IMP: Integrative Multi-species Prediction

Mus musculus

306 genes annotated in mouse

apoptotic signaling pathway

A series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "apoptotic signaling pathway"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "apoptotic signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
Pten	phosphatase and tensin homolog	1.000
Ctnnb1	catenin (cadherin associated protein), beta 1	1.000
Trp53	transformation related protein 53	0.999
Mdm2	transformed mouse 3T3 cell double minute 2	0.999
Fas	Fas (TNF receptor superfamily member 6)	0.996
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.991	Mouse
Tnf	tumor necrosis factor	0.990
Rb1	retinoblastoma 1	0.987
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.985
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.985	Human
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.980	Mouse Fly
Lepr	leptin receptor	0.972
Bcl2	B-cell leukemia/lymphoma 2	0.968
Tgfb1	transforming growth factor, beta 1	0.965	Human Mouse
Brca1	breast cancer 1	0.965	Human
Rnf2	ring finger protein 2	0.960	Zebrafish
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.960
Casp8	caspase 8	0.960
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.958	Mouse
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.946
Ikzf1	IKAROS family zinc finger 1	0.942
Stk4	serine/threonine kinase 4	0.933
Tlr4	toll-like receptor 4	0.926
Ptgs2	prostaglandin-endoperoxide synthase 2	0.923
Vegfa	vascular endothelial growth factor A	0.922
Ikbkb	inhibitor of kappaB kinase beta	0.921
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.920	Mouse
Gdnf	glial cell line derived neurotrophic factor	0.919	Human
Runx1	runt related transcription factor 1	0.919	Mouse
Igh	immunoglobulin heavy chain complex	0.917
Nos3	nitric oxide synthase 3, endothelial cell	0.915
Col1a1	collagen, type I, alpha 1	0.914	Mouse
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.910
Rbl1	retinoblastoma-like 1 (p107)	0.900	Fly
Tcf21	transcription factor 21	0.893
Icos	inducible T-cell co-stimulator	0.888	Mouse
Itgal	integrin alpha L	0.884	Mouse
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.879
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.874
Casp3	caspase 3	0.870
Cd28	CD28 antigen	0.870
Ncoa3	nuclear receptor coactivator 3	0.867
Il2rb	interleukin 2 receptor, beta chain	0.857
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.854	Human
Msh2	mutS homolog 2 (E. coli)	0.847
Atm	ataxia telangiectasia mutated homolog (human)	0.846
Ntf3	neurotrophin 3	0.845	Mouse
Traf6	TNF receptor-associated factor 6	0.835
Ifng	interferon gamma	0.834
Acvr1	activin A receptor, type 1	0.833	Human Mouse
Fasl	Fas ligand (TNF superfamily, member 6)	0.822
Cdkn2d	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	0.821	Human
Cd4	CD4 antigen	0.814
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.813
Mmp9	matrix metallopeptidase 9	0.807
Skil	SKI-like	0.804
Nos1	nitric oxide synthase 1, neuronal	0.793
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.792
Ikbkg	inhibitor of kappaB kinase gamma	0.790
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.790
E2f1	E2F transcription factor 1	0.788
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.787	Mouse Fly
Hmgb1	high mobility group box 1	0.786	Mouse
Trp63	transformation related protein 63	0.786
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.779
Bax	BCL2-associated X protein	0.779
Myc	myelocytomatosis oncogene	0.777
Gpr132	G protein-coupled receptor 132	0.767
Casp1	caspase 1	0.765	Mouse Fly
Lbr	lamin B receptor	0.764
Amh	anti-Mullerian hormone	0.764
Sharpin	SHANK-associated RH domain interacting protein	0.762	Mouse
Cd151	CD151 antigen	0.749
Vhl	von Hippel-Lindau tumor suppressor	0.745
Inhba	inhibin beta-A	0.744	Human Mouse
Nfatc3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	0.744	Mouse
Hoxd13	homeobox D13	0.743
Krt17	keratin 17	0.742	Mouse
Nos2	nitric oxide synthase 2, inducible	0.734
Il2rg	interleukin 2 receptor, gamma chain	0.729
Thbs1	thrombospondin 1	0.726	Human
Bcl2l1	BCL2-like 1	0.721
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.721
Fst	follistatin	0.712
Sh2d2a	SH2 domain protein 2A	0.708
