IMP: Integrative Multi-species Prediction

Mus musculus

0 genes annotated in mouse

muscular dystrophy

DOID:9884

A myopathy is characterized by progressive skeletal muscle weakness degeneration.

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Gene Predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "muscular dystrophy" (in gray)

Name	Description	Probability	Func Analog Organism
Dmd	dystrophin, muscular dystrophy	0.999	Human
Col1a1	collagen, type I, alpha 1	0.970
Sgcg	sarcoglycan, gamma (dystrophin-associated glycoprotein)	0.867
Col4a1	collagen, type IV, alpha 1	0.846
Sgca	sarcoglycan, alpha (dystrophin-associated glycoprotein)	0.828
Cav3	caveolin 3	0.778
Ldb3	LIM domain binding 3	0.758
Col3a1	collagen, type III, alpha 1	0.751
Ttn	titin	0.717
Des	desmin	0.712
Dag1	dystroglycan 1	0.688	Human
Col6a2	collagen, type VI, alpha 2	0.688	Human
Col1a2	collagen, type I, alpha 2	0.674
Col5a1	collagen, type V, alpha 1	0.614
Col6a1	collagen, type VI, alpha 1	0.602	Human
Col6a3	collagen, type VI, alpha 3	0.582	Human
Nrap	nebulin-related anchoring protein	0.558
Snta1	syntrophin, acidic 1	0.556
Large	like-glycosyltransferase	0.547
Hnrnpd	heterogeneous nuclear ribonucleoprotein D	0.448
Actn2	actinin alpha 2	0.432
Col4a2	collagen, type IV, alpha 2	0.390
Col5a2	collagen, type V, alpha 2	0.377
Fktn	fukutin	0.351
Bgn	biglycan	0.292
Fkrp	fukutin related protein	0.271
Lmna	lamin A	0.253	Human
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.245
Pygm	muscle glycogen phosphorylase	0.234
Cox6a2	cytochrome c oxidase, subunit VI a, polypeptide 2	0.215
Casq1	calsequestrin 1	0.212
Anxa1	annexin A1	0.212
Itga7	integrin alpha 7	0.211	Human
Hnrnpa2b1	heterogeneous nuclear ribonucleoprotein A2/B1	0.204
Hrc	histidine rich calcium binding protein	0.187
Col15a1	collagen, type XV, alpha 1	0.187
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.165
Pdlim3	PDZ and LIM domain 3	0.154
Eln	elastin	0.132
Smn1	survival motor neuron 1	0.130
Dmpk	dystrophia myotonica-protein kinase	0.124	Human
Fbn1	fibrillin 1	0.119
Mstn	myostatin	0.114
Eif2c1	eukaryotic translation initiation factor 2C, 1	0.113
Hspb7	heat shock protein family, member 7 (cardiovascular)	0.112
Xirp1	xin actin-binding repeat containing 1	0.108
Dtna	dystrobrevin alpha	0.105
Art1	ADP-ribosyltransferase 1	0.103
Mfap5	microfibrillar associated protein 5	0.102
Srpk3	serine/arginine-rich protein specific kinase 3	0.098
Myom1	myomesin 1	0.098
Dysf	dysferlin	0.096	Human
Gja1	gap junction protein, alpha 1	0.090
Tnxb	tenascin XB	0.089
Ckm	creatine kinase, muscle	0.087
Adamts2	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2	0.086
Anxa2	annexin A2	0.086
Ltbp4	latent transforming growth factor beta binding protein 4	0.079
Col16a1	collagen, type XVI, alpha 1	0.077
B3gnt1	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1	0.075
Dnajb5	DnaJ (Hsp40) homolog, subfamily B, member 5	0.074
Mmp2	matrix metallopeptidase 2	0.067
Atp1a2	ATPase, Na+/K+ transporting, alpha 2 polypeptide	0.066
Lama4	laminin, alpha 4	0.066
Plec	plectin	0.064	Human
Tnnc1	troponin C, cardiac/slow skeletal	0.063
Yipf7	Yip1 domain family, member 7	0.061
Sparcl1	SPARC-like 1	0.060
Tnks1bp1	tankyrase 1 binding protein 1	0.060
Tnnt2	troponin T2, cardiac	0.059
Fbln2	fibulin 2	0.059
Postn	periostin, osteoblast specific factor	0.058
Hspb2	heat shock protein 2	0.056
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.056
Myom2	myomesin 2	0.054
Casq2	calsequestrin 2	0.053
