IMP: Integrative Multi-species Prediction

Mus musculus

224 genes annotated in mouse

positive regulation of cell death

Any process that increases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of cell death"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "positive regulation of cell death" (in gray)

Name	Description	Probability	Func Analog Organism
Tnf	tumor necrosis factor	0.999
Pten	phosphatase and tensin homolog	0.998
Ctnnb1	catenin (cadherin associated protein), beta 1	0.995	Human
Rarg	retinoic acid receptor, gamma	0.989
Rxra	retinoid X receptor alpha	0.988	Rat
Bcl2	B-cell leukemia/lymphoma 2	0.985	Mouse
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.984
Gli3	GLI-Kruppel family member GLI3	0.983	Worm
Otx2	orthodenticle homolog 2 (Drosophila)	0.983
Gli2	GLI-Kruppel family member GLI2	0.982	Worm
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.981
Igh	immunoglobulin heavy chain complex	0.979
Apc	adenomatosis polyposis coli	0.977
Fgfr2	fibroblast growth factor receptor 2	0.972	Mouse
Ptgs2	prostaglandin-endoperoxide synthase 2	0.965	Rat
Trp53	transformation related protein 53	0.965
Nos3	nitric oxide synthase 3, endothelial cell	0.947	Rat
Ren1	renin 1 structural	0.943
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.940	Mouse
Lyz2	lysozyme 2	0.938
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.935	Human
Tgfb1	transforming growth factor, beta 1	0.934	Mouse Rat
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.926
Mcl1	myeloid cell leukemia sequence 1	0.923
Mapk14	mitogen-activated protein kinase 14	0.918	Mouse
Pax2	paired box gene 2	0.915
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.915
Ptch1	patched homolog 1	0.908
Fas	Fas (TNF receptor superfamily member 6)	0.907
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.905
Vegfa	vascular endothelial growth factor A	0.899
En1	engrailed 1	0.896
Fgfr1	fibroblast growth factor receptor 1	0.887	Mouse
Skil	SKI-like	0.883
Cd44	CD44 antigen	0.882
Nos2	nitric oxide synthase 2, inducible	0.880	Rat
Foxc1	forkhead box C1	0.858
Shh	sonic hedgehog	0.858
Csf1	colony stimulating factor 1 (macrophage)	0.847
Mmp9	matrix metallopeptidase 9	0.839
Axin1	axin 1	0.829
Ikbkg	inhibitor of kappaB kinase gamma	0.829
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.828	Mouse Fly
Nf1	neurofibromatosis 1	0.810
Tgfb2	transforming growth factor, beta 2	0.806
Klf6	Kruppel-like factor 6	0.805
Sfrp2	secreted frizzled-related protein 2	0.805	Human Mouse
Foxc2	forkhead box C2	0.803
Socs1	suppressor of cytokine signaling 1	0.791
Msx2	homeobox, msh-like 2	0.789
Acvr1	activin A receptor, type 1	0.776	Mouse
Ret	ret proto-oncogene	0.776	Human
Zeb1	zinc finger E-box binding homeobox 1	0.761
Ncoa3	nuclear receptor coactivator 3	0.757	Mouse
Cd19	CD19 antigen	0.753
Zfp36	zinc finger protein 36	0.752
Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	0.745
Casp8	caspase 8	0.744
Spnb2	spectrin beta 2	0.740
Id1	inhibitor of DNA binding 1	0.739
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.739
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.737
Fos	FBJ osteosarcoma oncogene	0.736
Egr1	early growth response 1	0.734	Rat
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.726	Rat
Jun	Jun oncogene	0.715	Rat
Smad3	MAD homolog 3 (Drosophila)	0.702	Human Rat
Gdnf	glial cell line derived neurotrophic factor	0.697
Rara	retinoic acid receptor, alpha	0.694	Mouse
Ntf3	neurotrophin 3	0.693
Notch1	Notch gene homolog 1 (Drosophila)	0.686
Bax	BCL2-associated X protein	0.685
Cd40	CD40 antigen	0.680	Human
Socs3	suppressor of cytokine signaling 3	0.678
Rarb	retinoic acid receptor, beta	0.671
Sin3a	transcriptional regulator, SIN3A (yeast)	0.670
Braf	Braf transforming gene	0.664
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.664	Human Mouse
Bmp7	bone morphogenetic protein 7	0.663
Sox9	SRY-box containing gene 9	0.663
Bmp4	bone morphogenetic protein 4	0.662	Human Rat
Anxa3	annexin A3	0.657	Mouse
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.642
Lef1	lymphoid enhancer binding factor 1	0.638	Mouse
Gja1	gap junction protein, alpha 1	0.636
Tcf4	transcription factor 4	0.634	Worm
Thbs1	thrombospondin 1	0.629	Human
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.623
Dok1	docking protein 1	0.615
Il6st	interleukin 6 signal transducer	0.608
Wt1	Wilms tumor 1 homolog	0.607	Human
