IMP: Integrative Multi-species Prediction

Mus musculus

50 genes annotated in mouse

innate immune response activating signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to activation or perpetuation of an innate immune response.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "innate immune response activating signal transduction"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "innate immune response activating signal transduction" (in gray)

Name	Description	Probability	Func Analog Organism
Myd88	myeloid differentiation primary response gene 88	1.000
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.999
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.999
Traf6	TNF receptor-associated factor 6	0.998	Mouse
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.997
Rtp4	receptor transporter protein 4	0.987
Parp14	poly (ADP-ribose) polymerase family, member 14	0.985
Sykb	spleen tyrosine kinase	0.968
Ddx60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.967
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.951
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.942
Igh	immunoglobulin heavy chain complex	0.942
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.935
Cd40	CD40 antigen	0.929	Zebrafish
Cd180	CD180 antigen	0.927	Mouse
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.891	Human
Ptprc	protein tyrosine phosphatase, receptor type, C	0.889
Cd19	CD19 antigen	0.889
Tnf	tumor necrosis factor	0.887
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.850	Mouse
Gnrh1	gonadotropin releasing hormone 1	0.843
Plcg2	phospholipase C, gamma 2	0.808
Mavs	mitochondrial antiviral signaling protein	0.787
Il10	interleukin 10	0.786
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.784
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.778
Trim21	tripartite motif-containing 21	0.775	Mouse
Birc3	baculoviral IAP repeat-containing 3	0.769
Esr1	estrogen receptor 1 (alpha)	0.769
Ikzf1	IKAROS family zinc finger 1	0.762
Axl	AXL receptor tyrosine kinase	0.739	Mouse
Pyhin1	pyrin and HIN domain family, member 1	0.729
Cd44	CD44 antigen	0.712
Tlr4	toll-like receptor 4	0.695
Icos	inducible T-cell co-stimulator	0.695
Grb2	growth factor receptor bound protein 2	0.685
Pik3ap1	phosphoinositide-3-kinase adaptor protein 1	0.685
Klra9	killer cell lectin-like receptor subfamily A, member 9	0.655
Adam19	a disintegrin and metallopeptidase domain 19 (meltrin beta)	0.627	Mouse
Unc93b1	unc-93 homolog B1 (C. elegans)	0.617
Gbp7	guanylate binding protein 7	0.614
BC013712	cDNA sequence BC013712	0.597
Il2rb	interleukin 2 receptor, beta chain	0.592
Stat1	signal transducer and activator of transcription 1	0.584
Oasl1	2'-5' oligoadenylate synthetase-like 1	0.575
Pilrb1	paired immunoglobin-like type 2 receptor beta 1	0.574
Il1rn	interleukin 1 receptor antagonist	0.564
Emr4	EGF-like module containing, mucin-like, hormone receptor-like sequence 4	0.562
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.555
Prkce	protein kinase C, epsilon	0.542
Tyro3	TYRO3 protein tyrosine kinase 3	0.541
Irak4	interleukin-1 receptor-associated kinase 4	0.538
Irgm1	immunity-related GTPase family M member 1	0.523
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.502
Pten	phosphatase and tensin homolog	0.493
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.487
Cd22	CD22 antigen	0.484
Trim30d	tripartite motif-containing 30D	0.479	Human Mouse
Myo1g	myosin IG	0.473
Tlr2	toll-like receptor 2	0.467
Arrb2	arrestin, beta 2	0.463
Ccr6	chemokine (C-C motif) receptor 6	0.462
Prkcd	protein kinase C, delta	0.447
Arrb1	arrestin, beta 1	0.446	Mouse
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.434
Mapk14	mitogen-activated protein kinase 14	0.433
Irf9	interferon regulatory factor 9	0.423	Mouse
Bcl3	B-cell leukemia/lymphoma 3	0.419	Mouse
Btk	Bruton agammaglobulinemia tyrosine kinase	0.416	Mouse
Irgm2	immunity-related GTPase family M member 2	0.400
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.395
Irf7	interferon regulatory factor 7	0.376
Cxcl9	chemokine (C-X-C motif) ligand 9	0.373
Ncr1	natural cytotoxicity triggering receptor 1	0.368
Aoah	acyloxyacyl hydrolase	0.360
Itga4	integrin alpha 4	0.358
Mefv	Mediterranean fever	0.355
Vav1	vav 1 oncogene	0.351
Fcgr4	Fc receptor, IgG, low affinity IV	0.350
Reg2	regenerating islet-derived 2	0.342	Mouse
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.334
Zbp1	Z-DNA binding protein 1	0.328
Trim30a	tripartite motif-containing 30A	0.327
Lyz2	lysozyme 2	0.327
