IMP: Integrative Multi-species Prediction

Mus musculus

100 genes annotated in mouse

mesoderm development

The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "mesoderm development"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "mesoderm development" (in gray)

Name	Description	Probability	Func Analog Organism
Shh	sonic hedgehog	1.000
Ctnnb1	catenin (cadherin associated protein), beta 1	1.000
Gli3	GLI-Kruppel family member GLI3	1.000
Fgfr2	fibroblast growth factor receptor 2	1.000	Zebrafish Mouse Rat Fly
Otx2	orthodenticle homolog 2 (Drosophila)	1.000
Nodal	nodal	0.999
Emx1	empty spiracles homolog 1 (Drosophila)	0.998
Msx1	homeobox, msh-like 1	0.997
Sox2	SRY-box containing gene 2	0.997	Mouse
Pitx2	paired-like homeodomain transcription factor 2	0.997	Zebrafish
Foxc1	forkhead box C1	0.995
Pax2	paired box gene 2	0.994
Pax6	paired box gene 6	0.994
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.993	Mouse
Fgfr1	fibroblast growth factor receptor 1	0.992
Bmp4	bone morphogenetic protein 4	0.991
Hand1	heart and neural crest derivatives expressed transcript 1	0.990
Tbx1	T-box 1	0.989
Lef1	lymphoid enhancer binding factor 1	0.987
Lmx1b	LIM homeobox transcription factor 1 beta	0.986	Mouse
Apc	adenomatosis polyposis coli	0.985
Foxc2	forkhead box C2	0.983
Foxg1	forkhead box G1	0.983	Mouse
Notch1	Notch gene homolog 1 (Drosophila)	0.970	Zebrafish Fly
Hes1	hairy and enhancer of split 1 (Drosophila)	0.970
Foxh1	forkhead box H1	0.961
Lhx1	LIM homeobox protein 1	0.957	Mouse
Sall4	sal-like 4 (Drosophila)	0.956	Mouse Worm
Pax3	paired box gene 3	0.956
Pbx1	pre B-cell leukemia transcription factor 1	0.956	Worm
Hand2	heart and neural crest derivatives expressed transcript 2	0.953	Mouse
Pou5f1	POU domain, class 5, transcription factor 1	0.946
Tlx3	T-cell leukemia, homeobox 3	0.938	Mouse
Zeb1	zinc finger E-box binding homeobox 1	0.936	Fly
Emx2	empty spiracles homolog 2 (Drosophila)	0.936
Eya1	eyes absent 1 homolog (Drosophila)	0.931
Meox2	mesenchyme homeobox 2	0.923
Tcfap2a	transcription factor AP-2, alpha	0.914
Wt1	Wilms tumor 1 homolog	0.911
Zic3	zinc finger protein of the cerebellum 3	0.909
Fgf8	fibroblast growth factor 8	0.892
Foxf1a	forkhead box F1a	0.885
Chd7	chromodomain helicase DNA binding protein 7	0.884
Alx4	aristaless-like homeobox 4	0.883
Prrx1	paired related homeobox 1	0.880
Pax9	paired box gene 9	0.874	Mouse
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.868
Tgfb2	transforming growth factor, beta 2	0.858
Msx2	homeobox, msh-like 2	0.853
Hoxa1	homeobox A1	0.853
Efnb2	ephrin B2	0.850
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.849	Mouse Worm Fly
Gas1	growth arrest specific 1	0.838
Snai1	snail homolog 1 (Drosophila)	0.837
Hoxd11	homeobox D11	0.837	Mouse
Gdnf	glial cell line derived neurotrophic factor	0.824
En1	engrailed 1	0.820
Wnt3a	wingless-related MMTV integration site 3A	0.815
Sfrp2	secreted frizzled-related protein 2	0.812
Tbx3	T-box 3	0.810	Human Mouse
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.804
Bdnf	brain derived neurotrophic factor	0.800
Pou3f3	POU domain, class 3, transcription factor 3	0.800	Mouse
Gsc	goosecoid homeobox	0.797
Hoxa13	homeobox A13	0.794
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.793
Lhx3	LIM homeobox protein 3	0.778	Mouse
Fgf10	fibroblast growth factor 10	0.775
Fgf15	fibroblast growth factor 15	0.774
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.753
Hoxd13	homeobox D13	0.741
Meis2	Meis homeobox 2	0.736	Worm
Bcl2	B-cell leukemia/lymphoma 2	0.729
Crb2	crumbs homolog 2 (Drosophila)	0.718
Neurog2	neurogenin 2	0.704	Mouse
Pthlh	parathyroid hormone-like peptide	0.698
Sox9	SRY-box containing gene 9	0.695	Mouse
Smad6	MAD homolog 6 (Drosophila)	0.692	Mouse
Psen1	presenilin 1	0.692
Pitx1	paired-like homeodomain transcription factor 1	0.677
Bmp7	bone morphogenetic protein 7	0.669
Gbx2	gastrulation brain homeobox 2	0.660
Gli2	GLI-Kruppel family member GLI2	0.658
Dlx5	distal-less homeobox 5	0.650
Twist2	twist homolog 2 (Drosophila)	0.631	Mouse Worm Fly
Amhr2	anti-Mullerian hormone type 2 receptor	0.628	Mouse
Hoxd9	homeobox D9	0.627
Nkx2-1	NK2 homeobox 1	0.622
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.614
