IMP: Integrative Multi-species Prediction

Mus musculus

108 genes annotated in mouse

neural tube formation

The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouseInclude functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "neural tube formation"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "neural tube formation" (in gray)

Name	Description	Probability	Func Analog Organism
Shh	sonic hedgehog	1.000
Gli3	GLI-Kruppel family member GLI3	1.000
Fgfr2	fibroblast growth factor receptor 2	1.000
Pax3	paired box gene 3	1.000
Otx2	orthodenticle homolog 2 (Drosophila)	1.000
Pax2	paired box gene 2	1.000
Vangl2	vang-like 2 (van gogh, Drosophila)	1.000
Pbx1	pre B-cell leukemia transcription factor 1	1.000
Tcfap2a	transcription factor AP-2, alpha	1.000
Pitx2	paired-like homeodomain transcription factor 2	0.999
Bmp4	bone morphogenetic protein 4	0.999
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.999
Eya1	eyes absent 1 homolog (Drosophila)	0.999
Fgf8	fibroblast growth factor 8	0.998
Smo	smoothened homolog (Drosophila)	0.997
Hoxa1	homeobox A1	0.997
Gli2	GLI-Kruppel family member GLI2	0.997
Hand1	heart and neural crest derivatives expressed transcript 1	0.997	Mouse
Sox2	SRY-box containing gene 2	0.997	Mouse
Msx1	homeobox, msh-like 1	0.997
Prrx1	paired related homeobox 1	0.997
Bmp7	bone morphogenetic protein 7	0.996	Mouse
Sall4	sal-like 4 (Drosophila)	0.995
Fgfr1	fibroblast growth factor receptor 1	0.995
Pax6	paired box gene 6	0.994
Rarg	retinoic acid receptor, gamma	0.993
Tbx1	T-box 1	0.990	Mouse
Zic3	zinc finger protein of the cerebellum 3	0.988	Mouse
Lhx1	LIM homeobox protein 1	0.986	Mouse
Foxc1	forkhead box C1	0.985
Vegfa	vascular endothelial growth factor A	0.984
Chrd	chordin	0.983
Ctnnb1	catenin (cadherin associated protein), beta 1	0.982
Gbx2	gastrulation brain homeobox 2	0.978
Nodal	nodal	0.975
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.972
Nog	noggin	0.967
Pax9	paired box gene 9	0.967	Mouse
Wnt5a	wingless-related MMTV integration site 5A	0.966
Dvl2	dishevelled 2, dsh homolog (Drosophila)	0.957
Foxc2	forkhead box C2	0.954
Fgf10	fibroblast growth factor 10	0.953
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.953	Mouse
Apc	adenomatosis polyposis coli	0.949
Sfrp2	secreted frizzled-related protein 2	0.948
Dlx5	distal-less homeobox 5	0.941
Dvl3	dishevelled 3, dsh homolog (Drosophila)	0.940
Emx2	empty spiracles homolog 2 (Drosophila)	0.940
Rarb	retinoic acid receptor, beta	0.939	Mouse
Msx2	homeobox, msh-like 2	0.936
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.926
Wnt3a	wingless-related MMTV integration site 3A	0.924	Mouse
Hes1	hairy and enhancer of split 1 (Drosophila)	0.921
En1	engrailed 1	0.916
Chd7	chromodomain helicase DNA binding protein 7	0.913
Foxg1	forkhead box G1	0.909
Hoxd13	homeobox D13	0.905
Prrx2	paired related homeobox 2	0.901
Emx1	empty spiracles homolog 1 (Drosophila)	0.888
Mks1	Meckel syndrome, type 1	0.886
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.886
Hoxa2	homeobox A2	0.883
Acvr1	activin A receptor, type 1	0.882
Hand2	heart and neural crest derivatives expressed transcript 2	0.881	Mouse
Pax8	paired box gene 8	0.879	Mouse
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.878
Rara	retinoic acid receptor, alpha	0.876
Pitx1	paired-like homeodomain transcription factor 1	0.876
Wt1	Wilms tumor 1 homolog	0.869
Hoxa13	homeobox A13	0.859
Ednra	endothelin receptor type A	0.853
Fzd1	frizzled homolog 1 (Drosophila)	0.838
Meox2	mesenchyme homeobox 2	0.834
Smad6	MAD homolog 6 (Drosophila)	0.831
Alx4	aristaless-like homeobox 4	0.830	Mouse
Ptch1	patched homolog 1	0.818
Lrp2	low density lipoprotein receptor-related protein 2	0.815	Mouse
Mn1	meningioma 1	0.814
Foxh1	forkhead box H1	0.798
Dvl1	dishevelled, dsh homolog 1 (Drosophila)	0.796
Jag1	jagged 1	0.796
Efna2	ephrin A2	0.795
Tbx2	T-box 2	0.793	Mouse
Smad3	MAD homolog 3 (Drosophila)	0.768
Tbx15	T-box 15	0.767	Mouse
Arid1a	AT rich interactive domain 1A (SWI-like)	0.767
Isl1	ISL1 transcription factor, LIM/homeodomain	0.760	Mouse
Ret	ret proto-oncogene	0.759
Lrp6	low density lipoprotein receptor-related protein 6	0.756
Tbx3	T-box 3	0.747	Mouse
