IMP: Integrative Multi-species Prediction

Mus musculus

85 genes annotated in mouse

i kappab kinase nf kappab signaling

The process in which a signal is passed on to downstream components within the cell through the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subunits IKKalpha and/or IKKbeta, and the regulatory scaffold protein NEMO) and ends with the regulation of transcription of target genes by NF-kappaB. In a resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "i kappab kinase nf kappab signaling"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "i kappab kinase nf kappab signaling" (in gray)

Name	Description	Probability	Func Analog Organism
Tlr4	toll-like receptor 4	1.000
Tnf	tumor necrosis factor	1.000
Myd88	myeloid differentiation primary response gene 88	1.000
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	1.000	Mouse
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	1.000	Human
Traf6	TNF receptor-associated factor 6	1.000
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.999	Mouse
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.999	Mouse
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.999
Casp1	caspase 1	0.999
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.999
Ikbkg	inhibitor of kappaB kinase gamma	0.999	Human Zebrafish
Il1r1	interleukin 1 receptor, type I	0.998	Mouse
Lyz2	lysozyme 2	0.998
Cd44	CD44 antigen	0.994
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.989
Lta	lymphotoxin A	0.985	Mouse
Ticam1	toll-like receptor adaptor molecule 1	0.985
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.984
Cd40	CD40 antigen	0.978	Human
Ccl2	chemokine (C-C motif) ligand 2	0.973
Ikbkb	inhibitor of kappaB kinase beta	0.970
Ctnnb1	catenin (cadherin associated protein), beta 1	0.968
Casp8	caspase 8	0.961	Human Mouse
Birc3	baculoviral IAP repeat-containing 3	0.950
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.946
Fas	Fas (TNF receptor superfamily member 6)	0.944
Ikzf1	IKAROS family zinc finger 1	0.929
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.929	Mouse
Cd19	CD19 antigen	0.926
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.922
Cd28	CD28 antigen	0.874
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.865
Il1b	interleukin 1 beta	0.856
Stat3	signal transducer and activator of transcription 3	0.845
Bcl3	B-cell leukemia/lymphoma 3	0.824	Human
Hif1a	hypoxia inducible factor 1, alpha subunit	0.811
S100a6	S100 calcium binding protein A6 (calcyclin)	0.808
Cyld	cylindromatosis (turban tumor syndrome)	0.805	Human
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.795
Pim1	proviral integration site 1	0.791	Mouse
Clec4d	C-type lectin domain family 4, member d	0.746	Mouse
Pten	phosphatase and tensin homolog	0.744
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.743	Human Rat
Tbk1	TANK-binding kinase 1	0.732	Human Mouse
Clec4e	C-type lectin domain family 4, member e	0.720	Mouse
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.715
Cd14	CD14 antigen	0.698
Il10	interleukin 10	0.679
Ifng	interferon gamma	0.672
Casp12	caspase 12	0.656	Mouse
Nlrp3	NLR family, pyrin domain containing 3	0.655	Human Mouse
Il18rap	interleukin 18 receptor accessory protein	0.650	Mouse
Traf2	TNF receptor-associated factor 2	0.649	Mouse
Il7	interleukin 7	0.617
Icos	inducible T-cell co-stimulator	0.613
Socs1	suppressor of cytokine signaling 1	0.608
Chuk	conserved helix-loop-helix ubiquitous kinase	0.606
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.571
Ptprc	protein tyrosine phosphatase, receptor type, C	0.529
Ptk2	PTK2 protein tyrosine kinase 2	0.526
Cxcl13	chemokine (C-X-C motif) ligand 13	0.521
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.507
Zfp36	zinc finger protein 36	0.506
Ifnar1	interferon (alpha and beta) receptor 1	0.505
Irf1	interferon regulatory factor 1	0.500
Il6	interleukin 6	0.484
Il1rn	interleukin 1 receptor antagonist	0.480	Mouse
Ccr6	chemokine (C-C motif) receptor 6	0.479
Kiss1	KiSS-1 metastasis-suppressor	0.477
Sqstm1	sequestosome 1	0.457	Human
Ltb	lymphotoxin B	0.453
Ccr1	chemokine (C-C motif) receptor 1	0.447
Rnf31	ring finger protein 31	0.442
Cd86	CD86 antigen	0.442
Tcra	T-cell receptor alpha chain	0.438
Il2rg	interleukin 2 receptor, gamma chain	0.436
Mll5	myeloid/lymphoid or mixed-lineage leukemia 5	0.430
Edaradd	EDAR (ectodysplasin-A receptor)-associated death domain	0.413
Pxn	paxillin	0.412
Mavs	mitochondrial antiviral signaling protein	0.411	Human
