IMP: Integrative Multi-species Prediction

Mus musculus

3 genes annotated in mouse

Multi-species View

positive regulation of t helper 2 cell cytokine production

GO:2000553

Any process that activates or increases the frequency, rate or extent of T-helper 2 cell cytokine production.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of t helper 2 cell cytokine production"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "positive regulation of t helper 2 cell cytokine production" (in gray)

Name	Description	Probability	Func Analog Organism
Ccl8	chemokine (C-C motif) ligand 8	0.961
Ccl2	chemokine (C-C motif) ligand 2	0.960
Cxcl2	chemokine (C-X-C motif) ligand 2	0.851
Ccl12	chemokine (C-C motif) ligand 12	0.795	Mouse
Ccl4	chemokine (C-C motif) ligand 4	0.684	Mouse
Ccl3	chemokine (C-C motif) ligand 3	0.644	Mouse
Ch25h	cholesterol 25-hydroxylase	0.638
Ccr1	chemokine (C-C motif) receptor 1	0.571
Cxcl9	chemokine (C-X-C motif) ligand 9	0.570
Akt1	thymoma viral proto-oncogene 1	0.555	Mouse
Vhl	von Hippel-Lindau tumor suppressor	0.551
Il1b	interleukin 1 beta	0.534
Mmp12	matrix metallopeptidase 12	0.527
Gzma	granzyme A	0.448
Cd3e	CD3 antigen, epsilon polypeptide	0.423
Ldb3	LIM domain binding 3	0.416
Cd40	CD40 antigen	0.405
Folr2	folate receptor 2 (fetal)	0.381
Ccl9	chemokine (C-C motif) ligand 9	0.376	Mouse
C3ar1	complement component 3a receptor 1	0.374
Fcgr1	Fc receptor, IgG, high affinity I	0.373
Gzmb	granzyme B	0.342
Ubd	ubiquitin D	0.315
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.310
Ccl22	chemokine (C-C motif) ligand 22	0.299
Ccl7	chemokine (C-C motif) ligand 7	0.284	Mouse
Irg1	immunoresponsive gene 1	0.266
Gdf15	growth differentiation factor 15	0.255
Tnf	tumor necrosis factor	0.238
Itgax	integrin alpha X	0.221
Clec4d	C-type lectin domain family 4, member d	0.208
Msr1	macrophage scavenger receptor 1	0.201
Slamf8	SLAM family member 8	0.197
Cd7	CD7 antigen	0.187
Ctsw	cathepsin W	0.187
Ccr2	chemokine (C-C motif) receptor 2	0.186
Irf7	interferon regulatory factor 7	0.184
Il1rn	interleukin 1 receptor antagonist	0.179
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.175
Batf2	basic leucine zipper transcription factor, ATF-like 2	0.172
Cxcl10	chemokine (C-X-C motif) ligand 10	0.169
Xcl1	chemokine (C motif) ligand 1	0.160
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.157
Ifit1	interferon-induced protein with tetratricopeptide repeats 1	0.137
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.132
Batf	basic leucine zipper transcription factor, ATF-like	0.122
Ncr1	natural cytotoxicity triggering receptor 1	0.112
Ccl17	chemokine (C-C motif) ligand 17	0.103	Mouse
Cxcl1	chemokine (C-X-C motif) ligand 1	0.098
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.097
Ifng	interferon gamma	0.097
Sh2d2a	SH2 domain protein 2A	0.096
Ccr5	chemokine (C-C motif) receptor 5	0.094
Saa3	serum amyloid A 3	0.094
Icos	inducible T-cell co-stimulator	0.091
Socs1	suppressor of cytokine signaling 1	0.090
Lag3	lymphocyte-activation gene 3	0.089
Ccl5	chemokine (C-C motif) ligand 5	0.086	Mouse
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.074
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.073
Akt2	thymoma viral proto-oncogene 2	0.072	Mouse
