Process View
The process in which duplicated centrosome components move away from each other. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle.
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "centrosome separation"
Name | Description | Probability | Func Analog Organism | |
---|---|---|---|---|
Ndel1 | nuclear distribution gene E-like homolog 1 (A. nidulans) | 0.967 | ||
Pafah1b1 | platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 | 0.866 | Worm Fly | |
Ccnb1 | cyclin B1 | 0.839 | ||
Hmmr | hyaluronan mediated motility receptor (RHAMM) | 0.478 | ||
Nek2 | NIMA (never in mitosis gene a)-related expressed kinase 2 | 0.452 | Human | |
Prc1 | protein regulator of cytokinesis 1 | 0.437 | ||
Kif4 | kinesin family member 4 | 0.423 | ||
Ccna2 | cyclin A2 | 0.421 | ||
Kif2c | kinesin family member 2C | 0.419 | ||
Ncoa2 | nuclear receptor coactivator 2 | 0.398 | ||
Bub1 | budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) | 0.376 | ||
Plk1 | polo-like kinase 1 (Drosophila) | 0.375 | ||
Anln | anillin, actin binding protein | 0.364 | ||
Cdk1 | cyclin-dependent kinase 1 | 0.345 | ||
Cdc20 | cell division cycle 20 homolog (S. cerevisiae) | 0.324 | ||
Mis18bp1 | MIS18 binding protein 1 | 0.310 | ||
Kif23 | kinesin family member 23 | 0.294 | ||
Kif20a | kinesin family member 20A | 0.291 | ||
1110004F10Rik | RIKEN cDNA 1110004F10 gene | 0.260 | ||
Rab18 | RAB18, member RAS oncogene family | 0.227 | ||
Aspm | asp (abnormal spindle)-like, microcephaly associated (Drosophila) | 0.214 | ||
Dtl | denticleless homolog (Drosophila) | 0.182 | ||
Dlgap5 | discs, large (Drosophila) homolog-associated protein 5 | 0.180 | ||
Stil | Scl/Tal1 interrupting locus | 0.179 | ||
Pcna | proliferating cell nuclear antigen | 0.173 | ||
Rab5a | RAB5A, member RAS oncogene family | 0.173 | ||
Plk4 | polo-like kinase 4 (Drosophila) | 0.165 | ||
Asf1b | ASF1 anti-silencing function 1 homolog B (S. cerevisiae) | 0.161 | ||
Cenpa | centromere protein A | 0.159 | ||
E2f8 | E2F transcription factor 8 | 0.156 | ||
Strn3 | striatin, calmodulin binding protein 3 | 0.155 | ||
Ube2d3 | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 0.151 | ||
Atp6v1d | ATPase, H+ transporting, lysosomal V1 subunit D | 0.151 | ||
Kif11 | kinesin family member 11 | 0.149 | ||
Ccnb2 | cyclin B2 | 0.148 | ||
Ckap2 | cytoskeleton associated protein 2 | 0.148 | ||
Erh | enhancer of rudimentary homolog (Drosophila) | 0.140 | ||
Racgap1 | Rac GTPase-activating protein 1 | 0.132 | ||
Cenpf | centromere protein F | 0.128 | ||
C330027C09Rik | RIKEN cDNA C330027C09 gene | 0.128 | ||
Smc2 | structural maintenance of chromosomes 2 | 0.127 | ||
Mastl | microtubule associated serine/threonine kinase-like | 0.126 | ||
Ncaph | non-SMC condensin I complex, subunit H | 0.125 | ||
Ppp1cb | protein phosphatase 1, catalytic subunit, beta isoform | 0.125 | ||
Top2a | topoisomerase (DNA) II alpha | 0.111 | ||
Zfand5 | zinc finger, AN1-type domain 5 | 0.110 | ||
Ttk | Ttk protein kinase | 0.109 | ||
Fam64a | family with sequence similarity 64, member A | 0.108 | ||
Ywhae | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 0.104 | ||
Ppp2r1a | protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform | 0.097 | ||
H2afx | H2A histone family, member X | 0.094 | ||
Dync1i1 | dynein cytoplasmic 1 intermediate chain 1 | 0.093 | ||
Dna2 | DNA replication helicase 2 homolog (yeast) | 0.091 | ||
Dynll1 | dynein light chain LC8-type 1 | 0.082 | ||
Zfp617 | zinc finger protein 617 | 0.076 | ||