Clec4n	C-type lectin domain family 4, member n	0.409
Tnip1	TNFAIP3 interacting protein 1	0.406
Traf3	TNF receptor-associated factor 3	0.406	Mouse
Csf1	colony stimulating factor 1 (macrophage)	0.405
Tlr2	toll-like receptor 2	0.401	Mouse
Slfn4	schlafen 4	0.392
Unc93b1	unc-93 homolog B1 (C. elegans)	0.389
Il2rb	interleukin 2 receptor, beta chain	0.382
Mvp	major vault protein	0.381
Ubc	ubiquitin C	0.380
Notch1	Notch gene homolog 1 (Drosophila)	0.371	Fly
Cav1	caveolin 1, caveolae protein	0.363
Trim21	tripartite motif-containing 21	0.357
Dok1	docking protein 1	0.354
Gbp5	guanylate binding protein 5	0.354
Cxcl2	chemokine (C-X-C motif) ligand 2	0.352
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.350	Mouse
Inpp5d	inositol polyphosphate-5-phosphatase D	0.347
Vim	vimentin	0.340
Tab2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.335	Human
Smad4	MAD homolog 4 (Drosophila)	0.328
Sharpin	SHANK-associated RH domain interacting protein	0.326
Irak4	interleukin-1 receptor-associated kinase 4	0.321	Human
Ptgfr	prostaglandin F receptor	0.313
Lepr	leptin receptor	0.311
Prkce	protein kinase C, epsilon	0.306
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.297	Fly
Nos2	nitric oxide synthase 2, inducible	0.296
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.295
Amhr2	anti-Mullerian hormone type 2 receptor	0.292
Atf2	activating transcription factor 2	0.286
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.283
Itch	itchy, E3 ubiquitin protein ligase	0.282
Traf3ip2	TRAF3 interacting protein 2	0.279
Flii	flightless I homolog (Drosophila)	0.275
Prkcd	protein kinase C, delta	0.266
Dll1	delta-like 1 (Drosophila)	0.265
Tcf3	transcription factor 3	0.262
Sykb	spleen tyrosine kinase	0.261
Cd209b	CD209b antigen	0.257	Mouse
Irak3	interleukin-1 receptor-associated kinase 3	0.253
Mefv	Mediterranean fever	0.252
Pim3	proviral integration site 3	0.249	Mouse
Cxcr5	chemokine (C-X-C motif) receptor 5	0.248
Ncr1	natural cytotoxicity triggering receptor 1	0.246
Fpr2	formyl peptide receptor 2	0.240
Pik3ap1	phosphoinositide-3-kinase adaptor protein 1	0.237
Trim30d	tripartite motif-containing 30D	0.234	Human
Blk	B lymphoid kinase	0.234	Mouse
C1qb	complement component 1, q subcomponent, beta polypeptide	0.233	Mouse
Cryab	crystallin, alpha B	0.226	Mouse
Fgf7	fibroblast growth factor 7	0.222
Crebbp	CREB binding protein	0.220
Aim2	absent in melanoma 2	0.216
Junb	Jun-B oncogene	0.211
Socs3	suppressor of cytokine signaling 3	0.207
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.207	Mouse
Smad1	MAD homolog 1 (Drosophila)	0.206
Edar	ectodysplasin-A receptor	0.206
Btk	Bruton agammaglobulinemia tyrosine kinase	0.202
Mapk1	mitogen-activated protein kinase 1	0.201
2310014H01Rik	RIKEN cDNA 2310014H01 gene	0.201
Wwtr1	WW domain containing transcription regulator 1	0.196
Htt	huntingtin	0.196
Ifngr1	interferon gamma receptor 1	0.196
Trim55	tripartite motif-containing 55	0.196
Stat1	signal transducer and activator of transcription 1	0.194	Human
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.193	Mouse
Ltbr	lymphotoxin B receptor	0.193	Human
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.190
Ccl4	chemokine (C-C motif) ligand 4	0.185
Il1r2	interleukin 1 receptor, type II	0.184	Mouse
Il22	interleukin 22	0.184
Clock	circadian locomotor output cycles kaput	0.183
Ldb3	LIM domain binding 3	0.181
Tnfsf10	tumor necrosis factor (ligand) superfamily, member 10	0.178	Human Mouse
Bcl10	B-cell leukemia/lymphoma 10	0.177
Plekhg2	pleckstrin homology domain containing, family G (with RhoGef domain) member 2	0.177
Mmp8	matrix metallopeptidase 8	0.174
Il13ra1	interleukin 13 receptor, alpha 1	0.174
Traf1	TNF receptor-associated factor 1	0.171	Mouse
Lif	leukemia inhibitory factor	0.171
Ly96	lymphocyte antigen 96	0.169
Il1f9	interleukin 1 family, member 9	0.169
Ms4a6d	membrane-spanning 4-domains, subfamily A, member 6D	0.169
Actn2	actinin alpha 2	0.168
Il15	interleukin 15	0.168
Cd96	CD96 antigen	0.167
Ggt5	gamma-glutamyltransferase 5	0.167
Fgd3	FYVE, RhoGEF and PH domain containing 3	0.165
Rb1	retinoblastoma 1	0.165
Spib	Spi-B transcription factor (Spi-1/PU.1 related)	0.164
Cd4	CD4 antigen	0.161
Notch2	Notch gene homolog 2 (Drosophila)	0.161	Fly
Klf7	Kruppel-like factor 7 (ubiquitous)	0.160
Lair1	leukocyte-associated Ig-like receptor 1	0.159
Per2	period homolog 2 (Drosophila)	0.159
Src	Rous sarcoma oncogene	0.158	Mouse