Il2rg	interleukin 2 receptor, gamma chain	0.324
Ldb3	LIM domain binding 3	0.323
Rsad2	radical S-adenosyl methionine domain containing 2	0.321
Slfn4	schlafen 4	0.312
Prdm1	PR domain containing 1, with ZNF domain	0.305
Gab1	growth factor receptor bound protein 2-associated protein 1	0.304
Tnfaip2	tumor necrosis factor, alpha-induced protein 2	0.294
Msr1	macrophage scavenger receptor 1	0.292
Ltbr	lymphotoxin B receptor	0.290
Pilra	paired immunoglobin-like type 2 receptor alpha	0.284
Cd86	CD86 antigen	0.283
Pax8	paired box gene 8	0.281
Traf3ip2	TRAF3 interacting protein 2	0.279
Gbp3	guanylate binding protein 3	0.279
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.277
Ghr	growth hormone receptor	0.273
Cd28	CD28 antigen	0.267
Ticam1	toll-like receptor adaptor molecule 1	0.266
Kiss1	KiSS-1 metastasis-suppressor	0.263
Ifit1	interferon-induced protein with tetratricopeptide repeats 1	0.262
Rel	reticuloendotheliosis oncogene	0.255
Clec4e	C-type lectin domain family 4, member e	0.255
Adam12	a disintegrin and metallopeptidase domain 12 (meltrin alpha)	0.255	Mouse
Slpi	secretory leukocyte peptidase inhibitor	0.253
Ifi44	interferon-induced protein 44	0.251
Irak1	interleukin-1 receptor-associated kinase 1	0.244
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.242
Ifnar1	interferon (alpha and beta) receptor 1	0.241
Traf2	TNF receptor-associated factor 2	0.232	Mouse
Casp8	caspase 8	0.231
Slfn2	schlafen 2	0.230
Inpp5d	inositol polyphosphate-5-phosphatase D	0.230
Lair1	leukocyte-associated Ig-like receptor 1	0.229
Clock	circadian locomotor output cycles kaput	0.225
Cd80	CD80 antigen	0.221
Nfkbie	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.218	Mouse
Tor3a	torsin family 3, member A	0.217
Ubd	ubiquitin D	0.215
Herc6	hect domain and RLD 6	0.215
Blnk	B-cell linker	0.206
Sfpi1	SFFV proviral integration 1	0.205
Il18r1	interleukin 18 receptor 1	0.204
Mx1	myxovirus (influenza virus) resistance 1	0.203
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.202
Itgax	integrin alpha X	0.202
Igtp	interferon gamma induced GTPase	0.201
Slamf8	SLAM family member 8	0.200
Usp18	ubiquitin specific peptidase 18	0.197
Gzmk	granzyme K	0.192
Ifi47	interferon gamma inducible protein 47	0.191
Csf1	colony stimulating factor 1 (macrophage)	0.191
Cybb	cytochrome b-245, beta polypeptide	0.189
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.182	Mouse
Epsti1	epithelial stromal interaction 1 (breast)	0.181
Ifi203	interferon activated gene 203	0.180
Amhr2	anti-Mullerian hormone type 2 receptor	0.180
Trem1	triggering receptor expressed on myeloid cells 1	0.177
Irak3	interleukin-1 receptor-associated kinase 3	0.172
Naip6	NLR family, apoptosis inhibitory protein 6	0.172
Cxcl10	chemokine (C-X-C motif) ligand 10	0.171
Isg15	ISG15 ubiquitin-like modifier	0.171
Slfn1	schlafen 1	0.168
Itgal	integrin alpha L	0.168
Duox2	dual oxidase 2	0.166
Irf5	interferon regulatory factor 5	0.164	Mouse
Il7r	interleukin 7 receptor	0.162
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.162
Trem3	triggering receptor expressed on myeloid cells 3	0.162
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.162
Mcoln2	mucolipin 2	0.161
Tnfsf10	tumor necrosis factor (ligand) superfamily, member 10	0.161
Apobec1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	0.160
2010106G01Rik	RIKEN cDNA 2010106G01 gene	0.160
Ccr2	chemokine (C-C motif) receptor 2	0.160
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.159
Samhd1	SAM domain and HD domain, 1	0.157
Ncf1	neutrophil cytosolic factor 1	0.153
Irf1	interferon regulatory factor 1	0.152
Uba7	ubiquitin-like modifier activating enzyme 7	0.150
Tifa	TRAF-interacting protein with forkhead-associated domain	0.149
Gzmb	granzyme B	0.145
Tlr8	toll-like receptor 8	0.142	Mouse
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.142
Cd300lf	CD300 antigen like family member F	0.142
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.140
P2ry13	purinergic receptor P2Y, G-protein coupled 13	0.139
Fasl	Fas ligand (TNF superfamily, member 6)	0.139
Oas3	2'-5' oligoadenylate synthetase 3	0.139
Dtx3l	deltex 3-like (Drosophila)	0.138
Ptpre	protein tyrosine phosphatase, receptor type, E	0.137
BC006779	cDNA sequence BC006779	0.136
Cxcr6	chemokine (C-X-C motif) receptor 6	0.135
Reg3a	regenerating islet-derived 3 alpha	0.130	Mouse
Cmklr1	chemokine-like receptor 1	0.129
Prnp	prion protein	0.128
Stx11	syntaxin 11	0.126
Clec4d	C-type lectin domain family 4, member d	0.125
Stat2	signal transducer and activator of transcription 2	0.124