Mapk8	mitogen-activated protein kinase 8	0.705
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.703
Apc	adenomatosis polyposis coli	0.701
Cdk4	cyclin-dependent kinase 4	0.698
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.696
Fyn	Fyn proto-oncogene	0.695	Rat
Plcg1	phospholipase C, gamma 1	0.692
Ar	androgen receptor	0.689	Human
Tgfbr2	transforming growth factor, beta receptor II	0.688	Mouse
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.684
Rxra	retinoid X receptor alpha	0.680
Ldb3	LIM domain binding 3	0.680
Lck	lymphocyte protein tyrosine kinase	0.675	Human
Itgb3	integrin beta 3	0.673
Wwox	WW domain-containing oxidoreductase	0.669
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.666
Wrn	Werner syndrome homolog (human)	0.656
Cd19	CD19 antigen	0.656
Krt5	keratin 5	0.654	Mouse
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.653	Human Fly
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.652
Atf4	activating transcription factor 4	0.649
Ccr1	chemokine (C-C motif) receptor 1	0.649	Mouse
Trib3	tribbles homolog 3 (Drosophila)	0.645	Human
Cyld	cylindromatosis (turban tumor syndrome)	0.645	Human
Efnb2	ephrin B2	0.645
Hdac2	histone deacetylase 2	0.645
Phox2a	paired-like homeobox 2a	0.642
Cd44	CD44 antigen	0.641
Hdac1	histone deacetylase 1	0.640
Cd40	CD40 antigen	0.640	Mouse
Foxf1a	forkhead box F1a	0.639
Tnip1	TNFAIP3 interacting protein 1	0.638
Ccnd1	cyclin D1	0.633
Spry4	sprouty homolog 4 (Drosophila)	0.631
Mapk3	mitogen-activated protein kinase 3	0.630
Fgf5	fibroblast growth factor 5	0.629	Mouse
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.628
Nf1	neurofibromatosis 1	0.627
App	amyloid beta (A4) precursor protein	0.626
Bmi1	Bmi1 polycomb ring finger oncogene	0.619
Smad3	MAD homolog 3 (Drosophila)	0.617	Human Rat
Bdnf	brain derived neurotrophic factor	0.616	Mouse
Il2ra	interleukin 2 receptor, alpha chain	0.614
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.614
Rara	retinoic acid receptor, alpha	0.614
Lama5	laminin, alpha 5	0.614
Ccr2	chemokine (C-C motif) receptor 2	0.612	Mouse
Myd88	myeloid differentiation primary response gene 88	0.611
Rarg	retinoic acid receptor, gamma	0.611
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.607
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.606
Rybp	RING1 and YY1 binding protein	0.606
Krt18	keratin 18	0.603
Cd6	CD6 antigen	0.602	Mouse
Gja1	gap junction protein, alpha 1	0.601
Xiap	X-linked inhibitor of apoptosis	0.600
Actn2	actinin alpha 2	0.587
Rbl2	retinoblastoma-like 2	0.580	Fly
Kit	kit oncogene	0.576
Prrx2	paired related homeobox 2	0.574
Batf	basic leucine zipper transcription factor, ATF-like	0.573
Tgfbr1	transforming growth factor, beta receptor I	0.572	Human Mouse
Fli1	Friend leukemia integration 1	0.559
Hspb8	heat shock protein 8	0.556	Mouse
Lta	lymphotoxin A	0.550	Mouse Fly
Apaf1	apoptotic peptidase activating factor 1	0.548
Prnp	prion protein	0.544
Galnt6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6	0.544
Suz12	suppressor of zeste 12 homolog (Drosophila)	0.540
Sh2d1a	SH2 domain protein 1A	0.539
Elf4	E74-like factor 4 (ets domain transcription factor)	0.536
Fgfr1	fibroblast growth factor receptor 1	0.535
Csf1	colony stimulating factor 1 (macrophage)	0.534
Ifngr1	interferon gamma receptor 1	0.534
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.528
Fshr	follicle stimulating hormone receptor	0.527
Snai2	snail homolog 2 (Drosophila)	0.524
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.515
Lmnb1	lamin B1	0.510	Mouse
Prkcd	protein kinase C, delta	0.506
Socs1	suppressor of cytokine signaling 1	0.505
Fut4	fucosyltransferase 4	0.505
Bcl3	B-cell leukemia/lymphoma 3	0.503	Human
Ccrl2	chemokine (C-C motif) receptor-like 2	0.503	Mouse
Krt13	keratin 13	0.502
Ednra	endothelin receptor type A	0.501
Lef1	lymphoid enhancer binding factor 1	0.497
Mta1	metastasis associated 1	0.497
Stat3	signal transducer and activator of transcription 3	0.494
Cul4a	cullin 4A	0.493
Ppp2ca	protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform	0.493
Acan	aggrecan	0.493
Ctnna1	catenin (cadherin associated protein), alpha 1	0.493
Bcl6	B-cell leukemia/lymphoma 6	0.493	Zebrafish
Snai1	snail homolog 1 (Drosophila)	0.489	Human Mouse
