IMP: Integrative Multi-species Prediction

Mus musculus

112 genes annotated in mouse

regulation of transmembrane receptor protein serine threonine kinase signaling pathway

Any process that modulates the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of transmembrane receptor protein serine threonine kinase signaling pathway"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "regulation of transmembrane receptor protein serine threonine kinase signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
Tgfb2	transforming growth factor, beta 2	0.998	Fly
Pitx2	paired-like homeodomain transcription factor 2	0.987
Bmp4	bone morphogenetic protein 4	0.979
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.977
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.977	Mouse
Smad6	MAD homolog 6 (Drosophila)	0.966	Human Mouse Fly
Fgfr2	fibroblast growth factor receptor 2	0.966
Acvr1	activin A receptor, type 1	0.966	Human Mouse Fly
Nodal	nodal	0.958	Mouse
Shh	sonic hedgehog	0.956	Zebrafish
Chrd	chordin	0.949
Otx2	orthodenticle homolog 2 (Drosophila)	0.940
Smad7	MAD homolog 7 (Drosophila)	0.915
Smad3	MAD homolog 3 (Drosophila)	0.915
Vegfa	vascular endothelial growth factor A	0.877
Hoxa1	homeobox A1	0.877
Lef1	lymphoid enhancer binding factor 1	0.854	Mouse
Fgf8	fibroblast growth factor 8	0.843
Gli3	GLI-Kruppel family member GLI3	0.842
Tcfap2a	transcription factor AP-2, alpha	0.824	Mouse
Alx4	aristaless-like homeobox 4	0.821
Nog	noggin	0.811
Sox2	SRY-box containing gene 2	0.810	Mouse
Tbx3	T-box 3	0.789	Mouse
Sfrp2	secreted frizzled-related protein 2	0.767
Gdnf	glial cell line derived neurotrophic factor	0.759
Prrx2	paired related homeobox 2	0.758
Msx2	homeobox, msh-like 2	0.755
Hes1	hairy and enhancer of split 1 (Drosophila)	0.755
Wnt3a	wingless-related MMTV integration site 3A	0.750	Mouse
Apc	adenomatosis polyposis coli	0.747
Snai1	snail homolog 1 (Drosophila)	0.740
Efnb2	ephrin B2	0.737
Tgfbr2	transforming growth factor, beta receptor II	0.724	Mouse
Fgfr1	fibroblast growth factor receptor 1	0.720
Amhr2	anti-Mullerian hormone type 2 receptor	0.713	Mouse
Gata4	GATA binding protein 4	0.705
Bmp7	bone morphogenetic protein 7	0.702	Human Mouse
Axin1	axin 1	0.697
Rarb	retinoic acid receptor, beta	0.670
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.661	Human
Prrx1	paired related homeobox 1	0.656
Pax3	paired box gene 3	0.647
Foxa2	forkhead box A2	0.644	Mouse
Fst	follistatin	0.639	Human Mouse
Pten	phosphatase and tensin homolog	0.627
Pou5f1	POU domain, class 5, transcription factor 1	0.610	Human
Gata6	GATA binding protein 6	0.589
Smad4	MAD homolog 4 (Drosophila)	0.584
Eng	endoglin	0.583	Human
Fgf5	fibroblast growth factor 5	0.561	Mouse
Tbx1	T-box 1	0.555	Mouse
Gpc3	glypican 3	0.553
Eya1	eyes absent 1 homolog (Drosophila)	0.550
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.547
Onecut1	one cut domain, family member 1	0.537
Kdr	kinase insert domain protein receptor	0.536
Hand1	heart and neural crest derivatives expressed transcript 1	0.533
Foxh1	forkhead box H1	0.525	Zebrafish
Grb10	growth factor receptor bound protein 10	0.520
Fgf15	fibroblast growth factor 15	0.514
Ntn1	netrin 1	0.511
Twist2	twist homolog 2 (Drosophila)	0.509
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.507
Fzd1	frizzled homolog 1 (Drosophila)	0.507
Zic3	zinc finger protein of the cerebellum 3	0.506
Mapk14	mitogen-activated protein kinase 14	0.502	Fly
Wnt5a	wingless-related MMTV integration site 5A	0.500
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.485
Inhbb	inhibin beta-B	0.483
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.480
Ptrf	polymerase I and transcript release factor	0.477
Gdf1	growth differentiation factor 1	0.473	Mouse
Trp63	transformation related protein 63	0.469	Mouse
Axin2	axin2	0.466	Mouse
Pou3f3	POU domain, class 3, transcription factor 3	0.466
Ret	ret proto-oncogene	0.465
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.458
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.457	Mouse
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.455
Nkx2-1	NK2 homeobox 1	0.443	Human
Tbx2	T-box 2	0.438	Mouse
Eda	ectodysplasin-A	0.438
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.432	Mouse
Ctnnb1	catenin (cadherin associated protein), beta 1	0.428
Braf	Braf transforming gene	0.428
Gas1	growth arrest specific 1	0.424