Bcl6	B-cell leukemia/lymphoma 6	0.603	Human
Fst	follistatin	0.601
Runx2	runt related transcription factor 2	0.597	Mouse Fly
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.592
Atm	ataxia telangiectasia mutated homolog (human)	0.590
Cycs	cytochrome c, somatic	0.586
Dusp1	dual specificity phosphatase 1	0.586
Prrx1	paired related homeobox 1	0.584
Mdm4	transformed mouse 3T3 cell double minute 4	0.582
Stk4	serine/threonine kinase 4	0.579
Gata5	GATA binding protein 5	0.567
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.564
Cd47	CD47 antigen (Rh-related antigen, integrin-associated signal transducer)	0.564
Adrb3	adrenergic receptor, beta 3	0.561
Rock2	Rho-associated coiled-coil containing protein kinase 2	0.559
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.558	Mouse
Ccr1	chemokine (C-C motif) receptor 1	0.556
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.552
Anxa5	annexin A5	0.548	Mouse
Sh3gl2	SH3-domain GRB2-like 2	0.546	Mouse Worm
Tgfbr2	transforming growth factor, beta receptor II	0.545	Mouse
Cbfa2t3	core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)	0.544
Dlx5	distal-less homeobox 5	0.543
Pfn1	profilin 1	0.537
Gal	galanin	0.535	Rat
Trp73	transformation related protein 73	0.531
Lep	leptin	0.531
Prrx2	paired related homeobox 2	0.529
Gata4	GATA binding protein 4	0.525
Prkce	protein kinase C, epsilon	0.524
Lrrk2	leucine-rich repeat kinase 2	0.518	Human
Dffb	DNA fragmentation factor, beta subunit	0.518
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.513	Mouse
Klf4	Kruppel-like factor 4 (gut)	0.512
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.508
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.508
Id2	inhibitor of DNA binding 2	0.506
Hoxa5	homeobox A5	0.505	Human
Ep300	E1A binding protein p300	0.499
Cyr61	cysteine rich protein 61	0.498
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.497
Gdf5	growth differentiation factor 5	0.491	Mouse
Smo	smoothened homolog (Drosophila)	0.491
Mapk8	mitogen-activated protein kinase 8	0.490
Hoxd13	homeobox D13	0.488	Mouse
Mef2a	myocyte enhancer factor 2A	0.480	Mouse
Sox11	SRY-box containing gene 11	0.477
Msh2	mutS homolog 2 (E. coli)	0.476
Wdr26	WD repeat domain 26	0.475
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.471	Mouse Rat
Hsp90b1	heat shock protein 90, beta (Grp94), member 1	0.470
Tgfbr1	transforming growth factor, beta receptor I	0.470	Human Mouse
Cd7	CD7 antigen	0.470
Alx4	aristaless-like homeobox 4	0.469
S100a9	S100 calcium binding protein A9 (calgranulin B)	0.467	Human
Rb1	retinoblastoma 1	0.464
Ar	androgen receptor	0.462
Meox2	mesenchyme homeobox 2	0.461
Il10	interleukin 10	0.455	Mouse
Adam17	a disintegrin and metallopeptidase domain 17	0.452	Mouse
Ephb3	Eph receptor B3	0.449	Mouse
Adam9	a disintegrin and metallopeptidase domain 9 (meltrin gamma)	0.444	Mouse
Esr2	estrogen receptor 2 (beta)	0.444	Rat
S100a8	S100 calcium binding protein A8 (calgranulin A)	0.442	Human
Plau	plasminogen activator, urokinase	0.442
Fgf5	fibroblast growth factor 5	0.442
Mef2d	myocyte enhancer factor 2D	0.442	Mouse
Cxcl13	chemokine (C-X-C motif) ligand 13	0.439
Notch2	Notch gene homolog 2 (Drosophila)	0.437
Plxnd1	plexin D1	0.437
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.436
Slc40a1	solute carrier family 40 (iron-regulated transporter), member 1	0.429
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.424	Mouse
Hif1a	hypoxia inducible factor 1, alpha subunit	0.422	Rat
Pkd1	polycystic kidney disease 1 homolog	0.419
Wnt2b	wingless related MMTV integration site 2b	0.418	Mouse
Ryr1	ryanodine receptor 1, skeletal muscle	0.417	Worm
Fosb	FBJ osteosarcoma oncogene B	0.417
Insm1	insulinoma-associated 1	0.416
Huwe1	HECT, UBA and WWE domain containing 1	0.415
Adam10	a disintegrin and metallopeptidase domain 10	0.413
Ctsw	cathepsin W	0.411
Blnk	B-cell linker	0.409
Il1r1	interleukin 1 receptor, type I	0.408
Pax3	paired box gene 3	0.407
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.407	Rat
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.404
Fgf8	fibroblast growth factor 8	0.401
Dbp	D site albumin promoter binding protein	0.401	Worm
Sfrp1	secreted frizzled-related protein 1	0.399
S100a10	S100 calcium binding protein A10 (calpactin)	0.398
Ch25h	cholesterol 25-hydroxylase	0.397
Sox3	SRY-box containing gene 3	0.397