Fgf7	fibroblast growth factor 7	0.489	Mouse
Tgm2	transglutaminase 2, C polypeptide	0.488
Mapkapk2	MAP kinase-activated protein kinase 2	0.485
Mcm4	minichromosome maintenance deficient 4 homolog (S. cerevisiae)	0.485
Dlg1	discs, large homolog 1 (Drosophila)	0.483
Numb	numb gene homolog (Drosophila)	0.483
Adam17	a disintegrin and metallopeptidase domain 17	0.482
Gja3	gap junction protein, alpha 3	0.482
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.480
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.478
Chst3	carbohydrate (chondroitin 6/keratan) sulfotransferase 3	0.478
Cd3g	CD3 antigen, gamma polypeptide	0.477	Mouse
Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3	0.477
Epha2	Eph receptor A2	0.475	Human
Hif1a	hypoxia inducible factor 1, alpha subunit	0.469	Human
Cdh3	cadherin 3	0.468
Traf2	TNF receptor-associated factor 2	0.468	Human
Shh	sonic hedgehog	0.467
Tinagl1	tubulointerstitial nephritis antigen-like 1	0.459
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.458
Ryr2	ryanodine receptor 2, cardiac	0.457
Pdcd1	programmed cell death 1	0.456
Zap70	zeta-chain (TCR) associated protein kinase	0.455
Foxc1	forkhead box C1	0.455
Gata6	GATA binding protein 6	0.454
Tlr2	toll-like receptor 2	0.454
Ren1	renin 1 structural	0.454
Krt27	keratin 27	0.451	Mouse
Mecp2	methyl CpG binding protein 2	0.450
Braf	Braf transforming gene	0.450	Mouse Fly
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.450
Wnt11	wingless-related MMTV integration site 11	0.448	Mouse
Pnp2	purine-nucleoside phosphorylase 2	0.447
Coro1b	coronin, actin binding protein 1B	0.446
Maf	avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog	0.446
S100a8	S100 calcium binding protein A8 (calgranulin A)	0.446	Human
Tbx1	T-box 1	0.445
Tead4	TEA domain family member 4	0.444
Lgals7	lectin, galactose binding, soluble 7	0.442
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.442
Cst7	cystatin F (leukocystatin)	0.442
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.442	Mouse
Onecut1	one cut domain, family member 1	0.439
Nf2	neurofibromatosis 2	0.438
Tacr2	tachykinin receptor 2	0.437
Il1b	interleukin 1 beta	0.436
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.435
Bnc1	basonuclin 1	0.434
Itgav	integrin alpha V	0.433
Hspb1	heat shock protein 1	0.432
Hoxa13	homeobox A13	0.432
Ptk2	PTK2 protein tyrosine kinase 2	0.431
Lat	linker for activation of T cells	0.431
Sufu	suppressor of fused homolog (Drosophila)	0.430
Mta2	metastasis-associated gene family, member 2	0.430
Sntb1	syntrophin, basic 1	0.429
Mapk14	mitogen-activated protein kinase 14	0.428	Mouse
Ets1	E26 avian leukemia oncogene 1, 5' domain	0.427	Fly
Rasal3	RAS protein activator like 3	0.425
Hif3a	hypoxia inducible factor 3, alpha subunit	0.424
Tgfa	transforming growth factor alpha	0.424
Aff1	AF4/FMR2 family, member 1	0.422
C3	complement component 3	0.421
Zg16	zymogen granule protein 16	0.420
Mcl1	myeloid cell leukemia sequence 1	0.419
Sox9	SRY-box containing gene 9	0.419
S100a9	S100 calcium binding protein A9 (calgranulin B)	0.416	Human
Brca2	breast cancer 2	0.415
Sprr1a	small proline-rich protein 1A	0.410
Plau	plasminogen activator, urokinase	0.410	Mouse
Lmna	lamin A	0.409
Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1	0.406
Sox7	SRY-box containing gene 7	0.406
Wnt4	wingless-related MMTV integration site 4	0.405
Krt8	keratin 8	0.401
Cdh5	cadherin 5	0.398
Usp9x	ubiquitin specific peptidase 9, X chromosome	0.395
Axin1	axin 1	0.394
Trp73	transformation related protein 73	0.394
Lyz2	lysozyme 2	0.393
Yap1	yes-associated protein 1	0.392
Ezh2	enhancer of zeste homolog 2 (Drosophila)	0.392
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.391
Raf1	v-raf-leukemia viral oncogene 1	0.391
Ngf	nerve growth factor	0.391
Agxt	alanine-glyoxylate aminotransferase	0.391
Ret	ret proto-oncogene	0.391	Human
Krtap8-1	keratin associated protein 8-1	0.390
Tmpo	thymopoietin	0.389
Gfi1b	growth factor independent 1B	0.389
Wnt10b	wingless related MMTV integration site 10b	0.389	Mouse
Inhbb	inhibin beta-B	0.387
Mrc2	mannose receptor, C type 2	0.385
Myb	myeloblastosis oncogene	0.385
Il1a	interleukin 1 alpha	0.385
Ptpn2	protein tyrosine phosphatase, non-receptor type 2	0.384
Ctsl	cathepsin L	0.382