Zfp362	zinc finger protein 362	0.158
Peli1	pellino 1	0.155
Ccr9	chemokine (C-C motif) receptor 9	0.154
Tlr6	toll-like receptor 6	0.153	Human Mouse
Jak2	Janus kinase 2	0.153
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.150
Plcg2	phospholipase C, gamma 2	0.145
Cd33	CD33 antigen	0.145
Bhlhe40	basic helix-loop-helix family, member e40	0.144
Trim30a	tripartite motif-containing 30A	0.142	Human
Slfn2	schlafen 2	0.142
Ccr7	chemokine (C-C motif) receptor 7	0.142
Orm2	orosomucoid 2	0.141
Cd5	CD5 antigen	0.141
H2-Eb1	histocompatibility 2, class II antigen E beta	0.139
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.138
Skor1	SKI family transcriptional corepressor 1	0.137
Spsb1	splA/ryanodine receptor domain and SOCS box containing 1	0.137
Il4ra	interleukin 4 receptor, alpha	0.136
Adam17	a disintegrin and metallopeptidase domain 17	0.135
Card11	caspase recruitment domain family, member 11	0.134
Kcnj6	potassium inwardly-rectifying channel, subfamily J, member 6	0.133
Cd209g	CD209g antigen	0.131
Card9	caspase recruitment domain family, member 9	0.130	Human Mouse Rat
Fcgr1	Fc receptor, IgG, high affinity I	0.130
Tlr5	toll-like receptor 5	0.129	Mouse
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.126
Fadd	Fas (TNFRSF6)-associated via death domain	0.124	Human
Map4k4	mitogen-activated protein kinase kinase kinase kinase 4	0.124
Ywhaq	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.123
Rras	Harvey rat sarcoma oncogene, subgroup R	0.123
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.122
Nhlh2	nescient helix loop helix 2	0.122
Tgif1	TGFB-induced factor homeobox 1	0.121
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.119
AF251705	cDNA sequence AF251705	0.119
Pparg	peroxisome proliferator activated receptor gamma	0.119
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.119
Ralb	v-ral simian leukemia viral oncogene homolog B (ras related)	0.117
Becn1	beclin 1, autophagy related	0.116
Cd300ld	CD300 molecule-like family member d	0.116
Bcar1	breast cancer anti-estrogen resistance 1	0.116
S100a10	S100 calcium binding protein A10 (calpactin)	0.116
Cybb	cytochrome b-245, beta polypeptide	0.116
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.116
Rel	reticuloendotheliosis oncogene	0.115	Human Mouse
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.113
Fndc7	fibronectin type III domain containing 7	0.112
Tnfaip1	tumor necrosis factor, alpha-induced protein 1 (endothelial)	0.112
Rpe65	retinal pigment epithelium 65	0.111
Htra3	HtrA serine peptidase 3	0.111
Tgm2	transglutaminase 2, C polypeptide	0.111
Pdpk1	3-phosphoinositide dependent protein kinase 1	0.111	Human
Tnni2	troponin I, skeletal, fast 2	0.110
Ccbp2	chemokine binding protein 2	0.109
Rhbdf1	rhomboid family 1 (Drosophila)	0.108
Psen2	presenilin 2	0.108
Phlda3	pleckstrin homology-like domain, family A, member 3	0.108
Cd8a	CD8 antigen, alpha chain	0.108
Il10ra	interleukin 10 receptor, alpha	0.107
Ctsw	cathepsin W	0.107
Eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2	0.107
Gbp7	guanylate binding protein 7	0.106
Emp3	epithelial membrane protein 3	0.106
Pvrl2	poliovirus receptor-related 2	0.105
Nmi	N-myc (and STAT) interactor	0.104
Jak3	Janus kinase 3	0.104
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.104
Esr1	estrogen receptor 1 (alpha)	0.103	Human
Parp14	poly (ADP-ribose) polymerase family, member 14	0.103
Ddx58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.102
Tax1bp1	Tax1 (human T-cell leukemia virus type I) binding protein 1	0.102
Fyn	Fyn proto-oncogene	0.101
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.100
Marco	macrophage receptor with collagenous structure	0.100
C3ar1	complement component 3a receptor 1	0.098
Adam8	a disintegrin and metallopeptidase domain 8	0.098
Pla2r1	phospholipase A2 receptor 1	0.097
Lcp2	lymphocyte cytosolic protein 2	0.097
March7	membrane-associated ring finger (C3HC4) 7	0.097
Klra9	killer cell lectin-like receptor subfamily A, member 9	0.097
S100a9	S100 calcium binding protein A9 (calgranulin B)	0.096
Selp	selectin, platelet	0.096
S100a1	S100 calcium binding protein A1	0.096
Slpi	secretory leukocyte peptidase inhibitor	0.095
Il17ra	interleukin 17 receptor A	0.095
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.095
Zc3h12a	zinc finger CCCH type containing 12A	0.094
Ubd	ubiquitin D	0.094
Dtx1	deltex 1 homolog (Drosophila)	0.094
Spp1	secreted phosphoprotein 1	0.094
Plec	plectin	0.093
