IMP: Integrative Multi-species Prediction

Mus musculus

209 genes annotated in mouse

Multi-species View

negative regulation of immune system process

GO:0002683

Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouseInclude functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of immune system process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "negative regulation of immune system process" (in gray)

Name	Description	Probability	Func Analog Organism
Stat3	signal transducer and activator of transcription 3	1.000	Mouse
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.995
Lyz2	lysozyme 2	0.988
Hoxa10	homeobox A10	0.984	Mouse
Rb1	retinoblastoma 1	0.973
Myd88	myeloid differentiation primary response gene 88	0.972
Slamf1	signaling lymphocytic activation molecule family member 1	0.971
Traf6	TNF receptor-associated factor 6	0.963
Ccr1	chemokine (C-C motif) receptor 1	0.950
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.950
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.940
Pten	phosphatase and tensin homolog	0.935
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.934
Stat6	signal transducer and activator of transcription 6	0.931
Fyn	Fyn proto-oncogene	0.924	Mouse
Runx1	runt related transcription factor 1	0.898	Human
Hoxa9	homeobox A9	0.897
Hes1	hairy and enhancer of split 1 (Drosophila)	0.896	Human
Cyld	cylindromatosis (turban tumor syndrome)	0.893
Meox2	mesenchyme homeobox 2	0.890
Jak2	Janus kinase 2	0.884	Mouse
Nlrp3	NLR family, pyrin domain containing 3	0.879	Mouse
Irf1	interferon regulatory factor 1	0.877
Stat1	signal transducer and activator of transcription 1	0.871	Mouse
Hoxb5	homeobox B5	0.869	Mouse
Cd4	CD4 antigen	0.869
Il4ra	interleukin 4 receptor, alpha	0.866
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.866	Mouse
Ikzf1	IKAROS family zinc finger 1	0.855
Robo1	roundabout homolog 1 (Drosophila)	0.853
Inpp5d	inositol polyphosphate-5-phosphatase D	0.851
C3ar1	complement component 3a receptor 1	0.847
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.843
Il1r1	interleukin 1 receptor, type I	0.840	Mouse
Csf1r	colony stimulating factor 1 receptor	0.837	Mouse
Foxp3	forkhead box P3	0.835
Hoxc4	homeobox C4	0.835	Mouse
Ccr7	chemokine (C-C motif) receptor 7	0.833	Mouse
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.830	Mouse
Kit	kit oncogene	0.827	Mouse
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.824
Neurod1	neurogenic differentiation 1	0.818	Mouse
Itgal	integrin alpha L	0.818
Irf9	interferon regulatory factor 9	0.815	Mouse
Smad4	MAD homolog 4 (Drosophila)	0.813
Clec4d	C-type lectin domain family 4, member d	0.812	Mouse
Notch2	Notch gene homolog 2 (Drosophila)	0.809	Mouse
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.809
Socs3	suppressor of cytokine signaling 3	0.808	Mouse
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.807	Mouse
Cd40	CD40 antigen	0.800	Mouse
Hoxb9	homeobox B9	0.799	Mouse
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.795
Rara	retinoic acid receptor, alpha	0.794	Human
Fasl	Fas ligand (TNF superfamily, member 6)	0.794
Ptprc	protein tyrosine phosphatase, receptor type, C	0.789
Il10ra	interleukin 10 receptor, alpha	0.780
Itgax	integrin alpha X	0.777
AF251705	cDNA sequence AF251705	0.776	Mouse
Tnf	tumor necrosis factor	0.776
Itgb2	integrin beta 2	0.771
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.768
Axl	AXL receptor tyrosine kinase	0.766
Bcl2	B-cell leukemia/lymphoma 2	0.763
Ifng	interferon gamma	0.760
Sox2	SRY-box containing gene 2	0.759	Mouse
Il1b	interleukin 1 beta	0.751
Ccr2	chemokine (C-C motif) receptor 2	0.748
Trim21	tripartite motif-containing 21	0.744	Mouse
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.734
Casp8	caspase 8	0.724	Mouse
Sfrp2	secreted frizzled-related protein 2	0.723	Mouse
Cbl	Casitas B-lineage lymphoma	0.717	Mouse
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.714
Tlr4	toll-like receptor 4	0.711
Isl1	ISL1 transcription factor, LIM/homeodomain	0.703
Hoxa5	homeobox A5	0.703	Human Mouse
Hhex	hematopoietically expressed homeobox	0.699
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.699
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.696	Mouse
Nckap1l	NCK associated protein 1 like	0.696
Meox1	mesenchyme homeobox 1	0.695
Clec7a	C-type lectin domain family 7, member a	0.693
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.690
