IMP: Integrative Multi-species Prediction

Mus musculus

14 genes annotated in mouse

regulation of neutrophil chemotaxis

Any process that modulates the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of neutrophil chemotaxis"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "regulation of neutrophil chemotaxis" (in gray)

Name	Description	Probability	Func Analog Organism
Ccl2	chemokine (C-C motif) ligand 2	0.987
Cd44	CD44 antigen	0.967
Ccr1	chemokine (C-C motif) receptor 1	0.966	Mouse
Selp	selectin, platelet	0.962
Ccr2	chemokine (C-C motif) receptor 2	0.959	Mouse
Il1b	interleukin 1 beta	0.813
Ccl3	chemokine (C-C motif) ligand 3	0.788	Mouse
Lyz2	lysozyme 2	0.729
Itgax	integrin alpha X	0.716
Ccl8	chemokine (C-C motif) ligand 8	0.535
Pak1	p21 protein (Cdc42/Rac)-activated kinase 1	0.506
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.492
Cxcl13	chemokine (C-X-C motif) ligand 13	0.492
H2-Aa	histocompatibility 2, class II antigen A, alpha	0.471
Ltb	lymphotoxin B	0.451
C3ar1	complement component 3a receptor 1	0.437
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.436
Fcgr1	Fc receptor, IgG, high affinity I	0.434
Il2rb	interleukin 2 receptor, beta chain	0.418
Itgb2	integrin beta 2	0.409
H2-Eb1	histocompatibility 2, class II antigen E beta	0.394
Icam1	intercellular adhesion molecule 1	0.306
Batf	basic leucine zipper transcription factor, ATF-like	0.300
AF251705	cDNA sequence AF251705	0.299
Ctsw	cathepsin W	0.296
Cxcr2	chemokine (C-X-C motif) receptor 2	0.291	Mouse Rat
Ccl7	chemokine (C-C motif) ligand 7	0.279	Mouse
Il1r1	interleukin 1 receptor, type I	0.274
Ccl9	chemokine (C-C motif) ligand 9	0.244	Mouse
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.243
Tnf	tumor necrosis factor	0.240
Il10ra	interleukin 10 receptor, alpha	0.232
Ccl12	chemokine (C-C motif) ligand 12	0.232	Mouse
Sfpi1	SFFV proviral integration 1	0.217
Hp	haptoglobin	0.214
Cx3cr1	chemokine (C-X3-C) receptor 1	0.205	Mouse
Ccl4	chemokine (C-C motif) ligand 4	0.204	Mouse
Gzma	granzyme A	0.196
Chi3l3	chitinase 3-like 3	0.188
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.185
Ifng	interferon gamma	0.181
Il1rn	interleukin 1 receptor antagonist	0.180
Mmp8	matrix metallopeptidase 8	0.171
Mmp12	matrix metallopeptidase 12	0.168
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.164
Ccl6	chemokine (C-C motif) ligand 6	0.164	Mouse
Cd7	CD7 antigen	0.162
Sele	selectin, endothelial cell	0.157
Lin7c	lin-7 homolog C (C. elegans)	0.157
Msr1	macrophage scavenger receptor 1	0.155
Cybb	cytochrome b-245, beta polypeptide	0.149
Slfn1	schlafen 1	0.143
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.142
Folr2	folate receptor 2 (fetal)	0.141
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.138
Itgal	integrin alpha L	0.138
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.137
Lta	lymphotoxin A	0.121
Il1a	interleukin 1 alpha	0.120
Cxcl2	chemokine (C-X-C motif) ligand 2	0.115
H2-Ab1	histocompatibility 2, class II antigen A, beta 1	0.115
Ear2	eosinophil-associated, ribonuclease A family, member 2	0.114
Bdkrb1	bradykinin receptor, beta 1	0.109
Cd3e	CD3 antigen, epsilon polypeptide	0.109
Ifitm6	interferon induced transmembrane protein 6	0.102
Csf1	colony stimulating factor 1 (macrophage)	0.102
Mmp9	matrix metallopeptidase 9	0.099
Ciita	class II transactivator	0.099
