (Drosophila)	0.054
Fgfr2	fibroblast growth factor receptor 2	0.054
Cd47	CD47 antigen (Rh-related antigen, integrin-associated signal transducer)	0.053
Proc	protein C	0.053
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.053
Foxf1a	forkhead box F1a	0.053
Vdac2	voltage-dependent anion channel 2	0.053
Cyp24a1	cytochrome P450, family 24, subfamily a, polypeptide 1	0.053
Nbl1	neuroblastoma, suppression of tumorigenicity 1	0.053
Anxa3	annexin A3	0.053
Dll1	delta-like 1 (Drosophila)	0.053
Nppb	natriuretic peptide type B	0.053
Zfp36	zinc finger protein 36	0.052
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.052
Matn2	matrilin 2	0.052
Sod2	superoxide dismutase 2, mitochondrial	0.052
Ppl	periplakin	0.052
Cbx2	chromobox homolog 2 (Drosophila Pc class)	0.052
Wt1	Wilms tumor 1 homolog	0.052
C1rb	complement component 1, r subcomponent B	0.052
Lgals7	lectin, galactose binding, soluble 7	0.052
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.052
Ctsk	cathepsin K	0.052
Car12	carbonic anyhydrase 12	0.052
Qsox1	quiescin Q6 sulfhydryl oxidase 1	0.052
Aff1	AF4/FMR2 family, member 1	0.052
Nnmt	nicotinamide N-methyltransferase	0.052
Vim	vimentin	0.052
Loxl2	lysyl oxidase-like 2	0.052
Rgnef	Rho-guanine nucleotide exchange factor	0.051
Stfa3	stefin A3	0.051	Human Mouse
Klf6	Kruppel-like factor 6	0.051
Dtx1	deltex 1 homolog (Drosophila)	0.051
Vwa5a	von Willebrand factor A domain containing 5A	0.051
Cfb	complement factor B	0.050
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.050
Mov10	Moloney leukemia virus 10	0.050
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.050
Map1lc3b	microtubule-associated protein 1 light chain 3 beta	0.050
Krt19	keratin 19	0.050
Zap70	zeta-chain (TCR) associated protein kinase	0.050
Map4k1	mitogen-activated protein kinase kinase kinase kinase 1	0.050
Klk6	kallikrein related-peptidase 6	0.050
Sox5	SRY-box containing gene 5	0.050
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.050
Azgp1	alpha-2-glycoprotein 1, zinc	0.049
Stat4	signal transducer and activator of transcription 4	0.049	Mouse
Kcnd3	potassium voltage-gated channel, Shal-related family, member 3	0.049
Jun	Jun oncogene	0.049
Cyp1b1	cytochrome P450, family 1, subfamily b, polypeptide 1	0.049
Orm1	orosomucoid 1	0.049
Dusp1	dual specificity phosphatase 1	0.049
Tcra	T-cell receptor alpha chain	0.049
Apoc4	apolipoprotein C-IV	0.048
Ren1	renin 1 structural	0.048
Masp1	mannan-binding lectin serine peptidase 1	0.048
Slit2	slit homolog 2 (Drosophila)	0.048
Fam84a	family with sequence similarity 84, member A	0.048
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.048
Cldn1	claudin 1	0.048
Adra2c	adrenergic receptor, alpha 2c	0.048
Ptk2	PTK2 protein tyrosine kinase 2	0.048
Fstl3	follistatin-like 3	0.048
Nrg3	neuregulin 3	0.048
Ltb	lymphotoxin B	0.048
Sva	seminal vesicle antigen	0.047
Apoc2	apolipoprotein C-II	0.047
Gcnt2	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme	0.047
Ankfy1	ankyrin repeat and FYVE domain containing 1	0.047
Fos	FBJ osteosarcoma oncogene	0.047
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.047
Amh	anti-Mullerian hormone	0.047
Il15	interleukin 15	0.047
Gpr87	G protein-coupled receptor 87	0.047
Ctrb1	chymotrypsinogen B1	0.047
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.047
Capn2	calpain 2	0.047
Adrb1	adrenergic receptor, beta 1	0.047
Arid5b	AT rich interactive domain 5B (MRF1-like)	0.047
Nf2	neurofibromatosis 2	0.047
Ccdc80	coiled-coil domain containing 80	0.047
Ccl7	chemokine (C-C motif) ligand 7	0.047
Slit3	slit homolog 3 (Drosophila)	0.047
Gbp7	guanylate binding protein 7	0.046
H2-Bl	histocompatibility 2, blastocyst	0.046
Mapt	microtubule-associated protein tau	0.046
Rnf115	ring finger protein 115	0.046
Ankrd1	ankyrin repeat domain 1 (cardiac muscle)	0.046
Tcrd	T-cell receptor delta chain	0.046
Hrg	histidine-rich glycoprotein	0.046
Tfrc	transferrin receptor	0.046
