IMP
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cellular response to oxygen radical
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion.
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Click on a gene's description to view its network relationships with genes known to be involved in "cellular response to oxygen radical"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Fbn1 | fibrillin 1 | 0.985 | ||
| Tgfbr2 | transforming growth factor, beta receptor II | 0.977 | ||
| Lox | lysyl oxidase | 0.959 | ||
| Apoe | apolipoprotein E | 0.923 | ||
| Eln | elastin | 0.702 | ||
| Atp7a | ATPase, Cu++ transporting, alpha polypeptide | 0.564 | ||
| Ldlr | low density lipoprotein receptor | 0.550 | ||
| Mmp2 | matrix metallopeptidase 2 | 0.437 | ||
| Tgfbr1 | transforming growth factor, beta receptor I | 0.386 | ||
| Smo | smoothened homolog (Drosophila) | 0.369 | ||
| Klf1 | Kruppel-like factor 1 (erythroid) | 0.277 | ||
| Agtr1a | angiotensin II receptor, type 1a | 0.237 | ||
| Slc31a1 | solute carrier family 31, member 1 | 0.198 | ||
| Steap3 | STEAP family member 3 | 0.153 | ||
| Efemp2 | epidermal growth factor-containing fibulin-like extracellular matrix protein 2 | 0.117 | Mouse | |
| Pdgfrb | platelet derived growth factor receptor, beta polypeptide | 0.099 | ||
| Hbb-b1 | hemoglobin, beta adult major chain | 0.092 | ||
| Mcl1 | myeloid cell leukemia sequence 1 | 0.091 | ||
| Gcsh | glycine cleavage system protein H (aminomethyl carrier) | 0.089 | ||
| Tgfb2 | transforming growth factor, beta 2 | 0.087 | ||
| Foxc1 | forkhead box C1 | 0.087 | ||
| Mt2 | metallothionein 2 | 0.083 | ||
| Idua | iduronidase, alpha-L- | 0.080 | ||
| Slc39a4 | solute carrier family 39 (zinc transporter), member 4 | 0.076 | ||
| Lamp2 | lysosomal-associated membrane protein 2 | 0.072 | ||
| E2f1 | E2F transcription factor 1 | 0.070 | ||
| Slc12a6 | solute carrier family 12, member 6 | 0.068 | ||
| Tenc1 | tensin like C1 domain-containing phosphatase | 0.067 | ||
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.067 | ||
| Ifngr1 | interferon gamma receptor 1 | 0.065 | ||
| Tmed10 | transmembrane emp24-like trafficking protein 10 (yeast) | 0.062 | ||
| Dbi | diazepam binding inhibitor | 0.062 | ||
| Lrp1 | low density lipoprotein receptor-related protein 1 | 0.062 | ||
| Sod3 | superoxide dismutase 3, extracellular | 0.060 | ||
| Romo1 | reactive oxygen species modulator 1 | 0.056 | ||
| Vegfa | vascular endothelial growth factor A | 0.055 | ||
| Tal1 | T-cell acute lymphocytic leukemia 1 | 0.053 | ||
| Prnp | prion protein | 0.053 | ||
| Duox2 | dual oxidase 2 | 0.052 | ||
| Cav1 | caveolin 1, caveolae protein | 0.052 | ||
| Tlr4 | toll-like receptor 4 | 0.048 | ||
| Agtr2 | angiotensin II receptor, type 2 | 0.048 | ||
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.044 | ||
| Fgfr1 | fibroblast growth factor receptor 1 | 0.040 | ||
| Ndufa9 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9 | 0.039 | ||
| Figf | c-fos induced growth factor | 0.039 | ||
| Camp | cathelicidin antimicrobial peptide | 0.039 | ||
| Rhd | Rh blood group, D antigen | 0.036 | ||
| Col6a1 | collagen, type VI, alpha 1 | 0.035 | ||
| Mrc2 | mannose receptor, C type 2 | 0.034 | ||
