IMP
Process View
positive regulation of alkaline phosphatase activity
Any process that increases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.
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Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of alkaline phosphatase activity"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Hdac4 | histone deacetylase 4 | 0.438 | ||
| Pparg | peroxisome proliferator activated receptor gamma | 0.333 | ||
| Agtr2 | angiotensin II receptor, type 2 | 0.307 | ||
| Mef2c | myocyte enhancer factor 2C | 0.274 | ||
| Vdr | vitamin D receptor | 0.225 | ||
| Hdac7 | histone deacetylase 7 | 0.220 | ||
| Il6st | interleukin 6 signal transducer | 0.161 | ||
| Hdac5 | histone deacetylase 5 | 0.142 | ||
| Smad4 | MAD homolog 4 (Drosophila) | 0.129 | ||
| Mef2d | myocyte enhancer factor 2D | 0.096 | Mouse | |
| Lepr | leptin receptor | 0.091 | ||
| Apc | adenomatosis polyposis coli | 0.055 | ||
| Axin1 | axin 1 | 0.053 | ||
| Ttn | titin | 0.053 | ||
| Dmd | dystrophin, muscular dystrophy | 0.038 | ||
| Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.034 | ||
| Pten | phosphatase and tensin homolog | 0.033 | ||
| Gucy1b3 | guanylate cyclase 1, soluble, beta 3 | 0.031 | ||
| Cacna2d1 | calcium channel, voltage-dependent, alpha2/delta subunit 1 | 0.028 | ||
| Ncoa3 | nuclear receptor coactivator 3 | 0.025 | ||
| Qk | quaking | 0.025 | ||
| Pik3r1 | phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) | 0.024 | ||
| Larp1 | La ribonucleoprotein domain family, member 1 | 0.023 | ||
| Kif1b | kinesin family member 1B | 0.020 | ||
| Zbtb20 | zinc finger and BTB domain containing 20 | 0.020 | ||
| Tlr2 | toll-like receptor 2 | 0.019 | ||
| Zeb2 | zinc finger E-box binding homeobox 2 | 0.019 | ||
| Gucy1a3 | guanylate cyclase 1, soluble, alpha 3 | 0.019 | ||
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.018 | ||
| Ar | androgen receptor | 0.018 | ||
| Cav1 | caveolin 1, caveolae protein | 0.017 | ||
| Smad2 | MAD homolog 2 (Drosophila) | 0.016 | ||
| Tcf4 | transcription factor 4 | 0.016 | ||
| Usp10 | ubiquitin specific peptidase 10 | 0.015 | ||
| Hivep2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.015 | ||
| Ncoa1 | nuclear receptor coactivator 1 | 0.015 | ||
| Nfix | nuclear factor I/X | 0.015 | ||
| Tgfbr1 | transforming growth factor, beta receptor I | 0.015 | ||
| Ppp3ca | protein phosphatase 3, catalytic subunit, alpha isoform | 0.014 | ||
| Bcl2 | B-cell leukemia/lymphoma 2 | 0.014 | ||
| Vhl | von Hippel-Lindau tumor suppressor | 0.014 | ||
| Slc8a1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | 0.014 | ||
| Grwd1 | glutamate-rich WD repeat containing 1 | 0.014 | ||
| Smad5 | MAD homolog 5 (Drosophila) | 0.013 | ||
| Ank | progressive ankylosis | 0.013 | ||
| Trp53 | transformation related protein 53 | 0.013 | ||
| Spnb2 | spectrin beta 2 | 0.012 | ||
| Prkg1 | protein kinase, cGMP-dependent, type I | 0.012 | ||
| Vldlr | very low density lipoprotein receptor | 0.012 | ||
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.012 | ||
| Ank3 | ankyrin 3, epithelial | 0.012 | ||
| Rora | RAR-related orphan receptor alpha | 0.012 | ||
| Bmpr2 | bone morphogenic protein receptor, type II (serine/threonine kinase) | 0.012 | ||
| Gpm6b | glycoprotein m6b | 0.011 | ||
| Hdac9 | histone deacetylase 9 | 0.011 | ||
| St3gal2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 | 0.010 | ||
| Ebf1 | early B-cell factor 1 | 0.010 | ||
| Kitl | kit ligand | 0.010 |