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.124
Lpxn	leupaxin	0.123
Traf3	TNF receptor-associated factor 3	0.122
Pou2af1	POU domain, class 2, associating factor 1	0.122
Igsf6	immunoglobulin superfamily, member 6	0.122
Tnip1	TNFAIP3 interacting protein 1	0.121
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.119
Oas2	2'-5' oligoadenylate synthetase 2	0.119
Abcg3	ATP-binding cassette, sub-family G (WHITE), member 3	0.119
Mcl1	myeloid cell leukemia sequence 1	0.117
Runx1	runt related transcription factor 1	0.116
Reg3g	regenerating islet-derived 3 gamma	0.116
Ptk2b	PTK2 protein tyrosine kinase 2 beta	0.115
Cd33	CD33 antigen	0.115
Nfam1	Nfat activating molecule with ITAM motif 1	0.114
Siglece	sialic acid binding Ig-like lectin E	0.113
Oasl2	2'-5' oligoadenylate synthetase-like 2	0.112
Cenpj	centromere protein J	0.109
Cmpk2	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial	0.109
Cd247	CD247 antigen	0.107
Il18rap	interleukin 18 receptor accessory protein	0.106
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.105	Mouse
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.105
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.104
Parp9	poly (ADP-ribose) polymerase family, member 9	0.103
Cyld	cylindromatosis (turban tumor syndrome)	0.102
Ccr7	chemokine (C-C motif) receptor 7	0.102
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.102
Il1f9	interleukin 1 family, member 9	0.101
Apoe	apolipoprotein E	0.101
D14Ertd668e	DNA segment, Chr 14, ERATO Doi 668, expressed	0.101
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.099	Mouse
Cbl	Casitas B-lineage lymphoma	0.099
Cd300lb	CD300 antigen like family member B	0.098
Rag2	recombination activating gene 2	0.098
Gbp2	guanylate binding protein 2	0.097
Ccr3	chemokine (C-C motif) receptor 3	0.096
Ccr9	chemokine (C-C motif) receptor 9	0.096
Olfr480	olfactory receptor 480	0.095
Muc13	mucin 13, epithelial transmembrane	0.094
Ifitm6	interferon induced transmembrane protein 6	0.094
Pdcd1lg2	programmed cell death 1 ligand 2	0.093	Mouse
H2-DMb2	histocompatibility 2, class II, locus Mb2	0.090
Btg4	B-cell translocation gene 4	0.089
Ggt5	gamma-glutamyltransferase 5	0.089
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.088
Flt3	FMS-like tyrosine kinase 3	0.088
Icam1	intercellular adhesion molecule 1	0.087
Spib	Spi-B transcription factor (Spi-1/PU.1 related)	0.086
Cxcr2	chemokine (C-X-C motif) receptor 2	0.086
Bcl6	B-cell leukemia/lymphoma 6	0.085
Eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2	0.085
Cd84	CD84 antigen	0.085
Ccl4	chemokine (C-C motif) ligand 4	0.085
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.084
Cd8a	CD8 antigen, alpha chain	0.084
Slamf7	SLAM family member 7	0.084
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.082
Plcd1	phospholipase C, delta 1	0.081
Fas	Fas (TNF receptor superfamily member 6)	0.080
Clec4n	C-type lectin domain family 4, member n	0.080
Gzma	granzyme A	0.079
Batf	basic leucine zipper transcription factor, ATF-like	0.078
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.078
Csprs	component of Sp100-rs	0.078
Ifng	interferon gamma	0.078
Ikbkg	inhibitor of kappaB kinase gamma	0.078
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.078
Cd69	CD69 antigen	0.077	Mouse
Lcp1	lymphocyte cytosolic protein 1	0.077
Il2	interleukin 2	0.076
Trim25	tripartite motif-containing 25	0.076
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.075
Dok3	docking protein 3	0.074
Sp100	nuclear antigen Sp100	0.074
Naip2	NLR family, apoptosis inhibitory protein 2	0.074
Blk	B lymphoid kinase	0.073	Mouse
Gda	guanine deaminase	0.073
B4galnt2	beta-1,4-N-acetyl-galactosaminyl transferase 2	0.073
Src	Rous sarcoma oncogene	0.073	Mouse
Trim34a	tripartite motif-containing 34A	0.072	Mouse
Cblb	Casitas B-lineage lymphoma b	0.070
1810019J16Rik	RIKEN cDNA 1810019J16 gene	0.069
Was	Wiskott-Aldrich syndrome homolog (human)	0.069
Gm885	predicted gene 885	0.068
Tcirg1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3	0.068
Tmem106a	transmembrane protein 106A	0.067
Klra5	killer cell lectin-like receptor, subfamily A, member 5	0.067	Mouse
Ly9	lymphocyte antigen 9	0.067
Ms4a1	membrane-spanning 4-domains, subfamily A, member 1	0.067
Cd7	CD7 antigen	0.066
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.066
Tbk1	TANK-binding kinase 1	0.066
Vmn1r65	vomeronasal 1 receptor 65	0.066
Slc15a3	solute carrier family 15, member 3	0.065
Cga	glycoprotein hormones, alpha subunit	0.065
Ciita	class II transactivator	0.065
Naip1	NLR family, apoptosis inhibitory protein 1	0.064
