IMP
Process View
nuclear transcribed mrna catabolic process deadenylation dependent decay
A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "nuclear transcribed mrna catabolic process deadenylation dependent decay"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Eif2c2 | eukaryotic translation initiation factor 2C, 2 | 1.000 | ||
| Ddx6 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 | 0.984 | Yeast | |
| Tnrc6b | trinucleotide repeat containing 6b | 0.744 | ||
| Mll3 | myeloid/lymphoid or mixed-lineage leukemia 3 | 0.667 | ||
| Junb | Jun-B oncogene | 0.634 | ||
| Fos | FBJ osteosarcoma oncogene | 0.598 | ||
| Bptf | bromodomain PHD finger transcription factor | 0.524 | ||
| Dusp1 | dual specificity phosphatase 1 | 0.520 | ||
| Neurl1a | neuralized homolog 1A (Drosophila) | 0.343 | ||
| Egr1 | early growth response 1 | 0.279 | ||
| Zfp36 | zinc finger protein 36 | 0.219 | ||
| Gsk3b | glycogen synthase kinase 3 beta | 0.214 | ||
| Trim32 | tripartite motif-containing 32 | 0.204 | ||
| Nfkbia | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.181 | ||
| Brd4 | bromodomain containing 4 | 0.173 | ||
| Btg2 | B-cell translocation gene 2, anti-proliferative | 0.172 | Human | |
| Btg1 | B-cell translocation gene 1, anti-proliferative | 0.170 | ||
| Cnot6 | CCR4-NOT transcription complex, subunit 6 | 0.145 | Human Mouse Fly | |
| Sp1 | trans-acting transcription factor 1 | 0.123 | ||
| Nr4a1 | nuclear receptor subfamily 4, group A, member 1 | 0.109 | ||
| Actn2 | actinin alpha 2 | 0.108 | ||
| Pard3 | par-3 (partitioning defective 3) homolog (C. elegans) | 0.104 | ||
| Rela | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.096 | ||
| Wnk1 | WNK lysine deficient protein kinase 1 | 0.086 | ||
| Caprin1 | cell cycle associated protein 1 | 0.083 | ||
| Ier2 | immediate early response 2 | 0.083 | ||
| Akap9 | A kinase (PRKA) anchor protein (yotiao) 9 | 0.082 | ||
| Igf1r | insulin-like growth factor I receptor | 0.081 | ||
| Nudcd2 | NudC domain containing 2 | 0.079 | ||
| Irs2 | insulin receptor substrate 2 | 0.077 | ||
| Mll5 | myeloid/lymphoid or mixed-lineage leukemia 5 | 0.072 | ||
| Klf6 | Kruppel-like factor 6 | 0.071 | ||
| Rcor1 | REST corepressor 1 | 0.068 | ||
| Jun | Jun oncogene | 0.067 | ||
| Ldb3 | LIM domain binding 3 | 0.065 | ||
| Trrap | transformation/transcription domain-associated protein | 0.060 | ||
| Mll1 | myeloid/lymphoid or mixed-lineage leukemia 1 | 0.059 | ||
| Ankhd1 | ankyrin repeat and KH domain containing 1 | 0.056 | ||
| Pum1 | pumilio 1 (Drosophila) | 0.054 | Yeast | |
| Tnrc6c | trinucleotide repeat containing 6C | 0.052 | Human | |
| Pabpc1 | poly(A) binding protein, cytoplasmic 1 | 0.047 | ||
| Tnfaip3 | tumor necrosis factor, alpha-induced protein 3 | 0.047 | ||
| Brd2 | bromodomain containing 2 | 0.045 | ||
| Rc3h1 | RING CCCH (C3H) domains 1 | 0.044 | ||
| Elavl1 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) | 0.043 | ||
| Vegfa | vascular endothelial growth factor A | 0.042 | ||
| Akt2 | thymoma viral proto-oncogene 2 | 0.042 | Yeast | |
| Nupl1 | nucleoporin like 1 | 0.038 | ||
| Celf1 | CUGBP, Elav-like family member 1 | 0.038 | ||
| Cd28 | CD28 antigen | 0.038 | ||
| Csnk2a1 | casein kinase 2, alpha 1 polypeptide | 0.037 | ||
| Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.037 | ||
| Nfatc3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.037 | ||
| Arid1a | AT rich interactive domain 1A (SWI-like) | 0.036 | ||
