IMP: Integrative Multi-species Prediction

Mus musculus

4 genes annotated in mouse

negative regulation of insulin secretion involved in cellular response to glucose stimulus

Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of insulin secretion involved in cellular response to glucose stimulus"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "negative regulation of insulin secretion involved in cellular response to glucose stimulus" (in gray)

Name	Description	Probability	Func Analog Organism
LOC100048884	novel member of the major urinary protein (Mup) gene family	1.000	Mouse
Mup9	major urinary protein 9	1.000	Mouse
Mup19	major urinary protein 19	1.000	Mouse
Mup10	major urinary protein 10	1.000	Mouse
Mup8	major urinary protein 8	1.000	Mouse
Mup12	major urinary protein 12	0.999	Mouse
Mup11	major urinary protein 11	0.999	Mouse
Mup1	major urinary protein 1	0.999
Mup5	major urinary protein 5	0.998	Mouse
Mup7	major urinary protein 7	0.998	Mouse
Mup13	major urinary protein 13	0.997
Mup14	major urinary protein 14	0.997	Mouse
Mup15	major urinary protein 15	0.997	Mouse
Mup17	major urinary protein 17	0.996
LOC100048885	major urinary protein LOC100048885	0.996	Mouse
Mup2	major urinary protein 2	0.994	Mouse
Pim2	proviral integration site 2	0.992	Mouse
Mup3	major urinary protein 3	0.988	Mouse
Mup4	major urinary protein 4	0.961	Mouse
Svs5	seminal vesicle secretory protein 5	0.937
Obp1a	odorant binding protein Ia	0.766	Mouse
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.545
Pim3	proviral integration site 3	0.506
Zfp36	zinc finger protein 36	0.479
Akr1c6	aldo-keto reductase family 1, member C6	0.451
Pim1	proviral integration site 1	0.413	Mouse
Sva	seminal vesicle antigen	0.380
Sult3a1	sulfotransferase family 3A, member 1	0.296
Cyp2c50	cytochrome P450, family 2, subfamily c, polypeptide 50	0.281
F9	coagulation factor IX	0.237
Cfhr2	complement factor H-related 2	0.237
Cfd	complement factor D (adipsin)	0.236
Mup6	major urinary protein 6	0.216	Mouse
4930579C15Rik	RIKEN cDNA 4930579C15 gene	0.205
Cyp3a11	cytochrome P450, family 3, subfamily a, polypeptide 11	0.183
Tdo2	tryptophan 2,3-dioxygenase	0.159
Klk1b4	kallikrein 1-related pepidase b4	0.157
Ces3a	carboxylesterase 3A	0.138
Otc	ornithine transcarbamylase	0.130
Art1	ADP-ribosyltransferase 1	0.122
Prl2b1	prolactin family 2, subfamily b, member 1	0.122
Mug2	murinoglobulin 2	0.114
Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	0.104
Crp	C-reactive protein, pentraxin-related	0.103
Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	0.100
Cfhr1	complement factor H-related 1	0.097
Socs1	suppressor of cytokine signaling 1	0.096
Pbsn	probasin	0.096	Mouse
Vmn1r45	vomeronasal 1 receptor 45	0.096
Cps1	carbamoyl-phosphate synthetase 1	0.094
Slco1b2	solute carrier organic anion transporter family, member 1b2	0.087
Tnni2	troponin I, skeletal, fast 2	0.087
Gm4788	predicted gene 4788	0.086
Orm2	orosomucoid 2	0.084
Cyp2d10	cytochrome P450, family 2, subfamily d, polypeptide 10	0.079
Mas1	MAS1 oncogene	0.078
Klk1b26	kallikrein 1-related petidase b26	0.075
Cidec	cell death-inducing DFFA-like effector c	0.075
Tnfsf4	tumor necrosis factor (ligand) superfamily, member 4	0.074
Klk1b11	kallikrein 1-related peptidase b11	0.074
Il5	interleukin 5	0.073
Cyp3a16	cytochrome P450, family 3, subfamily a, polypeptide 16	0.071