Tcra	T-cell receptor alpha chain	0.064
Lcp2	lymphocyte cytosolic protein 2	0.064
Bglap	bone gamma carboxyglutamate protein	0.064
Fcrla	Fc receptor-like A	0.063
Iigp1	interferon inducible GTPase 1	0.063
Sfn	stratifin	0.063
Fpr1	formyl peptide receptor 1	0.062
Ripk2	receptor (TNFRSF)-interacting serine-threonine kinase 2	0.062
Plekho2	pleckstrin homology domain containing, family O member 2	0.062
Serpinb9	serine (or cysteine) peptidase inhibitor, clade B, member 9	0.062
Cd38	CD38 antigen	0.061
Il1b	interleukin 1 beta	0.060
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.060
Tlr6	toll-like receptor 6	0.060	Mouse
Mpeg1	macrophage expressed gene 1	0.060
5430427O19Rik	RIKEN cDNA 5430427O19 gene	0.059
Ptk6	PTK6 protein tyrosine kinase 6	0.059	Mouse
Socs3	suppressor of cytokine signaling 3	0.059
Plek	pleckstrin	0.057
Mmp8	matrix metallopeptidase 8	0.056
Igk	immunoglobulin kappa chain complex	0.056
Pla2g2e	phospholipase A2, group IIE	0.056
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.056
Rnase6	ribonuclease, RNase A family, 6	0.056
Cd300ld	CD300 molecule-like family member d	0.056	Mouse
Gm6377	predicted gene 6377	0.055
Cd14	CD14 antigen	0.055
Ikbkb	inhibitor of kappaB kinase beta	0.054
Clec7a	C-type lectin domain family 7, member a	0.054
Il2ra	interleukin 2 receptor, alpha chain	0.054
Trim12c	tripartite motif-containing 12C	0.054	Human Mouse
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.054
Itk	IL2-inducible T-cell kinase	0.053
Gbp6	guanylate binding protein 6	0.053
Parp10	poly (ADP-ribose) polymerase family, member 10	0.052
Sp110	Sp110 nuclear body protein	0.052
Ifnar2	interferon (alpha and beta) receptor 2	0.052
Ceacam11	carcinoembryonic antigen-related cell adhesion molecule 11	0.051
Ly75	lymphocyte antigen 75	0.051
AF251705	cDNA sequence AF251705	0.050	Mouse
Bst1	bone marrow stromal cell antigen 1	0.050
Hgf	hepatocyte growth factor	0.050
Ifit3	interferon-induced protein with tetratricopeptide repeats 3	0.049
Gpr84	G protein-coupled receptor 84	0.049
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.049
Cxcr3	chemokine (C-X-C motif) receptor 3	0.049
Rnf135	ring finger protein 135	0.049
Treml4	triggering receptor expressed on myeloid cells-like 4	0.049
Laptm5	lysosomal-associated protein transmembrane 5	0.048
Clec5a	C-type lectin domain family 5, member a	0.048
Nlrc5	NLR family, CARD domain containing 5	0.048
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.048
Ctsc	cathepsin C	0.048
Hspa9	heat shock protein 9	0.047
Adam15	a disintegrin and metallopeptidase domain 15 (metargidin)	0.047	Mouse
Card11	caspase recruitment domain family, member 11	0.046
Trim12a	tripartite motif-containing 12A	0.046	Human Mouse
Stat3	signal transducer and activator of transcription 3	0.046
Fcgr1	Fc receptor, IgG, high affinity I	0.046
Cysltr1	cysteinyl leukotriene receptor 1	0.046	Mouse
Rgs1	regulator of G-protein signaling 1	0.046
Pla2g2d	phospholipase A2, group IID	0.045
Il10ra	interleukin 10 receptor, alpha	0.045
Rhog	ras homolog gene family, member G	0.045
5430435G22Rik	RIKEN cDNA 5430435G22 gene	0.045
Ly6i	lymphocyte antigen 6 complex, locus I	0.044
Apobr	apolipoprotein B receptor	0.044
Dnm1	dynamin 1	0.044
Gm12185	predicted gene 12185	0.044
Adam17	a disintegrin and metallopeptidase domain 17	0.044	Mouse
Clec2i	C-type lectin domain family 2, member i	0.043
Plekhn1	pleckstrin homology domain containing, family N member 1	0.043
AB124611	cDNA sequence AB124611	0.043
Cytip	cytohesin 1 interacting protein	0.043
Adap2	ArfGAP with dual PH domains 2	0.043
Star	steroidogenic acute regulatory protein	0.043
Il17ra	interleukin 17 receptor A	0.043
C3ar1	complement component 3a receptor 1	0.042
Rdh1	retinol dehydrogenase 1 (all trans)	0.042
Gpr18	G protein-coupled receptor 18	0.042
Pion	pigeon homolog (Drosophila)	0.042
Itsn1	intersectin 1 (SH3 domain protein 1A)	0.042
Slamf6	SLAM family member 6	0.042
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.042
Timp1	tissue inhibitor of metalloproteinase 1	0.042
Cxcl13	chemokine (C-X-C motif) ligand 13	0.041
Tlr5	toll-like receptor 5	0.041	Human Mouse
Gbp1	guanylate binding protein 1	0.041
Lyzl1	lysozyme-like 1	0.041
Fpr2	formyl peptide receptor 2	0.041
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.041
Tgfb2	transforming growth factor, beta 2	0.040
Ube2l6	ubiquitin-conjugating enzyme E2L 6	0.040
Cxcr4	chemokine (C-X-C motif) receptor 4	0.040
Stat4	signal transducer and activator of transcription 4	0.040
Nmur2	neuromedin U receptor 2	0.040
