IMP: Integrative Multi-species Prediction

Mus musculus

9 genes annotated in mouse

Multi-species View

regulation of cholesterol homeostasis

GO:2000188

Any process that modulates the frequency, rate or extent of cholesterol homeostasis.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of cholesterol homeostasis"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "regulation of cholesterol homeostasis" (in gray)

Name	Description	Probability	Func Analog Organism
Rxra	retinoid X receptor alpha	0.981	Mouse
Rarg	retinoic acid receptor, gamma	0.890	Mouse
Fgfr2	fibroblast growth factor receptor 2	0.854	Mouse
Pax2	paired box gene 2	0.848
Ghr	growth hormone receptor	0.799
Rarb	retinoic acid receptor, beta	0.760	Mouse
Dab1	disabled homolog 1 (Drosophila)	0.675
Thra	thyroid hormone receptor alpha	0.661	Mouse
Pax8	paired box gene 8	0.603
Sox9	SRY-box containing gene 9	0.585
Rara	retinoic acid receptor, alpha	0.583	Mouse
Gli3	GLI-Kruppel family member GLI3	0.449
Pten	phosphatase and tensin homolog	0.448
Fgfr3	fibroblast growth factor receptor 3	0.420	Mouse
Apoe	apolipoprotein E	0.330
Lepr	leptin receptor	0.302
Bmp4	bone morphogenetic protein 4	0.280
Shh	sonic hedgehog	0.255
Fgfr1	fibroblast growth factor receptor 1	0.245	Mouse
Fgfrl1	fibroblast growth factor receptor-like 1	0.204
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.203	Mouse
Dbp	D site albumin promoter binding protein	0.149
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.149	Mouse
Dhcr7	7-dehydrocholesterol reductase	0.145
Prox1	prospero-related homeobox 1	0.142
Vangl2	vang-like 2 (van gogh, Drosophila)	0.137
Foxg1	forkhead box G1	0.133
Nr1h3	nuclear receptor subfamily 1, group H, member 3	0.119
Tef	thyrotroph embryonic factor	0.113
Ece1	endothelin converting enzyme 1	0.113
Esr1	estrogen receptor 1 (alpha)	0.105
Duox2	dual oxidase 2	0.102
Emx2	empty spiracles homolog 2 (Drosophila)	0.099
Pex6	peroxisomal biogenesis factor 6	0.099
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.095
Npc1	Niemann Pick type C1	0.095
Reln	reelin	0.092
Wnt9b	wingless-type MMTV integration site 9B	0.082
Ar	androgen receptor	0.080
Foxc1	forkhead box C1	0.074
Lhx1	LIM homeobox protein 1	0.069
Vldlr	very low density lipoprotein receptor	0.068	Mouse
Pbx1	pre B-cell leukemia transcription factor 1	0.062
Eya1	eyes absent 1 homolog (Drosophila)	0.056
Fgf10	fibroblast growth factor 10	0.055
Dlx5	distal-less homeobox 5	0.055
Prdm16	PR domain containing 16	0.054
Hoxa5	homeobox A5	0.052
Yipf3	Yip1 domain family, member 3	0.051
Notch2	Notch gene homolog 2 (Drosophila)	0.051
Ldlr	low density lipoprotein receptor	0.049
Nr1h2	nuclear receptor subfamily 1, group H, member 2	0.045
Idua	iduronidase, alpha-L-	0.044
Otx2	orthodenticle homolog 2 (Drosophila)	0.043
Vegfa	vascular endothelial growth factor A	0.041
Psen1	presenilin 1	0.041
Fgf9	fibroblast growth factor 9	0.039
Nkx2-1	NK2 homeobox 1	0.039
Rora	RAR-related orphan receptor alpha	0.035
Prlr	prolactin receptor	0.033
Lpin1	lipin 1	0.031
Gna11	guanine nucleotide binding protein, alpha 11	0.030
Pparg	peroxisome proliferator activated receptor gamma	0.029
Ncoa1	nuclear receptor coactivator 1	0.029
Spry2	sprouty homolog 2 (Drosophila)	0.028
Hoxd11	homeobox D11	0.027
Tbx1	T-box 1	0.026
Ptch1	patched homolog 1	0.026
Thrb	thyroid hormone receptor beta	0.025	Mouse
Ppard	peroxisome proliferator activator receptor delta	0.025
Smo	smoothened homolog (Drosophila)	0.025
