IMP: Integrative Multi-species Prediction

Mus musculus

0 genes annotated in mouse

kidney cancer

DOID:263

A urinary system cancer that is located in the kidney.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "kidney cancer" (in gray)

Name	Description	Probability	Func Analog Organism
Gab1	growth factor receptor bound protein 2-associated protein 1	0.965
Brca1	breast cancer 1	0.626
Vegfa	vascular endothelial growth factor A	0.602
Bcl2	B-cell leukemia/lymphoma 2	0.545
Epas1	endothelial PAS domain protein 1	0.386
Prkci	protein kinase C, iota	0.385
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.351
Rxra	retinoid X receptor alpha	0.335
Cd151	CD151 antigen	0.308
Kit	kit oncogene	0.280
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.193
Smad3	MAD homolog 3 (Drosophila)	0.187
Hif1a	hypoxia inducible factor 1, alpha subunit	0.148
Itga3	integrin alpha 3	0.121
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.119
Ilk	integrin linked kinase	0.105
Gdnf	glial cell line derived neurotrophic factor	0.100
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.100
Gpr172b	G protein-coupled receptor 172B	0.099
Kif3b	kinesin family member 3B	0.094
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.093
Col4a3	collagen, type IV, alpha 3	0.087
Hnf1b	HNF1 homeobox B	0.083	Human
Fadd	Fas (TNFRSF6)-associated via death domain	0.082
Egfl8	EGF-like domain 8	0.080
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.079
Thbs1	thrombospondin 1	0.074
Trp53	transformation related protein 53	0.067
Pax2	paired box gene 2	0.067
Epor	erythropoietin receptor	0.066
Notch2	Notch gene homolog 2 (Drosophila)	0.065
Lama5	laminin, alpha 5	0.065
Egln1	EGL nine homolog 1 (C. elegans)	0.059
Vhl	von Hippel-Lindau tumor suppressor	0.056	Human
Tert	telomerase reverse transcriptase	0.050
Mpv17	MpV17 mitochondrial inner membrane protein	0.047
Rab25	RAB25, member RAS oncogene family	0.047
Ptgs2	prostaglandin-endoperoxide synthase 2	0.047
Lepr	leptin receptor	0.045
Bicc1	bicaudal C homolog 1 (Drosophila)	0.042
Emx2	empty spiracles homolog 2 (Drosophila)	0.042
Usp42	ubiquitin specific peptidase 42	0.041
Nphs2	nephrosis 2 homolog, podocin (human)	0.040
Lhx1	LIM homeobox protein 1	0.039
Nos3	nitric oxide synthase 3, endothelial cell	0.038
Tmprss2	transmembrane protease, serine 2	0.036
Llgl2	lethal giant larvae homolog 2 (Drosophila)	0.036
Mas1	MAS1 oncogene	0.035
Stk11	serine/threonine kinase 11	0.034
Foxo4	forkhead box O4	0.031
Phf7	PHD finger protein 7	0.028
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.027
Ren1	renin 1 structural	0.027
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.027
Apc	adenomatosis polyposis coli	0.025
Hes1	hairy and enhancer of split 1 (Drosophila)	0.024
Apoe	apolipoprotein E	0.023
Esrp2	epithelial splicing regulatory protein 2	0.023
Slc44a4	solute carrier family 44, member 4	0.023
Pparg	peroxisome proliferator activated receptor gamma	0.022
Ascl2	achaete-scute complex homolog 2 (Drosophila)	0.022
Fgfr2	fibroblast growth factor receptor 2	0.022
Cog1	component of oligomeric golgi complex 1	0.021
Wt1	Wilms tumor 1 homolog	0.021	Human
Prkcz	protein kinase C, zeta	0.021
Atm	ataxia telangiectasia mutated homolog (human)	0.019
Wrn	Werner syndrome homolog (human)	0.019
Tcf21	transcription factor 21	0.019
Cdh1	cadherin 1	0.018
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.018
Cldn3	claudin 3	0.018
Rbx1	ring-box 1	0.018
Fam83g	family with sequence similarity 83, member G	0.018
Ppard	peroxisome proliferator activator receptor delta	0.017
Pcbd1	pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1	0.016
1110014N23Rik	RIKEN cDNA 1110014N23 gene	0.016
Zbtb37	zinc finger and BTB domain containing 37	0.016
Fas	Fas (TNF receptor superfamily member 6)	0.016
Dpysl2	dihydropyrimidinase-like 2	0.016
Slc5a2	solute carrier family 5 (sodium/glucose cotransporter), member 2	0.015
Hpn	hepsin	0.015
Mapk14	mitogen-activated protein kinase 14	0.015
Hist2h2ab	histone cluster 2, H2ab	0.015
Mdm2	transformed mouse 3T3 cell double minute 2	0.015
Muc1	mucin 1, transmembrane	0.014
Fstl3	follistatin-like 3	0.014
Dapk3	death-associated protein kinase 3	0.014
Top3a	topoisomerase (DNA) III alpha	0.014
Ar	androgen receptor	0.014
Rara	retinoic acid receptor, alpha	0.013
Tiam2	T-cell lymphoma invasion and metastasis 2	0.013
Stc2	stanniocalcin 2	0.013
Grb7	growth factor receptor bound protein 7	0.013
Fzd7	frizzled homolog 7 (Drosophila)	0.013
Ocln	occludin	0.013
Wwc1	WW, C2 and coiled-coil domain containing 1	0.012
Pten	phosphatase and tensin homolog	0.012
Phlda2	pleckstrin homology-like domain, family A, member 2	0.012
Pknox1	Pbx/knotted 1 homeobox	0.012
Spint1	serine protease inhibitor, Kunitz type 1	0.012
Kif3a	kinesin family member 3A	0.012
Ihh	Indian hedgehog	0.011
Dok1	docking protein 1	0.011
Usp12	ubiquitin specific peptidase 12	0.011
Hbb-b1	hemoglobin, beta adult major chain	0.011
Fut7	fucosyltransferase 7	0.011
Usp22	ubiquitin specific peptidase 22	0.011
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.011
Mipol1	mirror-image polydactyly gene 1 homolog (human)	0.011
Fut4	fucosyltransferase 4	0.011
Myo1e	myosin IE	0.011
Cpsf3l	cleavage and polyadenylation specific factor 3-like	0.010
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.010