Process View
0 genes annotated in mouse
DOID:1826
A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.
In addition to gene-name show these genes:
Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.
Name | Description | Probability | Func Analog Organism | |
---|---|---|---|---|
Dlg4 | discs, large homolog 4 (Drosophila) | 0.836 | ||
Stx1a | syntaxin 1A (brain) | 0.351 | ||
Grin1 | glutamate receptor, ionotropic, NMDA1 (zeta 1) | 0.344 | ||
Htt | huntingtin | 0.304 | ||
Grin2b | glutamate receptor, ionotropic, NMDA2B (epsilon 2) | 0.251 | ||
Ywhab | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | 0.211 | ||
Camk2a | calcium/calmodulin-dependent protein kinase II alpha | 0.209 | ||
Gba | glucosidase, beta, acid | 0.196 | ||
S100a11 | S100 calcium binding protein A11 (calgizzarin) | 0.161 | ||
Atp6v0e | ATPase, H+ transporting, lysosomal V0 subunit E | 0.145 | ||
Inadl | InaD-like (Drosophila) | 0.133 | ||
Dync1h1 | dynein cytoplasmic 1 heavy chain 1 | 0.113 | ||
Emx1 | empty spiracles homolog 1 (Drosophila) | 0.110 | ||
App | amyloid beta (A4) precursor protein | 0.099 | ||
Arpc3 | actin related protein 2/3 complex, subunit 3 | 0.096 | ||
Npc2 | Niemann Pick type C2 | 0.093 | ||
Dlgap1 | discs, large (Drosophila) homolog-associated protein 1 | 0.091 | ||
Gria2 | glutamate receptor, ionotropic, AMPA2 (alpha 2) | 0.087 | ||
Spnb2 | spectrin beta 2 | 0.079 | ||
Ywhaz | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.079 | ||
Sstr4 | somatostatin receptor 4 | 0.071 | ||
Grn | granulin | 0.068 | ||
Slc34a3 | solute carrier family 34 (sodium phosphate), member 3 | 0.067 | ||
Sat1 | spermidine/spermine N1-acetyl transferase 1 | 0.066 | ||
Kcnc3 | potassium voltage gated channel, Shaw-related subfamily, member 3 | 0.066 | ||
Fgf23 | fibroblast growth factor 23 | 0.064 | ||
Cacna1c | calcium channel, voltage-dependent, L type, alpha 1C subunit | 0.060 | ||
Dlg2 | discs, large homolog 2 (Drosophila) | 0.059 | ||
Txndc17 | thioredoxin domain containing 17 | 0.059 | ||
Cacna2d1 | calcium channel, voltage-dependent, alpha2/delta subunit 1 | 0.056 | ||
Gria1 | glutamate receptor, ionotropic, AMPA1 (alpha 1) | 0.055 | ||
Grin2c | glutamate receptor, ionotropic, NMDA2C (epsilon 3) | 0.049 | ||
Ppp2r1a | protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform | 0.047 | ||
Rnh1 | ribonuclease/angiogenin inhibitor 1 | 0.046 | ||
Dennd5a | DENN/MADD domain containing 5A | 0.046 | ||
Prkce | protein kinase C, epsilon | 0.045 | ||
Kl | klotho | 0.044 | ||
Nedd4l | neural precursor cell expressed, developmentally down-regulated gene 4-like | 0.044 | ||
S100a6 | S100 calcium binding protein A6 (calcyclin) | 0.043 | ||
Rasgrf2 | RAS protein-specific guanine nucleotide-releasing factor 2 | 0.043 | ||
Ntrk2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.040 | ||
Litaf | LPS-induced TN factor | 0.040 | ||
Slc12a6 | solute carrier family 12, member 6 | 0.038 | ||
Cd46 | CD46 antigen, complement regulatory protein | 0.038 | ||
Lamp2 | lysosomal-associated membrane protein 2 | 0.037 | ||
Apln | apelin | 0.036 | ||
Atp1b2 | ATPase, Na+/K+ transporting, beta 2 polypeptide | 0.034 | ||
Ctsz | cathepsin Z | 0.034 | ||
Prkcc | protein kinase C, gamma | 0.033 | ||
Mark4 | MAP/microtubule affinity-regulating kinase 4 | 0.033 | ||
Napb | N-ethylmaleimide sensitive fusion protein attachment protein beta | 0.033 | ||