Itga3	integrin alpha 3	0.382	Mouse
Ins1	insulin I	0.381	Mouse
Ltb	lymphotoxin B	0.381
Rhog	ras homolog gene family, member G	0.381
Cdh1	cadherin 1	0.380
Ccl5	chemokine (C-C motif) ligand 5	0.379
Kitl	kit ligand	0.379
Park2	Parkinson disease (autosomal recessive, juvenile) 2, parkin	0.377
Igbp1	immunoglobulin (CD79A) binding protein 1	0.375
Selp	selectin, platelet	0.375
Aplp2	amyloid beta (A4) precursor-like protein 2	0.374
Muc5ac	mucin 5, subtypes A and C, tracheobronchial/gastric	0.374
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.374
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.373	Human
Wnt10a	wingless related MMTV integration site 10a	0.373
Zeb1	zinc finger E-box binding homeobox 1	0.372
Ptbp2	polypyrimidine tract binding protein 2	0.370
Dst	dystonin	0.368
Twist2	twist homolog 2 (Drosophila)	0.367
Creb1	cAMP responsive element binding protein 1	0.364
Bmp4	bone morphogenetic protein 4	0.364
Esr1	estrogen receptor 1 (alpha)	0.362	Mouse
Stag1	stromal antigen 1	0.360
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.358	Human
Tbx21	T-box 21	0.358
Cd14	CD14 antigen	0.357
Lrrc58	leucine rich repeat containing 58	0.356
Pthlh	parathyroid hormone-like peptide	0.355
Capn6	calpain 6	0.354
Fzd4	frizzled homolog 4 (Drosophila)	0.350
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.350
5430421N21Rik	RIKEN cDNA 5430421N21 gene	0.349
Sqstm1	sequestosome 1	0.348
Tacr1	tachykinin receptor 1	0.346
Adam10	a disintegrin and metallopeptidase domain 10	0.346
Tmem176a	transmembrane protein 176A	0.346
Sav1	salvador homolog 1 (Drosophila)	0.345
Hoxa1	homeobox A1	0.343
C3ar1	complement component 3a receptor 1	0.343
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.343
Cmklr1	chemokine-like receptor 1	0.342
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.342
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.341	Mouse Fly
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.341
C5ar1	complement component 5a receptor 1	0.340
Myo1c	myosin IC	0.340
Il10ra	interleukin 10 receptor, alpha	0.340
Ddr2	discoidin domain receptor family, member 2	0.338
Cbl	Casitas B-lineage lymphoma	0.338
Osmr	oncostatin M receptor	0.336
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.335
Prkaca	protein kinase, cAMP dependent, catalytic, alpha	0.334
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.334
Kdm6a	4lysine (K)-specific demethylase 6A	0.334
Becn1	beclin 1, autophagy related	0.333
Ncstn	nicastrin	0.332
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.331
Timm17a	translocase of inner mitochondrial membrane 17a	0.331
Tcf7	transcription factor 7, T-cell specific	0.331
Hoxb9	homeobox B9	0.331
Foxo3	forkhead box O3	0.330
Ahr	aryl-hydrocarbon receptor	0.330
Vav2	vav 2 oncogene	0.329
Max	Max protein	0.328
Cycs	cytochrome c, somatic	0.328	Mouse
Stk3	serine/threonine kinase 3 (Ste20, yeast homolog)	0.328
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.327
B2m	beta-2 microglobulin	0.326
Foxf2	forkhead box F2	0.324
Ptch2	patched homolog 2	0.323
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.322	Mouse Fly
Adora2a	adenosine A2a receptor	0.321
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.320
Pnn	pinin	0.319
Terf1	telomeric repeat binding factor 1	0.319
Fgd1	FYVE, RhoGEF and PH domain containing 1	0.319
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.318
Tubb2c	tubulin, beta 2C	0.318
Fam60a	family with sequence similarity 60, member A	0.318
Hhat	hedgehog acyltransferase	0.318
Anxa4	annexin A4	0.317
Mapk1	mitogen-activated protein kinase 1	0.317
Fadd	Fas (TNFRSF6)-associated via death domain	0.316
Lif	leukemia inhibitory factor	0.316
Flt4	FMS-like tyrosine kinase 4	0.315
Glrx3	glutaredoxin 3	0.315
Thbd	thrombomodulin	0.315
Irs1	insulin receptor substrate 1	0.314
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.314	Human
Fbn1	fibrillin 1	0.314
Ctrb1	chymotrypsinogen B1	0.313
Npr3	natriuretic peptide receptor 3	0.313
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.313
Stim2	stromal interaction molecule 2	0.312
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.311
Rhoh	ras homolog gene family, member H	0.310
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.309