Rarb	retinoic acid receptor, beta	0.612
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.608
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.597
Sox3	SRY-box containing gene 3	0.578	Mouse
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.575	Zebrafish
Robo1	roundabout homolog 1 (Drosophila)	0.569
Wnt4	wingless-related MMTV integration site 4	0.549	Mouse
Mecom	MDS1 and EVI1 complex locus	0.548
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.545
Wnt1	wingless-related MMTV integration site 1	0.542	Mouse Fly
Rarg	retinoic acid receptor, gamma	0.538	Zebrafish
Vangl2	vang-like 2 (van gogh, Drosophila)	0.537
Vax1	ventral anterior homeobox containing gene 1	0.531
Vegfa	vascular endothelial growth factor A	0.525
Sox7	SRY-box containing gene 7	0.523	Mouse
Gata4	GATA binding protein 4	0.518
Dll1	delta-like 1 (Drosophila)	0.518	Zebrafish Mouse Fly
Lefty1	left right determination factor 1	0.516	Zebrafish
Notch2	Notch gene homolog 2 (Drosophila)	0.513	Fly
Hes5	hairy and enhancer of split 5 (Drosophila)	0.508	Fly
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.508
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.507
Lama5	laminin, alpha 5	0.507	Fly
Foxe3	forkhead box E3	0.502	Mouse
Pitx3	paired-like homeodomain transcription factor 3	0.502
Smad7	MAD homolog 7 (Drosophila)	0.501	Mouse
Pou3f4	POU domain, class 3, transcription factor 4	0.497	Mouse
Foxf2	forkhead box F2	0.493	Mouse
Acvr1	activin A receptor, type 1	0.490
Hdac7	histone deacetylase 7	0.486
Nog	noggin	0.477
Gsk3b	glycogen synthase kinase 3 beta	0.476
Runx1t1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.473
Acvr2a	activin receptor IIA	0.459
Atoh7	atonal homolog 7 (Drosophila)	0.458	Mouse
Otx1	orthodenticle homolog 1 (Drosophila)	0.455
Efna4	ephrin A4	0.452
Des	desmin	0.449
Yap1	yes-associated protein 1	0.444
Inhbb	inhibin beta-B	0.442	Mouse
Tcf15	transcription factor 15	0.437
Bmp5	bone morphogenetic protein 5	0.436	Mouse Fly
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.435	Human
Lmx1a	LIM homeobox transcription factor 1 alpha	0.426	Mouse
Eomes	eomesodermin homolog (Xenopus laevis)	0.421
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.420
Smad4	MAD homolog 4 (Drosophila)	0.416
Nes	nestin	0.413
Hoxa9	homeobox A9	0.410
Slit3	slit homolog 3 (Drosophila)	0.409	Fly
Sall1	sal-like 1 (Drosophila)	0.407
Lhx5	LIM homeobox protein 5	0.406	Mouse
Axin1	axin 1	0.400
Efs	embryonal Fyn-associated substrate	0.400
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.399
Hoxa5	homeobox A5	0.399
Dll4	delta-like 4 (Drosophila)	0.396	Mouse Fly
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.394
Hoxa4	homeobox A4	0.391
Lrp6	low density lipoprotein receptor-related protein 6	0.388
Tead1	TEA domain family member 1	0.388
Tbx2	T-box 2	0.385	Mouse
Sox11	SRY-box containing gene 11	0.385	Mouse
Twsg1	twisted gastrulation homolog 1 (Drosophila)	0.383
Bnc1	basonuclin 1	0.382
Esrrb	estrogen related receptor, beta	0.382
Prrx2	paired related homeobox 2	0.382
Shox2	short stature homeobox 2	0.381
Insm1	insulinoma-associated 1	0.379
Gdf1	growth differentiation factor 1	0.376
Tbx6	T-box 6	0.374
Hoxa11	homeobox A11	0.372
Nr2e1	nuclear receptor subfamily 2, group E, member 1	0.370
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.367
Pax7	paired box gene 7	0.366
Ntn1	netrin 1	0.366	Worm
Uncx	UNC homeobox	0.355
Cdx1	caudal type homeobox 1	0.354
Gdf11	growth differentiation factor 11	0.354
Mta1	metastasis associated 1	0.344	Worm
Isl1	ISL1 transcription factor, LIM/homeodomain	0.341	Mouse
Tgfbr2	transforming growth factor, beta receptor II	0.339	Mouse
Smo	smoothened homolog (Drosophila)	0.339
Ilk	integrin linked kinase	0.333
Nr0b1	nuclear receptor subfamily 0, group B, member 1	0.333
Wnt7b	wingless-related MMTV integration site 7B	0.332	Mouse
Tead3	TEA domain family member 3	0.328
Smad5	MAD homolog 5 (Drosophila)	0.326	Mouse
Barx1	BarH-like homeobox 1	0.323
Npr3	natriuretic peptide receptor 3	0.318
Tbx15	T-box 15	0.309	Mouse
T	brachyury	0.304
Hic1	hypermethylated in cancer 1	0.300
Pou4f2	POU domain, class 4, transcription factor 2	0.300	Mouse
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.298	Mouse
