IMP: Integrative Multi-species Prediction

Mus musculus

0 genes annotated in mouse

glucose metabolism disease

DOID:4194

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Gene Predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "glucose metabolism disease" (in gray)

Name	Description	Probability	Func Analog Organism
Lepr	leptin receptor	1.000
Lep	leptin	0.944
Insr	insulin receptor	0.758
Plin1	perilipin 1	0.669
Ghr	growth hormone receptor	0.620
Cav1	caveolin 1, caveolae protein	0.616
Onecut1	one cut domain, family member 1	0.451
Thra	thyroid hormone receptor alpha	0.414
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.404
Ldha	lactate dehydrogenase A	0.382
Ins2	insulin II	0.360
Irs2	insulin receptor substrate 2	0.349	Human
Nos1	nitric oxide synthase 1, neuronal	0.307
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.294
Sim1	single-minded homolog 1 (Drosophila)	0.275
Stat3	signal transducer and activator of transcription 3	0.230
Akt1	thymoma viral proto-oncogene 1	0.206
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.192
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.172
Ptf1a	pancreas specific transcription factor, 1a	0.159
Cdx2	caudal type homeobox 2	0.157
Irs1	insulin receptor substrate 1	0.156	Human
Fas	Fas (TNF receptor superfamily member 6)	0.148
Kiss1	KiSS-1 metastasis-suppressor	0.141
Pnpla2	patatin-like phospholipase domain containing 2	0.141
Pdx1	pancreatic and duodenal homeobox 1	0.141	Human
Prf1	perforin 1 (pore forming protein)	0.131
Il6st	interleukin 6 signal transducer	0.129
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.129
Tab1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.119
Tlr4	toll-like receptor 4	0.119
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.118
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.116
Mstn	myostatin	0.115
Foxa2	forkhead box A2	0.113
Il1r1	interleukin 1 receptor, type I	0.109
Insm1	insulinoma-associated 1	0.103
Ar	androgen receptor	0.102
Hes1	hairy and enhancer of split 1 (Drosophila)	0.096
Ifng	interferon gamma	0.093
Sycn	syncollin	0.084
Socs3	suppressor of cytokine signaling 3	0.084
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.083
Mark2	MAP/microtubule affinity-regulating kinase 2	0.081
Kl	klotho	0.077
Tnf	tumor necrosis factor	0.077
Rag1	recombination activating gene 1	0.077
Apoe	apolipoprotein E	0.076
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.072
Cd19	CD19 antigen	0.069
Hr	hairless	0.068
Nos2	nitric oxide synthase 2, inducible	0.068
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.066
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.065
Taf3	TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor	0.064
Lrp1	low density lipoprotein receptor-related protein 1	0.063
Neurog2	neurogenin 2	0.063
Npc1	Niemann Pick type C1	0.063
Cd28	CD28 antigen	0.059
Zfp592	zinc finger protein 592	0.058
Lhx3	LIM homeobox protein 3	0.055
Drd2	dopamine receptor D2	0.054
Agpat2	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)	0.052
Cyp2d26	cytochrome P450, family 2, subfamily d, polypeptide 26	0.052
Mpv17	MpV17 mitochondrial inner membrane protein	0.052
Nos3	nitric oxide synthase 3, endothelial cell	0.052
Pparg	peroxisome proliferator activated receptor gamma	0.052	Human
Neurod4	neurogenic differentiation 4	0.051
Ldlr	low density lipoprotein receptor	0.050
Nkx6-1	NK6 homeobox 1	0.050
Gcgr	glucagon receptor	0.049
Aldoa	aldolase A, fructose-bisphosphate	0.047
Tle3	transducin-like enhancer of split 3, homolog of Drosophila E(spl)	0.047