Ece1	endothelin converting enzyme 1	0.424
En1	engrailed 1	0.423
Hoxd11	homeobox D11	0.420
Acvrl1	activin A receptor, type II-like 1	0.416
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.414
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.396
Meox2	mesenchyme homeobox 2	0.396
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.393
Sox18	SRY-box containing gene 18	0.392	Mouse
Dlx5	distal-less homeobox 5	0.392
Wnt3	wingless-related MMTV integration site 3	0.392	Mouse
Thbs1	thrombospondin 1	0.371
Smo	smoothened homolog (Drosophila)	0.370
Bcl2	B-cell leukemia/lymphoma 2	0.363
Epas1	endothelial PAS domain protein 1	0.363
Crlf1	cytokine receptor-like factor 1	0.363
Nos3	nitric oxide synthase 3, endothelial cell	0.360
Hand2	heart and neural crest derivatives expressed transcript 2	0.359
Twist1	twist homolog 1 (Drosophila)	0.358
Sox9	SRY-box containing gene 9	0.354	Mouse
Edar	ectodysplasin-A receptor	0.353
Gli2	GLI-Kruppel family member GLI2	0.350
Dll4	delta-like 4 (Drosophila)	0.344
Pax9	paired box gene 9	0.336
Acvr2a	activin receptor IIA	0.335
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.334
Notch1	Notch gene homolog 1 (Drosophila)	0.333
Pax6	paired box gene 6	0.328
Foxc1	forkhead box C1	0.327	Mouse
Gdf3	growth differentiation factor 3	0.325	Mouse
Nf1	neurofibromatosis 1	0.320
Utf1	undifferentiated embryonic cell transcription factor 1	0.320
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.313	Mouse
Ptk7	PTK7 protein tyrosine kinase 7	0.312
Uncx	UNC homeobox	0.312
Jag1	jagged 1	0.307
Sox4	SRY-box containing gene 4	0.301	Mouse
Dlg1	discs, large homolog 1 (Drosophila)	0.299
Ptf1a	pancreas specific transcription factor, 1a	0.299
Sfrp1	secreted frizzled-related protein 1	0.298
Ptgs2	prostaglandin-endoperoxide synthase 2	0.294
Foxc2	forkhead box C2	0.292	Mouse
Atoh7	atonal homolog 7 (Drosophila)	0.291
Tgfbr3	transforming growth factor, beta receptor III	0.291	Rat
Sox7	SRY-box containing gene 7	0.287	Mouse
Adam17	a disintegrin and metallopeptidase domain 17	0.282
Mn1	meningioma 1	0.279
Bmp2	bone morphogenetic protein 2	0.279	Human Mouse
Tcl1	T-cell lymphoma breakpoint 1	0.278
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.274
Sall1	sal-like 1 (Drosophila)	0.272
Gab2	growth factor receptor bound protein 2-associated protein 2	0.270
Wnt11	wingless-related MMTV integration site 11	0.269	Mouse
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.268
Tgfbr1	transforming growth factor, beta receptor I	0.267	Human Mouse Fly
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.266
Hoxd13	homeobox D13	0.266	Mouse
Lrp2	low density lipoprotein receptor-related protein 2	0.265
Cdx2	caudal type homeobox 2	0.262
Gipc3	GIPC PDZ domain containing family, member 3	0.254	Mouse
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.253	Human Mouse
Sema3b	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	0.251
Sall4	sal-like 4 (Drosophila)	0.251
Hoxd9	homeobox D9	0.246
Mgat3	mannoside acetylglucosaminyltransferase 3	0.245
Igf2	insulin-like growth factor 2	0.244
Tgfa	transforming growth factor alpha	0.243
Lama5	laminin, alpha 5	0.242
Csf1	colony stimulating factor 1 (macrophage)	0.235
Itgb3	integrin beta 3	0.235
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.234
Col4a2	collagen, type IV, alpha 2	0.234
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.233
Crebbp	CREB binding protein	0.233
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.231	Mouse
Hic1	hypermethylated in cancer 1	0.230
Inhba	inhibin beta-A	0.228	Human
Acvr2b	activin receptor IIB	0.223	Human Mouse
Smad1	MAD homolog 1 (Drosophila)	0.223	Mouse
Yap1	yes-associated protein 1	0.223
Hif1a	hypoxia inducible factor 1, alpha subunit	0.222
Timp2	tissue inhibitor of metalloproteinase 2	0.220
Flt4	FMS-like tyrosine kinase 4	0.219	Mouse
Bmp5	bone morphogenetic protein 5	0.219	Human Mouse
Ahr	aryl-hydrocarbon receptor	0.219
Nos1	nitric oxide synthase 1, neuronal	0.218
Wnt4	wingless-related MMTV integration site 4	0.215	Mouse
Adam19	a disintegrin and metallopeptidase domain 19 (meltrin beta)	0.214	Mouse
Fbln1	fibulin 1	0.214
Nkx3-1	NK-3 transcription factor, locus 1 (Drosophila)	0.208
Eln	elastin	0.208
Atf2	activating transcription factor 2	0.207
Sox3	SRY-box containing gene 3	0.207	Mouse
Gdf5	growth differentiation factor 5	0.207	Mouse
