IMP
Process View
centromere complex assembly
The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "centromere complex assembly"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Ect2 | ect2 oncogene | 0.503 | ||
| Haus6 | HAUS augmin-like complex, subunit 6 | 0.419 | ||
| Dck | deoxycytidine kinase | 0.270 | ||
| Plk4 | polo-like kinase 4 (Drosophila) | 0.199 | ||
| Casp8ap2 | caspase 8 associated protein 2 | 0.183 | ||
| Smc2 | structural maintenance of chromosomes 2 | 0.164 | ||
| Smc4 | structural maintenance of chromosomes 4 | 0.138 | ||
| C330027C09Rik | RIKEN cDNA C330027C09 gene | 0.118 | ||
| Srsf7 | serine/arginine-rich splicing factor 7 | 0.111 | ||
| Trim59 | tripartite motif-containing 59 | 0.091 | ||
| Ezh2 | enhancer of zeste homolog 2 (Drosophila) | 0.079 | ||
| Tmpo | thymopoietin | 0.078 | ||
| Cenpk | centromere protein K | 0.075 | ||
| Mad2l1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.072 | ||
| Cdc6 | cell division cycle 6 homolog (S. cerevisiae) | 0.063 | ||
| Ncapg2 | non-SMC condensin II complex, subunit G2 | 0.063 | ||
| Srsf5 | serine/arginine-rich splicing factor 5 | 0.054 | ||
| Chek1 | checkpoint kinase 1 homolog (S. pombe) | 0.052 | ||
| Atad2 | ATPase family, AAA domain containing 2 | 0.044 | ||
| Rfc3 | replication factor C (activator 1) 3 | 0.043 | ||
| Cenpq | centromere protein Q | 0.040 | ||
| Dnmt3b | DNA methyltransferase 3B | 0.036 | ||
| 2610039C10Rik | RIKEN cDNA 2610039C10 gene | 0.034 | ||
| Bub1 | budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) | 0.033 | ||
| Eri2 | exoribonuclease 2 | 0.033 | ||
| 1110004F10Rik | RIKEN cDNA 1110004F10 gene | 0.030 | ||
| Siah1b | seven in absentia 1B | 0.030 | ||
| 5830433M19Rik | RIKEN cDNA 5830433M19 gene | 0.030 | ||
| Hmgb2 | high mobility group box 2 | 0.030 | ||
| Topbp1 | topoisomerase (DNA) II binding protein 1 | 0.027 | ||
| Slbp | stem-loop binding protein | 0.027 | ||
| Caprin1 | cell cycle associated protein 1 | 0.026 | ||
| Lin9 | lin-9 homolog (C. elegans) | 0.026 | ||
| Pacrgl | PARK2 co-regulated-like | 0.026 | ||
| Terf1 | telomeric repeat binding factor 1 | 0.025 | ||
| Dsn1 | DSN1, MIND kinetochore complex component, homolog (S. cerevisiae) | 0.025 | ||
| Stag1 | stromal antigen 1 | 0.025 | ||
| Eri1 | exoribonuclease 1 | 0.025 | ||
| Wsb1 | WD repeat and SOCS box-containing 1 | 0.024 | ||
| G2e3 | G2/M-phase specific E3 ubiquitin ligase | 0.023 | ||
| Stil | Scl/Tal1 interrupting locus | 0.023 | ||
| Adss | adenylosuccinate synthetase, non muscle | 0.022 | ||
| Dhx15 | DEAH (Asp-Glu-Ala-His) box polypeptide 15 | 0.021 | ||
| Rrm2 | ribonucleotide reductase M2 | 0.021 | ||
| Myef2 | myelin basic protein expression factor 2, repressor | 0.021 | ||
| Cklf | chemokine-like factor | 0.020 | ||
| Rbm26 | RNA binding motif protein 26 | 0.020 | ||
| Rad51ap1 | RAD51 associated protein 1 | 0.020 | ||
