Process View
A developmental process, independent of morphogenetic (shape) change, that is required for the central nervous system to attain its fully functional state. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "central nervous system maturation"
Name | Description | Probability | Func Analog Organism | |
---|---|---|---|---|
Grin2b | glutamate receptor, ionotropic, NMDA2B (epsilon 2) | 0.989 | ||
Gabrb3 | gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 | 0.619 | ||
Atp2b2 | ATPase, Ca++ transporting, plasma membrane 2 | 0.592 | ||
Cdk5r1 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 0.327 | ||
Ryr1 | ryanodine receptor 1, skeletal muscle | 0.294 | ||
Bsn | bassoon | 0.265 | ||
Kcnma1 | potassium large conductance calcium-activated channel, subfamily M, alpha member 1 | 0.247 | ||
Cplx1 | complexin 1 | 0.190 | ||
Drd2 | dopamine receptor D2 | 0.173 | ||
Cdk5r2 | cyclin-dependent kinase 5, regulatory subunit 2 (p39) | 0.134 | ||
Grin1 | glutamate receptor, ionotropic, NMDA1 (zeta 1) | 0.121 | ||
Actl6b | actin-like 6B | 0.119 | ||
Cckbr | cholecystokinin B receptor | 0.107 | ||
Scn8a | sodium channel, voltage-gated, type VIII, alpha | 0.104 | ||
Odz2 | odd Oz/ten-m homolog 2 (Drosophila) | 0.087 | ||
Ntrk2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.086 | ||
Grin2a | glutamate receptor, ionotropic, NMDA2A (epsilon 1) | 0.082 | ||
Kcnj11 | potassium inwardly rectifying channel, subfamily J, member 11 | 0.077 | ||
Cacnb4 | calcium channel, voltage-dependent, beta 4 subunit | 0.076 | ||
Cnr1 | cannabinoid receptor 1 (brain) | 0.072 | ||
Smad2 | MAD homolog 2 (Drosophila) | 0.071 | ||
Stx1a | syntaxin 1A (brain) | 0.070 | ||
Grid2 | glutamate receptor, ionotropic, delta 2 | 0.067 | ||
Drd1a | dopamine receptor D1A | 0.058 | ||
Gria4 | glutamate receptor, ionotropic, AMPA4 (alpha 4) | 0.056 | ||
Dynlt1b | dynein light chain Tctex-type 1D | 0.054 | ||
Dlg4 | discs, large homolog 4 (Drosophila) | 0.053 | ||
Kif5a | kinesin family member 5A | 0.052 | ||
Stx1b | syntaxin 1B | 0.051 | ||
Sarm1 | sterile alpha and HEAT/Armadillo motif containing 1 | 0.050 | ||
Cacnb2 | calcium channel, voltage-dependent, beta 2 subunit | 0.049 | ||
Uncx | UNC homeobox | 0.046 | ||
Htr1f | 5-hydroxytryptamine (serotonin) receptor 1F | 0.043 | ||
Elavl3 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) | 0.041 | ||
Ppef2 | protein phosphatase, EF hand calcium-binding domain 2 | 0.040 | ||
Sstr3 | somatostatin receptor 3 | 0.040 | ||
Neurod2 | neurogenic differentiation 2 | 0.040 | ||
Copb1 | coatomer protein complex, subunit beta 1 | 0.035 | ||
Kif5c | kinesin family member 5C | 0.034 | ||
Shbg | sex hormone binding globulin | 0.034 | ||
Col19a1 | collagen, type XIX, alpha 1 | 0.034 | ||
Elane | elastase, neutrophil expressed | 0.032 | ||
Chrnb2 | cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) | 0.031 | ||
Nos1 | nitric oxide synthase 1, neuronal | 0.031 | ||
Neurod1 | neurogenic differentiation 1 | 0.031 | ||
Six6 | sine oculis-related homeobox 6 homolog (Drosophila) | 0.031 | ||
Srcin1 | SRC kinase signaling inhibitor 1 | 0.028 | ||
Olfr690 | olfactory receptor 690 | 0.027 | ||
Astn1 | astrotactin 1 | 0.027 | ||
Myh6 | myosin, heavy polypeptide 6, cardiac muscle, alpha | 0.026 | ||
Lhx3 | LIM homeobox protein 3 | 0.026 | ||
Rtbdn | retbindin | 0.025 | ||
Rgs8 | regulator of G-protein signaling 8 | 0.025 | ||
Sspo | SCO-spondin | 0.024 | ||
Tecta | tectorin alpha | 0.024 | ||
Srrm3 | serine/arginine repetitive matrix 3 | 0.024 | ||
AI118078 | expressed sequence AI118078 | 0.023 | ||
Phox2b | paired-like homeobox 2b | 0.022 | ||
Ina | internexin neuronal intermediate filament protein, alpha | 0.022 | ||
Ssr3 | signal sequence receptor, gamma | 0.022 | ||
Tg | thyroglobulin | 0.022 | ||
Kcnj6 | potassium inwardly-rectifying channel, subfamily J, member 6 | 0.021 | ||
Bai1 | brain-specific angiogenesis inhibitor 1 | 0.021 | ||
Apc2 | adenomatosis polyposis coli 2 | 0.021 | ||