Irf1	interferon regulatory factor 1	0.394
Hoxc6	homeobox C6	0.392
Sh2d2a	SH2 domain protein 2A	0.390
Ccnd1	cyclin D1	0.387
Il2rb	interleukin 2 receptor, beta chain	0.386
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.384
Plat	plasminogen activator, tissue	0.383
Drd2	dopamine receptor D2	0.382
Cxcr5	chemokine (C-X-C motif) receptor 5	0.379
Rhbdl3	rhomboid, veinlet-like 3 (Drosophila)	0.379
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.378
Atoh1	atonal homolog 1 (Drosophila)	0.377	Mouse
Ltb	lymphotoxin B	0.377
Hic1	hypermethylated in cancer 1	0.377
Rhob	ras homolog gene family, member B	0.372	Human
Myc	myelocytomatosis oncogene	0.371
Notch4	Notch gene homolog 4 (Drosophila)	0.365	Mouse
Cdk4	cyclin-dependent kinase 4	0.364
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.361
Pdcd6ip	programmed cell death 6 interacting protein	0.361
Nodal	nodal	0.359	Mouse
Atf3	activating transcription factor 3	0.358
Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.357
Hoxa13	homeobox A13	0.355
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.355
Apaf1	apoptotic peptidase activating factor 1	0.355
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.354
Mdm2	transformed mouse 3T3 cell double minute 2	0.353
Wnt10b	wingless related MMTV integration site 10b	0.353	Mouse
Meox1	mesenchyme homeobox 1	0.353
Mb	myoglobin	0.352
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.352
Runx1	runt related transcription factor 1	0.352	Mouse Fly
Htra3	HtrA serine peptidase 3	0.352	Mouse Fly
Rac1	RAS-related C3 botulinum substrate 1	0.352
Kit	kit oncogene	0.351
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.349
Gdf11	growth differentiation factor 11	0.346	Mouse
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.346
Anxa1	annexin A1	0.343
Efs	embryonal Fyn-associated substrate	0.342
Pthlh	parathyroid hormone-like peptide	0.339
Smad4	MAD homolog 4 (Drosophila)	0.338
Neurog2	neurogenin 2	0.337	Mouse
Pax9	paired box gene 9	0.336
Chrd	chordin	0.335
Htt	huntingtin	0.334
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.334
Lhx1	LIM homeobox protein 1	0.332
Fasl	Fas ligand (TNF superfamily, member 6)	0.331	Human Mouse Rat
Stub1	STIP1 homology and U-Box containing protein 1	0.330
Tef	thyrotroph embryonic factor	0.330	Worm
Traf3ip2	TRAF3 interacting protein 2	0.328
Mef2c	myocyte enhancer factor 2C	0.326
Ptk2	PTK2 protein tyrosine kinase 2	0.326
Cxcl2	chemokine (C-X-C motif) ligand 2	0.325
Ephb2	Eph receptor B2	0.325	Mouse
Pgr	progesterone receptor	0.325	Mouse
Hoxc5	homeobox C5	0.324
Stat5a	signal transducer and activator of transcription 5A	0.323	Mouse
Foxd2	forkhead box D2	0.322
Agtr1a	angiotensin II receptor, type 1a	0.322
St8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.320
Bcl3	B-cell leukemia/lymphoma 3	0.319
Bcl2l1	BCL2-like 1	0.318
T	brachyury	0.318
Cacybp	calcyclin binding protein	0.318
Trib3	tribbles homolog 3 (Drosophila)	0.318
Foxp3	forkhead box P3	0.316
Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3	0.315
Lck	lymphocyte protein tyrosine kinase	0.313	Human Mouse
Thra	thyroid hormone receptor alpha	0.310	Mouse
Isl1	ISL1 transcription factor, LIM/homeodomain	0.310
Rnf19a	ring finger protein 19A	0.310
Syp	synaptophysin	0.309
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.307
Adam12	a disintegrin and metallopeptidase domain 12 (meltrin alpha)	0.307	Mouse
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.306	Mouse
Ptgir	prostaglandin I receptor (IP)	0.306
Hivep2	human immunodeficiency virus type I enhancer binding protein 2	0.305
E2f1	E2F transcription factor 1	0.305	Fly
Ptch2	patched homolog 2	0.303
Gpr132	G protein-coupled receptor 132	0.302
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.301
Hsp90aa1	heat shock protein 90, alpha (cytosolic), class A member 1	0.300
Nfatc3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	0.300	Mouse
Omp	olfactory marker protein	0.299
Hoxd11	homeobox D11	0.299
Nos1	nitric oxide synthase 1, neuronal	0.298	Rat
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.296
Numb	numb gene homolog (Drosophila)	0.296
Cd9	CD9 antigen	0.296
Ccl22	chemokine (C-C motif) ligand 22	0.294
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.293
Stat3	signal transducer and activator of transcription 3	0.293	Mouse
Dmbx1	diencephalon/mesencephalon homeobox 1	0.293