Pea15a	phosphoprotein enriched in astrocytes 15A	0.308
Bak1	BCL2-antagonist/killer 1	0.308
Parp1	poly (ADP-ribose) polymerase family, member 1	0.308
Mcpt8	mast cell protease 8	0.306	Mouse
Fzd1	frizzled homolog 1 (Drosophila)	0.305
Nrk	Nik related kinase	0.304
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.304	Mouse
Mc5r	melanocortin 5 receptor	0.304
Flot1	flotillin 1	0.303
Mfn2	mitofusin 2	0.303
Pdcd6ip	programmed cell death 6 interacting protein	0.303
Fgf10	fibroblast growth factor 10	0.302
Adm	adrenomedullin	0.301
H2-Aa	histocompatibility 2, class II antigen A, alpha	0.301
Cd2	CD2 antigen	0.300
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.300
Abcc6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	0.300
Rad21	RAD21 homolog (S. pombe)	0.300
Matr3	matrin 3	0.299
Soat2	sterol O-acyltransferase 2	0.298
Entpd1	ectonucleoside triphosphate diphosphohydrolase 1	0.296
Psap	prosaposin	0.296
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.294
Omp	olfactory marker protein	0.294
Cd47	CD47 antigen (Rh-related antigen, integrin-associated signal transducer)	0.294
Pvr	poliovirus receptor	0.294
Anxa1	annexin A1	0.293
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.293
Sfrp1	secreted frizzled-related protein 1	0.293
Tnfsf8	tumor necrosis factor (ligand) superfamily, member 8	0.292
Thbs2	thrombospondin 2	0.292
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.291
Itga6	integrin alpha 6	0.291	Human Mouse
Gdf15	growth differentiation factor 15	0.291
Il27ra	interleukin 27 receptor, alpha	0.290
Fgfr2	fibroblast growth factor receptor 2	0.290	Mouse
Il18rap	interleukin 18 receptor accessory protein	0.290
Ncln	nicalin homolog (zebrafish)	0.288
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.288	Mouse
Cst3	cystatin C	0.287
Il1rl1	interleukin 1 receptor-like 1	0.287
Shc1	src homology 2 domain-containing transforming protein C1	0.287
Dlx2	distal-less homeobox 2	0.286
Cbx7	chromobox homolog 7	0.285
Tnfaip2	tumor necrosis factor, alpha-induced protein 2	0.285
Crhr1	corticotropin releasing hormone receptor 1	0.284
Rras	Harvey rat sarcoma oncogene, subgroup R	0.283	Mouse
Pkdcc	protein kinase domain containing, cytoplasmic	0.283
Morc3	microrchidia 3	0.280
Kdm2b	lysine (K)-specific demethylase 2B	0.278
Krtap12-1	keratin associated protein 12-1	0.277
Cd160	CD160 antigen	0.277
Dab1	disabled homolog 1 (Drosophila)	0.277	Mouse
Grem1	gremlin 1	0.276
Elk4	ELK4, member of ETS oncogene family	0.276
Smn1	survival motor neuron 1	0.275
Stat6	signal transducer and activator of transcription 6	0.275
Sat1	spermidine/spermine N1-acetyl transferase 1	0.274
Homer1	homer homolog 1 (Drosophila)	0.274
Masp1	mannan-binding lectin serine peptidase 1	0.272
Slc39a4	solute carrier family 39 (zinc transporter), member 4	0.272
Tnnt3	troponin T3, skeletal, fast	0.272
Sell	selectin, lymphocyte	0.271
Tspo2	translocator protein 2	0.270
Msx2	homeobox, msh-like 2	0.270
Wnt5a	wingless-related MMTV integration site 5A	0.268	Mouse
Cxcr4	chemokine (C-X-C motif) receptor 4	0.268	Mouse
Nog	noggin	0.268
Irf4	interferon regulatory factor 4	0.268
Gna15	guanine nucleotide binding protein, alpha 15	0.268
Ctsb	cathepsin B	0.266
Itga5	integrin alpha 5 (fibronectin receptor alpha)	0.266	Mouse
Smad7	MAD homolog 7 (Drosophila)	0.266
Wt1	Wilms tumor 1 homolog	0.266
Siah1b	seven in absentia 1B	0.266	Human
Setdb1	SET domain, bifurcated 1	0.265
Ahsg	alpha-2-HS-glycoprotein	0.263
Grin2a	glutamate receptor, ionotropic, NMDA2A (epsilon 1)	0.262
Prkce	protein kinase C, epsilon	0.262	Mouse
Wls	wntless homolog (Drosophila)	0.261
Cebpd	CCAAT/enhancer binding protein (C/EBP), delta	0.261
Alox12b	arachidonate 12-lipoxygenase, 12R type	0.260
Atf2	activating transcription factor 2	0.260
Xpa	xeroderma pigmentosum, complementation group A	0.260
Cxcl13	chemokine (C-X-C motif) ligand 13	0.260
Akt1	thymoma viral proto-oncogene 1	0.258
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.258
Ptch1	patched homolog 1	0.258
C1qtnf1	C1q and tumor necrosis factor related protein 1	0.258
Cenpj	centromere protein J	0.258
Mst1	macrophage stimulating 1 (hepatocyte growth factor-like)	0.258	Mouse
Src	Rous sarcoma oncogene	0.258	Human
Esr2	estrogen receptor 2 (beta)	0.257