Gtse1 | G two S phase expressed protein 1 | 0.072 | ||
Eif4a2 | eukaryotic translation initiation factor 4A2 | 0.072 | ||
Csde1 | cold shock domain containing E1, RNA binding | 0.072 | ||
Gsg2 | germ cell-specific gene 2 | 0.069 | ||
Clip1 | CAP-GLY domain containing linker protein 1 | 0.067 | ||
Thoc4 | THO complex 4 | 0.064 | ||
Cdc25c | cell division cycle 25 homolog C (S. pombe) | 0.062 | ||
Kif22 | kinesin family member 22 | 0.062 | ||
Lmnb1 | lamin B1 | 0.058 | ||
Ywhaz | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.058 | ||
Exo1 | exonuclease 1 | 0.055 | ||
Dtnb | dystrobrevin, beta | 0.054 | ||
Mcm3 | minichromosome maintenance deficient 3 (S. cerevisiae) | 0.054 | ||
Hccs | holocytochrome c synthetase | 0.054 | ||
Serinc1 | serine incorporator 1 | 0.054 | ||
Aurkb | aurora kinase B | 0.053 | Fly | |
Rnf11 | ring finger protein 11 | 0.053 | ||
Igbp1 | immunoglobulin (CD79A) binding protein 1 | 0.053 | ||
Ywhag | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 0.052 | ||
Ect2 | ect2 oncogene | 0.051 | ||
Azin1 | antizyme inhibitor 1 | 0.049 | ||
Eif3j | eukaryotic translation initiation factor 3, subunit J | 0.046 | ||
Foxm1 | forkhead box M1 | 0.046 | ||
Mapk8ip3 | mitogen-activated protein kinase 8 interacting protein 3 | 0.045 | ||
Rab1 | RAB1, member RAS oncogene family | 0.043 | ||
Brca1 | breast cancer 1 | 0.042 | ||
Ska1 | spindle and kinetochore associated complex subunit 1 | 0.041 | ||
Ccdc99 | coiled-coil domain containing 99 | 0.041 | ||
Kif5a | kinesin family member 5A | 0.040 | Fly | |
Tfdp1 | transcription factor Dp 1 | 0.040 | ||
Iqgap3 | IQ motif containing GTPase activating protein 3 | 0.039 | ||
Ywhah | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 0.039 | ||
Ccnf | cyclin F | 0.039 | ||
Diap3 | diaphanous homolog 3 (Drosophila) | 0.037 | ||
Eme1 | essential meiotic endonuclease 1 homolog 1 (S. pombe) | 0.037 | ||
Golph3 | golgi phosphoprotein 3 | 0.036 | ||
Bzw1 | basic leucine zipper and W2 domains 1 | 0.036 | ||
Ppp3r1 | protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) | 0.035 | ||
Ubl3 | ubiquitin-like 3 | 0.035 | ||
Ppih | peptidyl prolyl isomerase H | 0.035 | ||
Mgea5 | meningioma expressed antigen 5 (hyaluronidase) | 0.035 | ||
Sult4a1 | sulfotransferase family 4A, member 1 | 0.035 | ||
Srsf2 | serine/arginine-rich splicing factor 2 | 0.034 | ||
Capza2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.033 | ||
Vapa | vesicle-associated membrane protein, associated protein A | 0.033 | ||
Cdca5 | cell division cycle associated 5 | 0.033 | ||
Fam54a | family with sequence similarity 54, member A | 0.032 | ||
2810474O19Rik | RIKEN cDNA 2810474O19 gene | 0.032 | ||
Trip13 | thyroid hormone receptor interactor 13 | 0.032 | ||
Ppm1a | protein phosphatase 1A, magnesium dependent, alpha isoform | 0.032 | ||
Psmc3ip | proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein | 0.032 | ||
Spag5 | sperm associated antigen 5 | 0.032 | ||
Mcm10 | minichromosome maintenance deficient 10 (S. cerevisiae) | 0.030 | ||
Mki67 | antigen identified by monoclonal antibody Ki 67 | 0.030 | ||
Nusap1 | nucleolar and spindle associated protein 1 | 0.030 | ||
Ranbp9 | RAN binding protein 9 | 0.029 | ||
Ywhab | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | 0.029 | ||
Cenpk | centromere protein K | 0.029 | ||
Mad2l1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.028 | ||
Taok1 | TAO kinase 1 | 0.027 | ||
2810417H13Rik | RIKEN cDNA 2810417H13 gene | 0.027 | ||
