IMP: Integrative Multi-species Prediction

Mus musculus

80 genes annotated in mouse

positive regulation of innate immune response

Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of innate immune response"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "positive regulation of innate immune response" (in gray)

Name	Description	Probability	Func Analog Organism
Myd88	myeloid differentiation primary response gene 88	1.000
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	1.000
Traf6	TNF receptor-associated factor 6	0.999	Mouse
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.999
Pten	phosphatase and tensin homolog	0.998
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.997	Human
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.996	Fly
Tlr4	toll-like receptor 4	0.995
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.994
Casp1	caspase 1	0.986	Fly
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.985	Fly
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.984
Axl	AXL receptor tyrosine kinase	0.979	Mouse
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.978
Slamf1	signaling lymphocytic activation molecule family member 1	0.967
Icos	inducible T-cell co-stimulator	0.955
Irf9	interferon regulatory factor 9	0.949	Mouse
Klra9	killer cell lectin-like receptor subfamily A, member 9	0.947
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.944
Trim21	tripartite motif-containing 21	0.938	Mouse
Tnf	tumor necrosis factor	0.928
Birc3	baculoviral IAP repeat-containing 3	0.924
Stat1	signal transducer and activator of transcription 1	0.906	Mouse
Cd180	CD180 antigen	0.891	Mouse
Ddx60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.882
Irf1	interferon regulatory factor 1	0.877
Trim30a	tripartite motif-containing 30A	0.874
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.871
Ifi203	interferon activated gene 203	0.853	Mouse
Ikbkg	inhibitor of kappaB kinase gamma	0.852
Parp14	poly (ADP-ribose) polymerase family, member 14	0.842
Chuk	conserved helix-loop-helix ubiquitous kinase	0.830	Mouse
Csf1	colony stimulating factor 1 (macrophage)	0.808
Ikbkb	inhibitor of kappaB kinase beta	0.759	Mouse
Pycard	PYD and CARD domain containing	0.757
Il1rn	interleukin 1 receptor antagonist	0.751
Stat3	signal transducer and activator of transcription 3	0.742	Mouse
Arrb2	arrestin, beta 2	0.736
Nlrp3	NLR family, pyrin domain containing 3	0.731	Mouse
Ncr1	natural cytotoxicity triggering receptor 1	0.723
Irf5	interferon regulatory factor 5	0.712	Mouse
Apoe	apolipoprotein E	0.710
Fasl	Fas ligand (TNF superfamily, member 6)	0.696
Pyhin1	pyrin and HIN domain family, member 1	0.682
Gbp7	guanylate binding protein 7	0.677
Gbp5	guanylate binding protein 5	0.666
Irf7	interferon regulatory factor 7	0.653
Gnrh1	gonadotropin releasing hormone 1	0.649
Esr1	estrogen receptor 1 (alpha)	0.637
Trim30d	tripartite motif-containing 30D	0.633	Human Mouse
Mapk14	mitogen-activated protein kinase 14	0.629
Adam12	a disintegrin and metallopeptidase domain 12 (meltrin alpha)	0.622	Mouse
Casp8	caspase 8	0.599
Lyz2	lysozyme 2	0.599
Il2rg	interleukin 2 receptor, gamma chain	0.598
Thra	thyroid hormone receptor alpha	0.597
Cd84	CD84 antigen	0.595
Mndal	myeloid nuclear differentiation antigen like	0.581
Ccl4	chemokine (C-C motif) ligand 4	0.570
Aim2	absent in melanoma 2	0.565
Gzmk	granzyme K	0.564
Pilrb1	paired immunoglobin-like type 2 receptor beta 1	0.558
Il10	interleukin 10	0.552
Ccr3	chemokine (C-C motif) receptor 3	0.542
Arrb1	arrestin, beta 1	0.528	Mouse
Clec4e	C-type lectin domain family 4, member e	0.527
Irak3	interleukin-1 receptor-associated kinase 3	0.526
Inpp5d	inositol polyphosphate-5-phosphatase D	0.521
Ifnar1	interferon (alpha and beta) receptor 1	0.520
Cd28	CD28 antigen	0.516
Gab1	growth factor receptor bound protein 2-associated protein 1	0.516
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.513
Rel	reticuloendotheliosis oncogene	0.513
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.511
Tapbp	TAP binding protein	0.504
Reg3g	regenerating islet-derived 3 gamma	0.502
Clec4n	C-type lectin domain family 4, member n	0.501
Irgm1	immunity-related GTPase family M member 1	0.498
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.497
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.494
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.489
Gzmb	granzyme B	0.484
Ltbr	lymphotoxin B receptor	0.481
Ifi44	interferon-induced protein 44	0.479
