IMP: Integrative Multi-species Prediction

Mus musculus

3 genes annotated in mouse

response to copper ion

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to copper ion"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "response to copper ion" (in gray)

Name	Description	Probability	Func Analog Organism
Mt2	metallothionein 2	0.678
Mt1	metallothionein 1	0.633
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.447
Cp	ceruloplasmin	0.253
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.153
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.120
Steap3	STEAP family member 3	0.109
Slc39a4	solute carrier family 39 (zinc transporter), member 4	0.094
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.085
Apoe	apolipoprotein E	0.074
Scp2	sterol carrier protein 2, liver	0.067
Atp6v0b	ATPase, H+ transporting, lysosomal V0 subunit B	0.067
Ccr2	chemokine (C-C motif) receptor 2	0.062
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.060
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.058
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.054
Slc31a1	solute carrier family 31, member 1	0.053	Zebrafish
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.052
Tlr4	toll-like receptor 4	0.048
Irf1	interferon regulatory factor 1	0.047
Hbb-b2	hemoglobin, beta adult minor chain	0.044
Bax	BCL2-associated X protein	0.044
Lox	lysyl oxidase	0.043
Fas	Fas (TNF receptor superfamily member 6)	0.043
Etfa	electron transferring flavoprotein, alpha polypeptide	0.037
Il1b	interleukin 1 beta	0.037
2010106G01Rik	RIKEN cDNA 2010106G01 gene	0.036
Aldh6a1	aldehyde dehydrogenase family 6, subfamily A1	0.034
Ccl2	chemokine (C-C motif) ligand 2	0.034
Cd44	CD44 antigen	0.034
Atp6v0c	ATPase, H+ transporting, lysosomal V0 subunit C	0.033
Myd88	myeloid differentiation primary response gene 88	0.033
Egfl7	EGF-like domain 7	0.033
Lrrc59	leucine rich repeat containing 59	0.032
Cyp2d26	cytochrome P450, family 2, subfamily d, polypeptide 26	0.032
Hmox1	heme oxygenase (decycling) 1	0.031
Kit	kit oncogene	0.030
Hsd17b4	hydroxysteroid (17-beta) dehydrogenase 4	0.030
Pklr	pyruvate kinase liver and red blood cell	0.030
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.029
Etfdh	electron transferring flavoprotein, dehydrogenase	0.028
Hfe	hemochromatosis	0.028
Idh1	isocitrate dehydrogenase 1 (NADP+), soluble	0.026
Lpin1	lipin 1	0.024
Cyb5	cytochrome b-5	0.024
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.023
Mmp9	matrix metallopeptidase 9	0.023
Chpt1	choline phosphotransferase 1	0.022
Hsdl2	hydroxysteroid dehydrogenase like 2	0.022
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.021
Grina	glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)	0.020
Spna1	spectrin alpha 1	0.020
Clu	clusterin	0.020
Vamp2	vesicle-associated membrane protein 2	0.020
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.020
Stx1a	syntaxin 1A (brain)	0.020
Wwtr1	WW domain containing transcription regulator 1	0.019
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.019
Prkch	protein kinase C, eta	0.019
Ccna2	cyclin A2	0.019
Tfrc	transferrin receptor	0.019
Phyh	phytanoyl-CoA hydroxylase	0.019
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.019
Atp7b	ATPase, Cu++ transporting, beta polypeptide	0.019	Human Mouse Rat
Hadh	hydroxyacyl-Coenzyme A dehydrogenase	0.018