| Gm2223 | predicted pseudogene 2223 | 0.035 | ||
| Rasal1 | RAS protein activator like 1 (GAP1 like) | 0.034 | ||
| Ppp1r15a | protein phosphatase 1, regulatory (inhibitor) subunit 15A | 0.034 | ||
| Kpnb1 | karyopherin (importin) beta 1 | 0.034 | ||
| Cnot7 | CCR4-NOT transcription complex, subunit 7 | 0.034 | ||
| Rfx7 | regulatory factor X, 7 | 0.033 | ||
| Ncoa1 | nuclear receptor coactivator 1 | 0.033 | ||
| Smad1 | MAD homolog 1 (Drosophila) | 0.033 | ||
| Mafk | v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian) | 0.033 | ||
| Map3k1 | mitogen-activated protein kinase kinase kinase 1 | 0.032 | ||
| Bmpr2 | bone morphogenic protein receptor, type II (serine/threonine kinase) | 0.031 | ||
| Klf7 | Kruppel-like factor 7 (ubiquitous) | 0.030 | ||
| Vhl | von Hippel-Lindau tumor suppressor | 0.028 | ||
| Irf2bp2 | interferon regulatory factor 2 binding protein 2 | 0.028 | ||
| Atf3 | activating transcription factor 3 | 0.027 | ||
| Purb | purine rich element binding protein B | 0.027 | ||
| Ep300 | E1A binding protein p300 | 0.027 | ||
| Arid2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.027 | ||
| Akt1 | thymoma viral proto-oncogene 1 | 0.027 | Yeast | |
| Tnrc6a | trinucleotide repeat containing 6a | 0.026 | ||
| Atp2b1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.026 | ||
| Hsp90ab1 | heat shock protein 90 alpha (cytosolic), class B member 1 | 0.025 | ||
| Rhog | ras homolog gene family, member G | 0.025 | ||
| Chd4 | chromodomain helicase DNA binding protein 4 | 0.025 | ||
| Xpot | exportin, tRNA (nuclear export receptor for tRNAs) | 0.024 | ||
| D19Wsu162e | DNA segment, Chr 19, Wayne State University 162, expressed | 0.024 | ||
| Dyrk1a | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a | 0.022 | ||
| Smad4 | MAD homolog 4 (Drosophila) | 0.022 | ||
| Mael | maelstrom homolog (Drosophila) | 0.022 | ||
| Pafah1b2 | platelet-activating factor acetylhydrolase, isoform 1b, subunit 2 | 0.022 | ||
| Pknox1 | Pbx/knotted 1 homeobox | 0.022 | ||
| Nanos2 | nanos homolog 2 (Drosophila) | 0.021 | ||
| Man1a2 | mannosidase, alpha, class 1A, member 2 | 0.021 | ||
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.021 | ||
| Ehmt2 | euchromatic histone lysine N-methyltransferase 2 | 0.020 | ||
| Taok1 | TAO kinase 1 | 0.020 | ||
| Bcl2 | B-cell leukemia/lymphoma 2 | 0.020 | ||
| Klf3 | Kruppel-like factor 3 (basic) | 0.020 | ||
| Zmym5 | zinc finger, MYM-type 5 | 0.020 | ||
| Wdr36 | WD repeat domain 36 | 0.019 | ||
| Wdr77 | WD repeat domain 77 | 0.019 | ||
| Kctd20 | potassium channel tetramerisation domain containing 20 | 0.019 | ||
| Tnfrsf13b | tumor necrosis factor receptor superfamily, member 13b | 0.019 | ||
| Map3k5 | mitogen-activated protein kinase kinase kinase 5 | 0.019 | ||
| Gspt1 | G1 to S phase transition 1 | 0.019 | Yeast | |
| Chd1l | chromodomain helicase DNA binding protein 1-like | 0.018 | ||
| Foxo3 | forkhead box O3 | 0.018 | ||
| Midn | midnolin | 0.018 | ||
| Actb | actin, beta | 0.018 | ||
| Adam10 | a disintegrin and metallopeptidase domain 10 | 0.017 | ||
| Nr2c2 | nuclear receptor subfamily 2, group C, member 2 | 0.017 | ||
| Scaf8 | SR-related CTD-associated factor 8 | 0.017 | ||
| Dhx36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | 0.017 | ||
| Lep | leptin | 0.017 | ||
| Foxo1 | forkhead box O1 | 0.017 | ||
| Med13l | mediator complex subunit 13-like | 0.017 | ||
| Ddx46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.016 | ||