Dhx58	DEXH (Asp-Glu-X-His) box polypeptide 58	0.476
Stat2	signal transducer and activator of transcription 2	0.461	Mouse
Mnda	myeloid cell nuclear differentiation antigen	0.456	Human
Pax8	paired box gene 8	0.444
Ptprc	protein tyrosine phosphatase, receptor type, C	0.438
Grb2	growth factor receptor bound protein 2	0.433
Stat5a	signal transducer and activator of transcription 5A	0.432
Il2	interleukin 2	0.431
Ubd	ubiquitin D	0.430
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.429
Il1r1	interleukin 1 receptor, type I	0.423
Atf2	activating transcription factor 2	0.411
Slamf8	SLAM family member 8	0.404
Prnp	prion protein	0.400
Tlr8	toll-like receptor 8	0.396	Human Mouse
Cd44	CD44 antigen	0.396
Ikzf1	IKAROS family zinc finger 1	0.388
Il18rap	interleukin 18 receptor accessory protein	0.387
Unc93b1	unc-93 homolog B1 (C. elegans)	0.385
Sykb	spleen tyrosine kinase	0.381
Aoah	acyloxyacyl hydrolase	0.376
Cxcl10	chemokine (C-X-C motif) ligand 10	0.370
Tlr2	toll-like receptor 2	0.363
H2-Q7	histocompatibility 2, Q region locus 7	0.360
Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.359
Ccr6	chemokine (C-C motif) receptor 6	0.356
Il4	interleukin 4	0.355
Irak4	interleukin-1 receptor-associated kinase 4	0.346
Adam19	a disintegrin and metallopeptidase domain 19 (meltrin beta)	0.343	Mouse
Bcl3	B-cell leukemia/lymphoma 3	0.340	Mouse
Gbp3	guanylate binding protein 3	0.331
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.325
B2m	beta-2 microglobulin	0.313
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.309
Apobec3	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3	0.306
Adam17	a disintegrin and metallopeptidase domain 17	0.305	Mouse
Il4ra	interleukin 4 receptor, alpha	0.305
Uba7	ubiquitin-like modifier activating enzyme 7	0.304
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.300	Mouse
Ly9	lymphocyte antigen 9	0.298
Reg1	regenerating islet-derived 1	0.298	Mouse
Slfn2	schlafen 2	0.296
Irg1	immunoresponsive gene 1	0.296
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.293	Mouse
Tifa	TRAF-interacting protein with forkhead-associated domain	0.291
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.283	Mouse
Ccr2	chemokine (C-C motif) receptor 2	0.281
Duox2	dual oxidase 2	0.279
Socs1	suppressor of cytokine signaling 1	0.279
Cxcl13	chemokine (C-X-C motif) ligand 13	0.277
BC006779	cDNA sequence BC006779	0.277
Cxcl9	chemokine (C-X-C motif) ligand 9	0.276
Tyro3	TYRO3 protein tyrosine kinase 3	0.273
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.273
Il18r1	interleukin 18 receptor 1	0.270
Cd14	CD14 antigen	0.266
Tmem106a	transmembrane protein 106A	0.266
Gzma	granzyme A	0.264
Gbp2	guanylate binding protein 2	0.263
Slamf7	SLAM family member 7	0.260
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.255
Epsti1	epithelial stromal interaction 1 (breast)	0.255
Tor3a	torsin family 3, member A	0.251
Mcoln2	mucolipin 2	0.245
Cd4	CD4 antigen	0.241
Spna1	spectrin alpha 1	0.241
H2-DMb2	histocompatibility 2, class II, locus Mb2	0.239
Tap1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.238
Ccr9	chemokine (C-C motif) receptor 9	0.236
Reg3a	regenerating islet-derived 3 alpha	0.235	Mouse
Traf1	TNF receptor-associated factor 1	0.233	Mouse
Trim12a	tripartite motif-containing 12A	0.233	Human Mouse
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.233
BC013712	cDNA sequence BC013712	0.232
Ddx58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.231	Human Mouse
Tnfaip2	tumor necrosis factor, alpha-induced protein 2	0.229
Itgal	integrin alpha L	0.229
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.227
Trem3	triggering receptor expressed on myeloid cells 3	0.227
Blnk	B-cell linker	0.225
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.223	Mouse
Plcg2	phospholipase C, gamma 2	0.221
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.220	Mouse
Mmp8	matrix metallopeptidase 8	0.220	Mouse
Icam1	intercellular adhesion molecule 1	0.220
Clec4d	C-type lectin domain family 4, member d	0.219
Stat6	signal transducer and activator of transcription 6	0.216	Mouse
Cenpj	centromere protein J	0.215
Emr4	EGF-like module containing, mucin-like, hormone receptor-like sequence 4	0.215
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.213
H2-M3	histocompatibility 2, M region locus 3	0.213
Il7r	interleukin 7 receptor	0.211
Inhba	inhibin beta-A	0.206
Siglece	sialic acid binding Ig-like lectin E	0.203
Spib	Spi-B transcription factor (Spi-1/PU.1 related)	0.203
