Process View
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "mitotic spindle organization"
Name | Description | Probability | Func Analog Organism | |
---|---|---|---|---|
Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.959 | Worm | |
Ccna2 | cyclin A2 | 0.610 | ||
Ccnb1 | cyclin B1 | 0.536 | Human Yeast | |
Cct7 | chaperonin containing Tcp1, subunit 7 (eta) | 0.488 | Fly | |
Hspa8 | heat shock protein 8 | 0.476 | ||
Mis18bp1 | MIS18 binding protein 1 | 0.407 | ||
Plk4 | polo-like kinase 4 (Drosophila) | 0.398 | Fly | |
Nde1 | nuclear distribution gene E homolog 1 (A nidulans) | 0.391 | Fly | |
Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.389 | ||
Cdk1 | cyclin-dependent kinase 1 | 0.349 | ||
Trp53 | transformation related protein 53 | 0.347 | ||
Rrm1 | ribonucleotide reductase M1 | 0.346 | ||
Kif20a | kinesin family member 20A | 0.328 | Worm | |
Kif2c | kinesin family member 2C | 0.319 | Fly | |
Psmd4 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | 0.319 | ||
Kif11 | kinesin family member 11 | 0.312 | Human Worm Fly | |
Hmmr | hyaluronan mediated motility receptor (RHAMM) | 0.281 | ||
Apc | adenomatosis polyposis coli | 0.269 | Worm | |
Kif4 | kinesin family member 4 | 0.258 | Worm Fly | |
Tgfb1 | transforming growth factor, beta 1 | 0.256 | ||
Rpgrip1l | Rpgrip1-like | 0.239 | ||
Axin1 | axin 1 | 0.235 | Worm | |
Nek2 | NIMA (never in mitosis gene a)-related expressed kinase 2 | 0.235 | ||
Smc4 | structural maintenance of chromosomes 4 | 0.225 | ||
Ckap2 | cytoskeleton associated protein 2 | 0.220 | ||
Lef1 | lymphoid enhancer binding factor 1 | 0.214 | Worm | |
Cct6a | chaperonin containing Tcp1, subunit 6a (zeta) | 0.210 | ||
Smu1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) | 0.206 | ||
Cdc20 | cell division cycle 20 homolog (S. cerevisiae) | 0.201 | ||
Tmpo | thymopoietin | 0.197 | ||
Prc1 | protein regulator of cytokinesis 1 | 0.190 | Worm Fly | |
Mcm7 | minichromosome maintenance deficient 7 (S. cerevisiae) | 0.184 | ||
Cct5 | chaperonin containing Tcp1, subunit 5 (epsilon) | 0.179 | Fly | |
Aurkb | aurora kinase B | 0.178 | Human Fly | |
Pten | phosphatase and tensin homolog | 0.176 | ||
Plk1 | polo-like kinase 1 (Drosophila) | 0.167 | Worm Fly | |
Gsk3b | glycogen synthase kinase 3 beta | 0.139 | Worm | |
Spag5 | sperm associated antigen 5 | 0.138 | ||
Racgap1 | Rac GTPase-activating protein 1 | 0.132 | Human Fly | |
Ran | RAN, member RAS oncogene family | 0.131 | ||
Dlgap5 | discs, large (Drosophila) homolog-associated protein 5 | 0.122 | ||
Lmnb1 | lamin B1 | 0.120 | ||
Ezh2 | enhancer of zeste homolog 2 (Drosophila) | 0.117 | ||
Ncaph | non-SMC condensin I complex, subunit H | 0.116 | Fly | |
Bub1b | budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) | 0.107 | Fly | |
Meox2 | mesenchyme homeobox 2 | 0.102 | ||
Anln | anillin, actin binding protein | 0.102 | ||
Smc1a | structural maintenance of chromosomes 1A | 0.101 | ||
Top2a | topoisomerase (DNA) II alpha | 0.098 | ||
Psmc3 | proteasome (prosome, macropain) 26S subunit, ATPase 3 | 0.098 | ||
Asf1b | ASF1 anti-silencing function 1 homolog B (S. cerevisiae) | 0.098 | ||
Kif22 | kinesin family member 22 | 0.098 | ||
Pkd1 | polycystic kidney disease 1 homolog | 0.095 | ||
Cct3 | chaperonin containing Tcp1, subunit 3 (gamma) | 0.094 | Fly | |