Sh3bgrl3	SH3 domain binding glutamic acid-rich protein-like 3	0.071
Gm14743	predicted gene 14743	0.070	Mouse
Csn2	casein beta	0.069
Ces1c	carboxylesterase 1C	0.069
Cd70	CD70 antigen	0.068
Ang2	angiogenin, ribonuclease A family, member 2	0.067
Gzmn	granzyme N	0.063
U46068	cDNA sequence U46068	0.062
Anxa10	annexin A10	0.061
Hephl1	hephaestin-like 1	0.060
F13b	coagulation factor XIII, beta subunit	0.060
Sult1d1	sulfotransferase family 1D, member 1	0.059
Pnpla2	patatin-like phospholipase domain containing 2	0.058
5430402E10Rik	RIKEN cDNA 5430402E10 gene	0.057	Mouse
Adig	adipogenin	0.057
Car6	carbonic anhydrase 6	0.056
Scn9a	sodium channel, voltage-gated, type IX, alpha	0.055
Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	0.054
Tph1	tryptophan hydroxylase 1	0.053
Klra7	killer cell lectin-like receptor, subfamily A, member 7	0.052
Btg2	B-cell translocation gene 2, anti-proliferative	0.048
Efhd2	EF hand domain containing 2	0.047
Omt2b	oocyte maturation, beta	0.047
Mucl1	mucin-like 1	0.045
Mpz	myelin protein zero	0.042
Cacna1s	calcium channel, voltage-dependent, L type, alpha 1S subunit	0.041
Grpr	gastrin releasing peptide receptor	0.041
Ngf	nerve growth factor	0.040
Tnp1	transition protein 1	0.040
Fga	fibrinogen alpha chain	0.040
Ckm	creatine kinase, muscle	0.040
Slco6c1	solute carrier organic anion transporter family, member 6c1	0.039
Naa11	N(alpha)-acetyltransferase 11, NatA catalytic subunit	0.039
Cma1	chymase 1, mast cell	0.038
Adrb3	adrenergic receptor, beta 3	0.038
Saa4	serum amyloid A 4	0.037
BC024139	cDNA sequence BC024139	0.037
Smyd1	SET and MYND domain containing 1	0.035
Fabp1	fatty acid binding protein 1, liver	0.034
Cdh4	cadherin 4	0.034
Klf9	Kruppel-like factor 9	0.034
Mup20	major urinary protein 20	0.034	Mouse
C730048C13Rik	RIKEN cDNA C730048C13 gene	0.034
Cyp2c29	cytochrome P450, family 2, subfamily c, polypeptide 29	0.034
Ces1d	carboxylesterase 1D	0.033
Sult1b1	sulfotransferase family 1B, member 1	0.033
Olfr813	olfactory receptor 813	0.033
Pgk2	phosphoglycerate kinase 2	0.033
Gngt1	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	0.033
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.032
Vmn1r119	vomeronasal 1 receptor 119	0.032
Uox	urate oxidase	0.032
Oas1h	2'-5' oligoadenylate synthetase 1H	0.031
Pdc	phosducin	0.031
Cyp2f2	cytochrome P450, family 2, subfamily f, polypeptide 2	0.030
Prl7a2	prolactin family 7, subfamily a, member 2	0.029
Cyp2c37	cytochrome P450, family 2. subfamily c, polypeptide 37	0.028
Olfr701	olfactory receptor 701	0.028
Klra4	killer cell lectin-like receptor, subfamily A, member 4	0.028
Gzmg	granzyme G	0.028
Ucp3	uncoupling protein 3 (mitochondrial, proton carrier)	0.027
Capn1	calpain 1	0.027
Olfr1170	olfactory receptor 1170	0.027
Vmn2r88	vomeronasal 2, receptor 88	0.027
Btn1a1	butyrophilin, subfamily 1, member A1	0.027
4922505E12Rik	RIKEN cDNA 4922505E12 gene	0.027
Slc7a5	solute carrier family 7 (cationic amino acid transporter, y+ system), member 5	0.026
Dnajc24	DnaJ (Hsp40) homolog, subfamily C, member 24	0.026
Prp2	proline rich protein 2	0.026
Mbl1	mannose-binding lectin (protein A) 1	0.026
Pon1	paraoxonase 1	0.026
Slc17a2	solute carrier family 17 (sodium phosphate), member 2	0.025
Gm6662	predicted gene 6662	0.025
Iapp	islet amyloid polypeptide	0.025
Hmx2	H6 homeobox 2	0.025