Slc6a2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.290
Nfatc4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	0.289
Foxf1a	forkhead box F1a	0.289
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.289	Mouse Rat
Ilk	integrin linked kinase	0.287
Pxn	paxillin	0.287
Fzd4	frizzled homolog 4 (Drosophila)	0.287
Aplp2	amyloid beta (A4) precursor-like protein 2	0.286
Hdac7	histone deacetylase 7	0.286
Barx1	BarH-like homeobox 1	0.286
Jag1	jagged 1	0.285
Ddah2	dimethylarginine dimethylaminohydrolase 2	0.284
Ccl2	chemokine (C-C motif) ligand 2	0.282
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.281
Ifngr1	interferon gamma receptor 1	0.281
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.281
Cd22	CD22 antigen	0.279	Mouse
Adam19	a disintegrin and metallopeptidase domain 19 (meltrin beta)	0.279	Mouse
Jak2	Janus kinase 2	0.278
Rap1b	RAS related protein 1b	0.278
Card11	caspase recruitment domain family, member 11	0.277
Neurog3	neurogenin 3	0.277	Mouse
Cd2ap	CD2-associated protein	0.276
Hspa1b	heat shock protein 1B	0.275
Casp1	caspase 1	0.274	Mouse Rat Fly
App	amyloid beta (A4) precursor protein	0.274
Il10ra	interleukin 10 receptor, alpha	0.274
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.273
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.273
Prph	peripherin	0.273
Vhl	von Hippel-Lindau tumor suppressor	0.272
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.272	Mouse
Inhbb	inhibin beta-B	0.271
Btk	Bruton agammaglobulinemia tyrosine kinase	0.271	Mouse
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.269
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.268
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.267
Anxa4	annexin A4	0.267	Mouse
Lag3	lymphocyte-activation gene 3	0.266
Lif	leukemia inhibitory factor	0.265
Itgal	integrin alpha L	0.265
Xiap	X-linked inhibitor of apoptosis	0.265
Fyn	Fyn proto-oncogene	0.264	Mouse
Tbx2	T-box 2	0.264
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.263
Il1b	interleukin 1 beta	0.263
Ccrl2	chemokine (C-C motif) receptor-like 2	0.262
Cdk2	cyclin-dependent kinase 2	0.262
Dtx1	deltex 1 homolog (Drosophila)	0.259
Kcnj6	potassium inwardly-rectifying channel, subfamily J, member 6	0.258
Mecom	MDS1 and EVI1 complex locus	0.258
Ccr6	chemokine (C-C motif) receptor 6	0.257
Tgif1	TGFB-induced factor homeobox 1	0.257
Ifnar1	interferon (alpha and beta) receptor 1	0.257
Stx1a	syntaxin 1A (brain)	0.256
Prlr	prolactin receptor	0.254
Plcg1	phospholipase C, gamma 1	0.254
Il27ra	interleukin 27 receptor, alpha	0.254
Itga5	integrin alpha 5 (fibronectin receptor alpha)	0.254
Adam11	a disintegrin and metallopeptidase domain 11	0.253	Mouse
Hdac4	histone deacetylase 4	0.253	Rat
Twist1	twist homolog 1 (Drosophila)	0.252	Mouse
Ldb1	LIM domain binding 1	0.252
Mab21l2	mab-21-like 2 (C. elegans)	0.252
Wls	wntless homolog (Drosophila)	0.251
Fgf7	fibroblast growth factor 7	0.251
Foxa2	forkhead box A2	0.247	Fly
Pitx2	paired-like homeodomain transcription factor 2	0.246
Ndfip1	Nedd4 family interacting protein 1	0.246
Capza3	capping protein (actin filament) muscle Z-line, alpha 3	0.244
Smad6	MAD homolog 6 (Drosophila)	0.243
Sox4	SRY-box containing gene 4	0.243	Human
Il2rg	interleukin 2 receptor, gamma chain	0.243
Lta	lymphotoxin A	0.243	Mouse Rat
Lrp5	low density lipoprotein receptor-related protein 5	0.242	Mouse
Tnfrsf13c	tumor necrosis factor receptor superfamily, member 13c	0.242
Wnt3a	wingless-related MMTV integration site 3A	0.241
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.241
Shc1	src homology 2 domain-containing transforming protein C1	0.240
Idua	iduronidase, alpha-L-	0.239
Emx1	empty spiracles homolog 1 (Drosophila)	0.239
Fadd	Fas (TNFRSF6)-associated via death domain	0.238
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.238
Fgf15	fibroblast growth factor 15	0.238
Smad7	MAD homolog 7 (Drosophila)	0.238
Mfap2	microfibrillar-associated protein 2	0.237
Prkcc	protein kinase C, gamma	0.236	Mouse
Tbx15	T-box 15	0.236
Wnt6	wingless-related MMTV integration site 6	0.234	Mouse
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.234
Akap12	A kinase (PRKA) anchor protein (gravin) 12	0.234
Plaur	plasminogen activator, urokinase receptor	0.234
Ikzf1	IKAROS family zinc finger 1	0.233
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.233
Fzd6	frizzled homolog 6 (Drosophila)	0.232