Lyst	lysosomal trafficking regulator	0.018
Atp6ap1	ATPase, H+ transporting, lysosomal accessory protein 1	0.018
Fbxl5	F-box and leucine-rich repeat protein 5	0.017
Prnp	prion protein	0.017
Sgca	sarcoglycan, alpha (dystrophin-associated glycoprotein)	0.017
Nphs2	nephrosis 2 homolog, podocin (human)	0.017
Gabarap	gamma-aminobutyric acid receptor associated protein	0.017
Apoa2	apolipoprotein A-II	0.017
Gpr98	G protein-coupled receptor 98	0.017
Slc3a2	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2	0.017
Lyz2	lysozyme 2	0.017
Atox1	ATX1 (antioxidant protein 1) homolog 1 (yeast)	0.016
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.016
5730469M10Rik	RIKEN cDNA 5730469M10 gene	0.016
Tgfbr1	transforming growth factor, beta receptor I	0.016
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.016
Bcl3	B-cell leukemia/lymphoma 3	0.016
Gdnf	glial cell line derived neurotrophic factor	0.015
Cpt1a	carnitine palmitoyltransferase 1a, liver	0.015
Ephx2	epoxide hydrolase 2, cytoplasmic	0.015
Wbp2	WW domain binding protein 2	0.015
Serpind1	serine (or cysteine) peptidase inhibitor, clade D, member 1	0.015
Dvl3	dishevelled 3, dsh homolog (Drosophila)	0.015
Vhl	von Hippel-Lindau tumor suppressor	0.015
Napa	N-ethylmaleimide sensitive fusion protein attachment protein alpha	0.015
Ptpn23	protein tyrosine phosphatase, non-receptor type 23	0.015
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.014
Pcsk4	proprotein convertase subtilisin/kexin type 4	0.014
Alas2	aminolevulinic acid synthase 2, erythroid	0.014
Gc	group specific component	0.014
Fbp1	fructose bisphosphatase 1	0.014
Slc11a2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2	0.014
Lcn2	lipocalin 2	0.014
Il1r1	interleukin 1 receptor, type I	0.014
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.014
Prkci	protein kinase C, iota	0.014
Aco1	aconitase 1	0.014
Acad11	acyl-Coenzyme A dehydrogenase family, member 11	0.014
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.014
Itga3	integrin alpha 3	0.014
Ehd3	EH-domain containing 3	0.013
Mark4	MAP/microtubule affinity-regulating kinase 4	0.013
Nos1	nitric oxide synthase 1, neuronal	0.013
Lama5	laminin, alpha 5	0.013
Mut	methylmalonyl-Coenzyme A mutase	0.013
Apoa1	apolipoprotein A-I	0.013
Pld3	phospholipase D family, member 3	0.013
Il2rg	interleukin 2 receptor, gamma chain	0.013
Pxn	paxillin	0.013
Dctn2	dynactin 2	0.013
Nfkbib	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.013
Hadhb	hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit	0.013
Fam134a	family with sequence similarity 134, member A	0.013
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.013
Kif20a	kinesin family member 20A	0.013
Wt1	Wilms tumor 1 homolog	0.013
Col4a3	collagen, type IV, alpha 3	0.013
Pttg1ip	pituitary tumor-transforming 1 interacting protein	0.013
Ehhadh	enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase	0.013
Gck	glucokinase	0.012
Gbe1	glucan (1,4-alpha-), branching enzyme 1	0.012
Atp6v1b2	ATPase, H+ transporting, lysosomal V1 subunit B2	0.012
Itga1	integrin alpha 1	0.012
Pbk	PDZ binding kinase	0.012
Ccnb1	cyclin B1	0.012
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.012
Abcd3	ATP-binding cassette, sub-family D (ALD), member 3	0.012
Tgif1	TGFB-induced factor homeobox 1	0.012
