IMP: Integrative Multi-species Prediction

Mus musculus

34 genes annotated in mouse

extrinsic apoptotic signaling pathway via death domain receptors

A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with a ligand binding to a death domain receptor on the cell surface, and ends when the execution phase of apoptosis is triggered.

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Known genes in the process in mouseInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "extrinsic apoptotic signaling pathway via death domain receptors"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "extrinsic apoptotic signaling pathway via death domain receptors" (in gray)

Name	Description	Probability	Func Analog Organism
Fas	Fas (TNF receptor superfamily member 6)	0.998
Trp53	transformation related protein 53	0.997
Pten	phosphatase and tensin homolog	0.996
Apc	adenomatosis polyposis coli	0.991
Ptgs2	prostaglandin-endoperoxide synthase 2	0.990
Tgfbr2	transforming growth factor, beta receptor II	0.981	Mouse
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.979
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.975
Igh	immunoglobulin heavy chain complex	0.968
Bcl2	B-cell leukemia/lymphoma 2	0.965	Human Mouse
Ctnnb1	catenin (cadherin associated protein), beta 1	0.960
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.934
Bax	BCL2-associated X protein	0.916
Ccl2	chemokine (C-C motif) ligand 2	0.897
Psen1	presenilin 1	0.893	Mouse
Smad4	MAD homolog 4 (Drosophila)	0.881
Smad3	MAD homolog 3 (Drosophila)	0.852
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.843	Mouse
Tlr4	toll-like receptor 4	0.822
Vhl	von Hippel-Lindau tumor suppressor	0.818
Tnf	tumor necrosis factor	0.817
Cd44	CD44 antigen	0.774
Rxra	retinoid X receptor alpha	0.761
Mmp9	matrix metallopeptidase 9	0.740
Hif1a	hypoxia inducible factor 1, alpha subunit	0.721
Casp8	caspase 8	0.702
Notch2	Notch gene homolog 2 (Drosophila)	0.657
Lyz2	lysozyme 2	0.622
Tgfbr1	transforming growth factor, beta receptor I	0.619	Mouse
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.573
Vegfa	vascular endothelial growth factor A	0.555
Fgfr2	fibroblast growth factor receptor 2	0.546
Lta	lymphotoxin A	0.537	Mouse
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.532
Csf1	colony stimulating factor 1 (macrophage)	0.501
Egfr	epidermal growth factor receptor	0.490
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.488
Fadd	Fas (TNFRSF6)-associated via death domain	0.485
Mcl1	myeloid cell leukemia sequence 1	0.482	Mouse
Kit	kit oncogene	0.454
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.442
Esr1	estrogen receptor 1 (alpha)	0.428
Nos3	nitric oxide synthase 3, endothelial cell	0.428
Notch1	Notch gene homolog 1 (Drosophila)	0.415
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.393
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.387
Ikbkb	inhibitor of kappaB kinase beta	0.358
Nos2	nitric oxide synthase 2, inducible	0.358
Acvr1	activin A receptor, type 1	0.350	Mouse
Sfrp1	secreted frizzled-related protein 1	0.301	Human Mouse
Ncoa3	nuclear receptor coactivator 3	0.298
Sfrp2	secreted frizzled-related protein 2	0.295
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.292
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.277	Mouse
Il10	interleukin 10	0.274
Cd40	CD40 antigen	0.270
Gbp5	guanylate binding protein 5	0.263
Pycard	PYD and CARD domain containing	0.260
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.258
Ikzf1	IKAROS family zinc finger 1	0.243
Il6st	interleukin 6 signal transducer	0.239
Mdm2	transformed mouse 3T3 cell double minute 2	0.239
Chuk	conserved helix-loop-helix ubiquitous kinase	0.226
Casp1	caspase 1	0.225	Mouse
Braf	Braf transforming gene	0.221	Mouse