Lpin1	lipin 1	0.047
Bscl2	Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)	0.046
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.045
Esr1	estrogen receptor 1 (alpha)	0.045
Sykb	spleen tyrosine kinase	0.044
Galnt3	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3	0.044
Spp1	secreted phosphoprotein 1	0.044
Ikzf1	IKAROS family zinc finger 1	0.044
Gckr	glucokinase regulatory protein	0.043
Emx1	empty spiracles homolog 1 (Drosophila)	0.043
Tnip1	TNFAIP3 interacting protein 1	0.042
Lyz2	lysozyme 2	0.040
Atoh7	atonal homolog 7 (Drosophila)	0.040
Lmna	lamin A	0.040
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.039
Apoa1	apolipoprotein A-I	0.039
Bicc1	bicaudal C homolog 1 (Drosophila)	0.039
Eif2c2	eukaryotic translation initiation factor 2C, 2	0.039
Cd44	CD44 antigen	0.039
Igh	immunoglobulin heavy chain complex	0.039
Stat5a	signal transducer and activator of transcription 5A	0.038
Il4	interleukin 4	0.038
Il10	interleukin 10	0.037
Ccl2	chemokine (C-C motif) ligand 2	0.037
Il2	interleukin 2	0.037
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.036
Foxa3	forkhead box A3	0.036
Npy2r	neuropeptide Y receptor Y2	0.035
Atp7b	ATPase, Cu++ transporting, beta polypeptide	0.035
Neo1	neogenin	0.035
Crb3	crumbs homolog 3 (Drosophila)	0.034
Ptgs2	prostaglandin-endoperoxide synthase 2	0.033
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.033
Hnf4a	hepatic nuclear factor 4, alpha	0.033	Human
Rag2	recombination activating gene 2	0.033
Prkcd	protein kinase C, delta	0.032
Lhx5	LIM homeobox protein 5	0.032
Lrp4	low density lipoprotein receptor-related protein 4	0.031
Card11	caspase recruitment domain family, member 11	0.031
App	amyloid beta (A4) precursor protein	0.030
Irf7	interferon regulatory factor 7	0.030
Neurog3	neurogenin 3	0.029
Met	met proto-oncogene	0.029
Col1a1	collagen, type I, alpha 1	0.029
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.028
Pklr	pyruvate kinase liver and red blood cell	0.028
Tcra	T-cell receptor alpha chain	0.028
Nr1h4	nuclear receptor subfamily 1, group H, member 4	0.028
Ptprc	protein tyrosine phosphatase, receptor type, C	0.028
Prkci	protein kinase C, iota	0.027
Mbl2	mannose-binding lectin (protein C) 2	0.027
Ank	progressive ankylosis	0.027
Prox1	prospero-related homeobox 1	0.027
Traf3ip2	TRAF3 interacting protein 2	0.026
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.026
Nlrp3	NLR family, pyrin domain containing 3	0.026
Cidec	cell death-inducing DFFA-like effector c	0.026
Ahr	aryl-hydrocarbon receptor	0.026
Map3k12	mitogen-activated protein kinase kinase kinase 12	0.026
Abcb4	ATP-binding cassette, sub-family B (MDR/TAP), member 4	0.025
Ccr2	chemokine (C-C motif) receptor 2	0.024
Tlr2	toll-like receptor 2	0.024
Vdr	vitamin D receptor	0.024
Pstpip2	proline-serine-threonine phosphatase-interacting protein 2	0.024
Zg16	zymogen granule protein 16	0.024
Baat	bile acid-Coenzyme A: amino acid N-acyltransferase	0.023
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.023
Foxn1	forkhead box N1	0.023
Csnk1g2	casein kinase 1, gamma 2	0.023
Aplp1	amyloid beta (A4) precursor-like protein 1	0.023
Lipe	lipase, hormone sensitive	0.023
Pkm2	pyruvate kinase, muscle	0.022
Mmp9	matrix metallopeptidase 9	0.022
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.022
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.022
Notch1	Notch gene homolog 1 (Drosophila)	0.022
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.022
Nfil3	nuclear factor, interleukin 3, regulated	0.021