Ankrd1	ankyrin repeat domain 1 (cardiac muscle)	0.053
Nphp1	nephronophthisis 1 (juvenile) homolog (human)	0.052
Ighmbp2	immunoglobulin mu binding protein 2	0.052
Slc35b1	solute carrier family 35, member B1	0.051
Hspb8	heat shock protein 8	0.050
Sparc	secreted acidic cysteine rich glycoprotein	0.050
Pcolce	procollagen C-endopeptidase enhancer protein	0.048
Phkg1	phosphorylase kinase gamma 1	0.046
Aoc3	amine oxidase, copper containing 3	0.046
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.046
Mterfd1	MTERF domain containing 1	0.045
Lamb2	laminin, beta 2	0.045
Nos3	nitric oxide synthase 3, endothelial cell	0.045
Col14a1	collagen, type XIV, alpha 1	0.044
Dpt	dermatopontin	0.044
Sspn	sarcospan	0.043
Myl1	myosin, light polypeptide 1	0.041
Zfp651	zinc finger protein 651	0.041
Col8a1	collagen, type VIII, alpha 1	0.040
Tgfb1i1	transforming growth factor beta 1 induced transcript 1	0.040
Cav1	caveolin 1, caveolae protein	0.040
Cspg4	chondroitin sulfate proteoglycan 4	0.039
Kdelr3	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3	0.039
2310046A06Rik	RIKEN cDNA 2310046A06 gene	0.039
Hnrnpa1	heterogeneous nuclear ribonucleoprotein A1	0.038
Tnnt3	troponin T3, skeletal, fast	0.038
Svep1	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1	0.038
Mfap4	microfibrillar-associated protein 4	0.037
Csrp3	cysteine and glycine-rich protein 3	0.036
Figf	c-fos induced growth factor	0.035
Myl3	myosin, light polypeptide 3	0.035
Cdh13	cadherin 13	0.034
Ryr1	ryanodine receptor 1, skeletal muscle	0.034
Popdc3	popeye domain containing 3	0.034
Sh3pxd2b	SH3 and PX domains 2B	0.033
Srsf6	serine/arginine-rich splicing factor 6	0.033
Ptrf	polymerase I and transcript release factor	0.032
Acta1	actin, alpha 1, skeletal muscle	0.032
Creb3l1	cAMP responsive element binding protein 3-like 1	0.031
Myf5	myogenic factor 5	0.031
P2ry2	purinergic receptor P2Y, G-protein coupled 2	0.031
Sdc4	syndecan 4	0.031
Mgp	matrix Gla protein	0.030
Myo18a	myosin XVIIIA	0.030
Cd248	CD248 antigen, endosialin	0.030
C1qtnf6	C1q and tumor necrosis factor related protein 6	0.029
Tpm2	tropomyosin 2, beta	0.029
Ank	progressive ankylosis	0.029
Loxl1	lysyl oxidase-like 1	0.028
Ctsk	cathepsin K	0.028
Mrgprf	MAS-related GPR, member F	0.028
S100a6	S100 calcium binding protein A6 (calcyclin)	0.028
Sgcd	sarcoglycan, delta (dystrophin-associated glycoprotein)	0.028	Human
Myh1	myosin, heavy polypeptide 1, skeletal muscle, adult	0.028
Pkia	protein kinase inhibitor, alpha	0.028
Phka1	phosphorylase kinase alpha 1	0.028
Myoz2	myozenin 2	0.027
Nid1	nidogen 1	0.027
Idua	iduronidase, alpha-L-	0.027
Sec61a1	Sec61 alpha 1 subunit (S. cerevisiae)	0.027
Cisd2	CDGSH iron sulfur domain 2	0.027
Alpk3	alpha-kinase 3	0.027
Pgam2	phosphoglycerate mutase 2	0.026
Islr	immunoglobulin superfamily containing leucine-rich repeat	0.026
Rps6ka4	ribosomal protein S6 kinase, polypeptide 4	0.026
Lama2	laminin, alpha 2	0.026	Human
Aebp1	AE binding protein 1	0.026
Prkcdbp	protein kinase C, delta binding protein	0.026
Bag3	BCL2-associated athanogene 3	0.026
Utrn	utrophin	0.026
Sgcz	sarcoglycan zeta	0.025
Fap	fibroblast activation protein	0.025
Plin4	perilipin 4	0.024
Slc6a8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8	0.024
Igfbp6	insulin-like growth factor binding protein 6	0.024
Chpf	chondroitin polymerizing factor	0.024
Ppp2ca	protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform	0.024
Myo1c	myosin IC	0.024
Angptl2	angiopoietin-like 2	0.024
Tns1	tensin 1	0.023