| Loxl1 | lysyl oxidase-like 1 | 0.033 | ||
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.033 | ||
| Col16a1 | collagen, type XVI, alpha 1 | 0.032 | ||
| Prelp | proline arginine-rich end leucine-rich repeat | 0.032 | ||
| Hint1 | histidine triad nucleotide binding protein 1 | 0.032 | ||
| Thbs2 | thrombospondin 2 | 0.032 | ||
| Hsd3b7 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | 0.032 | ||
| Spna1 | spectrin alpha 1 | 0.031 | ||
| Kat2a | K(lysine) acetyltransferase 2A | 0.030 | ||
| Smad1 | MAD homolog 1 (Drosophila) | 0.030 | ||
| Thbs3 | thrombospondin 3 | 0.030 | ||
| Ngp | neutrophilic granule protein | 0.030 | ||
| Gp1ba | glycoprotein 1b, alpha polypeptide | 0.030 | ||
| Ptrf | polymerase I and transcript release factor | 0.028 | ||
| Timp3 | tissue inhibitor of metalloproteinase 3 | 0.028 | ||
| Qdpr | quinoid dihydropteridine reductase | 0.027 | ||
| Tgfb1 | transforming growth factor, beta 1 | 0.027 | ||
| Epor | erythropoietin receptor | 0.027 | ||
| Thrb | thyroid hormone receptor beta | 0.027 | ||
| Hyal3 | hyaluronoglucosaminidase 3 | 0.026 | ||
| Nbl1 | neuroblastoma, suppression of tumorigenicity 1 | 0.026 | ||
| Adamts1 | a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 | 0.026 | ||
| Fam96a | family with sequence similarity 96, member A | 0.025 | ||
| Atp5a1 | ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1 | 0.025 | ||
| Fzd2 | frizzled homolog 2 (Drosophila) | 0.025 | ||
| Creg1 | cellular repressor of E1A-stimulated genes 1 | 0.024 | ||
| Aifm1 | apoptosis-inducing factor, mitochondrion-associated 1 | 0.024 | ||
| Cycs | cytochrome c, somatic | 0.024 | ||
| Mus81 | MUS81 endonuclease homolog (yeast) | 0.023 | ||
| Atp5b | ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit | 0.023 | ||
| Col1a2 | collagen, type I, alpha 2 | 0.023 | ||
| Car1 | carbonic anhydrase 1 | 0.023 | ||
| Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.023 | ||
| 2010106G01Rik | RIKEN cDNA 2010106G01 gene | 0.023 | ||
| Lamb2 | laminin, beta 2 | 0.022 | ||
| Sorbs3 | sorbin and SH3 domain containing 3 | 0.022 | ||
| Leprel2 | leprecan-like 2 | 0.022 | ||
| Mafk | v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian) | 0.022 | ||
| Scara3 | scavenger receptor class A, member 3 | 0.022 | ||
| Ednra | endothelin receptor type A | 0.022 | ||
| Abca1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.021 | ||
| Jag1 | jagged 1 | 0.021 | ||
| Sdhd | succinate dehydrogenase complex, subunit D, integral membrane protein | 0.021 | ||
| Cp | ceruloplasmin | 0.021 | ||
| Bcap31 | B-cell receptor-associated protein 31 | 0.020 | ||
| Hif1an | hypoxia-inducible factor 1, alpha subunit inhibitor | 0.020 | ||
| Lage3 | L antigen family, member 3 | 0.020 | ||
| Tgfb1i1 | transforming growth factor beta 1 induced transcript 1 | 0.020 | ||
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.020 | ||
| Cfh | complement component factor h | 0.020 | ||
| Svep1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 | 0.019 | ||
| Ep300 | E1A binding protein p300 | 0.019 | ||
| Adh5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 0.019 | ||
| Lass2 | LAG1 homolog, ceramide synthase 2 | 0.019 | ||
| Pkd1 | polycystic kidney disease 1 homolog | 0.019 | ||
| Aebp1 | AE binding protein 1 | 0.019 | ||
