IMP: Integrative Multi-species Prediction

Mus musculus

160 genes annotated in mouse

neural tube development

GO:0021915

The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "neural tube development"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "neural tube development" (in gray)

Name	Description	Probability	Func Analog Organism
Gli3	GLI-Kruppel family member GLI3	1.000
Shh	sonic hedgehog	1.000
Vangl2	vang-like 2 (van gogh, Drosophila)	1.000
Otx2	orthodenticle homolog 2 (Drosophila)	1.000	Zebrafish
Pitx2	paired-like homeodomain transcription factor 2	1.000
Foxc1	forkhead box C1	1.000	Mouse
Fgfr2	fibroblast growth factor receptor 2	1.000
Pax6	paired box gene 6	1.000
Rnf2	ring finger protein 2	1.000
Pax2	paired box gene 2	1.000
Pax3	paired box gene 3	1.000
Gli2	GLI-Kruppel family member GLI2	0.999
Bmp4	bone morphogenetic protein 4	0.999
Ctnnb1	catenin (cadherin associated protein), beta 1	0.999
Tcfap2a	transcription factor AP-2, alpha	0.999
Msx2	homeobox, msh-like 2	0.998
Nodal	nodal	0.998
Zic3	zinc finger protein of the cerebellum 3	0.998	Mouse
Psen1	presenilin 1	0.997
Pten	phosphatase and tensin homolog	0.997
Fgf8	fibroblast growth factor 8	0.997
Sox2	SRY-box containing gene 2	0.997	Mouse
Lhx1	LIM homeobox protein 1	0.996	Mouse
Foxg1	forkhead box G1	0.994	Mouse
Foxh1	forkhead box H1	0.994	Zebrafish
Pbx1	pre B-cell leukemia transcription factor 1	0.994
Sall4	sal-like 4 (Drosophila)	0.994
Hand1	heart and neural crest derivatives expressed transcript 1	0.993	Mouse
Alx4	aristaless-like homeobox 4	0.992	Mouse
Fgfr1	fibroblast growth factor receptor 1	0.992
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.990
Mks1	Meckel syndrome, type 1	0.989
Pou5f1	POU domain, class 5, transcription factor 1	0.988
Foxc2	forkhead box C2	0.986	Mouse
Otx1	orthodenticle homolog 1 (Drosophila)	0.985	Zebrafish
Bmp7	bone morphogenetic protein 7	0.984	Mouse
Rarg	retinoic acid receptor, gamma	0.983
Notch1	Notch gene homolog 1 (Drosophila)	0.980
Efnb2	ephrin B2	0.980
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.980	Mouse
Chd7	chromodomain helicase DNA binding protein 7	0.978
Rybp	RING1 and YY1 binding protein	0.977
Lrp6	low density lipoprotein receptor-related protein 6	0.977
Dvl3	dishevelled 3, dsh homolog (Drosophila)	0.976
Fgf10	fibroblast growth factor 10	0.974
Jag1	jagged 1	0.974
Chrd	chordin	0.974
Kif3a	kinesin family member 3A	0.972
Smo	smoothened homolog (Drosophila)	0.969
Notch2	Notch gene homolog 2 (Drosophila)	0.967	Mouse
Arid1a	AT rich interactive domain 1A (SWI-like)	0.966
Smad4	MAD homolog 4 (Drosophila)	0.965
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.964
Megf8	multiple EGF-like-domains 8	0.960
Sox3	SRY-box containing gene 3	0.960	Mouse
Dll1	delta-like 1 (Drosophila)	0.959	Zebrafish
Lmx1b	LIM homeobox transcription factor 1 beta	0.955	Zebrafish Mouse
Lef1	lymphoid enhancer binding factor 1	0.954	Mouse
Sfrp2	secreted frizzled-related protein 2	0.952
Gbx2	gastrulation brain homeobox 2	0.951
Eya1	eyes absent 1 homolog (Drosophila)	0.949
Lmx1a	LIM homeobox transcription factor 1 alpha	0.948	Mouse
Emx2	empty spiracles homolog 2 (Drosophila)	0.944
Ephb2	Eph receptor B2	0.941	Mouse
Sox11	SRY-box containing gene 11	0.941
Apc	adenomatosis polyposis coli	0.939
Wt1	Wilms tumor 1 homolog	0.938
Hoxa11	homeobox A11	0.937
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.934
Hoxa13	homeobox A13	0.934
En1	engrailed 1	0.932
Gdnf	glial cell line derived neurotrophic factor	0.929
Tbx1	T-box 1	0.925	Mouse
Pitx1	paired-like homeodomain transcription factor 1	0.924
Gata4	GATA binding protein 4	0.919
Lhx3	LIM homeobox protein 3	0.917	Mouse
Neurod1	neurogenic differentiation 1	0.916	Mouse
Wnt5a	wingless-related MMTV integration site 5A	0.914
Wnt1	wingless-related MMTV integration site 1	0.912
Hes1	hairy and enhancer of split 1 (Drosophila)	0.912
Ptch1	patched homolog 1	0.907
Tbx15	T-box 15	0.906	Mouse
Nog	noggin	0.902
Smad3	MAD homolog 3 (Drosophila)	0.901
Dlx5	distal-less homeobox 5	0.897
Nanog	Nanog homeobox	0.894
Prrx1	paired related homeobox 1	0.892
Meox2	mesenchyme homeobox 2	0.892
Msx1	homeobox, msh-like 1	0.890
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.876