Ldlr	low density lipoprotein receptor	0.012
Fbn1	fibrillin 1	0.012
Epor	erythropoietin receptor	0.012
Krtap5-1	keratin associated protein 5-1	0.012
Tbc1d20	TBC1 domain family, member 20	0.012
Ercc2	excision repair cross-complementing rodent repair deficiency, complementation group 2	0.012
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.012
Espn	espin	0.012
Oat	ornithine aminotransferase	0.012
Gsr	glutathione reductase	0.012
Birc3	baculoviral IAP repeat-containing 3	0.012
Abhd5	abhydrolase domain containing 5	0.012
BC031181	cDNA sequence BC031181	0.012
Ubc	ubiquitin C	0.012
Serpinf2	serine (or cysteine) peptidase inhibitor, clade F, member 2	0.012
Aff1	AF4/FMR2 family, member 1	0.012
Lgals3	lectin, galactose binding, soluble 3	0.011
Apoc4	apolipoprotein C-IV	0.011
Ambp	alpha 1 microglobulin/bikunin	0.011
Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.011
Hbb-b1	hemoglobin, beta adult major chain	0.011
Pou4f3	POU domain, class 4, transcription factor 3	0.011
Osmr	oncostatin M receptor	0.011
Gcgr	glucagon receptor	0.011
Stk4	serine/threonine kinase 4	0.011
Rasgrf2	RAS protein-specific guanine nucleotide-releasing factor 2	0.011
Acox1	acyl-Coenzyme A oxidase 1, palmitoyl	0.011
Gadd45g	growth arrest and DNA-damage-inducible 45 gamma	0.011
Slc18a2	solute carrier family 18 (vesicular monoamine), member 2	0.011
Plg	plasminogen	0.011
Klc2	kinesin light chain 2	0.011
Cbs	cystathionine beta-synthase	0.011
Lrrc8c	leucine rich repeat containing 8 family, member C	0.011
Clip2	CAP-GLY domain containing linker protein 2	0.011
Apoh	apolipoprotein H	0.011
Tnip2	TNFAIP3 interacting protein 2	0.011
Proz	protein Z, vitamin K-dependent plasma glycoprotein	0.011
Aqp8	aquaporin 8	0.011
Inhba	inhibin beta-A	0.011
Gclm	glutamate-cysteine ligase, modifier subunit	0.011
Decr1	2,4-dienoyl CoA reductase 1, mitochondrial	0.011
Flot1	flotillin 1	0.011
Traf6	TNF receptor-associated factor 6	0.011
4931406C07Rik	RIKEN cDNA 4931406C07 gene	0.011
Mavs	mitochondrial antiviral signaling protein	0.011
Hba-a2	hemoglobin alpha, adult chain 2	0.011
Asf1b	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	0.011
Procr	protein C receptor, endothelial	0.011
Rragc	Ras-related GTP binding C	0.011
Slc27a2	solute carrier family 27 (fatty acid transporter), member 2	0.011
Hibadh	3-hydroxyisobutyrate dehydrogenase	0.011
Vnn3	vanin 3	0.011
Smad3	MAD homolog 3 (Drosophila)	0.011
Cyp2c68	cytochrome P450, family 2, subfamily c, polypeptide 68	0.010
Fut8	fucosyltransferase 8	0.010
Abcb4	ATP-binding cassette, sub-family B (MDR/TAP), member 4	0.010
Vsig4	V-set and immunoglobulin domain containing 4	0.010
Gadd45b	growth arrest and DNA-damage-inducible 45 beta	0.010
Gyk	glycerol kinase	0.010
Casp9	caspase 9	0.010
Sdc4	syndecan 4	0.010
Rnasek	ribonuclease, RNase K	0.010
Socs3	suppressor of cytokine signaling 3	0.010
Sec14l2	SEC14-like 2 (S. cerevisiae)	0.010
Wsb2	WD repeat and SOCS box-containing 2	0.010
Lemd2	LEM domain containing 2	0.010
Chst3	carbohydrate (chondroitin 6/keratan) sulfotransferase 3	0.010
Gypa	glycophorin A	0.010
Cdhr5	cadherin-related family member 5	0.010
Acsl1	acyl-CoA synthetase long-chain family member 1	0.010
Il6st	interleukin 6 signal transducer	0.010
Beta-s	hemoglobin subunit beta-1-like	0.010
Lyve1	lymphatic vessel endothelial hyaluronan receptor 1	0.010