Tnfrsf19	tumor necrosis factor receptor superfamily, member 19	0.092
Msr1	macrophage scavenger receptor 1	0.092
Rbl1	retinoblastoma-like 1 (p107)	0.091
Tpm4	tropomyosin 4	0.091
Sfpi1	SFFV proviral integration 1	0.091
Ccl8	chemokine (C-C motif) ligand 8	0.090
Slamf8	SLAM family member 8	0.090
Vdr	vitamin D receptor	0.089
Pycard	PYD and CARD domain containing	0.089	Human
Gadd45b	growth arrest and DNA-damage-inducible 45 beta	0.089
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.088
Il17a	interleukin 17A	0.087
Eda	ectodysplasin-A	0.087
Ahr	aryl-hydrocarbon receptor	0.087
Itgav	integrin alpha V	0.087
Ccr3	chemokine (C-C motif) receptor 3	0.086
Lemd2	LEM domain containing 2	0.086
Hmox1	heme oxygenase (decycling) 1	0.086	Human
Pou2af1	POU domain, class 2, associating factor 1	0.085
Cry2	cryptochrome 2 (photolyase-like)	0.085
Pla2g4a	phospholipase A2, group IVA (cytosolic, calcium-dependent)	0.085
Id2	inhibitor of DNA binding 2	0.085
Skil	SKI-like	0.085
Myc	myelocytomatosis oncogene	0.084
Adamdec1	ADAM-like, decysin 1	0.084
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.083
Plaur	plasminogen activator, urokinase receptor	0.083
Tcirg1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3	0.083
Sgcg	sarcoglycan, gamma (dystrophin-associated glycoprotein)	0.083
Il12rb2	interleukin 12 receptor, beta 2	0.083
Tax1bp3	Tax1 (human T-cell leukemia virus type I) binding protein 3	0.083
Tgfb1	transforming growth factor, beta 1	0.082
Wnt10b	wingless related MMTV integration site 10b	0.082
Foxo1	forkhead box O1	0.082
Itk	IL2-inducible T-cell kinase	0.081
Xcr1	chemokine (C motif) receptor 1	0.081
Trim12a	tripartite motif-containing 12A	0.081	Human
Siglece	sialic acid binding Ig-like lectin E	0.081
Plscr1	phospholipid scramblase 1	0.080
Ptgs2	prostaglandin-endoperoxide synthase 2	0.080	Rat
Hgf	hepatocyte growth factor	0.080
Stx11	syntaxin 11	0.080
Ncor1	nuclear receptor co-repressor 1	0.079
Pilra	paired immunoglobin-like type 2 receptor alpha	0.079
Lhx3	LIM homeobox protein 3	0.079
Mapk8	mitogen-activated protein kinase 8	0.079
Cd209c	CD209c antigen	0.079	Mouse
Irak1	interleukin-1 receptor-associated kinase 1	0.079	Human
Tox	thymocyte selection-associated high mobility group box	0.079
Ptf1a	pancreas specific transcription factor, 1a	0.078
Errfi1	ERBB receptor feedback inhibitor 1	0.078
Cux1	cut-like homeobox 1	0.077
Lrp10	low-density lipoprotein receptor-related protein 10	0.077
Reln	reelin	0.077
Cdk4	cyclin-dependent kinase 4	0.077
Ptgir	prostaglandin I receptor (IP)	0.077
Hspa1b	heat shock protein 1B	0.076
Mrc1	mannose receptor, C type 1	0.076
Egfr	epidermal growth factor receptor	0.075
Sult5a1	sulfotransferase family 5A, member 1	0.075
Foxn1	forkhead box N1	0.075
Bach1	BTB and CNC homology 1	0.074
Il18r1	interleukin 18 receptor 1	0.074
Zp2	zona pellucida glycoprotein 2	0.074
Dab1	disabled homolog 1 (Drosophila)	0.074
Il2	interleukin 2	0.074
Wasf2	WAS protein family, member 2	0.074
Osmr	oncostatin M receptor	0.073
Vasp	vasodilator-stimulated phosphoprotein	0.073
Il6st	interleukin 6 signal transducer	0.073
Nfkbie	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.073
Pim2	proviral integration site 2	0.073
Cr2	complement receptor 2	0.073
Gpr132	G protein-coupled receptor 132	0.073
Cyr61	cysteine rich protein 61	0.073
Brd2	bromodomain containing 2	0.073
Nphp4	nephronophthisis 4 (juvenile) homolog (human)	0.072
Mmp12	matrix metallopeptidase 12	0.072
Scaf8	SR-related CTD-associated factor 8	0.072
Lck	lymphocyte protein tyrosine kinase	0.072	Mouse
Rac1	RAS-related C3 botulinum substrate 1	0.072
Ep300	E1A binding protein p300	0.072
Gjb2	gap junction protein, beta 2	0.072
Rhog	ras homolog gene family, member G	0.072
Ccl24	chemokine (C-C motif) ligand 24	0.072
Gnrh1	gonadotropin releasing hormone 1	0.071
Ar	androgen receptor	0.071
Rbms1	RNA binding motif, single stranded interacting protein 1	0.071
Trip6	thyroid hormone receptor interactor 6	0.071	Human Mouse
Fpr1	formyl peptide receptor 1	0.070
Rbck1	RanBP-type and C3HC4-type zinc finger containing 1	0.070
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.070
Rasgrp1	RAS guanyl releasing protein 1	0.070
Cysltr1	cysteinyl leukotriene receptor 1	0.070
Il4	interleukin 4	0.070
C3	complement component 3	0.069
Plau	plasminogen activator, urokinase	0.069
Casp3	caspase 3	0.069	Mouse
Hace1	HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1	0.069
Syngap1	synaptic Ras GTPase activating protein 1 homolog (rat)	0.069