Camk2b	calcium/calmodulin-dependent protein kinase II, beta	0.232
Phldb1	pleckstrin homology-like domain, family B, member 1	0.232
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.231
Lamc1	laminin, gamma 1	0.231
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.230
Egfr	epidermal growth factor receptor	0.230
Egr2	early growth response 2	0.230
Epha6	Eph receptor A6	0.230	Mouse
Igbp1	immunoglobulin (CD79A) binding protein 1	0.229
Vcp	valosin containing protein	0.229
Krt17	keratin 17	0.229
Cdc42ep1	CDC42 effector protein (Rho GTPase binding) 1	0.228
Epha4	Eph receptor A4	0.228	Mouse
Fzd8	frizzled homolog 8 (Drosophila)	0.227
Stx1b	syntaxin 1B	0.226
Entpd2	ectonucleoside triphosphate diphosphohydrolase 2	0.225
Vcl	vinculin	0.225	Mouse
Dnm1	dynamin 1	0.225	Worm
Ctsk	cathepsin K	0.225
Mobkl1b	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.224
Itgb5	integrin beta 5	0.223
Arhgap1	Rho GTPase activating protein 1	0.223
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.222
Axin2	axin2	0.222	Human
Hand1	heart and neural crest derivatives expressed transcript 1	0.222	Mouse
Xpa	xeroderma pigmentosum, complementation group A	0.221
Cacna2d3	calcium channel, voltage-dependent, alpha2/delta subunit 3	0.220
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.220
S100a6	S100 calcium binding protein A6 (calcyclin)	0.220
Icam5	intercellular adhesion molecule 5, telencephalin	0.220
Il6	interleukin 6	0.219	Human
Cst3	cystatin C	0.218
Lepr	leptin receptor	0.218
Madcam1	mucosal vascular addressin cell adhesion molecule 1	0.218
Sat1	spermidine/spermine N1-acetyl transferase 1	0.217
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.217
Sertad1	SERTA domain containing 1	0.217
Ccr4	chemokine (C-C motif) receptor 4	0.217
Rbl1	retinoblastoma-like 1 (p107)	0.217
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.217
Osmr	oncostatin M receptor	0.217
Sptlc2	serine palmitoyltransferase, long chain base subunit 2	0.217
Icos	inducible T-cell co-stimulator	0.216
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.215
Xcl1	chemokine (C motif) ligand 1	0.214	Mouse
Cxcr7	chemokine (C-X-C motif) receptor 7	0.213
Tead2	TEA domain family member 2	0.213
Gabrb3	gamma-aminobutyric acid (GABA) A receptor, subunit beta 3	0.213
Cdx1	caudal type homeobox 1	0.213
Gpr3	G-protein coupled receptor 3	0.212
Klf2	Kruppel-like factor 2 (lung)	0.212
Fjx1	four jointed box 1 (Drosophila)	0.212
Tcf15	transcription factor 15	0.211	Mouse
Sp3	trans-acting transcription factor 3	0.211
Reg3a	regenerating islet-derived 3 alpha	0.210
Fbxw7	F-box and WD-40 domain protein 7	0.209
Lhx6	LIM homeobox protein 6	0.209
Ccr2	chemokine (C-C motif) receptor 2	0.209
Nbn	nibrin	0.209
Gas1	growth arrest specific 1	0.209
Clec4d	C-type lectin domain family 4, member d	0.209
Tmeff2	transmembrane protein with EGF-like and two follistatin-like domains 2	0.208
Irf8	interferon regulatory factor 8	0.208
Il4ra	interleukin 4 receptor, alpha	0.208
Capn2	calpain 2	0.208	Mouse Worm
Fosl2	fos-like antigen 2	0.208
Slfn4	schlafen 4	0.208
Bnc1	basonuclin 1	0.207
Pstpip1	proline-serine-threonine phosphatase-interacting protein 1	0.207
Msn	moesin	0.207
Insr	insulin receptor	0.205
Mib1	mindbomb homolog 1 (Drosophila)	0.205
Fcgr1	Fc receptor, IgG, high affinity I	0.205
Gfpt2	glutamine fructose-6-phosphate transaminase 2	0.204
Ppp2ca	protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform	0.203	Rat
Snai1	snail homolog 1 (Drosophila)	0.202
Aicda	activation-induced cytidine deaminase	0.202
Daxx	Fas death domain-associated protein	0.201
Hoxc9	homeobox C9	0.201
Plxna3	plexin A3	0.201
Irf4	interferon regulatory factor 4	0.201
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.201
Skp1a	S-phase kinase-associated protein 1A	0.200
Myod1	myogenic differentiation 1	0.200
Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.200
Rin2	Ras and Rab interactor 2	0.200
Pls3	plastin 3 (T-isoform)	0.199
Vax2	ventral anterior homeobox containing gene 2	0.199
Fbxo11	F-box protein 11	0.199	Worm
Chrm1	cholinergic receptor, muscarinic 1, CNS	0.199
Mapkapk2	MAP kinase-activated protein kinase 2	0.198
Hr	hairless	0.197
Cbl	Casitas B-lineage lymphoma	0.197
Icam1	intercellular adhesion molecule 1	0.196
Ccne2	cyclin E2	0.195	Fly
Tuba1a	tubulin, alpha 1A	0.195
Hoxa11	homeobox A11	0.195