Ch25h	cholesterol 25-hydroxylase	0.097
Ubd	ubiquitin D	0.097
Cd14	CD14 antigen	0.097
Selplg	selectin, platelet (p-selectin) ligand	0.096
Xcr1	chemokine (C motif) receptor 1	0.096	Mouse
Casp1	caspase 1	0.095
Sh2d2a	SH2 domain protein 2A	0.093
Myo1f	myosin IF	0.091
Tlr4	toll-like receptor 4	0.091
Slit3	slit homolog 3 (Drosophila)	0.090
Gzmb	granzyme B	0.085
Rac1	RAS-related C3 botulinum substrate 1	0.085
Stat5a	signal transducer and activator of transcription 5A	0.084
Fpr3	formyl peptide receptor 3	0.083	Mouse
Cd96	CD96 antigen	0.081
Gm14548	predicted gene 14548	0.081
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.080
C3	complement component 3	0.080
Cxcr3	chemokine (C-X-C motif) receptor 3	0.080	Mouse
Fas	Fas (TNF receptor superfamily member 6)	0.078
Tlr2	toll-like receptor 2	0.077
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.077
Robo1	roundabout homolog 1 (Drosophila)	0.076
S100a8	S100 calcium binding protein A8 (calgranulin A)	0.071
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.071
Cxcl1	chemokine (C-X-C motif) ligand 1	0.071
Il18r1	interleukin 18 receptor 1	0.071
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.070
Cd2	CD2 antigen	0.069
Ly9	lymphocyte antigen 9	0.067
Ifngr1	interferon gamma receptor 1	0.065
Ccl5	chemokine (C-C motif) ligand 5	0.064	Mouse
Lilrb3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.064
Nrp1	neuropilin 1	0.062
Gpr132	G protein-coupled receptor 132	0.061
Ikzf1	IKAROS family zinc finger 1	0.059
Clec4d	C-type lectin domain family 4, member d	0.059
Ccr5	chemokine (C-C motif) receptor 5	0.058	Mouse
Pik3ap1	phosphoinositide-3-kinase adaptor protein 1	0.058
Pdcd1	programmed cell death 1	0.055
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.055
Il18rap	interleukin 18 receptor accessory protein	0.055
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.055
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.053
Mmp3	matrix metallopeptidase 3	0.052
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.052
Foxp3	forkhead box P3	0.052
Irg1	immunoresponsive gene 1	0.051
Il27ra	interleukin 27 receptor, alpha	0.051
Ccr7	chemokine (C-C motif) receptor 7	0.049
Itgam	integrin alpha M	0.047
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.047
Slpi	secretory leukocyte peptidase inhibitor	0.047
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.046
Has1	hyaluronan synthase1	0.046
Osmr	oncostatin M receptor	0.045
Il12rb2	interleukin 12 receptor, beta 2	0.045
Gzmk	granzyme K	0.044
H2-DMa	histocompatibility 2, class II, locus DMa	0.043
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.043
Ccl11	chemokine (C-C motif) ligand 11	0.043	Mouse
Lrg1	leucine-rich alpha-2-glycoprotein 1	0.042
9430031J16Rik	RIKEN cDNA 9430031J16 gene	0.042
Icos	inducible T-cell co-stimulator	0.042
Cxcr4	chemokine (C-X-C motif) receptor 4	0.042	Zebrafish Mouse
Saa3	serum amyloid A 3	0.042
Klra5	killer cell lectin-like receptor, subfamily A, member 5	0.040
Slfn4	schlafen 4	0.040
Myd88	myeloid differentiation primary response gene 88	0.040
Prrx1	paired related homeobox 1	0.040
Meox1	mesenchyme homeobox 1	0.039
Ccl22	chemokine (C-C motif) ligand 22	0.039
S1pr4	sphingosine-1-phosphate receptor 4	0.039
Tbxas1	thromboxane A synthase 1, platelet	0.039
S100a9	S100 calcium binding protein A9 (calgranulin B)	0.038
