IMP: Integrative Multi-species Prediction

Mus musculus

67 genes annotated in mouse

hepaticobiliary system development

The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "hepaticobiliary system development"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "hepaticobiliary system development" (in gray)

Name	Description	Probability	Func Analog Organism
Fgfr2	fibroblast growth factor receptor 2	0.997	Zebrafish
Pten	phosphatase and tensin homolog	0.994
Gata4	GATA binding protein 4	0.989	Zebrafish Mouse
Bmp4	bone morphogenetic protein 4	0.986	Zebrafish Rat
Stat3	signal transducer and activator of transcription 3	0.946
Pitx2	paired-like homeodomain transcription factor 2	0.941
Hes1	hairy and enhancer of split 1 (Drosophila)	0.934
Shh	sonic hedgehog	0.922
Fgf8	fibroblast growth factor 8	0.901
Notch1	Notch gene homolog 1 (Drosophila)	0.870
Gli3	GLI-Kruppel family member GLI3	0.867
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.861
Onecut1	one cut domain, family member 1	0.839
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.824
Pkd1	polycystic kidney disease 1 homolog	0.813
Chd7	chromodomain helicase DNA binding protein 7	0.809
Tgfbr2	transforming growth factor, beta receptor II	0.792
Meox2	mesenchyme homeobox 2	0.780
Isl1	ISL1 transcription factor, LIM/homeodomain	0.760
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.742
Hand2	heart and neural crest derivatives expressed transcript 2	0.742
Vegfa	vascular endothelial growth factor A	0.740
Hhex	hematopoietically expressed homeobox	0.709
Axl	AXL receptor tyrosine kinase	0.654	Mouse
Rxra	retinoid X receptor alpha	0.623	Rat
Acvr1	activin A receptor, type 1	0.621
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.619
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.618
Pax3	paired box gene 3	0.604
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.599
Smad4	MAD homolog 4 (Drosophila)	0.589	Mouse
Trp53	transformation related protein 53	0.580
Smad3	MAD homolog 3 (Drosophila)	0.549
Nos3	nitric oxide synthase 3, endothelial cell	0.535
Pbx1	pre B-cell leukemia transcription factor 1	0.535
Ptgs2	prostaglandin-endoperoxide synthase 2	0.526
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.513
Ret	ret proto-oncogene	0.511
Apoe	apolipoprotein E	0.499
Chrd	chordin	0.478
Foxa2	forkhead box A2	0.474
Gopc	golgi associated PDZ and coiled-coil motif containing	0.468
Rb1	retinoblastoma 1	0.465
Hnf4a	hepatic nuclear factor 4, alpha	0.459
Alx4	aristaless-like homeobox 4	0.452
Nodal	nodal	0.451
Tbx1	T-box 1	0.449
Gata6	GATA binding protein 6	0.436
Apc	adenomatosis polyposis coli	0.403
Nos1	nitric oxide synthase 1, neuronal	0.390	Zebrafish
Fos	FBJ osteosarcoma oncogene	0.389
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.388
Fgfr1	fibroblast growth factor receptor 1	0.376	Zebrafish
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.374
Cdk6	cyclin-dependent kinase 6	0.373
Smad6	MAD homolog 6 (Drosophila)	0.367	Mouse
Jag1	jagged 1	0.366	Zebrafish
Gdnf	glial cell line derived neurotrophic factor	0.355
Rarg	retinoic acid receptor, gamma	0.346	Zebrafish
Nf1	neurofibromatosis 1	0.341
Sox17	SRY-box containing gene 17	0.337
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.329
Pax2	paired box gene 2	0.322
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.317
Notch2	Notch gene homolog 2 (Drosophila)	0.297	Zebrafish Mouse
Ece1	endothelin converting enzyme 1	0.296
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.292
Dll1	delta-like 1 (Drosophila)	0.289	Zebrafish
Tcfap2a	transcription factor AP-2, alpha	0.273
Gli2	GLI-Kruppel family member GLI2	0.271
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.262
Ezh2	enhancer of zeste homolog 2 (Drosophila)	0.261
Erbb2ip	Erbb2 interacting protein	0.259
Hand1	heart and neural crest derivatives expressed transcript 1	0.251
Fzd1	frizzled homolog 1 (Drosophila)	0.250	Mouse
Gli1	GLI-Kruppel family member GLI1	0.250
Alx3	aristaless-like homeobox 3	0.249
Tef	thyrotroph embryonic factor	0.248
Wnt6	wingless-related MMTV integration site 6	0.244
Wnt5a	wingless-related MMTV integration site 5A	0.243
She	src homology 2 domain-containing transforming protein E	0.241
Mks1	Meckel syndrome, type 1	0.240
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.236