Myd88	myeloid differentiation primary response gene 88	0.021
Pgm2	phosphoglucomutase 2	0.021
Myt1	myelin transcription factor 1	0.021
4933407C03Rik	RIKEN cDNA 4933407C03 gene	0.021
Slc6a8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8	0.021
Hmga2	high mobility group AT-hook 2	0.021
Slc25a48	solute carrier family 25, member 48	0.020
Arx	aristaless related homeobox	0.020
Esr2	estrogen receptor 2 (beta)	0.020
Agrp	agouti related protein	0.020
Cldn2	claudin 2	0.020
Tert	telomerase reverse transcriptase	0.020
Tat	tyrosine aminotransferase	0.020
Ttc7	tetratricopeptide repeat domain 7	0.020
Bach2	BTB and CNC homology 2	0.020
Pten	phosphatase and tensin homolog	0.019
Lat	linker for activation of T cells	0.019
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.019
Dpf3	D4, zinc and double PHD fingers, family 3	0.019
Ncoa1	nuclear receptor coactivator 1	0.019
Hnf4g	hepatocyte nuclear factor 4, gamma	0.019
Adrb3	adrenergic receptor, beta 3	0.019
Runx1	runt related transcription factor 1	0.018
Gjb1	gap junction protein, beta 1	0.018
Pou3f1	POU domain, class 3, transcription factor 1	0.018
Pkhd1	polycystic kidney and hepatic disease 1	0.018
Igf1r	insulin-like growth factor I receptor	0.018
Esrra	estrogen related receptor, alpha	0.018
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.018
Wiz	widely-interspaced zinc finger motifs	0.018
Btbd17	BTB (POZ) domain containing 17	0.017
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.017	Human
Plaur	plasminogen activator, urokinase receptor	0.017
Rab17	RAB17, member RAS oncogene family	0.017
Blnk	B-cell linker	0.017
Hgfac	hepatocyte growth factor activator	0.017
Lrp1b	low density lipoprotein-related protein 1B (deleted in tumors)	0.017
Fgf4	fibroblast growth factor 4	0.017
Kcnh2	potassium voltage-gated channel, subfamily H (eag-related), member 2	0.017
Insrr	insulin receptor-related receptor	0.017
Gdf11	growth differentiation factor 11	0.016
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.016
Soat2	sterol O-acyltransferase 2	0.016
Cdh1	cadherin 1	0.016
Lair1	leukocyte-associated Ig-like receptor 1	0.016
Cpn1	carboxypeptidase N, polypeptide 1	0.016
Scd1	stearoyl-Coenzyme A desaturase 1	0.016
Apob	apolipoprotein B	0.016
Nhlh2	nescient helix loop helix 2	0.016
Mapkapk2	MAP kinase-activated protein kinase 2	0.016
Adrb1	adrenergic receptor, beta 1	0.016
Fzd7	frizzled homolog 7 (Drosophila)	0.016
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.016
Cnga3	cyclic nucleotide gated channel alpha 3	0.016
Prl	prolactin	0.015
Slc12a5	solute carrier family 12, member 5	0.015
Ncoa3	nuclear receptor coactivator 3	0.015
Trp53	transformation related protein 53	0.015
Rundc3a	RUN domain containing 3A	0.015
Pcsk2	proprotein convertase subtilisin/kexin type 2	0.015
Isl1	ISL1 transcription factor, LIM/homeodomain	0.015
Gpd2	glycerol phosphate dehydrogenase 2, mitochondrial	0.015	Human
Stat5b	signal transducer and activator of transcription 5B	0.015
Pgk1	phosphoglycerate kinase 1	0.015
Apoa4	apolipoprotein A-IV	0.015
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.015
Rtp4	receptor transporter protein 4	0.015
Fgf15	fibroblast growth factor 15	0.015
Cdhr5	cadherin-related family member 5	0.014
Mad2l2	MAD2 mitotic arrest deficient-like 2 (yeast)	0.014
Fam20c	family with sequence similarity 20, member C	0.014
Prlr	prolactin receptor	0.014
Ggnbp1	gametogenetin binding protein 1	0.014
Enc1	ectodermal-neural cortex 1	0.014
Syt5	synaptotagmin V	0.014
Kcnn1	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1	0.014
