IMP: Integrative Multi-species Prediction

Mus musculus

356 genes annotated in mouse

skeletal system development

The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "skeletal system development"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "skeletal system development" (in gray)

Name	Description	Probability	Func Analog Organism
Gli3	GLI-Kruppel family member GLI3	1.000
Fgfr2	fibroblast growth factor receptor 2	1.000
Shh	sonic hedgehog	1.000
Dlx5	distal-less homeobox 5	1.000
Prrx1	paired related homeobox 1	1.000
Gli2	GLI-Kruppel family member GLI2	1.000
Fgfr3	fibroblast growth factor receptor 3	1.000
Fgfr1	fibroblast growth factor receptor 1	1.000
Ctnnb1	catenin (cadherin associated protein), beta 1	1.000
Pax3	paired box gene 3	1.000	Mouse
Hand1	heart and neural crest derivatives expressed transcript 1	1.000
Bmp4	bone morphogenetic protein 4	1.000
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	1.000
Foxc1	forkhead box C1	0.999
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.999
Trp53	transformation related protein 53	0.999	Mouse
Bmp7	bone morphogenetic protein 7	0.999
Tcfap2a	transcription factor AP-2, alpha	0.999
Rarg	retinoic acid receptor, gamma	0.999
Pitx2	paired-like homeodomain transcription factor 2	0.999
Pbx1	pre B-cell leukemia transcription factor 1	0.999
Eya1	eyes absent 1 homolog (Drosophila)	0.999
Pax9	paired box gene 9	0.999	Mouse
Pax2	paired box gene 2	0.999	Mouse
Otx2	orthodenticle homolog 2 (Drosophila)	0.999
Vegfa	vascular endothelial growth factor A	0.999
Prrx2	paired related homeobox 2	0.999
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.999
Sox9	SRY-box containing gene 9	0.999
Hand2	heart and neural crest derivatives expressed transcript 2	0.999
Msx1	homeobox, msh-like 1	0.998
Twist2	twist homolog 2 (Drosophila)	0.998
Hoxa1	homeobox A1	0.998	Human Mouse
Fgf8	fibroblast growth factor 8	0.998	Zebrafish Mouse
Meox2	mesenchyme homeobox 2	0.998
Pten	phosphatase and tensin homolog	0.998
Hoxd11	homeobox D11	0.998
Tgfb2	transforming growth factor, beta 2	0.997
Fgf10	fibroblast growth factor 10	0.997	Mouse
Tbx1	T-box 1	0.996
Col2a1	collagen, type II, alpha 1	0.996
Col1a1	collagen, type I, alpha 1	0.996
Foxc2	forkhead box C2	0.996
Hoxa10	homeobox A10	0.995
Smo	smoothened homolog (Drosophila)	0.995	Zebrafish
Alx4	aristaless-like homeobox 4	0.995
Nog	noggin	0.994
Zeb1	zinc finger E-box binding homeobox 1	0.994
Lmx1a	LIM homeobox transcription factor 1 alpha	0.993	Mouse
Runx2	runt related transcription factor 2	0.993
Psen1	presenilin 1	0.992
Tgfbr2	transforming growth factor, beta receptor II	0.992
Hoxa13	homeobox A13	0.991	Mouse
Gsc	goosecoid homeobox	0.990
Wnt3a	wingless-related MMTV integration site 3A	0.989	Mouse
Fbn1	fibrillin 1	0.989	Human Mouse
Hoxd13	homeobox D13	0.988
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.985
Pitx1	paired-like homeodomain transcription factor 1	0.984
Twist1	twist homolog 1 (Drosophila)	0.983
Vangl2	vang-like 2 (van gogh, Drosophila)	0.981
Pkd1	polycystic kidney disease 1 homolog	0.981
Alx3	aristaless-like homeobox 3	0.980
Rarb	retinoic acid receptor, beta	0.979
Chrd	chordin	0.979
Gas1	growth arrest specific 1	0.979
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.978	Mouse
Hoxa11	homeobox A11	0.977
Msx2	homeobox, msh-like 2	0.975
Hoxa2	homeobox A2	0.975
Pthlh	parathyroid hormone-like peptide	0.975
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.974
Wnt5a	wingless-related MMTV integration site 5A	0.970
Axl	AXL receptor tyrosine kinase	0.969	Mouse
Gbx2	gastrulation brain homeobox 2	0.969
Col6a2	collagen, type VI, alpha 2	0.968
Zic3	zinc finger protein of the cerebellum 3	0.966
Rnf2	ring finger protein 2	0.962	Zebrafish
Pax1	paired box gene 1	0.961
Col11a1	collagen, type XI, alpha 1	0.961
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.960
Tbx3	T-box 3	0.957	Human Mouse
Sox2	SRY-box containing gene 2	0.957	Mouse
Sfrp2	secreted frizzled-related protein 2	0.956
Tbx15	T-box 15	0.954
Ptch1	patched homolog 1	0.953
Wt1	Wilms tumor 1 homolog	0.951
Hoxb3	homeobox B3	0.949
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.949
Thbs1	thrombospondin 1	0.948
Pou3f3	POU domain, class 3, transcription factor 3	0.947