Rasal1	RAS protein activator like 1 (GAP1 like)	0.072
Pdcd1	programmed cell death 1	0.071
Il6	interleukin 6	0.071
Mmp13	matrix metallopeptidase 13	0.068
Csnk1g2	casein kinase 1, gamma 2	0.066
Tnfrsf18	tumor necrosis factor receptor superfamily, member 18	0.064
Gm11428	predicted gene 11428	0.063
AF251705	cDNA sequence AF251705	0.063
Cd14	CD14 antigen	0.063
Ly9	lymphocyte antigen 9	0.060
Cd86	CD86 antigen	0.060
Mx2	myxovirus (influenza virus) resistance 2	0.060
H2-Aa	histocompatibility 2, class II antigen A, alpha	0.060
C1qc	complement component 1, q subcomponent, C chain	0.059
Nkg7	natural killer cell group 7 sequence	0.056
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.056
Fasl	Fas ligand (TNF superfamily, member 6)	0.056
Il2rb	interleukin 2 receptor, beta chain	0.056
Mmp3	matrix metallopeptidase 3	0.055
Cd8a	CD8 antigen, alpha chain	0.054
Scn1b	sodium channel, voltage-gated, type I, beta	0.053
Ltc4s	leukotriene C4 synthase	0.052
H2-Eb1	histocompatibility 2, class II antigen E beta	0.052
Selp	selectin, platelet	0.049
C1qb	complement component 1, q subcomponent, beta polypeptide	0.049
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.047
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.045
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.044
Cma1	chymase 1, mast cell	0.043
Mlf2	myeloid leukemia factor 2	0.043
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.043
Prkce	protein kinase C, epsilon	0.042
Gfpt2	glutamine fructose-6-phosphate transaminase 2	0.042
C1qa	complement component 1, q subcomponent, alpha polypeptide	0.042
Lilrb3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.041
Pdcd1lg2	programmed cell death 1 ligand 2	0.041
Aoah	acyloxyacyl hydrolase	0.040
Ccl6	chemokine (C-C motif) ligand 6	0.040	Mouse
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.040
Slamf9	SLAM family member 9	0.039
Hcst	hematopoietic cell signal transducer	0.039
Oasl1	2'-5' oligoadenylate synthetase-like 1	0.039
Mapkap1	mitogen-activated protein kinase associated protein 1	0.038
Cd96	CD96 antigen	0.038
Cxcl13	chemokine (C-X-C motif) ligand 13	0.038
Ly6i	lymphocyte antigen 6 complex, locus I	0.038
Ccrl2	chemokine (C-C motif) receptor-like 2	0.037
Cxcl16	chemokine (C-X-C motif) ligand 16	0.037
Actn2	actinin alpha 2	0.037
Slc39a7	solute carrier family 39 (zinc transporter), member 7	0.036
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.036
Il1a	interleukin 1 alpha	0.035
Il18rap	interleukin 18 receptor accessory protein	0.035
AW112010	expressed sequence AW112010	0.035
Klrb1c	killer cell lectin-like receptor subfamily B member 1C	0.034
Serpina3g	serine (or cysteine) peptidase inhibitor, clade A, member 3G	0.034
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.033
Slamf7	SLAM family member 7	0.033
Retnla	resistin like alpha	0.033
Lta	lymphotoxin A	0.032
Cst7	cystatin F (leukocystatin)	0.032
Ccr7	chemokine (C-C motif) receptor 7	0.032
Tbxas1	thromboxane A synthase 1, platelet	0.032
Mapkapk2	MAP kinase-activated protein kinase 2	0.032
Pparg	peroxisome proliferator activated receptor gamma	0.032
Ms4a6d	membrane-spanning 4-domains, subfamily A, member 6D	0.031
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.031
