IMP: Integrative Multi-species Prediction

Mus musculus

4 genes annotated in mouse

l ascorbic acid metabolic process

GO:0019852

The chemical reactions and pathways involving L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "l ascorbic acid metabolic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "l ascorbic acid metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Gclm	glutamate-cysteine ligase, modifier subunit	0.991
Prdx1	peroxiredoxin 1	0.359
Lamp1	lysosomal-associated membrane protein 1	0.259
Ftl1	ferritin light chain 1	0.164
Rnh1	ribonuclease/angiogenin inhibitor 1	0.108
Nphp1	nephronophthisis 1 (juvenile) homolog (human)	0.102
Atp6v0c	ATPase, H+ transporting, lysosomal V0 subunit C	0.088
Fuca1	fucosidase, alpha-L- 1, tissue	0.071
Ppib	peptidylprolyl isomerase B	0.067
Cope	coatomer protein complex, subunit epsilon	0.063
Cfi	complement component factor i	0.063
6720456B07Rik	RIKEN cDNA 6720456B07 gene	0.060
Esd	esterase D/formylglutathione hydrolase	0.059
Eef1a1	eukaryotic translation elongation factor 1 alpha 1	0.052
Atp6v0e	ATPase, H+ transporting, lysosomal V0 subunit E	0.052
Cndp2	CNDP dipeptidase 2 (metallopeptidase M20 family)	0.050
Gsta4	glutathione S-transferase, alpha 4	0.048
Gabarap	gamma-aminobutyric acid receptor associated protein	0.048
Clptm1l	CLPTM1-like	0.044
Coro1b	coronin, actin binding protein 1B	0.042
Lepr	leptin receptor	0.041
Ergic3	ERGIC and golgi 3	0.040
Agtr1a	angiotensin II receptor, type 1a	0.040
Stk39	serine/threonine kinase 39, STE20/SPS1 homolog (yeast)	0.039
Nme2	non-metastatic cells 2, protein (NM23B) expressed in	0.039
Rnaset2a	ribonuclease T2A	0.039
Clta	clathrin, light polypeptide (Lca)	0.038
2400001E08Rik	RIKEN cDNA 2400001E08 gene	0.036
P4hb	prolyl 4-hydroxylase, beta polypeptide	0.030
Dap	death-associated protein	0.030
Atp6v0d1	ATPase, H+ transporting, lysosomal V0 subunit D1	0.030
Ufc1	ubiquitin-fold modifier conjugating enzyme 1	0.029
Txndc17	thioredoxin domain containing 17	0.029
Cyb5	cytochrome b-5	0.029
Fth1	ferritin heavy chain 1	0.028
Alb	albumin	0.028
Bcap31	B-cell receptor-associated protein 31	0.027
Dhrs1	dehydrogenase/reductase (SDR family) member 1	0.027
Tbcb	tubulin folding cofactor B	0.027
Vps28	vacuolar protein sorting 28 (yeast)	0.025
Ctsb	cathepsin B	0.024
Cstb	cystatin B	0.024
Cldn10	claudin 10	0.023
0610031J06Rik	RIKEN cDNA 0610031J06 gene	0.023
Slc27a2	solute carrier family 27 (fatty acid transporter), member 2	0.023
Pttg1ip	pituitary tumor-transforming 1 interacting protein	0.023
Slc2a2	solute carrier family 2 (facilitated glucose transporter), member 2	0.022
Trappc3	trafficking protein particle complex 3	0.022
BC004004	cDNA sequence BC004004	0.022
Ppia	peptidylprolyl isomerase A	0.021
Gstp1	glutathione S-transferase, pi 1	0.021
Cyb5r3	cytochrome b5 reductase 3	0.021
Dscr3	Down syndrome critical region gene 3	0.021
Prdx5	peroxiredoxin 5	0.021
Lgals1	lectin, galactose binding, soluble 1	0.020
Plin2	perilipin 2	0.020
Zfp335	zinc finger protein 335	0.020