Icos	inducible T-cell co-stimulator	0.689
Grb2	growth factor receptor bound protein 2	0.689
Gata4	GATA binding protein 4	0.688	Mouse
Batf	basic leucine zipper transcription factor, ATF-like	0.684
Il2rb	interleukin 2 receptor, beta chain	0.681
Birc3	baculoviral IAP repeat-containing 3	0.675
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.672
Mapk14	mitogen-activated protein kinase 14	0.663	Fly
Cd19	CD19 antigen	0.662
Sox7	SRY-box containing gene 7	0.658	Mouse
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.656
Pax6	paired box gene 6	0.656
Sfpi1	SFFV proviral integration 1	0.655	Zebrafish
H2-Eb1	histocompatibility 2, class II antigen E beta	0.652
Ccl3	chemokine (C-C motif) ligand 3	0.646	Human
Tgfb1	transforming growth factor, beta 1	0.635
BC013712	cDNA sequence BC013712	0.635
Btg1	B-cell translocation gene 1, anti-proliferative	0.631
Lair1	leukocyte-associated Ig-like receptor 1	0.631
Cd86	CD86 antigen	0.628	Mouse
Smad6	MAD homolog 6 (Drosophila)	0.620
Gli2	GLI-Kruppel family member GLI2	0.619	Mouse
Pax3	paired box gene 3	0.616
Trem3	triggering receptor expressed on myeloid cells 3	0.613
Socs1	suppressor of cytokine signaling 1	0.613	Zebrafish Mouse
Sox4	SRY-box containing gene 4	0.612	Mouse
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.607
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.599
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.598
Cd28	CD28 antigen	0.594
Fcer2a	Fc receptor, IgE, low affinity II, alpha polypeptide	0.594	Mouse
Robo3	roundabout homolog 3 (Drosophila)	0.594
Ccl4	chemokine (C-C motif) ligand 4	0.592
Tgfb2	transforming growth factor, beta 2	0.591	Human Mouse Rat
Notch1	Notch gene homolog 1 (Drosophila)	0.590
Unc93b1	unc-93 homolog B1 (C. elegans)	0.587
Ltb	lymphotoxin B	0.583
Gzma	granzyme A	0.581
Tap1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.581	Rat
Mpeg1	macrophage expressed gene 1	0.581
Cd7	CD7 antigen	0.579
Hoxd10	homeobox D10	0.578	Mouse
Tmem176b	transmembrane protein 176B	0.577
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.573
Ubd	ubiquitin D	0.570
Zeb1	zinc finger E-box binding homeobox 1	0.568
Smad7	MAD homolog 7 (Drosophila)	0.568
Bmp4	bone morphogenetic protein 4	0.563	Human
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.563
Selp	selectin, platelet	0.558
Chd7	chromodomain helicase DNA binding protein 7	0.555
Cdh5	cadherin 5	0.553
Gdnf	glial cell line derived neurotrophic factor	0.553
Hoxc9	homeobox C9	0.551	Mouse
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.548
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.542
Tnip1	TNFAIP3 interacting protein 1	0.541
Alox5ap	arachidonate 5-lipoxygenase activating protein	0.538
Tapbp	TAP binding protein	0.538
Hoxc5	homeobox C5	0.536	Mouse
Hoxd9	homeobox D9	0.536	Mouse
Blk	B lymphoid kinase	0.535	Mouse
Bcl3	B-cell leukemia/lymphoma 3	0.533	Mouse
Fzd4	frizzled homolog 4 (Drosophila)	0.529
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.522
Fos	FBJ osteosarcoma oncogene	0.521
Tmem176a	transmembrane protein 176A	0.519
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.519
Ccl2	chemokine (C-C motif) ligand 2	0.518
C1qa	complement component 1, q subcomponent, alpha polypeptide	0.514
Irf8	interferon regulatory factor 8	0.513	Mouse
Fgfr2	fibroblast growth factor receptor 2	0.512
H2-DMb2	histocompatibility 2, class II, locus Mb2	0.511
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.508
Ciita	class II transactivator	0.507
Tyrobp	TYRO protein tyrosine kinase binding protein	0.506
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.506
Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.505	Rat
Cd14	CD14 antigen	0.502
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.496	Human
Sell	selectin, lymphocyte	0.496
Siglece	sialic acid binding Ig-like lectin E	0.492
Ccl5	chemokine (C-C motif) ligand 5	0.489
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.489	Mouse
Abp1	amiloride binding protein 1 (amine oxidase, copper-containing)	0.488
Gnrh1	gonadotropin releasing hormone 1	0.487
Ebi3	Epstein-Barr virus induced gene 3	0.484
Ncf4	neutrophil cytosolic factor 4	0.481
Ly9	lymphocyte antigen 9	0.477
Cd84	CD84 antigen	0.476
Cytip	cytohesin 1 interacting protein	0.473
Muc13	mucin 13, epithelial transmembrane	0.473
Traf3ip2	TRAF3 interacting protein 2	0.471
C1qb	complement component 1, q subcomponent, beta polypeptide	0.471