Phlda2	pleckstrin homology-like domain, family A, member 2	0.295
Tcf4	transcription factor 4	0.295
Vcl	vinculin	0.294
Fgf4	fibroblast growth factor 4	0.292
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.291	Mouse
Crebbp	CREB binding protein	0.282
Foxa2	forkhead box A2	0.277	Zebrafish Mouse
Tcfap2b	transcription factor AP-2 beta	0.276
Nkx2-4	NK2 transcription factor related, locus 4 (Drosophila)	0.273
Foxb1	forkhead box B1	0.272
Wnt6	wingless-related MMTV integration site 6	0.268	Mouse
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.258
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.249
Wnt5a	wingless-related MMTV integration site 5A	0.249	Mouse
Tcfap2c	transcription factor AP-2, gamma	0.249
Smad2	MAD homolog 2 (Drosophila)	0.248
Tcf21	transcription factor 21	0.248
Nkx3-2	NK3 homeobox 2	0.246	Fly
Fzd9	frizzled homolog 9 (Drosophila)	0.244
Ptk2	PTK2 protein tyrosine kinase 2	0.243
Adcyap1	adenylate cyclase activating polypeptide 1	0.240
Padi3	peptidyl arginine deiminase, type III	0.240
Lhx4	LIM homeobox protein 4	0.240	Mouse
En2	engrailed 2	0.239
Dmbx1	diencephalon/mesencephalon homeobox 1	0.234
Drd2	dopamine receptor D2	0.234
Htt	huntingtin	0.232
Ptk7	PTK7 protein tyrosine kinase 7	0.231
Atoh1	atonal homolog 1 (Drosophila)	0.230	Mouse
Hoxd12	homeobox D12	0.228	Fly
Slit2	slit homolog 2 (Drosophila)	0.225	Fly
Foxd1	forkhead box D1	0.222	Mouse
Cer1	cerberus 1 homolog (Xenopus laevis)	0.216
Hoxb13	homeobox B13	0.215
Tlx2	T-cell leukemia, homeobox 2	0.214
App	amyloid beta (A4) precursor protein	0.212
Kitl	kit ligand	0.211
Runx2	runt related transcription factor 2	0.211
Inhba	inhibin beta-A	0.209
Foxd3	forkhead box D3	0.208	Mouse
Epb4.1l5	erythrocyte protein band 4.1-like 5	0.208
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.207
Rara	retinoic acid receptor, alpha	0.207
Twist1	twist homolog 1 (Drosophila)	0.205	Mouse Worm Fly
Efnb1	ephrin B1	0.205
Fshr	follicle stimulating hormone receptor	0.204
Pdgfb	platelet derived growth factor, B polypeptide	0.202	Mouse
She	src homology 2 domain-containing transforming protein E	0.202
Ptf1a	pancreas specific transcription factor, 1a	0.201	Mouse
Ephb3	Eph receptor B3	0.201	Mouse
Rac1	RAS-related C3 botulinum substrate 1	0.199	Fly
Smad1	MAD homolog 1 (Drosophila)	0.199
Ednra	endothelin receptor type A	0.199
Wnt3	wingless-related MMTV integration site 3	0.198
Nanog	Nanog homeobox	0.196
Zfp703	zinc finger protein 703	0.195
Tcf7	transcription factor 7, T-cell specific	0.194	Mouse Worm
Nfib	nuclear factor I/B	0.194
Fgf3	fibroblast growth factor 3	0.193
Evx2	even skipped homeotic gene 2 homolog	0.193
Irx6	Iroquois related homeobox 6 (Drosophila)	0.192
Bmp6	bone morphogenetic protein 6	0.190	Mouse Fly
Mef2c	myocyte enhancer factor 2C	0.189	Fly
Tead2	TEA domain family member 2	0.189
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.188
Kiss1	KiSS-1 metastasis-suppressor	0.188
Acvr2b	activin receptor IIB	0.187
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.187
Fst	follistatin	0.186
Btbd17	BTB (POZ) domain containing 17	0.186
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.184
Adra2b	adrenergic receptor, alpha 2b	0.184
Eng	endoglin	0.184
Cd151	CD151 antigen	0.183
Gdf3	growth differentiation factor 3	0.183
Ddr2	discoidin domain receptor family, member 2	0.181
Tshz1	teashirt zinc finger family member 1	0.180
Flt4	FMS-like tyrosine kinase 4	0.180
Foxa1	forkhead box A1	0.177	Zebrafish Mouse
Emp2	epithelial membrane protein 2	0.177
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.176	Fly
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.176
Pls3	plastin 3 (T-isoform)	0.176
Wwc2	WW, C2 and coiled-coil domain containing 2	0.172
Sox21	SRY-box containing gene 21	0.169
Meox1	mesenchyme homeobox 1	0.165
Glra1	glycine receptor, alpha 1 subunit	0.164
Cyr61	cysteine rich protein 61	0.163
Hoxa2	homeobox A2	0.162
Sox1	SRY-box containing gene 1	0.162
Pou3f2	POU domain, class 3, transcription factor 2	0.160	Mouse
Fermt2	fermitin family homolog 2 (Drosophila)	0.159
Alx1	ALX homeobox 1	0.159
Kif3a	kinesin family member 3A	0.156
Bptf	bromodomain PHD finger transcription factor	0.155
Matn3	matrilin 3	0.154
Mnx1	motor neuron and pancreas homeobox 1	0.154