Ddx60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.014
Onecut2	one cut domain, family member 2	0.014
Eif2ak3	eukaryotic translation initiation factor 2 alpha kinase 3	0.014
Habp2	hyaluronic acid binding protein 2	0.014
Fyn	Fyn proto-oncogene	0.014
Aldob	aldolase B, fructose-bisphosphate	0.014
Epha2	Eph receptor A2	0.014
Usp18	ubiquitin specific peptidase 18	0.014
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.014
Oas1d	2'-5' oligoadenylate synthetase 1D	0.014
Hrg	histidine-rich glycoprotein	0.014
Bsg	basigin	0.014
Ccr7	chemokine (C-C motif) receptor 7	0.014
Chaf1a	chromatin assembly factor 1, subunit A (p150)	0.013
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.013
Nr6a1	nuclear receptor subfamily 6, group A, member 1	0.013
Adra1b	adrenergic receptor, alpha 1b	0.013
Olfr90	olfactory receptor 90	0.013
Adipoq	adiponectin, C1Q and collagen domain containing	0.013
Lonp1	lon peptidase 1, mitochondrial	0.013
Aadac	arylacetamide deacetylase (esterase)	0.013
Gpi1	glucose phosphate isomerase 1	0.013
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.013
BC018242	cDNA sequence BC018242	0.013
Zfhx3	zinc finger homeobox 3	0.013
Sik3	SIK family kinase 3	0.013
Prodh2	proline dehydrogenase (oxidase) 2	0.013
Serpina10	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.013
Pbsn	probasin	0.013
Brd2	bromodomain containing 2	0.013
Junb	Jun-B oncogene	0.013
Muc13	mucin 13, epithelial transmembrane	0.013
Cacna1a	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.013
Gsdma3	gasdermin A3	0.013
AI118078	expressed sequence AI118078	0.013
Zfhx4	zinc finger homeodomain 4	0.013
Slc22a6	solute carrier family 22 (organic anion transporter), member 6	0.013
Sqstm1	sequestosome 1	0.013
Ikbkg	inhibitor of kappaB kinase gamma	0.013
Purb	purine rich element binding protein B	0.013
Fzd8	frizzled homolog 8 (Drosophila)	0.013
Hoxc8	homeobox C8	0.013
Gm13290	predicted gene 13290	0.013
Rxra	retinoid X receptor alpha	0.013
Cdkn2d	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	0.012
Epo	erythropoietin	0.012
AI428936	expressed sequence AI428936	0.012
Galr1	galanin receptor 1	0.012
Stk36	serine/threonine kinase 36 (fused homolog, Drosophila)	0.012
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.012
A1cf	APOBEC1 complementation factor	0.012
Fosl2	fos-like antigen 2	0.012
Mgat3	mannoside acetylglucosaminyltransferase 3	0.012
Camk2b	calcium/calmodulin-dependent protein kinase II, beta	0.012
H1f0	H1 histone family, member 0	0.012
Sox11	SRY-box containing gene 11	0.012
Slc22a12	solute carrier family 22 (organic anion/cation transporter), member 12	0.012
Pigr	polymeric immunoglobulin receptor	0.012
Lipa	lysosomal acid lipase A	0.012
Nr1i3	nuclear receptor subfamily 1, group I, member 3	0.012
Wnk4	WNK lysine deficient protein kinase 4	0.012
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.012
Prkce	protein kinase C, epsilon	0.012
Saa4	serum amyloid A 4	0.012
Prkaca	protein kinase, cAMP dependent, catalytic, alpha	0.012
Mogat2	monoacylglycerol O-acyltransferase 2	0.012
Hsd17b1	hydroxysteroid (17-beta) dehydrogenase 1	0.012
Esrp2	epithelial splicing regulatory protein 2	0.012
Nfib	nuclear factor I/B	0.012
Kifc2	kinesin family member C2	0.012
Olfr94	olfactory receptor 94	0.012
Grb10	growth factor receptor bound protein 10	0.012
Isg15	ISG15 ubiquitin-like modifier	0.012
Gab1	growth factor receptor bound protein 2-associated protein 1	0.012
F2	coagulation factor II	0.012