Myo1f	myosin IF	0.468
Trim30a	tripartite motif-containing 30A	0.466
Atf2	activating transcription factor 2	0.463
Irak3	interleukin-1 receptor-associated kinase 3	0.462
Pbx1	pre B-cell leukemia transcription factor 1	0.460
Ccl8	chemokine (C-C motif) ligand 8	0.460
Mefv	Mediterranean fever	0.460
Fgf10	fibroblast growth factor 10	0.460
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.454	Mouse
Mst1r	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)	0.454	Mouse
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.454
Ddx60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.452
Hoxd11	homeobox D11	0.452
Shh	sonic hedgehog	0.449
Has2	hyaluronan synthase 2	0.447
Gata1	GATA binding protein 1	0.443	Mouse
Hcst	hematopoietic cell signal transducer	0.442
Dock2	dedicator of cyto-kinesis 2	0.439
Mmp12	matrix metallopeptidase 12	0.438	Mouse
Lhx3	LIM homeobox protein 3	0.436
Snai1	snail homolog 1 (Drosophila)	0.433
Ptf1a	pancreas specific transcription factor, 1a	0.432	Mouse
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.431	Mouse
Gzmb	granzyme B	0.429
Cxcl13	chemokine (C-X-C motif) ligand 13	0.424
Xcl1	chemokine (C motif) ligand 1	0.423
Il1rl1	interleukin 1 receptor-like 1	0.423
Hoxc6	homeobox C6	0.421	Mouse
Cd209a	CD209a antigen	0.420	Mouse
Smad3	MAD homolog 3 (Drosophila)	0.419
Ly86	lymphocyte antigen 86	0.417
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.416
Klra17	killer cell lectin-like receptor, subfamily A, member 17	0.415
F13a1	coagulation factor XIII, A1 subunit	0.412
Il18r1	interleukin 18 receptor 1	0.412	Mouse
Stat2	signal transducer and activator of transcription 2	0.411	Mouse
Oas3	2'-5' oligoadenylate synthetase 3	0.411
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.407
H2-K1	histocompatibility 2, K1, K region	0.405	Rat
Cst7	cystatin F (leukocystatin)	0.402
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.401	Mouse
Aoah	acyloxyacyl hydrolase	0.399
Emx1	empty spiracles homolog 1 (Drosophila)	0.398
Fas	Fas (TNF receptor superfamily member 6)	0.396
Cd180	CD180 antigen	0.395
Gli3	GLI-Kruppel family member GLI3	0.392
Lhx6	LIM homeobox protein 6	0.391
Il6st	interleukin 6 signal transducer	0.388	Mouse
Tbx2	T-box 2	0.388
Txk	TXK tyrosine kinase	0.387	Mouse
Irgm1	immunity-related GTPase family M member 1	0.386
Rc3h1	RING CCCH (C3H) domains 1	0.386
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.385
Tlr7	toll-like receptor 7	0.385
Casp1	caspase 1	0.383	Mouse
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.382
Fes	feline sarcoma oncogene	0.381	Mouse
Gas1	growth arrest specific 1	0.381
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.381
Cxcr3	chemokine (C-X-C motif) receptor 3	0.380	Mouse
Tal1	T-cell acute lymphocytic leukemia 1	0.379	Mouse
Ctnnb1	catenin (cadherin associated protein), beta 1	0.378
Pilrb1	paired immunoglobin-like type 2 receptor beta 1	0.374
Cmklr1	chemokine-like receptor 1	0.372
Guca2a	guanylate cyclase activator 2a (guanylin)	0.371
Gbp7	guanylate binding protein 7	0.370
Blnk	B-cell linker	0.367
Hoxb8	homeobox B8	0.363
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.362
Gata6	GATA binding protein 6	0.361	Mouse
Tgfbr1	transforming growth factor, beta receptor I	0.361
Cd96	CD96 antigen	0.360
Zfp703	zinc finger protein 703	0.360
Hoxc8	homeobox C8	0.359	Mouse
Prkcd	protein kinase C, delta	0.359
Hoxb2	homeobox B2	0.358
Inhba	inhibin beta-A	0.356
Lcp1	lymphocyte cytosolic protein 1	0.352
Sfrp1	secreted frizzled-related protein 1	0.351
Cd244	CD244 natural killer cell receptor 2B4	0.351
Il10	interleukin 10	0.348
Zap70	zeta-chain (TCR) associated protein kinase	0.348
Efs	embryonal Fyn-associated substrate	0.347
Mdm4	transformed mouse 3T3 cell double minute 4	0.347
Ms4a6d	membrane-spanning 4-domains, subfamily A, member 6D	0.346
Slc25a48	solute carrier family 25, member 48	0.345
Tcf21	transcription factor 21	0.345
Ntf3	neurotrophin 3	0.343
Kdr	kinase insert domain protein receptor	0.337	Mouse
Cd33	CD33 antigen	0.337
Gpr65	G-protein coupled receptor 65	0.337	Mouse
C3	complement component 3	0.336
Dll1	delta-like 1 (Drosophila)	0.335
Slamf7	SLAM family member 7	0.334
Plac8	placenta-specific 8	0.333
Clec4e	C-type lectin domain family 4, member e	0.332	Mouse
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.332
Dpep3	dipeptidase 3	0.331
Ido1	indoleamine 2,3-dioxygenase 1	0.331
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.331