Yap1	yes-associated protein 1	0.744
Hoxa5	homeobox A5	0.743
Otx1	orthodenticle homolog 1 (Drosophila)	0.736
Smad1	MAD homolog 1 (Drosophila)	0.729
Ift88	intraflagellar transport 88 homolog (Chlamydomonas)	0.728
Pou5f1	POU domain, class 5, transcription factor 1	0.716
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.712
Gas1	growth arrest specific 1	0.708
Tcfap2c	transcription factor AP-2, gamma	0.704	Mouse
Axin1	axin 1	0.703
Hoxa3	homeobox A3	0.702
Fgf3	fibroblast growth factor 3	0.702
Hoxa11	homeobox A11	0.698
Lmx1a	LIM homeobox transcription factor 1 alpha	0.691	Mouse
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.685
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.684
Shox2	short stature homeobox 2	0.675
Gdnf	glial cell line derived neurotrophic factor	0.673
Fzd7	frizzled homolog 7 (Drosophila)	0.670	Mouse
Alx1	ALX homeobox 1	0.668
Neurog2	neurogenin 2	0.666	Mouse
Hoxb6	homeobox B6	0.651
Gpc3	glypican 3	0.650
Wnt6	wingless-related MMTV integration site 6	0.641	Mouse
Sox11	SRY-box containing gene 11	0.641
Snai1	snail homolog 1 (Drosophila)	0.636
Rnf2	ring finger protein 2	0.634
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.629
Lef1	lymphoid enhancer binding factor 1	0.621
Tcf21	transcription factor 21	0.617
Hoxb4	homeobox B4	0.617
Eda	ectodysplasin-A	0.616
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.612
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.610
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.606
Uncx	UNC homeobox	0.599
Pten	phosphatase and tensin homolog	0.598
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.598
Zic2	zinc finger protein of the cerebellum 2	0.597
Tgfb2	transforming growth factor, beta 2	0.595
Sox7	SRY-box containing gene 7	0.594	Mouse
Dll1	delta-like 1 (Drosophila)	0.591
Tal2	T-cell acute lymphocytic leukemia 2	0.590	Mouse
Ephb2	Eph receptor B2	0.590
Lhx3	LIM homeobox protein 3	0.590	Mouse
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.589
Esrrb	estrogen related receptor, beta	0.583
Fgf15	fibroblast growth factor 15	0.573
Insm1	insulinoma-associated 1	0.569
Mecom	MDS1 and EVI1 complex locus	0.566
Gsc	goosecoid homeobox	0.560
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.559
Hoxd9	homeobox D9	0.557
Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.551
Tsc2	tuberous sclerosis 2	0.549
Hoxa9	homeobox A9	0.547
Sox3	SRY-box containing gene 3	0.544	Mouse
Pthlh	parathyroid hormone-like peptide	0.541
Gata3	GATA binding protein 3	0.539
Stk3	serine/threonine kinase 3 (Ste20, yeast homolog)	0.539
T	brachyury	0.537
Eomes	eomesodermin homolog (Xenopus laevis)	0.537	Mouse
Arhgef12	Rho guanine nucleotide exchange factor (GEF) 12	0.535
Cachd1	cache domain containing 1	0.522
Nf1	neurofibromatosis 1	0.521
Efs	embryonal Fyn-associated substrate	0.519
She	src homology 2 domain-containing transforming protein E	0.517
Fzd8	frizzled homolog 8 (Drosophila)	0.517	Mouse
Efnb2	ephrin B2	0.516
Pou3f3	POU domain, class 3, transcription factor 3	0.513
Wnt4	wingless-related MMTV integration site 4	0.513	Mouse
Notch2	Notch gene homolog 2 (Drosophila)	0.511
Meis2	Meis homeobox 2	0.508	Mouse
Nynrin	NYN domain and retroviral integrase containing	0.506
Foxd1	forkhead box D1	0.502
Hes5	hairy and enhancer of split 5 (Drosophila)	0.502
Notch3	Notch gene homolog 3 (Drosophila)	0.499
Aplnr	apelin receptor	0.492
Ptk7	PTK7 protein tyrosine kinase 7	0.479
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.475
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.467
Smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.465
Hoxc4	homeobox C4	0.457
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.455
Psen1	presenilin 1	0.453
Ebf3	early B-cell factor 3	0.452
Wnt7b	wingless-related MMTV integration site 7B	0.452	Mouse
Hoxd11	homeobox D11	0.445
Foxf1a	forkhead box F1a	0.443
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.441
Grb10	growth factor receptor bound protein 10	0.437
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.435
Megf8	multiple EGF-like-domains 8	0.434
Sox9	SRY-box containing gene 9	0.428	Mouse
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.426
Sox4	SRY-box containing gene 4	0.424