Traf6	TNF receptor-associated factor 6	0.234
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.233
Igh	immunoglobulin heavy chain complex	0.232
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.232	Mouse
Crebbp	CREB binding protein	0.229
Tgfb2	transforming growth factor, beta 2	0.229
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.226	Mouse
Tbx2	T-box 2	0.220
Rarb	retinoic acid receptor, beta	0.218
Cdk4	cyclin-dependent kinase 4	0.215
Tyro3	TYRO3 protein tyrosine kinase 3	0.211	Mouse
Foxc1	forkhead box C1	0.210
Arid1a	AT rich interactive domain 1A (SWI-like)	0.210
Bcl2	B-cell leukemia/lymphoma 2	0.208
Kif3a	kinesin family member 3A	0.206
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.204
Foxp3	forkhead box P3	0.201
Gdf5	growth differentiation factor 5	0.200	Mouse
Creb1	cAMP responsive element binding protein 1	0.197
Bmp2	bone morphogenetic protein 2	0.196	Zebrafish
Tbx3	T-box 3	0.194
Fgf10	fibroblast growth factor 10	0.192	Zebrafish
Mll5	myeloid/lymphoid or mixed-lineage leukemia 5	0.192
Foxo1	forkhead box O1	0.191
Cdk2	cyclin-dependent kinase 2	0.191
Tgfb1	transforming growth factor, beta 1	0.188
Nog	noggin	0.188
Hoxd13	homeobox D13	0.187
Bmp7	bone morphogenetic protein 7	0.185	Mouse
Klf4	Kruppel-like factor 4 (gut)	0.184	Mouse
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.183
Csf1	colony stimulating factor 1 (macrophage)	0.181
Acvrl1	activin A receptor, type II-like 1	0.179
Sfrp2	secreted frizzled-related protein 2	0.179
Smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.179
Ntf3	neurotrophin 3	0.178
Tal1	T-cell acute lymphocytic leukemia 1	0.175
Klf2	Kruppel-like factor 2 (lung)	0.174	Mouse
Sox4	SRY-box containing gene 4	0.172	Mouse
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.172
Wnt3a	wingless-related MMTV integration site 3A	0.169
Gdf1	growth differentiation factor 1	0.168
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.163
Zfpm2	zinc finger protein, multitype 2	0.158
Arid1b	AT rich interactive domain 1B (SWI-like)	0.156
Mapk8	mitogen-activated protein kinase 8	0.155
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.146	Rat
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.144
Foxf1a	forkhead box F1a	0.140
Cldn3	claudin 3	0.138
Axin2	axin2	0.138
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.136	Mouse
Mertk	c-mer proto-oncogene tyrosine kinase	0.136	Mouse
Vdr	vitamin D receptor	0.135
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.135
Zfpm1	zinc finger protein, multitype 1	0.134
Nkx3-1	NK-3 transcription factor, locus 1 (Drosophila)	0.133
Lrp5	low density lipoprotein receptor-related protein 5	0.132
Ptk2	PTK2 protein tyrosine kinase 2	0.131
Dsg4	desmoglein 4	0.131
Apoa1	apolipoprotein A-I	0.131
Phox2a	paired-like homeobox 2a	0.131
Sox3	SRY-box containing gene 3	0.128	Mouse
3110079O15Rik	RIKEN cDNA 3110079O15 gene	0.127
Barx2	BarH-like homeobox 2	0.127	Mouse
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.125
Smad7	MAD homolog 7 (Drosophila)	0.125	Mouse
Yap1	yes-associated protein 1	0.125
Sox7	SRY-box containing gene 7	0.124	Mouse
Fgfr3	fibroblast growth factor receptor 3	0.124
Lrp1	low density lipoprotein receptor-related protein 1	0.123
Ptch2	patched homolog 2	0.121
Fgf15	fibroblast growth factor 15	0.119
Gata3	GATA binding protein 3	0.119	Mouse
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.118
Kdm6a	4lysine (K)-specific demethylase 6A	0.116
Prrx2	paired related homeobox 2	0.116
Hoxb4	homeobox B4	0.115
Serpina10	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.114
Rnf111	ring finger 111	0.114
Tcf21	transcription factor 21	0.113
Wnt3	wingless-related MMTV integration site 3	0.110
Foxa1	forkhead box A1	0.110
F2	coagulation factor II	0.109
Sox9	SRY-box containing gene 9	0.108
Zic3	zinc finger protein of the cerebellum 3	0.108	Human
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.107
Etfa	electron transferring flavoprotein, alpha polypeptide	0.106
Wnt1	wingless-related MMTV integration site 1	0.106
Wnt4	wingless-related MMTV integration site 4	0.106
Invs	inversin	0.105
Gna13	guanine nucleotide binding protein, alpha 13	0.105
Vhl	von Hippel-Lindau tumor suppressor	0.105
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.104
Twist2	twist homolog 2 (Drosophila)	0.101
Gbx2	gastrulation brain homeobox 2	0.100