Gm5895	predicted gene 5895	0.025
Fndc1	fibronectin type III domain containing 1	0.025
Adipoq	adiponectin, C1Q and collagen domain containing	0.025
Mcpt4	mast cell protease 4	0.024
Ces1e	carboxylesterase 1E	0.024
Olfm1	olfactomedin 1	0.024
Olfr1176	olfactory receptor 1176	0.024
Mylk2	myosin, light polypeptide kinase 2, skeletal muscle	0.024
Vmn1r11	vomeronasal 1 receptor 11	0.024
Lcn13	lipocalin 13	0.024	Mouse
Myh1	myosin, heavy polypeptide 1, skeletal muscle, adult	0.024
Serpina6	serine (or cysteine) peptidase inhibitor, clade A, member 6	0.024
Npy5r	neuropeptide Y receptor Y5	0.024
Vmn1r51	vomeronasal 1 receptor 51	0.023
Lcn4	lipocalin 4	0.023	Mouse
Irs3	insulin receptor substrate 3	0.023
Ppp1r15a	protein phosphatase 1, regulatory (inhibitor) subunit 15A	0.023
Slco1a1	solute carrier organic anion transporter family, member 1a1	0.022
Vpreb1	pre-B lymphocyte gene 1	0.022
Baat	bile acid-Coenzyme A: amino acid N-acyltransferase	0.022
Pramel7	preferentially expressed antigen in melanoma like 7	0.022
Foxf2	forkhead box F2	0.021
P2ry2	purinergic receptor P2Y, G-protein coupled 2	0.021
Serpina1c	serine (or cysteine) peptidase inhibitor, clade A, member 1C	0.021
Cacna2d4	calcium channel, voltage-dependent, alpha 2/delta subunit 4	0.021
BC048679	cDNA sequence BC048679	0.021
Akr1c20	aldo-keto reductase family 1, member C20	0.021
Klk1b8	kallikrein 1-related peptidase b8	0.021
Fbxw24	F-box and WD-40 domain protein 24	0.021
Ryr2	ryanodine receptor 2, cardiac	0.020
Olfr620	olfactory receptor 620	0.020
Car5a	carbonic anhydrase 5a, mitochondrial	0.020
Vmn1r101	vomeronasal 1 receptor 101	0.020
Vmn1r149	vomeronasal 1 receptor 149	0.020
Vmn1r55	vomeronasal 1 receptor 55	0.020
Olfr1450	olfactory receptor 1450	0.020
Gm14744	predicted gene 14744	0.019	Mouse
Grik1	glutamate receptor, ionotropic, kainate 1	0.019
Cdhr3	cadherin-related family member 3	0.019
Hist1h2bb	histone cluster 1, H2bb	0.019
Tmprss11d	transmembrane protease, serine 11d	0.019
Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.019
Olfr344	olfactory receptor 344	0.019
Accn5	amiloride-sensitive cation channel 5, intestinal	0.019
Gltp	glycolipid transfer protein	0.019
Hao1	hydroxyacid oxidase 1, liver	0.019
Rhog	ras homolog gene family, member G	0.018
Gm12769	predicted gene 12769	0.018
Nadk	NAD kinase	0.018
Impdh1	inosine 5'-phosphate dehydrogenase 1	0.018
Znhit3	zinc finger, HIT type 3	0.018
Dlx1	distal-less homeobox 1	0.018
Lgals7	lectin, galactose binding, soluble 7	0.018
Serpinb3a	serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A	0.018
Kcnj2	potassium inwardly-rectifying channel, subfamily J, member 2	0.018
Kcnk3	potassium channel, subfamily K, member 3	0.018
Pdyn	prodynorphin	0.018
Maff	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)	0.018
Vmn1r179	vomeronasal 1 receptor 179	0.017
Tpbpb	trophoblast specific protein beta	0.017
Cyp3a25	cytochrome P450, family 3, subfamily a, polypeptide 25	0.017
Pip	prolactin induced protein	0.017
Hrg	histidine-rich glycoprotein	0.017
Cphx	cytoplasmic polyadenylated homeobox	0.017
Hpcal1	hippocalcin-like 1	0.017
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.017
Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1	0.017
Olfr372	olfactory receptor 372	0.017
Dcpp1	demilune cell and parotid protein 1	0.017
Necap2	NECAP endocytosis associated 2	0.017