Flnc	filamin C, gamma	0.022	Human
Ewsr1	Ewing sarcoma breakpoint region 1	0.022
Creld2	cysteine-rich with EGF-like domains 2	0.022
Igfbp5	insulin-like growth factor binding protein 5	0.021
Bmp1	bone morphogenetic protein 1	0.021
6330577E15Rik	RIKEN cDNA 6330577E15 gene	0.021
Thbs2	thrombospondin 2	0.020
Dot1l	DOT1-like, histone H3 methyltransferase (S. cerevisiae)	0.020
Prkrir	protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)	0.020
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.020
Phlda3	pleckstrin homology-like domain, family A, member 3	0.020
Akap12	A kinase (PRKA) anchor protein (gravin) 12	0.020
Scn1b	sodium channel, voltage-gated, type I, beta	0.020
Samd4	sterile alpha motif domain containing 4	0.020
Kif1c	kinesin family member 1C	0.020
Murc	muscle-related coiled-coil protein	0.020
Mef2d	myocyte enhancer factor 2D	0.019
Sgcb	sarcoglycan, beta (dystrophin-associated glycoprotein)	0.019	Human
Egflam	EGF-like, fibronectin type III and laminin G domains	0.019
Fibin	fin bud initiation factor homolog (zebrafish)	0.019
Larp4b	La ribonucleoprotein domain family, member 4B	0.019
Slc39a13	solute carrier family 39 (metal ion transporter), member 13	0.019
Itgb1bp2	integrin beta 1 binding protein 2	0.019
Ckmt2	creatine kinase, mitochondrial 2	0.019
Ehbp1l1	EH domain binding protein 1-like 1	0.019
Trim47	tripartite motif-containing 47	0.019
Gm10393	predicted gene 10393	0.018
Trim54	tripartite motif-containing 54	0.018
Lynx1	Ly6/neurotoxin 1	0.018
Txlnb	taxilin beta	0.018
Ptprm	protein tyrosine phosphatase, receptor type, M	0.018
Entpd2	ectonucleoside triphosphate diphosphohydrolase 2	0.018
Fndc1	fibronectin type III domain containing 1	0.018
Iqcc	IQ motif containing C	0.018
Lmod2	leiomodin 2 (cardiac)	0.018
Dsc3	desmocollin 3	0.017
Mical2	microtubule associated monoxygenase, calponin and LIM domain containing 2	0.017
Hnrnpk	heterogeneous nuclear ribonucleoprotein K	0.017
Atp2a1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.017
Fbxo32	F-box protein 32	0.017
Phldb1	pleckstrin homology-like domain, family B, member 1	0.017
Tnni1	troponin I, skeletal, slow 1	0.017
Nfe2l1	nuclear factor, erythroid derived 2,-like 1	0.017
Tnnt1	troponin T1, skeletal, slow	0.017
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.017
Marveld1	MARVEL (membrane-associating) domain containing 1	0.017
Pfkfb1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	0.016
Tnnc2	troponin C2, fast	0.016
Tnfrsf12a	tumor necrosis factor receptor superfamily, member 12a	0.016
Apobec2	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2	0.016
Cul1	cullin 1	0.016
Popdc2	popeye domain containing 2	0.016
Ahnak	AHNAK nucleoprotein (desmoyokin)	0.016
Atf1	activating transcription factor 1	0.016
Nfic	nuclear factor I/C	0.016
Eef1a2	eukaryotic translation elongation factor 1 alpha 2	0.016
Mmp23	matrix metallopeptidase 23	0.016
Eif2a	eukaryotic translation initiation factor 2A	0.016
Cuedc1	CUE domain containing 1	0.016
Mybpc3	myosin binding protein C, cardiac	0.016
Naalad2	N-acetylated alpha-linked acidic dipeptidase 2	0.016
Bves	blood vessel epicardial substance	0.016
Ankrd28	ankyrin repeat domain 28	0.016
Limch1	LIM and calponin homology domains 1	0.016
Ogn	osteoglycin	0.016
Hspb3	heat shock protein 3	0.016
Ucp3	uncoupling protein 3 (mitochondrial, proton carrier)	0.015
Tnc	tenascin C	0.015
Cilp	cartilage intermediate layer protein, nucleotide pyrophosphohydrolase	0.015
Phtf2	putative homeodomain transcription factor 2	0.015