Cxcl9	chemokine (C-X-C motif) ligand 9	0.038
Cd5	CD5 antigen	0.037
C5ar1	complement component 5a receptor 1	0.037
Jak3	Janus kinase 3	0.037
Lcn2	lipocalin 2	0.036
Clec4n	C-type lectin domain family 4, member n	0.036
Ncr1	natural cytotoxicity triggering receptor 1	0.035
Cd3g	CD3 antigen, gamma polypeptide	0.035
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.035
Ptgir	prostaglandin I receptor (IP)	0.034
Cd3d	CD3 antigen, delta polypeptide	0.034
Expi	extracellular proteinase inhibitor	0.034
Cd209b	CD209b antigen	0.033
Nkg7	natural killer cell group 7 sequence	0.032
Ccr6	chemokine (C-C motif) receptor 6	0.032	Mouse
Flt3	FMS-like tyrosine kinase 3	0.032
Ooep	oocyte expressed protein homolog (dog)	0.031
Robo2	roundabout homolog 2 (Drosophila)	0.031
Lsp1	lymphocyte specific 1	0.031
Cd40	CD40 antigen	0.031
Cd300ld	CD300 molecule-like family member d	0.031
Lst1	leukocyte specific transcript 1	0.031
Prkar1b	protein kinase, cAMP dependent regulatory, type I beta	0.030
Bcl3	B-cell leukemia/lymphoma 3	0.030
Plxnd1	plexin D1	0.029
Itk	IL2-inducible T-cell kinase	0.029
Atp6v1a	ATPase, H+ transporting, lysosomal V1 subunit A	0.029
Fasl	Fas ligand (TNF superfamily, member 6)	0.028
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.028
Cd180	CD180 antigen	0.028
Vax2	ventral anterior homeobox containing gene 2	0.028
Dlg1	discs, large homolog 1 (Drosophila)	0.027
Prg3	proteoglycan 3	0.027
Il7r	interleukin 7 receptor	0.027
Niacr1	niacin receptor 1	0.027
Ccr1l1	chemokine (C-C motif) receptor 1-like 1	0.027	Mouse
Acvr1	activin A receptor, type 1	0.026
Elk4	ELK4, member of ETS oncogene family	0.026
Socs1	suppressor of cytokine signaling 1	0.026
Laptm5	lysosomal-associated protein transmembrane 5	0.026
Mrpl3	mitochondrial ribosomal protein L3	0.025
Sftpd	surfactant associated protein D	0.025
Tnfsf8	tumor necrosis factor (ligand) superfamily, member 8	0.025
Arhgdib	Rho, GDP dissociation inhibitor (GDI) beta	0.025
Il1f9	interleukin 1 family, member 9	0.025
Steap4	STEAP family member 4	0.025
Fcer2a	Fc receptor, IgE, low affinity II, alpha polypeptide	0.024
Cxcl5	chemokine (C-X-C motif) ligand 5	0.023
Cd52	CD52 antigen	0.023
F10	coagulation factor X	0.023
Siglece	sialic acid binding Ig-like lectin E	0.023
Ccl20	chemokine (C-C motif) ligand 20	0.023
Apoe	apolipoprotein E	0.023
Ttc7	tetratricopeptide repeat domain 7	0.022
Cd33	CD33 antigen	0.022
Efnb2	ephrin B2	0.022
C1qc	complement component 1, q subcomponent, C chain	0.022
Slc22a17	solute carrier family 22 (organic cation transporter), member 17	0.022
Arhgap1	Rho GTPase activating protein 1	0.022
Ngp	neutrophilic granule protein	0.022
Ncf4	neutrophil cytosolic factor 4	0.022
Prdm1	PR domain containing 1, with ZNF domain	0.021
Cd6	CD6 antigen	0.021
Aire	autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)	0.021
Olfr1264	olfactory receptor 1264	0.021
Pdcd1lg2	programmed cell death 1 ligand 2	0.021
Tlr8	toll-like receptor 8	0.020
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.020
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.020
Gfpt2	glutamine fructose-6-phosphate transaminase 2	0.020
Reg3g	regenerating islet-derived 3 gamma	0.020
Serping1	serine (or cysteine) peptidase inhibitor, clade G, member 1	0.020
Il7	interleukin 7	0.020
Pik3cb	phosphatidylinositol 3-kinase, catalytic, beta polypeptide	0.020