Sim2	single-minded homolog 2 (Drosophila)	0.154
Sim1	single-minded homolog 1 (Drosophila)	0.154
Cdx2	caudal type homeobox 2	0.152
Sall3	sal-like 3 (Drosophila)	0.151	Mouse Worm
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.150	Zebrafish
Irx1	Iroquois related homeobox 1 (Drosophila)	0.148	Mouse
Hoxc6	homeobox C6	0.147
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.145	Mouse
Gli1	GLI-Kruppel family member GLI1	0.144
Myf5	myogenic factor 5	0.144
Col4a3	collagen, type IV, alpha 3	0.143
Smad9	MAD homolog 9 (Drosophila)	0.143	Mouse
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.143
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.142
Bmp2	bone morphogenetic protein 2	0.142	Zebrafish Mouse Fly
Tal1	T-cell acute lymphocytic leukemia 1	0.140
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.140
Robo2	roundabout homolog 2 (Drosophila)	0.139
Arx	aristaless related homeobox	0.137
Lhb	luteinizing hormone beta	0.137
Rdh10	retinol dehydrogenase 10 (all-trans)	0.137
Aldoa	aldolase A, fructose-bisphosphate	0.136
Nf2	neurofibromatosis 2	0.135
Sox14	SRY-box containing gene 14	0.134
Tead4	TEA domain family member 4	0.134	Mouse
Numb	numb gene homolog (Drosophila)	0.133
Evx1	even skipped homeotic gene 1 homolog	0.133
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.132
Pten	phosphatase and tensin homolog	0.132
Pax1	paired box gene 1	0.131	Mouse
Hoxb5	homeobox B5	0.131
Pax8	paired box gene 8	0.131	Mouse
Hoxb1	homeobox B1	0.131
Il11	interleukin 11	0.130
Epn3	epsin 3	0.130
Chrna7	cholinergic receptor, nicotinic, alpha polypeptide 7	0.128
Hnf1b	HNF1 homeobox B	0.127	Mouse
Hoxb4	homeobox B4	0.127
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.126	Mouse Worm Fly
Pds5b	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.126
Ush1g	Usher syndrome 1G homolog (human)	0.126
Emid2	EMI domain containing 2	0.126
Hoxd1	homeobox D1	0.126
Traf6	TNF receptor-associated factor 6	0.126
Bcl6b	B-cell CLL/lymphoma 6, member B	0.125
Zfp651	zinc finger protein 651	0.124
Neurog1	neurogenin 1	0.123	Mouse
Jag2	jagged 2	0.123	Mouse
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.122
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.122
Neurod1	neurogenic differentiation 1	0.120	Mouse
Wls	wntless homolog (Drosophila)	0.120
Lhx9	LIM homeobox protein 9	0.119	Mouse
Adra2a	adrenergic receptor, alpha 2a	0.119
Mta2	metastasis-associated gene family, member 2	0.117	Worm
Adra2c	adrenergic receptor, alpha 2c	0.117
Cdh5	cadherin 5	0.117
Edn3	endothelin 3	0.115
Aicda	activation-induced cytidine deaminase	0.115
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.114
Htr4	5 hydroxytryptamine (serotonin) receptor 4	0.114
Phox2b	paired-like homeobox 2b	0.114
Pdgfa	platelet derived growth factor, alpha	0.114	Mouse
Prop1	paired like homeodomain factor 1	0.114
Hoxc8	homeobox C8	0.113
Hdac4	histone deacetylase 4	0.113
Dlg1	discs, large homolog 1 (Drosophila)	0.113
Tnks1bp1	tankyrase 1 binding protein 1	0.113
Hes3	hairy and enhancer of split 3 (Drosophila)	0.113	Fly
Gdf5	growth differentiation factor 5	0.112	Mouse
Fgfr3	fibroblast growth factor receptor 3	0.112	Mouse Fly
Fosb	FBJ osteosarcoma oncogene B	0.112
Col13a1	collagen, type XIII, alpha 1	0.111
Fhl3	four and a half LIM domains 3	0.111
Zfp503	zinc finger protein 503	0.111
Hdac1	histone deacetylase 1	0.110
Wnt10a	wingless related MMTV integration site 10a	0.110
Robo3	roundabout homolog 3 (Drosophila)	0.110
Dlx3	distal-less homeobox 3	0.109
Hoxd3	homeobox D3	0.109
Mef2d	myocyte enhancer factor 2D	0.108	Fly
Nphs2	nephrosis 2 homolog, podocin (human)	0.107
Ephb2	Eph receptor B2	0.107	Mouse
Usp43	ubiquitin specific peptidase 43	0.107
Fign	fidgetin	0.106
Tcfcp2l1	transcription factor CP2-like 1	0.106
Irx2	Iroquois related homeobox 2 (Drosophila)	0.105	Mouse
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.104
BC024139	cDNA sequence BC024139	0.104
Kcnk3	potassium channel, subfamily K, member 3	0.104
Itgb4	integrin beta 4	0.102	Human
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.102	Mouse
Ctnnd1	catenin (cadherin associated protein), delta 1	0.101
Myo1c	myosin IC	0.101	Fly
Fbln1	fibulin 1	0.100
Hoxb6	homeobox B6	0.100