Pdcd1lg2	programmed cell death 1 ligand 2	0.201	Mouse
AW112010	expressed sequence AW112010	0.200
Pou2af1	POU domain, class 2, associating factor 1	0.200
Blk	B lymphoid kinase	0.197	Mouse
Il6	interleukin 6	0.197
Xcl1	chemokine (C motif) ligand 1	0.196
Ms4a1	membrane-spanning 4-domains, subfamily A, member 1	0.196
Itga4	integrin alpha 4	0.195
Cxcl2	chemokine (C-X-C motif) ligand 2	0.195
Pik3ap1	phosphoinositide-3-kinase adaptor protein 1	0.195
Stat5b	signal transducer and activator of transcription 5B	0.193
Mmp13	matrix metallopeptidase 13	0.192	Mouse
Hgf	hepatocyte growth factor	0.192
Traf3ip2	TRAF3 interacting protein 2	0.191
Bglap	bone gamma carboxyglutamate protein	0.190
Il1b	interleukin 1 beta	0.190
Samhd1	SAM domain and HD domain, 1	0.188
Oasl2	2'-5' oligoadenylate synthetase-like 2	0.187
Il2ra	interleukin 2 receptor, alpha chain	0.185
Tirap	toll-interleukin 1 receptor (TIR) domain-containing adaptor protein	0.183
Ly75	lymphocyte antigen 75	0.183
Tnfsf10	tumor necrosis factor (ligand) superfamily, member 10	0.182
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.178
Tgfbr2	transforming growth factor, beta receptor II	0.178
Foxp3	forkhead box P3	0.176
H2-Q6	histocompatibility 2, Q region locus 6	0.176
Ptk2	PTK2 protein tyrosine kinase 2	0.176
Parp10	poly (ADP-ribose) polymerase family, member 10	0.176
Cyld	cylindromatosis (turban tumor syndrome)	0.175
Timp1	tissue inhibitor of metalloproteinase 1	0.175
Mefv	Mediterranean fever	0.171
Irgm2	immunity-related GTPase family M member 2	0.170
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.170
Slc5a4a	solute carrier family 5, member 4a	0.169
Prf1	perforin 1 (pore forming protein)	0.168
Ncoa6	nuclear receptor coactivator 6	0.168
Tlr5	toll-like receptor 5	0.167	Human Mouse
Stx11	syntaxin 11	0.167
Ciita	class II transactivator	0.165
Mavs	mitochondrial antiviral signaling protein	0.165
Zbp1	Z-DNA binding protein 1	0.165
Slc7a11	solute carrier family 7 (cationic amino acid transporter, y+ system), member 11	0.163
Cbl	Casitas B-lineage lymphoma	0.163
Prlr	prolactin receptor	0.162
Src	Rous sarcoma oncogene	0.161	Mouse
Sharpin	SHANK-associated RH domain interacting protein	0.159
Slamf6	SLAM family member 6	0.156
Il1a	interleukin 1 alpha	0.155
Ptk2b	PTK2 protein tyrosine kinase 2 beta	0.155
AI607873	expressed sequence AI607873	0.155
Msr1	macrophage scavenger receptor 1	0.154
Il15	interleukin 15	0.154
Prdm1	PR domain containing 1, with ZNF domain	0.154
Il2rb	interleukin 2 receptor, beta chain	0.151
Ccl5	chemokine (C-C motif) ligand 5	0.151
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.150
Cdh11	cadherin 11	0.150
C1qtnf1	C1q and tumor necrosis factor related protein 1	0.150
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.149
Trim34a	tripartite motif-containing 34A	0.149	Mouse
Klrb1a	killer cell lectin-like receptor subfamily B member 1A	0.148	Mouse
P2ry10	purinergic receptor P2Y, G-protein coupled 10	0.148	Mouse
Klrc1	killer cell lectin-like receptor subfamily C, member 1	0.147	Mouse
Itgax	integrin alpha X	0.147
Cfh	complement component factor h	0.146
Naip1	NLR family, apoptosis inhibitory protein 1	0.145
Cybb	cytochrome b-245, beta polypeptide	0.144
Cd96	CD96 antigen	0.144
Igf1	insulin-like growth factor 1	0.142
Prkce	protein kinase C, epsilon	0.140
Fpr2	formyl peptide receptor 2	0.140
Fyn	Fyn proto-oncogene	0.139	Mouse
Cd33	CD33 antigen	0.138
Oasl1	2'-5' oligoadenylate synthetase-like 1	0.137
Pxn	paxillin	0.137
Ngp	neutrophilic granule protein	0.137
Ifnar2	interferon (alpha and beta) receptor 2	0.136
Serpinb7	serine (or cysteine) peptidase inhibitor, clade B, member 7	0.136
Ripk2	receptor (TNFRSF)-interacting serine-threonine kinase 2	0.135
Gata3	GATA binding protein 3	0.135
Tnfrsf11b	tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)	0.134
Sfn	stratifin	0.134
2010106G01Rik	RIKEN cDNA 2010106G01 gene	0.133
Naip6	NLR family, apoptosis inhibitory protein 6	0.131
Gm12185	predicted gene 12185	0.131
C3	complement component 3	0.131
Slfn1	schlafen 1	0.130
1810030J14Rik	RIKEN cDNA 1810030J14 gene	0.130
Ms4a4b	membrane-spanning 4-domains, subfamily A, member 4B	0.130
Psmb10	proteasome (prosome, macropain) subunit, beta type 10	0.129
Myo1g	myosin IG	0.129
Herc6	hect domain and RLD 6	0.126
Ticam1	toll-like receptor adaptor molecule 1	0.125
Ros1	Ros1 proto-oncogene	0.124
Reg3b	regenerating islet-derived 3 beta	0.124	Mouse
Tlr6	toll-like receptor 6	0.123	Mouse