Vamp2 | vesicle-associated membrane protein 2 | 0.032 | ||
Plcg1 | phospholipase C, gamma 1 | 0.032 | ||
Eno1 | enolase 1, alpha non-neuron | 0.031 | ||
Npcd | neuronal pentraxin chromo domain | 0.031 | ||
Dnm1 | dynamin 1 | 0.030 | ||
Adamts1 | a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 | 0.029 | ||
Lgals3 | lectin, galactose binding, soluble 3 | 0.027 | ||
Thrb | thyroid hormone receptor beta | 0.027 | ||
Ctsb | cathepsin B | 0.027 | ||
Pde4a | phosphodiesterase 4A, cAMP specific | 0.026 | ||
Tbca | tubulin cofactor A | 0.026 | ||
Gjb2 | gap junction protein, beta 2 | 0.025 | ||
Kcnj10 | potassium inwardly-rectifying channel, subfamily J, member 10 | 0.025 | ||
Klc2 | kinesin light chain 2 | 0.025 | ||
Zfp865 | zinc finger protein 865 | 0.025 | ||
Dctn1 | dynactin 1 | 0.024 | ||
Ptprm | protein tyrosine phosphatase, receptor type, M | 0.024 | ||
Gfra2 | glial cell line derived neurotrophic factor family receptor alpha 2 | 0.024 | ||
Dtna | dystrobrevin alpha | 0.023 | ||
Adam4 | a disintegrin and metallopeptidase domain 4 | 0.023 | ||
Kcna2 | potassium voltage-gated channel, shaker-related subfamily, member 2 | 0.023 | ||
Btrc | beta-transducin repeat containing protein | 0.022 | ||
Arl6 | ADP-ribosylation factor-like 6 | 0.022 | ||
Rpgrip1l | Rpgrip1-like | 0.022 | ||
Kcnb1 | potassium voltage gated channel, Shab-related subfamily, member 1 | 0.022 | ||
Pdcd6 | programmed cell death 6 | 0.022 | ||
Ppp3r1 | protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) | 0.022 | ||
Scn1b | sodium channel, voltage-gated, type I, beta | 0.021 | ||
Kcnma1 | potassium large conductance calcium-activated channel, subfamily M, alpha member 1 | 0.021 | ||
Slc1a2 | solute carrier family 1 (glial high affinity glutamate transporter), member 2 | 0.021 | ||
Hsd3b7 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | 0.021 | ||
Inpp5j | inositol polyphosphate 5-phosphatase J | 0.021 | ||
Rragc | Ras-related GTP binding C | 0.021 | ||
Cacng2 | calcium channel, voltage-dependent, gamma subunit 2 | 0.021 | ||
Cttn | cortactin | 0.020 | ||
Vamp8 | vesicle-associated membrane protein 8 | 0.020 | ||
Kalrn | kalirin, RhoGEF kinase | 0.020 | ||
Vdr | vitamin D receptor | 0.020 | ||
Sema6a | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.020 | ||
Ap2a1 | adaptor protein complex AP-2, alpha 1 subunit | 0.020 | ||
Atxn1 | ataxin 1 | 0.019 | ||
Agpat1 | 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) | 0.019 | ||
Snap25 | synaptosomal-associated protein 25 | 0.019 | ||
Unc5c | unc-5 homolog C (C. elegans) | 0.019 | ||
Syn2 | synapsin II | 0.019 | ||
Zfp444 | zinc finger protein 444 | 0.019 | ||
Elk1 | ELK1, member of ETS oncogene family | 0.019 | ||
Sema6c | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C | 0.018 | ||
Sstr1 | somatostatin receptor 1 | 0.018 | ||
Cplx2 | complexin 2 | 0.018 | ||
Park2 | Parkinson disease (autosomal recessive, juvenile) 2, parkin | 0.018 | ||
Kcna4 | potassium voltage-gated channel, shaker-related subfamily, member 4 | 0.018 | ||
Large | like-glycosyltransferase | 0.017 | ||
Nrxn1 | neurexin I | 0.017 | ||
Snrk | SNF related kinase | 0.017 | ||
Dvl3 | dishevelled 3, dsh homolog (Drosophila) | 0.017 | ||
Macf1 | microtubule-actin crosslinking factor 1 | 0.017 | ||
Lin7b | lin-7 homolog B (C. elegans) | 0.017 | ||