Insm1	insulinoma-associated 1	0.870
Wnt3a	wingless-related MMTV integration site 3A	0.868
Ptk7	PTK7 protein tyrosine kinase 7	0.866
Hoxd11	homeobox D11	0.861
Pax8	paired box gene 8	0.860	Mouse
Zeb1	zinc finger E-box binding homeobox 1	0.858	Mouse
Col2a1	collagen, type II, alpha 1	0.857
Hoxa1	homeobox A1	0.855
Apaf1	apoptotic peptidase activating factor 1	0.850
Fzd8	frizzled homolog 8 (Drosophila)	0.848	Mouse
Uncx	UNC homeobox	0.838
Ift88	intraflagellar transport 88 homolog (Chlamydomonas)	0.837
Cdx2	caudal type homeobox 2	0.835
Neurog2	neurogenin 2	0.831	Mouse
Smad1	MAD homolog 1 (Drosophila)	0.828
Barx1	BarH-like homeobox 1	0.824
Vegfa	vascular endothelial growth factor A	0.820
Foxd3	forkhead box D3	0.813	Mouse
Shox2	short stature homeobox 2	0.812
Efna2	ephrin A2	0.803
Sall1	sal-like 1 (Drosophila)	0.800
Emx1	empty spiracles homolog 1 (Drosophila)	0.794
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.784
Nkx2-1	NK2 homeobox 1	0.780
Tcfcp2l1	transcription factor CP2-like 1	0.776	Mouse
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.774
Rarb	retinoic acid receptor, beta	0.770	Mouse
Ret	ret proto-oncogene	0.764
Hoxd9	homeobox D9	0.760
Esrrb	estrogen related receptor, beta	0.759
Gdf3	growth differentiation factor 3	0.757	Mouse
Smarcc1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.755
Fgf3	fibroblast growth factor 3	0.750
Dvl2	dishevelled 2, dsh homolog (Drosophila)	0.748
Wnt7b	wingless-related MMTV integration site 7B	0.746	Mouse
Tead2	TEA domain family member 2	0.739
Pkd1	polycystic kidney disease 1 homolog	0.736	Human
Stk3	serine/threonine kinase 3 (Ste20, yeast homolog)	0.733
Zic2	zinc finger protein of the cerebellum 2	0.731
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.719
Fgfr3	fibroblast growth factor receptor 3	0.715
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.711
Pax7	paired box gene 7	0.709
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.709	Zebrafish Mouse
Arhgef11	Rho guanine nucleotide exchange factor (GEF) 11	0.708
Sox9	SRY-box containing gene 9	0.707	Mouse
Hand2	heart and neural crest derivatives expressed transcript 2	0.703	Mouse
Cfc1	cripto, FRL-1, cryptic family 1	0.698	Zebrafish
Hoxa5	homeobox A5	0.697
Gas1	growth arrest specific 1	0.697
Eomes	eomesodermin homolog (Xenopus laevis)	0.689	Mouse
Foxf1a	forkhead box F1a	0.686
Hoxd13	homeobox D13	0.685
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.685
Onecut1	one cut domain, family member 1	0.683
Epha4	Eph receptor A4	0.682	Mouse
Tlx3	T-cell leukemia, homeobox 3	0.678
Lhx6	LIM homeobox protein 6	0.673	Mouse
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.673
Hmx1	H6 homeobox 1	0.663
Efna4	ephrin A4	0.661
Hoxa2	homeobox A2	0.658
T	brachyury	0.657
Ptf1a	pancreas specific transcription factor, 1a	0.652	Mouse
Gpc3	glypican 3	0.646
Hoxb4	homeobox B4	0.643
Lhx9	LIM homeobox protein 9	0.643	Mouse
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.642
Foxa2	forkhead box A2	0.639
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.636
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.631
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.631
Acvr2b	activin receptor IIB	0.628
Tcf15	transcription factor 15	0.617	Mouse
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.616
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.608
Foxd1	forkhead box D1	0.608	Mouse
Tead3	TEA domain family member 3	0.606
Smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.598
Invs	inversin	0.595
Isl1	ISL1 transcription factor, LIM/homeodomain	0.595	Mouse
Pcgf2	polycomb group ring finger 2	0.593	Mouse
Notch3	Notch gene homolog 3 (Drosophila)	0.587	Mouse
Smad6	MAD homolog 6 (Drosophila)	0.586
Fgf15	fibroblast growth factor 15	0.584
Lbx1	ladybird homeobox homolog 1 (Drosophila)	0.584
Hoxa9	homeobox A9	0.582
Dnahc11	dynein, axonemal, heavy chain 11	0.578
Enah	enabled homolog (Drosophila)	0.577
Tal1	T-cell acute lymphocytic leukemia 1	0.575	Mouse
Tcf21	transcription factor 21	0.574
Tgfb2	transforming growth factor, beta 2	0.573
Wls	wntless homolog (Drosophila)	0.573	Zebrafish
Cxadr	coxsackie virus and adenovirus receptor	0.570
Smad5	MAD homolog 5 (Drosophila)	0.557