Neurog3	neurogenin 3	0.946	Mouse
Tcf21	transcription factor 21	0.942
Npr3	natriuretic peptide receptor 3	0.941
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.939
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.939
Alx1	ALX homeobox 1	0.939
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.938
Pax6	paired box gene 6	0.938
Mmp2	matrix metallopeptidase 2	0.933
Sox3	SRY-box containing gene 3	0.933	Mouse
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.933
Acvr2b	activin receptor IIB	0.923
Foxd3	forkhead box D3	0.921	Zebrafish Mouse
Hoxa9	homeobox A9	0.921
Smpd3	sphingomyelin phosphodiesterase 3, neutral	0.921
Fgf18	fibroblast growth factor 18	0.920
Apc	adenomatosis polyposis coli	0.916
Hoxd10	homeobox D10	0.916
Hmx3	H6 homeobox 3	0.906
Neurog2	neurogenin 2	0.904	Mouse
Ret	ret proto-oncogene	0.902
Col1a2	collagen, type I, alpha 2	0.901	Human Mouse
Smad5	MAD homolog 5 (Drosophila)	0.898
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.897
Eln	elastin	0.894
Notch1	Notch gene homolog 1 (Drosophila)	0.891
Ednra	endothelin receptor type A	0.891	Zebrafish
Fzd2	frizzled homolog 2 (Drosophila)	0.890	Mouse
Sox10	SRY-box containing gene 10	0.890	Mouse
Shox2	short stature homeobox 2	0.889
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.888
Hoxd3	homeobox D3	0.885
Fstl1	follistatin-like 1	0.885	Mouse
Dlx6	distal-less homeobox 6	0.884	Mouse
Myod1	myogenic differentiation 1	0.884	Mouse
Hoxa5	homeobox A5	0.883
Mmp24	matrix metallopeptidase 24	0.879	Mouse
T	brachyury	0.878
Mapk14	mitogen-activated protein kinase 14	0.876
Uncx	UNC homeobox	0.876
Sgpl1	sphingosine phosphate lyase 1	0.875
Egr2	early growth response 2	0.875
Pax8	paired box gene 8	0.875	Mouse
Fgf9	fibroblast growth factor 9	0.874
Bcl2	B-cell leukemia/lymphoma 2	0.874
Vdr	vitamin D receptor	0.872
Mstn	myostatin	0.872	Mouse
Nodal	nodal	0.870
Fzd1	frizzled homolog 1 (Drosophila)	0.870	Mouse
Lox	lysyl oxidase	0.870	Zebrafish
Gdnf	glial cell line derived neurotrophic factor	0.869
Meis2	Meis homeobox 2	0.868
Mef2d	myocyte enhancer factor 2D	0.866
Robo3	roundabout homolog 3 (Drosophila)	0.865
Hoxb4	homeobox B4	0.864
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.862
Fzd8	frizzled homolog 8 (Drosophila)	0.860	Mouse
Hoxa3	homeobox A3	0.859
Foxa2	forkhead box A2	0.859	Mouse
Efnb1	ephrin B1	0.857
Neurog1	neurogenin 1	0.856	Mouse
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.856
Pitx3	paired-like homeodomain transcription factor 3	0.854	Mouse
Ece1	endothelin converting enzyme 1	0.853
Bbs4	Bardet-Biedl syndrome 4 (human)	0.853
Fgf15	fibroblast growth factor 15	0.852
Chuk	conserved helix-loop-helix ubiquitous kinase	0.851
Efna2	ephrin A2	0.851
Bmp2	bone morphogenetic protein 2	0.847
Gdf5	growth differentiation factor 5	0.846
Hoxd9	homeobox D9	0.846
Fgf4	fibroblast growth factor 4	0.845
Emx2	empty spiracles homolog 2 (Drosophila)	0.844
Robo1	roundabout homolog 1 (Drosophila)	0.842
Notch3	Notch gene homolog 3 (Drosophila)	0.841
Foxf1a	forkhead box F1a	0.840
Bgn	biglycan	0.839
Arx	aristaless related homeobox	0.839	Mouse
Lef1	lymphoid enhancer binding factor 1	0.837
Cer1	cerberus 1 homolog (Xenopus laevis)	0.836
Col12a1	collagen, type XII, alpha 1	0.834
Dhh	desert hedgehog	0.834	Mouse
Tbx2	T-box 2	0.832	Mouse
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.831	Zebrafish
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.830
Mrc2	mannose receptor, C type 2	0.829
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.827
Hoxb1	homeobox B1	0.826
Rybp	RING1 and YY1 binding protein	0.821
Col5a1	collagen, type V, alpha 1	0.820	Mouse
Evx2	even skipped homeotic gene 2 homolog	0.813	Mouse
Bmp5	bone morphogenetic protein 5	0.813
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.812
Lrp6	low density lipoprotein receptor-related protein 6	0.811
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.806	Mouse
Phox2b	paired-like homeobox 2b	0.805	Mouse
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.799
Arid5b	AT rich interactive domain 5B (MRF1-like)	0.799
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.797
Sox11	SRY-box containing gene 11	0.793
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.790	Mouse
Ptk7	PTK7 protein tyrosine kinase 7	0.788