Batf	basic leucine zipper transcription factor, ATF-like	0.123
Tbk1	TANK-binding kinase 1	0.123
Nfkbie	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.122	Mouse
Vasp	vasodilator-stimulated phosphoprotein	0.122
Ghr	growth hormone receptor	0.122
Plagl2	pleiomorphic adenoma gene-like 2	0.121
Apobec1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	0.119
Kmo	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.119
Lcp2	lymphocyte cytosolic protein 2	0.118
H2-Eb1	histocompatibility 2, class II antigen E beta	0.118
Psmb8	proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)	0.118
Fpr1	formyl peptide receptor 1	0.118
Mib1	mindbomb homolog 1 (Drosophila)	0.118
Fpr3	formyl peptide receptor 3	0.118
Ctsw	cathepsin W	0.117
Glrp1	glutamine repeat protein 1	0.116
Ccr7	chemokine (C-C motif) receptor 7	0.116
Plaur	plasminogen activator, urokinase receptor	0.115
Lpxn	leupaxin	0.115
Klra8	killer cell lectin-like receptor, subfamily A, member 8	0.114
Mertk	c-mer proto-oncogene tyrosine kinase	0.112	Mouse
Mx1	myxovirus (influenza virus) resistance 1	0.112
Cxcr6	chemokine (C-X-C motif) receptor 6	0.111
Abcg3	ATP-binding cassette, sub-family G (WHITE), member 3	0.111
Lamp2	lysosomal-associated membrane protein 2	0.111
Oas3	2'-5' oligoadenylate synthetase 3	0.110
S1pr2	sphingosine-1-phosphate receptor 2	0.109
Clnk	cytokine-dependent hematopoietic cell linker	0.109
Hnf4g	hepatocyte nuclear factor 4, gamma	0.109
Nr1h3	nuclear receptor subfamily 1, group H, member 3	0.109	Human
Fcgr4	Fc receptor, IgG, low affinity IV	0.109
Mmp12	matrix metallopeptidase 12	0.109	Mouse
Pion	pigeon homolog (Drosophila)	0.108
Olfr480	olfactory receptor 480	0.108
Saa4	serum amyloid A 4	0.108
Klrb1c	killer cell lectin-like receptor subfamily B member 1C	0.107
Il1f9	interleukin 1 family, member 9	0.105
Bex6	brain expressed gene 6	0.105
Rasa4	RAS p21 protein activator 4	0.104
Mlkl	mixed lineage kinase domain-like	0.104
Gm885	predicted gene 885	0.104
Ifi47	interferon gamma inducible protein 47	0.104
C3ar1	complement component 3a receptor 1	0.103
Ccr4	chemokine (C-C motif) receptor 4	0.103
Rag1	recombination activating gene 1	0.103
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.102
Pds5b	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.102
Hspa9	heat shock protein 9	0.100
Cysltr1	cysteinyl leukotriene receptor 1	0.100	Mouse
Nlrc5	NLR family, CARD domain containing 5	0.100
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.100
Prkcd	protein kinase C, delta	0.099
Shisa5	shisa homolog 5 (Xenopus laevis)	0.099
Cytip	cytohesin 1 interacting protein	0.098
Egr2	early growth response 2	0.098
Runx1	runt related transcription factor 1	0.098
Cyp4v3	cytochrome P450, family 4, subfamily v, polypeptide 3	0.096
Fam26f	family with sequence similarity 26, member F	0.096
Trim5	tripartite motif-containing 5	0.095	Human Mouse
Cd300lb	CD300 antigen like family member B	0.095
Irak1	interleukin-1 receptor-associated kinase 1	0.094
Ptpre	protein tyrosine phosphatase, receptor type, E	0.094
Gm6377	predicted gene 6377	0.094
Slpi	secretory leukocyte peptidase inhibitor	0.093
Stat4	signal transducer and activator of transcription 4	0.093	Mouse
Ltbp2	latent transforming growth factor beta binding protein 2	0.093
Lair1	leukocyte-associated Ig-like receptor 1	0.093
Lck	lymphocyte protein tyrosine kinase	0.093	Mouse
Plcd1	phospholipase C, delta 1	0.092
Klra5	killer cell lectin-like receptor, subfamily A, member 5	0.092	Mouse
Rnase4	ribonuclease, RNase A family 4	0.092
Gpr18	G protein-coupled receptor 18	0.092
Klrb1f	killer cell lectin-like receptor subfamily B member 1F	0.092	Mouse
Tnfsf9	tumor necrosis factor (ligand) superfamily, member 9	0.092
Zg16	zymogen granule protein 16	0.091
Tapbpl	TAP binding protein-like	0.091
5430427O19Rik	RIKEN cDNA 5430427O19 gene	0.091
Tab2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.091
Bcl2a1d	B-cell leukemia/lymphoma 2 related protein A1d	0.091
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.091
Trafd1	TRAF type zinc finger domain containing 1	0.091
Sulf2	sulfatase 2	0.091
Il10ra	interleukin 10 receptor, alpha	0.091
Rgs1	regulator of G-protein signaling 1	0.091
Traf2	TNF receptor-associated factor 2	0.091	Mouse
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.090
Itgae	integrin alpha E, epithelial-associated	0.090
Tlr1	toll-like receptor 1	0.090	Mouse
Gcm1	glial cells missing homolog 1 (Drosophila)	0.090
Pla2g2d	phospholipase A2, group IID	0.089
