IMP
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endothelial tube morphogenesis
The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "endothelial tube morphogenesis"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Notch1 | Notch gene homolog 1 (Drosophila) | 1.000 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.994 | ||
| Shh | sonic hedgehog | 0.987 | ||
| Psen1 | presenilin 1 | 0.986 | ||
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.979 | ||
| Fgfr1 | fibroblast growth factor receptor 1 | 0.968 | ||
| Dll1 | delta-like 1 (Drosophila) | 0.964 | Mouse | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.883 | ||
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.837 | ||
| Foxc1 | forkhead box C1 | 0.836 | ||
| Rbpj | recombination signal binding protein for immunoglobulin kappa J region | 0.780 | ||
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.692 | ||
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.595 | ||
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.514 | ||
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.466 | ||
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.462 | ||
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.459 | ||
| Foxg1 | forkhead box G1 | 0.409 | ||
| Pten | phosphatase and tensin homolog | 0.367 | ||
| Dll4 | delta-like 4 (Drosophila) | 0.348 | ||
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.320 | ||
| Vegfa | vascular endothelial growth factor A | 0.290 | ||
| Rb1 | retinoblastoma 1 | 0.272 | ||
| Efnb2 | ephrin B2 | 0.264 | ||
| Pax3 | paired box gene 3 | 0.230 | ||
| Ednra | endothelin receptor type A | 0.193 | ||
| Jag1 | jagged 1 | 0.184 | Mouse | |
| Meox2 | mesenchyme homeobox 2 | 0.168 | ||
| Tbx1 | T-box 1 | 0.160 | ||
| Eng | endoglin | 0.154 | ||
| Prrx2 | paired related homeobox 2 | 0.143 | ||
| Foxc2 | forkhead box C2 | 0.135 | ||
| Lfng | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 0.132 | ||
| Gata4 | GATA binding protein 4 | 0.126 | ||
| Rarg | retinoic acid receptor, gamma | 0.122 | ||
| Prrx1 | paired related homeobox 1 | 0.118 | ||
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.106 | Human | |
| Neurl1a | neuralized homolog 1A (Drosophila) | 0.101 | ||
| Tcte3 | t-complex-associated testis expressed 3 | 0.095 | ||
| Cited2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.095 | ||
| Cdc42 | cell division cycle 42 homolog (S. cerevisiae) | 0.087 | ||
| Hoxa9 | homeobox A9 | 0.086 | ||
| Rarb | retinoic acid receptor, beta | 0.085 | ||
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.084 | ||
| Gata3 | GATA binding protein 3 | 0.083 | ||
| Sox2 | SRY-box containing gene 2 | 0.082 | ||
| Psen2 | presenilin 2 | 0.073 | ||
| Pax2 | paired box gene 2 | 0.071 | ||
| Hoxa1 | homeobox A1 | 0.069 | ||
| Hoxa5 | homeobox A5 | 0.068 | ||
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.068 | ||
| Hoxa2 | homeobox A2 | 0.068 | ||
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.062 | ||
| Rac1 | RAS-related C3 botulinum substrate 1 | 0.057 | ||
| Gpc3 | glypican 3 | 0.056 | ||
| Erbb2ip | Erbb2 interacting protein | 0.054 | ||
| Ptk7 | PTK7 protein tyrosine kinase 7 | 0.054 | ||