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.040	Mouse
Lat2	linker for activation of T cells family, member 2	0.040
Tgtp2	T-cell specific GTPase 2	0.040
Map2k3	mitogen-activated protein kinase kinase 3	0.039	Worm
Jak2	Janus kinase 2	0.039
Camk2b	calcium/calmodulin-dependent protein kinase II, beta	0.039
Tirap	toll-interleukin 1 receptor (TIR) domain-containing adaptor protein	0.039
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.039	Mouse
Ccl2	chemokine (C-C motif) ligand 2	0.039
Dusp2	dual specificity phosphatase 2	0.039
Ccr5	chemokine (C-C motif) receptor 5	0.039
Chuk	conserved helix-loop-helix ubiquitous kinase	0.039
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.039	Zebrafish
Klrb1f	killer cell lectin-like receptor subfamily B member 1F	0.039
St6galnac1	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1	0.039
Shisa5	shisa homolog 5 (Xenopus laevis)	0.038
Cd209a	CD209a antigen	0.038
Btla	B and T lymphocyte associated	0.038
Slc12a6	solute carrier family 12, member 6	0.038
Mlkl	mixed lineage kinase domain-like	0.037
St3gal1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	0.037
Samd9l	sterile alpha motif domain containing 9-like	0.037
Zc3h12a	zinc finger CCCH type containing 12A	0.037
Ebi3	Epstein-Barr virus induced gene 3	0.037
Mib1	mindbomb homolog 1 (Drosophila)	0.037
Il1a	interleukin 1 alpha	0.037
Mertk	c-mer proto-oncogene tyrosine kinase	0.037	Mouse
Slc5a4a	solute carrier family 5, member 4a	0.037
Ifitm3	interferon induced transmembrane protein 3	0.036
Hpgds	hematopoietic prostaglandin D synthase	0.036
1810030J14Rik	RIKEN cDNA 1810030J14 gene	0.036
Tifab	TRAF-interacting protein with forkhead-associated domain, family member B	0.036
Gm7609	predicted pseudogene 7609	0.036
Fam26f	family with sequence similarity 26, member F	0.036
Atp8b4	ATPase, class I, type 8B, member 4	0.036
Klra17	killer cell lectin-like receptor, subfamily A, member 17	0.036	Mouse
Zc3hav1	zinc finger CCCH type, antiviral 1	0.036	Human
Evi2a	ecotropic viral integration site 2a	0.036
Mvp	major vault protein	0.036
Vdr	vitamin D receptor	0.036
Xcr1	chemokine (C motif) receptor 1	0.036
Oas1b	2'-5' oligoadenylate synthetase 1B	0.036
Sh3bp2	SH3-domain binding protein 2	0.036
Il4	interleukin 4	0.036
Mnda	myeloid cell nuclear differentiation antigen	0.035
Sharpin	SHANK-associated RH domain interacting protein	0.035
Hck	hemopoietic cell kinase	0.035	Mouse
Cnr2	cannabinoid receptor 2 (macrophage)	0.035
Rasa4	RAS p21 protein activator 4	0.035
Clec4b1	C-type lectin domain family 4, member b1	0.035
Samsn1	SAM domain, SH3 domain and nuclear localization signals, 1	0.035
Reg3d	regenerating islet-derived 3 delta	0.035	Mouse
Opn4	opsin 4 (melanopsin)	0.035
Mmp9	matrix metallopeptidase 9	0.035
Mrpl3	mitochondrial ribosomal protein L3	0.035
Klrc1	killer cell lectin-like receptor subfamily C, member 1	0.035	Mouse
C5ar1	complement component 5a receptor 1	0.035
Sirpa	signal-regulatory protein alpha	0.034
Zc3h12d	zinc finger CCCH type containing 12D	0.034
Sirpb1a	signal-regulatory protein beta 1A	0.034
Sell	selectin, lymphocyte	0.034
Art2a-ps	ADP-ribosyltransferase 2a, pseudogene	0.034
Clca3	chloride channel calcium activated 3	0.034
Nhej1	nonhomologous end-joining factor 1	0.034
Bex6	brain expressed gene 6	0.034
Cd83	CD83 antigen	0.034
Trafd1	TRAF type zinc finger domain containing 1	0.034
Klrb1c	killer cell lectin-like receptor subfamily B member 1C	0.034
Foxp3	forkhead box P3	0.033
Cd160	CD160 antigen	0.033
Rnase1	ribonuclease, RNase A family, 1 (pancreatic)	0.033
Rgs18	regulator of G-protein signaling 18	0.033
Cd244	CD244 natural killer cell receptor 2B4	0.033
Cml3	camello-like 3	0.033
Hsh2d	hematopoietic SH2 domain containing	0.033
Kmo	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.033
Gbgt1	globoside alpha-1,3-N-acetylgalactosaminyltransferase 1	0.033
C130050O18Rik	RIKEN cDNA C130050O18 gene	0.032
Chl1	cell adhesion molecule with homology to L1CAM	0.032
Prkcc	protein kinase C, gamma	0.032
Vav2	vav 2 oncogene	0.032
Plbd1	phospholipase B domain containing 1	0.032
A630033H20Rik	RIKEN cDNA A630033H20 gene	0.032
Ptk2	PTK2 protein tyrosine kinase 2	0.032
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.032
Jup	junction plakoglobin	0.032
Ccr1	chemokine (C-C motif) receptor 1	0.032
Cxcl2	chemokine (C-X-C motif) ligand 2	0.032
Dmtf1	cyclin D binding myb-like transcription factor 1	0.032
Trpm2	transient receptor potential cation channel, subfamily M, member 2	0.032
Il1r2	interleukin 1 receptor, type II	0.032