| Slc4a1 | solute carrier family 4 (anion exchanger), member 1 | 0.018 | ||
| Fam136a | family with sequence similarity 136, member A | 0.018 | ||
| Mrpl16 | mitochondrial ribosomal protein L16 | 0.018 | ||
| Elane | elastase, neutrophil expressed | 0.018 | ||
| Slc12a4 | solute carrier family 12, member 4 | 0.018 | ||
| Kit | kit oncogene | 0.018 | ||
| Cyb5 | cytochrome b-5 | 0.017 | ||
| Tmco1 | transmembrane and coiled-coil domains 1 | 0.017 | ||
| Btg1 | B-cell translocation gene 1, anti-proliferative | 0.017 | ||
| Agpat2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) | 0.017 | ||
| Slc40a1 | solute carrier family 40 (iron-regulated transporter), member 1 | 0.017 | ||
| Sp1 | trans-acting transcription factor 1 | 0.017 | ||
| Gja1 | gap junction protein, alpha 1 | 0.016 | ||
| Gypa | glycophorin A | 0.016 | ||
| Tnxb | tenascin XB | 0.016 | ||
| Tle2 | transducin-like enhancer of split 2, homolog of Drosophila E(spl) | 0.016 | ||
| Mmp11 | matrix metallopeptidase 11 | 0.016 | ||
| Casp3 | caspase 3 | 0.016 | ||
| Mrps17 | mitochondrial ribosomal protein S17 | 0.016 | ||
| Htra1 | HtrA serine peptidase 1 | 0.015 | ||
| Slit3 | slit homolog 3 (Drosophila) | 0.015 | ||
| Trp53 | transformation related protein 53 | 0.015 | ||
| Gata1 | GATA binding protein 1 | 0.015 | ||
| Wbp7 | WW domain binding protein 7 | 0.015 | ||
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.015 | ||
| Igfbp6 | insulin-like growth factor binding protein 6 | 0.015 | ||
| Hoxa1 | homeobox A1 | 0.015 | ||
| Gp5 | glycoprotein 5 (platelet) | 0.015 | ||
| Igfbp3 | insulin-like growth factor binding protein 3 | 0.015 | ||
| Upk3b | uroplakin 3B | 0.015 | ||
| Kdm6a | 4lysine (K)-specific demethylase 6A | 0.015 | ||
| Stat3 | signal transducer and activator of transcription 3 | 0.014 | ||
| Klf10 | Kruppel-like factor 10 | 0.014 | ||
| H2afx | H2A histone family, member X | 0.014 | ||
| Dpep1 | dipeptidase 1 (renal) | 0.014 | ||
| Epb4.2 | erythrocyte protein band 4.2 | 0.014 | ||
| Gaa | glucosidase, alpha, acid | 0.014 | ||
| Ctsg | cathepsin G | 0.014 | ||
| Mt1 | metallothionein 1 | 0.014 | ||
| Aurkb | aurora kinase B | 0.014 | ||
| Col4a5 | collagen, type IV, alpha 5 | 0.014 | ||
| Paics | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase | 0.014 | ||
| Gp9 | glycoprotein 9 (platelet) | 0.014 | ||
| Gata3 | GATA binding protein 3 | 0.013 | ||
| Eci2 | enoyl-Coenzyme A delta isomerase 2 | 0.013 | ||
| Mpo | myeloperoxidase | 0.013 | ||
| Slc2a10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 0.013 | ||
| Dusp1 | dual specificity phosphatase 1 | 0.013 | ||
| Rhbdf1 | rhomboid family 1 (Drosophila) | 0.013 | ||
| Pcolce | procollagen C-endopeptidase enhancer protein | 0.013 | ||
| P2rx1 | purinergic receptor P2X, ligand-gated ion channel, 1 | 0.013 | ||
| Mcam | melanoma cell adhesion molecule | 0.013 | ||
| Uqcrb | ubiquinol-cytochrome c reductase binding protein | 0.013 | ||
| Mmp8 | matrix metallopeptidase 8 | 0.013 | ||
| Zfp521 | zinc finger protein 521 | 0.013 | ||
| Chd2 | chromodomain helicase DNA binding protein 2 | 0.013 | ||
| Tspo2 | translocator protein 2 | 0.013 | ||
| Txn1 | thioredoxin 1 | 0.012 | ||
| Ltf | lactotransferrin | 0.012 | ||
