IMP
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Mus musculus
0 genes annotated in mouse
colon carcinoma
DOID:1520
A colon cancer that has material basis in abnormally proliferating cells derives from epithelial cells.
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In addition to gene-name show these genes:
Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.866 | Human | |
| Pten | phosphatase and tensin homolog | 0.759 | ||
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.482 | ||
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.471 | ||
| Apc | adenomatosis polyposis coli | 0.453 | Human | |
| Trp53 | transformation related protein 53 | 0.380 | Human | |
| Smad3 | MAD homolog 3 (Drosophila) | 0.156 | ||
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.156 | ||
| Cd44 | CD44 antigen | 0.136 | ||
| Stat3 | signal transducer and activator of transcription 3 | 0.126 | ||
| Smad4 | MAD homolog 4 (Drosophila) | 0.124 | ||
| Bak1 | BCL2-antagonist/killer 1 | 0.117 | ||
| Gsk3b | glycogen synthase kinase 3 beta | 0.117 | ||
| Pik3r1 | phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) | 0.116 | ||
| Kit | kit oncogene | 0.114 | ||
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.111 | ||
| Bcl2 | B-cell leukemia/lymphoma 2 | 0.108 | ||
| Il10 | interleukin 10 | 0.096 | ||
| Vhl | von Hippel-Lindau tumor suppressor | 0.095 | ||
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.079 | ||
| Braf | Braf transforming gene | 0.072 | ||
| Cdk4 | cyclin-dependent kinase 4 | 0.061 | ||
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.058 | ||
| Nf2 | neurofibromatosis 2 | 0.057 | ||
| Sox9 | SRY-box containing gene 9 | 0.057 | ||
| Il6st | interleukin 6 signal transducer | 0.054 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.053 | ||
| Ccnd1 | cyclin D1 | 0.043 | Human | |
| Il1r1 | interleukin 1 receptor, type I | 0.043 | ||
| Cdk6 | cyclin-dependent kinase 6 | 0.042 | ||
| Tgfb1 | transforming growth factor, beta 1 | 0.041 | ||
| Ptch1 | patched homolog 1 | 0.040 | ||
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.039 | ||
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.039 | ||
| Rap2c | RAP2C, member of RAS oncogene family | 0.037 | ||
| Adam17 | a disintegrin and metallopeptidase domain 17 | 0.036 | ||
| Arhgdia | Rho GDP dissociation inhibitor (GDI) alpha | 0.036 | ||
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.035 | ||
| Rb1 | retinoblastoma 1 | 0.034 | ||
| Myd88 | myeloid differentiation primary response gene 88 | 0.033 | ||
| Mybl2 | myeloblastosis oncogene-like 2 | 0.032 | ||
| Gnaq | guanine nucleotide binding protein, alpha q polypeptide | 0.032 | ||
| Lyst | lysosomal trafficking regulator | 0.032 | ||
| Skil | SKI-like | 0.031 | ||
| Mmp9 | matrix metallopeptidase 9 | 0.031 | ||
| Mdm4 | transformed mouse 3T3 cell double minute 4 | 0.031 | ||
| Arpc4 | actin related protein 2/3 complex, subunit 4 | 0.031 | ||
| Akt2 | thymoma viral proto-oncogene 2 | 0.031 | ||
| Shh | sonic hedgehog | 0.031 | ||
| Spred1 | sprouty protein with EVH-1 domain 1, related sequence | 0.029 | ||
| Ncoa3 | nuclear receptor coactivator 3 | 0.029 | ||
| Brca1 | breast cancer 1 | 0.028 | ||
| Myc | myelocytomatosis oncogene | 0.028 | ||
| Trp63 | transformation related protein 63 | 0.027 | ||
| Kitl | kit ligand | 0.026 | ||
| Smad2 | MAD homolog 2 (Drosophila) | 0.026 | ||
| Lef1 | lymphoid enhancer binding factor 1 | 0.026 | ||
| Ep300 | E1A binding protein p300 | 0.025 | Human | |
| Nf1 | neurofibromatosis 1 | 0.025 | ||
| Wdr1 | WD repeat domain 1 | 0.025 | ||
| Pik3cb | phosphatidylinositol 3-kinase, catalytic, beta polypeptide | 0.024 | ||
| Lyz2 | lysozyme 2 | 0.024 | ||
| Gipc1 | GIPC PDZ domain containing family, member 1 | 0.024 | ||
| Bhlhe22 | basic helix-loop-helix family, member e22 | 0.024 | ||
