IMP: Integrative Multi-species Prediction

Mus musculus

9 genes annotated in mouse

negative regulation of purine nucleotide catabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of purine nucleotide catabolic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "negative regulation of purine nucleotide catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Srsf9	serine/arginine-rich splicing factor 9	0.965
Spry4	sprouty homolog 4 (Drosophila)	0.895	Mouse
Lsm2	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.843
Thoc4	THO complex 4	0.541	Yeast
Mcm5	minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)	0.523
Ppp4c	protein phosphatase 4, catalytic subunit	0.490
Neurl1a	neuralized homolog 1A (Drosophila)	0.417
Refbp2	RNA and export factor binding protein 2	0.385	Yeast
Banf1	barrier to autointegration factor 1	0.338
Spry2	sprouty homolog 2 (Drosophila)	0.333
Tubb5	tubulin, beta 5	0.242
Prmt1	protein arginine N-methyltransferase 1	0.241
Fbl	fibrillarin	0.189
Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.184
Mcm3	minichromosome maintenance deficient 3 (S. cerevisiae)	0.183
Spry1	sprouty homolog 1 (Drosophila)	0.182
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.163
Ptma	prothymosin alpha	0.151
Vegfa	vascular endothelial growth factor A	0.130
Eif4a1	eukaryotic translation initiation factor 4A1	0.128
Tomm40	translocase of outer mitochondrial membrane 40 homolog (yeast)	0.120
Hnrnpab	heterogeneous nuclear ribonucleoprotein A/B	0.105
Cdt1	chromatin licensing and DNA replication factor 1	0.094
Uhrf1	ubiquitin-like, containing PHD and RING finger domains, 1	0.092
Arpc4	actin related protein 2/3 complex, subunit 4	0.090
Pfn1	profilin 1	0.082
Hnrnpm	heterogeneous nuclear ribonucleoprotein M	0.081
Epas1	endothelial PAS domain protein 1	0.077
Siah2	seven in absentia 2	0.075
Rcc2	regulator of chromosome condensation 2	0.074
Adcy9	adenylate cyclase 9	0.073
Rab5a	RAB5A, member RAS oncogene family	0.068
Kif1b	kinesin family member 1B	0.061
Cpeb2	cytoplasmic polyadenylation element binding protein 2	0.060
Ranbp1	RAN binding protein 1	0.059
Arhgef7	Rho guanine nucleotide exchange factor (GEF7)	0.058
Cpeb4	cytoplasmic polyadenylation element binding protein 4	0.057	Mouse
Mcm7	minichromosome maintenance deficient 7 (S. cerevisiae)	0.056
Gipc1	GIPC PDZ domain containing family, member 1	0.056
Ppm1g	protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform	0.055
Stim2	stromal interaction molecule 2	0.054
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.053
Pcbp1	poly(rC) binding protein 1	0.052
Fgfr3	fibroblast growth factor receptor 3	0.050
Dlg1	discs, large homolog 1 (Drosophila)	0.050
Rfc5	replication factor C (activator 1) 5	0.047
Atp5b	ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit	0.045
P4htm	prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)	0.044
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.044
U2af1	U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1	0.043
Ptprn	protein tyrosine phosphatase, receptor type, N	0.043
Txn2	thioredoxin 2	0.039
Yap1	yes-associated protein 1	0.038
Rsl24d1	ribosomal L24 domain containing 1	0.036
Dab1	disabled homolog 1 (Drosophila)	0.036
Ppil1	peptidylprolyl isomerase (cyclophilin)-like 1	0.036
Sult4a1	sulfotransferase family 4A, member 1	0.036
Cdk4	cyclin-dependent kinase 4	0.035
Rb1cc1	RB1-inducible coiled-coil 1	0.034
Srm	spermidine synthase	0.034
Ubtf	upstream binding transcription factor, RNA polymerase I	0.033
Raf1	v-raf-leukemia viral oncogene 1	0.033
Tsc22d2	TSC22 domain family, member 2	0.033
Ppm1a	protein phosphatase 1A, magnesium dependent, alpha isoform	0.031
Itsn1	intersectin 1 (SH3 domain protein 1A)	0.031
Dnajb9	DnaJ (Hsp40) homolog, subfamily B, member 9	0.031
Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isoform	0.031
Rnf11	ring finger protein 11	0.030
H2afx	H2A histone family, member X	0.028
Tuba1b	tubulin, alpha 1B	0.028
Mbd3	methyl-CpG binding domain protein 3	0.027
Vars	valyl-tRNA synthetase	0.027
Cab39	calcium binding protein 39	0.026
Lmo7	LIM domain only 7	0.026
Gar1	GAR1 ribonucleoprotein homolog (yeast)	0.025
Cdc34	cell division cycle 34 homolog (S. cerevisiae)	0.025
Gsr	glutathione reductase	0.024
Timeless	timeless homolog (Drosophila)	0.024
Snrk	SNF related kinase	0.023
1110008P14Rik	RIKEN cDNA 1110008P14 gene	0.023
Josd2	Josephin domain containing 2	0.022
Sos2	son of sevenless homolog 2 (Drosophila)	0.022