Gpr33	G protein-coupled receptor 33	0.329
Rxra	retinoid X receptor alpha	0.328
Sp100	nuclear antigen Sp100	0.328
Gpr132	G protein-coupled receptor 132	0.328	Mouse
Prrx1	paired related homeobox 1	0.325
Cd6	CD6 antigen	0.324
Ccr6	chemokine (C-C motif) receptor 6	0.324	Mouse
Adcy4	adenylate cyclase 4	0.324
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.323	Mouse
Tbx21	T-box 21	0.323
Mc2r	melanocortin 2 receptor	0.323
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.322
Epsti1	epithelial stromal interaction 1 (breast)	0.321
Ar	androgen receptor	0.320
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.319
Il18rap	interleukin 18 receptor accessory protein	0.318	Mouse
Retnlb	resistin like beta	0.318
Runx1t1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.317
Selplg	selectin, platelet (p-selectin) ligand	0.316
H2-DMa	histocompatibility 2, class II, locus DMa	0.316
Nf1	neurofibromatosis 1	0.315
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.313
Gab1	growth factor receptor bound protein 2-associated protein 1	0.312
Rab3il1	RAB3A interacting protein (rabin3)-like 1	0.311
Clec4a2	C-type lectin domain family 4, member a2	0.311	Mouse
Trim30d	tripartite motif-containing 30D	0.311	Mouse
Laptm5	lysosomal-associated protein transmembrane 5	0.310
Trp53	transformation related protein 53	0.309
Cdkn2b	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	0.308	Mouse
Il1rn	interleukin 1 receptor antagonist	0.308
Pdgfb	platelet derived growth factor, B polypeptide	0.308
Htra3	HtrA serine peptidase 3	0.307
Il7r	interleukin 7 receptor	0.306
Cd274	CD274 antigen	0.305
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.305
Ctsw	cathepsin W	0.302
Hoxd4	homeobox D4	0.301	Mouse
Ifngr1	interferon gamma receptor 1	0.301
Was	Wiskott-Aldrich syndrome homolog (human)	0.299
Acvrl1	activin A receptor, type II-like 1	0.299	Fly
Clec4n	C-type lectin domain family 4, member n	0.298	Mouse
Itga3	integrin alpha 3	0.298
Pik3ap1	phosphoinositide-3-kinase adaptor protein 1	0.296
Neurog3	neurogenin 3	0.296	Mouse
Igsf6	immunoglobulin superfamily, member 6	0.295
Aif1	allograft inflammatory factor 1	0.295
Cd22	CD22 antigen	0.295
Lmo1	LIM domain only 1	0.294	Mouse
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.294
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.293	Mouse
Klra5	killer cell lectin-like receptor, subfamily A, member 5	0.293
Ier2	immediate early response 2	0.292
Psen1	presenilin 1	0.292
Ncf2	neutrophil cytosolic factor 2	0.291
Sh2d2a	SH2 domain protein 2A	0.290
Gata2	GATA binding protein 2	0.290
Cd3d	CD3 antigen, delta polypeptide	0.289
Ccl9	chemokine (C-C motif) ligand 9	0.289
Nkg7	natural killer cell group 7 sequence	0.289
Meis2	Meis homeobox 2	0.288
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.288
Spib	Spi-B transcription factor (Spi-1/PU.1 related)	0.286
Sox18	SRY-box containing gene 18	0.286	Mouse
Glycam1	glycosylation dependent cell adhesion molecule 1	0.286
Pds5b	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.285
Vegfa	vascular endothelial growth factor A	0.284
Dab1	disabled homolog 1 (Drosophila)	0.284
Pim1	proviral integration site 1	0.283
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.283
H2-Q6	histocompatibility 2, Q region locus 6	0.283	Rat
Egfr	epidermal growth factor receptor	0.283	Mouse
Cxcr2	chemokine (C-X-C motif) receptor 2	0.282	Mouse Rat
Ephb2	Eph receptor B2	0.278
Twist2	twist homolog 2 (Drosophila)	0.276
Plcg1	phospholipase C, gamma 1	0.275	Mouse
Expi	extracellular proteinase inhibitor	0.275
Hck	hemopoietic cell kinase	0.275	Mouse
Pdcd1	programmed cell death 1	0.274
Creb3l1	cAMP responsive element binding protein 3-like 1	0.272
Pdcd1lg2	programmed cell death 1 ligand 2	0.271
Elk4	ELK4, member of ETS oncogene family	0.271
Fzd1	frizzled homolog 1 (Drosophila)	0.271
AW112010	expressed sequence AW112010	0.269
Neurod4	neurogenic differentiation 4	0.269	Mouse
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.269
Prss30	protease, serine, 30	0.269
Cd300ld	CD300 molecule-like family member d	0.266	Mouse
Lcn4	lipocalin 4	0.266
Sufu	suppressor of fused homolog (Drosophila)	0.265
Zfp503	zinc finger protein 503	0.265
Slc15a3	solute carrier family 15, member 3	0.264
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.262
Inhbb	inhibin beta-B	0.261
Aplnr	apelin receptor	0.261
Hoxc10	homeobox C10	0.261	Mouse