Ctsk	cathepsin K	0.203
Plcg1	phospholipase C, gamma 1	0.203
Ednrb	endothelin receptor type B	0.202
Cd151	CD151 antigen	0.199
Lep	leptin	0.197
Cdh5	cadherin 5	0.196
Hoxa13	homeobox A13	0.193
Ar	androgen receptor	0.193
Fzd8	frizzled homolog 8 (Drosophila)	0.190	Mouse
Smad5	MAD homolog 5 (Drosophila)	0.189	Zebrafish Mouse
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.186
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.184
Foxf1a	forkhead box F1a	0.183
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.182	Mouse
Rspo1	R-spondin homolog (Xenopus laevis)	0.181
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.181
Col4a1	collagen, type IV, alpha 1	0.181
Nkx2-4	NK2 transcription factor related, locus 4 (Drosophila)	0.180
Lmx1b	LIM homeobox transcription factor 1 beta	0.180
Runx2	runt related transcription factor 2	0.179
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.177
Efs	embryonal Fyn-associated substrate	0.175
Tlx3	T-cell leukemia, homeobox 3	0.175
Gopc	golgi associated PDZ and coiled-coil motif containing	0.175
Hoxc9	homeobox C9	0.174
Gsc	goosecoid homeobox	0.171
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.171
Fbln5	fibulin 5	0.170
Srcin1	SRC kinase signaling inhibitor 1	0.170
Dhh	desert hedgehog	0.170
Scara3	scavenger receptor class A, member 3	0.169
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.169
Rhoj	ras homolog gene family, member J	0.168
Ptgfr	prostaglandin F receptor	0.168
Fmod	fibromodulin	0.168	Mouse
Msh2	mutS homolog 2 (E. coli)	0.168
Barx1	BarH-like homeobox 1	0.166
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.165
Fgf10	fibroblast growth factor 10	0.165
Grb2	growth factor receptor bound protein 2	0.164
Wnt6	wingless-related MMTV integration site 6	0.162	Mouse
Islr	immunoglobulin superfamily containing leucine-rich repeat	0.162
Hmx1	H6 homeobox 1	0.162
Bmp6	bone morphogenetic protein 6	0.161	Human Mouse
Mybph	myosin binding protein H	0.160
Pde3a	phosphodiesterase 3A, cGMP inhibited	0.160
Npr3	natriuretic peptide receptor 3	0.159
Lepr	leptin receptor	0.159
Lox	lysyl oxidase	0.159
Lpar1	lysophosphatidic acid receptor 1	0.154
Fbln2	fibulin 2	0.154
Gli1	GLI-Kruppel family member GLI1	0.154
Lhx1	LIM homeobox protein 1	0.153
Itga8	integrin alpha 8	0.153
Manf	mesencephalic astrocyte-derived neurotrophic factor	0.153
Pcdh18	protocadherin 18	0.153
Foxb2	forkhead box B2	0.151	Mouse
Fzd7	frizzled homolog 7 (Drosophila)	0.150	Mouse
Tnfrsf19	tumor necrosis factor receptor superfamily, member 19	0.150
Lbx1	ladybird homeobox homolog 1 (Drosophila)	0.149
Efna2	ephrin A2	0.149
Ddr2	discoidin domain receptor family, member 2	0.149
Shox2	short stature homeobox 2	0.148
Kcnj3	potassium inwardly-rectifying channel, subfamily J, member 3	0.148
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.148
Wnt7b	wingless-related MMTV integration site 7B	0.147	Mouse
Bptf	bromodomain PHD finger transcription factor	0.147
Foxo3	forkhead box O3	0.147	Fly
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.146
Tbx15	T-box 15	0.146	Mouse
Wt1	Wilms tumor 1 homolog	0.146
Emp2	epithelial membrane protein 2	0.145
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.144
Nppc	natriuretic peptide type C	0.143
Gja3	gap junction protein, alpha 3	0.142
Epha4	Eph receptor A4	0.140
Myl9	myosin, light polypeptide 9, regulatory	0.140
Fzd4	frizzled homolog 4 (Drosophila)	0.139	Mouse
Adra2a	adrenergic receptor, alpha 2a	0.139
Pdgfb	platelet derived growth factor, B polypeptide	0.139
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.139
Tcf15	transcription factor 15	0.139
T	brachyury	0.139	Zebrafish Mouse
Fjx1	four jointed box 1 (Drosophila)	0.139
Pou3f1	POU domain, class 3, transcription factor 1	0.138
S1pr3	sphingosine-1-phosphate receptor 3	0.138
Dkk3	dickkopf homolog 3 (Xenopus laevis)	0.138
Efna4	ephrin A4	0.137
Pcdh12	protocadherin 12	0.137
Grin2d	glutamate receptor, ionotropic, NMDA2D (epsilon 4)	0.137
Fmn1	formin 1	0.137
Fgf4	fibroblast growth factor 4	0.136	Mouse
Smoc2	SPARC related modular calcium binding 2	0.136
Pax2	paired box gene 2	0.136
Foxo1	forkhead box O1	0.135	Fly
Tcf21	transcription factor 21	0.135
Igfbp5	insulin-like growth factor binding protein 5	0.134
Msx1	homeobox, msh-like 1	0.134
Nfib	nuclear factor I/B	0.134
Wnt10b	wingless related MMTV integration site 10b	0.133	Mouse
Ptch1	patched homolog 1	0.132