Klrb1a	killer cell lectin-like receptor subfamily B member 1A	0.032
Tnfrsf23	tumor necrosis factor receptor superfamily, member 23	0.032
Rag1	recombination activating gene 1	0.032
Dclre1c	DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)	0.032
Mmp12	matrix metallopeptidase 12	0.032
Itgae	integrin alpha E, epithelial-associated	0.031
Cdh1	cadherin 1	0.031
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.031
Zg16	zymogen granule protein 16	0.031
Ms4a8a	membrane-spanning 4-domains, subfamily A, member 8A	0.031
Msgn1	mesogenin 1	0.031
Irf4	interferon regulatory factor 4	0.031
Apobec3	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3	0.031
Pml	promyelocytic leukemia	0.031
Pld4	phospholipase D family, member 4	0.031
Clnk	cytokine-dependent hematopoietic cell linker	0.031
Inhba	inhibin beta-A	0.031
Fyb	FYN binding protein	0.031
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.031
Atp1a3	ATPase, Na+/K+ transporting, alpha 3 polypeptide	0.030
Pxn	paxillin	0.030
Ifit2	interferon-induced protein with tetratricopeptide repeats 2	0.030
Plaur	plasminogen activator, urokinase receptor	0.030
Runx3	runt related transcription factor 3	0.030
Phc2	polyhomeotic-like 2 (Drosophila)	0.030
Diap1	diaphanous homolog 1 (Drosophila)	0.030
Lrrc18	leucine rich repeat containing 18	0.030
Siglecg	sialic acid binding Ig-like lectin G	0.030
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.030
Cd209d	CD209d antigen	0.029
Igf1	insulin-like growth factor 1	0.029
Serpinb7	serine (or cysteine) peptidase inhibitor, clade B, member 7	0.029
Sla	src-like adaptor	0.029
1810033B17Rik	RIKEN cDNA 1810033B17 gene	0.029
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.029
Tgfb1	transforming growth factor, beta 1	0.029
Hbb-y	hemoglobin Y, beta-like embryonic chain	0.029
Havcr2	hepatitis A virus cellular receptor 2	0.029
Defa-rs1	defensin, alpha, related sequence 1	0.029
Mthfs	5, 10-methenyltetrahydrofolate synthetase	0.029
Clec4a3	C-type lectin domain family 4, member a3	0.029
Foxn1	forkhead box N1	0.028
Slamf1	signaling lymphocytic activation molecule family member 1	0.028
Rasgrf2	RAS protein-specific guanine nucleotide-releasing factor 2	0.028
Ccl5	chemokine (C-C motif) ligand 5	0.028
Vwa5a	von Willebrand factor A domain containing 5A	0.028
Il1rl2	interleukin 1 receptor-like 2	0.028
Tnfsf13b	tumor necrosis factor (ligand) superfamily, member 13b	0.028
Ms4a4b	membrane-spanning 4-domains, subfamily A, member 4B	0.028
Il4ra	interleukin 4 receptor, alpha	0.028
Sbno2	strawberry notch homolog 2 (Drosophila)	0.028
Foxf2	forkhead box F2	0.027
Pbsn	probasin	0.027
Cd200r1	CD200 receptor 1	0.027
Adam8	a disintegrin and metallopeptidase domain 8	0.027
Prss30	protease, serine, 30	0.027
Tcfec	transcription factor EC	0.027
Gpr65	G-protein coupled receptor 65	0.027
Nlrp3	NLR family, pyrin domain containing 3	0.027	Mouse
Tnfrsf13c	tumor necrosis factor receptor superfamily, member 13c	0.027
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.027
Timm10	translocase of inner mitochondrial membrane 10 homolog (yeast)	0.027
Tnfsf8	tumor necrosis factor (ligand) superfamily, member 8	0.027
Adamdec1	ADAM-like, decysin 1	0.027	Mouse
Socs1	suppressor of cytokine signaling 1	0.026
Homer1	homer homolog 1 (Drosophila)	0.026
S100a9	S100 calcium binding protein A9 (calgranulin B)	0.026
Thrb	thyroid hormone receptor beta	0.026
Nfatc1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.026
Niacr1	niacin receptor 1	0.026
Plekha5	pleckstrin homology domain containing, family A member 5	0.026
Atad3a	ATPase family, AAA domain containing 3A	0.026
Syngr2	synaptogyrin 2	0.026
Ly96	lymphocyte antigen 96	0.026	Human
Prf1	perforin 1 (pore forming protein)	0.026
Oas1a	2'-5' oligoadenylate synthetase 1A	0.026
Hcls1	hematopoietic cell specific Lyn substrate 1	0.026
Galntl5	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5	0.026
Cr2	complement receptor 2	0.026
Gvin1	GTPase, very large interferon inducible 1	0.025
Ms4a6c	membrane-spanning 4-domains, subfamily A, member 6C	0.025
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.025
Ptger2	prostaglandin E receptor 2 (subtype EP2)	0.025
Ccr4	chemokine (C-C motif) receptor 4	0.025
Cpb1	carboxypeptidase B1 (tissue)	0.025
Cxcl16	chemokine (C-X-C motif) ligand 16	0.025
Cd177	CD177 antigen	0.025
Tlr9	toll-like receptor 9	0.025	Mouse
B430306N03Rik	RIKEN cDNA B430306N03 gene	0.025	Mouse
Tnfrsf14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.025
H2-Eb2	histocompatibility 2, class II antigen E beta2	0.025