| Wdr1 | WD repeat domain 1 | 0.053 | ||
| Tcf21 | transcription factor 21 | 0.051 | ||
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.047 | ||
| Hes5 | hairy and enhancer of split 5 (Drosophila) | 0.046 | ||
| Msx1 | homeobox, msh-like 1 | 0.046 | ||
| Axin1 | axin 1 | 0.046 | ||
| Lama5 | laminin, alpha 5 | 0.045 | ||
| Tbx18 | T-box18 | 0.044 | ||
| Fgf8 | fibroblast growth factor 8 | 0.044 | ||
| Rxra | retinoid X receptor alpha | 0.042 | ||
| Nrarp | Notch-regulated ankyrin repeat protein | 0.041 | ||
| Ece1 | endothelin converting enzyme 1 | 0.039 | ||
| Nr2f2 | nuclear receptor subfamily 2, group F, member 2 | 0.038 | ||
| Nog | noggin | 0.038 | ||
| Tcfap2a | transcription factor AP-2, alpha | 0.037 | ||
| Fgfr3 | fibroblast growth factor receptor 3 | 0.037 | ||
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.037 | ||
| Mobkl1b | MOB1, Mps One Binder kinase activator-like 1B (yeast) | 0.036 | ||
| Wipf1 | WAS/WASL interacting protein family, member 1 | 0.036 | ||
| Sox18 | SRY-box containing gene 18 | 0.036 | ||
| Jag2 | jagged 2 | 0.034 | Mouse | |
| Sh3bgrl3 | SH3 domain binding glutamic acid-rich protein-like 3 | 0.034 | ||
| Fgf10 | fibroblast growth factor 10 | 0.032 | ||
| Foxf1a | forkhead box F1a | 0.031 | ||
| Ywhaz | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.031 | ||
| Bmp7 | bone morphogenetic protein 7 | 0.030 | ||
| Twist2 | twist homolog 2 (Drosophila) | 0.030 | ||
| Tgfb2 | transforming growth factor, beta 2 | 0.030 | ||
| Tcf15 | transcription factor 15 | 0.029 | ||
| Nrp1 | neuropilin 1 | 0.029 | ||
| Cdh5 | cadherin 5 | 0.029 | ||
| Sema3f | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F | 0.029 | ||
| Apc | adenomatosis polyposis coli | 0.028 | ||
| Kdr | kinase insert domain protein receptor | 0.028 | ||
| Gata6 | GATA binding protein 6 | 0.028 | ||
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.027 | ||
| Cldn5 | claudin 5 | 0.027 | ||
| Tbx10 | T-box 10 | 0.027 | ||
| Egfr | epidermal growth factor receptor | 0.027 | ||
| Zfp651 | zinc finger protein 651 | 0.027 | ||
| Ptpn14 | protein tyrosine phosphatase, non-receptor type 14 | 0.027 | ||
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.026 | ||
| Wnt4 | wingless-related MMTV integration site 4 | 0.026 | ||
| Pdgfb | platelet derived growth factor, B polypeptide | 0.026 | ||
| Bcl10 | B-cell leukemia/lymphoma 10 | 0.026 | ||
| Notch3 | Notch gene homolog 3 (Drosophila) | 0.026 | ||
| Acvr1 | activin A receptor, type 1 | 0.026 | ||
| Apaf1 | apoptotic peptidase activating factor 1 | 0.025 | ||
| Bcl6b | B-cell CLL/lymphoma 6, member B | 0.025 | ||
| Vasp | vasodilator-stimulated phosphoprotein | 0.025 | ||
| Immt | inner membrane protein, mitochondrial | 0.024 | ||
| Adcy4 | adenylate cyclase 4 | 0.023 | ||
| Trp73 | transformation related protein 73 | 0.023 | ||
| Tpm4 | tropomyosin 4 | 0.023 | ||
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.023 | ||
| Klf3 | Kruppel-like factor 3 (basic) | 0.023 | ||
| Twsg1 | twisted gastrulation homolog 1 (Drosophila) | 0.022 | ||
| Meox1 | mesenchyme homeobox 1 | 0.022 | ||
| Sox7 | SRY-box containing gene 7 | 0.022 | ||
| Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.022 | ||