Aff2	AF4/FMR2 family, member 2	0.255
Pfn1	profilin 1	0.254
Col11a1	collagen, type XI, alpha 1	0.253	Mouse
Phlda3	pleckstrin homology-like domain, family A, member 3	0.253
Epha4	Eph receptor A4	0.253
Epor	erythropoietin receptor	0.253
Add1	adducin 1 (alpha)	0.253
Serpina5	serine (or cysteine) peptidase inhibitor, clade A, member 5	0.252
Ctsd	cathepsin D	0.252
Pold3	polymerase (DNA-directed), delta 3, accessory subunit	0.252
Mdm4	transformed mouse 3T3 cell double minute 4	0.251
Gli2	GLI-Kruppel family member GLI2	0.251
Dhh	desert hedgehog	0.250	Mouse
Adcy4	adenylate cyclase 4	0.249
Gzmb	granzyme B	0.249
Litaf	LPS-induced TN factor	0.249
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.248
Avp	arginine vasopressin	0.248
Sfrp2	secreted frizzled-related protein 2	0.248
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.248
Birc3	baculoviral IAP repeat-containing 3	0.247
F3	coagulation factor III	0.246
Xcr1	chemokine (C motif) receptor 1	0.245	Mouse
Ccr4	chemokine (C-C motif) receptor 4	0.245	Mouse
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.244
F10	coagulation factor X	0.243
Cd3d	CD3 antigen, delta polypeptide	0.243	Mouse
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.243	Human
Id1	inhibitor of DNA binding 1	0.242
Luc7l2	LUC7-like 2 (S. cerevisiae)	0.242
Apc2	adenomatosis polyposis coli 2	0.242
Smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.242
Msln	mesothelin	0.242
Nt5e	5' nucleotidase, ecto	0.241
Tbx3	T-box 3	0.241
Serpina12	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12	0.241
Fhl3	four and a half LIM domains 3	0.241
Sgpl1	sphingosine phosphate lyase 1	0.240	Human
Meox2	mesenchyme homeobox 2	0.240
Padi3	peptidyl arginine deiminase, type III	0.239
Hnrnpu	heterogeneous nuclear ribonucleoprotein U	0.239
Ptk7	PTK7 protein tyrosine kinase 7	0.239
Usp25	ubiquitin specific peptidase 25	0.238
Fos	FBJ osteosarcoma oncogene	0.238
Ggta1	glycoprotein galactosyltransferase alpha 1, 3	0.238
Tox	thymocyte selection-associated high mobility group box	0.236
Pou3f1	POU domain, class 3, transcription factor 1	0.236
Has2	hyaluronan synthase 2	0.235
Cdc34	cell division cycle 34 homolog (S. cerevisiae)	0.235
Gpc3	glypican 3	0.234
Sptlc2	serine palmitoyltransferase, long chain base subunit 2	0.234
Tmbim1	transmembrane BAX inhibitor motif containing 1	0.234	Human
Hpcal1	hippocalcin-like 1	0.234
Bhlhe40	basic helix-loop-helix family, member e40	0.233
Fstl3	follistatin-like 3	0.233
2210010C04Rik	RIKEN cDNA 2210010C04 gene	0.233
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.233	Mouse
Eng	endoglin	0.233
Cdx2	caudal type homeobox 2	0.232
Il6	interleukin 6	0.231
Vcl	vinculin	0.231	Mouse
Ptges	prostaglandin E synthase	0.231
Ccl22	chemokine (C-C motif) ligand 22	0.230
Rel	reticuloendotheliosis oncogene	0.229	Mouse
Traf3	TNF receptor-associated factor 3	0.229
Itga2	integrin alpha 2	0.229	Mouse
Itpr2	inositol 1,4,5-triphosphate receptor 2	0.229	Mouse
Ifnar1	interferon (alpha and beta) receptor 1	0.228
Tmeff2	transmembrane protein with EGF-like and two follistatin-like domains 2	0.228
Calr	calreticulin	0.228
Capn1	calpain 1	0.228
Gata1	GATA binding protein 1	0.228	Human
Nrg1	neuregulin 1	0.227	Human
Calu	calumenin	0.227
Casp12	caspase 12	0.227
Xirp1	xin actin-binding repeat containing 1	0.226
Stc2	stanniocalcin 2	0.226
Hrc	histidine rich calcium binding protein	0.226
Atxn1	ataxin 1	0.226
Dll4	delta-like 4 (Drosophila)	0.226
Cxcl5	chemokine (C-X-C motif) ligand 5	0.226
Prlr	prolactin receptor	0.225
Gypa	glycophorin A	0.225
Fbxo47	F-box protein 47	0.225
Lyst	lysosomal trafficking regulator	0.225
Cdk2	cyclin-dependent kinase 2	0.225
Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.224
Bmp15	bone morphogenetic protein 15	0.224
Slamf1	signaling lymphocytic activation molecule family member 1	0.224
Traf3ip2	TRAF3 interacting protein 2	0.224
Klrc1	killer cell lectin-like receptor subfamily C, member 1	0.224
Arid1b	AT rich interactive domain 1B (SWI-like)	0.224
Pla2g4a	phospholipase A2, group IVA (cytosolic, calcium-dependent)	0.224
Krtap5-1	keratin associated protein 5-1	0.223
Sp3	trans-acting transcription factor 3	0.223
Il24	interleukin 24	0.223	Mouse