N4bp1	NEDD4 binding protein 1	0.069
Asprv1	aspartic peptidase, retroviral-like 1	0.069
Csnk1e	casein kinase 1, epsilon	0.069
Rhoc	ras homolog gene family, member C	0.069	Human
Mcm4	minichromosome maintenance deficient 4 homolog (S. cerevisiae)	0.068
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2	0.068
Anxa2	annexin A2	0.068
Cnn3	calponin 3, acidic	0.068
2410004A20Rik	RIKEN cDNA 2410004A20 gene	0.068
Tenc1	tensin like C1 domain-containing phosphatase	0.068
Egr1	early growth response 1	0.068
Inha	inhibin alpha	0.068
Fam129b	family with sequence similarity 129, member B	0.067
Ms4a7	membrane-spanning 4-domains, subfamily A, member 7	0.067
Ms4a6c	membrane-spanning 4-domains, subfamily A, member 6C	0.067
Vcam1	vascular cell adhesion molecule 1	0.067
Clec5a	C-type lectin domain family 5, member a	0.067
Npy1r	neuropeptide Y receptor Y1	0.067
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.067
Tnfrsf11b	tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)	0.066
Epc1	enhancer of polycomb homolog 1 (Drosophila)	0.066
Phldb1	pleckstrin homology-like domain, family B, member 1	0.066
Nr2f6	nuclear receptor subfamily 2, group F, member 6	0.066
Gna13	guanine nucleotide binding protein, alpha 13	0.066
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.065
Pkp1	plakophilin 1	0.065
Cast	calpastatin	0.065
Rab3il1	RAB3A interacting protein (rabin3)-like 1	0.065
Ctnna1	catenin (cadherin associated protein), alpha 1	0.065
Cd68	CD68 antigen	0.064
Cxcl10	chemokine (C-X-C motif) ligand 10	0.064
Gfap	glial fibrillary acidic protein	0.064
Ms4a8a	membrane-spanning 4-domains, subfamily A, member 8A	0.064
Cd247	CD247 antigen	0.063
Cd209a	CD209a antigen	0.063	Mouse
5430435G22Rik	RIKEN cDNA 5430435G22 gene	0.063
Irf5	interferon regulatory factor 5	0.063
Arid1a	AT rich interactive domain 1A (SWI-like)	0.063
Tgfbi	transforming growth factor, beta induced	0.062
Bag3	BCL2-associated athanogene 3	0.062
Ptpn2	protein tyrosine phosphatase, non-receptor type 2	0.061
Cd27	CD27 antigen	0.061
Plcd1	phospholipase C, delta 1	0.060
Vwa5a	von Willebrand factor A domain containing 5A	0.060
Foxo3	forkhead box O3	0.060
Vpreb3	pre-B lymphocyte gene 3	0.060
Serpinb7	serine (or cysteine) peptidase inhibitor, clade B, member 7	0.060
Gm7609	predicted pseudogene 7609	0.060
Mecp2	methyl CpG binding protein 2	0.060
F9	coagulation factor IX	0.060
Eml3	echinoderm microtubule associated protein like 3	0.060
Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.060
Ghr	growth hormone receptor	0.059
Nat2	N-acetyltransferase 2 (arylamine N-acetyltransferase)	0.059
Mgl2	macrophage galactose N-acetyl-galactosamine specific lectin 2	0.059
Pnp	purine-nucleoside phosphorylase	0.059
Il12b	interleukin 12b	0.059
Mlkl	mixed lineage kinase domain-like	0.059
Ptger2	prostaglandin E receptor 2 (subtype EP2)	0.059
Samhd1	SAM domain and HD domain, 1	0.058
Kitl	kit ligand	0.058
Ptpn21	protein tyrosine phosphatase, non-receptor type 21	0.058
Fkbp7	FK506 binding protein 7	0.058
Ciita	class II transactivator	0.058	Mouse
Amotl2	angiomotin-like 2	0.057
Rhoh	ras homolog gene family, member H	0.057	Human
Igh	immunoglobulin heavy chain complex	0.057
Phldb2	pleckstrin homology-like domain, family B, member 2	0.057
Cd38	CD38 antigen	0.057
Rabep2	rabaptin, RAB GTPase binding effector protein 2	0.057
Il5ra	interleukin 5 receptor, alpha	0.057
Ido1	indoleamine 2,3-dioxygenase 1	0.057
Slurp1	secreted Ly6/Plaur domain containing 1	0.057
Ngp	neutrophilic granule protein	0.057
Il18	interleukin 18	0.056
Jag1	jagged 1	0.056
Foxp1	forkhead box P1	0.056
Pilrb1	paired immunoglobin-like type 2 receptor beta 1	0.056
Ticam2	toll-like receptor adaptor molecule 2	0.056	Zebrafish Mouse
Eif2c1	eukaryotic translation initiation factor 2C, 1	0.056
Tor3a	torsin family 3, member A	0.056
Ppp1r15a	protein phosphatase 1, regulatory (inhibitor) subunit 15A	0.056
Tspo	translocator protein	0.056
Hmgb1	high mobility group box 1	0.056
Kiss1r	KISS1 receptor	0.056
Mknk2	MAP kinase-interacting serine/threonine kinase 2	0.055
Prl	prolactin	0.055
Adam33	a disintegrin and metallopeptidase domain 33	0.055
Wac	WW domain containing adaptor with coiled-coil	0.055
Cxcl1	chemokine (C-X-C motif) ligand 1	0.055
Loxl2	lysyl oxidase-like 2	0.055
Axl	AXL receptor tyrosine kinase	0.055
Efs	embryonal Fyn-associated substrate	0.055
Tank	TRAF family member-associated Nf-kappa B activator	0.055
