IMP
Process View
signal transduction involved in dna integrity checkpoint
A signal transduction process that contributes to a DNA integrity checkpoint.
Loading network...
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "signal transduction involved in dna integrity checkpoint"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Trp53 | transformation related protein 53 | 1.000 | ||
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.994 | Human | |
| Pten | phosphatase and tensin homolog | 0.992 | ||
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.989 | Human | |
| Mdm4 | transformed mouse 3T3 cell double minute 4 | 0.962 | ||
| Apc | adenomatosis polyposis coli | 0.938 | ||
| Rb1 | retinoblastoma 1 | 0.936 | ||
| Brca1 | breast cancer 1 | 0.912 | ||
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.868 | ||
| Col1a1 | collagen, type I, alpha 1 | 0.809 | ||
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.784 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.729 | ||
| Brca2 | breast cancer 2 | 0.682 | ||
| Kit | kit oncogene | 0.564 | ||
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.490 | ||
| Rara | retinoic acid receptor, alpha | 0.340 | ||
| Skil | SKI-like | 0.336 | ||
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.316 | ||
| Daxx | Fas death domain-associated protein | 0.314 | ||
| Cdkn2a | cyclin-dependent kinase inhibitor 2A | 0.309 | ||
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.295 | ||
| Braf | Braf transforming gene | 0.292 | ||
| Thbs1 | thrombospondin 1 | 0.234 | ||
| Prkdc | protein kinase, DNA activated, catalytic polypeptide | 0.232 | ||
| Sfn | stratifin | 0.226 | ||
| Stk11 | serine/threonine kinase 11 | 0.202 | ||
| Nbn | nibrin | 0.186 | ||
| Trp63 | transformation related protein 63 | 0.180 | Mouse | |
| Runx1 | runt related transcription factor 1 | 0.148 | ||
| Meox2 | mesenchyme homeobox 2 | 0.139 | ||
| E2f1 | E2F transcription factor 1 | 0.128 | ||
| Nf1 | neurofibromatosis 1 | 0.122 | ||
| Hipk1 | homeodomain interacting protein kinase 1 | 0.118 | ||
| Trp73 | transformation related protein 73 | 0.109 | Mouse | |
| Ccnd1 | cyclin D1 | 0.108 | ||
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.106 | ||
| Atm | ataxia telangiectasia mutated homolog (human) | 0.103 | Human | |
| Rxra | retinoid X receptor alpha | 0.089 | ||
| Wrn | Werner syndrome homolog (human) | 0.077 | ||
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.073 | ||
| Stat3 | signal transducer and activator of transcription 3 | 0.064 | ||
| Sox9 | SRY-box containing gene 9 | 0.061 | ||
| Rbl1 | retinoblastoma-like 1 (p107) | 0.057 | ||
| Ptch1 | patched homolog 1 | 0.054 | ||
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.049 | ||
| Tgfb1 | transforming growth factor, beta 1 | 0.049 | ||
| Ndufv1 | NADH dehydrogenase (ubiquinone) flavoprotein 1 | 0.044 | ||
| Sin3a | transcriptional regulator, SIN3A (yeast) | 0.044 | ||
| Cdkn2c | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.043 | ||
| Cldn7 | claudin 7 | 0.043 | ||
| Mybl2 | myeloblastosis oncogene-like 2 | 0.041 | ||
| Vhl | von Hippel-Lindau tumor suppressor | 0.040 | ||
| Esr1 | estrogen receptor 1 (alpha) | 0.037 | ||
| Vdr | vitamin D receptor | 0.036 | ||
| Adam17 | a disintegrin and metallopeptidase domain 17 | 0.036 | ||
| Elavl1 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) | 0.036 | ||
| Smad3 | MAD homolog 3 (Drosophila) | 0.035 | ||
| Yap1 | yes-associated protein 1 | 0.035 | ||
| Msh2 | mutS homolog 2 (E. coli) | 0.033 | ||
| Nf2 | neurofibromatosis 2 | 0.032 | ||
| Huwe1 | HECT, UBA and WWE domain containing 1 | 0.031 | ||
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.029 | ||
| Rassf1 | Ras association (RalGDS/AF-6) domain family member 1 | 0.029 | ||
| Dok1 | docking protein 1 | 0.029 | ||
| Il6st | interleukin 6 signal transducer | 0.029 | ||
| Nfya | nuclear transcription factor-Y alpha | 0.028 | ||