Ccl24	chemokine (C-C motif) ligand 24	0.031	Mouse
Cd3d	CD3 antigen, delta polypeptide	0.030
Mpeg1	macrophage expressed gene 1	0.030
AI607873	expressed sequence AI607873	0.030
Cd28	CD28 antigen	0.030
Fcna	ficolin A	0.029
Apod	apolipoprotein D	0.029
Sele	selectin, endothelial cell	0.029
Hp	haptoglobin	0.029
Ms4a6c	membrane-spanning 4-domains, subfamily A, member 6C	0.029
Clec4n	C-type lectin domain family 4, member n	0.029
Bcl2a1d	B-cell leukemia/lymphoma 2 related protein A1d	0.029
Atf3	activating transcription factor 3	0.029
Il18r1	interleukin 18 receptor 1	0.029
Selplg	selectin, platelet (p-selectin) ligand	0.028
Niacr1	niacin receptor 1	0.028
Cfb	complement factor B	0.028
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.028
Nnmt	nicotinamide N-methyltransferase	0.027
Stat4	signal transducer and activator of transcription 4	0.027
Has1	hyaluronan synthase1	0.027
Tlr7	toll-like receptor 7	0.027
Ccl11	chemokine (C-C motif) ligand 11	0.027	Mouse
Gzmc	granzyme C	0.027
Lep	leptin	0.027
Rgs1	regulator of G-protein signaling 1	0.026
H2-Ab1	histocompatibility 2, class II antigen A, beta 1	0.026
Cish	cytokine inducible SH2-containing protein	0.026
Bcl2	B-cell leukemia/lymphoma 2	0.025
Cdk14	cyclin-dependent kinase 14	0.025
Tbx21	T-box 21	0.025
Ehmt2	euchromatic histone lysine N-methyltransferase 2	0.025
Nphs2	nephrosis 2 homolog, podocin (human)	0.024
Il1rl1	interleukin 1 receptor-like 1	0.024
Ms4a7	membrane-spanning 4-domains, subfamily A, member 7	0.024
Kctd20	potassium channel tetramerisation domain containing 20	0.024
F10	coagulation factor X	0.023
Ilk	integrin linked kinase	0.023
Ctdnep1	CTD nuclear envelope phosphatase 1	0.023
Csf1	colony stimulating factor 1 (macrophage)	0.023
Fxyd2	FXYD domain-containing ion transport regulator 2	0.022
Clec4e	C-type lectin domain family 4, member e	0.022
Oas3	2'-5' oligoadenylate synthetase 3	0.022
Cp	ceruloplasmin	0.022
Jak3	Janus kinase 3	0.021
Chad	chondroadherin	0.021
Cd3g	CD3 antigen, gamma polypeptide	0.021
Mthfs	5, 10-methenyltetrahydrofolate synthetase	0.021
Zbp1	Z-DNA binding protein 1	0.021
Ifitm6	interferon induced transmembrane protein 6	0.021
Gm12185	predicted gene 12185	0.021
Scrg1	scrapie responsive gene 1	0.021
Oas2	2'-5' oligoadenylate synthetase 2	0.021
Agap3	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3	0.021
Cfp	complement factor properdin	0.020
Tnfsf10	tumor necrosis factor (ligand) superfamily, member 10	0.020
Wdr1	WD repeat domain 1	0.020
Expi	extracellular proteinase inhibitor	0.020
Hba-a2	hemoglobin alpha, adult chain 2	0.020
Aif1	allograft inflammatory factor 1	0.020
Gpr84	G protein-coupled receptor 84	0.019
Ifit3	interferon-induced protein with tetratricopeptide repeats 3	0.019
Cd74	CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)	0.019
Clec7a	C-type lectin domain family 7, member a	0.019
Stub1	STIP1 homology and U-Box containing protein 1	0.019
Prkca	protein kinase C, alpha	0.019
Nudt3	nudix (nucleotide diphosphate linked moiety X)-type motif 3	0.019
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.019
Slfn2	schlafen 2	0.019
Clec5a	C-type lectin domain family 5, member a	0.019
Tyrobp	TYRO protein tyrosine kinase binding protein	0.019
Junb	Jun-B oncogene	0.018