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.022 | ||
| Rara | retinoic acid receptor, alpha | 0.022 | ||
| Kcnq1 | potassium voltage-gated channel, subfamily Q, member 1 | 0.021 | ||
| Tmod3 | tropomodulin 3 | 0.021 | ||
| Hoxa11 | homeobox A11 | 0.020 | ||
| Sp6 | trans-acting transcription factor 6 | 0.020 | ||
| Aplnr | apelin receptor | 0.019 | ||
| Vcl | vinculin | 0.019 | ||
| Sgpl1 | sphingosine phosphate lyase 1 | 0.019 | ||
| Gata2 | GATA binding protein 2 | 0.019 | ||
| She | src homology 2 domain-containing transforming protein E | 0.019 | ||
| Epas1 | endothelial PAS domain protein 1 | 0.019 | ||
| Fgd5 | FYVE, RhoGEF and PH domain containing 5 | 0.019 | ||
| Ptf1a | pancreas specific transcription factor, 1a | 0.019 | ||
| Six4 | sine oculis-related homeobox 4 homolog (Drosophila) | 0.018 | ||
| Hoxb4 | homeobox B4 | 0.018 | ||
| Obsl1 | obscurin-like 1 | 0.018 | ||
| Tgfa | transforming growth factor alpha | 0.018 | ||
| Ager | advanced glycosylation end product-specific receptor | 0.018 | ||
| Efnb1 | ephrin B1 | 0.018 | ||
| Tead4 | TEA domain family member 4 | 0.018 | ||
| Pds5a | PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae) | 0.018 | ||
| Dlx5 | distal-less homeobox 5 | 0.017 | ||
| Zcchc11 | zinc finger, CCHC domain containing 11 | 0.017 | ||
| Clic3 | chloride intracellular channel 3 | 0.017 | ||
| Ctnna1 | catenin (cadherin associated protein), alpha 1 | 0.017 | ||
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.017 | ||
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.016 | ||
| Sox17 | SRY-box containing gene 17 | 0.016 | ||
| Sox9 | SRY-box containing gene 9 | 0.016 | ||
| Pofut1 | protein O-fucosyltransferase 1 | 0.016 | ||
| Ccnd1 | cyclin D1 | 0.016 | ||
| Sema5b | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B | 0.016 | ||
| Pecam1 | platelet/endothelial cell adhesion molecule 1 | 0.016 | ||
| Numb | numb gene homolog (Drosophila) | 0.016 | ||
| Adam17 | a disintegrin and metallopeptidase domain 17 | 0.016 | ||
| Ggta1 | glycoprotein galactosyltransferase alpha 1, 3 | 0.015 | ||
| Arvcf | armadillo repeat gene deleted in velo-cardio-facial syndrome | 0.015 | ||
| Fis1 | fission 1 (mitochondrial outer membrane) homolog (yeast) | 0.015 | ||
| Litaf | LPS-induced TN factor | 0.015 | ||
| Tbx4 | T-box 4 | 0.015 | ||
| Tlx3 | T-cell leukemia, homeobox 3 | 0.015 | ||
| Mesp2 | mesoderm posterior 2 | 0.015 | ||
| Cd44 | CD44 antigen | 0.015 | ||
| Ndst1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.015 | ||
| Gsk3b | glycogen synthase kinase 3 beta | 0.015 | ||
| Rasip1 | Ras interacting protein 1 | 0.015 | ||
| Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.015 | ||
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.014 | ||
| Yap1 | yes-associated protein 1 | 0.014 | ||
| Slc12a2 | solute carrier family 12, member 2 | 0.014 | ||
| Pou4f3 | POU domain, class 4, transcription factor 3 | 0.014 | ||
| Hoxa10 | homeobox A10 | 0.014 | ||
| Ucn | urocortin | 0.014 | ||
| Bnc1 | basonuclin 1 | 0.014 | ||
| Rdh10 | retinol dehydrogenase 10 (all-trans) | 0.014 | ||
| Foxn4 | forkhead box N4 | 0.014 | ||
| Anxa5 | annexin A5 | 0.014 | ||
| Tbx2 | T-box 2 | 0.013 | ||