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.788
Hoxc6	homeobox C6	0.785
Fgf3	fibroblast growth factor 3	0.784	Zebrafish Mouse
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.781
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.778	Mouse
Nkx3-2	NK3 homeobox 2	0.777
Igf1	insulin-like growth factor 1	0.777	Human
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.776
Arhgef11	Rho guanine nucleotide exchange factor (GEF) 11	0.775
Gli1	GLI-Kruppel family member GLI1	0.774	Mouse
En1	engrailed 1	0.773
Mybph	myosin binding protein H	0.772
Barx1	BarH-like homeobox 1	0.772	Zebrafish Mouse
Acvr1	activin A receptor, type 1	0.772	Mouse
Emid2	EMI domain containing 2	0.771
Magel2	melanoma antigen, family L, 2	0.768
Hic1	hypermethylated in cancer 1	0.767
Wnt1	wingless-related MMTV integration site 1	0.762	Human Mouse
Col13a1	collagen, type XIII, alpha 1	0.760
Wnt6	wingless-related MMTV integration site 6	0.760	Mouse
Lrp5	low density lipoprotein receptor-related protein 5	0.758
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.753
Apaf1	apoptotic peptidase activating factor 1	0.749
Gpc3	glypican 3	0.746
Matn4	matrilin 4	0.745	Mouse
Wisp1	WNT1 inducible signaling pathway protein 1	0.740	Mouse
Rara	retinoic acid receptor, alpha	0.739
Axin2	axin2	0.732
Csf1	colony stimulating factor 1 (macrophage)	0.731
Bdkrb2	bradykinin receptor, beta 2	0.730
Mef2c	myocyte enhancer factor 2C	0.727
Foxd2	forkhead box D2	0.725	Mouse
Zic2	zinc finger protein of the cerebellum 2	0.724	Zebrafish
Gata4	GATA binding protein 4	0.722
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.722
Pax7	paired box gene 7	0.722
Bglap	bone gamma carboxyglutamate protein	0.722
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.720
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.719
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.716
Pdgfb	platelet derived growth factor, B polypeptide	0.715
Col5a2	collagen, type V, alpha 2	0.714
Snai1	snail homolog 1 (Drosophila)	0.714
Col3a1	collagen, type III, alpha 1	0.714	Mouse Rat
Smad2	MAD homolog 2 (Drosophila)	0.713
Atoh7	atonal homolog 7 (Drosophila)	0.712	Mouse
Hes1	hairy and enhancer of split 1 (Drosophila)	0.711	Mouse
Mdm2	transformed mouse 3T3 cell double minute 2	0.710
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.709
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.708
Lrp1	low density lipoprotein receptor-related protein 1	0.707	Mouse
Lmx1b	LIM homeobox transcription factor 1 beta	0.705	Mouse
Efnb2	ephrin B2	0.705
Efs	embryonal Fyn-associated substrate	0.702
Myog	myogenin	0.698	Mouse
Tbx4	T-box 4	0.697	Mouse
Evx1	even skipped homeotic gene 1 homolog	0.694	Mouse
Hoxb6	homeobox B6	0.693
Slit2	slit homolog 2 (Drosophila)	0.693	Mouse
Ntf3	neurotrophin 3	0.693
Srpx	sushi-repeat-containing protein	0.691
Scn5a	sodium channel, voltage-gated, type V, alpha	0.691
Tlx2	T-cell leukemia, homeobox 2	0.691
Nfia	nuclear factor I/A	0.691	Mouse
Tlx3	T-cell leukemia, homeobox 3	0.690
Osr1	odd-skipped related 1 (Drosophila)	0.690
Bmp1	bone morphogenetic protein 1	0.689	Human
Dlx2	distal-less homeobox 2	0.689
Igfbp5	insulin-like growth factor binding protein 5	0.688
Ltbp2	latent transforming growth factor beta binding protein 2	0.686	Mouse
Kcnj4	potassium inwardly-rectifying channel, subfamily J, member 4	0.685
Smad3	MAD homolog 3 (Drosophila)	0.684
Cdh3	cadherin 3	0.680
Ar	androgen receptor	0.679
Crebbp	CREB binding protein	0.679
Ptf1a	pancreas specific transcription factor, 1a	0.679	Mouse
Ncoa3	nuclear receptor coactivator 3	0.676
Cav1	caveolin 1, caveolae protein	0.676
Meis1	Meis homeobox 1	0.674	Zebrafish
Fat4	FAT tumor suppressor homolog 4 (Drosophila)	0.673
Wnt10b	wingless related MMTV integration site 10b	0.670
Ryr1	ryanodine receptor 1, skeletal muscle	0.664
Hdac5	histone deacetylase 5	0.661	Mouse
Dlx1	distal-less homeobox 1	0.656
Myf5	myogenic factor 5	0.655
Foxa1	forkhead box A1	0.654	Mouse
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.649
Crlf1	cytokine receptor-like factor 1	0.646
Col6a1	collagen, type VI, alpha 1	0.643
Axin1	axin 1	0.641
Zfp503	zinc finger protein 503	0.639
Otp	orthopedia homolog (Drosophila)	0.636
Isl2	insulin related protein 2 (islet 2)	0.634	Mouse