Psma6	proteasome (prosome, macropain) subunit, alpha type 6	0.046
Isl1	ISL1 transcription factor, LIM/homeodomain	0.046
Gbp3	guanylate binding protein 3	0.046
Kitl	kit ligand	0.046
Mug1	murinoglobulin 1	0.046	Mouse
Pdlim3	PDZ and LIM domain 3	0.046
Itgb3	integrin beta 3	0.046
Ifngr1	interferon gamma receptor 1	0.046
Hspb7	heat shock protein family, member 7 (cardiovascular)	0.046
Col8a1	collagen, type VIII, alpha 1	0.046
Gtf2ird1	general transcription factor II I repeat domain-containing 1	0.046
Hoxa11	homeobox A11	0.046
Myo1e	myosin IE	0.046
Ucn2	urocortin 2	0.046
Pou3f3	POU domain, class 3, transcription factor 3	0.046
Dsg2	desmoglein 2	0.046
Stat1	signal transducer and activator of transcription 1	0.046
Cd5	CD5 antigen	0.045
Sat1	spermidine/spermine N1-acetyl transferase 1	0.045
Lrp5	low density lipoprotein receptor-related protein 5	0.045
Ptk2b	PTK2 protein tyrosine kinase 2 beta	0.045
Lox	lysyl oxidase	0.045
Gucy1b3	guanylate cyclase 1, soluble, beta 3	0.045
Cyp2c50	cytochrome P450, family 2, subfamily c, polypeptide 50	0.045
Igfbp2	insulin-like growth factor binding protein 2	0.045
Slurp1	secreted Ly6/Plaur domain containing 1	0.045
Chst2	carbohydrate sulfotransferase 2	0.045
Ifnar1	interferon (alpha and beta) receptor 1	0.045
Cd38	CD38 antigen	0.045
Clic1	chloride intracellular channel 1	0.045
Sycn	syncollin	0.045
Orm2	orosomucoid 2	0.044
Sox10	SRY-box containing gene 10	0.044
Fam20c	family with sequence similarity 20, member C	0.044
Azi2	5-azacytidine induced gene 2	0.044
Hspa9	heat shock protein 9	0.044
Sod3	superoxide dismutase 3, extracellular	0.044
Prkcb	protein kinase C, beta	0.044
Pvrl1	poliovirus receptor-related 1	0.044
Abcc6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	0.044
Il6	interleukin 6	0.044
Ltbp1	latent transforming growth factor beta binding protein 1	0.044
Ddr2	discoidin domain receptor family, member 2	0.044
Klkb1	kallikrein B, plasma 1	0.044
Stx4a	syntaxin 4A (placental)	0.044
Agxt	alanine-glyoxylate aminotransferase	0.044
Hoxd11	homeobox D11	0.044
Rhob	ras homolog gene family, member B	0.044
Ostf1	osteoclast stimulating factor 1	0.044
Tdo2	tryptophan 2,3-dioxygenase	0.044
Clca1	chloride channel calcium activated 1	0.044
Ppara	peroxisome proliferator activated receptor alpha	0.044
Tiam1	T-cell lymphoma invasion and metastasis 1	0.044
Erf	Ets2 repressor factor	0.044
Plac8	placenta-specific 8	0.044
Ahsg	alpha-2-HS-glycoprotein	0.044	Mouse
Ptafr	platelet-activating factor receptor	0.044
Cdh1	cadherin 1	0.043
Pomp	proteasome maturation protein	0.043
Serpine2	serine (or cysteine) peptidase inhibitor, clade E, member 2	0.043
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.043
Tox	thymocyte selection-associated high mobility group box	0.043
Srebf2	sterol regulatory element binding factor 2	0.043
Nck2	non-catalytic region of tyrosine kinase adaptor protein 2	0.043
Cxadr	coxsackie virus and adenovirus receptor	0.043
Ceacam2	carcinoembryonic antigen-related cell adhesion molecule 2	0.043
Edar	ectodysplasin-A receptor	0.043
Sdc2	syndecan 2	0.043
Tpx2	TPX2, microtubule-associated protein homolog (Xenopus laevis)	0.043
Lamb1	laminin B1	0.043
Nynrin	NYN domain and retroviral integrase containing	0.043
Diablo	diablo homolog (Drosophila)	0.043
Adamts5	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)	0.043
Txndc17	thioredoxin domain containing 17	0.043
Hoxb13	homeobox B13	0.043
Smo	smoothened homolog (Drosophila)	0.043
Pax6	paired box gene 6	0.043
Fpr2	formyl peptide receptor 2	0.042
Rbp2	retinol binding protein 2, cellular	0.042
Celsr1	cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)	0.042
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.042
Cdk14	cyclin-dependent kinase 14	0.042
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.042
Fgf5	fibroblast growth factor 5	0.042
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.042
S100a16	S100 calcium binding protein A16	0.042
Mmp13	matrix metallopeptidase 13	0.042