Slc18a3 | solute carrier family 18 (vesicular monoamine), member 3 | 0.020 | ||
Braf | Braf transforming gene | 0.020 | ||
Slc12a5 | solute carrier family 12, member 5 | 0.020 | ||
Pax8 | paired box gene 8 | 0.020 | ||
Hspa5 | heat shock protein 5 | 0.019 | ||
Chrna3 | cholinergic receptor, nicotinic, alpha polypeptide 3 | 0.019 | ||
Prkcc | protein kinase C, gamma | 0.019 | ||
Tars | threonyl-tRNA synthetase | 0.018 | ||
Grm1 | glutamate receptor, metabotropic 1 | 0.018 | ||
Kcnj3 | potassium inwardly-rectifying channel, subfamily J, member 3 | 0.018 | ||
Slc17a8 | solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8 | 0.018 | ||
Neurog2 | neurogenin 2 | 0.018 | ||
Il12rb1 | interleukin 12 receptor, beta 1 | 0.017 | ||
Slc22a6 | solute carrier family 22 (organic anion transporter), member 6 | 0.017 | ||
Hcn3 | hyperpolarization-activated, cyclic nucleotide-gated K+ 3 | 0.017 | ||
Tulp1 | tubby like protein 1 | 0.016 | ||
Axin2 | axin2 | 0.016 | ||
Il13 | interleukin 13 | 0.016 | ||
Mgat5b | mannoside acetylglucosaminyltransferase 5, isoenzyme B | 0.015 | ||
Chrna9 | cholinergic receptor, nicotinic, alpha polypeptide 9 | 0.015 | ||
Rnf112 | ring finger protein 112 | 0.015 | ||
Insm1 | insulinoma-associated 1 | 0.015 | ||
Kcna6 | potassium voltage-gated channel, shaker-related, subfamily, member 6 | 0.015 | ||
Klhl1 | kelch-like 1 (Drosophila) | 0.014 | ||
Agmat | agmatine ureohydrolase (agmatinase) | 0.014 | ||
Lhx5 | LIM homeobox protein 5 | 0.014 | ||
Magel2 | melanoma antigen, family L, 2 | 0.014 | ||
Sult4a1 | sulfotransferase family 4A, member 1 | 0.014 | ||
Rasgrf2 | RAS protein-specific guanine nucleotide-releasing factor 2 | 0.014 | ||
Alk | anaplastic lymphoma kinase | 0.013 | ||
Tac4 | tachykinin 4 | 0.013 | ||
Pcsk1n | proprotein convertase subtilisin/kexin type 1 inhibitor | 0.013 | ||
Serp1 | stress-associated endoplasmic reticulum protein 1 | 0.013 | ||
Pcsk2 | proprotein convertase subtilisin/kexin type 2 | 0.013 | ||
Kcnc3 | potassium voltage gated channel, Shaw-related subfamily, member 3 | 0.013 | ||
Epha8 | Eph receptor A8 | 0.013 | ||
Syt2 | synaptotagmin II | 0.013 | ||
Crxos1 | Crx opposite strand transcript 1 | 0.013 | ||
Srpk3 | serine/arginine-rich protein specific kinase 3 | 0.013 | ||
Crmp1 | collapsin response mediator protein 1 | 0.013 | ||
Cacng2 | calcium channel, voltage-dependent, gamma subunit 2 | 0.012 | ||
Atoh7 | atonal homolog 7 (Drosophila) | 0.012 | ||
Nsf | N-ethylmaleimide sensitive fusion protein | 0.012 | ||
Gad2 | glutamic acid decarboxylase 2 | 0.012 | ||
Hrh2 | histamine receptor H2 | 0.012 | ||
Gabrr2 | gamma-aminobutyric acid (GABA) C receptor, subunit rho 2 | 0.012 | ||
Ptpn5 | protein tyrosine phosphatase, non-receptor type 5 | 0.012 | ||
Cacna2d1 | calcium channel, voltage-dependent, alpha2/delta subunit 1 | 0.012 | ||
Dnase2b | deoxyribonuclease II beta | 0.012 | ||
Hpca | hippocalcin | 0.012 | ||
Otp | orthopedia homolog (Drosophila) | 0.012 | ||
Ncs1 | neuronal calcium sensor 1 | 0.011 | ||
Oprl1 | opioid receptor-like 1 | 0.011 | ||
Bex6 | brain expressed gene 6 | 0.011 | ||
Gabrd | gamma-aminobutyric acid (GABA) A receptor, subunit delta | 0.011 | ||
Pou3f1 | POU domain, class 3, transcription factor 1 | 0.011 | ||
Pcnxl2 | pecanex-like 2 (Drosophila) | 0.011 | ||
Ppfia4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.011 | ||
Cdh4 | cadherin 4 | 0.011 | ||
Chrna7 | cholinergic receptor, nicotinic, alpha polypeptide 7 | 0.011 | ||
En2 | engrailed 2 | 0.011 | ||
Capn9 | calpain 9 | 0.011 | ||
Fgf13 | fibroblast growth factor 13 | 0.010 | ||
Npas1 | neuronal PAS domain protein 1 | 0.010 | ||
Myt1 | myelin transcription factor 1 | 0.010 | ||
Dcc | deleted in colorectal carcinoma | 0.010 | ||
Tacr1 | tachykinin receptor 1 | 0.010 | ||
Msx3 | homeobox, msh-like 3 | 0.010 | ||
Htr5a | 5-hydroxytryptamine (serotonin) receptor 5A | 0.010 | ||
Kcnk3 | potassium channel, subfamily K, member 3 | 0.010 | ||
Pth2r | parathyroid hormone 2 receptor | 0.010 | ||
Ncan | neurocan | 0.010 |