Apba3	amyloid beta (A4) precursor protein-binding, family A, member 3	0.011
Cdx1	caudal type homeobox 1	0.011
Hes5	hairy and enhancer of split 5 (Drosophila)	0.011
Nfia	nuclear factor I/A	0.011
Crb2	crumbs homolog 2 (Drosophila)	0.011
Trfr2	transferrin receptor 2	0.011
Glis3	GLIS family zinc finger 3	0.011
Npas1	neuronal PAS domain protein 1	0.011
Pcsk4	proprotein convertase subtilisin/kexin type 4	0.011
Fbp2	fructose bisphosphatase 2	0.011
Hsd3b5	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5	0.011
Pax6	paired box gene 6	0.011
H2-Ab1	histocompatibility 2, class II antigen A, beta 1	0.011
Epb4.1l4b	erythrocyte protein band 4.1-like 4b	0.011
Sstr3	somatostatin receptor 3	0.011
Vmn1r14	vomeronasal 1 receptor 14	0.011
Odz4	odd Oz/ten-m homolog 4 (Drosophila)	0.011
Clps	colipase, pancreatic	0.011
B4galnt2	beta-1,4-N-acetyl-galactosaminyl transferase 2	0.011
Clock	circadian locomotor output cycles kaput	0.011
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.011
Gadd45g	growth arrest and DNA-damage-inducible 45 gamma	0.011
Tnfaip8l2	tumor necrosis factor, alpha-induced protein 8-like 2	0.011
Fam46a	family with sequence similarity 46, member A	0.011
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.011
Cyp26c1	cytochrome P450, family 26, subfamily c, polypeptide 1	0.011
Inpp5a	inositol polyphosphate-5-phosphatase A	0.011
Arpc2	actin related protein 2/3 complex, subunit 2	0.011
Mapk15	mitogen-activated protein kinase 15	0.011
Kcnb1	potassium voltage gated channel, Shab-related subfamily, member 1	0.011
Adcy9	adenylate cyclase 9	0.011
Bcl2a1d	B-cell leukemia/lymphoma 2 related protein A1d	0.011
D19Wsu162e	DNA segment, Chr 19, Wayne State University 162, expressed	0.011
C4bp	complement component 4 binding protein	0.011
Ern2	endoplasmic reticulum (ER) to nucleus signalling 2	0.011
Igf1	insulin-like growth factor 1	0.011
Arhgef16	Rho guanine nucleotide exchange factor (GEF) 16	0.011
Arhgap8	Rho GTPase activating protein 8	0.011
Ikzf3	IKAROS family zinc finger 3	0.011
Rbm42	RNA binding motif protein 42	0.011
Zfp518b	zinc finger protein 518B	0.011
Drd3	dopamine receptor D3	0.011
Slc5a2	solute carrier family 5 (sodium/glucose cotransporter), member 2	0.011
Clrn3	clarin 3	0.011
Vim	vimentin	0.010
Osbp	oxysterol binding protein	0.010
Gck	glucokinase	0.010	Human
Dsg4	desmoglein 4	0.010
Cpe	carboxypeptidase E	0.010
Celsr2	cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)	0.010
Gh	growth hormone	0.010
Uroc1	urocanase domain containing 1	0.010
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.010
Stim1	stromal interaction molecule 1	0.010
Cdhr2	cadherin-related family member 2	0.010
Kit	kit oncogene	0.010
Fabp6	fatty acid binding protein 6, ileal (gastrotropin)	0.010
Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	0.010
Vav2	vav 2 oncogene	0.010
Wnt8a	wingless-related MMTV integration site 8A	0.010
Apbb1	amyloid beta (A4) precursor protein-binding, family B, member 1	0.010
Acsm2	acyl-CoA synthetase medium-chain family member 2	0.010
Ms4a13	membrane-spanning 4-domains, subfamily A, member 13	0.010
Elavl4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)	0.010
Slc25a44	solute carrier family 25, member 44	0.010
Itih1	inter-alpha trypsin inhibitor, heavy chain 1	0.010
Thbs1	thrombospondin 1	0.010
Jund	Jun proto-oncogene related gene d	0.010
Jak2	Janus kinase 2	0.010
Pstpip1	proline-serine-threonine phosphatase-interacting protein 1	0.010
Proc	protein C	0.010
Ctrl	chymotrypsin-like	0.010
Pcbd1	pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1	0.010