Hoxb3	homeobox B3	0.423
Tal1	T-cell acute lymphocytic leukemia 1	0.420	Mouse
Nfib	nuclear factor I/B	0.414
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.414
Rdh10	retinol dehydrogenase 10 (all-trans)	0.409
Foxa2	forkhead box A2	0.406
Tcfcp2l1	transcription factor CP2-like 1	0.406	Mouse
Bmper	BMP-binding endothelial regulator	0.404
Pdgfb	platelet derived growth factor, B polypeptide	0.404
Msi1	Musashi homolog 1(Drosophila)	0.401
Zic1	zinc finger protein of the cerebellum 1	0.401	Mouse
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.400
Kif3a	kinesin family member 3A	0.392
Fbln1	fibulin 1	0.391
Pou3f2	POU domain, class 3, transcription factor 2	0.390
Vasp	vasodilator-stimulated phosphoprotein	0.388
Traf6	TNF receptor-associated factor 6	0.385
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.380
Rspo1	R-spondin homolog (Xenopus laevis)	0.377
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.367
Epha4	Eph receptor A4	0.361
Smarcc1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.359
Fzd2	frizzled homolog 2 (Drosophila)	0.357
Sox17	SRY-box containing gene 17	0.357	Mouse
Nrp1	neuropilin 1	0.356
Bnc1	basonuclin 1	0.355
Efnb1	ephrin B1	0.354
Zfp503	zinc finger protein 503	0.344
Lmx1b	LIM homeobox transcription factor 1 beta	0.337	Mouse
Enah	enabled homolog (Drosophila)	0.336
Bcl2	B-cell leukemia/lymphoma 2	0.331
Gdf3	growth differentiation factor 3	0.328	Mouse
Ncoa3	nuclear receptor coactivator 3	0.327
Smad5	MAD homolog 5 (Drosophila)	0.326
Dcc	deleted in colorectal carcinoma	0.323
Sim2	single-minded homolog 2 (Drosophila)	0.322	Mouse
Npr3	natriuretic peptide receptor 3	0.318
Foxd2	forkhead box D2	0.318
Tlx3	T-cell leukemia, homeobox 3	0.317
Tcf15	transcription factor 15	0.317	Mouse
Notch1	Notch gene homolog 1 (Drosophila)	0.315
Smad4	MAD homolog 4 (Drosophila)	0.315
Gata4	GATA binding protein 4	0.314
Wnt1	wingless-related MMTV integration site 1	0.312	Mouse
Smad7	MAD homolog 7 (Drosophila)	0.311
Hif3a	hypoxia inducible factor 3, alpha subunit	0.311	Mouse
Foxj1	forkhead box J1	0.306
Fgfr3	fibroblast growth factor receptor 3	0.303
Gpr50	G-protein-coupled receptor 50	0.302
Arpc4	actin related protein 2/3 complex, subunit 4	0.302
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.297
Actb	actin, beta	0.296
Neurog1	neurogenin 1	0.294	Mouse
Rybp	RING1 and YY1 binding protein	0.291
Meis1	Meis homeobox 1	0.290	Mouse
Ephb3	Eph receptor B3	0.289
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.287
Runx2	runt related transcription factor 2	0.286
Wls	wntless homolog (Drosophila)	0.286
Pou3f4	POU domain, class 3, transcription factor 4	0.283
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.280
Cxadr	coxsackie virus and adenovirus receptor	0.280
Pou3f1	POU domain, class 3, transcription factor 1	0.280
Alx3	aristaless-like homeobox 3	0.279	Mouse
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.277
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.276
Gata2	GATA binding protein 2	0.275
Itga3	integrin alpha 3	0.273
Axin2	axin2	0.272
En2	engrailed 2	0.268
Wdr1	WD repeat domain 1	0.266
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.265
Fgf18	fibroblast growth factor 18	0.264
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.264
Gata6	GATA binding protein 6	0.262
Lhx9	LIM homeobox protein 9	0.260	Mouse
Hoxd3	homeobox D3	0.258
Nanog	Nanog homeobox	0.257
Isl2	insulin related protein 2 (islet 2)	0.256	Mouse
Dlg1	discs, large homolog 1 (Drosophila)	0.256
Ntn1	netrin 1	0.256
Onecut1	one cut domain, family member 1	0.253
Myod1	myogenic differentiation 1	0.252
Tead3	TEA domain family member 3	0.252
Capn6	calpain 6	0.251
Ldb2	LIM domain binding 2	0.250
Bmp2	bone morphogenetic protein 2	0.249	Mouse
Myf5	myogenic factor 5	0.247
Gtf2ird1	general transcription factor II I repeat domain-containing 1	0.247
Noto	notochord homolog (Xenopus laevis)	0.247
Mobkl1b	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.246
Rnf44	ring finger protein 44	0.243
Irx5	Iroquois related homeobox 5 (Drosophila)	0.242
Ahi1	Abelson helper integration site 1	0.240
Irs1	insulin receptor substrate 1	0.237
Kcne1l	potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene	0.236