| Fmr1 | fragile X mental retardation syndrome 1 homolog | 0.019 | ||
| Racgap1 | Rac GTPase-activating protein 1 | 0.018 | ||
| Msh6 | mutS homolog 6 (E. coli) | 0.018 | ||
| Top2a | topoisomerase (DNA) II alpha | 0.017 | ||
| Zwilch | Zwilch, kinetochore associated, homolog (Drosophila) | 0.017 | ||
| Lrrc40 | leucine rich repeat containing 40 | 0.017 | ||
| BC016423 | cDNA sequence BC016423 | 0.017 | ||
| Ncaph | non-SMC condensin I complex, subunit H | 0.017 | ||
| Shcbp1 | Shc SH2-domain binding protein 1 | 0.016 | ||
| Ccne2 | cyclin E2 | 0.016 | ||
| Dr1 | down-regulator of transcription 1 | 0.016 | ||
| Cirbp | cold inducible RNA binding protein | 0.016 | ||
| Mki67 | antigen identified by monoclonal antibody Ki 67 | 0.016 | ||
| Rnf138 | ring finger protein 138 | 0.016 | ||
| Ccna2 | cyclin A2 | 0.015 | ||
| Pold3 | polymerase (DNA-directed), delta 3, accessory subunit | 0.015 | ||
| Cnot6 | CCR4-NOT transcription complex, subunit 6 | 0.015 | ||
| Depdc1a | DEP domain containing 1a | 0.015 | ||
| D030056L22Rik | RIKEN cDNA D030056L22 gene | 0.015 | ||
| Rad51 | RAD51 homolog (S. cerevisiae) | 0.014 | ||
| Ccnb2 | cyclin B2 | 0.014 | ||
| Cdc7 | cell division cycle 7 (S. cerevisiae) | 0.014 | ||
| Cenpl | centromere protein L | 0.013 | ||
| Etaa1 | Ewing's tumor-associated antigen 1 | 0.013 | ||
| Ythdc2 | YTH domain containing 2 | 0.013 | ||
| Trip13 | thyroid hormone receptor interactor 13 | 0.012 | ||
| Melk | maternal embryonic leucine zipper kinase | 0.012 | ||
| Cbx1 | chromobox homolog 1 (Drosophila HP1 beta) | 0.012 | ||
| Cdca7 | cell division cycle associated 7 | 0.012 | ||
| Actr3 | ARP3 actin-related protein 3 homolog (yeast) | 0.012 | ||
| Efcab7 | EF-hand calcium binding domain 7 | 0.012 | ||
| Pola1 | polymerase (DNA directed), alpha 1 | 0.012 | ||
| Ube2c | ubiquitin-conjugating enzyme E2C | 0.012 | ||
| Nup205 | nucleoporin 205 | 0.012 | ||
| Cenpa | centromere protein A | 0.012 | Human | |
| Pafah1b2 | platelet-activating factor acetylhydrolase, isoform 1b, subunit 2 | 0.011 | ||
| Dnmt3a | DNA methyltransferase 3A | 0.011 | ||
| Morc3 | microrchidia 3 | 0.011 | ||
| Dna2 | DNA replication helicase 2 homolog (yeast) | 0.011 | ||
| Cenpc1 | centromere protein C1 | 0.011 | Human Worm | |
| Rbl1 | retinoblastoma-like 1 (p107) | 0.011 | ||
| Suz12 | suppressor of zeste 12 homolog (Drosophila) | 0.011 | ||
| Hnrnpa2b1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.011 | ||
| Nek2 | NIMA (never in mitosis gene a)-related expressed kinase 2 | 0.011 | ||
| Nup50 | nucleoporin 50 | 0.011 | ||
| Rbbp8 | retinoblastoma binding protein 8 | 0.011 | ||
| Pnrc2 | proline-rich nuclear receptor coactivator 2 | 0.010 | ||
| Pdk3 | pyruvate dehydrogenase kinase, isoenzyme 3 | 0.010 | ||
| Srsf1 | serine/arginine-rich splicing factor 1 | 0.010 | ||
| Ino80c | INO80 complex subunit C | 0.010 |