Chek2 | CHK2 checkpoint homolog (S. pombe) | 0.027 | ||
Kpna2 | karyopherin (importin) alpha 2 | 0.027 | ||
Tmem30a | transmembrane protein 30A | 0.026 | ||
Dsn1 | DSN1, MIND kinetochore complex component, homolog (S. cerevisiae) | 0.026 | ||
Rab10 | RAB10, member RAS oncogene family | 0.026 | ||
Hspa8 | heat shock protein 8 | 0.026 | ||
Eif4g2 | eukaryotic translation initiation factor 4, gamma 2 | 0.026 | ||
Yipf4 | Yip1 domain family, member 4 | 0.025 | ||
Ifrd1 | interferon-related developmental regulator 1 | 0.025 | ||
Cul3 | cullin 3 | 0.025 | ||
Cdc45 | cell division cycle 45 homolog (S. cerevisiae) | 0.024 | ||
Cab39 | calcium binding protein 39 | 0.024 | ||
Depdc1a | DEP domain containing 1a | 0.024 | ||
A930001N09Rik | RIKEN cDNA A930001N09 gene | 0.024 | ||
Nedd1 | neural precursor cell expressed, developmentally down-regulated gene 1 | 0.023 | ||
Fbxl3 | F-box and leucine-rich repeat protein 3 | 0.023 | ||
Atl2 | atlastin GTPase 2 | 0.023 | ||
H3f3a | H3 histone, family 3A | 0.023 | ||
Smap1 | stromal membrane-associated protein 1 | 0.023 | ||
Cdca8 | cell division cycle associated 8 | 0.023 | ||
Rtn4 | reticulon 4 | 0.023 | ||
Rpgrip1l | Rpgrip1-like | 0.022 | ||
Nuf2 | NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae) | 0.022 | ||
Tpx2 | TPX2, microtubule-associated protein homolog (Xenopus laevis) | 0.021 | ||
Kif5c | kinesin family member 5C | 0.021 | Fly | |
Qk | quaking | 0.021 | ||
Cdkn3 | cyclin-dependent kinase inhibitor 3 | 0.021 | ||
Birc5 | baculoviral IAP repeat-containing 5 | 0.021 | ||
Dnajb9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.021 | ||
Fam83d | family with sequence similarity 83, member D | 0.021 | ||
Tiparp | TCDD-inducible poly(ADP-ribose) polymerase | 0.021 | ||
Nptn | neuroplastin | 0.020 | ||
Trim59 | tripartite motif-containing 59 | 0.020 | ||
Rad51ap1 | RAD51 associated protein 1 | 0.020 | ||
Lin9 | lin-9 homolog (C. elegans) | 0.020 | ||
Rab6 | RAB6, member RAS oncogene family | 0.020 | ||
Mpp5 | membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) | 0.020 | ||
Ptp4a1 | protein tyrosine phosphatase 4a1 | 0.020 | ||
Rab11a | RAB11a, member RAS oncogene family | 0.019 | ||
Rab2a | RAB2A, member RAS oncogene family | 0.019 | ||
Hap1 | huntingtin-associated protein 1 | 0.019 | ||
Cdc7 | cell division cycle 7 (S. cerevisiae) | 0.019 | ||
Macf1 | microtubule-actin crosslinking factor 1 | 0.019 | ||
Kpna1 | karyopherin (importin) alpha 1 | 0.019 | ||
Zfand6 | zinc finger, AN1-type domain 6 | 0.019 | ||
Ube2g1 | ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans) | 0.019 | ||
Ergic2 | ERGIC and golgi 2 | 0.018 | ||
Pak1ip1 | PAK1 interacting protein 1 | 0.018 | ||
Lancl2 | LanC (bacterial lantibiotic synthetase component C)-like 2 | 0.018 | ||
Sass6 | spindle assembly 6 homolog (C. elegans) | 0.018 | ||
Homer1 | homer homolog 1 (Drosophila) | 0.017 | ||
Casc5 | cancer susceptibility candidate 5 | 0.017 | ||
Hsp90aa1 | heat shock protein 90, alpha (cytosolic), class A member 1 | 0.017 | ||
Sept7 | septin 7 | 0.017 | ||
Dync1h1 | dynein cytoplasmic 1 heavy chain 1 | 0.017 | ||
Clasp1 | CLIP associating protein 1 | 0.017 | ||
Psmd14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.017 | ||
Paip2 | polyadenylate-binding protein-interacting protein 2 | 0.016 | ||
Prr11 | proline rich 11 | 0.016 | ||
Pole2 | polymerase (DNA directed), epsilon 2 (p59 subunit) | 0.016 | ||
Cdc6 | cell division cycle 6 homolog (S. cerevisiae) | 0.016 | ||