Pkhd1l1	polycystic kidney and hepatic disease 1-like 1	0.025
Cela3b	chymotrypsin-like elastase family, member 3B	0.025
Nkg7	natural killer cell group 7 sequence	0.025
Il1r1	interleukin 1 receptor, type I	0.025
Nfkbid	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta	0.025
Efhd2	EF hand domain containing 2	0.025
Cd5l	CD5 antigen-like	0.024
Il15	interleukin 15	0.024
Fam111a	family with sequence similarity 111, member A	0.024
Neurl3	neuralized homolog 3 homolog (Drosophila)	0.024
Fes	feline sarcoma oncogene	0.024
Ms4a10	membrane-spanning 4-domains, subfamily A, member 10	0.024
Cd274	CD274 antigen	0.024	Mouse
Fcgr3	Fc receptor, IgG, low affinity III	0.024
Ms4a6d	membrane-spanning 4-domains, subfamily A, member 6D	0.024
Etv6	ets variant gene 6 (TEL oncogene)	0.024
Xaf1	XIAP associated factor 1	0.024
6330590E21Rik	RIKEN cDNA 6330590E21 gene	0.024
Cd72	CD72 antigen	0.024
Aim1	absent in melanoma 1	0.024
Tyk2	tyrosine kinase 2	0.024
Klf3	Kruppel-like factor 3 (basic)	0.024
Slc6a2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.024
Gpr33	G protein-coupled receptor 33	0.024
Gdf9	growth differentiation factor 9	0.024
Slc6a14	solute carrier family 6 (neurotransmitter transporter), member 14	0.024
Camp	cathelicidin antimicrobial peptide	0.024
Fpr3	formyl peptide receptor 3	0.024
Dab1	disabled homolog 1 (Drosophila)	0.024
Fut7	fucosyltransferase 7	0.024
Smok3a	sperm motility kinase 3A	0.024
Irg1	immunoresponsive gene 1	0.023
Tbx21	T-box 21	0.023
Dok1	docking protein 1	0.023
2210407C18Rik	RIKEN cDNA 2210407C18 gene	0.023
Gpr35	G protein-coupled receptor 35	0.023
March1	membrane-associated ring finger (C3HC4) 1	0.023
Bhlha15	basic helix-loop-helix family, member a15	0.023
Faim3	Fas apoptotic inhibitory molecule 3	0.023
Xcl1	chemokine (C motif) ligand 1	0.023
Scgb3a1	secretoglobin, family 3A, member 1	0.023
Ifi35	interferon-induced protein 35	0.023
Pld1	phospholipase D1	0.023
Cdcp1	CUB domain containing protein 1	0.023
Atr	ataxia telangiectasia and Rad3 related	0.023
Traf1	TNF receptor-associated factor 1	0.023	Mouse
Snx20	sorting nexin 20	0.022
Lilrb3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.022
Gp2	glycoprotein 2 (zymogen granule membrane)	0.022
Itgam	integrin alpha M	0.022
Ikbke	inhibitor of kappaB kinase epsilon	0.022
P2ry2	purinergic receptor P2Y, G-protein coupled 2	0.022	Mouse
Ccbp2	chemokine binding protein 2	0.022
AW112010	expressed sequence AW112010	0.022
Dlg3	discs, large homolog 3 (Drosophila)	0.022
Cyp26c1	cytochrome P450, family 26, subfamily c, polypeptide 1	0.022
H2-Ob	histocompatibility 2, O region beta locus	0.022
Vmn1r45	vomeronasal 1 receptor 45	0.022
Pvrl2	poliovirus receptor-related 2	0.022
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.022
Cmtm6	CKLF-like MARVEL transmembrane domain containing 6	0.022
Adora2b	adenosine A2b receptor	0.022
P2ry6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.022
Gbp10	guanylate-binding protein 10	0.021
Cd4	CD4 antigen	0.021
Pik3r5	phosphoinositide-3-kinase, regulatory subunit 5, p101	0.021
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.021
Ncf4	neutrophil cytosolic factor 4	0.021
Reg1	regenerating islet-derived 1	0.021	Mouse
Cplx4	complexin 4	0.021
Csf1r	colony stimulating factor 1 receptor	0.021
AI607873	expressed sequence AI607873	0.021
Il20	interleukin 20	0.021
Cdh17	cadherin 17	0.021
Ccrl2	chemokine (C-C motif) receptor-like 2	0.021
Galnt3	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3	0.021
1810011H11Rik	RIKEN cDNA 1810011H11 gene	0.021
Traf5	TNF receptor-associated factor 5	0.021
Cry1	cryptochrome 1 (photolyase-like)	0.021
Grm1	glutamate receptor, metabotropic 1	0.021
Mmp15	matrix metallopeptidase 15	0.021
Tnfrsf11b	tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)	0.021
Cd209e	CD209e antigen	0.021
Cd300a	CD300A antigen	0.021	Mouse
Mx2	myxovirus (influenza virus) resistance 2	0.021
Tmc6	transmembrane channel-like gene family 6	0.021
Napsa	napsin A aspartic peptidase	0.021
Pydc4	pyrin domain containing 4	0.020
Tmem173	transmembrane protein 173	0.020
Prss32	protease, serine, 32	0.020
Klre1	killer cell lectin-like receptor family E member 1	0.020
Ptgs1	prostaglandin-endoperoxide synthase 1	0.020
Dhx58	DEXH (Asp-Glu-X-His) box polypeptide 58	0.020
Trim26	tripartite motif-containing 26	0.020	Mouse
Sos1	son of sevenless homolog 1 (Drosophila)	0.020
Nuak2	NUAK family, SNF1-like kinase, 2	0.020
Osbpl11	oxysterol binding protein-like 11	0.020
Znfx1	zinc finger, NFX1-type containing 1	0.020
Selp	selectin, platelet	0.020