Stag1 | stromal antigen 1 | 0.092 | ||
Pafah1b1 | platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 | 0.082 | Worm | |
Hsp90ab1 | heat shock protein 90 alpha (cytosolic), class B member 1 | 0.080 | Fly | |
Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.077 | ||
Nf1 | neurofibromatosis 1 | 0.076 | ||
Fgfr1 | fibroblast growth factor receptor 1 | 0.074 | ||
Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.073 | ||
Msh2 | mutS homolog 2 (E. coli) | 0.070 | ||
Csf1 | colony stimulating factor 1 (macrophage) | 0.070 | ||
Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.067 | ||
Kif23 | kinesin family member 23 | 0.067 | Human Worm Fly | |
Ppp1ca | protein phosphatase 1, catalytic subunit, alpha isoform | 0.067 | ||
Hnrnpab | heterogeneous nuclear ribonucleoprotein A/B | 0.067 | ||
Mybl2 | myeloblastosis oncogene-like 2 | 0.065 | ||
Vangl1 | vang-like 1 (van gogh, Drosophila) | 0.064 | ||
D2Ertd750e | DNA segment, Chr 2, ERATO Doi 750, expressed | 0.061 | ||
Cdk4 | cyclin-dependent kinase 4 | 0.060 | ||
Brca1 | breast cancer 1 | 0.060 | ||
Pik3ca | phosphatidylinositol 3-kinase, catalytic, alpha polypeptide | 0.059 | ||
Ccnb2 | cyclin B2 | 0.059 | Yeast | |
Stip1 | stress-induced phosphoprotein 1 | 0.059 | ||
Tcp1 | t-complex protein 1 | 0.059 | Fly | |
Ywhaz | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.057 | ||
Rad21 | RAD21 homolog (S. pombe) | 0.055 | ||
Hsp90aa1 | heat shock protein 90, alpha (cytosolic), class A member 1 | 0.055 | Fly | |
Rb1 | retinoblastoma 1 | 0.051 | ||
Kdr | kinase insert domain protein receptor | 0.051 | Fly | |
Plcg2 | phospholipase C, gamma 2 | 0.051 | ||
Usp9x | ubiquitin specific peptidase 9, X chromosome | 0.050 | ||
Ywhae | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 0.048 | ||
Elavl1 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) | 0.048 | ||
Rad51ap1 | RAD51 associated protein 1 | 0.045 | ||
Tacc3 | transforming, acidic coiled-coil containing protein 3 | 0.044 | ||
Kif3a | kinesin family member 3A | 0.043 | ||
Nuf2 | NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae) | 0.043 | ||
Eif3a | eukaryotic translation initiation factor 3, subunit A | 0.042 | Fly | |
Cenpn | centromere protein N | 0.039 | ||
Abl1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.039 | ||
Anp32e | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.038 | ||
Ccnf | cyclin F | 0.037 | ||
Ppp2r1a | protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform | 0.037 | ||
Ttk | Ttk protein kinase | 0.037 | ||
Bub1 | budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) | 0.036 | ||
Psmc2 | proteasome (prosome, macropain) 26S subunit, ATPase 2 | 0.036 | ||
Cdc25c | cell division cycle 25 homolog C (S. pombe) | 0.035 | ||
Ect2 | ect2 oncogene | 0.034 | ||
Aspm | asp (abnormal spindle)-like, microcephaly associated (Drosophila) | 0.033 | Fly | |
Foxm1 | forkhead box M1 | 0.033 | ||
Tubb5 | tubulin, beta 5 | 0.033 | ||
Eif4g1 | eukaryotic translation initiation factor 4, gamma 1 | 0.033 | ||
Cdca5 | cell division cycle associated 5 | 0.032 | ||
Ranbp1 | RAN binding protein 1 | 0.032 | ||
Sae1 | SUMO1 activating enzyme subunit 1 | 0.032 | ||
Rrm2 | ribonucleotide reductase M2 | 0.032 | ||
Pik3r1 | phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) | 0.031 | ||
Stil | Scl/Tal1 interrupting locus | 0.031 | Human Zebrafish | |