Fgf16	fibroblast growth factor 16	0.099
Kcnh3	potassium voltage-gated channel, subfamily H (eag-related), member 3	0.098
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.098
Mmp24	matrix metallopeptidase 24	0.098
Egr1	early growth response 1	0.098
Aif1l	allograft inflammatory factor 1-like	0.097
Crlf1	cytokine receptor-like factor 1	0.096
Fgf18	fibroblast growth factor 18	0.096	Mouse
Col2a1	collagen, type II, alpha 1	0.096
Cbx2	chromobox homolog 2 (Drosophila Pc class)	0.096
Sox13	SRY-box containing gene 13	0.096
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.096
Amh	anti-Mullerian hormone	0.095
Fgf20	fibroblast growth factor 20	0.095
Hesx1	homeobox gene expressed in ES cells	0.095
Efna2	ephrin A2	0.094
Chst2	carbohydrate sulfotransferase 2	0.094
Slit1	slit homolog 1 (Drosophila)	0.093	Fly
Lbx2	ladybird homeobox homolog 2 (Drosophila)	0.093
Acan	aggrecan	0.092
Slc12a2	solute carrier family 12, member 2	0.092
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.092
Tbx4	T-box 4	0.092	Mouse
Hmx3	H6 homeobox 3	0.091	Worm
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.091
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.091
Krtdap	keratinocyte differentiation associated protein	0.090
Isl2	insulin related protein 2 (islet 2)	0.090	Mouse
Lhx6	LIM homeobox protein 6	0.090	Mouse
Mesp1	mesoderm posterior 1	0.090
Irs1	insulin receptor substrate 1	0.089
Fzd8	frizzled homolog 8 (Drosophila)	0.089
Fgf5	fibroblast growth factor 5	0.088
Ctnna1	catenin (cadherin associated protein), alpha 1	0.088
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.088
Grem1	gremlin 1	0.088	Mouse
Hoxb7	homeobox B7	0.087
Gpr3	G-protein coupled receptor 3	0.086
Gata3	GATA binding protein 3	0.086
Hoxc5	homeobox C5	0.086
Smad3	MAD homolog 3 (Drosophila)	0.086
Sema3b	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	0.086
Gata5	GATA binding protein 5	0.085
Hnf4a	hepatic nuclear factor 4, alpha	0.085
Adrb1	adrenergic receptor, beta 1	0.085
Prx	periaxin	0.084
Krt84	keratin 84	0.084
Nkx2-9	NK2 transcription factor related, locus 9 (Drosophila)	0.084
Nobox	NOBOX oogenesis homeobox	0.083
Tgfbr3	transforming growth factor, beta receptor III	0.083
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.082
Ldb1	LIM domain binding 1	0.082
Nrtn	neurturin	0.082
Cilp2	cartilage intermediate layer protein 2	0.081
Lrp2	low density lipoprotein receptor-related protein 2	0.081
Bhlha9	basic helix-loop-helix family, member a9	0.081
Theg	testicular haploid expressed gene	0.081
Neurod4	neurogenic differentiation 4	0.080	Mouse
Fzd2	frizzled homolog 2 (Drosophila)	0.080
Myog	myogenin	0.080
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.080
Prkcc	protein kinase C, gamma	0.080
Dlx1	distal-less homeobox 1	0.079
Igbp1	immunoglobulin (CD79A) binding protein 1	0.079
Fzd10	frizzled homolog 10 (Drosophila)	0.078
Foxj1	forkhead box J1	0.078
Krt85	keratin 85	0.076
Dach1	dachshund 1 (Drosophila)	0.076
Sp8	trans-acting transcription factor 8	0.076
Tsc1	tuberous sclerosis 1	0.076
Hdac2	histone deacetylase 2	0.075
Ccr10	chemokine (C-C motif) receptor 10	0.075
Lbx1	ladybird homeobox homolog 1 (Drosophila)	0.075
Ngf	nerve growth factor	0.074
Wnt2b	wingless related MMTV integration site 2b	0.074	Mouse
Ebf2	early B-cell factor 2	0.074
Dnahc11	dynein, axonemal, heavy chain 11	0.074
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.074
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.073
Cacng7	calcium channel, voltage-dependent, gamma subunit 7	0.072
Cfc1	cripto, FRL-1, cryptic family 1	0.072	Zebrafish
Dbx1	developing brain homeobox 1	0.072
Srebf2	sterol regulatory element binding factor 2	0.072
Utf1	undifferentiated embryonic cell transcription factor 1	0.072
Nfatc1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.071
Sfrp5	secreted frizzled-related sequence protein 5	0.071	Mouse
Cdh11	cadherin 11	0.071
Rfx2	regulatory factor X, 2 (influences HLA class II expression)	0.071
Bik	BCL2-interacting killer	0.071
Epha4	Eph receptor A4	0.071	Mouse
Gata2	GATA binding protein 2	0.071
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.070
Ssbp3	single-stranded DNA binding protein 3	0.070