Mdm4	transformed mouse 3T3 cell double minute 4	0.630
Pou2f2	POU domain, class 2, transcription factor 2	0.627
Rdh10	retinol dehydrogenase 10 (all-trans)	0.627
Gata6	GATA binding protein 6	0.625
Foxg1	forkhead box G1	0.624	Mouse
Rax	retina and anterior neural fold homeobox	0.624
Fgf2	fibroblast growth factor 2	0.618	Human Mouse
Fgf5	fibroblast growth factor 5	0.616	Mouse
Jag2	jagged 2	0.615
Sall1	sal-like 1 (Drosophila)	0.608
Wdr19	WD repeat domain 19	0.607
Nhlh1	nescient helix loop helix 1	0.603	Mouse
Lhx3	LIM homeobox protein 3	0.600	Mouse
Bnc1	basonuclin 1	0.600	Mouse
Mmp16	matrix metallopeptidase 16	0.596
Twsg1	twisted gastrulation homolog 1 (Drosophila)	0.595
Lepr	leptin receptor	0.594
Lhx1	LIM homeobox protein 1	0.594
Sall3	sal-like 3 (Drosophila)	0.592
Mpz	myelin protein zero	0.591
Gdf1	growth differentiation factor 1	0.590	Mouse
Tbx5	T-box 5	0.590	Mouse
Gja8	gap junction protein, alpha 8	0.586	Mouse
Syt7	synaptotagmin VII	0.585
Gsk3b	glycogen synthase kinase 3 beta	0.585
Btbd17	BTB (POZ) domain containing 17	0.585
Pou5f1	POU domain, class 5, transcription factor 1	0.582
Emx1	empty spiracles homolog 1 (Drosophila)	0.579
Foxl2	forkhead box L2	0.578	Mouse
Smad6	MAD homolog 6 (Drosophila)	0.578	Mouse
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.578
Agtr2	angiotensin II receptor, type 2	0.577
Hoxa4	homeobox A4	0.577
Islr	immunoglobulin superfamily containing leucine-rich repeat	0.576
Pdx1	pancreatic and duodenal homeobox 1	0.574
Thra	thyroid hormone receptor alpha	0.573
Cxcl12	chemokine (C-X-C motif) ligand 12	0.573
Nkx2-1	NK2 homeobox 1	0.571	Mouse
Adra2a	adrenergic receptor, alpha 2a	0.570
Meox1	mesenchyme homeobox 1	0.568
Ltbp1	latent transforming growth factor beta binding protein 1	0.567	Mouse
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.565
Tnks1bp1	tankyrase 1 binding protein 1	0.564
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.558	Mouse
Inhba	inhibin beta-A	0.556
Ikbkb	inhibitor of kappaB kinase beta	0.555
Gdf3	growth differentiation factor 3	0.552	Mouse
Hoxc4	homeobox C4	0.552
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.550	Mouse
Mn1	meningioma 1	0.549
Msi1	Musashi homolog 1(Drosophila)	0.546
Hoxb5	homeobox B5	0.546
Hmx1	H6 homeobox 1	0.543
Efna4	ephrin A4	0.541
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.540
Eda	ectodysplasin-A	0.539
Vax1	ventral anterior homeobox containing gene 1	0.537
Dmrt1	doublesex and mab-3 related transcription factor 1	0.534	Mouse
Srcin1	SRC kinase signaling inhibitor 1	0.533	Mouse
Htt	huntingtin	0.530	Zebrafish
Nes	nestin	0.523
Bmper	BMP-binding endothelial regulator	0.522
Hoxc9	homeobox C9	0.520
Sall4	sal-like 4 (Drosophila)	0.516
Slit3	slit homolog 3 (Drosophila)	0.516	Mouse
Sox7	SRY-box containing gene 7	0.515	Mouse
Ascl2	achaete-scute complex homolog 2 (Drosophila)	0.515
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.514
Foxh1	forkhead box H1	0.513
Tacr2	tachykinin receptor 2	0.510
Msx3	homeobox, msh-like 3	0.508	Zebrafish Mouse
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.507	Mouse
Tcof1	Treacher Collins Franceschetti syndrome 1, homolog	0.506
Leprel2	leprecan-like 2	0.505
Zfp703	zinc finger protein 703	0.504
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.502
Ldb2	LIM domain binding 2	0.502
Pkd2	polycystic kidney disease 2	0.502	Mouse
Pth1r	parathyroid hormone 1 receptor	0.499
Ephb2	Eph receptor B2	0.499	Mouse
Dlg4	discs, large homolog 4 (Drosophila)	0.498	Mouse
Zic1	zinc finger protein of the cerebellum 1	0.498
Trpm1	transient receptor potential cation channel, subfamily M, member 1	0.495
Gtf2ird1	general transcription factor II I repeat domain-containing 1	0.494
Tal2	T-cell acute lymphocytic leukemia 2	0.493	Mouse
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.492
Notch2	Notch gene homolog 2 (Drosophila)	0.490	Zebrafish
Hoxb9	homeobox B9	0.490
Jag1	jagged 1	0.485	Zebrafish Mouse
Lpar1	lysophosphatidic acid receptor 1	0.480
Cdk5r2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.480
Lrp2	low density lipoprotein receptor-related protein 2	0.479	Mouse
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.476
Pcdh12	protocadherin 12	0.475
Pou3f1	POU domain, class 3, transcription factor 1	0.473