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.260
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.259
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.259
Phox2b	paired-like homeobox 2b	0.257
Lyl1	lymphoblastomic leukemia 1	0.257	Mouse
Nfam1	Nfat activating molecule with ITAM motif 1	0.257
Irf4	interferon regulatory factor 4	0.256
Des	desmin	0.254
Saa4	serum amyloid A 4	0.253
She	src homology 2 domain-containing transforming protein E	0.253
Ms4a7	membrane-spanning 4-domains, subfamily A, member 7	0.253
Ncr1	natural cytotoxicity triggering receptor 1	0.252
Zfp36	zinc finger protein 36	0.251
Lcp2	lymphocyte cytosolic protein 2	0.251
H2-Aa	histocompatibility 2, class II antigen A, alpha	0.250	Rat
Ccl6	chemokine (C-C motif) ligand 6	0.250
Ptges	prostaglandin E synthase	0.249
Msr1	macrophage scavenger receptor 1	0.247
Cxcl9	chemokine (C-X-C motif) ligand 9	0.247
Pou2af1	POU domain, class 2, associating factor 1	0.246
Tlr2	toll-like receptor 2	0.246
Ncoa3	nuclear receptor coactivator 3	0.245
Adam17	a disintegrin and metallopeptidase domain 17	0.245
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.243
Ms4a4b	membrane-spanning 4-domains, subfamily A, member 4B	0.242
Gdf9	growth differentiation factor 9	0.242
Dnm1	dynamin 1	0.241
Ubc	ubiquitin C	0.241
Gm10229	predicted gene 10229	0.240
Ptpn2	protein tyrosine phosphatase, non-receptor type 2	0.240
Sash3	SAM and SH3 domain containing 3	0.240	Mouse
Pyhin1	pyrin and HIN domain family, member 1	0.240
Emr4	EGF-like module containing, mucin-like, hormone receptor-like sequence 4	0.240
Mrc1	mannose receptor, C type 1	0.239
Igf1	insulin-like growth factor 1	0.238
Cd3e	CD3 antigen, epsilon polypeptide	0.237
Ddr2	discoidin domain receptor family, member 2	0.237
Fxyd2	FXYD domain-containing ion transport regulator 2	0.237
Niacr1	niacin receptor 1	0.237
Clec4b1	C-type lectin domain family 4, member b1	0.235	Mouse
Gbp1	guanylate binding protein 1	0.235
Errfi1	ERBB receptor feedback inhibitor 1	0.235
Il6	interleukin 6	0.234
Smo	smoothened homolog (Drosophila)	0.234
Lyz1	lysozyme 1	0.233	Fly
Ccnd1	cyclin D1	0.233
Flt3	FMS-like tyrosine kinase 3	0.233
Skil	SKI-like	0.232
Acpp	acid phosphatase, prostate	0.232
Fcgr1	Fc receptor, IgG, high affinity I	0.232	Mouse
Tcra	T-cell receptor alpha chain	0.232
Wnt5a	wingless-related MMTV integration site 5A	0.230
Apobec1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	0.229
Tifa	TRAF-interacting protein with forkhead-associated domain	0.228
Pbx3	pre B-cell leukemia transcription factor 3	0.228
Tert	telomerase reverse transcriptase	0.228
Sox10	SRY-box containing gene 10	0.227	Mouse
Traf1	TNF receptor-associated factor 1	0.227
Arhgap4	Rho GTPase activating protein 4	0.227
Ccl24	chemokine (C-C motif) ligand 24	0.226
Uba7	ubiquitin-like modifier activating enzyme 7	0.226
Mrc2	mannose receptor, C type 2	0.226
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.226
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.226
Fndc7	fibronectin type III domain containing 7	0.225
Reg3g	regenerating islet-derived 3 gamma	0.225
Pilra	paired immunoglobin-like type 2 receptor alpha	0.225
Eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2	0.224
Tnfsf8	tumor necrosis factor (ligand) superfamily, member 8	0.224
Ltbp2	latent transforming growth factor beta binding protein 2	0.223
Abcg3	ATP-binding cassette, sub-family G (WHITE), member 3	0.223
Cxcl12	chemokine (C-X-C motif) ligand 12	0.223	Human Zebrafish
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.222
Adam8	a disintegrin and metallopeptidase domain 8	0.222
Dok1	docking protein 1	0.222
Arap3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.221
Neurog2	neurogenin 2	0.220	Mouse
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.219
Tlr8	toll-like receptor 8	0.219
Ptgir	prostaglandin I receptor (IP)	0.218
Ccl22	chemokine (C-C motif) ligand 22	0.218
Clec10a	C-type lectin domain family 10, member A	0.217
Cr2	complement receptor 2	0.217
Cd59a	CD59a antigen	0.217
Prrx2	paired related homeobox 2	0.216
Ifnar1	interferon (alpha and beta) receptor 1	0.216	Mouse
Btg2	B-cell translocation gene 2, anti-proliferative	0.216
Irak4	interleukin-1 receptor-associated kinase 4	0.216
Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.215
Cybb	cytochrome b-245, beta polypeptide	0.215
Pld4	phospholipase D family, member 4	0.214