Rara	retinoic acid receptor, alpha	0.132
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.132
Pkdcc	protein kinase domain containing, cytoplasmic	0.131
Wnt9a	wingless-type MMTV integration site 9A	0.131	Mouse
Kiss1	KiSS-1 metastasis-suppressor	0.130
Matn3	matrilin 3	0.130
Mtl5	metallothionein-like 5, testis-specific (tesmin)	0.130
Acan	aggrecan	0.129
Pgr	progesterone receptor	0.129
Efna5	ephrin A5	0.129
Ctgf	connective tissue growth factor	0.128
Col4a3	collagen, type IV, alpha 3	0.127
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.126
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.125
Lhfp	lipoma HMGIC fusion partner	0.125
Gbx2	gastrulation brain homeobox 2	0.124
Sall3	sal-like 3 (Drosophila)	0.123
Zic2	zinc finger protein of the cerebellum 2	0.122
Fgf17	fibroblast growth factor 17	0.122
Ptprb	protein tyrosine phosphatase, receptor type, B	0.121
Sema5a	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.120
Lama1	laminin, alpha 1	0.120
Alx3	aristaless-like homeobox 3	0.120
Nkx6-1	NK6 homeobox 1	0.119
Hoxb13	homeobox B13	0.119	Mouse
Grin2a	glutamate receptor, ionotropic, NMDA2A (epsilon 1)	0.118
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.118
Svep1	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1	0.116
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.116
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.116
Plat	plasminogen activator, tissue	0.116
Fgf14	fibroblast growth factor 14	0.116	Mouse
Adra1a	adrenergic receptor, alpha 1a	0.115
Ascl2	achaete-scute complex homolog 2 (Drosophila)	0.115
Zfhx4	zinc finger homeodomain 4	0.115
Pax5	paired box gene 5	0.114
Sema3c	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	0.114
Otp	orthopedia homolog (Drosophila)	0.114
Emid2	EMI domain containing 2	0.113
Bgn	biglycan	0.113	Mouse
Cbln3	cerebellin 3 precursor protein	0.113
Mecom	MDS1 and EVI1 complex locus	0.112	Mouse
Cbl	Casitas B-lineage lymphoma	0.112
Nos2	nitric oxide synthase 2, inducible	0.112
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.111
Ndel1	nuclear distribution gene E-like homolog 1 (A. nidulans)	0.111
Lrp6	low density lipoprotein receptor-related protein 6	0.111
Met	met proto-oncogene	0.110
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.109
Dnahc5	dynein, axonemal, heavy chain 5	0.109
Jag2	jagged 2	0.109
Foxf2	forkhead box F2	0.109
Sh3pxd2a	SH3 and PX domains 2A	0.108
Creb3l1	cAMP responsive element binding protein 3-like 1	0.107
Aebp1	AE binding protein 1	0.107
Smad2	MAD homolog 2 (Drosophila)	0.107	Human Mouse
Alx1	ALX homeobox 1	0.107
Sod3	superoxide dismutase 3, extracellular	0.106
Tmed8	transmembrane emp24 domain containing 8	0.106
Zfp651	zinc finger protein 651	0.106
Htra3	HtrA serine peptidase 3	0.105
Cdh11	cadherin 11	0.105
Nr0b1	nuclear receptor subfamily 0, group B, member 1	0.105
Pld2	phospholipase D2	0.105
Cx3cr1	chemokine (C-X3-C) receptor 1	0.105
Pitx1	paired-like homeodomain transcription factor 1	0.105
Ptgfrn	prostaglandin F2 receptor negative regulator	0.104
Il6st	interleukin 6 signal transducer	0.104
Crabp2	cellular retinoic acid binding protein II	0.104
Fut7	fucosyltransferase 7	0.104
Dlx6	distal-less homeobox 6	0.104
Zic1	zinc finger protein of the cerebellum 1	0.104
Adam12	a disintegrin and metallopeptidase domain 12 (meltrin alpha)	0.103	Mouse
Adra2b	adrenergic receptor, alpha 2b	0.103
Matn4	matrilin 4	0.103
Fhl3	four and a half LIM domains 3	0.102
Nes	nestin	0.102
Smtn	smoothelin	0.102
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.102
Loxl1	lysyl oxidase-like 1	0.102
Wnt7a	wingless-related MMTV integration site 7A	0.102	Mouse
Nkd2	naked cuticle 2 homolog (Drosophila)	0.101
Pkd1	polycystic kidney disease 1 homolog	0.101
She	src homology 2 domain-containing transforming protein E	0.101
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.100
Xiap	X-linked inhibitor of apoptosis	0.099
Myo10	myosin X	0.099
Efna1	ephrin A1	0.098
Foxl2	forkhead box L2	0.098	Mouse
Col1a2	collagen, type I, alpha 2	0.098
Jup	junction plakoglobin	0.098
Pvrl1	poliovirus receptor-related 1	0.098
Tbx5	T-box 5	0.098	Mouse
Srpx	sushi-repeat-containing protein	0.098
Emx2	empty spiracles homolog 2 (Drosophila)	0.097
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.097
Irx4	Iroquois related homeobox 4 (Drosophila)	0.097