| Gadd45a | growth arrest and DNA-damage-inducible 45 alpha | 0.028 | ||
| Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.027 | ||
| Xpa | xeroderma pigmentosum, complementation group A | 0.026 | ||
| Tia1 | cytotoxic granule-associated RNA binding protein 1 | 0.026 | ||
| Lig4 | ligase IV, DNA, ATP-dependent | 0.026 | ||
| Smad5 | MAD homolog 5 (Drosophila) | 0.025 | ||
| Ahr | aryl-hydrocarbon receptor | 0.024 | ||
| Pms2 | postmeiotic segregation increased 2 (S. cerevisiae) | 0.024 | ||
| Asxl1 | additional sex combs like 1 (Drosophila) | 0.024 | ||
| Mlh1 | mutL homolog 1 (E. coli) | 0.024 | ||
| Shh | sonic hedgehog | 0.023 | ||
| Hhat | hedgehog acyltransferase | 0.022 | ||
| Tsc1 | tuberous sclerosis 1 | 0.022 | ||
| Gata3 | GATA binding protein 3 | 0.022 | ||
| Kitl | kit ligand | 0.022 | ||
| Rnf8 | ring finger protein 8 | 0.022 | ||
| Hr | hairless | 0.022 | ||
| Psen1 | presenilin 1 | 0.021 | ||
| Lyz2 | lysozyme 2 | 0.021 | ||
| Fadd | Fas (TNFRSF6)-associated via death domain | 0.020 | ||
| Fbn1 | fibrillin 1 | 0.020 | ||
| Crlf3 | cytokine receptor-like factor 3 | 0.020 | ||
| Tcf3 | transcription factor 3 | 0.020 | ||
| Timm13 | translocase of inner mitochondrial membrane 13 homolog (yeast) | 0.020 | ||
| Cxcr4 | chemokine (C-X-C motif) receptor 4 | 0.020 | ||
| Fas | Fas (TNF receptor superfamily member 6) | 0.020 | ||
| Hoxa13 | homeobox A13 | 0.019 | ||
| Smn1 | survival motor neuron 1 | 0.019 | ||
| Irf6 | interferon regulatory factor 6 | 0.019 | ||
| Elf3 | E74-like factor 3 | 0.019 | ||
| Eif2ak2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.019 | ||
| Pds5b | PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) | 0.019 | ||
| Nfe2l2 | nuclear factor, erythroid derived 2, like 2 | 0.019 | ||
| Itga3 | integrin alpha 3 | 0.018 | ||
| Cdx2 | caudal type homeobox 2 | 0.018 | ||
| Esr2 | estrogen receptor 2 (beta) | 0.018 | ||
| Lmna | lamin A | 0.018 | ||
| Csf1 | colony stimulating factor 1 (macrophage) | 0.018 | ||
| Lepr | leptin receptor | 0.018 | ||
| Lgals9 | lectin, galactose binding, soluble 9 | 0.017 | ||
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.017 | ||
| Cbl | Casitas B-lineage lymphoma | 0.017 | ||
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.017 | ||
| Htatip2 | HIV-1 tat interactive protein 2, homolog (human) | 0.017 | ||
| Pkp3 | plakophilin 3 | 0.017 | ||
| Hjurp | Holliday junction recognition protein | 0.017 | ||
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.017 | ||
| Ndufs8 | NADH dehydrogenase (ubiquinone) Fe-S protein 8 | 0.017 | ||
| Zmym4 | zinc finger, MYM-type 4 | 0.017 | ||
| Ar | androgen receptor | 0.016 | ||
| Ifit1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.016 | ||
| Fam60a | family with sequence similarity 60, member A | 0.016 | ||
| Dicer1 | Dicer1, Dcr-1 homolog (Drosophila) | 0.016 | ||
| Smtn | smoothelin | 0.016 | ||
| Bard1 | BRCA1 associated RING domain 1 | 0.016 | ||
| Xrn1 | 5'-3' exoribonuclease 1 | 0.015 | ||
| Lyst | lysosomal trafficking regulator | 0.015 | ||
| Mbd4 | methyl-CpG binding domain protein 4 | 0.015 | ||
| Tnf | tumor necrosis factor | 0.015 | ||
| Telo2 | TEL2, telomere maintenance 2, homolog (S. cerevisiae) | 0.015 | ||
| Cdca7l | cell division cycle associated 7 like | 0.015 | ||
| Fancc | Fanconi anemia, complementation group C | 0.015 | ||
| Cdk6 | cyclin-dependent kinase 6 | 0.014 | ||
| Stat1 | signal transducer and activator of transcription 1 | 0.014 | ||
| Anapc1 | anaphase promoting complex subunit 1 | 0.014 | ||
| Krt19 | keratin 19 | 0.014 | ||
| Foxp1 | forkhead box P1 | 0.014 | ||
| Stk4 | serine/threonine kinase 4 | 0.014 | ||
| Cyc1 | cytochrome c-1 | 0.014 | ||
| Sp1 | trans-acting transcription factor 1 | 0.014 | ||
| Ets1 | E26 avian leukemia oncogene 1, 5' domain | 0.014 | ||
| Abl1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.014 | ||