Hoxd13	homeobox D13	0.042
Bcl6	B-cell leukemia/lymphoma 6	0.042
Id1	inhibitor of DNA binding 1	0.042
Vcan	versican	0.042
Serpina12	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12	0.042	Mouse
Wrn	Werner syndrome homolog (human)	0.042
Adrbk1	adrenergic receptor kinase, beta 1	0.042
Ly6h	lymphocyte antigen 6 complex, locus H	0.042
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.042
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.042
Map3k3	mitogen-activated protein kinase kinase kinase 3	0.041
Rnase4	ribonuclease, RNase A family 4	0.041
Flcn	folliculin	0.041
Tmbim1	transmembrane BAX inhibitor motif containing 1	0.041
Pou3f2	POU domain, class 3, transcription factor 2	0.041
Hal	histidine ammonia lyase	0.041
Stat6	signal transducer and activator of transcription 6	0.041	Mouse
Plscr1	phospholipid scramblase 1	0.041
Celsr2	cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)	0.041
Tnfsf9	tumor necrosis factor (ligand) superfamily, member 9	0.041
Mup3	major urinary protein 3	0.041
Krt4	keratin 4	0.041
Gata5	GATA binding protein 5	0.041
Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	0.041
Aip	aryl-hydrocarbon receptor-interacting protein	0.041
Efna3	ephrin A3	0.041
Fam83g	family with sequence similarity 83, member G	0.041
Cdx1	caudal type homeobox 1	0.041
Fscn1	fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)	0.041
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.041
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.041
Mysm1	myb-like, SWIRM and MPN domains 1	0.040
Saa3	serum amyloid A 3	0.040
2210010C04Rik	RIKEN cDNA 2210010C04 gene	0.040
Ate1	arginyltransferase 1	0.040
Nfil3	nuclear factor, interleukin 3, regulated	0.040
Tnfrsf12a	tumor necrosis factor receptor superfamily, member 12a	0.040
Sema3e	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E	0.040
Dsc1	desmocollin 1	0.040	Mouse
Zfp185	zinc finger protein 185	0.040
Cyp7b1	cytochrome P450, family 7, subfamily b, polypeptide 1	0.040
Becn1	beclin 1, autophagy related	0.040
Serpinb6a	serine (or cysteine) peptidase inhibitor, clade B, member 6a	0.040	Human Mouse
Gcm2	glial cells missing homolog 2 (Drosophila)	0.040
Krtap3-3	keratin associated protein 3-3	0.040
Lgals8	lectin, galactose binding, soluble 8	0.040
Vegfa	vascular endothelial growth factor A	0.040	Human
Glrx3	glutaredoxin 3	0.040
Lipc	lipase, hepatic	0.040
Kif1a	kinesin family member 1A	0.040
Bag1	BCL2-associated athanogene 1	0.040
Slc32a1	solute carrier family 32 (GABA vesicular transporter), member 1	0.040
Nr4a3	nuclear receptor subfamily 4, group A, member 3	0.040	Mouse
Tcf21	transcription factor 21	0.040
Lmna	lamin A	0.040
Il11	interleukin 11	0.040
P2rx3	purinergic receptor P2X, ligand-gated ion channel, 3	0.040	Mouse
Mpv17	MpV17 mitochondrial inner membrane protein	0.040
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.039
Tnfsf10	tumor necrosis factor (ligand) superfamily, member 10	0.039	Human Mouse
Fam46a	family with sequence similarity 46, member A	0.039
Adrb3	adrenergic receptor, beta 3	0.039
F9	coagulation factor IX	0.039
Bin1	bridging integrator 1	0.039
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.039
St8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.039
Gdf5	growth differentiation factor 5	0.039
Lap3	leucine aminopeptidase 3	0.039
Clu	clusterin	0.039
Fez2	fasciculation and elongation protein zeta 2 (zygin II)	0.039
Dennd5a	DENN/MADD domain containing 5A	0.039
Apobec3	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3	0.039
Trim62	tripartite motif-containing 62	0.039
St3gal2	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	0.039
Akr1c6	aldo-keto reductase family 1, member C6	0.039
Amhr2	anti-Mullerian hormone type 2 receptor	0.039
Lrg1	leucine-rich alpha-2-glycoprotein 1	0.039
Alpl	alkaline phosphatase, liver/bone/kidney	0.039
Id2	inhibitor of DNA binding 2	0.039
Pam	peptidylglycine alpha-amidating monooxygenase	0.039