Klra5	killer cell lectin-like receptor, subfamily A, member 5	0.055
Gcet2	germinal center expressed transcript 2	0.055
Sgpl1	sphingosine phosphate lyase 1	0.055
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.054
Il2ra	interleukin 2 receptor, alpha chain	0.054
Hspb1	heat shock protein 1	0.054
Itga6	integrin alpha 6	0.054
Il33	interleukin 33	0.054
Gcm2	glial cells missing homolog 2 (Drosophila)	0.054
Nedd4	neural precursor cell expressed, developmentally down-regulated 4	0.054
Aoah	acyloxyacyl hydrolase	0.054
Gpr35	G protein-coupled receptor 35	0.053
Stat6	signal transducer and activator of transcription 6	0.053
Gzmb	granzyme B	0.053
Serpinb9	serine (or cysteine) peptidase inhibitor, clade B, member 9	0.053
Cdc42ep1	CDC42 effector protein (Rho GTPase binding) 1	0.053
Trafd1	TRAF type zinc finger domain containing 1	0.053
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.053
Egr2	early growth response 2	0.053
Tpst2	protein-tyrosine sulfotransferase 2	0.053
Eya2	eyes absent 2 homolog (Drosophila)	0.052
Prr12	proline rich 12	0.052
Il1a	interleukin 1 alpha	0.052	Mouse
Slfn1	schlafen 1	0.052
Grap2	GRB2-related adaptor protein 2	0.052
Cmah	cytidine monophospho-N-acetylneuraminic acid hydroxylase	0.052
Azi2	5-azacytidine induced gene 2	0.052
Ccl22	chemokine (C-C motif) ligand 22	0.052
Tnfaip2	tumor necrosis factor, alpha-induced protein 2	0.051
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.051
Irf9	interferon regulatory factor 9	0.051
Clec4a2	C-type lectin domain family 4, member a2	0.051	Mouse
Fasl	Fas ligand (TNF superfamily, member 6)	0.050	Human Mouse
Ctsb	cathepsin B	0.050
Zc3h12c	zinc finger CCCH type containing 12C	0.050
Ube2l6	ubiquitin-conjugating enzyme E2L 6	0.050
Keap1	kelch-like ECH-associated protein 1	0.050
Itgal	integrin alpha L	0.050
Fcgr4	Fc receptor, IgG, low affinity IV	0.050
Il20	interleukin 20	0.050
Maff	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)	0.050
Cd6	CD6 antigen	0.050
Pet2	plasmacytoma expressed transcript 2	0.050
Fcna	ficolin A	0.050
Klf3	Kruppel-like factor 3 (basic)	0.050
AI607873	expressed sequence AI607873	0.050
Stat4	signal transducer and activator of transcription 4	0.049
Gch1	GTP cyclohydrolase 1	0.049
Furin	furin (paired basic amino acid cleaving enzyme)	0.049
Cd209d	CD209d antigen	0.049	Mouse
Nfatc4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	0.049
Il34	interleukin 34	0.049
Cdcp1	CUB domain containing protein 1	0.049
Arhgef5	Rho guanine nucleotide exchange factor (GEF) 5	0.049
Spnb2	spectrin beta 2	0.049
Gem	GTP binding protein (gene overexpressed in skeletal muscle)	0.049
Ggta1	glycoprotein galactosyltransferase alpha 1, 3	0.048
Nr1h2	nuclear receptor subfamily 1, group H, member 2	0.048
Map3k1	mitogen-activated protein kinase kinase kinase 1	0.048
Mc5r	melanocortin 5 receptor	0.048
Samd9l	sterile alpha motif domain containing 9-like	0.048
Crlf3	cytokine receptor-like factor 3	0.048
Fos	FBJ osteosarcoma oncogene	0.048
Ftl1	ferritin light chain 1	0.048
H2-Ab1	histocompatibility 2, class II antigen A, beta 1	0.048
Trem1	triggering receptor expressed on myeloid cells 1	0.047
Vasn	vasorin	0.047
Col4a2	collagen, type IV, alpha 2	0.047
Ptpn23	protein tyrosine phosphatase, non-receptor type 23	0.047
Ccl12	chemokine (C-C motif) ligand 12	0.047
Rnf11	ring finger protein 11	0.047
Tab3	TGF-beta activated kinase 1/MAP3K7 binding protein 3	0.047
Larp4b	La ribonucleoprotein domain family, member 4B	0.047
Gbp2	guanylate binding protein 2	0.047
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.047
Ooep	oocyte expressed protein homolog (dog)	0.046
Zp1	zona pellucida glycoprotein 1	0.046
Csf1r	colony stimulating factor 1 receptor	0.046
Ciz1	CDKN1A interacting zinc finger protein 1	0.046
Fkbp10	FK506 binding protein 10	0.046
Map2k4	mitogen-activated protein kinase kinase 4	0.046
Tlr8	toll-like receptor 8	0.046	Human Mouse
Lbx1	ladybird homeobox homolog 1 (Drosophila)	0.046
Tnks1bp1	tankyrase 1 binding protein 1	0.046
Slc12a6	solute carrier family 12, member 6	0.046
Ifnb1	interferon beta 1, fibroblast	0.046
Klf9	Kruppel-like factor 9	0.046
Fth1	ferritin heavy chain 1	0.046
Akr1b8	aldo-keto reductase family 1, member B8	0.046
Aim1	absent in melanoma 1	0.045
Pld4	phospholipase D family, member 4	0.045
Retn	resistin	0.045
Mmp9	matrix metallopeptidase 9	0.045
Khdrbs1	KH domain containing, RNA binding, signal transduction associated 1	0.045
Tle1	transducin-like enhancer of split 1, homolog of Drosophila E(spl)	0.045	Human