Smarcc1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.069
Snai2	snail homolog 2 (Drosophila)	0.069	Mouse
Nkx6-1	NK6 homeobox 1	0.069
Rgnef	Rho-guanine nucleotide exchange factor	0.069
Irx3	Iroquois related homeobox 3 (Drosophila)	0.069
Col12a1	collagen, type XII, alpha 1	0.068
Mdm4	transformed mouse 3T3 cell double minute 4	0.068
Scn5a	sodium channel, voltage-gated, type V, alpha	0.068
Cabp2	calcium binding protein 2	0.068
Nf1	neurofibromatosis 1	0.068
Lyzl4	lysozyme-like 4	0.068
Ldb2	LIM domain binding 2	0.068
Stk3	serine/threonine kinase 3 (Ste20, yeast homolog)	0.068
Hist1h1t	histone cluster 1, H1t	0.067
Qk	quaking	0.067	Fly
Rnf111	ring finger 111	0.067
Otp	orthopedia homolog (Drosophila)	0.067
Hoxd8	homeobox D8	0.067
Maf	avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog	0.067
Cnpy1	canopy 1 homolog (zebrafish)	0.067
Wnt8b	wingless related MMTV integration site 8b	0.067	Mouse
Fgf6	fibroblast growth factor 6	0.066
Ccdc88a	coiled coil domain containing 88A	0.066
Hmga2	high mobility group AT-hook 2	0.066
Col25a1	collagen, type XXV, alpha 1	0.066
Dcc	deleted in colorectal carcinoma	0.066
Itgav	integrin alpha V	0.066
Lrp5	low density lipoprotein receptor-related protein 5	0.065
Actn4	actinin alpha 4	0.065
Actn2	actinin alpha 2	0.065
Nrarp	Notch-regulated ankyrin repeat protein	0.065
Amotl2	angiomotin-like 2	0.065
Lgals7	lectin, galactose binding, soluble 7	0.065
Insm2	insulinoma-associated 2	0.065
Gja4	gap junction protein, alpha 4	0.065
Myod1	myogenic differentiation 1	0.064
Ptpru	protein tyrosine phosphatase, receptor type, U	0.064
Tgfa	transforming growth factor alpha	0.064
Cox4i2	cytochrome c oxidase subunit IV isoform 2	0.064
Syngr4	synaptogyrin 4	0.064
Cyp26c1	cytochrome P450, family 26, subfamily c, polypeptide 1	0.064
Hoxa10	homeobox A10	0.064
Mecp2	methyl CpG binding protein 2	0.064
Zbtb46	zinc finger and BTB domain containing 46	0.064
Hoxa7	homeobox A7	0.064
Msx3	homeobox, msh-like 3	0.064
Oprm1	opioid receptor, mu 1	0.063
Tmeff2	transmembrane protein with EGF-like and two follistatin-like domains 2	0.063
Fgf17	fibroblast growth factor 17	0.063	Zebrafish Mouse
Plec	plectin	0.063	Mouse
Jag1	jagged 1	0.063	Mouse
4931408A02Rik	RIKEN cDNA 4931408A02 gene	0.062
Cnn1	calponin 1	0.062
Tll2	tolloid-like 2	0.062	Zebrafish
Skor1	SKI family transcriptional corepressor 1	0.062
Zic2	zinc finger protein of the cerebellum 2	0.062
Pkdcc	protein kinase domain containing, cytoplasmic	0.062
F2r	coagulation factor II (thrombin) receptor	0.062
Ptch2	patched homolog 2	0.061
Adamtsl5	ADAMTS-like 5	0.061
Rax	retina and anterior neural fold homeobox	0.061
Klk4	kallikrein related-peptidase 4 (prostase, enamel matrix, prostate)	0.061
Slc22a6	solute carrier family 22 (organic anion transporter), member 6	0.061
Smtn	smoothelin	0.061
Hoxc13	homeobox C13	0.060
Pkd1	polycystic kidney disease 1 homolog	0.060
Fzd1	frizzled homolog 1 (Drosophila)	0.060
Ntn3	netrin 3	0.060
Cd22	CD22 antigen	0.059
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.059
Plcd1	phospholipase C, delta 1	0.059
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.059
Lefty2	left-right determination factor 2	0.059	Zebrafish
Angpt1	angiopoietin 1	0.058
Gsx1	GS homeobox 1	0.058
Foxb2	forkhead box B2	0.058	Mouse
Vstm2b	V-set and transmembrane domain containing 2B	0.058
Epha3	Eph receptor A3	0.058	Mouse
Prph2	peripherin 2	0.058
Slc25a29	solute carrier family 25 (mitochondrial carrier, palmitoylcarnitine transporter), member 29	0.057
Hhex	hematopoietically expressed homeobox	0.057
Hoxb9	homeobox B9	0.057
Chad	chondroadherin	0.057
Nxph4	neurexophilin 4	0.057
Cdh13	cadherin 13	0.057
Rhbdl3	rhomboid, veinlet-like 3 (Drosophila)	0.057
Fjx1	four jointed box 1 (Drosophila)	0.057
Pkm2	pyruvate kinase, muscle	0.056
Neurog3	neurogenin 3	0.056	Mouse
Irx5	Iroquois related homeobox 5 (Drosophila)	0.056	Mouse
Atoh8	atonal homolog 8 (Drosophila)	0.056
Foxn4	forkhead box N4	0.056
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.056	Mouse
Sox18	SRY-box containing gene 18	0.056	Mouse
Dusp9	dual specificity phosphatase 9	0.056
Ankrd2	ankyrin repeat domain 2 (stretch responsive muscle)	0.056
Cxcl14	chemokine (C-X-C motif) ligand 14	0.056