Areg	amphiregulin	0.089
Sbpl	spermine binding protein-like	0.089
Slfn8	schlafen 8	0.089
Gsdmd	gasdermin D	0.088
C1ra	complement component 1, r subcomponent A	0.088
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.088
Dtx3l	deltex 3-like (Drosophila)	0.088
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.088
Clock	circadian locomotor output cycles kaput	0.087
Gda	guanine deaminase	0.086
Cd72	CD72 antigen	0.086
Clec2i	C-type lectin domain family 2, member i	0.085
Allc	allantoicase	0.085
Fas	Fas (TNF receptor superfamily member 6)	0.085
Ncor1	nuclear receptor co-repressor 1	0.085
Lcn4	lipocalin 4	0.085
Zc3h12d	zinc finger CCCH type containing 12D	0.085
Irf4	interferon regulatory factor 4	0.085
Cd40lg	CD40 ligand	0.085
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.084	Mouse
Fam111a	family with sequence similarity 111, member A	0.084
Runx2	runt related transcription factor 2	0.083
Itk	IL2-inducible T-cell kinase	0.082
Pydc4	pyrin domain containing 4	0.082
Il17ra	interleukin 17 receptor A	0.082
Niacr1	niacin receptor 1	0.081
Cd244	CD244 natural killer cell receptor 2B4	0.081
Serpinb9	serine (or cysteine) peptidase inhibitor, clade B, member 9	0.081
Hif1a	hypoxia inducible factor 1, alpha subunit	0.080
Cd7	CD7 antigen	0.080
Cd83	CD83 antigen	0.080
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.080
Fcrla	Fc receptor-like A	0.080
Zfp362	zinc finger protein 362	0.080
Sfpi1	SFFV proviral integration 1	0.080
Steap4	STEAP family member 4	0.079
Gpr35	G protein-coupled receptor 35	0.079
Socs3	suppressor of cytokine signaling 3	0.079
Stap1	signal transducing adaptor family member 1	0.078
Smad4	MAD homolog 4 (Drosophila)	0.078
Cd80	CD80 antigen	0.078
Ccl2	chemokine (C-C motif) ligand 2	0.078
Rnase1	ribonuclease, RNase A family, 1 (pancreatic)	0.077
Mmp3	matrix metallopeptidase 3	0.077	Mouse
Oas1b	2'-5' oligoadenylate synthetase 1B	0.077
Sap18	Sin3-associated polypeptide 18	0.077
Cxcl16	chemokine (C-X-C motif) ligand 16	0.077
Samd9l	sterile alpha motif domain containing 9-like	0.077
Ms4a7	membrane-spanning 4-domains, subfamily A, member 7	0.076
Slc12a6	solute carrier family 12, member 6	0.076
Col10a1	collagen, type X, alpha 1	0.076
Prg2	proteoglycan 2, bone marrow	0.076
Sp100	nuclear antigen Sp100	0.075
Cd47	CD47 antigen (Rh-related antigen, integrin-associated signal transducer)	0.075
Iigp1	interferon inducible GTPase 1	0.075
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.075
2210010C04Rik	RIKEN cDNA 2210010C04 gene	0.075
Chi3l3	chitinase 3-like 3	0.074
Mtap2	microtubule-associated protein 2	0.074
Casp12	caspase 12	0.074	Fly
Plau	plasminogen activator, urokinase	0.073
Slfn4	schlafen 4	0.073
Trem1	triggering receptor expressed on myeloid cells 1	0.073
Ifng	interferon gamma	0.073
Ndufaf4	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4	0.073
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.072
Hoxa10	homeobox A10	0.072
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.072
Pilra	paired immunoglobin-like type 2 receptor alpha	0.072
Prss30	protease, serine, 30	0.072
P2ry13	purinergic receptor P2Y, G-protein coupled 13	0.072
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.072
Pml	promyelocytic leukemia	0.072
Ctnnb1	catenin (cadherin associated protein), beta 1	0.071
Etv6	ets variant gene 6 (TEL oncogene)	0.071
Gpr33	G protein-coupled receptor 33	0.071
Lipa	lysosomal acid lipase A	0.071
Adamdec1	ADAM-like, decysin 1	0.071	Mouse
Defa-rs1	defensin, alpha, related sequence 1	0.071
Flt3	FMS-like tyrosine kinase 3	0.071
Dub1	deubiquitinating enzyme 1	0.071
Klra3	killer cell lectin-like receptor, subfamily A, member 3	0.071	Mouse
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.070
Ccl20	chemokine (C-C motif) ligand 20	0.070
Clec7a	C-type lectin domain family 7, member a	0.069
Ggt5	gamma-glutamyltransferase 5	0.069
Prap1	proline-rich acidic protein 1	0.069
Ikzf3	IKAROS family zinc finger 3	0.069
Nmur2	neuromedin U receptor 2	0.069
Fcer1a	Fc receptor, IgE, high affinity I, alpha polypeptide	0.069
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.069
Parp9	poly (ADP-ribose) polymerase family, member 9	0.069
A630033H20Rik	RIKEN cDNA A630033H20 gene	0.068
Kynu	kynureninase (L-kynurenine hydrolase)	0.068
Ctsh	cathepsin H	0.068
Ncf1	neutrophil cytosolic factor 1	0.067
Gm10229	predicted gene 10229	0.067
Abcg1	ATP-binding cassette, sub-family G (WHITE), member 1	0.067
Rnf31	ring finger protein 31	0.067