| Tgfbr1 | transforming growth factor, beta receptor I | 0.024 | ||
| Gabrb2 | gamma-aminobutyric acid (GABA) A receptor, subunit beta 2 | 0.023 | ||
| Spp1 | secreted phosphoprotein 1 | 0.023 | ||
| Atp7a | ATPase, Cu++ transporting, alpha polypeptide | 0.023 | ||
| Wdr26 | WD repeat domain 26 | 0.022 | ||
| Cdc20 | cell division cycle 20 homolog (S. cerevisiae) | 0.022 | ||
| Gnai2 | guanine nucleotide binding protein (G protein), alpha inhibiting 2 | 0.022 | ||
| Gnb2 | guanine nucleotide binding protein (G protein), beta 2 | 0.022 | ||
| Dicer1 | Dicer1, Dcr-1 homolog (Drosophila) | 0.021 | ||
| Prkar1a | protein kinase, cAMP dependent regulatory, type I, alpha | 0.021 | ||
| Kcns2 | K+ voltage-gated channel, subfamily S, 2 | 0.021 | ||
| Elavl1 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) | 0.020 | ||
| Fgf9 | fibroblast growth factor 9 | 0.020 | ||
| Rps6ka3 | ribosomal protein S6 kinase polypeptide 3 | 0.019 | ||
| Ckap2 | cytoskeleton associated protein 2 | 0.019 | ||
| Thrb | thyroid hormone receptor beta | 0.019 | ||
| Rac1 | RAS-related C3 botulinum substrate 1 | 0.019 | ||
| Cenpe | centromere protein E | 0.019 | ||
| Huwe1 | HECT, UBA and WWE domain containing 1 | 0.018 | ||
| Ret | ret proto-oncogene | 0.018 | ||
| Vegfa | vascular endothelial growth factor A | 0.018 | ||
| Tsc1 | tuberous sclerosis 1 | 0.018 | ||
| Bmpr2 | bone morphogenic protein receptor, type II (serine/threonine kinase) | 0.018 | ||
| Ccnd3 | cyclin D3 | 0.018 | ||
| Agap3 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 | 0.018 | ||
| Vasp | vasodilator-stimulated phosphoprotein | 0.017 | ||
| Fas | Fas (TNF receptor superfamily member 6) | 0.017 | ||
| Gabrg2 | gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 | 0.017 | ||
| Ctnna1 | catenin (cadherin associated protein), alpha 1 | 0.017 | ||
| Nfe2l2 | nuclear factor, erythroid derived 2, like 2 | 0.017 | ||
| Trim33 | tripartite motif-containing 33 | 0.017 | ||
| Trim46 | tripartite motif-containing 46 | 0.017 | ||
| Actr3 | ARP3 actin-related protein 3 homolog (yeast) | 0.016 | ||
| Tert | telomerase reverse transcriptase | 0.016 | ||
| Ppp4r1 | protein phosphatase 4, regulatory subunit 1 | 0.016 | ||
| Smarcd1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 | 0.016 | ||
| Tlr2 | toll-like receptor 2 | 0.016 | ||
| Tsc2 | tuberous sclerosis 2 | 0.015 | ||
| Pthlh | parathyroid hormone-like peptide | 0.015 | ||
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.015 | ||
| Ticam1 | toll-like receptor adaptor molecule 1 | 0.015 | ||
| Papd5 | PAP associated domain containing 5 | 0.015 | ||
| Shc1 | src homology 2 domain-containing transforming protein C1 | 0.015 | ||
| Ppp4c | protein phosphatase 4, catalytic subunit | 0.015 | ||
| Slc39a7 | solute carrier family 39 (zinc transporter), member 7 | 0.014 | ||
| Atp2b1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.014 | ||
| Shf | Src homology 2 domain containing F | 0.014 | ||
| Agfg1 | ArfGAP with FG repeats 1 | 0.014 | ||
| Ehmt2 | euchromatic histone lysine N-methyltransferase 2 | 0.014 | ||
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.014 | ||
| Kcna6 | potassium voltage-gated channel, shaker-related, subfamily, member 6 | 0.014 | ||
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.014 | ||
| Rnf111 | ring finger 111 | 0.014 | ||
| Coro1c | coronin, actin binding protein 1C | 0.014 | ||
| Cfl1 | cofilin 1, non-muscle | 0.014 | ||
| Ntn1 | netrin 1 | 0.014 | ||
| Gli2 | GLI-Kruppel family member GLI2 | 0.014 | ||
| Lats1 | large tumor suppressor | 0.014 | ||
| Stub1 | STIP1 homology and U-Box containing protein 1 | 0.014 | ||
| Brca2 | breast cancer 2 | 0.014 | ||
| Pparg | peroxisome proliferator activated receptor gamma | 0.013 | ||
| H2afx | H2A histone family, member X | 0.013 | ||
| Ralb | v-ral simian leukemia viral oncogene homolog B (ras related) | 0.013 | ||