Serpinh1	serine (or cysteine) peptidase inhibitor, clade H, member 1	0.471
Grin2d	glutamate receptor, ionotropic, NMDA2D (epsilon 4)	0.469
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.468
Tgfbr3	transforming growth factor, beta receptor III	0.468
Gdf11	growth differentiation factor 11	0.466
Wnt2b	wingless related MMTV integration site 2b	0.466	Human Mouse
Tiparp	TCDD-inducible poly(ADP-ribose) polymerase	0.464
Grem1	gremlin 1	0.464	Human Mouse
Rem1	rad and gem related GTP binding protein 1	0.464
Ddx60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.464
Htr4	5 hydroxytryptamine (serotonin) receptor 4	0.462
Epha2	Eph receptor A2	0.461
Gnat1	guanine nucleotide binding protein, alpha transducing 1	0.461	Mouse
Ednrb	endothelin receptor type B	0.460
Smad4	MAD homolog 4 (Drosophila)	0.459	Mouse
Fgf17	fibroblast growth factor 17	0.459	Mouse
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.459
Epas1	endothelial PAS domain protein 1	0.458	Mouse
Grik2	glutamate receptor, ionotropic, kainate 2 (beta 2)	0.458
Foxd1	forkhead box D1	0.457	Mouse
Bdnf	brain derived neurotrophic factor	0.457
Fbn2	fibrillin 2	0.455
Epha4	Eph receptor A4	0.455	Mouse
Slit1	slit homolog 1 (Drosophila)	0.454	Mouse
Tgfb1i1	transforming growth factor beta 1 induced transcript 1	0.453
She	src homology 2 domain-containing transforming protein E	0.448
Smoc2	SPARC related modular calcium binding 2	0.446
Dlk1	delta-like 1 homolog (Drosophila)	0.445
Tead3	TEA domain family member 3	0.443
Dll1	delta-like 1 (Drosophila)	0.443	Mouse
Hoxd1	homeobox D1	0.443
Fgfrl1	fibroblast growth factor receptor-like 1	0.442
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.440
Tead4	TEA domain family member 4	0.439
B3gat1	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)	0.438
Fev	FEV (ETS oncogene family)	0.438
Frem1	Fras1 related extracellular matrix protein 1	0.437	Human
Hapln1	hyaluronan and proteoglycan link protein 1	0.437	Mouse
Tef	thyrotroph embryonic factor	0.437
Arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.435
Tcfap2b	transcription factor AP-2 beta	0.435	Zebrafish Mouse
Alox12b	arachidonate 12-lipoxygenase, 12R type	0.435
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.434	Mouse
Gata3	GATA binding protein 3	0.432	Zebrafish
Col22a1	collagen, type XXII, alpha 1	0.431
Nkx2-4	NK2 transcription factor related, locus 4 (Drosophila)	0.431	Mouse
Foxp2	forkhead box P2	0.429
Fzd7	frizzled homolog 7 (Drosophila)	0.428	Mouse
Efna5	ephrin A5	0.428
Edn3	endothelin 3	0.427	Mouse
Kit	kit oncogene	0.427	Mouse
Adrb1	adrenergic receptor, beta 1	0.426
Krt16	keratin 16	0.424
Sulf1	sulfatase 1	0.424
Nkd1	naked cuticle 1 homolog (Drosophila)	0.423
Lmna	lamin A	0.423
Epha3	Eph receptor A3	0.422	Mouse
Gsx2	GS homeobox 2	0.421	Mouse
Lhx5	LIM homeobox protein 5	0.420	Mouse
Hdac1	histone deacetylase 1	0.419
Runx1t1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.417
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.416	Mouse
Apoe	apolipoprotein E	0.416
Itga5	integrin alpha 5 (fibronectin receptor alpha)	0.416	Zebrafish
Schip1	schwannomin interacting protein 1	0.414
Gpr3	G-protein coupled receptor 3	0.414
Grin2a	glutamate receptor, ionotropic, NMDA2A (epsilon 1)	0.414
Grb10	growth factor receptor bound protein 10	0.413
Egfr	epidermal growth factor receptor	0.412
Odz3	odd Oz/ten-m homolog 3 (Drosophila)	0.412
Ctgf	connective tissue growth factor	0.412
Ncor2	nuclear receptor co-repressor 2	0.410
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.409
Dvl3	dishevelled 3, dsh homolog (Drosophila)	0.408
Cdh11	cadherin 11	0.407
Shc3	src homology 2 domain-containing transforming protein C3	0.406
Lhx9	LIM homeobox protein 9	0.406	Mouse
Hif3a	hypoxia inducible factor 3, alpha subunit	0.405	Mouse
Dlg1	discs, large homolog 1 (Drosophila)	0.400
Ebf3	early B-cell factor 3	0.400
Plcd1	phospholipase C, delta 1	0.400
Sufu	suppressor of fused homolog (Drosophila)	0.397
Sp1	trans-acting transcription factor 1	0.396
Cacna1s	calcium channel, voltage-dependent, L type, alpha 1S subunit	0.393
Alkbh1	alkB, alkylation repair homolog 1 (E. coli)	0.393
Prph2	peripherin 2	0.393
Plcg1	phospholipase C, gamma 1	0.389
Nab1	Ngfi-A binding protein 1	0.389