Fscn3	fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus)	0.097
Helt	Hey-like transcription factor (zebrafish)	0.097
Fgf18	fibroblast growth factor 18	0.097
Acvr1b	activin A receptor, type 1B	0.096	Human Mouse Rat Fly
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.096
Neurog2	neurogenin 2	0.095
Masp1	mannan-binding lectin serine peptidase 1	0.095
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.095
Cdh3	cadherin 3	0.095
Art5	ADP-ribosyltransferase 5	0.094
Odz4	odd Oz/ten-m homolog 4 (Drosophila)	0.094
Btbd17	BTB (POZ) domain containing 17	0.094
Dmrt3	doublesex and mab-3 related transcription factor 3	0.094	Mouse
Wnt2b	wingless related MMTV integration site 2b	0.093	Mouse
Trpc5	transient receptor potential cation channel, subfamily C, member 5	0.093
Thbs2	thrombospondin 2	0.093	Mouse
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.093
Adrb1	adrenergic receptor, beta 1	0.093
Prlr	prolactin receptor	0.092
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.092
Epha3	Eph receptor A3	0.092
Phox2b	paired-like homeobox 2b	0.092
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.092
Tnks1bp1	tankyrase 1 binding protein 1	0.091
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.091	Fly
Fgf20	fibroblast growth factor 20	0.091
Epn3	epsin 3	0.090
Gpc4	glypican 4	0.090	Mouse
Ggt1	gamma-glutamyltransferase 1	0.090
Fosl2	fos-like antigen 2	0.090
Fgfr3	fibroblast growth factor receptor 3	0.090
Esrrb	estrogen related receptor, beta	0.090
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.090
Cyp26c1	cytochrome P450, family 26, subfamily c, polypeptide 1	0.090
Edn3	endothelin 3	0.090
Lcor	ligand dependent nuclear receptor corepressor	0.090
Cldn7	claudin 7	0.089
Pofut1	protein O-fucosyltransferase 1	0.089
Esam	endothelial cell-specific adhesion molecule	0.089
Cmklr1	chemokine-like receptor 1	0.089
Cabp7	calcium binding protein 7	0.089
Galnt6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6	0.089
Wfikkn1	WAP, FS, Ig, KU, and NTR-containing protein 1	0.088
Arvcf	armadillo repeat gene deleted in velo-cardio-facial syndrome	0.088
Sox21	SRY-box containing gene 21	0.088
Foxa1	forkhead box A1	0.088	Mouse
Ube2g1	ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans)	0.087
Trp53bp1	transformation related protein 53 binding protein 1	0.087
Dpysl3	dihydropyrimidinase-like 3	0.087
Slc5a5	solute carrier family 5 (sodium iodide symporter), member 5	0.087
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.086
Emx1	empty spiracles homolog 1 (Drosophila)	0.086
Cux1	cut-like homeobox 1	0.086	Mouse
Foxk1	forkhead box K1	0.086
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.086	Human Mouse
Pxdn	peroxidasin homolog (Drosophila)	0.086
Kif3a	kinesin family member 3A	0.086
Mfap4	microfibrillar-associated protein 4	0.086
Kitl	kit ligand	0.085
Inpp5d	inositol polyphosphate-5-phosphatase D	0.085
Egfr	epidermal growth factor receptor	0.085
Cdx1	caudal type homeobox 1	0.085
Zscan2	zinc finger and SCAN domain containing 2	0.085
Nobox	NOBOX oogenesis homeobox	0.085
Evx1	even skipped homeotic gene 1 homolog	0.085
Arsi	arylsulfatase i	0.085
Tgfb1i1	transforming growth factor beta 1 induced transcript 1	0.084	Human
Aldh1a3	aldehyde dehydrogenase family 1, subfamily A3	0.084
Onecut2	one cut domain, family member 2	0.084
Apcdd1	adenomatosis polyposis coli down-regulated 1	0.084
Lrp5	low density lipoprotein receptor-related protein 5	0.084
Bmp1	bone morphogenetic protein 1	0.084
Cdh1	cadherin 1	0.084
Sdc3	syndecan 3	0.084
Cnn1	calponin 1	0.083
Enc1	ectodermal-neural cortex 1	0.083
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.083
Ptk2	PTK2 protein tyrosine kinase 2	0.082
Gdf10	growth differentiation factor 10	0.082	Mouse
Tmem132c	transmembrane protein 132C	0.082
C1qtnf1	C1q and tumor necrosis factor related protein 1	0.082
St3gal2	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	0.082
Asb10	ankyrin repeat and SOCS box-containing 10	0.082
Cachd1	cache domain containing 1	0.081
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.080
Cdkn1c	cyclin-dependent kinase inhibitor 1C (P57)	0.080	Human
Fzd9	frizzled homolog 9 (Drosophila)	0.080	Mouse
Clcn1	chloride channel 1	0.080
Amotl2	angiomotin-like 2	0.080
4931408A02Rik	RIKEN cDNA 4931408A02 gene	0.080
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.079
Npc1	Niemann Pick type C1	0.079