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.067
Pcdh12	protocadherin 12	0.067
Mllt4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.066
Itga5	integrin alpha 5 (fibronectin receptor alpha)	0.066
Klre1	killer cell lectin-like receptor family E member 1	0.066
Rnase6	ribonuclease, RNase A family, 6	0.065
Scgb3a1	secretoglobin, family 3A, member 1	0.065
Btg4	B-cell translocation gene 4	0.065
Sell	selectin, lymphocyte	0.065
Trim25	tripartite motif-containing 25	0.065
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.065
Arap1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1	0.064
Cd22	CD22 antigen	0.064
Cmpk2	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial	0.063
Ifi204	interferon activated gene 204	0.063	Human
Cd274	CD274 antigen	0.063	Mouse
Il21r	interleukin 21 receptor	0.063
Epha2	Eph receptor A2	0.063
Chi3l1	chitinase 3-like 1	0.063
Alox15	arachidonate 15-lipoxygenase	0.062
Pvrl2	poliovirus receptor-related 2	0.062	Human
Slc40a1	solute carrier family 40 (iron-regulated transporter), member 1	0.062
Tnfrsf13c	tumor necrosis factor receptor superfamily, member 13c	0.062
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.062
Fpr-rs4	formyl peptide receptor, related sequence 4	0.062
Hsh2d	hematopoietic SH2 domain containing	0.062
Bmp1	bone morphogenetic protein 1	0.062
5430435G22Rik	RIKEN cDNA 5430435G22 gene	0.062
Notch2	Notch gene homolog 2 (Drosophila)	0.061
Galnt3	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3	0.061
Il24	interleukin 24	0.061
1810033B17Rik	RIKEN cDNA 1810033B17 gene	0.061
Tcirg1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3	0.061
Jak2	Janus kinase 2	0.060
Atr	ataxia telangiectasia and Rad3 related	0.060
Igsf6	immunoglobulin superfamily, member 6	0.060
Hsd17b3	hydroxysteroid (17-beta) dehydrogenase 3	0.060
Rarg	retinoic acid receptor, gamma	0.060
Ptger2	prostaglandin E receptor 2 (subtype EP2)	0.060
Itgb3	integrin beta 3	0.059
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.059
2210415F13Rik	RIKEN cDNA 2210415F13 gene	0.059
Frk	fyn-related kinase	0.059	Mouse
Xcr1	chemokine (C motif) receptor 1	0.059
Rsad2	radical S-adenosyl methionine domain containing 2	0.058
Il12b	interleukin 12b	0.058
9930023K05Rik	RIKEN cDNA 9930023K05 gene	0.058
Sftpd	surfactant associated protein D	0.058
Irf8	interferon regulatory factor 8	0.058	Mouse
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.058	Mouse
Ikbke	inhibitor of kappaB kinase epsilon	0.058	Mouse
Il1r2	interleukin 1 receptor, type II	0.057
Ctsb	cathepsin B	0.057
Angptl4	angiopoietin-like 4	0.057
Tfam	transcription factor A, mitochondrial	0.057
Il15ra	interleukin 15 receptor, alpha chain	0.057
Gucy2c	guanylate cyclase 2c	0.057
Kcnu1	potassium channel, subfamily U, member 1	0.057
Ear2	eosinophil-associated, ribonuclease A family, member 2	0.056
Grm1	glutamate receptor, metabotropic 1	0.056
Reg2	regenerating islet-derived 2	0.056	Mouse
Cdcp1	CUB domain containing protein 1	0.056
Tlr7	toll-like receptor 7	0.056
Tmem173	transmembrane protein 173	0.056
Zc3h12a	zinc finger CCCH type containing 12A	0.055
Ctsc	cathepsin C	0.055
Treml4	triggering receptor expressed on myeloid cells-like 4	0.055
Stom	stomatin	0.055
Plod3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3	0.055
Mthfs	5, 10-methenyltetrahydrofolate synthetase	0.055
Serpina5	serine (or cysteine) peptidase inhibitor, clade A, member 5	0.055
Cnp	2',3'-cyclic nucleotide 3' phosphodiesterase	0.055
Ly6e	lymphocyte antigen 6 complex, locus E	0.055
Csprs	component of Sp100-rs	0.055
Dmbt1	deleted in malignant brain tumors 1	0.055
Olfr65	olfactory receptor 65	0.055
AA408251	expressed sequence AA408251	0.055
Psap	prosaposin	0.055
Rc3h1	RING CCCH (C3H) domains 1	0.054
Rtp4	receptor transporter protein 4	0.054
Gns	glucosamine (N-acetyl)-6-sulfatase	0.054
Ooep	oocyte expressed protein homolog (dog)	0.054
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.054
Ar	androgen receptor	0.053
Ccl22	chemokine (C-C motif) ligand 22	0.053
Gfi1	growth factor independent 1	0.053
Nckap1l	NCK associated protein 1 like	0.053
D14Ertd668e	DNA segment, Chr 14, ERATO Doi 668, expressed	0.053
Gp2	glycoprotein 2 (zymogen granule membrane)	0.053
Usp18	ubiquitin specific peptidase 18	0.053
Tcra	T-cell receptor alpha chain	0.052
Akna	AT-hook transcription factor	0.052
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.052
Cd5	CD5 antigen	0.052
Dnm1	dynamin 1	0.052
H2-Q8	histocompatibility 2, Q region locus 8	0.052
