IMP
Process View
natural killer cell degranulation
The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a natural killer cell.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "natural killer cell degranulation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Rab27a | RAB27A, member RAS oncogene family | 1.000 | ||
| Prf1 | perforin 1 (pore forming protein) | 0.966 | ||
| Ap3b1 | adaptor-related protein complex 3, beta 1 subunit | 0.926 | ||
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.916 | ||
| Lyst | lysosomal trafficking regulator | 0.907 | ||
| Sytl5 | synaptotagmin-like 5 | 0.871 | ||
| Ctsb | cathepsin B | 0.712 | ||
| Plbd2 | phospholipase B domain containing 2 | 0.704 | ||
| Ctsd | cathepsin D | 0.516 | ||
| Stat1 | signal transducer and activator of transcription 1 | 0.463 | ||
| Mlph | melanophilin | 0.406 | ||
| Hps5 | Hermansky-Pudlak syndrome 5 homolog (human) | 0.329 | ||
| Stx11 | syntaxin 11 | 0.245 | ||
| Grn | granulin | 0.226 | ||
| Rab27b | RAB27b, member RAS oncogene family | 0.214 | Mouse | |
| Hexa | hexosaminidase A | 0.137 | ||
| Hps1 | Hermansky-Pudlak syndrome 1 homolog (human) | 0.129 | ||
| Pldn | pallidin | 0.082 | ||
| Hps6 | Hermansky-Pudlak syndrome 6 | 0.069 | ||
| Lamp2 | lysosomal-associated membrane protein 2 | 0.066 | ||
| Mfsd1 | major facilitator superfamily domain containing 1 | 0.049 | ||
| Hexb | hexosaminidase B | 0.048 | ||
| Rragc | Ras-related GTP binding C | 0.039 | ||
| Npc2 | Niemann Pick type C2 | 0.035 | ||
| Gns | glucosamine (N-acetyl)-6-sulfatase | 0.030 | ||
| Gabarap | gamma-aminobutyric acid receptor associated protein | 0.023 | ||
| Ikbkg | inhibitor of kappaB kinase gamma | 0.023 | ||
| Tcn2 | transcobalamin 2 | 0.022 | ||
| Atp6v0c | ATPase, H+ transporting, lysosomal V0 subunit C | 0.022 | ||
| Tpp1 | tripeptidyl peptidase I | 0.021 | ||
| 0610031J06Rik | RIKEN cDNA 0610031J06 gene | 0.020 | ||
| Lrp10 | low-density lipoprotein receptor-related protein 10 | 0.019 | ||
| Sytl1 | synaptotagmin-like 1 | 0.018 | ||
| Fth1 | ferritin heavy chain 1 | 0.018 | ||
| Igf2r | insulin-like growth factor 2 receptor | 0.018 | ||
| Ripk1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.017 | ||
| Ap1m1 | adaptor-related protein complex AP-1, mu subunit 1 | 0.017 | ||
| Akr1a4 | aldo-keto reductase family 1, member A4 (aldehyde reductase) | 0.017 | ||
| Psap | prosaposin | 0.017 | ||
| Nucb1 | nucleobindin 1 | 0.015 | ||
| Tmbim6 | transmembrane BAX inhibitor motif containing 6 | 0.015 | ||
| Sat1 | spermidine/spermine N1-acetyl transferase 1 | 0.015 | ||
| Itm2b | integral membrane protein 2B | 0.014 | ||
| Inpp5d | inositol polyphosphate-5-phosphatase D | 0.013 | ||
| Kdelr1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.013 | ||
| a | nonagouti | 0.013 | ||
| 2400001E08Rik | RIKEN cDNA 2400001E08 gene | 0.013 | ||
| Esrp1 | epithelial splicing regulatory protein 1 | 0.012 | ||
| Sumf1 | sulfatase modifying factor 1 | 0.012 | ||
| Arrdc1 | arrestin domain containing 1 | 0.012 | ||
| Ftl1 | ferritin light chain 1 | 0.012 | ||
| Tlr4 | toll-like receptor 4 | 0.011 | ||
| Sytl3 | synaptotagmin-like 3 | 0.011 | ||
| Pof1b | premature ovarian failure 1B | 0.011 | ||
| Nlrp3 | NLR family, pyrin domain containing 3 | 0.011 | ||
| Ctsl | cathepsin L | 0.010 | ||
| Ap3d1 | adaptor-related protein complex 3, delta 1 subunit | 0.010 | ||
| Pttg1ip | pituitary tumor-transforming 1 interacting protein | 0.010 | ||
| Rab38 | RAB38, member of RAS oncogene family | 0.010 |