Col1a1	collagen, type I, alpha 1	0.099
Rhob	ras homolog gene family, member B	0.098
Spag9	sperm associated antigen 9	0.097
Clec4f	C-type lectin domain family 4, member f	0.097
Gpc3	glypican 3	0.096
Epas1	endothelial PAS domain protein 1	0.096
Smo	smoothened homolog (Drosophila)	0.096
Hoxd11	homeobox D11	0.095
Gdf6	growth differentiation factor 6	0.094	Mouse
Pparg	peroxisome proliferator activated receptor gamma	0.094
Evx1	even skipped homeotic gene 1 homolog	0.093
Gab1	growth factor receptor bound protein 2-associated protein 1	0.091
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.091
Cdt1	chromatin licensing and DNA replication factor 1	0.090
Hoxb6	homeobox B6	0.090
En1	engrailed 1	0.089
Sin3a	transcriptional regulator, SIN3A (yeast)	0.089
Icam1	intercellular adhesion molecule 1	0.088
Nkx6-1	NK6 homeobox 1	0.087
Arhgef7	Rho guanine nucleotide exchange factor (GEF7)	0.087
Ncoa6	nuclear receptor coactivator 6	0.087
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.087
Sharpin	SHANK-associated RH domain interacting protein	0.087
Sox18	SRY-box containing gene 18	0.086	Mouse
Jun	Jun oncogene	0.086
Pdgfb	platelet derived growth factor, B polypeptide	0.086
Arid2	AT rich interactive domain 2 (ARID, RFX-like)	0.085
1300017J02Rik	RIKEN cDNA 1300017J02 gene	0.085
Skor1	SKI family transcriptional corepressor 1	0.085
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.084
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.084
Foxd3	forkhead box D3	0.084
Fgf3	fibroblast growth factor 3	0.084
Il10	interleukin 10	0.082
Dlx5	distal-less homeobox 5	0.081
Wnt7b	wingless-related MMTV integration site 7B	0.080
Fgfr4	fibroblast growth factor receptor 4	0.080
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.080
Ccnd2	cyclin D2	0.080	Rat
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.079
Smarcc1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.079
Msx2	homeobox, msh-like 2	0.079
Hoxa9	homeobox A9	0.078
Nos2	nitric oxide synthase 2, inducible	0.077
Mobkl1b	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.077
Phox2b	paired-like homeobox 2b	0.076
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.076	Mouse
Zfp36l2	zinc finger protein 36, C3H type-like 2	0.075
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.075
Ihh	Indian hedgehog	0.074
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.074
Fli1	Friend leukemia integration 1	0.074
Foxd2	forkhead box D2	0.073
Marveld1	MARVEL (membrane-associating) domain containing 1	0.073
Hoxd3	homeobox D3	0.073
Bicc1	bicaudal C homolog 1 (Drosophila)	0.072
Sema5b	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B	0.071
Foxn1	forkhead box N1	0.071
Dll4	delta-like 4 (Drosophila)	0.071
Hoxb3	homeobox B3	0.071
Ednra	endothelin receptor type A	0.071
Kit	kit oncogene	0.071
Npr3	natriuretic peptide receptor 3	0.070
Abca3	ATP-binding cassette, sub-family A (ABC1), member 3	0.070
Ahr	aryl-hydrocarbon receptor	0.070
Smad1	MAD homolog 1 (Drosophila)	0.069	Mouse
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.069
Matn4	matrilin 4	0.069
Parva	parvin, alpha	0.068
C3	complement component 3	0.068
Cxcl12	chemokine (C-X-C motif) ligand 12	0.068
Ski	ski sarcoma viral oncogene homolog (avian)	0.068
Zfhx3	zinc finger homeobox 3	0.068
Pofut1	protein O-fucosyltransferase 1	0.068
Nrg1	neuregulin 1	0.068
Wnt11	wingless-related MMTV integration site 11	0.066
Pthlh	parathyroid hormone-like peptide	0.066
Kcnk2	potassium channel, subfamily K, member 2	0.066
Wdr19	WD repeat domain 19	0.066
Otx2	orthodenticle homolog 2 (Drosophila)	0.066
Onecut2	one cut domain, family member 2	0.066
Pou3f1	POU domain, class 3, transcription factor 1	0.065
Irf6	interferon regulatory factor 6	0.065
Gfi1b	growth factor independent 1B	0.065
Sfrp1	secreted frizzled-related protein 1	0.065
Mesp1	mesoderm posterior 1	0.064
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.064
Bach1	BTB and CNC homology 1	0.064
Hoxa4	homeobox A4	0.063
Tnfrsf19	tumor necrosis factor receptor superfamily, member 19	0.063
E2f1	E2F transcription factor 1	0.063
Hoxa1	homeobox A1	0.063
Rictor	RPTOR independent companion of MTOR, complex 2	0.062
Hoxa3	homeobox A3	0.062
Htr1b	5-hydroxytryptamine (serotonin) receptor 1B	0.062
Sec61a1	Sec61 alpha 1 subunit (S. cerevisiae)	0.062
Myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.062
Kdm5a	lysine (K)-specific demethylase 5A	0.062
Wnt5b	wingless-related MMTV integration site 5B	0.061
Ephb2	Eph receptor B2	0.061
Hlx	H2.0-like homeobox	0.061
Galr3	galanin receptor 3	0.061
Rbl2	retinoblastoma-like 2	0.061
Sp1	trans-acting transcription factor 1	0.060
Plg	plasminogen	0.060	Mouse
Mapk14	mitogen-activated protein kinase 14	0.060
Pgf	placental growth factor	0.058
Cdx1	caudal type homeobox 1	0.058	Zebrafish
Cldn5	claudin 5	0.058
Ctsl	cathepsin L	0.058
Smurf1	SMAD specific E3 ubiquitin protein ligase 1	0.057
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.057
Ilk	integrin linked kinase	0.057
Eya1	eyes absent 1 homolog (Drosophila)	0.057
Hr	hairless	0.057
Arid4a	AT rich interactive domain 4A (RBP1-like)	0.057
Vav2	vav 2 oncogene	0.057
Mafb	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.057
Egr2	early growth response 2	0.056
Slc27a5	solute carrier family 27 (fatty acid transporter), member 5	0.056
Hif1a	hypoxia inducible factor 1, alpha subunit	0.056
Nr2c2	nuclear receptor subfamily 2, group C, member 2	0.055
Bmp6	bone morphogenetic protein 6	0.055	Mouse
Mapk9	mitogen-activated protein kinase 9	0.055
Bmp5	bone morphogenetic protein 5	0.055	Mouse
Ikzf1	IKAROS family zinc finger 1	0.055
Il3	interleukin 3	0.055
Lhx1	LIM homeobox protein 1	0.055
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.055
Rod1	ROD1 regulator of differentiation 1 (S. pombe)	0.054
Ahsg	alpha-2-HS-glycoprotein	0.054
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.054
Runx1	runt related transcription factor 1	0.054
Prkcd	protein kinase C, delta	0.054
Ar	androgen receptor	0.054
Epor	erythropoietin receptor	0.054
Slc16a2	solute carrier family 16 (monocarboxylic acid transporters), member 2	0.053
Scn9a	sodium channel, voltage-gated, type IX, alpha	0.053
Aqp1	aquaporin 1	0.053
Ptf1a	pancreas specific transcription factor, 1a	0.053
Siglec5	sialic acid binding Ig-like lectin 5	0.053
Tbx6	T-box 6	0.053
Hdac1	histone deacetylase 1	0.052	Zebrafish
Hoxa13	homeobox A13	0.052
Igfbp4	insulin-like growth factor binding protein 4	0.052
Gas1	growth arrest specific 1	0.051
Mll1	myeloid/lymphoid or mixed-lineage leukemia 1	0.051
Smad5	MAD homolog 5 (Drosophila)	0.051	Mouse
Spnb2	spectrin beta 2	0.051
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.051
Sox11	SRY-box containing gene 11	0.051	Mouse
Itgb3	integrin beta 3	0.051
Hic1	hypermethylated in cancer 1	0.051
Axin1	axin 1	0.051
Zfp36l1	zinc finger protein 36, C3H type-like 1	0.051
Ncoa3	nuclear receptor coactivator 3	0.050
Ambp	alpha 1 microglobulin/bikunin	0.050
Ncor1	nuclear receptor co-repressor 1	0.050
Ddx6	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6	0.050
Apob	apolipoprotein B	0.050
Btbd17	BTB (POZ) domain containing 17	0.050
Edn3	endothelin 3	0.050
Tcl1	T-cell lymphoma breakpoint 1	0.050
Ift57	intraflagellar transport 57 homolog (Chlamydomonas)	0.049
Igf1	insulin-like growth factor 1	0.049
Try10	trypsin 10	0.049
Pax9	paired box gene 9	0.049
Emx2	empty spiracles homolog 2 (Drosophila)	0.049
Cebpd	CCAAT/enhancer binding protein (C/EBP), delta	0.048
Bmp1	bone morphogenetic protein 1	0.048
Wt1	Wilms tumor 1 homolog	0.048
Hoxd10	homeobox D10	0.048
Serpinf2	serine (or cysteine) peptidase inhibitor, clade F, member 2	0.048
Hlf	hepatic leukemia factor	0.048
Mvd	mevalonate (diphospho) decarboxylase	0.048
ND6	NADH dehydrogenase subunit 6	0.048
Btg2	B-cell translocation gene 2, anti-proliferative	0.047
Eng	endoglin	0.047	Mouse
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.047
Itih1	inter-alpha trypsin inhibitor, heavy chain 1	0.047
Irs1	insulin receptor substrate 1	0.047
Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	0.047
Adrb1	adrenergic receptor, beta 1	0.047
Hoxa11	homeobox A11	0.047
Srcin1	SRC kinase signaling inhibitor 1	0.047
Foxg1	forkhead box G1	0.047
Etfdh	electron transferring flavoprotein, dehydrogenase	0.046
Zfp703	zinc finger protein 703	0.046
Upk2	uroplakin 2	0.046
Bcl3	B-cell leukemia/lymphoma 3	0.046
Cbs	cystathionine beta-synthase	0.046
Vangl2	vang-like 2 (van gogh, Drosophila)	0.046
Fzd8	frizzled homolog 8 (Drosophila)	0.046	Mouse
Hoxc9	homeobox C9	0.045
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.045
Mef2a	myocyte enhancer factor 2A	0.045