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.019
Tlr7	toll-like receptor 7	0.019
Mrc1	mannose receptor, C type 1	0.019
Ccl17	chemokine (C-C motif) ligand 17	0.019	Mouse
Ncf1	neutrophil cytosolic factor 1	0.019
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.019
Ednrb	endothelin receptor type B	0.019
Clec4a2	C-type lectin domain family 4, member a2	0.018
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.018
Retnla	resistin like alpha	0.018
Sell	selectin, lymphocyte	0.018	Rat
Ccr9	chemokine (C-C motif) receptor 9	0.018	Mouse
Pglyrp1	peptidoglycan recognition protein 1	0.018
Rnd3	Rho family GTPase 3	0.018
Apod	apolipoprotein D	0.018
A4galt	alpha 1,4-galactosyltransferase	0.018
Havcr2	hepatitis A virus cellular receptor 2	0.018
Sfrp4	secreted frizzled-related protein 4	0.018
Smok3a	sperm motility kinase 3A	0.018
LOC100503923	hypothetical protein LOC100503923	0.018
Xcl1	chemokine (C motif) ligand 1	0.018
Il1rl1	interleukin 1 receptor-like 1	0.017
Mmp7	matrix metallopeptidase 7	0.017
Sln	sarcolipin	0.017
Aoah	acyloxyacyl hydrolase	0.017
Il12b	interleukin 12b	0.017
Il6	interleukin 6	0.017
Cd37	CD37 antigen	0.017
Elane	elastase, neutrophil expressed	0.017
AW112010	expressed sequence AW112010	0.017
Rhoa	ras homolog gene family, member A	0.017
Dcn	decorin	0.017
Itgb3	integrin beta 3	0.017
Dok2	docking protein 2	0.016
Rock2	Rho-associated coiled-coil containing protein kinase 2	0.016
Cd86	CD86 antigen	0.016
Smurf2	SMAD specific E3 ubiquitin protein ligase 2	0.016
Fpr-rs3	formyl peptide receptor, related sequence 3	0.016	Mouse
Cd8a	CD8 antigen, alpha chain	0.016
Cd209a	CD209a antigen	0.016
1100001G20Rik	RIKEN cDNA 1100001G20 gene	0.016
Ctnnb1	catenin (cadherin associated protein), beta 1	0.016
Dock2	dedicator of cyto-kinesis 2	0.015
Ly6d	lymphocyte antigen 6 complex, locus D	0.015
Opn1sw	opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)	0.015
Ltf	lactotransferrin	0.015
Dmbt1	deleted in malignant brain tumors 1	0.015
Cd8b1	CD8 antigen, beta chain 1	0.015
Tubb4	tubulin, beta 4	0.015
Lepr	leptin receptor	0.015
Mkl2	MKL/myocardin-like 2	0.015
Chi3l1	chitinase 3-like 1	0.015
Clec7a	C-type lectin domain family 7, member a	0.015
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.015
Timm10	translocase of inner mitochondrial membrane 10 homolog (yeast)	0.015
Gpr182	G protein-coupled receptor 182	0.014
Fcamr	Fc receptor, IgA, IgM, high affinity	0.014
Pycard	PYD and CARD domain containing	0.014
Cytip	cytohesin 1 interacting protein	0.014
Dnase1l3	deoxyribonuclease 1-like 3	0.014
Sdc3	syndecan 3	0.014
Arl10	ADP-ribosylation factor-like 10	0.014
Mfap2	microfibrillar-associated protein 2	0.014
Dock1	dedicator of cytokinesis 1	0.014
C1qb	complement component 1, q subcomponent, beta polypeptide	0.014
Il12a	interleukin 12a	0.014
Spink4	serine peptidase inhibitor, Kazal type 4	0.014
Cltc	clathrin, heavy polypeptide (Hc)	0.014
Gpr97	G protein-coupled receptor 97	0.014
Fpr2	formyl peptide receptor 2	0.014	Mouse
Zfp92	zinc finger protein 92	0.014
Nos2	nitric oxide synthase 2, inducible	0.013
Pcdh12	protocadherin 12	0.013
Foxi3	forkhead box I3	0.013
Ece1	endothelin converting enzyme 1	0.013
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.013
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.013