Ftl2	ferritin light chain 2	0.020
Taldo1	transaldolase 1	0.020
Vkorc1	vitamin K epoxide reductase complex, subunit 1	0.020
Mettl7b	methyltransferase like 7B	0.020
Iyd	iodotyrosine deiodinase	0.020
Apon	apolipoprotein N	0.019
Tor1a	torsin family 1, member A (torsin A)	0.019
Aadac	arylacetamide deacetylase (esterase)	0.019
Tex19.2	testis expressed gene 19.2	0.019
Slc47a1	solute carrier family 47, member 1	0.019
Copz1	coatomer protein complex, subunit zeta 1	0.019
Gyk	glycerol kinase	0.019
Rnf181	ring finger protein 181	0.018
Upb1	ureidopropionase, beta	0.017
Ttc36	tetratricopeptide repeat domain 36	0.017
Slc19a2	solute carrier family 19 (thiamine transporter), member 2	0.017
Nagk	N-acetylglucosamine kinase	0.017
Snx3	sorting nexin 3	0.017
Cd81	CD81 antigen	0.017
Tmem111	transmembrane protein 111	0.016
Fgl1	fibrinogen-like protein 1	0.016
Cnih	cornichon homolog (Drosophila)	0.016
Pga5	pepsinogen 5, group I	0.016
Mcfd2	multiple coagulation factor deficiency 2	0.016
Prdx6	peroxiredoxin 6	0.016
Rsc1a1	regulatory solute carrier protein, family 1, member 1	0.016
Apof	apolipoprotein F	0.016
Dazap2	DAZ associated protein 2	0.016
Pcbd1	pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1	0.016
Aldob	aldolase B, fructose-bisphosphate	0.015
Cyp2c44	cytochrome P450, family 2, subfamily c, polypeptide 44	0.015
Pgk1	phosphoglycerate kinase 1	0.015
Ebp	phenylalkylamine Ca2+ antagonist (emopamil) binding protein	0.015
Lass2	LAG1 homolog, ceramide synthase 2	0.015
1810046J19Rik	RIKEN cDNA 1810046J19 gene	0.015
Tmed10	transmembrane emp24-like trafficking protein 10 (yeast)	0.015
Cdipt	CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)	0.015
Fgg	fibrinogen gamma chain	0.015
Atp6v1f	ATPase, H+ transporting, lysosomal V1 subunit F	0.014
Ctsd	cathepsin D	0.014
Sra1	steroid receptor RNA activator 1	0.014
Pdzk1	PDZ domain containing 1	0.014
Cyp4a12a	cytochrome P450, family 4, subfamily a, polypeptide 12a	0.014
Sil1	endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)	0.014
Dcxr	dicarbonyl L-xylulose reductase	0.014
Gstm6	glutathione S-transferase, mu 6	0.014
Cyp3a11	cytochrome P450, family 3, subfamily a, polypeptide 11	0.014
Krtcap2	keratinocyte associated protein 2	0.014
Slc22a1	solute carrier family 22 (organic cation transporter), member 1	0.014
Dad1	defender against cell death 1	0.013
Prelid1	PRELI domain containing 1	0.013
Pla2g12b	phospholipase A2, group XIIB	0.013
Perp	PERP, TP53 apoptosis effector	0.013
Pdcd6	programmed cell death 6	0.013
Pnp	purine-nucleoside phosphorylase	0.013
Akr1c13	aldo-keto reductase family 1, member C13	0.013
Tspan31	tetraspanin 31	0.013
Npc2	Niemann Pick type C2	0.013
Txn1	thioredoxin 1	0.013
Bri3	brain protein I3	0.013
Gsto1	glutathione S-transferase omega 1	0.013	Human Rat
9530008L14Rik	RIKEN cDNA 9530008L14 gene	0.013
Tmbim6	transmembrane BAX inhibitor motif containing 6	0.012
Slc25a13	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13	0.012
Fxyd4	FXYD domain-containing ion transport regulator 4	0.012