Dcdc2c	doublecortin domain containing 2C	0.017
Olfr1219	olfactory receptor 1219	0.017
Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	0.016
Fgb	fibrinogen beta chain	0.016
Per1	period homolog 1 (Drosophila)	0.016
Cylc1	cylicin, basic protein of sperm head cytoskeleton 1	0.016
LOC100504348	hypothetical protein LOC100504348	0.016
Serpinb3d	serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3D	0.016
Gsdma2	gasdermin A2	0.016
Colec10	collectin sub-family member 10	0.016
Fgf20	fibroblast growth factor 20	0.016
Gm5326	predicted gene 5326	0.016
Defb12	defensin beta 12	0.016
Ibsp	integrin binding sialoprotein	0.016
Cd209f	CD209f antigen	0.016
Nrg3	neuregulin 3	0.016
Vmn2r104	vomeronasal 2, receptor 104	0.016
Serpina3c	serine (or cysteine) peptidase inhibitor, clade A, member 3C	0.016
Gm3763	predicted gene 3763	0.016
Morf4l2	mortality factor 4 like 2	0.016
Shkbp1	Sh3kbp1 binding protein 1	0.016
Prl7a1	prolactin family 7, subfamily a, member 1	0.016
Ctsll3	cathepsin L-like 3	0.016
Vmn1r57	vomeronasal 1 receptor 57	0.015
Olfr441	olfactory receptor 441	0.015
Krt36	keratin 36	0.015
Olfr1112	olfactory receptor 1112	0.015
Olfr832	olfactory receptor 832	0.015
1700074P13Rik	RIKEN cDNA 1700074P13 gene	0.015
4932429P05Rik	RIKEN cDNA 4932429P05 gene	0.015
BC048562	cDNA sequence BC048562	0.015
Olfr935	olfactory receptor 935	0.015
Olfr1212	olfactory receptor 1212	0.015
Cmah	cytidine monophospho-N-acetylneuraminic acid hydroxylase	0.015
Lce1m	late cornified envelope 1M	0.015
Klra8	killer cell lectin-like receptor, subfamily A, member 8	0.015
Sgca	sarcoglycan, alpha (dystrophin-associated glycoprotein)	0.015
Vmn1r59	vomeronasal 1 receptor 59	0.015
Cyp2a4	cytochrome P450, family 2, subfamily a, polypeptide 4	0.015
Gm7052	predicted gene 7052	0.015
Sval2	seminal vesicle antigen-like 2	0.015
Cma2	chymase 2, mast cell	0.014
Vmn1r185	vomeronasal 1 receptor 185	0.014
Calr3	calreticulin 3	0.014
Rag2	recombination activating gene 2	0.014
Klk1b1	kallikrein 1-related peptidase b1	0.014
Vmn2r61	vomeronasal 2, receptor 61	0.014
Gsdmc4	gasdermin C4	0.014
Ccdc7	coiled-coil domain containing 7	0.014
Hbb-b1	hemoglobin, beta adult major chain	0.014
Retn	resistin	0.014
Ifna6	interferon alpha 6	0.014
Olfr160	olfactory receptor 160	0.014
Gsta3	glutathione S-transferase, alpha 3	0.013
Chrna9	cholinergic receptor, nicotinic, alpha polypeptide 9	0.013
St6galnac1	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1	0.013
Omd	osteomodulin	0.013
Olfr1046	olfactory receptor 1046	0.013
Defa23	defensin, alpha, 23	0.013
Tnfaip1	tumor necrosis factor, alpha-induced protein 1 (endothelial)	0.013
Mrgprb1	MAS-related GPR, member B1	0.013
Olfr559	olfactory receptor 559	0.013
Cyp2c39	cytochrome P450, family 2, subfamily c, polypeptide 39	0.013
5430401F13Rik	RIKEN cDNA 5430401F13 gene	0.013
Olfr1218	olfactory receptor 1218	0.013
Inmt	indolethylamine N-methyltransferase	0.013
Thrsp	thyroid hormone responsive SPOT14 homolog (Rattus)	0.013
4930569F06Rik	RIKEN cDNA 4930569F06 gene	0.013
Gm13088	predicted gene 13088	0.013
Scn10a	sodium channel, voltage-gated, type X, alpha	0.013
Svs2	seminal vesicle secretory protein 2	0.013
Gzmd	granzyme D	0.013
Pfdn1	prefoldin 1	0.013
Prl3b1	prolactin family 3, subfamily b, member 1	0.013
Shank1	SH3/ankyrin domain gene 1	0.013
Olfr1329	olfactory receptor 1329	0.013