Ltbp3	latent transforming growth factor beta binding protein 3	0.387
Plxnd1	plexin D1	0.387	Mouse
Chd7	chromodomain helicase DNA binding protein 7	0.386	Human
Kdm6a	4lysine (K)-specific demethylase 6A	0.386
Eya4	eyes absent 4 homolog (Drosophila)	0.384	Mouse
Gpr182	G protein-coupled receptor 182	0.384
Otx1	orthodenticle homolog 1 (Drosophila)	0.384
Odz2	odd Oz/ten-m homolog 2 (Drosophila)	0.381
Idua	iduronidase, alpha-L-	0.381
Tll1	tolloid-like	0.380
Creb1	cAMP responsive element binding protein 1	0.379
Fras1	Fraser syndrome 1 homolog (human)	0.379	Zebrafish
Hhat	hedgehog acyltransferase	0.378
Htra3	HtrA serine peptidase 3	0.378
Npr2	natriuretic peptide receptor 2	0.378
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.378
5430421N21Rik	RIKEN cDNA 5430421N21 gene	0.376
Cux2	cut-like homeobox 2	0.375
Nfix	nuclear factor I/X	0.375	Mouse
Galr2	galanin receptor 2	0.374
Col6a3	collagen, type VI, alpha 3	0.374
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.373	Mouse
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.372
Zic4	zinc finger protein of the cerebellum 4	0.370
Lep	leptin	0.368
Hoxb7	homeobox B7	0.366
Insm1	insulinoma-associated 1	0.366
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.365
Cbfb	core binding factor beta	0.363
Sox4	SRY-box containing gene 4	0.363
Rest	RE1-silencing transcription factor	0.363
Nkx2-9	NK2 transcription factor related, locus 9 (Drosophila)	0.363	Mouse
Tlr2	toll-like receptor 2	0.363
Chrng	cholinergic receptor, nicotinic, gamma polypeptide	0.362
Adra2c	adrenergic receptor, alpha 2c	0.362
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.362
Cyp1b1	cytochrome P450, family 1, subfamily b, polypeptide 1	0.361
Bmi1	Bmi1 polycomb ring finger oncogene	0.360
Fshr	follicle stimulating hormone receptor	0.360
Lhx6	LIM homeobox protein 6	0.359	Mouse
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.359
Sp3	trans-acting transcription factor 3	0.357
Bhlhe23	basic helix-loop-helix family, member e23	0.357
Smad7	MAD homolog 7 (Drosophila)	0.355	Mouse
Tert	telomerase reverse transcriptase	0.355
Flt1	FMS-like tyrosine kinase 1	0.352	Mouse
Sim2	single-minded homolog 2 (Drosophila)	0.351	Mouse
Nkx2-6	NK2 transcription factor related, locus 6 (Drosophila)	0.349	Mouse
Sema5b	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B	0.348
Irx2	Iroquois related homeobox 2 (Drosophila)	0.348
Hmx2	H6 homeobox 2	0.347
Hoxc5	homeobox C5	0.346
App	amyloid beta (A4) precursor protein	0.346
Plekha4	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4	0.346
Sult5a1	sulfotransferase family 5A, member 1	0.346
Krt72-ps	keratin 72, pseudogene	0.345
Cbl	Casitas B-lineage lymphoma	0.345
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.344
Sstr4	somatostatin receptor 4	0.344
Cldn3	claudin 3	0.343
Cabp2	calcium binding protein 2	0.343
Nppc	natriuretic peptide type C	0.342
Cdkn1c	cyclin-dependent kinase inhibitor 1C (P57)	0.341
Pou4f2	POU domain, class 4, transcription factor 2	0.341
Ntsr1	neurotensin receptor 1	0.340
Itga8	integrin alpha 8	0.338
Ptprn2	protein tyrosine phosphatase, receptor type, N polypeptide 2	0.338
Des	desmin	0.337
Nkx6-1	NK6 homeobox 1	0.336
Ssbp3	single-stranded DNA binding protein 3	0.335
Gfpt2	glutamine fructose-6-phosphate transaminase 2	0.335
Gpr50	G-protein-coupled receptor 50	0.334
Sfn	stratifin	0.333
Lfng	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	0.333
Epx	eosinophil peroxidase	0.333
Ihh	Indian hedgehog	0.333
Prph	peripherin	0.332
Alppl2	alkaline phosphatase, placental-like 2	0.331	Mouse
Wnt9b	wingless-type MMTV integration site 9B	0.331
Hes3	hairy and enhancer of split 3 (Drosophila)	0.330	Mouse
Neurod4	neurogenic differentiation 4	0.330	Mouse
Fkbp10	FK506 binding protein 10	0.330
Tcf15	transcription factor 15	0.328
Col4a2	collagen, type IV, alpha 2	0.327
Cdx1	caudal type homeobox 1	0.326
Isl1	ISL1 transcription factor, LIM/homeodomain	0.324	Mouse
Wls	wntless homolog (Drosophila)	0.323
Maf	avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog	0.323
Rxrg	retinoid X receptor gamma	0.323
3110079O15Rik	RIKEN cDNA 3110079O15 gene	0.321
Psap	prosaposin	0.321
Sulf2	sulfatase 2	0.320
Irx1	Iroquois related homeobox 1 (Drosophila)	0.320
Kera	keratocan	0.319
Ptprd	protein tyrosine phosphatase, receptor type, D	0.319