Depdc1b | DEP domain containing 1B | 0.016 | ||
Snap25 | synaptosomal-associated protein 25 | 0.016 | ||
Defa3 | defensin, alpha, 3 | 0.016 | ||
Kif5b | kinesin family member 5B | 0.016 | Fly | |
Lims1 | LIM and senescent cell antigen-like domains 1 | 0.016 | ||
Ndfip2 | Nedd4 family interacting protein 2 | 0.016 | ||
Mybl2 | myeloblastosis oncogene-like 2 | 0.016 | ||
Tbc1d4 | TBC1 domain family, member 4 | 0.016 | ||
Blzf1 | basic leucine zipper nuclear factor 1 | 0.016 | ||
Fanci | Fanconi anemia, complementation group I | 0.016 | ||
Aurka | aurora kinase A | 0.015 | ||
Csnk1a1 | casein kinase 1, alpha 1 | 0.015 | ||
Eif4a1 | eukaryotic translation initiation factor 4A1 | 0.015 | ||
Fam134b | family with sequence similarity 134, member B | 0.015 | ||
Kpna3 | karyopherin (importin) alpha 3 | 0.015 | ||
Zc3h15 | zinc finger CCCH-type containing 15 | 0.015 | ||
Cpeb2 | cytoplasmic polyadenylation element binding protein 2 | 0.015 | ||
Tbc1d15 | TBC1 domain family, member 15 | 0.015 | ||
Rbbp8 | retinoblastoma binding protein 8 | 0.015 | ||
Brp44 | brain protein 44 | 0.015 | ||
Ankrd13c | ankyrin repeat domain 13c | 0.015 | ||
Arih1 | ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila) | 0.015 | ||
Nefh | neurofilament, heavy polypeptide | 0.014 | ||
Ube2t | ubiquitin-conjugating enzyme E2T (putative) | 0.014 | ||
Neil3 | nei like 3 (E. coli) | 0.014 | ||
Rheb | Ras homolog enriched in brain | 0.014 | ||
Nup50 | nucleoporin 50 | 0.014 | ||
Slmap | sarcolemma associated protein | 0.014 | ||
Prkar1a | protein kinase, cAMP dependent regulatory, type I, alpha | 0.014 | ||
Wdr37 | WD repeat domain 37 | 0.014 | ||
Cacybp | calcyclin binding protein | 0.014 | ||
Bub1b | budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) | 0.014 | ||
Fam103a1 | family with sequence similarity 103, member A1 | 0.014 | ||
Vdac2 | voltage-dependent anion channel 2 | 0.014 | ||
Ube2n | ubiquitin-conjugating enzyme E2N | 0.014 | ||
Rab12 | RAB12, member RAS oncogene family | 0.014 | ||
Dld | dihydrolipoamide dehydrogenase | 0.014 | ||
Pask | PAS domain containing serine/threonine kinase | 0.014 | ||
Ubxn4 | UBX domain protein 4 | 0.014 | ||
Klc1 | kinesin light chain 1 | 0.014 | ||
5730590G19Rik | RIKEN cDNA 5730590G19 gene | 0.013 | ||
H2afz | H2A histone family, member Z | 0.013 | ||
Mapre1 | microtubule-associated protein, RP/EB family, member 1 | 0.013 | ||
Itfg1 | integrin alpha FG-GAP repeat containing 1 | 0.013 | ||
Tra2b | transformer 2 beta homolog (Drosophila) | 0.013 | ||
Fbxw11 | F-box and WD-40 domain protein 11 | 0.013 | ||
Ppp2cb | protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform | 0.013 | ||
Ppp1cc | protein phosphatase 1, catalytic subunit, gamma isoform | 0.013 | ||
Xrn2 | 5'-3' exoribonuclease 2 | 0.013 | ||
Elavl4 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D) | 0.013 | ||
Nefl | neurofilament, light polypeptide | 0.013 | ||
Pbk | PDZ binding kinase | 0.013 | ||
Mef2a | myocyte enhancer factor 2A | 0.013 | ||
Cript | cysteine-rich PDZ-binding protein | 0.012 | ||
Kif21a | kinesin family member 21A | 0.012 | ||
Sh3gl2 | SH3-domain GRB2-like 2 | 0.012 | ||
Cenpn | centromere protein N | 0.012 | ||
Mxd3 | Max dimerization protein 3 | 0.012 | ||
Zfx | zinc finger protein X-linked | 0.012 | ||
Mbnl1 | muscleblind-like 1 (Drosophila) | 0.012 | ||
Pole4 | polymerase (DNA-directed), epsilon 4 (p12 subunit) | 0.012 | ||
Polb | polymerase (DNA directed), beta | 0.012 | ||
Cdca7l | cell division cycle associated 7 like | 0.012 | ||