Klrc1	killer cell lectin-like receptor subfamily C, member 1	0.013
St3gal1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	0.013
Rac2	RAS-related C3 botulinum substrate 2	0.013
Cxcr5	chemokine (C-X-C motif) receptor 5	0.013	Mouse
Fpr1	formyl peptide receptor 1	0.013	Mouse
Gpr33	G protein-coupled receptor 33	0.013	Mouse
Sash3	SAM and SH3 domain containing 3	0.013
Atad3a	ATPase family, AAA domain containing 3A	0.013
Irf5	interferon regulatory factor 5	0.013
Hdc	histidine decarboxylase	0.013
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.013
Slamf8	SLAM family member 8	0.013
Capza2	capping protein (actin filament) muscle Z-line, alpha 2	0.012
Tbx21	T-box 21	0.012
Cd209e	CD209e antigen	0.012
Cpd	carboxypeptidase D	0.012
Retnlb	resistin like beta	0.012
Olfr70	olfactory receptor 70	0.012
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.012
Ly6c2	lymphocyte antigen 6 complex, locus C2	0.012
Cfh	complement component factor h	0.012
Slc9a3r1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.012
Aif1	allograft inflammatory factor 1	0.012
Mmp13	matrix metallopeptidase 13	0.012
Gm11428	predicted gene 11428	0.012
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.012
Necap2	NECAP endocytosis associated 2	0.012
Rgs9	regulator of G-protein signaling 9	0.012
Irf4	interferon regulatory factor 4	0.012
Spp1	secreted phosphoprotein 1	0.011
Camk1g	calcium/calmodulin-dependent protein kinase I gamma	0.011	Mouse
Fcrla	Fc receptor-like A	0.011
2410004A20Rik	RIKEN cDNA 2410004A20 gene	0.011
Serpinb9b	serine (or cysteine) peptidase inhibitor, clade B, member 9b	0.011
Plbd1	phospholipase B domain containing 1	0.011
Sytl3	synaptotagmin-like 3	0.011
Alox5ap	arachidonate 5-lipoxygenase activating protein	0.011
Fut2	fucosyltransferase 2	0.011
Chrne	cholinergic receptor, nicotinic, epsilon polypeptide	0.011
Acpp	acid phosphatase, prostate	0.011
Lag3	lymphocyte-activation gene 3	0.011
Arhgap9	Rho GTPase activating protein 9	0.011
Ggt5	gamma-glutamyltransferase 5	0.011
Cldn5	claudin 5	0.011
Fcgr3	Fc receptor, IgG, low affinity III	0.011
Lyve1	lymphatic vessel endothelial hyaluronan receptor 1	0.011
Psg17	pregnancy specific glycoprotein 17	0.011
Cd97	CD97 antigen	0.011
Inhbe	inhibin beta E	0.011
Tcl1b1	T-cell leukemia/lymphoma 1B, 1	0.011
Rtn2	reticulon 2 (Z-band associated protein)	0.011
Adcy8	adenylate cyclase 8	0.011
4932438H23Rik	RIKEN cDNA 4932438H23 gene	0.011
Cd160	CD160 antigen	0.011
Plau	plasminogen activator, urokinase	0.011
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.011
Pea15a	phosphoprotein enriched in astrocytes 15A	0.011
Gbp1	guanylate binding protein 1	0.011
Ppfia2	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2	0.011
Asprv1	aspartic peptidase, retroviral-like 1	0.011
Bst1	bone marrow stromal cell antigen 1	0.011
Ccr3	chemokine (C-C motif) receptor 3	0.010	Mouse
Mrgpra3	MAS-related GPR, member A3	0.010
Itgb7	integrin beta 7	0.010
H2-Ob	histocompatibility 2, O region beta locus	0.010
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.010
Socs3	suppressor of cytokine signaling 3	0.010
Gja10	gap junction protein, alpha 10	0.010
Hgf	hepatocyte growth factor	0.010
Tnfaip2	tumor necrosis factor, alpha-induced protein 2	0.010
Hmha1	histocompatibility (minor) HA-1	0.010
Ms4a8a	membrane-spanning 4-domains, subfamily A, member 8A	0.010