Ptk2b	PTK2 protein tyrosine kinase 2 beta	0.045
Folr2	folate receptor 2 (fetal)	0.045
Sh3bp2	SH3-domain binding protein 2	0.045
Ets2	E26 avian leukemia oncogene 2, 3' domain	0.045
Apaf1	apoptotic peptidase activating factor 1	0.045
Pld2	phospholipase D2	0.045
Crhr2	corticotropin releasing hormone receptor 2	0.045
Ly6i	lymphocyte antigen 6 complex, locus I	0.045
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.045
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.045
Igsf6	immunoglobulin superfamily, member 6	0.044
Tor1aip2	torsin A interacting protein 2	0.044
Hbb-b1	hemoglobin, beta adult major chain	0.044
Tyrobp	TYRO protein tyrosine kinase binding protein	0.044
Tln1	talin 1	0.044
Tifa	TRAF-interacting protein with forkhead-associated domain	0.044
Fgfr4	fibroblast growth factor receptor 4	0.044
Hyal2	hyaluronoglucosaminidase 2	0.044
Rassf3	Ras association (RalGDS/AF-6) domain family member 3	0.044
Tnfrsf18	tumor necrosis factor receptor superfamily, member 18	0.044
Cks2	CDC28 protein kinase regulatory subunit 2	0.044
Impdh2	inosine 5'-phosphate dehydrogenase 2	0.044
Tnfrsf12a	tumor necrosis factor receptor superfamily, member 12a	0.044
Gsto1	glutathione S-transferase omega 1	0.044
Apc	adenomatosis polyposis coli	0.043
Casp7	caspase 7	0.043	Mouse
Has1	hyaluronan synthase1	0.043
Prf1	perforin 1 (pore forming protein)	0.043
Irf7	interferon regulatory factor 7	0.043
Fcgr3	Fc receptor, IgG, low affinity III	0.042
2010106G01Rik	RIKEN cDNA 2010106G01 gene	0.042
Plin2	perilipin 2	0.042
S1pr1	sphingosine-1-phosphate receptor 1	0.042
Vps54	vacuolar protein sorting 54 (yeast)	0.042
Runx1	runt related transcription factor 1	0.042
Ly75	lymphocyte antigen 75	0.042
H2-DMb2	histocompatibility 2, class II, locus Mb2	0.042
Fcer1a	Fc receptor, IgE, high affinity I, alpha polypeptide	0.042
Litaf	LPS-induced TN factor	0.042
Tnfsf9	tumor necrosis factor (ligand) superfamily, member 9	0.042
Tmod3	tropomodulin 3	0.042
Ccr2	chemokine (C-C motif) receptor 2	0.042
Psmb7	proteasome (prosome, macropain) subunit, beta type 7	0.042
Gnat1	guanine nucleotide binding protein, alpha transducing 1	0.041
Foxf1a	forkhead box F1a	0.041
Acpp	acid phosphatase, prostate	0.041
Expi	extracellular proteinase inhibitor	0.041
Cxcl5	chemokine (C-X-C motif) ligand 5	0.041
Shkbp1	Sh3kbp1 binding protein 1	0.041
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.041
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.041
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.041
Ncoa3	nuclear receptor coactivator 3	0.041
Cyp4f18	cytochrome P450, family 4, subfamily f, polypeptide 18	0.041
Mmp15	matrix metallopeptidase 15	0.041
Ripk2	receptor (TNFRSF)-interacting serine-threonine kinase 2	0.041
Pdlim3	PDZ and LIM domain 3	0.041
Ptpre	protein tyrosine phosphatase, receptor type, E	0.041
Mt1	metallothionein 1	0.041
Zap70	zeta-chain (TCR) associated protein kinase	0.040
Serpinb6b	serine (or cysteine) peptidase inhibitor, clade B, member 6b	0.040
Pgrmc1	progesterone receptor membrane component 1	0.040
Dll4	delta-like 4 (Drosophila)	0.040
Cd160	CD160 antigen	0.040
Cd80	CD80 antigen	0.040
Gpr97	G protein-coupled receptor 97	0.040
Lum	lumican	0.040
Rcn2	reticulocalbin 2	0.040
Sftpd	surfactant associated protein D	0.040
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.039
Lamc1	laminin, gamma 1	0.039
Ch25h	cholesterol 25-hydroxylase	0.039
Apobr	apolipoprotein B receptor	0.039
Was	Wiskott-Aldrich syndrome homolog (human)	0.039
Fbxw7	F-box and WD-40 domain protein 7	0.039
Il7r	interleukin 7 receptor	0.039
Pdcd1lg2	programmed cell death 1 ligand 2	0.039
Ninj1	ninjurin 1	0.039
Fshr	follicle stimulating hormone receptor	0.039
Cd209f	CD209f antigen	0.039
Clec4g	C-type lectin domain family 4, member g	0.038	Mouse
Ppm1a	protein phosphatase 1A, magnesium dependent, alpha isoform	0.038	Human
Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)	0.038
Cd7	CD7 antigen	0.038
Ptgr1	prostaglandin reductase 1	0.038
Zc3h11a	zinc finger CCCH type containing 11A	0.038
Vcl	vinculin	0.038
BC013712	cDNA sequence BC013712	0.038
Gzma	granzyme A	0.038
Pion	pigeon homolog (Drosophila)	0.038
Slc7a11	solute carrier family 7 (cationic amino acid transporter, y+ system), member 11	0.038
Tbc1d4	TBC1 domain family, member 4	0.038
Gabpb1	GA repeat binding protein, beta 1	0.038
Cpa3	carboxypeptidase A3, mast cell	0.038
Tuba1a	tubulin, alpha 1A	0.038