| Foxp3 | forkhead box P3 | 0.013 | ||
| Pik3r3 | phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55) | 0.013 | ||
| Irs1 | insulin receptor substrate 1 | 0.013 | ||
| Cdk5r1 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 0.013 | ||
| Esr1 | estrogen receptor 1 (alpha) | 0.013 | ||
| Dusp6 | dual specificity phosphatase 6 | 0.013 | ||
| Cux2 | cut-like homeobox 2 | 0.012 | ||
| Cd14 | CD14 antigen | 0.012 | ||
| Ilk | integrin linked kinase | 0.012 | ||
| Runx1 | runt related transcription factor 1 | 0.012 | ||
| Egr1 | early growth response 1 | 0.012 | ||
| Grm8 | glutamate receptor, metabotropic 8 | 0.012 | ||
| Obfc2b | oligonucleotide/oligosaccharide-binding fold containing 2B | 0.012 | ||
| Ly96 | lymphocyte antigen 96 | 0.012 | ||
| Itga6 | integrin alpha 6 | 0.012 | ||
| Il6 | interleukin 6 | 0.012 | ||
| Cbl | Casitas B-lineage lymphoma | 0.012 | ||
| Ptpn12 | protein tyrosine phosphatase, non-receptor type 12 | 0.012 | Human | |
| Hipk1 | homeodomain interacting protein kinase 1 | 0.012 | ||
| Cdc42se1 | CDC42 small effector 1 | 0.012 | ||
| Apaf1 | apoptotic peptidase activating factor 1 | 0.012 | ||
| Tpm4 | tropomyosin 4 | 0.012 | ||
| Morf4l2 | mortality factor 4 like 2 | 0.012 | ||
| Hprt | hypoxanthine guanine phosphoribosyl transferase | 0.012 | ||
| Rasa2 | RAS p21 protein activator 2 | 0.012 | ||
| Casp1 | caspase 1 | 0.012 | ||
| Pak2 | p21 protein (Cdc42/Rac)-activated kinase 2 | 0.012 | ||
| Adcy8 | adenylate cyclase 8 | 0.012 | ||
| Gli3 | GLI-Kruppel family member GLI3 | 0.012 | ||
| Epc2 | enhancer of polycomb homolog 2 (Drosophila) | 0.011 | ||
| Csf1 | colony stimulating factor 1 (macrophage) | 0.011 | ||
| Bmp7 | bone morphogenetic protein 7 | 0.011 | ||
| Bcl10 | B-cell leukemia/lymphoma 10 | 0.011 | ||
| F9 | coagulation factor IX | 0.011 | ||
| Fbxo15 | F-box protein 15 | 0.011 | ||
| E2f1 | E2F transcription factor 1 | 0.011 | ||
| Clip2 | CAP-GLY domain containing linker protein 2 | 0.011 | ||
| Arhgap1 | Rho GTPase activating protein 1 | 0.011 | ||
| Bcl2l1 | BCL2-like 1 | 0.011 | ||
| Ceacam2 | carcinoembryonic antigen-related cell adhesion molecule 2 | 0.011 | ||
| Mgat3 | mannoside acetylglucosaminyltransferase 3 | 0.011 | ||
| Lepr | leptin receptor | 0.011 | ||
| Ifrd1 | interferon-related developmental regulator 1 | 0.011 | ||
| Stat6 | signal transducer and activator of transcription 6 | 0.011 | ||
| Slc7a1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.011 | ||
| Lcor | ligand dependent nuclear receptor corepressor | 0.011 | ||
| Gja1 | gap junction protein, alpha 1 | 0.011 | ||
| Thbs1 | thrombospondin 1 | 0.011 | ||
| Pou3f3 | POU domain, class 3, transcription factor 3 | 0.011 | ||
| Srsf9 | serine/arginine-rich splicing factor 9 | 0.011 | ||
| Mecp2 | methyl CpG binding protein 2 | 0.011 | ||
| Nt5c | 5',3'-nucleotidase, cytosolic | 0.011 | ||
| Arpc3 | actin related protein 2/3 complex, subunit 3 | 0.011 | ||
| Sos2 | son of sevenless homolog 2 (Drosophila) | 0.011 | ||
| Tmed10 | transmembrane emp24-like trafficking protein 10 (yeast) | 0.011 | ||
| Rara | retinoic acid receptor, alpha | 0.011 | ||
| Arf3 | ADP-ribosylation factor 3 | 0.010 | ||
| Adam10 | a disintegrin and metallopeptidase domain 10 | 0.010 | ||
| Nans | N-acetylneuraminic acid synthase (sialic acid synthase) | 0.010 | ||
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.010 | ||
| Chsy1 | chondroitin sulfate synthase 1 | 0.010 | ||
| Atad5 | ATPase family, AAA domain containing 5 | 0.010 | ||
| Ccr2 | chemokine (C-C motif) receptor 2 | 0.010 | ||
| Ppp1r12a | protein phosphatase 1, regulatory (inhibitor) subunit 12A | 0.010 | ||
| Lasp1 | LIM and SH3 protein 1 | 0.010 | ||
| Cntn1 | contactin 1 | 0.010 | ||
| Ptp4a2 | protein tyrosine phosphatase 4a2 | 0.010 | ||
| Fubp3 | far upstream element (FUSE) binding protein 3 | 0.010 | ||
| Ttk | Ttk protein kinase | 0.010 |