Fzd2	frizzled homolog 2 (Drosophila)	0.556
Ahi1	Abelson helper integration site 1	0.555
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.552
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.549
Sfrp1	secreted frizzled-related protein 1	0.547
Dll4	delta-like 4 (Drosophila)	0.542
Nf1	neurofibromatosis 1	0.541
Vasp	vasodilator-stimulated phosphoprotein	0.541
Rdh10	retinol dehydrogenase 10 (all-trans)	0.529
Nfia	nuclear factor I/A	0.528
Epha2	Eph receptor A2	0.528
Lhx5	LIM homeobox protein 5	0.527	Mouse
Axin1	axin 1	0.524
Hmx3	H6 homeobox 3	0.523
Cldn6	claudin 6	0.522
Gsc	goosecoid homeobox	0.510
Tcfap2c	transcription factor AP-2, gamma	0.510	Mouse
Arx	aristaless related homeobox	0.509	Mouse
Ldb1	LIM domain binding 1	0.506
Foxa1	forkhead box A1	0.506
Fzd1	frizzled homolog 1 (Drosophila)	0.505
Pax1	paired box gene 1	0.504	Mouse
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.500
Ebf3	early B-cell factor 3	0.500
Gli1	GLI-Kruppel family member GLI1	0.495	Zebrafish Mouse
Vhl	von Hippel-Lindau tumor suppressor	0.494
L3mbtl2	l(3)mbt-like 2 (Drosophila)	0.489
Tbl1xr1	transducin (beta)-like 1X-linked receptor 1	0.488
Neurog1	neurogenin 1	0.486	Mouse
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.485
Pax9	paired box gene 9	0.481	Mouse
Isl2	insulin related protein 2 (islet 2)	0.480	Mouse
Lrp2	low density lipoprotein receptor-related protein 2	0.480	Mouse
Gdf11	growth differentiation factor 11	0.478
Smarcd1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.474
Tbx2	T-box 2	0.467	Mouse
Mta2	metastasis-associated gene family, member 2	0.466
She	src homology 2 domain-containing transforming protein E	0.466
Pou3f3	POU domain, class 3, transcription factor 3	0.464
Gata3	GATA binding protein 3	0.462
Npr3	natriuretic peptide receptor 3	0.462
Hoxa10	homeobox A10	0.461
Cbx2	chromobox homolog 2 (Drosophila Pc class)	0.460
Pou3f1	POU domain, class 3, transcription factor 1	0.457
Vangl1	vang-like 1 (van gogh, Drosophila)	0.457	Mouse
Wnt6	wingless-related MMTV integration site 6	0.457	Mouse
Fgf4	fibroblast growth factor 4	0.449
Yap1	yes-associated protein 1	0.449
Capn6	calpain 6	0.448
Lama5	laminin, alpha 5	0.444
Sin3a	transcriptional regulator, SIN3A (yeast)	0.444
Fat4	FAT tumor suppressor homolog 4 (Drosophila)	0.440
Pou4f2	POU domain, class 4, transcription factor 2	0.439
Pou3f2	POU domain, class 3, transcription factor 2	0.432
Magel2	melanoma antigen, family L, 2	0.429
Mll1	myeloid/lymphoid or mixed-lineage leukemia 1	0.426
Fgf5	fibroblast growth factor 5	0.423
Msi1	Musashi homolog 1(Drosophila)	0.421
St8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.420
Hic1	hypermethylated in cancer 1	0.419
Bcl2	B-cell leukemia/lymphoma 2	0.418
Hes5	hairy and enhancer of split 5 (Drosophila)	0.417
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.415
Cdh13	cadherin 13	0.412
Efs	embryonal Fyn-associated substrate	0.410
Foxj1	forkhead box J1	0.409
Emid2	EMI domain containing 2	0.408
Snai1	snail homolog 1 (Drosophila)	0.404
Trp53	transformation related protein 53	0.402
Mecom	MDS1 and EVI1 complex locus	0.400
Efnb1	ephrin B1	0.400
Amhr2	anti-Mullerian hormone type 2 receptor	0.400
Sall3	sal-like 3 (Drosophila)	0.400	Mouse
Evl	Ena-vasodilator stimulated phosphoprotein	0.399	Mouse
Irx3	Iroquois related homeobox 3 (Drosophila)	0.398
Irx2	Iroquois related homeobox 2 (Drosophila)	0.397
Sox7	SRY-box containing gene 7	0.395	Mouse
Fgf9	fibroblast growth factor 9	0.394
Bnc1	basonuclin 1	0.394
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.391
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.390
Tbx3	T-box 3	0.388	Mouse
Acvr1	activin A receptor, type 1	0.387
Casp1	caspase 1	0.386	Mouse
Htt	huntingtin	0.384	Zebrafish
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.384
Sh3rf1	SH3 domain containing ring finger 1	0.382
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.380
Ncoa3	nuclear receptor coactivator 3	0.379
Celsr1	cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)	0.377
Arhgef12	Rho guanine nucleotide exchange factor (GEF) 12	0.376
Prrx2	paired related homeobox 2	0.374
Itga3	integrin alpha 3	0.373
Irx1	Iroquois related homeobox 1 (Drosophila)	0.373