Tead4	TEA domain family member 4	0.233	Mouse
Hoxb1	homeobox B1	0.232	Zebrafish
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.232
Nos3	nitric oxide synthase 3, endothelial cell	0.231
Irx2	Iroquois related homeobox 2 (Drosophila)	0.231
Tcf3	transcription factor 3	0.230
Hoxc5	homeobox C5	0.229
Ebf2	early B-cell factor 2	0.227
Tcof1	Treacher Collins Franceschetti syndrome 1, homolog	0.226
Pou4f3	POU domain, class 4, transcription factor 3	0.225
Barx1	BarH-like homeobox 1	0.223
Plxna1	plexin A1	0.223	Mouse
Sema5a	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.223
Lrp4	low density lipoprotein receptor-related protein 4	0.222	Mouse
Igfbpl1	insulin-like growth factor binding protein-like 1	0.222
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.222
Sh3rf1	SH3 domain containing ring finger 1	0.220
Cd2ap	CD2-associated protein	0.220
Twist2	twist homolog 2 (Drosophila)	0.220	Mouse
Sox21	SRY-box containing gene 21	0.217
Pax7	paired box gene 7	0.216	Mouse
Lhx6	LIM homeobox protein 6	0.215	Mouse
Pax1	paired box gene 1	0.214	Mouse
Acvr2b	activin receptor IIB	0.210
Ptf1a	pancreas specific transcription factor, 1a	0.209	Mouse
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.208
Pofut1	protein O-fucosyltransferase 1	0.208
Peg10	paternally expressed 10	0.207
Irx3	Iroquois related homeobox 3 (Drosophila)	0.207
Efna4	ephrin A4	0.206
Nfia	nuclear factor I/A	0.206
Vangl1	vang-like 1 (van gogh, Drosophila)	0.204	Mouse
Hoxa10	homeobox A10	0.203
Gsk3b	glycogen synthase kinase 3 beta	0.203
Sim1	single-minded homolog 1 (Drosophila)	0.203	Mouse
Gdf11	growth differentiation factor 11	0.202
Dab1	disabled homolog 1 (Drosophila)	0.201
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.200
Mrc2	mannose receptor, C type 2	0.199
Agap1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	0.199
Gja3	gap junction protein, alpha 3	0.199
Osr1	odd-skipped related 1 (Drosophila)	0.197
Fzd3	frizzled homolog 3 (Drosophila)	0.196
Sox10	SRY-box containing gene 10	0.196	Mouse
Fzd4	frizzled homolog 4 (Drosophila)	0.196	Mouse
Gja5	gap junction protein, alpha 5	0.194
Hif1a	hypoxia inducible factor 1, alpha subunit	0.193
Smarcd1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.192
Hoxd12	homeobox D12	0.191
Col4a3	collagen, type IV, alpha 3	0.191
Smad2	MAD homolog 2 (Drosophila)	0.190
Tead2	TEA domain family member 2	0.190
Hoxb7	homeobox B7	0.189
Glra1	glycine receptor, alpha 1 subunit	0.189
Edn3	endothelin 3	0.188
Nkx2-1	NK2 homeobox 1	0.188
Cdx1	caudal type homeobox 1	0.187
Dll4	delta-like 4 (Drosophila)	0.187
Tsc1	tuberous sclerosis 1	0.184
Gopc	golgi associated PDZ and coiled-coil motif containing	0.183
Kiss1	KiSS-1 metastasis-suppressor	0.183
Sav1	salvador homolog 1 (Drosophila)	0.183
Spry2	sprouty homolog 2 (Drosophila)	0.182
Irx1	Iroquois related homeobox 1 (Drosophila)	0.182
Parl	presenilin associated, rhomboid-like	0.181
Zfhx4	zinc finger homeodomain 4	0.181
Hoxb2	homeobox B2	0.181
Fign	fidgetin	0.181
Hoxb13	homeobox B13	0.180
Tlr4	toll-like receptor 4	0.179
Hoxb5	homeobox B5	0.179
Myo6	myosin VI	0.178
Myog	myogenin	0.178
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.178
Tlx2	T-cell leukemia, homeobox 2	0.178
Nrk	Nik related kinase	0.177
Wasf1	WASP family 1	0.176
Trp53	transformation related protein 53	0.176
Cdh6	cadherin 6	0.175
Plxna3	plexin A3	0.175	Mouse
Mmp15	matrix metallopeptidase 15	0.175
Kdm1a	lysine (K)-specific demethylase 1A	0.175
Adrb1	adrenergic receptor, beta 1	0.174
Disp1	dispatched homolog 1 (Drosophila)	0.174
Eif2c1	eukaryotic translation initiation factor 2C, 1	0.170
E2f1	E2F transcription factor 1	0.167
Crebbp	CREB binding protein	0.167
Lhx5	LIM homeobox protein 5	0.166	Mouse
Eef1a1	eukaryotic translation elongation factor 1 alpha 1	0.165
Tgfbr3	transforming growth factor, beta receptor III	0.165
Wwtr1	WW domain containing transcription regulator 1	0.164
Lama5	laminin, alpha 5	0.163
Wnk2	WNK lysine deficient protein kinase 2	0.162
Magel2	melanoma antigen, family L, 2	0.161
Kdr	kinase insert domain protein receptor	0.160
Btbd3	BTB (POZ) domain containing 3	0.160
Hs2st1	heparan sulfate 2-O-sulfotransferase 1	0.160