Spinkl	serine protease inhibitor, Kazal type-like	0.012
Olfr186	olfactory receptor 186	0.012
Gm5938	predicted gene 5938	0.012	Mouse
Junb	Jun-B oncogene	0.012
9430007A20Rik	RIKEN cDNA 9430007A20 gene	0.012
Olfr558	olfactory receptor 558	0.012
Ceacam12	carcinoembryonic antigen-related cell adhesion molecule 12	0.012
Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)	0.012
Zfp42	zinc finger protein 42	0.012
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.012
4931407G18Rik	RIKEN cDNA 4931407G18 gene	0.012
Klk1b22	kallikrein 1-related peptidase b22	0.012
Stxbp2	syntaxin binding protein 2	0.012
Gzmc	granzyme C	0.012
Mepe	matrix extracellular phosphoglycoprotein with ASARM motif (bone)	0.012
V1rd19	vomeronasal 1 receptor, D19	0.012
Olfr938	olfactory receptor 938	0.012
Klkb1	kallikrein B, plasma 1	0.012
Gm14374	predicted gene 14374	0.012
Olfr298	olfactory receptor 298	0.012
Rgs21	regulator of G-protein signalling 21	0.012
Vmn2r57	vomeronasal 2, receptor 57	0.012
Spt1	salivary protein 1	0.012
Gm7732	predicted gene 7732	0.012
Actg1	actin, gamma, cytoplasmic 1	0.012
Gm10228	predicted gene 10228	0.012
Ifng	interferon gamma	0.012
Capzb	capping protein (actin filament) muscle Z-line, beta	0.012
Vmn1r228	vomeronasal 1 receptor 228	0.012
Olfr1189	olfactory receptor 1189	0.011
Gm7736	predicted gene 7736	0.011
Sept14	septin 14	0.011
Calm1	calmodulin 1	0.011
Olfr1446	olfactory receptor 1446	0.011
Cyp2d12	cytochrome P450, family 2, subfamily d, polypeptide 12	0.011
Asb15	ankyrin repeat and SOCS box-containing 15	0.011
Dmrt3	doublesex and mab-3 related transcription factor 3	0.011
Hyal4	hyaluronoglucosaminidase 4	0.011
Olfr1507	olfactory receptor 1507	0.011
Tas2r140	taste receptor, type 2, member 140	0.011
Olfr143	olfactory receptor 143	0.011
5430430K15Rik	RIKEN cDNA 5430430K15 gene	0.011
Gm13119	predicted gene 13119	0.011
Prl3d3	prolactin family 3, subfamily d, member 3	0.011
Csn1s2b	casein alpha s2-like B	0.011
Oit1	oncoprotein induced transcript 1	0.011
Slc28a2	solute carrier family 28 (sodium-coupled nucleoside transporter), member 2	0.011
Olfr724	olfactory receptor 724	0.011
Olfr1034	olfactory receptor 1034	0.011
Mug1	murinoglobulin 1	0.011
Olfr1197	olfactory receptor 1197	0.011
Ifnb1	interferon beta 1, fibroblast	0.011
Angptl4	angiopoietin-like 4	0.011
Armcx2	armadillo repeat containing, X-linked 2	0.011
Olfr1164	olfactory receptor 1164	0.011
Defb26	defensin beta 26	0.011
Olfr138	olfactory receptor 138	0.010
Olfr1166	olfactory receptor 1166	0.010
Gnb1	guanine nucleotide binding protein (G protein), beta 1	0.010
Serpina1a	serine (or cysteine) peptidase inhibitor, clade A, member 1A	0.010
Cyp4f17	cytochrome P450, family 4, subfamily f, polypeptide 17	0.010
Acsm3	acyl-CoA synthetase medium-chain family member 3	0.010
Car3	carbonic anhydrase 3	0.010
Rpl3l	ribosomal protein L3-like	0.010
B3galt2	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2	0.010
Gm10384	predicted gene 10384	0.010
3110018I06Rik	RIKEN cDNA 3110018I06 gene	0.010
Tnmd	tenomodulin	0.010
Zfy1	zinc finger protein 1, Y linked	0.010
Klra1	killer cell lectin-like receptor, subfamily A, member 1	0.010
Pate-e	prostate and testis expressed E	0.010
Crisp3	cysteine-rich secretory protein 3	0.010
Zyx	zyxin	0.010
Myh4	myosin, heavy polypeptide 4, skeletal muscle	0.010
Mrgprb2	MAS-related GPR, member B2	0.010