| Bcam | basal cell adhesion molecule | 0.013 | ||
| Smad4 | MAD homolog 4 (Drosophila) | 0.013 | ||
| Chrd | chordin | 0.013 | ||
| Egfl7 | EGF-like domain 7 | 0.013 | ||
| Itga3 | integrin alpha 3 | 0.013 | ||
| Kcnh2 | potassium voltage-gated channel, subfamily H (eag-related), member 2 | 0.013 | ||
| Apln | apelin | 0.013 | ||
| Jmjd1c | jumonji domain containing 1C | 0.013 | ||
| Smo | smoothened homolog (Drosophila) | 0.013 | ||
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.013 | ||
| Wnt3a | wingless-related MMTV integration site 3A | 0.013 | ||
| Mcam | melanoma cell adhesion molecule | 0.013 | ||
| Lims1 | LIM and senescent cell antigen-like domains 1 | 0.013 | ||
| Tgfbr2 | transforming growth factor, beta receptor II | 0.012 | ||
| Ppp1ca | protein phosphatase 1, catalytic subunit, alpha isoform | 0.012 | ||
| Irx3 | Iroquois related homeobox 3 (Drosophila) | 0.012 | ||
| Edn3 | endothelin 3 | 0.012 | ||
| Trp53 | transformation related protein 53 | 0.012 | ||
| Wt1 | Wilms tumor 1 homolog | 0.012 | ||
| Cd97 | CD97 antigen | 0.012 | ||
| Wnt9b | wingless-type MMTV integration site 9B | 0.012 | ||
| Fli1 | Friend leukemia integration 1 | 0.012 | ||
| Pcdh12 | protocadherin 12 | 0.012 | ||
| Ptrf | polymerase I and transcript release factor | 0.012 | ||
| Edn1 | endothelin 1 | 0.012 | ||
| Rpl38 | ribosomal protein L38 | 0.012 | ||
| Hoxa3 | homeobox A3 | 0.012 | ||
| Lrp2 | low density lipoprotein receptor-related protein 2 | 0.012 | ||
| Epb4.1l2 | erythrocyte protein band 4.1-like 2 | 0.011 | ||
| Sltm | SAFB-like, transcription modulator | 0.011 | ||
| Clic4 | chloride intracellular channel 4 (mitochondrial) | 0.011 | ||
| Wnt11 | wingless-related MMTV integration site 11 | 0.011 | ||
| Lox | lysyl oxidase | 0.011 | ||
| Mfng | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 0.011 | ||
| Padi3 | peptidyl arginine deiminase, type III | 0.011 | ||
| App | amyloid beta (A4) precursor protein | 0.011 | ||
| Epha2 | Eph receptor A2 | 0.011 | ||
| Meis2 | Meis homeobox 2 | 0.011 | ||
| Hoxb5 | homeobox B5 | 0.011 | ||
| Nr2f1 | nuclear receptor subfamily 2, group F, member 1 | 0.011 | ||
| Bcan | brevican | 0.011 | ||
| Hoxa13 | homeobox A13 | 0.011 | ||
| Cnn2 | calponin 2 | 0.011 | ||
| Fzd1 | frizzled homolog 1 (Drosophila) | 0.011 | ||
| Snai1 | snail homolog 1 (Drosophila) | 0.011 | ||
| Tie1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 0.011 | ||
| Hr | hairless | 0.011 | ||
| Zmym5 | zinc finger, MYM-type 5 | 0.011 | ||
| Foxa2 | forkhead box A2 | 0.011 | ||
| Rai12 | retinoic acid induced 12 | 0.011 | ||
| Myl7 | myosin, light polypeptide 7, regulatory | 0.011 | ||
| Sox13 | SRY-box containing gene 13 | 0.010 | ||
| Otx1 | orthodenticle homolog 1 (Drosophila) | 0.010 | ||
| Zfp800 | zinc finger protein 800 | 0.010 | ||
| Zfpm2 | zinc finger protein, multitype 2 | 0.010 | ||
| Myo6 | myosin VI | 0.010 | ||
| Rbms1 | RNA binding motif, single stranded interacting protein 1 | 0.010 | ||
| Tgif1 | TGFB-induced factor homeobox 1 | 0.010 | ||
| Ext1 | exostoses (multiple) 1 | 0.010 | ||
| Cpne1 | copine I | 0.010 | ||
| Col7a1 | collagen, type VII, alpha 1 | 0.010 | ||
| Slurp1 | secreted Ly6/Plaur domain containing 1 | 0.010 |