| Nle1 | notchless homolog 1 (Drosophila) | 0.014 | ||
| Foxp3 | forkhead box P3 | 0.014 | ||
| Lamc2 | laminin, gamma 2 | 0.014 | ||
| Mapk8 | mitogen-activated protein kinase 8 | 0.014 | ||
| Egfr | epidermal growth factor receptor | 0.014 | ||
| Tapbp | TAP binding protein | 0.014 | ||
| Ncoa3 | nuclear receptor coactivator 3 | 0.013 | ||
| Trpc2 | transient receptor potential cation channel, subfamily C, member 2 | 0.013 | ||
| Ikbkb | inhibitor of kappaB kinase beta | 0.013 | ||
| Pml | promyelocytic leukemia | 0.013 | ||
| Uba7 | ubiquitin-like modifier activating enzyme 7 | 0.013 | ||
| Prps2 | phosphoribosyl pyrophosphate synthetase 2 | 0.013 | ||
| Stat5a | signal transducer and activator of transcription 5A | 0.013 | ||
| Cdk2 | cyclin-dependent kinase 2 | 0.013 | ||
| Mfng | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 0.013 | ||
| Il17re | interleukin 17 receptor E | 0.013 | ||
| Itgb4 | integrin beta 4 | 0.013 | ||
| Med23 | mediator complex subunit 23 | 0.013 | ||
| Mapk14 | mitogen-activated protein kinase 14 | 0.013 | ||
| Hltf | helicase-like transcription factor | 0.012 | ||
| Bglap2 | bone gamma-carboxyglutamate protein 2 | 0.012 | ||
| Casp2 | caspase 2 | 0.012 | Human | |
| Terf1 | telomeric repeat binding factor 1 | 0.012 | ||
| Myc | myelocytomatosis oncogene | 0.012 | ||
| Pask | PAS domain containing serine/threonine kinase | 0.012 | ||
| Ikbkg | inhibitor of kappaB kinase gamma | 0.012 | ||
| Ap1m2 | adaptor protein complex AP-1, mu 2 subunit | 0.012 | ||
| Mapkapk2 | MAP kinase-activated protein kinase 2 | 0.012 | ||
| Men1 | multiple endocrine neoplasia 1 | 0.012 | ||
| Ccnd3 | cyclin D3 | 0.012 | ||
| Zbtb32 | zinc finger and BTB domain containing 32 | 0.012 | ||
| Amhr2 | anti-Mullerian hormone type 2 receptor | 0.012 | ||
| Rbl2 | retinoblastoma-like 2 | 0.012 | ||
| Apobec3 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3 | 0.012 | ||
| Zfp26 | zinc finger protein 26 | 0.012 | ||
| Trim25 | tripartite motif-containing 25 | 0.011 | ||
| Rarb | retinoic acid receptor, beta | 0.011 | ||
| Lamb3 | laminin, beta 3 | 0.011 | ||
| Id1 | inhibitor of DNA binding 1 | 0.011 | ||
| Igbp1 | immunoglobulin (CD79A) binding protein 1 | 0.011 | ||
| Gna15 | guanine nucleotide binding protein, alpha 15 | 0.011 | ||
| Vegfa | vascular endothelial growth factor A | 0.011 | ||
| Lef1 | lymphoid enhancer binding factor 1 | 0.011 | ||
| Raf1 | v-raf-leukemia viral oncogene 1 | 0.011 | ||
| Efnb2 | ephrin B2 | 0.011 | ||
| Pgls | 6-phosphogluconolactonase | 0.011 | ||
| Polm | polymerase (DNA directed), mu | 0.011 | ||
| Setd8 | SET domain containing (lysine methyltransferase) 8 | 0.011 | ||
| Cenpa | centromere protein A | 0.011 | ||
| Ckap5 | cytoskeleton associated protein 5 | 0.011 | ||
| Tacstd2 | tumor-associated calcium signal transducer 2 | 0.011 | ||
| Nbeal2 | neurobeachin-like 2 | 0.011 | ||
| Bmp4 | bone morphogenetic protein 4 | 0.011 | ||
| Casp3 | caspase 3 | 0.011 | ||
| Ikbkap | inhibitor of kappa light polypeptide enhancer in B-cells, kinase complex-associated protein | 0.010 | ||
| Map3k7 | mitogen-activated protein kinase kinase kinase 7 | 0.010 | ||
| Rassf5 | Ras association (RalGDS/AF-6) domain family member 5 | 0.010 | ||
| Pparg | peroxisome proliferator activated receptor gamma | 0.010 | ||
| Rps6kb1 | ribosomal protein S6 kinase, polypeptide 1 | 0.010 | ||
| Irf9 | interferon regulatory factor 9 | 0.010 | ||
| Vill | villin-like | 0.010 | ||
| Stat6 | signal transducer and activator of transcription 6 | 0.010 | ||
| Cldn4 | claudin 4 | 0.010 | ||
| Pglyrp1 | peptidoglycan recognition protein 1 | 0.010 | ||
| St14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.010 | ||
| 4930579J09Rik | RIKEN cDNA 4930579J09 gene | 0.010 | ||
| Gtse1 | G two S phase expressed protein 1 | 0.010 | ||
| Sprr1a | small proline-rich protein 1A | 0.010 | ||
| Slc39a4 | solute carrier family 39 (zinc transporter), member 4 | 0.010 |