Grb10	growth factor receptor bound protein 10	0.370
Nacc1	nucleus accumbens associated 1, BEN and BTB (POZ) domain containing	0.369
Gata6	GATA binding protein 6	0.369
Ssbp3	single-stranded DNA binding protein 3	0.368
Rb1	retinoblastoma 1	0.365
Egr1	early growth response 1	0.364
Prox1	prospero-related homeobox 1	0.364
Tsc2	tuberous sclerosis 2	0.362
Rock2	Rho-associated coiled-coil containing protein kinase 2	0.361
Nes	nestin	0.360
Fjx1	four jointed box 1 (Drosophila)	0.360
Setdb1	SET domain, bifurcated 1	0.359
Csnk2a1	casein kinase 2, alpha 1 polypeptide	0.358
Hhex	hematopoietically expressed homeobox	0.357
Hoxb6	homeobox B6	0.356
Neurog3	neurogenin 3	0.356	Mouse
Mmp24	matrix metallopeptidase 24	0.355
Nhlh1	nescient helix loop helix 1	0.355	Mouse
Cachd1	cache domain containing 1	0.351
Myog	myogenin	0.351
Zfp185	zinc finger protein 185	0.349
Fgf18	fibroblast growth factor 18	0.348	Mouse
Rax	retina and anterior neural fold homeobox	0.341
Pofut1	protein O-fucosyltransferase 1	0.340
Axin2	axin2	0.339
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.338
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.336
Cbx8	chromobox homolog 8 (Drosophila Pc class)	0.336
Zfp316	zinc finger protein 316	0.336
Nr0b1	nuclear receptor subfamily 0, group B, member 1	0.331
Irx5	Iroquois related homeobox 5 (Drosophila)	0.330
Hoxa3	homeobox A3	0.330
Ldb2	LIM domain binding 2	0.328
Lhx2	LIM homeobox protein 2	0.328
Lfng	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	0.327
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.325
Wasf1	WASP family 1	0.324
Tgfa	transforming growth factor alpha	0.324
Hoxb7	homeobox B7	0.321
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.318
Arvcf	armadillo repeat gene deleted in velo-cardio-facial syndrome	0.317
Dvl1	dishevelled, dsh homolog 1 (Drosophila)	0.316
Phlda2	pleckstrin homology-like domain, family A, member 2	0.315
Hesx1	homeobox gene expressed in ES cells	0.312
Vax1	ventral anterior homeobox containing gene 1	0.312
Tlx2	T-cell leukemia, homeobox 2	0.308
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.307
Lefty1	left right determination factor 1	0.302
Igf2bp1	insulin-like growth factor 2 mRNA binding protein 1	0.298
Trove2	TROVE domain family, member 2	0.298
Cer1	cerberus 1 homolog (Xenopus laevis)	0.294
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.293
Ssbp2	single-stranded DNA binding protein 2	0.292	Mouse
Igfbpl1	insulin-like growth factor binding protein-like 1	0.291
Foxd2	forkhead box D2	0.289	Mouse
Mrc2	mannose receptor, C type 2	0.288
Mnx1	motor neuron and pancreas homeobox 1	0.285
Pvrl1	poliovirus receptor-related 1	0.285
Sox4	SRY-box containing gene 4	0.284
Zic1	zinc finger protein of the cerebellum 1	0.284	Mouse
Col12a1	collagen, type XII, alpha 1	0.281
Hoxd1	homeobox D1	0.281
Runx2	runt related transcription factor 2	0.281
Hoxc4	homeobox C4	0.279
Fgf17	fibroblast growth factor 17	0.277	Mouse
Emp2	epithelial membrane protein 2	0.277
Pou3f4	POU domain, class 3, transcription factor 4	0.277
Dlg1	discs, large homolog 1 (Drosophila)	0.275
Bmper	BMP-binding endothelial regulator	0.275
Peg10	paternally expressed 10	0.275
Eya4	eyes absent 4 homolog (Drosophila)	0.274
Bcor	BCL6 interacting corepressor	0.273
Fign	fidgetin	0.273
Rspo1	R-spondin homolog (Xenopus laevis)	0.273
Traf6	TNF receptor-associated factor 6	0.272
Zfp358	zinc finger protein 358	0.272
Pbx3	pre B-cell leukemia transcription factor 3	0.272
Usp9x	ubiquitin specific peptidase 9, X chromosome	0.271
Dlx1	distal-less homeobox 1	0.271
Zfp503	zinc finger protein 503	0.268
Fgfr4	fibroblast growth factor receptor 4	0.266
Gdf1	growth differentiation factor 1	0.263	Mouse
Aif1l	allograft inflammatory factor 1-like	0.261
Fam64a	family with sequence similarity 64, member A	0.260
Nynrin	NYN domain and retroviral integrase containing	0.259
Tulp1	tubby like protein 1	0.258	Mouse
Creb1	cAMP responsive element binding protein 1	0.257
Prkar2a	protein kinase, cAMP dependent regulatory, type II alpha	0.255
Adra2b	adrenergic receptor, alpha 2b	0.255
Junb	Jun-B oncogene	0.253
Foxq1	forkhead box Q1	0.253	Mouse
Cldn4	claudin 4	0.253
Wnt2b	wingless related MMTV integration site 2b	0.252	Mouse