Apoh	apolipoprotein H	0.045
Chrna7	cholinergic receptor, nicotinic, alpha polypeptide 7	0.045
Tcf15	transcription factor 15	0.045
Dnahc11	dynein, axonemal, heavy chain 11	0.045
Zfp292	zinc finger protein 292	0.045
Pou3f3	POU domain, class 3, transcription factor 3	0.045
Nfib	nuclear factor I/B	0.044
Klf6	Kruppel-like factor 6	0.044	Zebrafish Mouse
Prrx1	paired related homeobox 1	0.044
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.044	Zebrafish Rat
Fgf4	fibroblast growth factor 4	0.044
Asgr2	asialoglycoprotein receptor 2	0.044
Cyp2d26	cytochrome P450, family 2, subfamily d, polypeptide 26	0.044
Klf10	Kruppel-like factor 10	0.044
Kif19a	kinesin family member 19A	0.044
Snai1	snail homolog 1 (Drosophila)	0.044
Abcc2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.044
Gc	group specific component	0.043
Pex7	peroxisomal biogenesis factor 7	0.043
Pitx3	paired-like homeodomain transcription factor 3	0.043
Cd40	CD40 antigen	0.043
Duox2	dual oxidase 2	0.043
Pabpc2	poly(A) binding protein, cytoplasmic 2	0.043
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.043
Efnb1	ephrin B1	0.043
Ets2	E26 avian leukemia oncogene 2, 3' domain	0.043
Hsd17b4	hydroxysteroid (17-beta) dehydrogenase 4	0.042
Clock	circadian locomotor output cycles kaput	0.042
Nkx2-6	NK2 transcription factor related, locus 6 (Drosophila)	0.042
Igfals	insulin-like growth factor binding protein, acid labile subunit	0.042
Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.042
Padi3	peptidyl arginine deiminase, type III	0.042
Timp3	tissue inhibitor of metalloproteinase 3	0.042
Hoxa10	homeobox A10	0.041
Wnt9b	wingless-type MMTV integration site 9B	0.041
Tle1	transducin-like enhancer of split 1, homolog of Drosophila E(spl)	0.041
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.041
Cfh	complement component factor h	0.041
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.041
Scmh1	sex comb on midleg homolog 1	0.041
Gjb1	gap junction protein, beta 1	0.041
Uhrf1	ubiquitin-like, containing PHD and RING finger domains, 1	0.041
Ncoa1	nuclear receptor coactivator 1	0.041
Gdf3	growth differentiation factor 3	0.040
Cdx2	caudal type homeobox 2	0.040
Akap9	A kinase (PRKA) anchor protein (yotiao) 9	0.040
Hsd17b2	hydroxysteroid (17-beta) dehydrogenase 2	0.040
Ngf	nerve growth factor	0.040
Syt9	synaptotagmin IX	0.040
Cfc1	cripto, FRL-1, cryptic family 1	0.040
Serpina12	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12	0.040
Tbx15	T-box 15	0.040
Hmx1	H6 homeobox 1	0.040
Ppap2b	phosphatidic acid phosphatase type 2B	0.040
Klf3	Kruppel-like factor 3 (basic)	0.040	Mouse
Esr1	estrogen receptor 1 (alpha)	0.040
Kdm5b	lysine (K)-specific demethylase 5B	0.040
Med1	mediator complex subunit 1	0.040
Cux1	cut-like homeobox 1	0.040	Mouse
Foxp1	forkhead box P1	0.040
Echs1	enoyl Coenzyme A hydratase, short chain, 1, mitochondrial	0.039
Pcdh12	protocadherin 12	0.039
Ep300	E1A binding protein p300	0.039
Tgfbr1	transforming growth factor, beta receptor I	0.039
Slc40a1	solute carrier family 40 (iron-regulated transporter), member 1	0.039
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.039
P2ry1	purinergic receptor P2Y, G-protein coupled 1	0.039
Prodh2	proline dehydrogenase (oxidase) 2	0.039
Ash1l	ash1 (absent, small, or homeotic)-like (Drosophila)	0.039
Crhr2	corticotropin releasing hormone receptor 2	0.039
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.039
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.039
Thbd	thrombomodulin	0.039
Mybl2	myeloblastosis oncogene-like 2	0.039
Fut1	fucosyltransferase 1	0.039
Klhl24	kelch-like 24 (Drosophila)	0.038
Ccdc96	coiled-coil domain containing 96	0.038
Thrb	thyroid hormone receptor beta	0.038
Frmd6	FERM domain containing 6	0.038
Il6st	interleukin 6 signal transducer	0.038
Barx1	BarH-like homeobox 1	0.038	Mouse
Tacr2	tachykinin receptor 2	0.038
Lag3	lymphocyte-activation gene 3	0.038
Hibadh	3-hydroxyisobutyrate dehydrogenase	0.037
Rbms1	RNA binding motif, single stranded interacting protein 1	0.037
Pkd2	polycystic kidney disease 2	0.037
Gata5	GATA binding protein 5	0.037	Zebrafish Mouse
Prdm16	PR domain containing 16	0.037
Gorasp2	golgi reassembly stacking protein 2	0.037
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.037
Hadh	hydroxyacyl-Coenzyme A dehydrogenase	0.037