Fzd8	frizzled homolog 8 (Drosophila)	0.213
H2-D1	histocompatibility 2, D region locus 1	0.213
Slfn4	schlafen 4	0.213
Gimap7	GTPase, IMAP family member 7	0.213
Ccnd2	cyclin D2	0.213
Cd48	CD48 antigen	0.212
Eya4	eyes absent 4 homolog (Drosophila)	0.211
Rhoh	ras homolog gene family, member H	0.211
Sla2	Src-like-adaptor 2	0.209
Nrarp	Notch-regulated ankyrin repeat protein	0.209
Irg1	immunoresponsive gene 1	0.208
Gpr35	G protein-coupled receptor 35	0.208
Apc	adenomatosis polyposis coli	0.207
Mmp8	matrix metallopeptidase 8	0.206	Mouse
Nkx3-1	NK-3 transcription factor, locus 1 (Drosophila)	0.206
Hoxb4	homeobox B4	0.205	Mouse
F2r	coagulation factor II (thrombin) receptor	0.204	Zebrafish
Pstpip2	proline-serine-threonine phosphatase-interacting protein 2	0.203
Pitx1	paired-like homeodomain transcription factor 1	0.203
Chl1	cell adhesion molecule with homology to L1CAM	0.201
Klra9	killer cell lectin-like receptor subfamily A, member 9	0.201
Fyb	FYN binding protein	0.201
Prf1	perforin 1 (pore forming protein)	0.200
Gmnn	geminin	0.200
Batf2	basic leucine zipper transcription factor, ATF-like 2	0.199
Ifi203	interferon activated gene 203	0.198
Ikbkg	inhibitor of kappaB kinase gamma	0.198
Gm12185	predicted gene 12185	0.198
Fgf5	fibroblast growth factor 5	0.196
Ikbkb	inhibitor of kappaB kinase beta	0.195
Flt1	FMS-like tyrosine kinase 1	0.195	Mouse
Il17a	interleukin 17A	0.195
Dnase1l3	deoxyribonuclease 1-like 3	0.195
Nos3	nitric oxide synthase 3, endothelial cell	0.195
Cd300a	CD300A antigen	0.194
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.193
Chi3l1	chitinase 3-like 1	0.193
Ldb2	LIM domain binding 2	0.193	Mouse
Tal2	T-cell acute lymphocytic leukemia 2	0.192	Mouse
Mmp9	matrix metallopeptidase 9	0.192	Mouse
Trim25	tripartite motif-containing 25	0.191
Pitx2	paired-like homeodomain transcription factor 2	0.191
B4galnt2	beta-1,4-N-acetyl-galactosaminyl transferase 2	0.191
Sorbs3	sorbin and SH3 domain containing 3	0.190
Foxf1a	forkhead box F1a	0.189
Ccr5	chemokine (C-C motif) receptor 5	0.189	Mouse
Glis3	GLIS family zinc finger 3	0.189	Mouse
Chst2	carbohydrate sulfotransferase 2	0.189
Prl	prolactin	0.189
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.188
Ncf1	neutrophil cytosolic factor 1	0.188
H2-Q7	histocompatibility 2, Q region locus 7	0.188
Hic1	hypermethylated in cancer 1	0.188
Mx1	myxovirus (influenza virus) resistance 1	0.188
Lbp	lipopolysaccharide binding protein	0.188
Shc1	src homology 2 domain-containing transforming protein C1	0.187
Ltc4s	leukotriene C4 synthase	0.187
Cldn5	claudin 5	0.187
Gpr18	G protein-coupled receptor 18	0.187
Gm9880	predicted gene 9880	0.187
Cd37	CD37 antigen	0.187
B2m	beta-2 microglobulin	0.187
Robo2	roundabout homolog 2 (Drosophila)	0.186
Il21r	interleukin 21 receptor	0.185
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.185
Apaf1	apoptotic peptidase activating factor 1	0.184	Fly
Parp14	poly (ADP-ribose) polymerase family, member 14	0.184
Olig2	oligodendrocyte transcription factor 2	0.184
Pnmt	phenylethanolamine-N-methyltransferase	0.184
Pycard	PYD and CARD domain containing	0.183
H2-Oa	histocompatibility 2, O region alpha locus	0.182	Human
Fhl3	four and a half LIM domains 3	0.182	Mouse
Tyro3	TYRO3 protein tyrosine kinase 3	0.181
Oit1	oncoprotein induced transcript 1	0.181
Lmo2	LIM domain only 2	0.180
P2ry6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.180
Pik3cb	phosphatidylinositol 3-kinase, catalytic, beta polypeptide	0.179
Pax5	paired box gene 5	0.178
Cd3g	CD3 antigen, gamma polypeptide	0.178
Cd5	CD5 antigen	0.177
Cd300lb	CD300 antigen like family member B	0.177	Mouse
H2-Ob	histocompatibility 2, O region beta locus	0.177
Tgfbr3	transforming growth factor, beta receptor III	0.176
Naip5	NLR family, apoptosis inhibitory protein 5	0.175
Slit2	slit homolog 2 (Drosophila)	0.175	Human Mouse Rat
Tnfsf10	tumor necrosis factor (ligand) superfamily, member 10	0.175
Foxd2	forkhead box D2	0.175
Cd160	CD160 antigen	0.175
Plek	pleckstrin	0.175
Per1	period homolog 1 (Drosophila)	0.174
Ms4a6b	membrane-spanning 4-domains, subfamily A, member 6B	0.173
Lrg1	leucine-rich alpha-2-glycoprotein 1	0.173
Cd209c	CD209c antigen	0.173	Mouse
C4b	complement component 4B (Childo blood group)	0.173
Acvr2b	activin receptor IIB	0.172
LOC677008	natural killer cell receptor 2B4-like	0.172
Nkx3-2	NK3 homeobox 2	0.172
Tlr6	toll-like receptor 6	0.171