Sepx1	selenoprotein X 1	0.012
Pafah2	platelet-activating factor acetylhydrolase 2	0.012
Hexa	hexosaminidase A	0.012
Cox7a2l	cytochrome c oxidase subunit VIIa polypeptide 2-like	0.012
Itm2c	integral membrane protein 2C	0.012
Rnf128	ring finger protein 128	0.012
Cth	cystathionase (cystathionine gamma-lyase)	0.012
Gba	glucosidase, beta, acid	0.012
Slc25a33	solute carrier family 25, member 33	0.012
Fbp1	fructose bisphosphatase 1	0.012
Txndc12	thioredoxin domain containing 12 (endoplasmic reticulum)	0.012
Hao1	hydroxyacid oxidase 1, liver	0.012
Neu3	neuraminidase 3	0.012
Atp6ap1	ATPase, H+ transporting, lysosomal accessory protein 1	0.012
Serpina1c	serine (or cysteine) peptidase inhibitor, clade A, member 1C	0.012
Thnsl2	threonine synthase-like 2 (bacterial)	0.012
Slc2a9	solute carrier family 2 (facilitated glucose transporter), member 9	0.011
Slc35b1	solute carrier family 35, member B1	0.011
Creg1	cellular repressor of E1A-stimulated genes 1	0.011
Aldh1b1	aldehyde dehydrogenase 1 family, member B1	0.011
Pepd	peptidase D	0.011
Afm	afamin	0.011
Iah1	isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)	0.011
Ptgr1	prostaglandin reductase 1	0.011
Trub2	TruB pseudouridine (psi) synthase homolog 2 (E. coli)	0.011
Oaz1	ornithine decarboxylase antizyme 1	0.011
Tkt	transketolase	0.011
Slc26a4	solute carrier family 26, member 4	0.011
Angptl3	angiopoietin-like 3	0.011
2310030G06Rik	RIKEN cDNA 2310030G06 gene	0.011
Bhmt	betaine-homocysteine methyltransferase	0.011
Fetub	fetuin beta	0.011
Cst3	cystatin C	0.011
Pgam1	phosphoglycerate mutase 1	0.011
Xylb	xylulokinase homolog (H. influenzae)	0.011
Aadat	aminoadipate aminotransferase	0.011
9030409G11Rik	RIKEN cDNA 9030409G11 gene	0.011
Alas1	aminolevulinic acid synthase 1	0.011
Asl	argininosuccinate lyase	0.011
Mt1	metallothionein 1	0.011
Akr1c19	aldo-keto reductase family 1, member C19	0.011
Plg	plasminogen	0.011
Capns1	calpain, small subunit 1	0.010
Igsf5	immunoglobulin superfamily, member 5	0.010
Mfsd2a	major facilitator superfamily domain containing 2A	0.010
Lect1	leukocyte cell derived chemotaxin 1	0.010
Tmed3	transmembrane emp24 domain containing 3	0.010
Rdh9	retinol dehydrogenase 9	0.010
Rhbg	Rhesus blood group-associated B glycoprotein	0.010
Cyp3a25	cytochrome P450, family 3, subfamily a, polypeptide 25	0.010
Tinag	tubulointerstitial nephritis antigen	0.010
Mpv17l	Mpv17 transgene, kidney disease mutant-like	0.010
Asns	asparagine synthetase	0.010
Pgd	phosphogluconate dehydrogenase	0.010
Folr4	folate receptor 4 (delta)	0.010
Ube2cbp	ubiquitin-conjugating enzyme E2C binding protein	0.010
Ell2	elongation factor RNA polymerase II 2	0.010
Nr1h4	nuclear receptor subfamily 1, group H, member 4	0.010
Arpc1a	actin related protein 2/3 complex, subunit 1A	0.010
2610528J11Rik	RIKEN cDNA 2610528J11 gene	0.010
Gm3150	predicted gene 3150	0.010
Echdc3	enoyl Coenzyme A hydratase domain containing 3	0.010
Naa20	N(alpha)-acetyltransferase 20, NatB catalytic subunit	0.010