| Znrf2 | zinc and ring finger 2 | 0.016 | ||
| Phlpp1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.016 | ||
| Crebbp | CREB binding protein | 0.016 | ||
| Prkce | protein kinase C, epsilon | 0.015 | ||
| Gpatch8 | G patch domain containing 8 | 0.015 | ||
| Pdcd4 | programmed cell death 4 | 0.015 | ||
| Igh | immunoglobulin heavy chain complex | 0.015 | ||
| Casp2 | caspase 2 | 0.015 | ||
| Ywhaz | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.015 | ||
| Pparg | peroxisome proliferator activated receptor gamma | 0.015 | ||
| Sp4 | trans-acting transcription factor 4 | 0.015 | ||
| Synrg | synergin, gamma | 0.014 | ||
| Mapkap1 | mitogen-activated protein kinase associated protein 1 | 0.014 | ||
| Actn4 | actinin alpha 4 | 0.014 | ||
| Elp3 | elongation protein 3 homolog (S. cerevisiae) | 0.014 | ||
| Tob2 | transducer of ERBB2, 2 | 0.013 | ||
| 2210419D22Rik | RIKEN cDNA 2210419D22 gene | 0.013 | ||
| Utp6 | UTP6, small subunit (SSU) processome component, homolog (yeast) | 0.013 | ||
| Pim1 | proviral integration site 1 | 0.013 | ||
| Nfkbiz | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.013 | ||
| Kdm6a | 4lysine (K)-specific demethylase 6A | 0.013 | ||
| Klf4 | Kruppel-like factor 4 (gut) | 0.013 | ||
| Cbll1 | Casitas B-lineage lymphoma-like 1 | 0.013 | ||
| Cand1 | cullin associated and neddylation disassociated 1 | 0.013 | ||
| Crb2 | crumbs homolog 2 (Drosophila) | 0.013 | ||
| Tbl1x | transducin (beta)-like 1 X-linked | 0.013 | ||
| Mau2 | MAU2 chromatid cohesion factor homolog (C. elegans) | 0.012 | ||
| Rsf1 | remodeling and spacing factor 1 | 0.012 | ||
| Cd151 | CD151 antigen | 0.012 | ||
| Ccni | cyclin I | 0.012 | ||
| Elf2 | E74-like factor 2 | 0.012 | ||
| Pias2 | protein inhibitor of activated STAT 2 | 0.012 | ||
| Clock | circadian locomotor output cycles kaput | 0.012 | ||
| Pbx2 | pre B-cell leukemia transcription factor 2 | 0.012 | ||
| Ide | insulin degrading enzyme | 0.012 | ||
| Phf21a | PHD finger protein 21A | 0.012 | ||
| Fas | Fas (TNF receptor superfamily member 6) | 0.012 | ||
| Fosb | FBJ osteosarcoma oncogene B | 0.012 | ||
| Eri1 | exoribonuclease 1 | 0.012 | ||
| Hnrnpab | heterogeneous nuclear ribonucleoprotein A/B | 0.011 | ||
| Bzw1 | basic leucine zipper and W2 domains 1 | 0.011 | ||
| Cul4b | cullin 4B | 0.011 | ||
| Ptpn22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.011 | ||
| Kif1b | kinesin family member 1B | 0.011 | ||
| Hnrnpul1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.011 | ||
| Vasp | vasodilator-stimulated phosphoprotein | 0.011 | ||
| Usp10 | ubiquitin specific peptidase 10 | 0.011 | ||
| Tomm40 | translocase of outer mitochondrial membrane 40 homolog (yeast) | 0.011 | ||
| Abce1 | ATP-binding cassette, sub-family E (OABP), member 1 | 0.011 | ||
| Bach2 | BTB and CNC homology 2 | 0.011 | ||
| Tgif1 | TGFB-induced factor homeobox 1 | 0.011 | ||
| Mlf2 | myeloid leukemia factor 2 | 0.011 | ||
| Prpf40a | PRP40 pre-mRNA processing factor 40 homolog A (yeast) | 0.011 | ||
| Peli1 | pellino 1 | 0.011 | ||
| Cnot1 | CCR4-NOT transcription complex, subunit 1 | 0.011 | ||
| Elf1 | E74-like factor 1 | 0.010 | ||
| Crim1 | cysteine rich transmembrane BMP regulator 1 (chordin like) | 0.010 | ||
| Zfp362 | zinc finger protein 362 | 0.010 | ||
| Nipa2 | non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human) | 0.010 | ||
| Pim3 | proviral integration site 3 | 0.010 | ||
| Impad1 | inositol monophosphatase domain containing 1 | 0.010 |