Pbsn	probasin	0.052
Adam2	a disintegrin and metallopeptidase domain 2	0.052	Mouse
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.051
Trpm2	transient receptor potential cation channel, subfamily M, member 2	0.051
Npr2	natriuretic peptide receptor 2	0.051
Ms4a6d	membrane-spanning 4-domains, subfamily A, member 6D	0.051
March1	membrane-associated ring finger (C3HC4) 1	0.051
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.051
Pias3	protein inhibitor of activated STAT 3	0.051	Fly
Vmn1r65	vomeronasal 1 receptor 65	0.051
Mknk2	MAP kinase-interacting serine/threonine kinase 2	0.051
Tgm2	transglutaminase 2, C polypeptide	0.051
Klra17	killer cell lectin-like receptor, subfamily A, member 17	0.051	Mouse
Lat2	linker for activation of T cells family, member 2	0.051
Jup	junction plakoglobin	0.051
Zfp740	zinc finger protein 740	0.050
Gch1	GTP cyclohydrolase 1	0.050
Idua	iduronidase, alpha-L-	0.050
Cxcr3	chemokine (C-X-C motif) receptor 3	0.050
Pla2g2e	phospholipase A2, group IIE	0.050
Il5ra	interleukin 5 receptor, alpha	0.050
Gpa33	glycoprotein A33 (transmembrane)	0.050
Igtp	interferon gamma induced GTPase	0.050
9030625A04Rik	RIKEN cDNA 9030625A04 gene	0.050
4933425L06Rik	RIKEN cDNA 4933425L06 gene	0.050
Lrp10	low-density lipoprotein receptor-related protein 10	0.050
Cidec	cell death-inducing DFFA-like effector c	0.049
Cd86	CD86 antigen	0.049
Lcp1	lymphocyte cytosolic protein 1	0.049
Map3k3	mitogen-activated protein kinase kinase kinase 3	0.049
Catsper1	cation channel, sperm associated 1	0.049
Cd69	CD69 antigen	0.049	Mouse
Slc13a2	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2	0.048
Mvp	major vault protein	0.048
Traf3	TNF receptor-associated factor 3	0.048
Casp7	caspase 7	0.048
Sh2d1b2	SH2 domain protein 1B2	0.048
Cd209d	CD209d antigen	0.048
Ireb2	iron responsive element binding protein 2	0.048
Kcnk13	potassium channel, subfamily K, member 13	0.048
Fmo4	flavin containing monooxygenase 4	0.048
Cd247	CD247 antigen	0.048
Jak3	Janus kinase 3	0.048
Il18	interleukin 18	0.048
C78344	expressed sequence C78344	0.048
Tnfsf13b	tumor necrosis factor (ligand) superfamily, member 13b	0.047
Tll1	tolloid-like	0.047
Cd40	CD40 antigen	0.047	Zebrafish
Fbn1	fibrillin 1	0.047
Cma1	chymase 1, mast cell	0.047
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.046
Ddr2	discoidin domain receptor family, member 2	0.046
Faim3	Fas apoptotic inhibitory molecule 3	0.046
Sh2d2a	SH2 domain protein 2A	0.046
Serpina3g	serine (or cysteine) peptidase inhibitor, clade A, member 3G	0.046
Cd5l	CD5 antigen-like	0.046
Was	Wiskott-Aldrich syndrome homolog (human)	0.046
2010003K11Rik	RIKEN cDNA 2010003K11 gene	0.046
Gbp1	guanylate binding protein 1	0.046
Batf2	basic leucine zipper transcription factor, ATF-like 2	0.046
Apobr	apolipoprotein B receptor	0.046
Ms4a8a	membrane-spanning 4-domains, subfamily A, member 8A	0.046
St6galnac1	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1	0.046
Rhog	ras homolog gene family, member G	0.045
Asprv1	aspartic peptidase, retroviral-like 1	0.045
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.045
Pkd1	polycystic kidney disease 1 homolog	0.045
Tshb	thyroid stimulating hormone, beta subunit	0.045
Reg3d	regenerating islet-derived 3 delta	0.045	Mouse
Klra12	killer cell lectin-like receptor subfamily A, member 12	0.045
Nhej1	nonhomologous end-joining factor 1	0.045
Zbtb7b	zinc finger and BTB domain containing 7B	0.045
Ms4a6c	membrane-spanning 4-domains, subfamily A, member 6C	0.045
Tex19.2	testis expressed gene 19.2	0.045
Cmklr1	chemokine-like receptor 1	0.045
Rnf135	ring finger protein 135	0.045
Selp	selectin, platelet	0.045
H2-DMa	histocompatibility 2, class II, locus DMa	0.044
Xaf1	XIAP associated factor 1	0.044
St8sia4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.044
Ly96	lymphocyte antigen 96	0.044	Human
Ccr1	chemokine (C-C motif) receptor 1	0.044
Myf5	myogenic factor 5	0.044
Tnks1bp1	tankyrase 1 binding protein 1	0.044
Fcgr1	Fc receptor, IgG, high affinity I	0.044
Nmi	N-myc (and STAT) interactor	0.044
Cela3b	chymotrypsin-like elastase family, member 3B	0.044
P2ry12	purinergic receptor P2Y, G-protein coupled 12	0.044
Rara	retinoic acid receptor, alpha	0.044
Slc15a3	solute carrier family 15, member 3	0.044
Lrp1	low density lipoprotein receptor-related protein 1	0.044
Tlr13	toll-like receptor 13	0.044
Tmc2	transmembrane channel-like gene family 2	0.044
Serpina3c	serine (or cysteine) peptidase inhibitor, clade A, member 3C	0.044