Tcfap2b	transcription factor AP-2 beta	0.250	Mouse
Hes3	hairy and enhancer of split 3 (Drosophila)	0.248
Mta1	metastasis associated 1	0.246
Sim2	single-minded homolog 2 (Drosophila)	0.246	Mouse
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.244
Crb2	crumbs homolog 2 (Drosophila)	0.244
Ikbkb	inhibitor of kappaB kinase beta	0.243
Myf5	myogenic factor 5	0.243
Nkx6-1	NK6 homeobox 1	0.243
Cdx1	caudal type homeobox 1	0.240
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.238
Pdgfb	platelet derived growth factor, B polypeptide	0.237
En2	engrailed 2	0.235	Zebrafish Mouse
Cldn3	claudin 3	0.235
Evx1	even skipped homeotic gene 1 homolog	0.235
Eif2c1	eukaryotic translation initiation factor 2C, 1	0.234
Rac3	RAS-related C3 botulinum substrate 3	0.234
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.233
Bbs2	Bardet-Biedl syndrome 2 (human)	0.233
Sema5b	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B	0.233
Mab21l2	mab-21-like 2 (C. elegans)	0.232
Sema5a	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.230
Mycl1	v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)	0.229
Drd2	dopamine receptor D2	0.227
Ntf3	neurotrophin 3	0.226
Myod1	myogenic differentiation 1	0.226
Fev	FEV (ETS oncogene family)	0.225
Nfib	nuclear factor I/B	0.225
Pitx3	paired-like homeodomain transcription factor 3	0.223
Meis2	Meis homeobox 2	0.222	Mouse
Lmo1	LIM domain only 1	0.220	Mouse
Rprm	reprimo, TP53 dependent G2 arrest mediator candidate	0.220
Myf6	myogenic factor 6	0.220
Hoxa7	homeobox A7	0.218
Hoxb1	homeobox B1	0.217	Zebrafish
Hoxb13	homeobox B13	0.217
Hoxb2	homeobox B2	0.215
Hoxc8	homeobox C8	0.214
Tacr2	tachykinin receptor 2	0.214
Alx3	aristaless-like homeobox 3	0.214	Mouse
Rgnef	Rho-guanine nucleotide exchange factor	0.213
Ephb4	Eph receptor B4	0.213	Mouse
Pfn2	profilin 2	0.213	Mouse
Bok	BCL2-related ovarian killer protein	0.212
Wiz	widely-interspaced zinc finger motifs	0.212
Gopc	golgi associated PDZ and coiled-coil motif containing	0.210
Phc1	polyhomeotic-like 1 (Drosophila)	0.210
Nrk	Nik related kinase	0.208
Bmi1	Bmi1 polycomb ring finger oncogene	0.207
Hoxd3	homeobox D3	0.207
Rara	retinoic acid receptor, alpha	0.207
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.207
Bdnf	brain derived neurotrophic factor	0.206
Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.206
Irs1	insulin receptor substrate 1	0.206
Foxf2	forkhead box F2	0.205
Kcne1l	potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene	0.205
Evx2	even skipped homeotic gene 2 homolog	0.204
Pou4f3	POU domain, class 4, transcription factor 3	0.203
Fscn1	fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)	0.203
Barx2	BarH-like homeobox 2	0.203
Sox21	SRY-box containing gene 21	0.202
Epha8	Eph receptor A8	0.202	Mouse
Fos	FBJ osteosarcoma oncogene	0.202
Gzmf	granzyme F	0.201
Myc	myelocytomatosis oncogene	0.200
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.200
Tgfbr3	transforming growth factor, beta receptor III	0.199
Actb	actin, beta	0.198
Prop1	paired like homeodomain factor 1	0.198
Tsc1	tuberous sclerosis 1	0.197
Matn3	matrilin 3	0.194
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.194
Tgif1	TGFB-induced factor homeobox 1	0.194
Hoxc5	homeobox C5	0.194
Phox2b	paired-like homeobox 2b	0.193
Pml	promyelocytic leukemia	0.192
Bcl6b	B-cell CLL/lymphoma 6, member B	0.191
Utf1	undifferentiated embryonic cell transcription factor 1	0.190
Ncoa6	nuclear receptor coactivator 6	0.190
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.190
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.189
Ski	ski sarcoma viral oncogene homolog (avian)	0.189
Hoxa4	homeobox A4	0.189
Tal2	T-cell acute lymphocytic leukemia 2	0.189	Mouse
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.189
Fbn2	fibrillin 2	0.188
Phc2	polyhomeotic-like 2 (Drosophila)	0.187
Tcf4	transcription factor 4	0.185
Ctf1	cardiotrophin 1	0.185
Ephb3	Eph receptor B3	0.183	Mouse
Nck2	non-catalytic region of tyrosine kinase adaptor protein 2	0.183
Pkd2	polycystic kidney disease 2	0.182	Human
Nkd1	naked cuticle 1 homolog (Drosophila)	0.182
Olfr70	olfactory receptor 70	0.181
Cdk1	cyclin-dependent kinase 1	0.181