Dlk1	delta-like 1 homolog (Drosophila)	0.160
Tgfa	transforming growth factor alpha	0.160
Zfp185	zinc finger protein 185	0.159
Apaf1	apoptotic peptidase activating factor 1	0.159
Cbx2	chromobox homolog 2 (Drosophila Pc class)	0.159
Evl	Ena-vasodilator stimulated phosphoprotein	0.159	Mouse
Birc3	baculoviral IAP repeat-containing 3	0.159
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.159
Rgnef	Rho-guanine nucleotide exchange factor	0.157
Ptprb	protein tyrosine phosphatase, receptor type, B	0.157
Zfhx3	zinc finger homeobox 3	0.156
Vhl	von Hippel-Lindau tumor suppressor	0.155
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.154
Celsr1	cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)	0.154
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.153
Jag2	jagged 2	0.153
Hoxc6	homeobox C6	0.153
Per3	period homolog 3 (Drosophila)	0.153
Rxra	retinoid X receptor alpha	0.152
Pcdh12	protocadherin 12	0.152
Trim62	tripartite motif-containing 62	0.151
Pml	promyelocytic leukemia	0.150
Pkn2	protein kinase N2	0.150
Epas1	endothelial PAS domain protein 1	0.150	Mouse
Rax	retina and anterior neural fold homeobox	0.149
Emp2	epithelial membrane protein 2	0.148
Arvcf	armadillo repeat gene deleted in velo-cardio-facial syndrome	0.147
Phlda2	pleckstrin homology-like domain, family A, member 2	0.146
Cldn6	claudin 6	0.146
Arl10	ADP-ribosylation factor-like 10	0.145
Efnb3	ephrin B3	0.145
Emid2	EMI domain containing 2	0.144
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.144
Pcdh18	protocadherin 18	0.143
Pvrl1	poliovirus receptor-related 1	0.143
Nes	nestin	0.143
Wnt2b	wingless related MMTV integration site 2b	0.143	Mouse
Prc1	protein regulator of cytokinesis 1	0.142
Agrn	agrin	0.142
Msn	moesin	0.142
Fgf4	fibroblast growth factor 4	0.141
Lbx1	ladybird homeobox homolog 1 (Drosophila)	0.141
Myc	myelocytomatosis oncogene	0.140
Igf2	insulin-like growth factor 2	0.139
Sall3	sal-like 3 (Drosophila)	0.139	Mouse
Twsg1	twisted gastrulation homolog 1 (Drosophila)	0.138
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.138
Tcfap2b	transcription factor AP-2 beta	0.138	Mouse
Stra6	stimulated by retinoic acid gene 6	0.138
Matn4	matrilin 4	0.137
Fgf17	fibroblast growth factor 17	0.137
Actr3	ARP3 actin-related protein 3 homolog (yeast)	0.137
Ep300	E1A binding protein p300	0.137
Ece1	endothelin converting enzyme 1	0.136
Zic4	zinc finger protein of the cerebellum 4	0.136	Mouse
Nrbp2	nuclear receptor binding protein 2	0.135
Atp7b	ATPase, Cu++ transporting, beta polypeptide	0.133
Adra2b	adrenergic receptor, alpha 2b	0.133
Fjx1	four jointed box 1 (Drosophila)	0.132
Hmx1	H6 homeobox 1	0.132
Gli1	GLI-Kruppel family member GLI1	0.132
Tbx4	T-box 4	0.132	Mouse
Myf6	myogenic factor 6	0.131
Nf2	neurofibromatosis 2	0.130
Mmp24	matrix metallopeptidase 24	0.130
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.130
Hoxa4	homeobox A4	0.130
Wnt3	wingless-related MMTV integration site 3	0.129	Mouse
Zfp703	zinc finger protein 703	0.128
Id4	inhibitor of DNA binding 4	0.128
Eya4	eyes absent 4 homolog (Drosophila)	0.128
Cilp2	cartilage intermediate layer protein 2	0.128
Fev	FEV (ETS oncogene family)	0.128
Ptprg	protein tyrosine phosphatase, receptor type, G	0.127
Epn2	epsin 2	0.127
Lasp1	LIM and SH3 protein 1	0.126
Xiap	X-linked inhibitor of apoptosis	0.126
Sox1	SRY-box containing gene 1	0.126
Nacc1	nucleus accumbens associated 1, BEN and BTB (POZ) domain containing	0.125
Ski	ski sarcoma viral oncogene homolog (avian)	0.124
Adra2a	adrenergic receptor, alpha 2a	0.124
Ptprf	protein tyrosine phosphatase, receptor type, F	0.123
Foxp2	forkhead box P2	0.123
Zcchc14	zinc finger, CCHC domain containing 14	0.123
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.123
Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	0.122
Pbx3	pre B-cell leukemia transcription factor 3	0.122
Neurog3	neurogenin 3	0.122	Mouse
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.122
Hhex	hematopoietically expressed homeobox	0.122
Ccnb1	cyclin B1	0.121
Dlx1	distal-less homeobox 1	0.120
Usp43	ubiquitin specific peptidase 43	0.119
B3gat1	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)	0.119