Prrx1	paired related homeobox 1	0.044
Ly6i	lymphocyte antigen 6 complex, locus I	0.044
4833422F24Rik	RIKEN cDNA 4833422F24 gene	0.043
Sap25	sin3 associated polypeptide	0.043
Has2	hyaluronan synthase 2	0.043
Art2a-ps	ADP-ribosyltransferase 2a, pseudogene	0.043
Junb	Jun-B oncogene	0.043
Slc34a2	solute carrier family 34 (sodium phosphate), member 2	0.043
Ephb2	Eph receptor B2	0.043
Tcf7	transcription factor 7, T-cell specific	0.043
Hspa1b	heat shock protein 1B	0.043
Adap2	ArfGAP with dual PH domains 2	0.043
Ttc7	tetratricopeptide repeat domain 7	0.043
Azi2	5-azacytidine induced gene 2	0.043
Sult1c1	sulfotransferase family, cytosolic, 1C, member 1	0.043
Ccl7	chemokine (C-C motif) ligand 7	0.043
Ikbip	IKBKB interacting protein	0.042
Mrpl3	mitochondrial ribosomal protein L3	0.042
Spink4	serine peptidase inhibitor, Kazal type 4	0.042
Camp	cathelicidin antimicrobial peptide	0.042
Plbd2	phospholipase B domain containing 2	0.042
Dnase1l3	deoxyribonuclease 1-like 3	0.042
Mapk1	mitogen-activated protein kinase 1	0.042
Aicda	activation-induced cytidine deaminase	0.042
Sh2d1b1	SH2 domain protein 1B1	0.042
Cd300a	CD300A antigen	0.041	Mouse
Nfatc1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.041
Plbd1	phospholipase B domain containing 1	0.041
Amhr2	anti-Mullerian hormone type 2 receptor	0.041
Ltb	lymphotoxin B	0.041
Kiss1	KiSS-1 metastasis-suppressor	0.041
Tgtp2	T-cell specific GTPase 2	0.041
Cxcr5	chemokine (C-X-C motif) receptor 5	0.041
Vwa5a	von Willebrand factor A domain containing 5A	0.041
Serpini2	serine (or cysteine) peptidase inhibitor, clade I, member 2	0.041
E330016A19Rik	RIKEN cDNA E330016A19 gene	0.041
Tff2	trefoil factor 2 (spasmolytic protein 1)	0.041
Il6st	interleukin 6 signal transducer	0.041
Plek	pleckstrin	0.041
Actl7a	actin-like 7a	0.041
Htr2b	5-hydroxytryptamine (serotonin) receptor 2B	0.041
Ctsl	cathepsin L	0.040
Gbp6	guanylate binding protein 6	0.040
Leprel2	leprecan-like 2	0.040
Ptk6	PTK6 protein tyrosine kinase 6	0.040	Mouse
Stk10	serine/threonine kinase 10	0.040
Ctrc	chymotrypsin C (caldecrin)	0.040
Tnfsf8	tumor necrosis factor (ligand) superfamily, member 8	0.040
Gzmc	granzyme C	0.040
Angel2	angel homolog 2 (Drosophila)	0.040
Cd1d1	CD1d1 antigen	0.040
Osmr	oncostatin M receptor	0.040
Xdh	xanthine dehydrogenase	0.040
Bcl6	B-cell leukemia/lymphoma 6	0.040
Cdkn2d	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	0.040
Mdm4	transformed mouse 3T3 cell double minute 4	0.040
Tank	TRAF family member-associated Nf-kappa B activator	0.040
Mgl2	macrophage galactose N-acetyl-galactosamine specific lectin 2	0.039
Tlr11	toll-like receptor 11	0.039	Mouse
Zc3hav1	zinc finger CCCH type, antiviral 1	0.039	Human
Ifih1	interferon induced with helicase C domain 1	0.039	Mouse
Gpr84	G protein-coupled receptor 84	0.039
Prss44	protease, serine, 44	0.039
Il10rb	interleukin 10 receptor, beta	0.039
Itsn1	intersectin 1 (SH3 domain protein 1A)	0.039
Ifit3	interferon-induced protein with tetratricopeptide repeats 3	0.039
Star	steroidogenic acute regulatory protein	0.039
Tm4sf5	transmembrane 4 superfamily member 5	0.039
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.039
Tnip1	TNFAIP3 interacting protein 1	0.039
Kctd17	potassium channel tetramerisation domain containing 17	0.039
Dock10	dedicator of cytokinesis 10	0.039
Mov10	Moloney leukemia virus 10	0.039
Tmprss15	transmembrane protease, serine 15	0.039
Ear5	eosinophil-associated, ribonuclease A family, member 5	0.039
Ubp1	upstream binding protein 1	0.039
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.039
Prss2	protease, serine, 2	0.039
Erap1	endoplasmic reticulum aminopeptidase 1	0.038
Havcr2	hepatitis A virus cellular receptor 2	0.038
Tle4	transducin-like enhancer of split 4, homolog of Drosophila E(spl)	0.038
Crygb	crystallin, gamma B	0.038
Mecp2	methyl CpG binding protein 2	0.038
Gvin1	GTPase, very large interferon inducible 1	0.038
Zcchc6	zinc finger, CCHC domain containing 6	0.038
Rbl2	retinoblastoma-like 2	0.038
Dntt	deoxynucleotidyltransferase, terminal	0.038
Tcam1	testicular cell adhesion molecule 1	0.038
Muc13	mucin 13, epithelial transmembrane	0.038
Trim15	tripartite motif-containing 15	0.038	Human Mouse
Il1rl2	interleukin 1 receptor-like 2	0.038
Gpr65	G-protein coupled receptor 65	0.037
Slc12a4	solute carrier family 12, member 4	0.037
Fes	feline sarcoma oncogene	0.037
H6pd	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)	0.037
Per3	period homolog 3 (Drosophila)	0.037