Ptch2	patched homolog 2	0.180	Mouse
Jun	Jun oncogene	0.180
Mgat3	mannoside acetylglucosaminyltransferase 3	0.180
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.180	Mouse
Meox1	mesenchyme homeobox 1	0.178
Ep300	E1A binding protein p300	0.176
Sim1	single-minded homolog 1 (Drosophila)	0.176	Mouse
Tab2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.176
Tcf3	transcription factor 3	0.175
Epha5	Eph receptor A5	0.174	Mouse
Plxna3	plexin A3	0.174	Mouse
Apba2	amyloid beta (A4) precursor protein-binding, family A, member 2	0.173
Hdac7	histone deacetylase 7	0.173
Ctnnd1	catenin (cadherin associated protein), delta 1	0.172
Arpc4	actin related protein 2/3 complex, subunit 4	0.171
Cdk14	cyclin-dependent kinase 14	0.170
Kiss1	KiSS-1 metastasis-suppressor	0.170
Trim62	tripartite motif-containing 62	0.169
Smpd3	sphingomyelin phosphodiesterase 3, neutral	0.169
Sp1	trans-acting transcription factor 1	0.169
Wdr5	WD repeat domain 5	0.168
Pthlh	parathyroid hormone-like peptide	0.167
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.166
Smad7	MAD homolog 7 (Drosophila)	0.166
Atp7b	ATPase, Cu++ transporting, beta polypeptide	0.166
Pcdh12	protocadherin 12	0.165
Wnt4	wingless-related MMTV integration site 4	0.165	Mouse
Acan	aggrecan	0.164
Prc1	protein regulator of cytokinesis 1	0.164
Tcf7	transcription factor 7, T-cell specific	0.163
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.163	Mouse
Pik3c2a	phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide	0.163
Esx1	extraembryonic, spermatogenesis, homeobox 1	0.162
Jag2	jagged 2	0.161
Spna2	spectrin alpha 2	0.161
Dbx1	developing brain homeobox 1	0.160
Ier2	immediate early response 2	0.160
Gtf2ird1	general transcription factor II I repeat domain-containing 1	0.159
Pkn2	protein kinase N2	0.158
Efna5	ephrin A5	0.158
Gsk3b	glycogen synthase kinase 3 beta	0.157
Twist1	twist homolog 1 (Drosophila)	0.157
Arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.157
Kdm1a	lysine (K)-specific demethylase 1A	0.157
Mpp5	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)	0.157	Zebrafish
Mecp2	methyl CpG binding protein 2	0.155
Ebf2	early B-cell factor 2	0.155
Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	0.155
Birc3	baculoviral IAP repeat-containing 3	0.154
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.153
Rnf44	ring finger protein 44	0.153
Cilp2	cartilage intermediate layer protein 2	0.153
Nkx3-1	NK-3 transcription factor, locus 1 (Drosophila)	0.152
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.152
E2f1	E2F transcription factor 1	0.152
Zic4	zinc finger protein of the cerebellum 4	0.152	Mouse
Atoh1	atonal homolog 1 (Drosophila)	0.152	Mouse
App	amyloid beta (A4) precursor protein	0.152
Crebbp	CREB binding protein	0.151
Prdm16	PR domain containing 16	0.151
Dmbx1	diencephalon/mesencephalon homeobox 1	0.150
Arsi	arylsulfatase i	0.149
Shroom3	shroom family member 3	0.149
Ccnd1	cyclin D1	0.149
Scrt2	scratch homolog 2, zinc finger protein (Drosophila)	0.149
Hnf1a	HNF1 homeobox A	0.148
Fgf6	fibroblast growth factor 6	0.148
Smad2	MAD homolog 2 (Drosophila)	0.148
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.147
Hoxd8	homeobox D8	0.147
Tgif2	TGFB-induced factor homeobox 2	0.147	Mouse
Nfya	nuclear transcription factor-Y alpha	0.147
Tpbg	trophoblast glycoprotein	0.146
Tbx4	T-box 4	0.146	Mouse
Gja5	gap junction protein, alpha 5	0.146
2700081O15Rik	RIKEN cDNA 2700081O15 gene	0.146
Foxe3	forkhead box E3	0.145	Mouse
Arid3a	AT rich interactive domain 3A (BRIGHT-like)	0.145	Mouse
Tead4	TEA domain family member 4	0.144	Mouse
Gja1	gap junction protein, alpha 1	0.144
Lhx4	LIM homeobox protein 4	0.144	Mouse
Kifap3	kinesin-associated protein 3	0.144
Trip12	thyroid hormone receptor interactor 12	0.143
Msx3	homeobox, msh-like 3	0.143
Zfhx4	zinc finger homeodomain 4	0.143
Hoxb9	homeobox B9	0.143
Sox1	SRY-box containing gene 1	0.143
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.142
Ncor2	nuclear receptor co-repressor 2	0.142
Zcchc14	zinc finger, CCHC domain containing 14	0.141
Adrb1	adrenergic receptor, beta 1	0.141
Iqcb1	IQ calmodulin-binding motif containing 1	0.141
Ednra	endothelin receptor type A	0.141
Wrn	Werner syndrome homolog (human)	0.140