Tgfbr2	transforming growth factor, beta receptor II	0.171
Stap1	signal transducing adaptor family member 1	0.171
Il2ra	interleukin 2 receptor, alpha chain	0.171
Wac	WW domain containing adaptor with coiled-coil	0.170
Akp3	alkaline phosphatase 3, intestine, not Mn requiring	0.170
Adamdec1	ADAM-like, decysin 1	0.169
Siglecg	sialic acid binding Ig-like lectin G	0.169
Mpo	myeloperoxidase	0.169
Irf7	interferon regulatory factor 7	0.169	Mouse
Parp9	poly (ADP-ribose) polymerase family, member 9	0.169
Fut7	fucosyltransferase 7	0.169
Cysltr1	cysteinyl leukotriene receptor 1	0.169
Btbd17	BTB (POZ) domain containing 17	0.168
Pla2r1	phospholipase A2 receptor 1	0.168
Foxc2	forkhead box C2	0.168
Itgae	integrin alpha E, epithelial-associated	0.167
Tnfaip8l2	tumor necrosis factor, alpha-induced protein 8-like 2	0.167
Runx3	runt related transcription factor 3	0.166
Tcf7	transcription factor 7, T-cell specific	0.166
Pstpip1	proline-serine-threonine phosphatase-interacting protein 1	0.165
Fcgr4	Fc receptor, IgG, low affinity IV	0.165
Gja4	gap junction protein, alpha 4	0.164
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.164
Klrb1a	killer cell lectin-like receptor subfamily B member 1A	0.164	Mouse
Mycl1	v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)	0.163
Rhog	ras homolog gene family, member G	0.163
Shank3	SH3/ankyrin domain gene 3	0.163
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.162
Prkch	protein kinase C, eta	0.162
Lgals2	lectin, galactose-binding, soluble 2	0.161
Xcr1	chemokine (C motif) receptor 1	0.161	Mouse
Aicda	activation-induced cytidine deaminase	0.161
Hoxb3	homeobox B3	0.161
Alx4	aristaless-like homeobox 4	0.161
S1pr4	sphingosine-1-phosphate receptor 4	0.160
Pvrl2	poliovirus receptor-related 2	0.160
Aim2	absent in melanoma 2	0.160
Fpr-rs4	formyl peptide receptor, related sequence 4	0.160
Hgf	hepatocyte growth factor	0.160
Epb4.2	erythrocyte protein band 4.2	0.159
Cd74	CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)	0.159
Psen2	presenilin 2	0.159
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.159
Egfl7	EGF-like domain 7	0.158
Fpr3	formyl peptide receptor 3	0.158
P2rx1	purinergic receptor P2X, ligand-gated ion channel, 1	0.158
Mab21l2	mab-21-like 2 (C. elegans)	0.157
Htr7	5-hydroxytryptamine (serotonin) receptor 7	0.157
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.157
Zfp830	zinc finger protein 830	0.157
Slit3	slit homolog 3 (Drosophila)	0.157	Mouse
Ccl17	chemokine (C-C motif) ligand 17	0.157
Ctsh	cathepsin H	0.157
Cnr2	cannabinoid receptor 2 (macrophage)	0.156	Rat
C5ar1	complement component 5a receptor 1	0.156
Kcnk3	potassium channel, subfamily K, member 3	0.156
Cbfa2t3	core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)	0.156
Myb	myeloblastosis oncogene	0.156
Vmn2r26	vomeronasal 2, receptor 26	0.156
Esr1	estrogen receptor 1 (alpha)	0.155
Trem1	triggering receptor expressed on myeloid cells 1	0.155
Tiparp	TCDD-inducible poly(ADP-ribose) polymerase	0.154
Cd52	CD52 antigen	0.154
Spef1	sperm flagellar 1	0.154
Ssbp3	single-stranded DNA binding protein 3	0.154
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.154
Tgfbi	transforming growth factor, beta induced	0.153
Ly6i	lymphocyte antigen 6 complex, locus I	0.153
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.153
E2f1	E2F transcription factor 1	0.153
Acvr1b	activin A receptor, type 1B	0.153
Hmox1	heme oxygenase (decycling) 1	0.152
Sp110	Sp110 nuclear body protein	0.152
Trafd1	TRAF type zinc finger domain containing 1	0.152
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2	0.152
Tff3	trefoil factor 3, intestinal	0.152	Mouse
Tnks1bp1	tankyrase 1 binding protein 1	0.152
Nod2	nucleotide-binding oligomerization domain containing 2	0.151
Tbxas1	thromboxane A synthase 1, platelet	0.151
Cd72	CD72 antigen	0.151
AI607873	expressed sequence AI607873	0.151
Gpr50	G-protein-coupled receptor 50	0.150
Usp18	ubiquitin specific peptidase 18	0.150
Ifitm6	interferon induced transmembrane protein 6	0.150
Bnc1	basonuclin 1	0.150
Dll4	delta-like 4 (Drosophila)	0.150	Mouse
Fcer1a	Fc receptor, IgE, high affinity I, alpha polypeptide	0.150	Mouse
Zc3h12a	zinc finger CCCH type containing 12A	0.150
Rel	reticuloendotheliosis oncogene	0.149
Kitl	kit ligand	0.149
Amh	anti-Mullerian hormone	0.149
Cd8a	CD8 antigen, alpha chain	0.149
Mapk11	mitogen-activated protein kinase 11	0.148	Fly
Psmb8	proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)	0.148