Cux2 | cut-like homeobox 2 | 0.017 | ||
Shc3 | src homology 2 domain-containing transforming protein C3 | 0.017 | ||
S100a10 | S100 calcium binding protein A10 (calpactin) | 0.017 | ||
Clic1 | chloride intracellular channel 1 | 0.017 | ||
Myh10 | myosin, heavy polypeptide 10, non-muscle | 0.017 | ||
Hspa12a | heat shock protein 12A | 0.016 | ||
Sgcd | sarcoglycan, delta (dystrophin-associated glycoprotein) | 0.016 | ||
Sema6d | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D | 0.016 | ||
Adam22 | a disintegrin and metallopeptidase domain 22 | 0.016 | ||
Pxdn | peroxidasin homolog (Drosophila) | 0.016 | ||
Kifap3 | kinesin-associated protein 3 | 0.016 | ||
Syt7 | synaptotagmin VII | 0.016 | ||
Asah1 | N-acylsphingosine amidohydrolase 1 | 0.016 | ||
Gns | glucosamine (N-acetyl)-6-sulfatase | 0.016 | ||
Apbb2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.016 | ||
Sgip1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.016 | ||
Lrrc23 | leucine rich repeat containing 23 | 0.016 | ||
Chrm1 | cholinergic receptor, muscarinic 1, CNS | 0.016 | ||
Ryr2 | ryanodine receptor 2, cardiac | 0.016 | ||
Kcnk3 | potassium channel, subfamily K, member 3 | 0.016 | ||
Rab3a | RAB3A, member RAS oncogene family | 0.016 | ||
Adcyap1r1 | adenylate cyclase activating polypeptide 1 receptor 1 | 0.016 | ||
Syt1 | synaptotagmin I | 0.016 | ||
Ftl1 | ferritin light chain 1 | 0.016 | ||
Tigd5 | tigger transposable element derived 5 | 0.015 | ||
Kcnj4 | potassium inwardly-rectifying channel, subfamily J, member 4 | 0.015 | ||
Cltc | clathrin, heavy polypeptide (Hc) | 0.015 | ||
Hspa1l | heat shock protein 1-like | 0.015 | ||
Gpr162 | G protein-coupled receptor 162 | 0.015 | ||
Ndrg1 | N-myc downstream regulated gene 1 | 0.015 | ||
Ctsl | cathepsin L | 0.015 | ||
Kcnj11 | potassium inwardly rectifying channel, subfamily J, member 11 | 0.015 | ||
Mprip | myosin phosphatase Rho interacting protein | 0.015 | ||
Ercc2 | excision repair cross-complementing rodent repair deficiency, complementation group 2 | 0.015 | ||
Gpr27 | G protein-coupled receptor 27 | 0.015 | ||
Rgs7bp | regulator of G-protein signalling 7 binding protein | 0.015 | ||
Lrfn2 | leucine rich repeat and fibronectin type III domain containing 2 | 0.015 | ||
Lphn1 | latrophilin 1 | 0.015 | ||
Sec61g | SEC61, gamma subunit | 0.015 | ||
Ap2b1 | adaptor-related protein complex 2, beta 1 subunit | 0.014 | ||
Nol6 | nucleolar protein family 6 (RNA-associated) | 0.014 | ||
Cntfr | ciliary neurotrophic factor receptor | 0.014 | ||
Pcp2 | Purkinje cell protein 2 (L7) | 0.014 | ||
Nlgn3 | neuroligin 3 | 0.014 | ||
Chrna4 | cholinergic receptor, nicotinic, alpha polypeptide 4 | 0.014 | ||
Dnajb5 | DnaJ (Hsp40) homolog, subfamily B, member 5 | 0.014 | ||
Cacnb2 | calcium channel, voltage-dependent, beta 2 subunit | 0.014 | ||
Bcap31 | B-cell receptor-associated protein 31 | 0.014 | ||
Cdk14 | cyclin-dependent kinase 14 | 0.014 | ||
Eml6 | echinoderm microtubule associated protein like 6 | 0.014 | ||
Tspan7 | tetraspanin 7 | 0.014 | ||
Actl7b | actin-like 7b | 0.014 | ||
AI118078 | expressed sequence AI118078 | 0.014 | ||
Palm2 | paralemmin 2 | 0.014 | ||
Foxk1 | forkhead box K1 | 0.014 | ||
Ids | iduronate 2-sulfatase | 0.014 | ||
Dchs1 | dachsous 1 (Drosophila) | 0.014 | ||
Gabra2 | gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2 | 0.014 | ||