Cbln1	cerebellin 1 precursor protein	0.119
Chuk	conserved helix-loop-helix ubiquitous kinase	0.119
Sall1	sal-like 1 (Drosophila)	0.119
Hesx1	homeobox gene expressed in ES cells	0.118
Plac1	placental specific protein 1	0.118
Hoxa7	homeobox A7	0.118
Gsx1	GS homeobox 1	0.118
Csnk2a1	casein kinase 2, alpha 1 polypeptide	0.117
Npas2	neuronal PAS domain protein 2	0.117
Ptpn13	protein tyrosine phosphatase, non-receptor type 13	0.117
Setdb1	SET domain, bifurcated 1	0.117
St8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.117
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.115
Igf2bp2	insulin-like growth factor 2 mRNA binding protein 2	0.111
Arnt	aryl hydrocarbon receptor nuclear translocator	0.111
Wnt11	wingless-related MMTV integration site 11	0.111	Mouse
Dlx6	distal-less homeobox 6	0.111
Dync1h1	dynein cytoplasmic 1 heavy chain 1	0.111
Bmp5	bone morphogenetic protein 5	0.111	Mouse
Egln1	EGL nine homolog 1 (C. elegans)	0.111
Myo10	myosin X	0.111
Hoxc8	homeobox C8	0.110
Pou4f2	POU domain, class 4, transcription factor 2	0.110
Lfng	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	0.110
Mnx1	motor neuron and pancreas homeobox 1	0.110
Hoxd1	homeobox D1	0.110
Aif1l	allograft inflammatory factor 1-like	0.110
Hic1	hypermethylated in cancer 1	0.110
Wwc1	WW, C2 and coiled-coil domain containing 1	0.109
Maf	avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog	0.109
Cacng7	calcium channel, voltage-dependent, gamma subunit 7	0.109
Gata1	GATA binding protein 1	0.108
Ptpru	protein tyrosine phosphatase, receptor type, U	0.108
Amotl2	angiomotin-like 2	0.108
Col13a1	collagen, type XIII, alpha 1	0.108
Hoxd8	homeobox D8	0.107
Stat5b	signal transducer and activator of transcription 5B	0.107
Apba2	amyloid beta (A4) precursor protein-binding, family A, member 2	0.107
Arsi	arylsulfatase i	0.107
Ank1	ankyrin 1, erythroid	0.107
Cer1	cerberus 1 homolog (Xenopus laevis)	0.106
Rpgrip1l	Rpgrip1-like	0.106
Ntn3	netrin 3	0.106
Ybx2	Y box protein 2	0.105
Slc16a2	solute carrier family 16 (monocarboxylic acid transporters), member 2	0.105
Trp63	transformation related protein 63	0.104
Mpz	myelin protein zero	0.104
Trrap	transformation/transcription domain-associated protein	0.104
Gsx2	GS homeobox 2	0.104
Grid1	glutamate receptor, ionotropic, delta 1	0.103
Cep55	centrosomal protein 55	0.103
Icam4	intercellular adhesion molecule 4, Landsteiner-Wiener blood group	0.103
Fscn1	fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)	0.103
Ldb1	LIM domain binding 1	0.103
Cdk1	cyclin-dependent kinase 1	0.103
Sfrp1	secreted frizzled-related protein 1	0.103
Apcdd1	adenomatosis polyposis coli down-regulated 1	0.103
Ssbp3	single-stranded DNA binding protein 3	0.102
Btbd17	BTB (POZ) domain containing 17	0.102
Tmpo	thymopoietin	0.101
Evx1	even skipped homeotic gene 1 homolog	0.101
Irx4	Iroquois related homeobox 4 (Drosophila)	0.101
Cpd	carboxypeptidase D	0.101
Hoxd4	homeobox D4	0.101
Meox1	mesenchyme homeobox 1	0.101
Actg1	actin, gamma, cytoplasmic 1	0.100
Bcl10	B-cell leukemia/lymphoma 10	0.100
Ncoa1	nuclear receptor coactivator 1	0.100
Des	desmin	0.100
Dlx4	distal-less homeobox 4	0.099
Zbtb46	zinc finger and BTB domain containing 46	0.099
Foxd3	forkhead box D3	0.099
Numa1	nuclear mitotic apparatus protein 1	0.099
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.099
Foxb1	forkhead box B1	0.099
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.099
Tdgf1	teratocarcinoma-derived growth factor 1	0.099
Twist1	twist homolog 1 (Drosophila)	0.099
Cc2d2a	coiled-coil and C2 domain containing 2A	0.099
Crb2	crumbs homolog 2 (Drosophila)	0.099
Tpbg	trophoblast glycoprotein	0.098
Mycl1	v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)	0.098
Kif11	kinesin family member 11	0.097
Cldn4	claudin 4	0.097
Gpr27	G protein-coupled receptor 27	0.097
Tgfbr2	transforming growth factor, beta receptor II	0.096
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.096
Zfp316	zinc finger protein 316	0.095
Nppb	natriuretic peptide type B	0.095
Foxa1	forkhead box A1	0.095
Mesp1	mesoderm posterior 1	0.095
Igf1r	insulin-like growth factor I receptor	0.095
Trpm7	transient receptor potential cation channel, subfamily M, member 7	0.094