Zeb1 | zinc finger E-box binding homeobox 1 | 0.031 | ||
Eif3b | eukaryotic translation initiation factor 3, subunit B | 0.031 | ||
Pbk | PDZ binding kinase | 0.031 | ||
Birc5 | baculoviral IAP repeat-containing 5 | 0.031 | ||
Ccdc99 | coiled-coil domain containing 99 | 0.030 | ||
Notch1 | Notch gene homolog 1 (Drosophila) | 0.030 | ||
Psen1 | presenilin 1 | 0.029 | ||
Psmc5 | protease (prosome, macropain) 26S subunit, ATPase 5 | 0.029 | ||
Smad7 | MAD homolog 7 (Drosophila) | 0.028 | ||
Tcf7 | transcription factor 7, T-cell specific | 0.028 | Worm | |
Invs | inversin | 0.028 | ||
Fam54a | family with sequence similarity 54, member A | 0.027 | ||
Rpl7a | ribosomal protein L7A | 0.027 | ||
Ube2c | ubiquitin-conjugating enzyme E2C | 0.027 | ||
Psmd14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.027 | ||
Ptk2 | PTK2 protein tyrosine kinase 2 | 0.026 | ||
Rac1 | RAS-related C3 botulinum substrate 1 | 0.026 | ||
Cenpe | centromere protein E | 0.026 | ||
1110004F10Rik | RIKEN cDNA 1110004F10 gene | 0.026 | ||
Ptch1 | patched homolog 1 | 0.026 | ||
Rpl11 | ribosomal protein L11 | 0.025 | ||
Ptprq | protein tyrosine phosphatase, receptor type, Q | 0.025 | ||
Ccnd1 | cyclin D1 | 0.024 | ||
Skp1a | S-phase kinase-associated protein 1A | 0.024 | ||
Pcna | proliferating cell nuclear antigen | 0.024 | Fly | |
Psmd6 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | 0.024 | ||
Cenph | centromere protein H | 0.023 | ||
Myh9 | myosin, heavy polypeptide 9, non-muscle | 0.023 | ||
Notch2 | Notch gene homolog 2 (Drosophila) | 0.023 | ||
Cacybp | calcyclin binding protein | 0.023 | ||
Fam64a | family with sequence similarity 64, member A | 0.023 | ||
Ppp1cc | protein phosphatase 1, catalytic subunit, gamma isoform | 0.023 | Fly | |
Nop58 | NOP58 ribonucleoprotein homolog (yeast) | 0.023 | ||
Eif3d | eukaryotic translation initiation factor 3, subunit D | 0.022 | ||
Macf1 | microtubule-actin crosslinking factor 1 | 0.022 | ||
Psmb6 | proteasome (prosome, macropain) subunit, beta type 6 | 0.022 | ||
Iqgap3 | IQ motif containing GTPase activating protein 3 | 0.022 | ||
Ppih | peptidyl prolyl isomerase H | 0.021 | ||
Gltscr2 | glioma tumor suppressor candidate region gene 2 | 0.021 | ||
Rbm8a | RNA binding motif protein 8a | 0.021 | ||
Chordc1 | cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1 | 0.020 | ||
Diap3 | diaphanous homolog 3 (Drosophila) | 0.020 | ||
Stat6 | signal transducer and activator of transcription 6 | 0.020 | ||
Mcm3 | minichromosome maintenance deficient 3 (S. cerevisiae) | 0.020 | ||
Strn3 | striatin, calmodulin binding protein 3 | 0.020 | ||
Nap1l1 | nucleosome assembly protein 1-like 1 | 0.020 | ||
Melk | maternal embryonic leucine zipper kinase | 0.020 | ||
Ndc80 | NDC80 homolog, kinetochore complex component (S. cerevisiae) | 0.020 | Human | |
Tra2b | transformer 2 beta homolog (Drosophila) | 0.019 | ||
Syncrip | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.019 | ||
Cep55 | centrosomal protein 55 | 0.019 | ||
Hif1a | hypoxia inducible factor 1, alpha subunit | 0.019 | ||
Mgea5 | meningioma expressed antigen 5 (hyaluronidase) | 0.019 | ||
Smc2 | structural maintenance of chromosomes 2 | 0.018 | Fly | |
Smad3 | MAD homolog 3 (Drosophila) | 0.018 | ||
Cdkn3 | cyclin-dependent kinase inhibitor 3 | 0.018 | ||