Snap25	synaptosomal-associated protein 25	0.194
Dab1	disabled homolog 1 (Drosophila)	0.194
Dmpk	dystrophia myotonica-protein kinase	0.194
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.194
Bcl11b	B-cell leukemia/lymphoma 11B	0.193
Gata6	GATA binding protein 6	0.193
Nptn	neuroplastin	0.193
Sdcbp	syndecan binding protein	0.193
Pnpla2	patatin-like phospholipase domain containing 2	0.193
Birc3	baculoviral IAP repeat-containing 3	0.193
Stat5b	signal transducer and activator of transcription 5B	0.192	Mouse
Mapk3	mitogen-activated protein kinase 3	0.192
Tcf7	transcription factor 7, T-cell specific	0.192	Mouse
Lrp6	low density lipoprotein receptor-related protein 6	0.192
Psen2	presenilin 2	0.191
Wwtr1	WW domain containing transcription regulator 1	0.191
Hoxa10	homeobox A10	0.191
Fgf9	fibroblast growth factor 9	0.191
Mfn2	mitofusin 2	0.190
Tiparp	TCDD-inducible poly(ADP-ribose) polymerase	0.190
Mas1	MAS1 oncogene	0.190
Dmgdh	dimethylglycine dehydrogenase precursor	0.189
Vav2	vav 2 oncogene	0.189
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.188
Vdr	vitamin D receptor	0.188
Hspa8	heat shock protein 8	0.187
Per3	period homolog 3 (Drosophila)	0.187
Neurod1	neurogenic differentiation 1	0.187
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.187
Tax1bp3	Tax1 (human T-cell leukemia virus type I) binding protein 3	0.187
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.186	Mouse
Pycard	PYD and CARD domain containing	0.186
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.186
Tcf3	transcription factor 3	0.185	Worm
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.185
Mtor	mechanistic target of rapamycin (serine/threonine kinase)	0.184
Kif1b	kinesin family member 1B	0.184	Worm
Pou2af1	POU domain, class 2, associating factor 1	0.184
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.183
Cav1	caveolin 1, caveolae protein	0.183	Human
Coro1b	coronin, actin binding protein 1B	0.183
Prkd2	protein kinase D2	0.182
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.182
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.181	Mouse
Amhr2	anti-Mullerian hormone type 2 receptor	0.181	Mouse
Cd160	CD160 antigen	0.181
Traf2	TNF receptor-associated factor 2	0.181	Human
Fzd2	frizzled homolog 2 (Drosophila)	0.181
Atp5b	ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit	0.180
Tert	telomerase reverse transcriptase	0.180
Ptpn12	protein tyrosine phosphatase, non-receptor type 12	0.180
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.180
Sox2	SRY-box containing gene 2	0.180
Serpinb6a	serine (or cysteine) peptidase inhibitor, clade B, member 6a	0.180
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.179
Odz4	odd Oz/ten-m homolog 4 (Drosophila)	0.179
Ltbp2	latent transforming growth factor beta binding protein 2	0.179
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.179
Lgals3	lectin, galactose binding, soluble 3	0.178
Mta1	metastasis associated 1	0.178
Fmnl1	formin-like 1	0.178
Acd	adrenocortical dysplasia	0.178
Ets1	E26 avian leukemia oncogene 1, 5' domain	0.177
Mmp13	matrix metallopeptidase 13	0.177	Mouse
Hoxb5	homeobox B5	0.177
S100a11	S100 calcium binding protein A11 (calgizzarin)	0.176
F3	coagulation factor III	0.176	Human
Wnt7b	wingless-related MMTV integration site 7B	0.176	Mouse
Sp1	trans-acting transcription factor 1	0.176
Ctnna2	catenin (cadherin associated protein), alpha 2	0.175	Mouse
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.175
Mme	membrane metallo endopeptidase	0.175
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.174
Stim2	stromal interaction molecule 2	0.174
Cmklr1	chemokine-like receptor 1	0.173
Calca	calcitonin/calcitonin-related polypeptide, alpha	0.173
Esr1	estrogen receptor 1 (alpha)	0.173
Zfp36l1	zinc finger protein 36, C3H type-like 1	0.173
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.173
C3	complement component 3	0.173
Amotl2	angiomotin-like 2	0.172
Cyp1b1	cytochrome P450, family 1, subfamily b, polypeptide 1	0.172
Hoxb3	homeobox B3	0.171
Cst7	cystatin F (leukocystatin)	0.171
Chrnb2	cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)	0.171
Chrng	cholinergic receptor, nicotinic, gamma polypeptide	0.171
Irf9	interferon regulatory factor 9	0.170
Hipk3	homeodomain interacting protein kinase 3	0.170
L1cam	L1 cell adhesion molecule	0.170
Nkx3-2	NK3 homeobox 2	0.170
Cd81	CD81 antigen	0.169