Mcl1	myeloid cell leukemia sequence 1	0.037
Tead4	TEA domain family member 4	0.037
Zfp148	zinc finger protein 148	0.037
Runx3	runt related transcription factor 3	0.037	Mouse
Zmym2	zinc finger, MYM-type 2	0.037
Shroom1	shroom family member 1	0.037
Hoxd9	homeobox D9	0.037
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.037
Myb	myeloblastosis oncogene	0.036
Atp2b1	ATPase, Ca++ transporting, plasma membrane 1	0.036
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.036
Lyz2	lysozyme 2	0.036
Rara	retinoic acid receptor, alpha	0.036	Zebrafish
March7	membrane-associated ring finger (C3HC4) 7	0.036
Mbl2	mannose-binding lectin (protein C) 2	0.036
Gsk3b	glycogen synthase kinase 3 beta	0.036
Kdm6b	KDM1 lysine (K)-specific demethylase 6B	0.036
Ltbp4	latent transforming growth factor beta binding protein 4	0.036
Hoxa5	homeobox A5	0.036
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.036
Twist1	twist homolog 1 (Drosophila)	0.036
Ankhd1	ankyrin repeat and KH domain containing 1	0.036
Cyp2s1	cytochrome P450, family 2, subfamily s, polypeptide 1	0.036
Klc1	kinesin light chain 1	0.036
Gsc	goosecoid homeobox	0.036
Lhx5	LIM homeobox protein 5	0.036
Mgat3	mannoside acetylglucosaminyltransferase 3	0.036
Mysm1	myb-like, SWIRM and MPN domains 1	0.036
Tenc1	tensin like C1 domain-containing phosphatase	0.036
Foxq1	forkhead box Q1	0.036
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.036
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.036
Fzd7	frizzled homolog 7 (Drosophila)	0.035	Mouse
Msx3	homeobox, msh-like 3	0.035
Eda	ectodysplasin-A	0.035
Arnt	aryl hydrocarbon receptor nuclear translocator	0.035
Tab2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.035
Lbp	lipopolysaccharide binding protein	0.035
Padi1	peptidyl arginine deiminase, type I	0.035
Rab17	RAB17, member RAS oncogene family	0.035
Ift88	intraflagellar transport 88 homolog (Chlamydomonas)	0.035
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.035
Chpt1	choline phosphotransferase 1	0.035
Ptprb	protein tyrosine phosphatase, receptor type, B	0.034
Tcfap2c	transcription factor AP-2, gamma	0.034
Retsat	retinol saturase (all trans retinol 13,14 reductase)	0.034
Xpo6	exportin 6	0.034
Meox1	mesenchyme homeobox 1	0.034
Sdha	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	0.034
Sfpi1	SFFV proviral integration 1	0.034
Capn9	calpain 9	0.034
Foxa3	forkhead box A3	0.034	Rat
Dnahc5	dynein, axonemal, heavy chain 5	0.034
Tdgf1	teratocarcinoma-derived growth factor 1	0.034	Mouse
Tcf12	transcription factor 12	0.034
Hivep2	human immunodeficiency virus type I enhancer binding protein 2	0.034
Idh1	isocitrate dehydrogenase 1 (NADP+), soluble	0.034
Traf2	TNF receptor-associated factor 2	0.034
Pdpk1	3-phosphoinositide dependent protein kinase 1	0.034
Jag2	jagged 2	0.033	Zebrafish
Rasip1	Ras interacting protein 1	0.033
Pbld2	phenazine biosynthesis-like protein domain containing 2	0.033
Stat5a	signal transducer and activator of transcription 5A	0.033
Stk4	serine/threonine kinase 4	0.033
Dusp1	dual specificity phosphatase 1	0.033
Zfp503	zinc finger protein 503	0.033
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.033
Cp	ceruloplasmin	0.033
Serpina5	serine (or cysteine) peptidase inhibitor, clade A, member 5	0.033
Rag1	recombination activating gene 1	0.033
Fam151a	family with sequence simliarity 151, member A	0.033
Pan3	PAN3 polyA specific ribonuclease subunit homolog (S. cerevisiae)	0.033
Tbx20	T-box 20	0.033
Vipr1	vasoactive intestinal peptide receptor 1	0.033
Myadm	myeloid-associated differentiation marker	0.033
Tnip1	TNFAIP3 interacting protein 1	0.033
Uncx	UNC homeobox	0.033
Nfia	nuclear factor I/A	0.033
Met	met proto-oncogene	0.033
Copg	coatomer protein complex, subunit gamma	0.032
Bcl6	B-cell leukemia/lymphoma 6	0.032
Hamp	hepcidin antimicrobial peptide	0.032
Fgf18	fibroblast growth factor 18	0.032
Ikbkg	inhibitor of kappaB kinase gamma	0.032
Eif2ak3	eukaryotic translation initiation factor 2 alpha kinase 3	0.032
Tnks1bp1	tankyrase 1 binding protein 1	0.032
Mfap2	microfibrillar-associated protein 2	0.032
Cpn1	carboxypeptidase N, polypeptide 1	0.032	Zebrafish
Smagp	small cell adhesion glycoprotein	0.032
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.032
Hoxb5	homeobox B5	0.032
Anxa8	annexin A8	0.032