Wwtr1	WW domain containing transcription regulator 1	0.079	Human
Tead2	TEA domain family member 2	0.079
Kdm5a	lysine (K)-specific demethylase 5A	0.078
Nptx2	neuronal pentraxin 2	0.078
Myog	myogenin	0.078
Ano1	anoctamin 1, calcium activated chloride channel	0.078
Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.078
Mesp1	mesoderm posterior 1	0.078
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.078
En2	engrailed 2	0.077
Per3	period homolog 3 (Drosophila)	0.077
Hbegf	heparin-binding EGF-like growth factor	0.077
Bnc1	basonuclin 1	0.077
Dlx4	distal-less homeobox 4	0.076
Fzd2	frizzled homolog 2 (Drosophila)	0.076	Mouse
Wdr86	WD repeat domain 86	0.076
Eras	ES cell-expressed Ras	0.076
Lif	leukemia inhibitory factor	0.076
Mgp	matrix Gla protein	0.076
Scn5a	sodium channel, voltage-gated, type V, alpha	0.076
Irx1	Iroquois related homeobox 1 (Drosophila)	0.076
Neurog1	neurogenin 1	0.076
Ngf	nerve growth factor	0.075
Prph2	peripherin 2	0.075
Kcnj6	potassium inwardly-rectifying channel, subfamily J, member 6	0.075
Pgf	placental growth factor	0.075
Thpo	thrombopoietin	0.075
Ephb2	Eph receptor B2	0.075
Il10	interleukin 10	0.075
Pds5b	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.075
Mknk2	MAP kinase-interacting serine/threonine kinase 2	0.075
Ets1	E26 avian leukemia oncogene 1, 5' domain	0.074
Sox1	SRY-box containing gene 1	0.074
Cdh6	cadherin 6	0.074
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.074
Fzd10	frizzled homolog 10 (Drosophila)	0.074
Scn3a	sodium channel, voltage-gated, type III, alpha	0.074
Tll1	tolloid-like	0.073	Zebrafish
Tnfrsf25	tumor necrosis factor receptor superfamily, member 25	0.073
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.073
Sh3rf1	SH3 domain containing ring finger 1	0.073
Skil	SKI-like	0.073
Arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.073
Lefty2	left-right determination factor 2	0.073	Mouse
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.073
Podxl	podocalyxin-like	0.073
Mstn	myostatin	0.073
Maf	avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog	0.073
Sfrp5	secreted frizzled-related sequence protein 5	0.072	Mouse
Abl2	v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)	0.072	Mouse
Chrnd	cholinergic receptor, nicotinic, delta polypeptide	0.072
Adora2b	adenosine A2b receptor	0.072
Pea15a	phosphoprotein enriched in astrocytes 15A	0.072
Rnf111	ring finger 111	0.071
Apaf1	apoptotic peptidase activating factor 1	0.071
Fzd6	frizzled homolog 6 (Drosophila)	0.071	Mouse
Ier3	immediate early response 3	0.071
Tnc	tenascin C	0.071
Ltbp4	latent transforming growth factor beta binding protein 4	0.071
Col4a4	collagen, type IV, alpha 4	0.071
Prkd1	protein kinase D1	0.070
Cntfr	ciliary neurotrophic factor receptor	0.070
Pik3c2a	phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide	0.070
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.070	Mouse
Npr1	natriuretic peptide receptor 1	0.070
Notch3	Notch gene homolog 3 (Drosophila)	0.070	Mouse
Zfp703	zinc finger protein 703	0.069
Cnpy1	canopy 1 homolog (zebrafish)	0.069
Rem1	rad and gem related GTP binding protein 1	0.069
Map3k2	mitogen-activated protein kinase kinase kinase 2	0.069
Slit3	slit homolog 3 (Drosophila)	0.069
Esx1	extraembryonic, spermatogenesis, homeobox 1	0.069
Tinagl1	tubulointerstitial nephritis antigen-like 1	0.069
Mrc2	mannose receptor, C type 2	0.068
Bmp8a	bone morphogenetic protein 8a	0.068	Mouse
Dll1	delta-like 1 (Drosophila)	0.068
2700081O15Rik	RIKEN cDNA 2700081O15 gene	0.068
Ntf3	neurotrophin 3	0.068
Tcf7	transcription factor 7, T-cell specific	0.068	Mouse
Sema5b	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B	0.068
Megf8	multiple EGF-like-domains 8	0.068
Tgfb3	transforming growth factor, beta 3	0.067
Epha1	Eph receptor A1	0.067
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.067
Npas2	neuronal PAS domain protein 2	0.067
Etv2	ets variant gene 2	0.067
Vegfc	vascular endothelial growth factor C	0.067
Myc	myelocytomatosis oncogene	0.067
Igf1r	insulin-like growth factor I receptor	0.067
Pdgfa	platelet derived growth factor, alpha	0.067
Mnx1	motor neuron and pancreas homeobox 1	0.067
Crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.066
Dok1	docking protein 1	0.066
Sh3pxd2b	SH3 and PX domains 2B	0.066
Lyzl4	lysozyme-like 4	0.066
Dag1	dystroglycan 1	0.066