Pbx2	pre B-cell leukemia transcription factor 2	0.094
Zeb1	zinc finger E-box binding homeobox 1	0.094	Mouse
Angpt1	angiopoietin 1	0.094
Sox13	SRY-box containing gene 13	0.094
Fhl3	four and a half LIM domains 3	0.094
Rest	RE1-silencing transcription factor	0.094
Tecta	tectorin alpha	0.093
Adam10	a disintegrin and metallopeptidase domain 10	0.093
Prdm16	PR domain containing 16	0.093
Baiap2l1	BAI1-associated protein 2-like 1	0.093
Ctnnd1	catenin (cadherin associated protein), delta 1	0.093
Zim1	zinc finger, imprinted 1	0.093
Hrc	histidine rich calcium binding protein	0.092
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.092
Il11	interleukin 11	0.092
Edar	ectodysplasin-A receptor	0.092
Ednrb	endothelin receptor type B	0.092
Fzd6	frizzled homolog 6 (Drosophila)	0.092
Hoxa6	homeobox A6	0.091
Nkd1	naked cuticle 1 homolog (Drosophila)	0.091
Rac1	RAS-related C3 botulinum substrate 1	0.091
Cdh3	cadherin 3	0.090	Zebrafish
Mta2	metastasis-associated gene family, member 2	0.090
Trove2	TROVE domain family, member 2	0.090
Zswim6	zinc finger, SWIM domain containing 6	0.089
Mapk12	mitogen-activated protein kinase 12	0.089
Wdr19	WD repeat domain 19	0.089
Hip1	huntingtin interacting protein 1	0.089
Arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.089
Col9a1	collagen, type IX, alpha 1	0.089
Aldh1a3	aldehyde dehydrogenase family 1, subfamily A3	0.089
Arx	aristaless related homeobox	0.089	Mouse
Thra	thyroid hormone receptor alpha	0.088	Mouse
Igf2bp1	insulin-like growth factor 2 mRNA binding protein 1	0.088
Trim8	tripartite motif-containing 8	0.088
Slc27a3	solute carrier family 27 (fatty acid transporter), member 3	0.087
Lhx2	LIM homeobox protein 2	0.087
Pitx3	paired-like homeodomain transcription factor 3	0.087
Irs3	insulin receptor substrate 3	0.087
Ptgfrn	prostaglandin F2 receptor negative regulator	0.087
Pcsk6	proprotein convertase subtilisin/kexin type 6	0.086
Hes3	hairy and enhancer of split 3 (Drosophila)	0.086
Nkx2-9	NK2 transcription factor related, locus 9 (Drosophila)	0.086
Hspb7	heat shock protein family, member 7 (cardiovascular)	0.085
Bmp6	bone morphogenetic protein 6	0.085	Mouse
Dach1	dachshund 1 (Drosophila)	0.085
Chrna7	cholinergic receptor, nicotinic, alpha polypeptide 7	0.085
Ptpn12	protein tyrosine phosphatase, non-receptor type 12	0.085
Cux1	cut-like homeobox 1	0.085
Wiz	widely-interspaced zinc finger motifs	0.085
Wnt9a	wingless-type MMTV integration site 9A	0.085	Mouse
Ndufs1	NADH dehydrogenase (ubiquinone) Fe-S protein 1	0.085
Sox18	SRY-box containing gene 18	0.084	Mouse
Lmo2	LIM domain only 2	0.084	Mouse
Arhgef2	rho/rac guanine nucleotide exchange factor (GEF) 2	0.084
Klf3	Kruppel-like factor 3 (basic)	0.084
Prox1	prospero-related homeobox 1	0.084
Rbl1	retinoblastoma-like 1 (p107)	0.084
Robo3	roundabout homolog 3 (Drosophila)	0.084
Epha8	Eph receptor A8	0.084
Dmbx1	diencephalon/mesencephalon homeobox 1	0.084
Ddah2	dimethylarginine dimethylaminohydrolase 2	0.084
Asb10	ankyrin repeat and SOCS box-containing 10	0.084
Epor	erythropoietin receptor	0.083
Etl4	enhancer trap locus 4	0.083
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.083
Hoxb9	homeobox B9	0.083
Cask	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	0.083
Nrtn	neurturin	0.082
Zfp219	zinc finger protein 219	0.082
Kcnk2	potassium channel, subfamily K, member 2	0.082
Gpr124	G protein-coupled receptor 124	0.082
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.082	Mouse
Hoxc9	homeobox C9	0.082
Myst3	MYST histone acetyltransferase (monocytic leukemia) 3	0.081
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.081
Vax1	ventral anterior homeobox containing gene 1	0.081
Gnrhr	gonadotropin releasing hormone receptor	0.080
Cd44	CD44 antigen	0.080
Fam83h	family with sequence similarity 83, member H	0.080
Krt36	keratin 36	0.080
Mid2	midline 2	0.080
Cd40	CD40 antigen	0.079
Ckap2	cytoskeleton associated protein 2	0.079
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.078
Mgat3	mannoside acetylglucosaminyltransferase 3	0.078
Foxn4	forkhead box N4	0.078
Tnni1	troponin I, skeletal, slow 1	0.078
Robo1	roundabout homolog 1 (Drosophila)	0.077
Rnd3	Rho family GTPase 3	0.077