Pltp	phospholipid transfer protein	0.032
Il2	interleukin 2	0.032
Phyh	phytanoyl-CoA hydroxylase	0.032
B4galnt2	beta-1,4-N-acetyl-galactosaminyl transferase 2	0.032
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.032
Ets1	E26 avian leukemia oncogene 1, 5' domain	0.032
Socs1	suppressor of cytokine signaling 1	0.031
Des	desmin	0.031
Zeb1	zinc finger E-box binding homeobox 1	0.031
Elk3	ELK3, member of ETS oncogene family	0.031
Mll3	myeloid/lymphoid or mixed-lineage leukemia 3	0.031
Ttc7	tetratricopeptide repeat domain 7	0.031
Efna4	ephrin A4	0.031
Gata1	GATA binding protein 1	0.031	Mouse
Aldh6a1	aldehyde dehydrogenase family 6, subfamily A1	0.031
Cilp2	cartilage intermediate layer protein 2	0.031
Cyld	cylindromatosis (turban tumor syndrome)	0.031
Egr1	early growth response 1	0.031
Tnf	tumor necrosis factor	0.031	Zebrafish
Mecp2	methyl CpG binding protein 2	0.031
Pzp	pregnancy zone protein	0.031	Zebrafish
Fhl3	four and a half LIM domains 3	0.031	Mouse
Rsf1	remodeling and spacing factor 1	0.031
Inhba	inhibin beta-A	0.031
Med13l	mediator complex subunit 13-like	0.031
Cacna1a	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.031
Dlk1	delta-like 1 homolog (Drosophila)	0.031
Irx4	Iroquois related homeobox 4 (Drosophila)	0.031
Rgn	regucalcin	0.030
Fgf5	fibroblast growth factor 5	0.030
Rest	RE1-silencing transcription factor	0.030
Ednrb	endothelin receptor type B	0.030
Hif3a	hypoxia inducible factor 3, alpha subunit	0.030
Dyx1c1	dyslexia susceptibility 1 candidate 1 homolog (human)	0.030
Ncs1	neuronal calcium sensor 1	0.030
Aifm1	apoptosis-inducing factor, mitochondrion-associated 1	0.030
Dlx3	distal-less homeobox 3	0.030
Plau	plasminogen activator, urokinase	0.030	Mouse Rat
Mrvi1	MRV integration site 1	0.030
Lama1	laminin, alpha 1	0.030
Trp63	transformation related protein 63	0.030
Slc4a8	solute carrier family 4 (anion exchanger), member 8	0.030
Hoxb13	homeobox B13	0.030
Scd1	stearoyl-Coenzyme A desaturase 1	0.030
Cd19	CD19 antigen	0.030
Pcsk4	proprotein convertase subtilisin/kexin type 4	0.030
Dmc1	DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)	0.030
Sykb	spleen tyrosine kinase	0.030
Fut7	fucosyltransferase 7	0.030
Robo3	roundabout homolog 3 (Drosophila)	0.030
Cbfa2t3	core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)	0.030
Srebf2	sterol regulatory element binding factor 2	0.030
Fn1	fibronectin 1	0.030
Hspa5	heat shock protein 5	0.030
Prss39	protease, serine, 39	0.030
Alkbh1	alkB, alkylation repair homolog 1 (E. coli)	0.030
Igf1r	insulin-like growth factor I receptor	0.030
Ikbkb	inhibitor of kappaB kinase beta	0.030
Ift81	intraflagellar transport 81 homolog (Chlamydomonas)	0.030
Dmrtb1	DMRT-like family B with proline-rich C-terminal, 1	0.030
Anpep	alanyl (membrane) aminopeptidase	0.030
Stra6	stimulated by retinoic acid gene 6	0.030
Cyp2d10	cytochrome P450, family 2, subfamily d, polypeptide 10	0.029
Alb	albumin	0.029
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.029
Qdpr	quinoid dihydropteridine reductase	0.029	Rat
Slc34a2	solute carrier family 34 (sodium phosphate), member 2	0.029
Plac1	placental specific protein 1	0.029
Cldn6	claudin 6	0.029
Fgg	fibrinogen gamma chain	0.029
Chd2	chromodomain helicase DNA binding protein 2	0.029
Hpn	hepsin	0.029	Human
Dmrt1	doublesex and mab-3 related transcription factor 1	0.029
Amotl2	angiomotin-like 2	0.029
Insm1	insulinoma-associated 1	0.029
Sp4	trans-acting transcription factor 4	0.029	Mouse
Efhd2	EF hand domain containing 2	0.029
Psen1	presenilin 1	0.029
Apom	apolipoprotein M	0.029
Pyy	peptide YY	0.029
Arhgef25	Rho guanine nucleotide exchange factor (GEF) 25	0.029
Atoh8	atonal homolog 8 (Drosophila)	0.029
Hdac4	histone deacetylase 4	0.029
Nrg3	neuregulin 3	0.029
Tm9sf2	transmembrane 9 superfamily member 2	0.029
Mut	methylmalonyl-Coenzyme A mutase	0.029
Upk3b	uroplakin 3B	0.029
Epb4.1l4b	erythrocyte protein band 4.1-like 4b	0.028
Dmtf1	cyclin D binding myb-like transcription factor 1	0.028
Apof	apolipoprotein F	0.028
Map3k1	mitogen-activated protein kinase kinase kinase 1	0.028
Rora	RAR-related orphan receptor alpha	0.028
Hnf1b	HNF1 homeobox B	0.028
Tpbg	trophoblast glycoprotein	0.028
Neurog3	neurogenin 3	0.028
Zfp358	zinc finger protein 358	0.028
Cdh6	cadherin 6	0.028
Trfr2	transferrin receptor 2	0.028