Treml1	triggering receptor expressed on myeloid cells-like 1	0.223
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.222
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.222
Krt19	keratin 19	0.222	Mouse
Smyd1	SET and MYND domain containing 1	0.222
Spry2	sprouty homolog 2 (Drosophila)	0.221
Hnrnpa2b1	heterogeneous nuclear ribonucleoprotein A2/B1	0.221
Tmem176b	transmembrane protein 176B	0.220
Gabpb1	GA repeat binding protein, beta 1	0.220
Chst2	carbohydrate sulfotransferase 2	0.220
Il5	interleukin 5	0.220
H2-M9	histocompatibility 2, M region locus 9	0.219
Ptgdr	prostaglandin D receptor	0.219
Fosl2	fos-like antigen 2	0.219
Lhx1	LIM homeobox protein 1	0.219
Hspa5	heat shock protein 5	0.219
Foxc2	forkhead box C2	0.219
Atr	ataxia telangiectasia and Rad3 related	0.218
Dlx3	distal-less homeobox 3	0.218
Folr4	folate receptor 4 (delta)	0.218
Chrm4	cholinergic receptor, muscarinic 4	0.217
Grn	granulin	0.217
Rnf19a	ring finger protein 19A	0.217
Gab2	growth factor receptor bound protein 2-associated protein 2	0.216
Tgfbr3	transforming growth factor, beta receptor III	0.216
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.215
Hsd17b10	hydroxysteroid (17-beta) dehydrogenase 10	0.215
Crebbp	CREB binding protein	0.215
Pdx1	pancreatic and duodenal homeobox 1	0.214
Tagln2	transgelin 2	0.214
Klf4	Kruppel-like factor 4 (gut)	0.214
Mapk9	mitogen-activated protein kinase 9	0.213
Tff1	trefoil factor 1	0.213
Insm1	insulinoma-associated 1	0.212
Orc1	origin recognition complex, subunit 1	0.212
Hnf4a	hepatic nuclear factor 4, alpha	0.212
Romo1	reactive oxygen species modulator 1	0.211
Gm10229	predicted gene 10229	0.211
Cx3cr1	chemokine (C-X3-C) receptor 1	0.211
Nr5a2	nuclear receptor subfamily 5, group A, member 2	0.211
Tnfrsf22	tumor necrosis factor receptor superfamily, member 22	0.211
Edaradd	EDAR (ectodysplasin-A receptor)-associated death domain	0.211
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.211	Fly
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.210
Krt33a	keratin 33A	0.210	Mouse
Ifngr2	interferon gamma receptor 2	0.210
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.209
Tfam	transcription factor A, mitochondrial	0.209
Krt72-ps	keratin 72, pseudogene	0.208	Mouse
Rnf112	ring finger protein 112	0.208
Gimap3	GTPase, IMAP family member 3	0.208
Gadd45a	growth arrest and DNA-damage-inducible 45 alpha	0.208
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.208
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.208
2500003M10Rik	RIKEN cDNA 2500003M10 gene	0.207
Itih1	inter-alpha trypsin inhibitor, heavy chain 1	0.207
Ndrg1	N-myc downstream regulated gene 1	0.206
Lrp2	low density lipoprotein receptor-related protein 2	0.206
Camp	cathelicidin antimicrobial peptide	0.206
Fut7	fucosyltransferase 7	0.206
Mgp	matrix Gla protein	0.206
Mybl2	myeloblastosis oncogene-like 2	0.205
Grap2	GRB2-related adaptor protein 2	0.205
Spnb2	spectrin beta 2	0.205
Iqgap3	IQ motif containing GTPase activating protein 3	0.205
Pbx1	pre B-cell leukemia transcription factor 1	0.205
Bdkrb2	bradykinin receptor, beta 2	0.204
Chad	chondroadherin	0.204
Klf6	Kruppel-like factor 6	0.204
P2ry2	purinergic receptor P2Y, G-protein coupled 2	0.203
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.203	Fly
Nod2	nucleotide-binding oligomerization domain containing 2	0.203
Plagl2	pleiomorphic adenoma gene-like 2	0.203
Cd247	CD247 antigen	0.202
Barx1	BarH-like homeobox 1	0.202
Stx1b	syntaxin 1B	0.201
Hgf	hepatocyte growth factor	0.201
L3mbtl2	l(3)mbt-like 2 (Drosophila)	0.201
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.201
Hoxd11	homeobox D11	0.201
Ch25h	cholesterol 25-hydroxylase	0.201
Tg	thyroglobulin	0.201
Prkci	protein kinase C, iota	0.201	Mouse
Itk	IL2-inducible T-cell kinase	0.200
S100a6	S100 calcium binding protein A6 (calcyclin)	0.200
Adra1a	adrenergic receptor, alpha 1a	0.200
Eif4ebp1	eukaryotic translation initiation factor 4E binding protein 1	0.200
Timp1	tissue inhibitor of metalloproteinase 1	0.200
Mmp10	matrix metallopeptidase 10	0.199
Id2	inhibitor of DNA binding 2	0.199
Apoe	apolipoprotein E	0.199
Gna11	guanine nucleotide binding protein, alpha 11	0.199
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2	0.198
Galr3	galanin receptor 3	0.198