Dlx3	distal-less homeobox 3	0.077
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.077
Zfp532	zinc finger protein 532	0.077
Trp53bp2	transformation related protein 53 binding protein 2	0.077
Racgap1	Rac GTPase-activating protein 1	0.076
Upk3b	uroplakin 3B	0.076
Slc22a23	solute carrier family 22, member 23	0.076
Sin3a	transcriptional regulator, SIN3A (yeast)	0.076
Ephb4	Eph receptor B4	0.076
Vldlr	very low density lipoprotein receptor	0.076
Nkx6-1	NK6 homeobox 1	0.075
Syt7	synaptotagmin VII	0.075
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.075
Tada2a	transcriptional adaptor 2A	0.075
Plcb3	phospholipase C, beta 3	0.075
Dlx2	distal-less homeobox 2	0.075
Ly6h	lymphocyte antigen 6 complex, locus H	0.074
Zfr2	zinc finger RNA binding protein 2	0.074
Plxna2	plexin A2	0.074	Mouse
Lyz2	lysozyme 2	0.074
Sertad2	SERTA domain containing 2	0.074
Phox2b	paired-like homeobox 2b	0.074
Vstm2b	V-set and transmembrane domain containing 2B	0.074
Onecut2	one cut domain, family member 2	0.074
Ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.074
Klf6	Kruppel-like factor 6	0.073
Gna13	guanine nucleotide binding protein, alpha 13	0.073
Tspan9	tetraspanin 9	0.073
Ikbkb	inhibitor of kappaB kinase beta	0.073
Itga8	integrin alpha 8	0.073
Fzd9	frizzled homolog 9 (Drosophila)	0.073	Mouse
Insm2	insulinoma-associated 2	0.072
Bcam	basal cell adhesion molecule	0.072
Olfr71	olfactory receptor 71	0.072
Slc22a6	solute carrier family 22 (organic anion transporter), member 6	0.072
Mdfi	MyoD family inhibitor	0.072
Aff1	AF4/FMR2 family, member 1	0.072
Rpl6	ribosomal protein L6	0.072
Pnpla6	patatin-like phospholipase domain containing 6	0.071
Card11	caspase recruitment domain family, member 11	0.071
Tab2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.071
Kif13a	kinesin family member 13A	0.071
Dmrt3	doublesex and mab-3 related transcription factor 3	0.071
Gna11	guanine nucleotide binding protein, alpha 11	0.071
Dhh	desert hedgehog	0.070
Gnai3	guanine nucleotide binding protein (G protein), alpha inhibiting 3	0.070
Dbx1	developing brain homeobox 1	0.070
Ssbp2	single-stranded DNA binding protein 2	0.070
Gnao1	guanine nucleotide binding protein, alpha O	0.070
Cdh23	cadherin 23 (otocadherin)	0.070
Scn5a	sodium channel, voltage-gated, type V, alpha	0.070
Pak2	p21 protein (Cdc42/Rac)-activated kinase 2	0.070
Crabp2	cellular retinoic acid binding protein II	0.070
Ddr2	discoidin domain receptor family, member 2	0.070
Spna2	spectrin alpha 2	0.070
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.070
Satb2	special AT-rich sequence binding protein 2	0.070
Efna5	ephrin A5	0.069
Mmp11	matrix metallopeptidase 11	0.069
Epha3	Eph receptor A3	0.069
Cntn2	contactin 2	0.069
Foxl2	forkhead box L2	0.069
Creb1	cAMP responsive element binding protein 1	0.068
Hbb-bh1	hemoglobin Z, beta-like embryonic chain	0.068
Vav2	vav 2 oncogene	0.068
Amhr2	anti-Mullerian hormone type 2 receptor	0.068
Scrt2	scratch homolog 2, zinc finger protein (Drosophila)	0.067
Ascl2	achaete-scute complex homolog 2 (Drosophila)	0.067
Tubb5	tubulin, beta 5	0.067
Ptch2	patched homolog 2	0.067	Mouse
Acvr2a	activin receptor IIA	0.067
Cdx2	caudal type homeobox 2	0.067
Adcy9	adenylate cyclase 9	0.067
Sdc3	syndecan 3	0.067
Tmod3	tropomodulin 3	0.067
Fgf9	fibroblast growth factor 9	0.066
Cdc42se1	CDC42 small effector 1	0.066
Cdc42ep1	CDC42 effector protein (Rho GTPase binding) 1	0.066
Ncor1	nuclear receptor co-repressor 1	0.066
Mta1	metastasis associated 1	0.065
Sykb	spleen tyrosine kinase	0.065
Hcfc1	host cell factor C1	0.065
Il18	interleukin 18	0.065
Kcnmb1	potassium large conductance calcium-activated channel, subfamily M, beta member 1	0.065
Aim2	absent in melanoma 2	0.065
Atp5a1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1	0.065
Fli1	Friend leukemia integration 1	0.065
Hmx3	H6 homeobox 3	0.065
Nkain1	Na+/K+ transporting ATPase interacting 1	0.065
Lman1l	lectin, mannose-binding 1 like	0.065
Sp8	trans-acting transcription factor 8	0.065
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.065
Nfya	nuclear transcription factor-Y alpha	0.065
Smarcc2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	0.065