A630001G21Rik	RIKEN cDNA A630001G21 gene	0.020
Klra7	killer cell lectin-like receptor, subfamily A, member 7	0.020	Mouse
Has2	hyaluronan synthase 2	0.020
Tff3	trefoil factor 3, intestinal	0.020
Mrgpra1	MAS-related GPR, member A1	0.020
Entpd7	ectonucleoside triphosphate diphosphohydrolase 7	0.020
Spon2	spondin 2, extracellular matrix protein	0.020
Stap1	signal transducing adaptor family member 1	0.020
Cngb3	cyclic nucleotide gated channel beta 3	0.020
Ccl22	chemokine (C-C motif) ligand 22	0.020
Dapp1	dual adaptor for phosphotyrosine and 3-phosphoinositides 1	0.020
Rc3h1	RING CCCH (C3H) domains 1	0.020
Ms4a6b	membrane-spanning 4-domains, subfamily A, member 6B	0.020
Slamf9	SLAM family member 9	0.020
Tas1r3	taste receptor, type 1, member 3	0.020
Slc25a45	solute carrier family 25, member 45	0.020
Pdc	phosducin	0.019
Angptl1	angiopoietin-like 1	0.019
Ccl24	chemokine (C-C motif) ligand 24	0.019
Trim5	tripartite motif-containing 5	0.019	Human Mouse
Ptafr	platelet-activating factor receptor	0.019
Lpcat2	lysophosphatidylcholine acyltransferase 2	0.019
LOC677008	natural killer cell receptor 2B4-like	0.019
Elf1	E74-like factor 1	0.019
H2-Q6	histocompatibility 2, Q region locus 6	0.019
Etv3	ets variant gene 3	0.019
Bmx	BMX non-receptor tyrosine kinase	0.019
Trim14	tripartite motif-containing 14	0.019
Gpa33	glycoprotein A33 (transmembrane)	0.019
Evi2b	ecotropic viral integration site 2b	0.019
Mafb	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.019
Irak2	interleukin-1 receptor-associated kinase 2	0.019	Mouse
Cd1d2	CD1d2 antigen	0.019
Pcdhb1	protocadherin beta 1	0.019
Clec4a2	C-type lectin domain family 4, member a2	0.019
Slurp1	secreted Ly6/Plaur domain containing 1	0.019
Igj	immunoglobulin joining chain	0.019
Cpne3	copine III	0.019
Il5ra	interleukin 5 receptor, alpha	0.019
Slc12a4	solute carrier family 12, member 4	0.019
Nmi	N-myc (and STAT) interactor	0.019
Reg3b	regenerating islet-derived 3 beta	0.019	Mouse
Grin2a	glutamate receptor, ionotropic, NMDA2A (epsilon 1)	0.019
Cxcr5	chemokine (C-X-C motif) receptor 5	0.018
Slfn5	schlafen 5	0.018
Rhbdf2	rhomboid 5 homolog 2 (Drosophila)	0.018
Prss16	protease, serine, 16 (thymus)	0.018
Kcna6	potassium voltage-gated channel, shaker-related, subfamily, member 6	0.018
Prpmp5	proline-rich protein MP5	0.018
Ms4a7	membrane-spanning 4-domains, subfamily A, member 7	0.018
Cacna1f	calcium channel, voltage-dependent, alpha 1F subunit	0.018
Ggta1	glycoprotein galactosyltransferase alpha 1, 3	0.018
Isg20	interferon-stimulated protein	0.018
Adar	adenosine deaminase, RNA-specific	0.018
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.018
Parvg	parvin, gamma	0.018
Vpreb3	pre-B lymphocyte gene 3	0.018
Mpo	myeloperoxidase	0.018
Klra21	killer cell lectin-like receptor subfamily A, member 21	0.018
Slc7a11	solute carrier family 7 (cationic amino acid transporter, y+ system), member 11	0.018
Sh2d1b1	SH2 domain protein 1B1	0.018
Serpini2	serine (or cysteine) peptidase inhibitor, clade I, member 2	0.018
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.018
Erap1	endoplasmic reticulum aminopeptidase 1	0.018
Vps37c	vacuolar protein sorting 37C (yeast)	0.018
9030625A04Rik	RIKEN cDNA 9030625A04 gene	0.018
Fgd3	FYVE, RhoGEF and PH domain containing 3	0.018
Mndal	myeloid nuclear differentiation antigen like	0.018
Pira2	paired-Ig-like receptor A2	0.018
Zcchc6	zinc finger, CCHC domain containing 6	0.017
Ccr1l1	chemokine (C-C motif) receptor 1-like 1	0.017
2310014H01Rik	RIKEN cDNA 2310014H01 gene	0.017
Usp9y	ubiquitin specific peptidase 9, Y chromosome	0.017
Adad1	adenosine deaminase domain containing 1 (testis specific)	0.017
Trim30b	tripartite motif-containing 30B	0.017
St8sia4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.017
Irf8	interferon regulatory factor 8	0.017	Mouse
Prss2	protease, serine, 2	0.017
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.017
Pcdhb5	protocadherin beta 5	0.017
Parp12	poly (ADP-ribose) polymerase family, member 12	0.017
Stxbp3a	syntaxin binding protein 3A	0.017
Svs4	seminal vesicle secretory protein 4	0.017
Tpcn2	two pore segment channel 2	0.017
Hspa1b	heat shock protein 1B	0.017
Muc3	mucin 3, intestinal	0.017
Il21r	interleukin 21 receptor	0.017
Plac8	placenta-specific 8	0.017
Ltb	lymphotoxin B	0.017
Fabp4	fatty acid binding protein 4, adipocyte	0.017
Icosl	icos ligand	0.017	Mouse
Slc25a2	solute carrier family 25 (mitochondrial carrier, ornithine transporter) member 2	0.017
Serpina3g	serine (or cysteine) peptidase inhibitor, clade A, member 3G	0.017