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.018
Tnfaip2	tumor necrosis factor, alpha-induced protein 2	0.018
Igf1r	insulin-like growth factor I receptor	0.018
Gpr133	G protein-coupled receptor 133	0.018
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.018
Gzmk	granzyme K	0.018
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.018
Mrc1	mannose receptor, C type 1	0.018
Ms4a8a	membrane-spanning 4-domains, subfamily A, member 8A	0.017
Adora2b	adenosine A2b receptor	0.017
Git1	G protein-coupled receptor kinase-interactor 1	0.017
Slpi	secretory leukocyte peptidase inhibitor	0.017
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.017
Dab2	disabled homolog 2 (Drosophila)	0.017
Traf1	TNF receptor-associated factor 1	0.017
Psmd3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	0.017
Cxcl5	chemokine (C-X-C motif) ligand 5	0.017
Ube2l6	ubiquitin-conjugating enzyme E2L 6	0.017
Mxd1	MAX dimerization protein 1	0.017
Ly6c2	lymphocyte antigen 6 complex, locus C2	0.016
Drap1	Dr1 associated protein 1 (negative cofactor 2 alpha)	0.016
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.016
Lrg1	leucine-rich alpha-2-glycoprotein 1	0.016
Fcrls	Fc receptor-like S, scavenger receptor	0.016
Bcl3	B-cell leukemia/lymphoma 3	0.016
Iigp1	interferon inducible GTPase 1	0.016
Steap4	STEAP family member 4	0.016
Add1	adducin 1 (alpha)	0.016
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.016
Siglece	sialic acid binding Ig-like lectin E	0.016
Ear11	eosinophil-associated, ribonuclease A family, member 11	0.016
Slfn1	schlafen 1	0.016
Il12rb1	interleukin 12 receptor, beta 1	0.016
Ccl19	chemokine (C-C motif) ligand 19	0.016	Mouse
Mnda	myeloid cell nuclear differentiation antigen	0.015
Il18bp	interleukin 18 binding protein	0.015
Ache	acetylcholinesterase	0.015
Ccl20	chemokine (C-C motif) ligand 20	0.015
Pf4	platelet factor 4	0.015
Cd151	CD151 antigen	0.015
Aamp	angio-associated migratory protein	0.015
C2	complement component 2 (within H-2S)	0.015
Lgals3	lectin, galactose binding, soluble 3	0.015
Alox15	arachidonate 15-lipoxygenase	0.015
Trim35	tripartite motif-containing 35	0.015
Scg3	secretogranin III	0.015
Phlpp1	PH domain and leucine rich repeat protein phosphatase 1	0.015
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.014
Ltk	leukocyte tyrosine kinase	0.014
C5ar1	complement component 5a receptor 1	0.014
Lyve1	lymphatic vessel endothelial hyaluronan receptor 1	0.014
Cd6	CD6 antigen	0.014
Cd163	CD163 antigen	0.014
Blnk	B-cell linker	0.014
Pde1b	phosphodiesterase 1B, Ca2+-calmodulin dependent	0.014
Il10ra	interleukin 10 receptor, alpha	0.014
Fastk	Fas-activated serine/threonine kinase	0.014
Socs3	suppressor of cytokine signaling 3	0.014
Ninj1	ninjurin 1	0.014
Dctn1	dynactin 1	0.014
Fpr2	formyl peptide receptor 2	0.014
Pla1a	phospholipase A1 member A	0.014
Tomm40	translocase of outer mitochondrial membrane 40 homolog (yeast)	0.013
Fcgr3	Fc receptor, IgG, low affinity III	0.013
Cd300ld	CD300 molecule-like family member d	0.013
Vcam1	vascular cell adhesion molecule 1	0.013
Cd36	CD36 antigen	0.013
Sytl3	synaptotagmin-like 3	0.013
Galnt2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2	0.013
Fcgr4	Fc receptor, IgG, low affinity IV	0.013
Rgs16	regulator of G-protein signaling 16	0.013