Itga5	integrin alpha 5 (fibronectin receptor alpha)	0.056
Cnbp	cellular nucleic acid binding protein	0.056
Kdr	kinase insert domain protein receptor	0.055
Rbpjl	recombination signal binding protein for immunoglobulin kappa J region-like	0.055
Lmod1	leiomodin 1 (smooth muscle)	0.055
Unc5c	unc-5 homolog C (C. elegans)	0.055	Worm
Tcf12	transcription factor 12	0.055
Smn1	survival motor neuron 1	0.055
Sh3rf1	SH3 domain containing ring finger 1	0.055
Lalba	lactalbumin, alpha	0.055
Nhlh2	nescient helix loop helix 2	0.054	Mouse
Ihh	Indian hedgehog	0.054	Mouse Fly
Fli1	Friend leukemia integration 1	0.054
Esx1	extraembryonic, spermatogenesis, homeobox 1	0.054
Csf1	colony stimulating factor 1 (macrophage)	0.054
Phlda3	pleckstrin homology-like domain, family A, member 3	0.053
Zbtb7c	zinc finger and BTB domain containing 7C	0.053
Hoxc9	homeobox C9	0.053
Ninj2	ninjurin 2	0.053
Lims1	LIM and senescent cell antigen-like domains 1	0.053
Pou3f1	POU domain, class 3, transcription factor 1	0.053	Mouse
Zfhx3	zinc finger homeobox 3	0.053
Htr1b	5-hydroxytryptamine (serotonin) receptor 1B	0.053
Zfhx4	zinc finger homeodomain 4	0.053
Pknox1	Pbx/knotted 1 homeobox	0.053
Zp3	zona pellucida glycoprotein 3	0.053
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.053
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.053	Mouse Worm
Mn1	meningioma 1	0.053
Vmn2r26	vomeronasal 2, receptor 26	0.053
Arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.053
Bmp8a	bone morphogenetic protein 8a	0.052	Mouse Fly
Sorcs3	sortilin-related VPS10 domain containing receptor 3	0.052
Gipc3	GIPC PDZ domain containing family, member 3	0.052
Kcnj6	potassium inwardly-rectifying channel, subfamily J, member 6	0.052
Phldb2	pleckstrin homology-like domain, family B, member 2	0.052
Klf7	Kruppel-like factor 7 (ubiquitous)	0.052
Notch3	Notch gene homolog 3 (Drosophila)	0.051	Fly
Gm5506	predicted gene 5506	0.051
Wnt11	wingless-related MMTV integration site 11	0.051	Mouse
Gata6	GATA binding protein 6	0.051
Irs3	insulin receptor substrate 3	0.051
Srrm4	serine/arginine repetitive matrix 4	0.051
Huwe1	HECT, UBA and WWE domain containing 1	0.051
Cldn3	claudin 3	0.051
Arc	activity regulated cytoskeletal-associated protein	0.051
Gaa	glucosidase, alpha, acid	0.050
Bhlhe23	basic helix-loop-helix family, member e23	0.050
Avp	arginine vasopressin	0.050
Grid2ip	glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1	0.050
Rasip1	Ras interacting protein 1	0.050
Glis1	GLIS family zinc finger 1	0.050
9430031J16Rik	RIKEN cDNA 9430031J16 gene	0.049
Krt71	keratin 71	0.049
Jup	junction plakoglobin	0.049
Ccdc24	coiled-coil domain containing 24	0.049
Rspo1	R-spondin homolog (Xenopus laevis)	0.049
Mef2a	myocyte enhancer factor 2A	0.049	Fly
Hmx1	H6 homeobox 1	0.049	Worm
Zyx	zyxin	0.049
Tlx1	T-cell leukemia, homeobox 1	0.049	Mouse
C77681	expressed sequence C77681	0.049
Lag3	lymphocyte-activation gene 3	0.049
Prss12	protease, serine, 12 neurotrypsin (motopsin)	0.049
5730559C18Rik	RIKEN cDNA 5730559C18 gene	0.049
Wnt10b	wingless related MMTV integration site 10b	0.049	Mouse
Chrm1	cholinergic receptor, muscarinic 1, CNS	0.048
Arid1a	AT rich interactive domain 1A (SWI-like)	0.048
Slc32a1	solute carrier family 32 (GABA vesicular transporter), member 1	0.048
Rere	arginine glutamic acid dipeptide (RE) repeats	0.048
Ncor2	nuclear receptor co-repressor 2	0.048
Stag1	stromal antigen 1	0.048
Plcb3	phospholipase C, beta 3	0.048
Lrrc58	leucine rich repeat containing 58	0.048
Clcn1	chloride channel 1	0.048
Tle4	transducin-like enhancer of split 4, homolog of Drosophila E(spl)	0.048
Vgll2	vestigial like 2 homolog (Drosophila)	0.047
Egln1	EGL nine homolog 1 (C. elegans)	0.047
Cdc42ep1	CDC42 effector protein (Rho GTPase binding) 1	0.047
Skil	SKI-like	0.047
Duoxa1	dual oxidase maturation factor 1	0.047
Spna2	spectrin alpha 2	0.047
Zmynd11	zinc finger, MYND domain containing 11	0.047
Nr4a2	nuclear receptor subfamily 4, group A, member 2	0.047	Mouse
Hipk3	homeodomain interacting protein kinase 3	0.047
Neurod6	neurogenic differentiation 6	0.047	Mouse
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.047
Plcg1	phospholipase C, gamma 1	0.047
Naa11	N(alpha)-acetyltransferase 11, NatA catalytic subunit	0.047