Manf	mesencephalic astrocyte-derived neurotrophic factor	0.015
Abcc9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	0.015
Ptprb	protein tyrosine phosphatase, receptor type, B	0.015
Pdia6	protein disulfide isomerase associated 6	0.015
Zfp639	zinc finger protein 639	0.015
Mtap4	microtubule-associated protein 4	0.015
Actc1	actin, alpha, cardiac muscle 1	0.015
Art3	ADP-ribosyltransferase 3	0.015
Smpx	small muscle protein, X-linked	0.015
Lamc1	laminin, gamma 1	0.015
Usp13	ubiquitin specific peptidase 13 (isopeptidase T-3)	0.015
Dnajb11	DnaJ (Hsp40) homolog, subfamily B, member 11	0.015
D17Wsu104e	DNA segment, Chr 17, Wayne State University 104, expressed	0.015
Copz2	coatomer protein complex, subunit zeta 2	0.015
Ppp1r3c	protein phosphatase 1, regulatory (inhibitor) subunit 3C	0.014
Tmem45a	transmembrane protein 45a	0.014
Pde4dip	phosphodiesterase 4D interacting protein (myomegalin)	0.014
Hnrnpa0	heterogeneous nuclear ribonucleoprotein A0	0.014
Ccdc80	coiled-coil domain containing 80	0.014
Ptbp2	polypyrimidine tract binding protein 2	0.014
Sod1	superoxide dismutase 1, soluble	0.014
Parm1	prostate androgen-regulated mucin-like protein 1	0.014
Rhbdf1	rhomboid family 1 (Drosophila)	0.014
Pfn2	profilin 2	0.014
Notch3	Notch gene homolog 3 (Drosophila)	0.014
Hnrnph3	heterogeneous nuclear ribonucleoprotein H3	0.014
Hnrnpa3	heterogeneous nuclear ribonucleoprotein A3	0.014
Cfl2	cofilin 2, muscle	0.014
Tnni2	troponin I, skeletal, fast 2	0.014
Htra3	HtrA serine peptidase 3	0.014
Egfr	epidermal growth factor receptor	0.014
Dnaja2	DnaJ (Hsp40) homolog, subfamily A, member 2	0.014
Clec11a	C-type lectin domain family 11, member a	0.014
Tenc1	tensin like C1 domain-containing phosphatase	0.014
Ddr2	discoidin domain receptor family, member 2	0.014
Synpo2	synaptopodin 2	0.014
Mpdz	multiple PDZ domain protein	0.014
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.014
Sun1	Sad1 and UNC84 domain containing 1	0.014
Slc12a4	solute carrier family 12, member 4	0.014
Jup	junction plakoglobin	0.014
Chrnb1	cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)	0.013
Ndrg2	N-myc downstream regulated gene 2	0.013
Svil	supervillin	0.013
Tmem208	transmembrane protein 208	0.013
Hfe2	hemochromatosis type 2 (juvenile) (human homolog)	0.013
Htra1	HtrA serine peptidase 1	0.013
Anxa11	annexin A11	0.013
Eif5	eukaryotic translation initiation factor 5	0.013
Pvalb	parvalbumin	0.013
Ifrd1	interferon-related developmental regulator 1	0.013
Gpr133	G protein-coupled receptor 133	0.013
Lamb1	laminin B1	0.013
Gys1	glycogen synthase 1, muscle	0.013
Tcea3	transcription elongation factor A (SII), 3	0.013
Pfdn2	prefoldin 2	0.013
Olfml2b	olfactomedin-like 2B	0.013
Fstl1	follistatin-like 1	0.013
Krt81	keratin 81	0.013
1110067D22Rik	RIKEN cDNA 1110067D22 gene	0.013
Jph2	junctophilin 2	0.013
Ski	ski sarcoma viral oncogene homolog (avian)	0.013
Eif1	eukaryotic translation initiation factor 1	0.013
Mylpf	myosin light chain, phosphorylatable, fast skeletal muscle	0.013
Myoz1	myozenin 1	0.013
Heyl	hairy/enhancer-of-split related with YRPW motif-like	0.013
Srprb	signal recognition particle receptor, B subunit	0.013
Fmod	fibromodulin	0.013
Sh3bgr	SH3-binding domain glutamic acid-rich protein	0.013
Sntb1	syntrophin, basic 1	0.013
A430110N23Rik	RIKEN cDNA A430110N23 gene	0.012
Cmya5	cardiomyopathy associated 5	0.012
Igfbp7	insulin-like growth factor binding protein 7	0.012
Nr1d1	nuclear receptor subfamily 1, group D, member 1	0.012