| Zfp36l1 | zinc finger protein 36, C3H type-like 1 | 0.012 | ||
| X99384 | cDNA sequence X99384 | 0.012 | ||
| Ndufs1 | NADH dehydrogenase (ubiquinone) Fe-S protein 1 | 0.012 | ||
| Tlr2 | toll-like receptor 2 | 0.012 | ||
| Pklr | pyruvate kinase liver and red blood cell | 0.012 | ||
| Tshr | thyroid stimulating hormone receptor | 0.012 | ||
| Sqstm1 | sequestosome 1 | 0.012 | ||
| C3 | complement component 3 | 0.012 | ||
| Rdh10 | retinol dehydrogenase 10 (all-trans) | 0.012 | ||
| Gsto1 | glutathione S-transferase omega 1 | 0.012 | ||
| Pgk1 | phosphoglycerate kinase 1 | 0.012 | ||
| Ufc1 | ubiquitin-fold modifier conjugating enzyme 1 | 0.012 | ||
| Akr1a4 | aldo-keto reductase family 1, member A4 (aldehyde reductase) | 0.012 | ||
| Tpp1 | tripeptidyl peptidase I | 0.012 | ||
| Klk1b1 | kallikrein 1-related peptidase b1 | 0.012 | ||
| Pmpcb | peptidase (mitochondrial processing) beta | 0.012 | ||
| Mkl2 | MKL/myocardin-like 2 | 0.012 | ||
| Lpl | lipoprotein lipase | 0.012 | ||
| Lama4 | laminin, alpha 4 | 0.012 | ||
| Fh1 | fumarate hydratase 1 | 0.012 | ||
| Bgn | biglycan | 0.012 | ||
| Adam9 | a disintegrin and metallopeptidase domain 9 (meltrin gamma) | 0.012 | ||
| Lama2 | laminin, alpha 2 | 0.011 | ||
| Itga2b | integrin alpha 2b | 0.011 | ||
| Lamc2 | laminin, gamma 2 | 0.011 | ||
| Hdac7 | histone deacetylase 7 | 0.011 | ||
| Hic1 | hypermethylated in cancer 1 | 0.011 | ||
| Glrx3 | glutaredoxin 3 | 0.011 | ||
| Tgfb3 | transforming growth factor, beta 3 | 0.011 | ||
| Fmod | fibromodulin | 0.011 | ||
| Cul7 | cullin 7 | 0.011 | ||
| Pitrm1 | pitrilysin metallepetidase 1 | 0.011 | ||
| Dnmt1 | DNA methyltransferase (cytosine-5) 1 | 0.011 | ||
| H6pd | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) | 0.011 | ||
| Cngb1 | cyclic nucleotide gated channel beta 1 | 0.011 | ||
| Sulf1 | sulfatase 1 | 0.011 | ||
| Uqcrc2 | ubiquinol cytochrome c reductase core protein 2 | 0.011 | ||
| Hmgn1 | high mobility group nucleosomal binding domain 1 | 0.011 | ||
| Psma5 | proteasome (prosome, macropain) subunit, alpha type 5 | 0.011 | ||
| Col6a2 | collagen, type VI, alpha 2 | 0.011 | ||
| Ndufb6 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6 | 0.011 | ||
| Mrpl35 | mitochondrial ribosomal protein L35 | 0.011 | ||
| Alad | aminolevulinate, delta-, dehydratase | 0.011 | ||
| Smoc2 | SPARC related modular calcium binding 2 | 0.011 | ||
| Txndc17 | thioredoxin domain containing 17 | 0.010 | ||
| Cops6 | COP9 (constitutive photomorphogenic) homolog, subunit 6 (Arabidopsis thaliana) | 0.010 | ||
| Urod | uroporphyrinogen decarboxylase | 0.010 | ||
| Prickle2 | prickle homolog 2 (Drosophila) | 0.010 | ||
| Mfap4 | microfibrillar-associated protein 4 | 0.010 | ||
| Emp2 | epithelial membrane protein 2 | 0.010 | ||
| Dact1 | dapper homolog 1, antagonist of beta-catenin (xenopus) | 0.010 | ||
| Pdgfb | platelet derived growth factor, B polypeptide | 0.010 | ||
| Kel | Kell blood group | 0.010 | ||
| C1qtnf1 | C1q and tumor necrosis factor related protein 1 | 0.010 | ||
| Tars2 | threonyl-tRNA synthetase 2, mitochondrial (putative) | 0.010 | ||
| Hspa9 | heat shock protein 9 | 0.010 | ||
| Gadd45a | growth arrest and DNA-damage-inducible 45 alpha | 0.010 | ||
| Heph | hephaestin | 0.010 |