Cacna1g	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.066
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.066
Serpina5	serine (or cysteine) peptidase inhibitor, clade A, member 5	0.066
Glis1	GLIS family zinc finger 1	0.066
Adamts2	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2	0.066
Mbd3	methyl-CpG binding domain protein 3	0.066
Galr2	galanin receptor 2	0.066
Notch2	Notch gene homolog 2 (Drosophila)	0.065
Plin1	perilipin 1	0.065
Nbl1	neuroblastoma, suppression of tumorigenicity 1	0.065
Foxd3	forkhead box D3	0.065	Mouse
BC021891	cDNA sequence BC021891	0.065
Syt7	synaptotagmin VII	0.065
F2r	coagulation factor II (thrombin) receptor	0.065
Mmp2	matrix metallopeptidase 2	0.065
P2ry2	purinergic receptor P2Y, G-protein coupled 2	0.065
Tcte3	t-complex-associated testis expressed 3	0.065
Tagln	transgelin	0.065
Igfbp6	insulin-like growth factor binding protein 6	0.065
Lefty1	left right determination factor 1	0.065
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.065
Pyy	peptide YY	0.065
Has2	hyaluronan synthase 2	0.064	Zebrafish
Meox1	mesenchyme homeobox 1	0.064
Tmeff2	transmembrane protein with EGF-like and two follistatin-like domains 2	0.064
Mmp9	matrix metallopeptidase 9	0.064
Col6a2	collagen, type VI, alpha 2	0.064
Fgfbp1	fibroblast growth factor binding protein 1	0.064
Rdh10	retinol dehydrogenase 10 (all-trans)	0.064
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.064
Rfwd2	ring finger and WD repeat domain 2	0.064
Gfpt2	glutamine fructose-6-phosphate transaminase 2	0.064
Chst2	carbohydrate sulfotransferase 2	0.064
Cdh13	cadherin 13	0.064
Il25	interleukin 25	0.064
Ppfia4	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4	0.063
Sema4b	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B	0.063
Cdc42ep1	CDC42 effector protein (Rho GTPase binding) 1	0.063
Slc22a6	solute carrier family 22 (organic anion transporter), member 6	0.063
Dmtf1	cyclin D binding myb-like transcription factor 1	0.063
Rax	retina and anterior neural fold homeobox	0.063
Nde1	nuclear distribution gene E homolog 1 (A nidulans)	0.063
Ednra	endothelin receptor type A	0.063
Tas1r1	taste receptor, type 1, member 1	0.063
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.063
Isl2	insulin related protein 2 (islet 2)	0.062
Irx3	Iroquois related homeobox 3 (Drosophila)	0.062
Col2a1	collagen, type II, alpha 1	0.062
E2f1	E2F transcription factor 1	0.062
Klf4	Kruppel-like factor 4 (gut)	0.062
Ybx2	Y box protein 2	0.062
Gdf6	growth differentiation factor 6	0.062	Human Zebrafish Mouse
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.062
Cdk14	cyclin-dependent kinase 14	0.062
Cxadr	coxsackie virus and adenovirus receptor	0.062
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.062
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.062
Tcfap2d	transcription factor AP-2, delta	0.062
C3ar1	complement component 3a receptor 1	0.062
Col4a5	collagen, type IV, alpha 5	0.062
Pou3f2	POU domain, class 3, transcription factor 2	0.062
Foxd2	forkhead box D2	0.061	Mouse
Gcnt2	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme	0.061
Pdx1	pancreatic and duodenal homeobox 1	0.061
Eya4	eyes absent 4 homolog (Drosophila)	0.061
Sulf1	sulfatase 1	0.061	Human Fly
Nr6a1	nuclear receptor subfamily 6, group A, member 1	0.061
Thbd	thrombomodulin	0.061
Tmem30a	transmembrane protein 30A	0.061
Nfatc1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.061
Adam23	a disintegrin and metallopeptidase domain 23	0.061	Mouse
Nid1	nidogen 1	0.061
Zfp36l2	zinc finger protein 36, C3H type-like 2	0.061
Il11	interleukin 11	0.061
Myo1e	myosin IE	0.060
Kcnk3	potassium channel, subfamily K, member 3	0.060
Stk3	serine/threonine kinase 3 (Ste20, yeast homolog)	0.060
Sp5	trans-acting transcription factor 5	0.060
Msi1	Musashi homolog 1(Drosophila)	0.060
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.060
Socs1	suppressor of cytokine signaling 1	0.060
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.060
Clock	circadian locomotor output cycles kaput	0.059
Gab1	growth factor receptor bound protein 2-associated protein 1	0.059
Fgf2	fibroblast growth factor 2	0.059	Mouse
Vgll1	vestigial like 1 homolog (Drosophila)	0.059
Vhl	von Hippel-Lindau tumor suppressor	0.059
Papln	papilin, proteoglycan-like sulfated glycoprotein	0.059
Apba2	amyloid beta (A4) precursor protein-binding, family A, member 2	0.059