F13a1	coagulation factor XIII, A1 subunit	0.013
Ly6a	lymphocyte antigen 6 complex, locus A	0.013
Serpinb9b	serine (or cysteine) peptidase inhibitor, clade B, member 9b	0.013
Cd8b1	CD8 antigen, beta chain 1	0.013
Gsk3b	glycogen synthase kinase 3 beta	0.013
Clcn1	chloride channel 1	0.013
Nr4a3	nuclear receptor subfamily 4, group A, member 3	0.013
Fpr1	formyl peptide receptor 1	0.013
Actn4	actinin alpha 4	0.013
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.013
Osmr	oncostatin M receptor	0.013
Arc	activity regulated cytoskeletal-associated protein	0.012
Trim46	tripartite motif-containing 46	0.012
Nek6	NIMA (never in mitosis gene a)-related expressed kinase 6	0.012
Gpr35	G protein-coupled receptor 35	0.012
Gng4	guanine nucleotide binding protein (G protein), gamma 4	0.012
Agap2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	0.012
Gnb2	guanine nucleotide binding protein (G protein), beta 2	0.012
Fxyd7	FXYD domain-containing ion transport regulator 7	0.012
Fosl1	fos-like antigen 1	0.012
Il1r2	interleukin 1 receptor, type II	0.012
Mbd3	methyl-CpG binding domain protein 3	0.012
Pvalb	parvalbumin	0.012
Lcn2	lipocalin 2	0.012
Clec4a2	C-type lectin domain family 4, member a2	0.012
Plcb1	phospholipase C, beta 1	0.012
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.012
Csf3	colony stimulating factor 3 (granulocyte)	0.011
Timp1	tissue inhibitor of metalloproteinase 1	0.011
Ppp5c	protein phosphatase 5, catalytic subunit	0.011
Klc1	kinesin light chain 1	0.011
Cd160	CD160 antigen	0.011
Prkar1b	protein kinase, cAMP dependent regulatory, type I beta	0.011
Traf6	TNF receptor-associated factor 6	0.011
Bag6	BCL2-associated athanogene 6	0.011
Cpne6	copine VI	0.011
Cd27	CD27 antigen	0.011
Tg	thyroglobulin	0.011
Cd244	CD244 natural killer cell receptor 2B4	0.011
Icam1	intercellular adhesion molecule 1	0.011
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.011
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.011
Pdpn	podoplanin	0.011
Rab3il1	RAB3A interacting protein (rabin3)-like 1	0.011
Plekho2	pleckstrin homology domain containing, family O member 2	0.011
Irf4	interferon regulatory factor 4	0.011
Slfn3	schlafen 3	0.011
Snx20	sorting nexin 20	0.011
Hck	hemopoietic cell kinase	0.011
Creb1	cAMP responsive element binding protein 1	0.011
Ptov1	prostate tumor over expressed gene 1	0.011
Plp1	proteolipid protein (myelin) 1	0.011
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.011
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.011
Homer1	homer homolog 1 (Drosophila)	0.010
Egln1	EGL nine homolog 1 (C. elegans)	0.010
C4b	complement component 4B (Childo blood group)	0.010
Fcamr	Fc receptor, IgA, IgM, high affinity	0.010
S100a4	S100 calcium binding protein A4	0.010
Lyz1	lysozyme 1	0.010
Gna12	guanine nucleotide binding protein, alpha 12	0.010
Mcoln2	mucolipin 2	0.010
Ncln	nicalin homolog (zebrafish)	0.010
Cxcr3	chemokine (C-X-C motif) receptor 3	0.010
Apoc2	apolipoprotein C-II	0.010
Cd33	CD33 antigen	0.010
Il2	interleukin 2	0.010
Isg20	interferon-stimulated protein	0.010
Ramp3	receptor (calcitonin) activity modifying protein 3	0.010
Btbd10	BTB (POZ) domain containing 10	0.010
Krtap3-1	keratin associated protein 3-1	0.010