Tyms | thymidylate synthase | 0.012 | ||
Chmp5 | chromatin modifying protein 5 | 0.012 | ||
Rbm18 | RNA binding motif protein 18 | 0.012 | ||
Usp8 | ubiquitin specific peptidase 8 | 0.012 | ||
Mgat2 | mannoside acetylglucosaminyltransferase 2 | 0.012 | ||
Kif18a | kinesin family member 18A | 0.012 | Fly | |
Ppp3ca | protein phosphatase 3, catalytic subunit, alpha isoform | 0.012 | ||
Ccdc123 | coiled-coil domain containing 123 | 0.012 | ||
Ube2c | ubiquitin-conjugating enzyme E2C | 0.012 | ||
Atg12 | autophagy-related 12 (yeast) | 0.012 | ||
Mns1 | meiosis-specific nuclear structural protein 1 | 0.012 | ||
Kif2a | kinesin family member 2A | 0.012 | ||
Eea1 | early endosome antigen 1 | 0.012 | ||
Mtap1b | microtubule-associated protein 1B | 0.012 | ||
Chek1 | checkpoint kinase 1 homolog (S. pombe) | 0.012 | Human | |
Wee1 | WEE 1 homolog 1 (S. pombe) | 0.012 | Fly | |
Chst10 | carbohydrate sulfotransferase 10 | 0.012 | ||
Hmgb2 | high mobility group box 2 | 0.011 | ||
Cul5 | cullin 5 | 0.011 | ||
Vps4a | vacuolar protein sorting 4a (yeast) | 0.011 | ||
Smndc1 | survival motor neuron domain containing 1 | 0.011 | ||
Pcmt1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 | 0.011 | ||
Ttc33 | tetratricopeptide repeat domain 33 | 0.011 | ||
March6 | membrane-associated ring finger (C3HC4) 6 | 0.011 | ||
Sgk1 | serum/glucocorticoid regulated kinase 1 | 0.011 | ||
Eif5 | eukaryotic translation initiation factor 5 | 0.011 | ||
Blm | Bloom syndrome, RecQ helicase-like | 0.011 | ||
Sgol1 | shugoshin-like 1 (S. pombe) | 0.011 | ||
Golga4 | golgi autoantigen, golgin subfamily a, 4 | 0.011 | ||
Ptges3 | prostaglandin E synthase 3 (cytosolic) | 0.011 | ||
A630007B06Rik | RIKEN cDNA A630007B06 gene | 0.011 | ||
Cpeb4 | cytoplasmic polyadenylation element binding protein 4 | 0.011 | ||
Rad18 | RAD18 homolog (S. cerevisiae) | 0.011 | ||
Ppid | peptidylprolyl isomerase D (cyclophilin D) | 0.011 | ||
Vmn1r148 | vomeronasal 1 receptor 148 | 0.011 | ||
Tank | TRAF family member-associated Nf-kappa B activator | 0.011 | ||
Kctd9 | potassium channel tetramerisation domain containing 9 | 0.011 | ||
Dnaja1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.011 | ||
Cdca7 | cell division cycle associated 7 | 0.011 | ||
Hnrnpc | heterogeneous nuclear ribonucleoprotein C | 0.011 | ||
Rabgef1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.011 | ||
Sucla2 | succinate-Coenzyme A ligase, ADP-forming, beta subunit | 0.011 | ||
Gpcpd1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.011 | ||
4933406J08Rik | RIKEN cDNA 4933406J08 gene | 0.010 | ||
Lrr1 | leucine rich repeat protein 1 | 0.010 | ||
Rock2 | Rho-associated coiled-coil containing protein kinase 2 | 0.010 | ||
Ddx3x | DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked | 0.010 | ||
Kcna6 | potassium voltage-gated channel, shaker-related, subfamily, member 6 | 0.010 | ||
Rad51c | RAD51 homolog c (S. cerevisiae) | 0.010 | ||
Mtmr7 | myotubularin related protein 7 | 0.010 | ||
Cdc42 | cell division cycle 42 homolog (S. cerevisiae) | 0.010 | ||
Ell2 | elongation factor RNA polymerase II 2 | 0.010 | ||
Psrc1 | proline/serine-rich coiled-coil 1 | 0.010 | ||
Arf4 | ADP-ribosylation factor 4 | 0.010 | ||
Pnpla8 | patatin-like phospholipase domain containing 8 | 0.010 | ||
Usp1 | ubiquitin specific peptidase 1 | 0.010 | ||
Nedd4l | neural precursor cell expressed, developmentally down-regulated gene 4-like | 0.010 | ||
Lsm14a | LSM14 homolog A (SCD6, S. cerevisiae) | 0.010 |