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.059
Ccl24	chemokine (C-C motif) ligand 24	0.059
Kcna1	potassium voltage-gated channel, shaker-related subfamily, member 1	0.059
Nuak1	NUAK family, SNF1-like kinase, 1	0.059
Sox13	SRY-box containing gene 13	0.059
Tbx6	T-box 6	0.059	Mouse
Tlr4	toll-like receptor 4	0.059
Cxcr4	chemokine (C-X-C motif) receptor 4	0.059
Nlrp5	NLR family, pyrin domain containing 5	0.058
Pkdrej	polycystic kidney disease (polycystin) and REJ (sperm receptor for egg jelly, sea urchin homolog)-like	0.058
Fgf16	fibroblast growth factor 16	0.058	Mouse
Gja4	gap junction protein, alpha 4	0.058
Gja10	gap junction protein, alpha 10	0.058
Lhx6	LIM homeobox protein 6	0.058
Foxb1	forkhead box B1	0.058
Cacng6	calcium channel, voltage-dependent, gamma subunit 6	0.058
Epha2	Eph receptor A2	0.058
Fzd3	frizzled homolog 3 (Drosophila)	0.058	Mouse
Cacnb2	calcium channel, voltage-dependent, beta 2 subunit	0.058
Tulp1	tubby like protein 1	0.058
Cdk5r2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.058
Klk4	kallikrein related-peptidase 4 (prostase, enamel matrix, prostate)	0.058
Kif1b	kinesin family member 1B	0.058
Il17d	interleukin 17D	0.058
Rac1	RAS-related C3 botulinum substrate 1	0.058
Flt1	FMS-like tyrosine kinase 1	0.057	Mouse
Pthlh	parathyroid hormone-like peptide	0.057
Ppard	peroxisome proliferator activator receptor delta	0.057
Cd97	CD97 antigen	0.057
Fuz	fuzzy homolog (Drosophila)	0.057
Klk6	kallikrein related-peptidase 6	0.057
Shroom1	shroom family member 1	0.057
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.057
Tcfcp2l1	transcription factor CP2-like 1	0.057
Krt82	keratin 82	0.057
Rap2b	RAP2B, member of RAS oncogene family	0.057
Vipr2	vasoactive intestinal peptide receptor 2	0.057
Tll2	tolloid-like 2	0.057	Zebrafish
Ext1	exostoses (multiple) 1	0.057
Cyr61	cysteine rich protein 61	0.056	Human
Psen1	presenilin 1	0.056
Pdcd1	programmed cell death 1	0.056
Gucy1b3	guanylate cyclase 1, soluble, beta 3	0.056
Runx1	runt related transcription factor 1	0.056
Pbx1	pre B-cell leukemia transcription factor 1	0.056
Egr1	early growth response 1	0.056
Mknk1	MAP kinase-interacting serine/threonine kinase 1	0.056
Flnc	filamin C, gamma	0.056
Phox2a	paired-like homeobox 2a	0.056
Adam15	a disintegrin and metallopeptidase domain 15 (metargidin)	0.056	Mouse
Trpv4	transient receptor potential cation channel, subfamily V, member 4	0.055
Lum	lumican	0.055	Mouse
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.055
Angpt1	angiopoietin 1	0.055
Tle1	transducin-like enhancer of split 1, homolog of Drosophila E(spl)	0.055
Ky	kyphoscoliosis peptidase	0.055
Foxp2	forkhead box P2	0.055
Pfkfb2	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2	0.055
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.055
Vax1	ventral anterior homeobox containing gene 1	0.055
Pvr	poliovirus receptor	0.055
Zfhx3	zinc finger homeobox 3	0.055
Hoxd1	homeobox D1	0.055
Foxq1	forkhead box Q1	0.055	Mouse
Plcd1	phospholipase C, delta 1	0.055
Spin1	spindlin 1	0.055
Hoxa10	homeobox A10	0.055
Dffb	DNA fragmentation factor, beta subunit	0.055
Zeb1	zinc finger E-box binding homeobox 1	0.055
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.055
C230081A13Rik	RIKEN cDNA C230081A13 gene	0.055
Zfpm2	zinc finger protein, multitype 2	0.054
Rln1	relaxin 1	0.054
Nr5a2	nuclear receptor subfamily 5, group A, member 2	0.054
Cxcl14	chemokine (C-X-C motif) ligand 14	0.054
Hipk3	homeodomain interacting protein kinase 3	0.054
Hspb8	heat shock protein 8	0.054
B3galt1	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1	0.054
Pam	peptidylglycine alpha-amidating monooxygenase	0.054
Sp6	trans-acting transcription factor 6	0.054
D1Pas1	DNA segment, Chr 1, Pasteur Institute 1	0.054
Fndc7	fibronectin type III domain containing 7	0.054
Rnf103	ring finger protein 103	0.054
Rasip1	Ras interacting protein 1	0.054
Neo1	neogenin	0.053
Irs4	insulin receptor substrate 4	0.053	Fly
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.053
Trpm6	transient receptor potential cation channel, subfamily M, member 6	0.053
Cpd	carboxypeptidase D	0.053
Cldn3	claudin 3	0.053
Cry1	cryptochrome 1 (photolyase-like)	0.053
Ndfip1	Nedd4 family interacting protein 1	0.053
Igfals	insulin-like growth factor binding protein, acid labile subunit	0.053
Col5a2	collagen, type V, alpha 2	0.053