Ube2l6	ubiquitin-conjugating enzyme E2L 6	0.198
Pgr	progesterone receptor	0.198
Edn1	endothelin 1	0.197
Fndc7	fibronectin type III domain containing 7	0.197
Hoxd8	homeobox D8	0.197
Itm2c	integral membrane protein 2C	0.196
Dkc1	dyskeratosis congenita 1, dyskerin homolog (human)	0.196
Tfdp2	transcription factor Dp 2	0.196	Fly
Lox	lysyl oxidase	0.195
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.195
Usp42	ubiquitin specific peptidase 42	0.194
Cel	carboxyl ester lipase	0.194
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.194
Akr1a4	aldo-keto reductase family 1, member A4 (aldehyde reductase)	0.194
Sdc1	syndecan 1	0.193
Pmpcb	peptidase (mitochondrial processing) beta	0.193
Srms	src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites	0.193
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.193
Eln	elastin	0.192
E2f3	E2F transcription factor 3	0.192	Mouse
Mst1r	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)	0.192
Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like	0.192
Efna4	ephrin A4	0.192
Cxcr5	chemokine (C-X-C motif) receptor 5	0.191	Mouse
Kctd11	potassium channel tetramerisation domain containing 11	0.191
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.191
Ptafr	platelet-activating factor receptor	0.191
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.191
Plcd1	phospholipase C, delta 1	0.190
Slurp1	secreted Ly6/Plaur domain containing 1	0.190
P4ha2	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide	0.190
Ptgfrn	prostaglandin F2 receptor negative regulator	0.190
Cd9	CD9 antigen	0.189
Pax2	paired box gene 2	0.189
Mvp	major vault protein	0.189
Agtr1a	angiotensin II receptor, type 1a	0.189	Mouse
St8sia5	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5	0.189
Il7	interleukin 7	0.189
Cdk6	cyclin-dependent kinase 6	0.188
Polb	polymerase (DNA directed), beta	0.188
Lin9	lin-9 homolog (C. elegans)	0.187
Polr2a	polymerase (RNA) II (DNA directed) polypeptide A	0.187
Rnf41	ring finger protein 41	0.187	Human
Gsdma3	gasdermin A3	0.187
Trak2	trafficking protein, kinesin binding 2	0.187
F2	coagulation factor II	0.186
Adipor1	adiponectin receptor 1	0.186
Fgd3	FYVE, RhoGEF and PH domain containing 3	0.185
Atp11c	ATPase, class VI, type 11C	0.185
Hbb-b1	hemoglobin, beta adult major chain	0.185
Map3k5	mitogen-activated protein kinase kinase kinase 5	0.185
Ahnak	AHNAK nucleoprotein (desmoyokin)	0.185
Cd81	CD81 antigen	0.185
Sct	secretin	0.184
Xcl1	chemokine (C motif) ligand 1	0.184
Dapk2	death-associated protein kinase 2	0.184
Cfh	complement component factor h	0.183
Twist1	twist homolog 1 (Drosophila)	0.183
Nkx3-1	NK-3 transcription factor, locus 1 (Drosophila)	0.182	Human
Trim47	tripartite motif-containing 47	0.182
Stat1	signal transducer and activator of transcription 1	0.182
Apoa1	apolipoprotein A-I	0.182
Pik3c3	phosphoinositide-3-kinase, class 3	0.182
Cd38	CD38 antigen	0.182
Nphs2	nephrosis 2 homolog, podocin (human)	0.182
Alx3	aristaless-like homeobox 3	0.181
Tlr6	toll-like receptor 6	0.181
S1pr2	sphingosine-1-phosphate receptor 2	0.181
Alox15	arachidonate 15-lipoxygenase	0.181
Hbegf	heparin-binding EGF-like growth factor	0.181
Il22	interleukin 22	0.181	Mouse
Bag6	BCL2-associated athanogene 6	0.181
Pkp1	plakophilin 1	0.180
Tap1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.180
Fbn2	fibrillin 2	0.179
Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.179
Prrx1	paired related homeobox 1	0.179
Srsf1	serine/arginine-rich splicing factor 1	0.179
Gbp5	guanylate binding protein 5	0.179
Egfr	epidermal growth factor receptor	0.179	Fly
Slc25a48	solute carrier family 25, member 48	0.179
St3gal1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	0.179
Cyp2d10	cytochrome P450, family 2, subfamily d, polypeptide 10	0.179	Mouse
Msh6	mutS homolog 6 (E. coli)	0.179
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.178
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.178
Gnb2	guanine nucleotide binding protein (G protein), beta 2	0.178
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.178
Myod1	myogenic differentiation 1	0.178
Krt84	keratin 84	0.177	Mouse
Dll1	delta-like 1 (Drosophila)	0.176
Map2k3	mitogen-activated protein kinase kinase 3	0.176