Tg	thyroglobulin	0.319
Sox14	SRY-box containing gene 14	0.319
Dach1	dachshund 1 (Drosophila)	0.319
Wfikkn1	WAP, FS, Ig, KU, and NTR-containing protein 1	0.319
Sorbs3	sorbin and SH3 domain containing 3	0.318
F2r	coagulation factor II (thrombin) receptor	0.318
Nf2	neurofibromatosis 2	0.318
Hdac4	histone deacetylase 4	0.318
Aebp1	AE binding protein 1	0.317
Ptx3	pentraxin related gene	0.317
Sox5	SRY-box containing gene 5	0.312
BC024139	cDNA sequence BC024139	0.311
Tgfa	transforming growth factor alpha	0.311
Igf1r	insulin-like growth factor I receptor	0.311
Col18a1	collagen, type XVIII, alpha 1	0.309
Amh	anti-Mullerian hormone	0.308
Cdh6	cadherin 6	0.307
Stat1	signal transducer and activator of transcription 1	0.307
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.307	Human Mouse
Mll1	myeloid/lymphoid or mixed-lineage leukemia 1	0.306
Mab21l2	mab-21-like 2 (C. elegans)	0.306
Krt35	keratin 35	0.306
Csf3	colony stimulating factor 3 (granulocyte)	0.304
Barx2	BarH-like homeobox 2	0.303
Timp2	tissue inhibitor of metalloproteinase 2	0.303
Zfhx3	zinc finger homeobox 3	0.303
Oprd1	opioid receptor, delta 1	0.302
Hoxc13	homeobox C13	0.301	Mouse
Wnt8b	wingless related MMTV integration site 8b	0.301	Mouse
Rgnef	Rho-guanine nucleotide exchange factor	0.301
Tagln	transgelin	0.301
Dnase1l2	deoxyribonuclease 1-like 2	0.301
Scara3	scavenger receptor class A, member 3	0.300
Cdkn2d	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	0.300
Clcnka	chloride channel Ka	0.299
Ptprs	protein tyrosine phosphatase, receptor type, S	0.299
Bai1	brain-specific angiogenesis inhibitor 1	0.299
Ephb4	Eph receptor B4	0.298	Mouse
Tlx1	T-cell leukemia, homeobox 1	0.297
Hoxd4	homeobox D4	0.297
Mnx1	motor neuron and pancreas homeobox 1	0.296
Gab1	growth factor receptor bound protein 2-associated protein 1	0.295
Hoxa7	homeobox A7	0.295
Dbx1	developing brain homeobox 1	0.294	Mouse
Tgfbr1	transforming growth factor, beta receptor I	0.294
Wwtr1	WW domain containing transcription regulator 1	0.294
Zbtb16	zinc finger and BTB domain containing 16	0.293
Fst	follistatin	0.290
Acvr2a	activin receptor IIA	0.290
Odz4	odd Oz/ten-m homolog 4 (Drosophila)	0.290
Nanog	Nanog homeobox	0.289
E130012A19Rik	RIKEN cDNA E130012A19 gene	0.289
Slc27a3	solute carrier family 27 (fatty acid transporter), member 3	0.288
Rxra	retinoid X receptor alpha	0.288
Col8a1	collagen, type VIII, alpha 1	0.287
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.287
Pvrl1	poliovirus receptor-related 1	0.286
Robo2	roundabout homolog 2 (Drosophila)	0.285
Foxb1	forkhead box B1	0.284
Rs1	retinoschisis (X-linked, juvenile) 1 (human)	0.282
Dmrt3	doublesex and mab-3 related transcription factor 3	0.282	Mouse
Bcl11b	B-cell leukemia/lymphoma 11B	0.281
Fosl2	fos-like antigen 2	0.279
Hoxb13	homeobox B13	0.279	Mouse
Fmod	fibromodulin	0.278
Socs1	suppressor of cytokine signaling 1	0.278
Sstr1	somatostatin receptor 1	0.278
Epha5	Eph receptor A5	0.277	Mouse
Fam114a1	family with sequence similarity 114, member A1	0.277
Nf1	neurofibromatosis 1	0.277
Mecom	MDS1 and EVI1 complex locus	0.276	Zebrafish
Trp63	transformation related protein 63	0.276
Ptpru	protein tyrosine phosphatase, receptor type, U	0.275
Lrp4	low density lipoprotein receptor-related protein 4	0.275	Mouse
Pou3f4	POU domain, class 3, transcription factor 4	0.274
Vipr1	vasoactive intestinal peptide receptor 1	0.274	Mouse
Tcl1	T-cell lymphoma breakpoint 1	0.272
Clcn2	chloride channel 2	0.271
Ggt1	gamma-glutamyltransferase 1	0.271
Hes2	hairy and enhancer of split 2 (Drosophila)	0.271	Mouse
Irx3	Iroquois related homeobox 3 (Drosophila)	0.270
Cdh1	cadherin 1	0.269
Zfhx4	zinc finger homeodomain 4	0.269
Pkdcc	protein kinase domain containing, cytoplasmic	0.269
Adam12	a disintegrin and metallopeptidase domain 12 (meltrin alpha)	0.269
Upk3b	uroplakin 3B	0.269
Bbs2	Bardet-Biedl syndrome 2 (human)	0.268
Kdm5a	lysine (K)-specific demethylase 5A	0.268
Hs6st3	heparan sulfate 6-O-sulfotransferase 3	0.267
Agap3	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3	0.266
Cachd1	cache domain containing 1	0.266
Scarf2	scavenger receptor class F, member 2	0.266
Krtap3-3	keratin associated protein 3-3	0.266
Smtn	smoothelin	0.266