Bcar1	breast cancer anti-estrogen resistance 1	0.047
Flnc	filamin C, gamma	0.046
Hdac5	histone deacetylase 5	0.046
Cux2	cut-like homeobox 2	0.046
Mib1	mindbomb homolog 1 (Drosophila)	0.046
Art5	ADP-ribosyltransferase 5	0.046
Pyy	peptide YY	0.046
Cldn5	claudin 5	0.046
Zeb2	zinc finger E-box binding homeobox 2	0.046	Fly
Tnfrsf25	tumor necrosis factor receptor superfamily, member 25	0.046
Ext1	exostoses (multiple) 1	0.046
Upk3b	uroplakin 3B	0.046
Klf4	Kruppel-like factor 4 (gut)	0.046
Vasp	vasodilator-stimulated phosphoprotein	0.046
Slc12a4	solute carrier family 12, member 4	0.046
Ppap2b	phosphatidic acid phosphatase type 2B	0.046
Gjc2	gap junction protein, gamma 2	0.046
Foxq1	forkhead box Q1	0.046	Mouse Worm Fly
Dennd5a	DENN/MADD domain containing 5A	0.045
Dlx2	distal-less homeobox 2	0.045
Hnrnpk	heterogeneous nuclear ribonucleoprotein K	0.045
Sftpc	surfactant associated protein C	0.045
Cenpj	centromere protein J	0.045
Kremen1	kringle containing transmembrane protein 1	0.045
Colq	collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase	0.045
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.045
Etl4	enhancer trap locus 4	0.045
Mab21l2	mab-21-like 2 (C. elegans)	0.045
Pygo1	pygopus 1	0.045
Gpc3	glypican 3	0.045
Mip	major intrinsic protein of eye lens fiber	0.045
Cpeb3	cytoplasmic polyadenylation element binding protein 3	0.045
Thbd	thrombomodulin	0.044
Hivep2	human immunodeficiency virus type I enhancer binding protein 2	0.044
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.044
Angptl2	angiopoietin-like 2	0.044
Hnf1a	HNF1 homeobox A	0.044
Mybph	myosin binding protein H	0.044
Creb1	cAMP responsive element binding protein 1	0.044
Hoxd4	homeobox D4	0.044
Sfrp1	secreted frizzled-related protein 1	0.044	Mouse
Cdh10	cadherin 10	0.044
Apc2	adenomatosis polyposis coli 2	0.044
Snai3	snail homolog 3 (Drosophila)	0.044	Mouse
Kank2	KN motif and ankyrin repeat domains 2	0.044
Epas1	endothelial PAS domain protein 1	0.043
Prkg2	protein kinase, cGMP-dependent, type II	0.043
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.043
Flt1	FMS-like tyrosine kinase 1	0.043
Clcnka	chloride channel Ka	0.043
Rapsn	receptor-associated protein of the synapse	0.043
Tdgf1	teratocarcinoma-derived growth factor 1	0.043	Zebrafish
Ptgdr	prostaglandin D receptor	0.043
Dmrt3	doublesex and mab-3 related transcription factor 3	0.043
Aplnr	apelin receptor	0.043	Zebrafish
Dll3	delta-like 3 (Drosophila)	0.043
Foxi1	forkhead box I1	0.043	Mouse
Zfp771	zinc finger protein 771	0.043
Itpkb	inositol 1,4,5-trisphosphate 3-kinase B	0.042
Dact3	dapper homolog 3, antagonist of beta-catenin (xenopus)	0.042
Aqp3	aquaporin 3	0.042
Ctbp2	C-terminal binding protein 2	0.042
Calca	calcitonin/calcitonin-related polypeptide, alpha	0.042
Figla	folliculogenesis specific basic helix-loop-helix	0.042
Ddx3y	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked	0.042
Chodl	chondrolectin	0.042
Flii	flightless I homolog (Drosophila)	0.042
Cdh16	cadherin 16	0.042
Lrrk2	leucine-rich repeat kinase 2	0.042
Fzd6	frizzled homolog 6 (Drosophila)	0.042
Axin2	axin2	0.041	Mouse
Pnoc	prepronociceptin	0.041
Cacng6	calcium channel, voltage-dependent, gamma subunit 6	0.041
Col8a1	collagen, type VIII, alpha 1	0.041
Tas1r1	taste receptor, type 1, member 1	0.041
Aebp1	AE binding protein 1	0.041
Hoxb2	homeobox B2	0.041
Prkci	protein kinase C, iota	0.041	Zebrafish
Prkaca	protein kinase, cAMP dependent, catalytic, alpha	0.041
Olfr71	olfactory receptor 71	0.041
Clasp1	CLIP associating protein 1	0.041
Tinagl1	tubulointerstitial nephritis antigen-like 1	0.041
BC057022	cDNA sequence BC057022	0.041
Slc5a5	solute carrier family 5 (sodium iodide symporter), member 5	0.041
Usp9x	ubiquitin specific peptidase 9, X chromosome	0.041
Socs1	suppressor of cytokine signaling 1	0.040
Rims4	regulating synaptic membrane exocytosis 4	0.040
Ephb6	Eph receptor B6	0.040	Mouse
Slc35e4	solute carrier family 35, member E4	0.040
Smoc2	SPARC related modular calcium binding 2	0.040
Adm	adrenomedullin	0.040
Whrn	whirlin	0.040
Kcnmb1	potassium large conductance calcium-activated channel, subfamily M, beta member 1	0.040
Mpdz	multiple PDZ domain protein	0.040