Gzmk	granzyme K	0.148
Ptpro	protein tyrosine phosphatase, receptor type, O	0.147	Mouse
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.147
Ccr1l1	chemokine (C-C motif) receptor 1-like 1	0.147	Mouse
Trim12a	tripartite motif-containing 12A	0.147	Mouse
Ren1	renin 1 structural	0.147
S1pr1	sphingosine-1-phosphate receptor 1	0.146
Ets1	E26 avian leukemia oncogene 1, 5' domain	0.146
Rhoj	ras homolog gene family, member J	0.146
Cdh23	cadherin 23 (otocadherin)	0.145
Gabpb1	GA repeat binding protein, beta 1	0.145
Cachd1	cache domain containing 1	0.145
Egr2	early growth response 2	0.145
Wnt6	wingless-related MMTV integration site 6	0.145
Clec5a	C-type lectin domain family 5, member a	0.145	Mouse
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.144
Lat2	linker for activation of T cells family, member 2	0.144
Mdm2	transformed mouse 3T3 cell double minute 2	0.144
Dkc1	dyskeratosis congenita 1, dyskerin homolog (human)	0.144
Tnfrsf18	tumor necrosis factor receptor superfamily, member 18	0.144
Grap2	GRB2-related adaptor protein 2	0.144
F2rl3	coagulation factor II (thrombin) receptor-like 3	0.143
Pax8	paired box gene 8	0.143
Meis1	Meis homeobox 1	0.143
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.142
Ssbp2	single-stranded DNA binding protein 2	0.142
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.142
Tll1	tolloid-like	0.142
Zp1	zona pellucida glycoprotein 1	0.142
Itga2	integrin alpha 2	0.142
Hoxa1	homeobox A1	0.141
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.141
Mmp11	matrix metallopeptidase 11	0.141	Mouse
Itgb5	integrin beta 5	0.141
Notch3	Notch gene homolog 3 (Drosophila)	0.140	Mouse
Apbb1ip	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	0.139
2010106G01Rik	RIKEN cDNA 2010106G01 gene	0.139
Csf2ra	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	0.139
Dmpk	dystrophia myotonica-protein kinase	0.139
Elf4	E74-like factor 4 (ets domain transcription factor)	0.139	Mouse
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.138
H2-M9	histocompatibility 2, M region locus 9	0.138
Zfp36l2	zinc finger protein 36, C3H type-like 2	0.138	Mouse
Mapk8	mitogen-activated protein kinase 8	0.138
Plcb3	phospholipase C, beta 3	0.137	Mouse
Rasal3	RAS protein activator like 3	0.137
Parp12	poly (ADP-ribose) polymerase family, member 12	0.137
Mpp5	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)	0.137
Slamf8	SLAM family member 8	0.137
Cfc1	cripto, FRL-1, cryptic family 1	0.137
Sprr2k	small proline-rich protein 2K	0.136
Bach2	BTB and CNC homology 2	0.136
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.136
Clec2i	C-type lectin domain family 2, member i	0.136	Mouse
Slpi	secretory leukocyte peptidase inhibitor	0.136
Gcm1	glial cells missing homolog 1 (Drosophila)	0.136	Fly
Rasa1	RAS p21 protein activator 1	0.136
Cdk4	cyclin-dependent kinase 4	0.136
Star	steroidogenic acute regulatory protein	0.135
Spna1	spectrin alpha 1	0.135
Mcpt1	mast cell protease 1	0.135
Stx11	syntaxin 11	0.135
App	amyloid beta (A4) precursor protein	0.135
Casp3	caspase 3	0.135
Evi2b	ecotropic viral integration site 2b	0.135
Sykb	spleen tyrosine kinase	0.134
Anpep	alanyl (membrane) aminopeptidase	0.134
Cd8b1	CD8 antigen, beta chain 1	0.133
Epas1	endothelial PAS domain protein 1	0.133
Il33	interleukin 33	0.133
Naa30	N(alpha)-acetyltransferase 30, NatC catalytic subunit	0.133
Spsb2	splA/ryanodine receptor domain and SOCS box containing 2	0.133
Foxf2	forkhead box F2	0.132	Mouse
F9	coagulation factor IX	0.132
Cxcl5	chemokine (C-X-C motif) ligand 5	0.132
Slamf6	SLAM family member 6	0.132
Mmp10	matrix metallopeptidase 10	0.132	Mouse
Edn3	endothelin 3	0.132
Amhr2	anti-Mullerian hormone type 2 receptor	0.132
Gcet2	germinal center expressed transcript 2	0.132
Gpsm3	G-protein signalling modulator 3 (AGS3-like, C. elegans)	0.132
Fcgr3	Fc receptor, IgG, low affinity III	0.132	Mouse
Mvp	major vault protein	0.132
P2ry13	purinergic receptor P2Y, G-protein coupled 13	0.132
Tead2	TEA domain family member 2	0.131
Prph	peripherin	0.131
Myo1g	myosin IG	0.131
Fgl2	fibrinogen-like protein 2	0.131	Mouse
Ifnar2	interferon (alpha and beta) receptor 2	0.131
Entpd1	ectonucleoside triphosphate diphosphohydrolase 1	0.131
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.130
Zbtb16	zinc finger and BTB domain containing 16	0.130
Fbrs	fibrosin	0.130
Casp14	caspase 14	0.130	Mouse