Onecut1	one cut domain, family member 1	0.265
Ccdc80	coiled-coil domain containing 80	0.265
Tcf4	transcription factor 4	0.264
Mgat3	mannoside acetylglucosaminyltransferase 3	0.264
Edar	ectodysplasin-A receptor	0.264
Tecta	tectorin alpha	0.263
Mfap4	microfibrillar-associated protein 4	0.263
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.262
Id4	inhibitor of DNA binding 4	0.262
Slc8a2	solute carrier family 8 (sodium/calcium exchanger), member 2	0.262
Nod2	nucleotide-binding oligomerization domain containing 2	0.261
Sox21	SRY-box containing gene 21	0.260
Nrtn	neurturin	0.259
Ldb3	LIM domain binding 3	0.259
Cacnb3	calcium channel, voltage-dependent, beta 3 subunit	0.258
Tcf7	transcription factor 7, T-cell specific	0.258
Mertk	c-mer proto-oncogene tyrosine kinase	0.257	Mouse
Plekha1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	0.257
Padi3	peptidyl arginine deiminase, type III	0.257
Cbfa2t3	core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)	0.257
Ext1	exostoses (multiple) 1	0.256
Irs2	insulin receptor substrate 2	0.256
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.256	Mouse
Numb	numb gene homolog (Drosophila)	0.255
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.255
Crh	corticotropin releasing hormone	0.255
Irs1	insulin receptor substrate 1	0.254
Daxx	Fas death domain-associated protein	0.253
Foxa3	forkhead box A3	0.252	Mouse
Rhbdl3	rhomboid, veinlet-like 3 (Drosophila)	0.252
Sp8	trans-acting transcription factor 8	0.251	Mouse
Mafb	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.250	Mouse
Slc4a8	solute carrier family 4 (anion exchanger), member 8	0.250
Ldb1	LIM domain binding 1	0.250
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.250
Cdh13	cadherin 13	0.250
Sin3a	transcriptional regulator, SIN3A (yeast)	0.249
Bbs1	Bardet-Biedl syndrome 1 (human)	0.249
Src	Rous sarcoma oncogene	0.249
Rtkn	rhotekin	0.248
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.247
Ptms	parathymosin	0.246
Pias1	protein inhibitor of activated STAT 1	0.245
Hs3st3b1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1	0.244
Rcvrn	recoverin	0.242
Wnt9a	wingless-type MMTV integration site 9A	0.241
Bmf	BCL2 modifying factor	0.240
Mapk3	mitogen-activated protein kinase 3	0.240
Tsc2	tuberous sclerosis 2	0.239
Fn1	fibronectin 1	0.238	Zebrafish
Sox13	SRY-box containing gene 13	0.238	Mouse
Nmu	neuromedin U	0.238
Bach1	BTB and CNC homology 1	0.237
Myf6	myogenic factor 6	0.237	Mouse
Gabra2	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2	0.237
Fbxw7	F-box and WD-40 domain protein 7	0.237
Lhx4	LIM homeobox protein 4	0.236	Mouse
Ikbkg	inhibitor of kappaB kinase gamma	0.236
Apba2	amyloid beta (A4) precursor protein-binding, family A, member 2	0.236
Bmp6	bone morphogenetic protein 6	0.235
Fgf23	fibroblast growth factor 23	0.234
Itgav	integrin alpha V	0.234
Rac1	RAS-related C3 botulinum substrate 1	0.234
Bfsp1	beaded filament structural protein 1, in lens-CP94	0.233
Pcgf2	polycomb group ring finger 2	0.232
Cdh15	cadherin 15	0.232
Ctdsp2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2	0.232
Dmpk	dystrophia myotonica-protein kinase	0.231
Phlda2	pleckstrin homology-like domain, family A, member 2	0.230
Foxj1	forkhead box J1	0.230
Ctsk	cathepsin K	0.229
Rln1	relaxin 1	0.228
Tmem119	transmembrane protein 119	0.228
F2	coagulation factor II	0.228
Cpn1	carboxypeptidase N, polypeptide 1	0.227
Nobox	NOBOX oogenesis homeobox	0.226
Thrb	thyroid hormone receptor beta	0.226	Mouse Rat
Inpp5d	inositol polyphosphate-5-phosphatase D	0.226
Foxl1	forkhead box L1	0.226
Adamts2	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2	0.226
Col9a2	collagen, type IX, alpha 2	0.225
Slc5a11	solute carrier family 5 (sodium/glucose cotransporter), member 11	0.225
Igfbp4	insulin-like growth factor binding protein 4	0.224
Sp7	Sp7 transcription factor 7	0.224
Omp	olfactory marker protein	0.224
Terf1	telomeric repeat binding factor 1	0.222
Celsr1	cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)	0.222
Tmem45a	transmembrane protein 45a	0.222
Zfp36l1	zinc finger protein 36, C3H type-like 1	0.221
Zp3	zona pellucida glycoprotein 3	0.221
Kcns1	K+ voltage-gated channel, subfamily S, 1	0.220
Dmrtb1	DMRT-like family B with proline-rich C-terminal, 1	0.220