Smpd3	sphingomyelin phosphodiesterase 3, neutral	0.024
Gli2	GLI-Kruppel family member GLI2	0.024
Sox4	SRY-box containing gene 4	0.024
Bmp5	bone morphogenetic protein 5	0.023
Traf4	TNF receptor associated factor 4	0.022
Scd1	stearoyl-Coenzyme A desaturase 1	0.022
Apoa1	apolipoprotein A-I	0.022
Slc16a2	solute carrier family 16 (monocarboxylic acid transporters), member 2	0.022
Pitx2	paired-like homeodomain transcription factor 2	0.021
Por	P450 (cytochrome) oxidoreductase	0.021
Runx2	runt related transcription factor 2	0.021
Aacs	acetoacetyl-CoA synthetase	0.021
Nr1d1	nuclear receptor subfamily 1, group D, member 1	0.021
Tgfbr2	transforming growth factor, beta receptor II	0.021
Hlf	hepatic leukemia factor	0.021
Mlycd	malonyl-CoA decarboxylase	0.020
Dhcr24	24-dehydrocholesterol reductase	0.020
Srf	serum response factor	0.020
Rbl2	retinoblastoma-like 2	0.019
Lrp6	low density lipoprotein receptor-related protein 6	0.018
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.018
Atxn1	ataxin 1	0.016
Jag1	jagged 1	0.016
Tbx3	T-box 3	0.016
Lrp4	low density lipoprotein receptor-related protein 4	0.016
Npr2	natriuretic peptide receptor 2	0.016
Igf1	insulin-like growth factor 1	0.016
Mmp15	matrix metallopeptidase 15	0.015
Hoxa3	homeobox A3	0.015
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.015
Pcyt2	phosphate cytidylyltransferase 2, ethanolamine	0.015
Nfib	nuclear factor I/B	0.015
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.015
Slc22a1	solute carrier family 22 (organic cation transporter), member 1	0.015
Gata5	GATA binding protein 5	0.014
Cdhr5	cadherin-related family member 5	0.014
Hpn	hepsin	0.014
Foxa2	forkhead box A2	0.014
Irs2	insulin receptor substrate 2	0.014
Klf9	Kruppel-like factor 9	0.013
Ppap2b	phosphatidic acid phosphatase type 2B	0.013
Habp2	hyaluronic acid binding protein 2	0.013
Nfic	nuclear factor I/C	0.013
Vdr	vitamin D receptor	0.013
Sqle	squalene epoxidase	0.013
Tbc1d17	TBC1 domain family, member 17	0.013
Mpv17	MpV17 mitochondrial inner membrane protein	0.013
Crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.013
Dvl3	dishevelled 3, dsh homolog (Drosophila)	0.013
Ptprd	protein tyrosine phosphatase, receptor type, D	0.013
Mib2	mindbomb homolog 2 (Drosophila)	0.013
Stard3	START domain containing 3	0.013
Zfp524	zinc finger protein 524	0.012
Chd7	chromodomain helicase DNA binding protein 7	0.012
Mvd	mevalonate (diphospho) decarboxylase	0.012
Slc25a10	solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10	0.012
Nr1i2	nuclear receptor subfamily 1, group I, member 2	0.012
Gpd1	glycerol-3-phosphate dehydrogenase 1 (soluble)	0.012
Pkdcc	protein kinase domain containing, cytoplasmic	0.012
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.012
Ret	ret proto-oncogene	0.012
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.011
Fasn	fatty acid synthase	0.011
Polrmt	polymerase (RNA) mitochondrial (DNA directed)	0.011
Med25	mediator of RNA polymerase II transcription, subunit 25 homolog (yeast)	0.011
Ednra	endothelin receptor type A	0.011
Adcy9	adenylate cyclase 9	0.011
Cav1	caveolin 1, caveolae protein	0.011
Lss	lanosterol synthase	0.011
Nos3	nitric oxide synthase 3, endothelial cell	0.011
Ndrg2	N-myc downstream regulated gene 2	0.010
ORF61	open reading frame 61	0.010
Acads	acyl-Coenzyme A dehydrogenase, short chain	0.010
Clrn3	clarin 3	0.010
Pklr	pyruvate kinase liver and red blood cell	0.010