Ndel1 | nuclear distribution gene E-like homolog 1 (A. nidulans) | 0.018 | ||
Hsph1 | heat shock 105kDa/110kDa protein 1 | 0.018 | ||
Srsf1 | serine/arginine-rich splicing factor 1 | 0.018 | ||
Ooep | oocyte expressed protein homolog (dog) | 0.018 | ||
Nup93 | nucleoporin 93 | 0.017 | ||
Psmb7 | proteasome (prosome, macropain) subunit, beta type 7 | 0.017 | ||
Psmc4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 0.017 | ||
Cbl | Casitas B-lineage lymphoma | 0.017 | ||
Vhl | von Hippel-Lindau tumor suppressor | 0.017 | Fly | |
2810417H13Rik | RIKEN cDNA 2810417H13 gene | 0.017 | ||
Flii | flightless I homolog (Drosophila) | 0.017 | ||
Ctcf | CCCTC-binding factor | 0.016 | ||
Usp1 | ubiquitin specific peptidase 1 | 0.016 | ||
Stk11 | serine/threonine kinase 11 | 0.016 | Fly | |
Lbr | lamin B receptor | 0.016 | ||
Rad18 | RAD18 homolog (S. cerevisiae) | 0.016 | ||
Ncapg | non-SMC condensin I complex, subunit G | 0.016 | ||
Cct2 | chaperonin containing Tcp1, subunit 2 (beta) | 0.016 | Fly | |
Psmb4 | proteasome (prosome, macropain) subunit, beta type 4 | 0.016 | ||
Runx2 | runt related transcription factor 2 | 0.016 | ||
Sfpq | splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) | 0.015 | ||
Psmd12 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 0.015 | ||
Kif5b | kinesin family member 5B | 0.015 | ||
Spnb2 | spectrin beta 2 | 0.015 | ||
Psma1 | proteasome (prosome, macropain) subunit, alpha type 1 | 0.015 | ||
Mki67 | antigen identified by monoclonal antibody Ki 67 | 0.015 | ||
Mns1 | meiosis-specific nuclear structural protein 1 | 0.015 | ||
C330027C09Rik | RIKEN cDNA C330027C09 gene | 0.015 | ||
Mastl | microtubule associated serine/threonine kinase-like | 0.015 | ||
Ikzf1 | IKAROS family zinc finger 1 | 0.015 | ||
Il6st | interleukin 6 signal transducer | 0.015 | ||
Nf2 | neurofibromatosis 2 | 0.015 | ||
Fmr1 | fragile X mental retardation syndrome 1 homolog | 0.015 | ||
Psma6 | proteasome (prosome, macropain) subunit, alpha type 6 | 0.015 | ||
Prkar1a | protein kinase, cAMP dependent regulatory, type I, alpha | 0.015 | ||
Ckap5 | cytoskeleton associated protein 5 | 0.015 | ||
Bicc1 | bicaudal C homolog 1 (Drosophila) | 0.015 | ||
Col1a1 | collagen, type I, alpha 1 | 0.014 | ||
Nsfl1c | NSFL1 (p97) cofactor (p47) | 0.014 | ||
Prim2 | DNA primase, p58 subunit | 0.014 | ||
Foxp3 | forkhead box P3 | 0.014 | ||
Ssrp1 | structure specific recognition protein 1 | 0.014 | ||
Gtse1 | G two S phase expressed protein 1 | 0.014 | ||
Msn | moesin | 0.014 | Fly | |
Rcc2 | regulator of chromosome condensation 2 | 0.014 | ||
U2af1 | U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1 | 0.014 | Fly | |
Prkce | protein kinase C, epsilon | 0.014 | ||
Vegfc | vascular endothelial growth factor C | 0.014 | ||
Cbx5 | chromobox homolog 5 (Drosophila HP1a) | 0.014 | ||
Hars | histidyl-tRNA synthetase | 0.014 | ||
Ska1 | spindle and kinetochore associated complex subunit 1 | 0.014 | ||
Usp33 | ubiquitin specific peptidase 33 | 0.014 | ||
Nup43 | nucleoporin 43 | 0.014 | ||
Fzr1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.014 | ||
Spna2 | spectrin alpha 2 | 0.014 | ||
Hnrnpf | heterogeneous nuclear ribonucleoprotein F | 0.014 | ||
Magoh | mago-nashi homolog, proliferation-associated (Drosophila) | 0.014 | ||
Cenpf | centromere protein F | 0.013 | ||