Nr2e1	nuclear receptor subfamily 2, group E, member 1	0.140
Sox14	SRY-box containing gene 14	0.139
Ybx2	Y box protein 2	0.139
Zfpm2	zinc finger protein, multitype 2	0.139
Pcdh18	protocadherin 18	0.139
Plekha7	pleckstrin homology domain containing, family A member 7	0.139
Atp6v1a	ATPase, H+ transporting, lysosomal V1 subunit A	0.138
Madcam1	mucosal vascular addressin cell adhesion molecule 1	0.138
Btbd3	BTB (POZ) domain containing 3	0.138
Dlx4	distal-less homeobox 4	0.138
Aff1	AF4/FMR2 family, member 1	0.138
Fhl3	four and a half LIM domains 3	0.138
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.137
Sfn	stratifin	0.137
Inhbb	inhibin beta-B	0.137
Hoxd4	homeobox D4	0.137
Myh10	myosin, heavy polypeptide 10, non-muscle	0.137
Nf2	neurofibromatosis 2	0.136
Galr1	galanin receptor 1	0.136
Hoxd12	homeobox D12	0.135
Trip6	thyroid hormone receptor interactor 6	0.134
Ar	androgen receptor	0.134
Fzd3	frizzled homolog 3 (Drosophila)	0.134
Cacng7	calcium channel, voltage-dependent, gamma subunit 7	0.134
Spry2	sprouty homolog 2 (Drosophila)	0.134
Tcfap2d	transcription factor AP-2, delta	0.134
Zfp36l1	zinc finger protein 36, C3H type-like 1	0.133
Twsg1	twisted gastrulation homolog 1 (Drosophila)	0.133
Rhbdl3	rhomboid, veinlet-like 3 (Drosophila)	0.133
Tcof1	Treacher Collins Franceschetti syndrome 1, homolog	0.133
Ntn1	netrin 1	0.132
Sirpa	signal-regulatory protein alpha	0.132
Ift140	intraflagellar transport 140 homolog (Chlamydomonas)	0.132
Fzd6	frizzled homolog 6 (Drosophila)	0.132
Nfe2l3	nuclear factor, erythroid derived 2, like 3	0.131
Btg1	B-cell translocation gene 1, anti-proliferative	0.131
Insm2	insulinoma-associated 2	0.131
Per3	period homolog 3 (Drosophila)	0.131
Fgf2	fibroblast growth factor 2	0.130
Osr1	odd-skipped related 1 (Drosophila)	0.130
Plxna2	plexin A2	0.130
Pcdh10	protocadherin 10	0.130
Mdfi	MyoD family inhibitor	0.130
Gpr124	G protein-coupled receptor 124	0.129
Runx1t1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.129
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.129
Epha3	Eph receptor A3	0.129	Mouse
Boc	biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein	0.129
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.129
Otog	otogelin	0.128
Gpr50	G-protein-coupled receptor 50	0.127
Tmprss6	transmembrane serine protease 6	0.127
Krt27	keratin 27	0.127
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.127
Arhgdia	Rho GDP dissociation inhibitor (GDI) alpha	0.127
Fam171a1	family with sequence similarity 171, member A1	0.127
Rab25	RAB25, member RAS oncogene family	0.126
Klf6	Kruppel-like factor 6	0.126
Tecta	tectorin alpha	0.126
Ccnb2	cyclin B2	0.126
Racgap1	Rac GTPase-activating protein 1	0.126
Dhh	desert hedgehog	0.126	Mouse
Spin1	spindlin 1	0.125
Angpt1	angiopoietin 1	0.125
Cldn7	claudin 7	0.125
Chrna3	cholinergic receptor, nicotinic, alpha polypeptide 3	0.125
Hoxb5	homeobox B5	0.125
Mab21l1	mab-21-like 1 (C. elegans)	0.124
Zbtb46	zinc finger and BTB domain containing 46	0.124
Robo1	roundabout homolog 1 (Drosophila)	0.124
Zfhx3	zinc finger homeobox 3	0.124
Edar	ectodysplasin-A receptor	0.123
Dmrt3	doublesex and mab-3 related transcription factor 3	0.123
Nrp1	neuropilin 1	0.123
Sox10	SRY-box containing gene 10	0.123	Mouse
Prph2	peripherin 2	0.122
Myo6	myosin VI	0.122
Ier5l	immediate early response 5-like	0.122
Kdm6a	4lysine (K)-specific demethylase 6A	0.121
Rbl1	retinoblastoma-like 1 (p107)	0.121
Tmeff2	transmembrane protein with EGF-like and two follistatin-like domains 2	0.121
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.121
Unc5c	unc-5 homolog C (C. elegans)	0.121
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.120
Cxcr4	chemokine (C-X-C motif) receptor 4	0.120
Miox	myo-inositol oxygenase	0.120
Mfap2	microfibrillar-associated protein 2	0.120
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.120
Mapk7	mitogen-activated protein kinase 7	0.119
Nfatc4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	0.119
Fosl2	fos-like antigen 2	0.119
Csk	c-src tyrosine kinase	0.118
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.118
Mid2	midline 2	0.118
Foxp2	forkhead box P2	0.118
Sox17	SRY-box containing gene 17	0.118