Adam1a | a disintegrin and metallopeptidase domain 1a | 0.014 | ||
Limch1 | LIM and calponin homology domains 1 | 0.013 | ||
Fv1 | Friend virus susceptibility 1 | 0.013 | ||
Shank2 | SH3/ankyrin domain gene 2 | 0.013 | ||
Lgi1 | leucine-rich repeat LGI family, member 1 | 0.013 | ||
Degs1 | degenerative spermatocyte homolog 1 (Drosophila) | 0.013 | ||
Neurod1 | neurogenic differentiation 1 | 0.013 | ||
Cckbr | cholecystokinin B receptor | 0.013 | ||
Ckm | creatine kinase, muscle | 0.013 | ||
Avpi1 | arginine vasopressin-induced 1 | 0.013 | ||
Shc2 | SHC (Src homology 2 domain containing) transforming protein 2 | 0.013 | ||
Arc | activity regulated cytoskeletal-associated protein | 0.013 | ||
Dvl1 | dishevelled, dsh homolog 1 (Drosophila) | 0.013 | ||
Tom1l2 | target of myb1-like 2 (chicken) | 0.013 | ||
Nbea | neurobeachin | 0.013 | ||
Kcnab3 | potassium voltage-gated channel, shaker-related subfamily, beta member 3 | 0.013 | ||
Bhlhe40 | basic helix-loop-helix family, member e40 | 0.013 | ||
Arhgef17 | Rho guanine nucleotide exchange factor (GEF) 17 | 0.013 | ||
Gys1 | glycogen synthase 1, muscle | 0.013 | ||
Fam115a | family with sequence similarity 115, member A | 0.013 | ||
Arhgap32 | Rho GTPase activating protein 32 | 0.013 | ||
Fancc | Fanconi anemia, complementation group C | 0.013 | ||
Nos1 | nitric oxide synthase 1, neuronal | 0.013 | ||
Sstr2 | somatostatin receptor 2 | 0.013 | ||
C80012 | expressed sequence C80012 | 0.013 | ||
Fat4 | FAT tumor suppressor homolog 4 (Drosophila) | 0.013 | ||
Limk1 | LIM-domain containing, protein kinase | 0.013 | ||
Slc34a1 | solute carrier family 34 (sodium phosphate), member 1 | 0.013 | ||
Pde3a | phosphodiesterase 3A, cGMP inhibited | 0.013 | ||
Ctsd | cathepsin D | 0.012 | ||
Phex | phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets) | 0.012 | ||
Kcnd3 | potassium voltage-gated channel, Shal-related family, member 3 | 0.012 | ||
Plcb1 | phospholipase C, beta 1 | 0.012 | Human | |
Mt2 | metallothionein 2 | 0.012 | ||
Rgs6 | regulator of G-protein signaling 6 | 0.012 | ||
Plin2 | perilipin 2 | 0.012 | ||
Stxbp5l | syntaxin binding protein 5-like | 0.012 | ||
Inca1 | inhibitor of CDK, cyclin A1 interacting protein 1 | 0.012 | ||
Rab36 | RAB36, member RAS oncogene family | 0.012 | ||
Cnnm1 | cyclin M1 | 0.012 | ||
Dpysl2 | dihydropyrimidinase-like 2 | 0.012 | ||
Camk2b | calcium/calmodulin-dependent protein kinase II, beta | 0.012 | ||
Ifitm3 | interferon induced transmembrane protein 3 | 0.012 | ||
Clip2 | CAP-GLY domain containing linker protein 2 | 0.012 | ||
Kif1a | kinesin family member 1A | 0.012 | ||
Rgs9 | regulator of G-protein signaling 9 | 0.012 | ||
Ncald | neurocalcin delta | 0.012 | ||
Olfr16 | olfactory receptor 16 | 0.012 | ||
Nsf | N-ethylmaleimide sensitive fusion protein | 0.012 | ||
Anxa5 | annexin A5 | 0.012 | ||
Dnm3 | dynamin 3 | 0.012 | ||
Fam20c | family with sequence similarity 20, member C | 0.012 | ||
Crat | carnitine acetyltransferase | 0.012 | ||
Chmp2a | chromatin modifying protein 2A | 0.012 | ||
Eda | ectodysplasin-A | 0.012 | ||
Anxa4 | annexin A4 | 0.012 | ||
Nfib | nuclear factor I/B | 0.011 | ||
Efna5 | ephrin A5 | 0.011 | ||
Bhlhe41 | basic helix-loop-helix family, member e41 | 0.011 | ||
Pde7b | phosphodiesterase 7B | 0.011 | ||
Prdm8 | PR domain containing 8 | 0.011 | ||