Cpeb3	cytoplasmic polyadenylation element binding protein 3	0.022	Mouse
Pfdn2	prefoldin 2	0.022
Prkaa2	protein kinase, AMP-activated, alpha 2 catalytic subunit	0.022
Dag1	dystroglycan 1	0.021
Hivep1	human immunodeficiency virus type I enhancer binding protein 1	0.020
Eea1	early endosome antigen 1	0.020
Cks1b	CDC28 protein kinase 1b	0.020
Psat1	phosphoserine aminotransferase 1	0.020
Trak1	trafficking protein, kinesin binding 1	0.020
Yrdc	yrdC domain containing (E.coli)	0.019
Gm16517	predicted gene, Gm16517	0.019
Dohh	deoxyhypusine hydroxylase/monooxygenase	0.019
Tnnc1	troponin C, cardiac/slow skeletal	0.018
Tob1	transducer of ErbB-2.1	0.018
Kif21a	kinesin family member 21A	0.018
Mef2a	myocyte enhancer factor 2A	0.018
Arhgef11	Rho guanine nucleotide exchange factor (GEF) 11	0.018
Rb1	retinoblastoma 1	0.018
Trappc10	trafficking protein particle complex 10	0.018
Rpa2	replication protein A2	0.017
Pdpk1	3-phosphoinositide dependent protein kinase 1	0.017
Ank	progressive ankylosis	0.017
G3bp1	Ras-GTPase-activating protein SH3-domain binding protein 1	0.017
Hopx	HOP homeobox	0.016
Bhlhe40	basic helix-loop-helix family, member e40	0.016
Epn2	epsin 2	0.016
March6	membrane-associated ring finger (C3HC4) 6	0.016
Phldb2	pleckstrin homology-like domain, family B, member 2	0.016
Grk6	G protein-coupled receptor kinase 6	0.016
Golga4	golgi autoantigen, golgin subfamily a, 4	0.016
1810013L24Rik	RIKEN cDNA 1810013L24 gene	0.015
Fbxo11	F-box protein 11	0.015
Hipk3	homeodomain interacting protein kinase 3	0.015
Nuak1	NUAK family, SNF1-like kinase, 1	0.015
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.014
Atp5d	ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit	0.014
Hnrnpl	heterogeneous nuclear ribonucleoprotein L	0.014
Ptpra	protein tyrosine phosphatase, receptor type, A	0.014
Zbtb11	zinc finger and BTB domain containing 11	0.014
3110043O21Rik	RIKEN cDNA 3110043O21 gene	0.014
Rnf103	ring finger protein 103	0.014
Tmed9	transmembrane emp24 protein transport domain containing 9	0.014
Apln	apelin	0.014
Eif2s3x	eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked	0.014
Dtna	dystrobrevin alpha	0.013
Rac1	RAS-related C3 botulinum substrate 1	0.013
Zfp238	zinc finger protein 238	0.013
F3	coagulation factor III	0.013
Wfs1	Wolfram syndrome 1 homolog (human)	0.013
Hmga1-rs1	high mobility group AT-hook I, related sequence 1	0.013
Etv5	ets variant gene 5	0.013
Prnp	prion protein	0.013
Tjp2	tight junction protein 2	0.013
Hmgn1	high mobility group nucleosomal binding domain 1	0.012
Spred1	sprouty protein with EVH-1 domain 1, related sequence	0.012
Cdca7	cell division cycle associated 7	0.012
Rabgef1	RAB guanine nucleotide exchange factor (GEF) 1	0.012
Tsen34	tRNA splicing endonuclease 34 homolog (S. cerevisiae)	0.012
Sec23a	SEC23A (S. cerevisiae)	0.012
Ptges2	prostaglandin E synthase 2	0.012
Clcn3	chloride channel 3	0.012
Ssr3	signal sequence receptor, gamma	0.012
Samd8	sterile alpha motif domain containing 8	0.012
Zcchc14	zinc finger, CCHC domain containing 14	0.012
Spry3	sprouty homolog 3 (Drosophila)	0.012
Rhob	ras homolog gene family, member B	0.011
Clcn4-2	chloride channel 4-2	0.011
Fam134b	family with sequence similarity 134, member B	0.011
Rock2	Rho-associated coiled-coil containing protein kinase 2	0.011
Dnmt1	DNA methyltransferase (cytosine-5) 1	0.011
Anp32b	acidic (leucine-rich) nuclear phosphoprotein 32 family, member B	0.011
Smad7	MAD homolog 7 (Drosophila)	0.011
Wwtr1	WW domain containing transcription regulator 1	0.011
Rhoq	ras homolog gene family, member Q	0.011
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.011
Fis1	fission 1 (mitochondrial outer membrane) homolog (yeast)	0.011
A630007B06Rik	RIKEN cDNA A630007B06 gene	0.011
Gsk3b	glycogen synthase kinase 3 beta	0.011
Zfand5	zinc finger, AN1-type domain 5	0.011
Cdc37	cell division cycle 37 homolog (S. cerevisiae)	0.011
Tssc4	tumor-suppressing subchromosomal transferable fragment 4	0.011
Nxt1	NTF2-related export protein 1	0.011
Tjp1	tight junction protein 1	0.011
Rab6	RAB6, member RAS oncogene family	0.011
Amotl2	angiomotin-like 2	0.011
Ap2a1	adaptor protein complex AP-2, alpha 1 subunit	0.010
Arhgdig	Rho GDP dissociation inhibitor (GDI) gamma	0.010
2310061I04Rik	RIKEN cDNA 2310061I04 gene	0.010
Zbtb7a	zinc finger and BTB domain containing 7a	0.010
Cfl1	cofilin 1, non-muscle	0.010
Vangl2	vang-like 2 (van gogh, Drosophila)	0.010
Timm13	translocase of inner mitochondrial membrane 13 homolog (yeast)	0.010