Il18	interleukin 18	0.117
Tdgf1	teratocarcinoma-derived growth factor 1	0.117	Zebrafish
Duoxa1	dual oxidase maturation factor 1	0.117
Tacr1	tachykinin receptor 1	0.117
Ccnb1	cyclin B1	0.117
Mmp15	matrix metallopeptidase 15	0.117
Pbx2	pre B-cell leukemia transcription factor 2	0.116
Calcr	calcitonin receptor	0.116
Polr2a	polymerase (RNA) II (DNA directed) polypeptide A	0.116
Etv2	ets variant gene 2	0.116
Hif1a	hypoxia inducible factor 1, alpha subunit	0.115
Pygo1	pygopus 1	0.115
Cdk5r2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.115
Hif3a	hypoxia inducible factor 3, alpha subunit	0.115	Mouse
Rem1	rad and gem related GTP binding protein 1	0.115
Plxnb1	plexin B1	0.115	Mouse
Hoxb3	homeobox B3	0.115
Amh	anti-Mullerian hormone	0.114
Fam83h	family with sequence similarity 83, member H	0.114
Onecut2	one cut domain, family member 2	0.113
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.113
Calca	calcitonin/calcitonin-related polypeptide, alpha	0.113
Gna13	guanine nucleotide binding protein, alpha 13	0.113
Nkain1	Na+/K+ transporting ATPase interacting 1	0.113
Dync1h1	dynein cytoplasmic 1 heavy chain 1	0.113
Igfbp2	insulin-like growth factor binding protein 2	0.113
Twist2	twist homolog 2 (Drosophila)	0.113	Mouse
Elavl3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	0.113
Cask	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	0.113
Men1	multiple endocrine neoplasia 1	0.113
Cdc42ep1	CDC42 effector protein (Rho GTPase binding) 1	0.112
Efnb3	ephrin B3	0.111
Lrp4	low density lipoprotein receptor-related protein 4	0.111	Mouse
Dll3	delta-like 3 (Drosophila)	0.110
Cotl1	coactosin-like 1 (Dictyostelium)	0.110
Irx4	Iroquois related homeobox 4 (Drosophila)	0.110
Cdkn1c	cyclin-dependent kinase inhibitor 1C (P57)	0.109
Whrn	whirlin	0.109
Myo10	myosin X	0.109
Rbl2	retinoblastoma-like 2	0.109
Ctbp2	C-terminal binding protein 2	0.109
Dusp1	dual specificity phosphatase 1	0.108
Cd2ap	CD2-associated protein	0.108
Gm98	predicted gene 98	0.108
Fbxw7	F-box and WD-40 domain protein 7	0.108
Stra6	stimulated by retinoic acid gene 6	0.107
Nrp2	neuropilin 2	0.107
Sox5	SRY-box containing gene 5	0.107
Foxb2	forkhead box B2	0.107	Mouse
Amotl2	angiomotin-like 2	0.106
Crabp2	cellular retinoic acid binding protein II	0.106
B9d1	B9 protein domain 1	0.105
Fzd7	frizzled homolog 7 (Drosophila)	0.105	Mouse
Sema3e	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E	0.105	Mouse
Arf5	ADP-ribosylation factor 5	0.105
Cep55	centrosomal protein 55	0.105
Trp53bp2	transformation related protein 53 binding protein 2	0.105
Hoxc9	homeobox C9	0.105
Pvrl2	poliovirus receptor-related 2	0.105
Col11a1	collagen, type XI, alpha 1	0.104
Pcgf6	polycomb group ring finger 6	0.104	Mouse
Bmp5	bone morphogenetic protein 5	0.104	Mouse
Cd40	CD40 antigen	0.104
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.104
Klf3	Kruppel-like factor 3 (basic)	0.104
Hnf4a	hepatic nuclear factor 4, alpha	0.103
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.103
Epor	erythropoietin receptor	0.103
Cltc	clathrin, heavy polypeptide (Hc)	0.103
Plac1	placental specific protein 1	0.103
Tbk1	TANK-binding kinase 1	0.103
Dcaf7	DDB1 and CUL4 associated factor 7	0.103
Gpr27	G protein-coupled receptor 27	0.102
Elavl2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)	0.102
Ltbr	lymphotoxin B receptor	0.102
Ccdc88a	coiled coil domain containing 88A	0.102
Wnt9a	wingless-type MMTV integration site 9A	0.102	Mouse
Acvr2a	activin receptor IIA	0.102
H1fx	H1 histone family, member X	0.101
Sox13	SRY-box containing gene 13	0.101
Aldh1a3	aldehyde dehydrogenase family 1, subfamily A3	0.101
Wwc1	WW, C2 and coiled-coil domain containing 1	0.101
Cc2d2a	coiled-coil and C2 domain containing 2A	0.101
Olfr155	olfactory receptor 155	0.101
Numb	numb gene homolog (Drosophila)	0.100
Map3k11	mitogen-activated protein kinase kinase kinase 11	0.100
Mafb	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.100
Ncs1	neuronal calcium sensor 1	0.100
Fzd5	frizzled homolog 5 (Drosophila)	0.100	Mouse
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.100	Zebrafish
Fst	follistatin	0.099
Nkx2-4	NK2 transcription factor related, locus 4 (Drosophila)	0.099