Fgf23	fibroblast growth factor 23	0.038
Klf13	Kruppel-like factor 13	0.038
Adcy2	adenylate cyclase 2	0.038
Arl6	ADP-ribosylation factor-like 6	0.038
Chi3l1	chitinase 3-like 1	0.038
Clcf1	cardiotrophin-like cytokine factor 1	0.038
Tmed10	transmembrane emp24-like trafficking protein 10 (yeast)	0.038
Sfrp4	secreted frizzled-related protein 4	0.038
Stk4	serine/threonine kinase 4	0.038
Gbp3	guanylate binding protein 3	0.038
Tubb6	tubulin, beta 6	0.038
Tradd	TNFRSF1A-associated via death domain	0.037	Human
Cblb	Casitas B-lineage lymphoma b	0.037
Rmnd5a	required for meiotic nuclear division 5 homolog A (S. cerevisiae)	0.037
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.037
Npepps	aminopeptidase puromycin sensitive	0.037
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.037
Egfl7	EGF-like domain 7	0.037
Ccng2	cyclin G2	0.037
Sin3a	transcriptional regulator, SIN3A (yeast)	0.037
Foxd3	forkhead box D3	0.037
Usp2	ubiquitin specific peptidase 2	0.037
Cnga1	cyclic nucleotide gated channel alpha 1	0.037
Per1	period homolog 1 (Drosophila)	0.037	Rat
Prdm1	PR domain containing 1, with ZNF domain	0.037
Nipbl	Nipped-B homolog (Drosophila)	0.036
Cxcr6	chemokine (C-X-C motif) receptor 6	0.036
Wsb1	WD repeat and SOCS box-containing 1	0.036
Ndel1	nuclear distribution gene E-like homolog 1 (A. nidulans)	0.036
Epha2	Eph receptor A2	0.036
Ppp4r1	protein phosphatase 4, regulatory subunit 1	0.036
Esr2	estrogen receptor 2 (beta)	0.036
Kcnj1	potassium inwardly-rectifying channel, subfamily J, member 1	0.036
Ttn	titin	0.036
Ankfy1	ankyrin repeat and FYVE domain containing 1	0.036
Irgm1	immunity-related GTPase family M member 1	0.036
S100a8	S100 calcium binding protein A8 (calgranulin A)	0.036
Fcer2a	Fc receptor, IgE, low affinity II, alpha polypeptide	0.036	Mouse
Tlr9	toll-like receptor 9	0.036	Mouse
Notch4	Notch gene homolog 4 (Drosophila)	0.036	Fly
Tlr7	toll-like receptor 7	0.036	Human Mouse
C230081A13Rik	RIKEN cDNA C230081A13 gene	0.036
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.036
Ppl	periplakin	0.036
C6	complement component 6	0.036
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.036
Ephb4	Eph receptor B4	0.036
Gbp1	guanylate binding protein 1	0.036
Scn5a	sodium channel, voltage-gated, type V, alpha	0.035
Sall1	sal-like 1 (Drosophila)	0.035
Abl2	v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)	0.035
Dok2	docking protein 2	0.035
Camsap1	calmodulin regulated spectrin-associated protein 1	0.035
Csda	cold shock domain protein A	0.035
Rgl2	ral guanine nucleotide dissociation stimulator-like 2	0.035
Trip10	thyroid hormone receptor interactor 10	0.035
Gimap3	GTPase, IMAP family member 3	0.035
Cflar	CASP8 and FADD-like apoptosis regulator	0.035	Human
Trim5	tripartite motif-containing 5	0.035	Human
Prkcdbp	protein kinase C, delta binding protein	0.035
Chd2	chromodomain helicase DNA binding protein 2	0.035
Gpr65	G-protein coupled receptor 65	0.035
Fam13b	family with sequence similarity 13, member B	0.035
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.035
Itpkb	inositol 1,4,5-trisphosphate 3-kinase B	0.035
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.035
Havcr2	hepatitis A virus cellular receptor 2	0.035
Dgkz	diacylglycerol kinase zeta	0.035
Bcl6	B-cell leukemia/lymphoma 6	0.035
Herc6	hect domain and RLD 6	0.035
Cebpd	CCAAT/enhancer binding protein (C/EBP), delta	0.035
Zcchc6	zinc finger, CCHC domain containing 6	0.035
Stap1	signal transducing adaptor family member 1	0.035
Optn	optineurin	0.035
Sh2d2a	SH2 domain protein 2A	0.034
Fyb	FYN binding protein	0.034
Iigp1	interferon inducible GTPase 1	0.034
Samd4	sterile alpha motif domain containing 4	0.034
Gdf9	growth differentiation factor 9	0.034
Csrnp1	cysteine-serine-rich nuclear protein 1	0.034
C77080	expressed sequence C77080	0.034
Vnn3	vanin 3	0.034
Tph1	tryptophan hydroxylase 1	0.034
Ccl6	chemokine (C-C motif) ligand 6	0.034
Pak2	p21 protein (Cdc42/Rac)-activated kinase 2	0.034
Parp9	poly (ADP-ribose) polymerase family, member 9	0.034
Xcl1	chemokine (C motif) ligand 1	0.034
March6	membrane-associated ring finger (C3HC4) 6	0.034
Slc12a4	solute carrier family 12, member 4	0.034
Il1rap	interleukin 1 receptor accessory protein	0.034	Mouse
Angpt1	angiopoietin 1	0.034
Tmbim1	transmembrane BAX inhibitor motif containing 1	0.034
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.034
Il1rl2	interleukin 1 receptor-like 2	0.034	Mouse
Gm11428	predicted gene 11428	0.034