Angptl2	angiopoietin-like 2	0.169
Npy	neuropeptide Y	0.169
Stk3	serine/threonine kinase 3 (Ste20, yeast homolog)	0.169
Prss39	protease, serine, 39	0.169
Mefv	Mediterranean fever	0.169
Ncor2	nuclear receptor co-repressor 2	0.169
Dlk1	delta-like 1 homolog (Drosophila)	0.168
Mark1	MAP/microtubule affinity-regulating kinase 1	0.168
Procr	protein C receptor, endothelial	0.167
Klf10	Kruppel-like factor 10	0.167	Worm
Pou3f1	POU domain, class 3, transcription factor 1	0.167	Mouse
Gbp5	guanylate binding protein 5	0.167
Cdx2	caudal type homeobox 2	0.167
Agtr2	angiotensin II receptor, type 2	0.166	Human
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.165	Human
Sfpi1	SFFV proviral integration 1	0.164
Ptpn2	protein tyrosine phosphatase, non-receptor type 2	0.164
Hdac5	histone deacetylase 5	0.164
Ywhaq	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.164
Tcrb	T-cell receptor beta chain	0.163
Emp1	epithelial membrane protein 1	0.163
Wnt5a	wingless-related MMTV integration site 5A	0.163
Stat6	signal transducer and activator of transcription 6	0.162	Mouse
Tnfaip6	tumor necrosis factor alpha induced protein 6	0.162
Gdf1	growth differentiation factor 1	0.161
Ggt5	gamma-glutamyltransferase 5	0.161
Cd28	CD28 antigen	0.161
Gdf15	growth differentiation factor 15	0.161
Tlr2	toll-like receptor 2	0.161
Was	Wiskott-Aldrich syndrome homolog (human)	0.160
Fnip1	folliculin interacting protein 1	0.160
Masp1	mannan-binding lectin serine peptidase 1	0.160
Prkag1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	0.160
Il1rn	interleukin 1 receptor antagonist	0.159
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.159	Human
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.159	Mouse
Rora	RAR-related orphan receptor alpha	0.159
Phox2a	paired-like homeobox 2a	0.158
Sema4f	sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain	0.158
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.157
Aim2	absent in melanoma 2	0.157
Plin4	perilipin 4	0.156
Kif5a	kinesin family member 5A	0.156	Worm
Bmper	BMP-binding endothelial regulator	0.156
Ostf1	osteoclast stimulating factor 1	0.156
Clgn	calmegin	0.156
Sh3kbp1	SH3-domain kinase binding protein 1	0.156
Junb	Jun-B oncogene	0.156
Smarcd1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.155
Nptx1	neuronal pentraxin 1	0.155
Clca3	chloride channel calcium activated 3	0.155
Zp1	zona pellucida glycoprotein 1	0.154
Cast	calpastatin	0.154
Wnt7a	wingless-related MMTV integration site 7A	0.153	Mouse
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.153
Eda	ectodysplasin-A	0.153
Srpx	sushi-repeat-containing protein	0.153
Mapk12	mitogen-activated protein kinase 12	0.153	Mouse
Spag9	sperm associated antigen 9	0.152
Nedd9	neural precursor cell expressed, developmentally down-regulated gene 9	0.152
Pbx1	pre B-cell leukemia transcription factor 1	0.152
Ina	internexin neuronal intermediate filament protein, alpha	0.152
Atp9a	ATPase, class II, type 9A	0.151
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.151
Il4	interleukin 4	0.151
Pfkm	phosphofructokinase, muscle	0.151
Mycl1	v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)	0.151	Mouse
Tbx21	T-box 21	0.151
Pax8	paired box gene 8	0.150
Robo3	roundabout homolog 3 (Drosophila)	0.150
Efnb2	ephrin B2	0.150
Rps2	ribosomal protein S2	0.150
Lyve1	lymphatic vessel endothelial hyaluronan receptor 1	0.150
Gpr50	G-protein-coupled receptor 50	0.149
Vav3	vav 3 oncogene	0.149
Mta2	metastasis-associated gene family, member 2	0.148
Zfp651	zinc finger protein 651	0.148
Ctgf	connective tissue growth factor	0.148	Mouse Rat
Hoxb1	homeobox B1	0.148
Mknk2	MAP kinase-interacting serine/threonine kinase 2	0.147
Dppa3	developmental pluripotency-associated 3	0.147
Lbr	lamin B receptor	0.147
Timp3	tissue inhibitor of metalloproteinase 3	0.147
Cd97	CD97 antigen	0.147
Anapc2	anaphase promoting complex subunit 2	0.147
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.147
Col4a6	collagen, type IV, alpha 6	0.147
Scn1a	sodium channel, voltage-gated, type I, alpha	0.147
Bclaf1	BCL2-associated transcription factor 1	0.146	Human
Atoh7	atonal homolog 7 (Drosophila)	0.146	Mouse
Fgf17	fibroblast growth factor 17	0.146
Gnao1	guanine nucleotide binding protein, alpha O	0.146
Capn1	calpain 1	0.146	Mouse Worm
Dnajb4	DnaJ (Hsp40) homolog, subfamily B, member 4	0.146