Figla	folliculogenesis specific basic helix-loop-helix	0.028
Fcna	ficolin A	0.028
Smarcc2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	0.028
Plcd1	phospholipase C, delta 1	0.028
Emid2	EMI domain containing 2	0.028
Pla2g2a	phospholipase A2, group IIA (platelets, synovial fluid)	0.028
Epha1	Eph receptor A1	0.028
Nfatc3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	0.028
Rbp2	retinol binding protein 2, cellular	0.028
Ephb3	Eph receptor B3	0.028
Tulp2	tubby-like protein 2	0.028
F2r	coagulation factor II (thrombin) receptor	0.028
Wwtr1	WW domain containing transcription regulator 1	0.028
Mmp9	matrix metallopeptidase 9	0.028
Nrk	Nik related kinase	0.028
Proc	protein C	0.028
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.027
Sh3rf1	SH3 domain containing ring finger 1	0.027
E2f8	E2F transcription factor 8	0.027
Eya4	eyes absent 4 homolog (Drosophila)	0.027
Nbl1	neuroblastoma, suppression of tumorigenicity 1	0.027
Bnc1	basonuclin 1	0.027
Igbp1b	immunoglobulin (CD79A) binding protein 1b	0.027
Alx1	ALX homeobox 1	0.027
Npas2	neuronal PAS domain protein 2	0.027
Mnx1	motor neuron and pancreas homeobox 1	0.027
Ctdsp2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2	0.027
Ptprf	protein tyrosine phosphatase, receptor type, F	0.027
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.027
Id2	inhibitor of DNA binding 2	0.027
Ern2	endoplasmic reticulum (ER) to nucleus signalling 2	0.027
Edar	ectodysplasin-A receptor	0.027
Asah1	N-acylsphingosine amidohydrolase 1	0.027
Fzd2	frizzled homolog 2 (Drosophila)	0.027	Mouse
Braf	Braf transforming gene	0.027
Cdadc1	cytidine and dCMP deaminase domain containing 1	0.027
Edem1	ER degradation enhancer, mannosidase alpha-like 1	0.027
Thbs1	thrombospondin 1	0.027
Cd70	CD70 antigen	0.027
Muc13	mucin 13, epithelial transmembrane	0.027
Msc	musculin	0.027
Prox1	prospero-related homeobox 1	0.027
Etv2	ets variant gene 2	0.027
Iqgap1	IQ motif containing GTPase activating protein 1	0.027
Mxd3	Max dimerization protein 3	0.027
Lef1	lymphoid enhancer binding factor 1	0.026
Adrb3	adrenergic receptor, beta 3	0.026
Hoxc4	homeobox C4	0.026
Maf	avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog	0.026
Ramp2	receptor (calcitonin) activity modifying protein 2	0.026
Usp43	ubiquitin specific peptidase 43	0.026
Myod1	myogenic differentiation 1	0.026
Grb10	growth factor receptor bound protein 10	0.026
Efna1	ephrin A1	0.026
Esr2	estrogen receptor 2 (beta)	0.026
Rfx7	regulatory factor X, 7	0.026
Ocln	occludin	0.026
Arx	aristaless related homeobox	0.026
Scp2	sterol carrier protein 2, liver	0.026
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.026
Acadm	acyl-Coenzyme A dehydrogenase, medium chain	0.026
Bok	BCL2-related ovarian killer protein	0.026
Hmgcs2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2	0.026
Cxadr	coxsackie virus and adenovirus receptor	0.026
Jmjd1c	jumonji domain containing 1C	0.026
Ptgs1	prostaglandin-endoperoxide synthase 1	0.026
Bckdhb	branched chain ketoacid dehydrogenase E1, beta polypeptide	0.026
Fbln1	fibulin 1	0.026
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.026
Tgfb1i1	transforming growth factor beta 1 induced transcript 1	0.026	Mouse
Slc6a12	solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12	0.026
Ptpru	protein tyrosine phosphatase, receptor type, U	0.026
Myl7	myosin, light polypeptide 7, regulatory	0.026
Edn2	endothelin 2	0.026
Cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	0.026
Bcl6b	B-cell CLL/lymphoma 6, member B	0.025
Lnpep	leucyl/cystinyl aminopeptidase	0.025
Hoxb9	homeobox B9	0.025
Cldn7	claudin 7	0.025
Dll3	delta-like 3 (Drosophila)	0.025
Dlg1	discs, large homolog 1 (Drosophila)	0.025
Rel	reticuloendotheliosis oncogene	0.025	Mouse
Fgf17	fibroblast growth factor 17	0.025
Fbxl3	F-box and leucine-rich repeat protein 3	0.025
Gata2	GATA binding protein 2	0.025	Mouse
Polr2a	polymerase (RNA) II (DNA directed) polypeptide A	0.025
Il6ra	interleukin 6 receptor, alpha	0.025
Hoxa6	homeobox A6	0.025
Tert	telomerase reverse transcriptase	0.025
Atm	ataxia telangiectasia mutated homolog (human)	0.025
Rspo1	R-spondin homolog (Xenopus laevis)	0.025
Sult1b1	sulfotransferase family 1B, member 1	0.025
Atp4a	ATPase, H+/K+ exchanging, gastric, alpha polypeptide	0.025
Rb1cc1	RB1-inducible coiled-coil 1	0.025