Atp1a2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | 0.011 | ||
Map2k7 | mitogen-activated protein kinase kinase 7 | 0.011 | ||
Akap5 | A kinase (PRKA) anchor protein 5 | 0.011 | ||
Zfp358 | zinc finger protein 358 | 0.011 | ||
Anks1b | ankyrin repeat and sterile alpha motif domain containing 1B | 0.011 | ||
Sobp | sine oculis-binding protein homolog (Drosophila) | 0.011 | ||
Mamld1 | mastermind-like domain containing 1 | 0.011 | ||
Lamp1 | lysosomal-associated membrane protein 1 | 0.011 | ||
Ntrk3 | neurotrophic tyrosine kinase, receptor, type 3 | 0.011 | ||
Fam78b | family with sequence similarity 78, member B | 0.011 | ||
Adarb1 | adenosine deaminase, RNA-specific, B1 | 0.011 | ||
Akr1a4 | aldo-keto reductase family 1, member A4 (aldehyde reductase) | 0.011 | ||
Slc27a4 | solute carrier family 27 (fatty acid transporter), member 4 | 0.011 | ||
Camk4 | calcium/calmodulin-dependent protein kinase IV | 0.011 | ||
Tpp1 | tripeptidyl peptidase I | 0.011 | ||
Gabra3 | gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3 | 0.011 | ||
Grik2 | glutamate receptor, ionotropic, kainate 2 (beta 2) | 0.011 | ||
Ppp6r2 | protein phosphatase 6, regulatory subunit 2 | 0.011 | ||
Exoc4 | exocyst complex component 4 | 0.011 | ||
Lingo2 | leucine rich repeat and Ig domain containing 2 | 0.011 | ||
Gucy1a3 | guanylate cyclase 1, soluble, alpha 3 | 0.011 | ||
Plxna2 | plexin A2 | 0.011 | ||
Kcnab1 | potassium voltage-gated channel, shaker-related subfamily, beta member 1 | 0.011 | ||
Pcx | pyruvate carboxylase | 0.011 | ||
Chrm4 | cholinergic receptor, muscarinic 4 | 0.011 | ||
Pax6 | paired box gene 6 | 0.011 | ||
Add1 | adducin 1 (alpha) | 0.011 | ||
Kcns2 | K+ voltage-gated channel, subfamily S, 2 | 0.011 | ||
Nr6a1 | nuclear receptor subfamily 6, group A, member 1 | 0.011 | ||
Grik5 | glutamate receptor, ionotropic, kainate 5 (gamma 2) | 0.011 | ||
Mt1 | metallothionein 1 | 0.011 | ||
St6galnac6 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 | 0.011 | ||
Slc30a3 | solute carrier family 30 (zinc transporter), member 3 | 0.011 | ||
Slitrk3 | SLIT and NTRK-like family, member 3 | 0.010 | ||
Atg13 | ATG13 autophagy related 13 homolog (S. cerevisiae) | 0.010 | ||
Acot9 | acyl-CoA thioesterase 9 | 0.010 | ||
Pcdhb20 | protocadherin beta 20 | 0.010 | ||
Scrn1 | secernin 1 | 0.010 | ||
Nckap1 | NCK-associated protein 1 | 0.010 | ||
Utf1 | undifferentiated embryonic cell transcription factor 1 | 0.010 | ||
Flt1 | FMS-like tyrosine kinase 1 | 0.010 | ||
Olfr70 | olfactory receptor 70 | 0.010 | ||
Cit | citron | 0.010 | ||
Sox5 | SRY-box containing gene 5 | 0.010 | ||
Negr1 | neuronal growth regulator 1 | 0.010 | ||
Lgals1 | lectin, galactose binding, soluble 1 | 0.010 | ||
Ahdc1 | AT hook, DNA binding motif, containing 1 | 0.010 | ||
Amh | anti-Mullerian hormone | 0.010 | ||
Lgmn | legumain | 0.010 | ||
Gnaq | guanine nucleotide binding protein, alpha q polypeptide | 0.010 | ||
Dgkb | diacylglycerol kinase, beta | 0.010 | ||
Gucy1b3 | guanylate cyclase 1, soluble, beta 3 | 0.010 | ||
C78444 | expressed sequence C78444 | 0.010 | ||
Phactr1 | phosphatase and actin regulator 1 | 0.010 | ||
Cd9 | CD9 antigen | 0.010 | ||
Lrrc8a | leucine rich repeat containing 8A | 0.010 | ||
Slc12a5 | solute carrier family 12, member 5 | 0.010 | ||
4833424O15Rik | RIKEN cDNA 4833424O15 gene | 0.010 |