Myh11	myosin, heavy polypeptide 11, smooth muscle	0.012
Gas6	growth arrest specific 6	0.012
Srpx2	sushi-repeat-containing protein, X-linked 2	0.012
Lmcd1	LIM and cysteine-rich domains 1	0.012
Tgfb3	transforming growth factor, beta 3	0.012
Supv3l1	suppressor of var1, 3-like 1 (S. cerevisiae)	0.012
Ptk2	PTK2 protein tyrosine kinase 2	0.012
Ddx5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	0.012
Ltbr	lymphotoxin B receptor	0.012
Loxl3	lysyl oxidase-like 3	0.012
Akt1	thymoma viral proto-oncogene 1	0.012
Hdac2	histone deacetylase 2	0.012
Hhatl	hedgehog acyltransferase-like	0.012
Mtor	mechanistic target of rapamycin (serine/threonine kinase)	0.012
Kremen1	kringle containing transmembrane protein 1	0.012
Nae1	NEDD8 activating enzyme E1 subunit 1	0.012
Pcmt1	protein-L-isoaspartate (D-aspartate) O-methyltransferase 1	0.012
Slc27a1	solute carrier family 27 (fatty acid transporter), member 1	0.012
Pbxip1	pre-B-cell leukemia transcription factor interacting protein 1	0.012
Cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	0.012
Extl2	exostoses (multiple)-like 2	0.012
Kank2	KN motif and ankyrin repeat domains 2	0.012
Mtap7d1	microtubule-associated protein 7 domain containing 1	0.012
Map2k3	mitogen-activated protein kinase kinase 3	0.012
Myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.012
Sorbs1	sorbin and SH3 domain containing 1	0.011
Rabggtb	RAB geranylgeranyl transferase, b subunit	0.011
Fgfr2	fibroblast growth factor receptor 2	0.011
Paip2b	poly(A) binding protein interacting protein 2B	0.011
Cap2	CAP, adenylate cyclase-associated protein, 2 (yeast)	0.011
Lum	lumican	0.011
Ryr2	ryanodine receptor 2, cardiac	0.011
Dusp1	dual specificity phosphatase 1	0.011
Fhod3	formin homology 2 domain containing 3	0.011
Hdac4	histone deacetylase 4	0.011
Krr1	KRR1, small subunit (SSU) processome component, homolog (yeast)	0.011
Steap3	STEAP family member 3	0.011
Srsf11	serine/arginine-rich splicing factor 11	0.011
Sdf2l1	stromal cell-derived factor 2-like 1	0.011
Smoc2	SPARC related modular calcium binding 2	0.011
Gtf2ird1	general transcription factor II I repeat domain-containing 1	0.011
Slc24a3	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3	0.011
Arhgap21	Rho GTPase activating protein 21	0.011
Speg	SPEG complex locus	0.011
Sync	syncoilin	0.011
Aox1	aldehyde oxidase 1	0.011
Scara3	scavenger receptor class A, member 3	0.011
Ptpn21	protein tyrosine phosphatase, non-receptor type 21	0.011
Cox8b	cytochrome c oxidase, subunit VIIIb	0.011
Srp9	signal recognition particle 9	0.011
Hspa9	heat shock protein 9	0.010
Serpinh1	serine (or cysteine) peptidase inhibitor, clade H, member 1	0.010
Sorbs3	sorbin and SH3 domain containing 3	0.010
Lox	lysyl oxidase	0.010
Cacna1s	calcium channel, voltage-dependent, L type, alpha 1S subunit	0.010
Myh3	myosin, heavy polypeptide 3, skeletal muscle, embryonic	0.010
C2cd2	C2 calcium-dependent domain containing 2	0.010
Adk	adenosine kinase	0.010
Prkce	protein kinase C, epsilon	0.010
Sod3	superoxide dismutase 3, extracellular	0.010
Prelp	proline arginine-rich end leucine-rich repeat	0.010
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.010
Rasl12	RAS-like, family 12	0.010
Pmepa1	prostate transmembrane protein, androgen induced 1	0.010
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.010
Ik	IK cytokine	0.010
Srsf5	serine/arginine-rich splicing factor 5	0.010
Tnni3	troponin I, cardiac 3	0.010
Ncl	nucleolin	0.010
AI597479	expressed sequence AI597479	0.010