Sass6 | spindle assembly 6 homolog (C. elegans) | 0.013 | Fly | |
Chek1 | checkpoint kinase 1 homolog (S. pombe) | 0.013 | ||
Epas1 | endothelial PAS domain protein 1 | 0.013 | ||
Cdk2 | cyclin-dependent kinase 2 | 0.013 | ||
Exo1 | exonuclease 1 | 0.013 | ||
Ddx1 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 | 0.013 | ||
Ruvbl2 | RuvB-like protein 2 | 0.013 | ||
Dtl | denticleless homolog (Drosophila) | 0.013 | ||
Map3k3 | mitogen-activated protein kinase kinase kinase 3 | 0.012 | ||
Cpsf2 | cleavage and polyadenylation specific factor 2 | 0.012 | ||
Sox9 | SRY-box containing gene 9 | 0.012 | ||
Myef2 | myelin basic protein expression factor 2, repressor | 0.012 | ||
Tcf19 | transcription factor 19 | 0.012 | ||
Sgol1 | shugoshin-like 1 (S. pombe) | 0.012 | ||
Pole2 | polymerase (DNA directed), epsilon 2 (p59 subunit) | 0.012 | ||
Caprin1 | cell cycle associated protein 1 | 0.012 | ||
Raf1 | v-raf-leukemia viral oncogene 1 | 0.012 | ||
Xpo1 | exportin 1, CRM1 homolog (yeast) | 0.012 | ||
Depdc1a | DEP domain containing 1a | 0.012 | ||
Psma7 | proteasome (prosome, macropain) subunit, alpha type 7 | 0.012 | ||
H2afx | H2A histone family, member X | 0.012 | ||
Tmem48 | transmembrane protein 48 | 0.012 | ||
Tpx2 | TPX2, microtubule-associated protein homolog (Xenopus laevis) | 0.012 | ||
Rbl1 | retinoblastoma-like 1 (p107) | 0.012 | ||
Enah | enabled homolog (Drosophila) | 0.011 | ||
Cdc5l | cell division cycle 5-like (S. pombe) | 0.011 | ||
Uhrf1 | ubiquitin-like, containing PHD and RING finger domains, 1 | 0.011 | ||
Tcirg1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3 | 0.011 | ||
Cdc7 | cell division cycle 7 (S. cerevisiae) | 0.011 | ||
Flt4 | FMS-like tyrosine kinase 4 | 0.011 | Fly | |
Hnrnph1 | heterogeneous nuclear ribonucleoprotein H1 | 0.011 | ||
Lfng | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 0.011 | ||
Hnrnpr | heterogeneous nuclear ribonucleoprotein R | 0.011 | ||
Ncapd2 | non-SMC condensin I complex, subunit D2 | 0.011 | ||
Fam83d | family with sequence similarity 83, member D | 0.011 | ||
Wdr1 | WD repeat domain 1 | 0.011 | ||
Psmc3ip | proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein | 0.011 | ||
Gsg2 | germ cell-specific gene 2 | 0.011 | ||
Cse1l | chromosome segregation 1-like (S. cerevisiae) | 0.011 | ||
Smarca5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.011 | ||
Srsf3 | serine/arginine-rich splicing factor 3 | 0.011 | ||
Cdkn2c | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.011 | ||
Ubap2 | ubiquitin-associated protein 2 | 0.011 | ||
Rpl6 | ribosomal protein L6 | 0.011 | ||
Cct8 | chaperonin containing Tcp1, subunit 8 (theta) | 0.010 | ||
Trip13 | thyroid hormone receptor interactor 13 | 0.010 | ||
Kars | lysyl-tRNA synthetase | 0.010 | ||
Srrt | serrate RNA effector molecule homolog (Arabidopsis) | 0.010 | ||
Vasp | vasodilator-stimulated phosphoprotein | 0.010 | ||
Hnrnpu | heterogeneous nuclear ribonucleoprotein U | 0.010 | ||
Cdca2 | cell division cycle associated 2 | 0.010 | ||
Tcerg1 | transcription elongation regulator 1 (CA150) | 0.010 | ||
Lat | linker for activation of T cells | 0.010 | ||
Epb4.1l2 | erythrocyte protein band 4.1-like 2 | 0.010 | ||
Rbbp8 | retinoblastoma binding protein 8 | 0.010 | ||
Eme1 | essential meiotic endonuclease 1 homolog 1 (S. pombe) | 0.010 |