Gsk3b	glycogen synthase kinase 3 beta	0.145
Mgat3	mannoside acetylglucosaminyltransferase 3	0.145
Hoxd8	homeobox D8	0.145
Mapt	microtubule-associated protein tau	0.145
Mapk1	mitogen-activated protein kinase 1	0.144
Oprk1	opioid receptor, kappa 1	0.144
P4ha1	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide	0.144
Pcsk1	proprotein convertase subtilisin/kexin type 1	0.144
Kcnk4	potassium channel, subfamily K, member 4	0.144
Fgf4	fibroblast growth factor 4	0.143
Apbb1	amyloid beta (A4) precursor protein-binding, family B, member 1	0.143	Human Mouse
Sumo1	SMT3 suppressor of mif two 3 homolog 1 (yeast)	0.143
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.143
Atp6v0d1	ATPase, H+ transporting, lysosomal V0 subunit D1	0.143
Spib	Spi-B transcription factor (Spi-1/PU.1 related)	0.142
Inppl1	inositol polyphosphate phosphatase-like 1	0.142	Mouse
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.142
Leprot	leptin receptor overlapping transcript	0.142
Banp	BTG3 associated nuclear protein	0.142
Sez6l	seizure related 6 homolog like	0.141
Neurog1	neurogenin 1	0.141	Mouse
Pax1	paired box gene 1	0.141
Krt71	keratin 71	0.140
Il11	interleukin 11	0.140
Prkaca	protein kinase, cAMP dependent, catalytic, alpha	0.140
Gna11	guanine nucleotide binding protein, alpha 11	0.140
Bcl6b	B-cell CLL/lymphoma 6, member B	0.140
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.140
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.140
Pdpk1	3-phosphoinositide dependent protein kinase 1	0.139
Pax7	paired box gene 7	0.139
Fxyd7	FXYD domain-containing ion transport regulator 7	0.139
Tgfbr3	transforming growth factor, beta receptor III	0.138
Calb2	calbindin 2	0.138
Tfam	transcription factor A, mitochondrial	0.138
Htr4	5 hydroxytryptamine (serotonin) receptor 4	0.137
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.137
Mybl2	myeloblastosis oncogene-like 2	0.137
Ooep	oocyte expressed protein homolog (dog)	0.137
Plcb3	phospholipase C, beta 3	0.137
Pacsin1	protein kinase C and casein kinase substrate in neurons 1	0.137
Eng	endoglin	0.137
Gli1	GLI-Kruppel family member GLI1	0.136	Worm
Leprel4	leprecan-like 4	0.136
Camk2d	calcium/calmodulin-dependent protein kinase II, delta	0.136	Mouse
Casp3	caspase 3	0.136
Pnoc	prepronociceptin	0.136
Ptpre	protein tyrosine phosphatase, receptor type, E	0.135	Mouse
Arid4a	AT rich interactive domain 4A (RBP1-like)	0.135
Tbk1	TANK-binding kinase 1	0.135	Fly
Lox	lysyl oxidase	0.135
Vangl2	vang-like 2 (van gogh, Drosophila)	0.135
Tcrd	T-cell receptor delta chain	0.135
Gpr98	G protein-coupled receptor 98	0.135
Prss23	protease, serine, 23	0.135
Cyld	cylindromatosis (turban tumor syndrome)	0.135	Human
Otog	otogelin	0.135	Mouse
Cyp24a1	cytochrome P450, family 24, subfamily a, polypeptide 1	0.134
Galr2	galanin receptor 2	0.134
Pofut1	protein O-fucosyltransferase 1	0.134
Nfix	nuclear factor I/X	0.134
Nlrp3	NLR family, pyrin domain containing 3	0.134
Npr3	natriuretic peptide receptor 3	0.134
P2rx2	purinergic receptor P2X, ligand-gated ion channel, 2	0.134	Mouse
Plagl2	pleiomorphic adenoma gene-like 2	0.133
H2-Oa	histocompatibility 2, O region alpha locus	0.133
Rpl24	ribosomal protein L24	0.133
Mmp11	matrix metallopeptidase 11	0.133	Mouse
Atp7b	ATPase, Cu++ transporting, beta polypeptide	0.133
Ghrl	ghrelin	0.132
Apba2	amyloid beta (A4) precursor protein-binding, family A, member 2	0.132
Ate1	arginyltransferase 1	0.132
Nhedc2	Na+/H+ exchanger domain containing 2	0.132
Gja3	gap junction protein, alpha 3	0.132
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.132
Mapk11	mitogen-activated protein kinase 11	0.132	Mouse
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.131
Prkar1b	protein kinase, cAMP dependent regulatory, type I beta	0.131
Fzd7	frizzled homolog 7 (Drosophila)	0.131
Col4a3	collagen, type IV, alpha 3	0.131	Human
Rnf112	ring finger protein 112	0.131
Zfp362	zinc finger protein 362	0.131
Hoxa3	homeobox A3	0.130
Aff4	AF4/FMR2 family, member 4	0.130
F2r	coagulation factor II (thrombin) receptor	0.130	Human
Pnmt	phenylethanolamine-N-methyltransferase	0.130
Ptms	parathymosin	0.129
Foxo3	forkhead box O3	0.129	Human Worm
Fstl1	follistatin-like 1	0.129
Zfp316	zinc finger protein 316	0.129
Ngf	nerve growth factor	0.128
Gem	GTP binding protein (gene overexpressed in skeletal muscle)	0.128
Rb1cc1	RB1-inducible coiled-coil 1	0.128