Runx1	runt related transcription factor 1	0.218
Rb1	retinoblastoma 1	0.218
Adam17	a disintegrin and metallopeptidase domain 17	0.213
Eng	endoglin	0.207
Ifng	interferon gamma	0.204
Vcl	vinculin	0.202
Ret	ret proto-oncogene	0.198
Kitl	kit ligand	0.194
Thbs1	thrombospondin 1	0.169	Human
Sox9	SRY-box containing gene 9	0.169
Cyld	cylindromatosis (turban tumor syndrome)	0.167
Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.166	Human
Lyst	lysosomal trafficking regulator	0.156
Nf1	neurofibromatosis 1	0.154
Casp3	caspase 3	0.147
Rarg	retinoic acid receptor, gamma	0.144
Ltb	lymphotoxin B	0.144
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.141	Human
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.139
Stk4	serine/threonine kinase 4	0.138
Sufu	suppressor of fused homolog (Drosophila)	0.137
Fgg	fibrinogen gamma chain	0.136
Hmgb1	high mobility group box 1	0.133	Mouse
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.132	Mouse
Stat3	signal transducer and activator of transcription 3	0.130
Ptch1	patched homolog 1	0.130
Bak1	BCL2-antagonist/killer 1	0.128	Mouse
Ikbkg	inhibitor of kappaB kinase gamma	0.125
Rara	retinoic acid receptor, alpha	0.121
Stag1	stromal antigen 1	0.119
Pml	promyelocytic leukemia	0.116
Il7	interleukin 7	0.112
Eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2	0.107
Rad21	RAD21 homolog (S. pombe)	0.100
Ece1	endothelin converting enzyme 1	0.099
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.098
Foxc1	forkhead box C1	0.098
Skil	SKI-like	0.097
Mapk3	mitogen-activated protein kinase 3	0.095
Fgfr1	fibroblast growth factor receptor 1	0.095
Dek	DEK oncogene (DNA binding)	0.095
Xiap	X-linked inhibitor of apoptosis	0.094
Il1b	interleukin 1 beta	0.094
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.092
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.090
Traf6	TNF receptor-associated factor 6	0.088
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.086
Wt1	Wilms tumor 1 homolog	0.086
Trp73	transformation related protein 73	0.084
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.084
Ep300	E1A binding protein p300	0.083
Cav1	caveolin 1, caveolae protein	0.083
Selp	selectin, platelet	0.082
Stk3	serine/threonine kinase 3 (Ste20, yeast homolog)	0.082
Irf1	interferon regulatory factor 1	0.081
Hmgn5	high-mobility group nucleosome binding domain 5	0.079
Lif	leukemia inhibitory factor	0.078
Il1r1	interleukin 1 receptor, type I	0.078
Stk11	serine/threonine kinase 11	0.077
Gtf2ird1	general transcription factor II I repeat domain-containing 1	0.075
Hspa1b	heat shock protein 1B	0.075
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.075
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.071
Rbl1	retinoblastoma-like 1 (p107)	0.070
Stxbp5	syntaxin binding protein 5 (tomosyn)	0.069
Aim2	absent in melanoma 2	0.068
Vdr	vitamin D receptor	0.068
Suz12	suppressor of zeste 12 homolog (Drosophila)	0.067
Tgfb1	transforming growth factor, beta 1	0.066
Atr	ataxia telangiectasia and Rad3 related	0.066
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.065
Pik3c2a	phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide	0.065
Il6	interleukin 6	0.064
Nos1	nitric oxide synthase 1, neuronal	0.063
Cxcr5	chemokine (C-X-C motif) receptor 5	0.062
Pvr	poliovirus receptor	0.062
Ahsg	alpha-2-HS-glycoprotein	0.062
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.059
Nucks1	nuclear casein kinase and cyclin-dependent kinase substrate 1	0.059
Ncstn	nicastrin	0.058
Lmna	lamin A	0.058
Il4ra	interleukin 4 receptor, alpha	0.057
Rras	Harvey rat sarcoma oncogene, subgroup R	0.057
Nlrp3	NLR family, pyrin domain containing 3	0.057
Pkd1	polycystic kidney disease 1 homolog	0.056
Ambp	alpha 1 microglobulin/bikunin	0.055
Bbc3	BCL2 binding component 3	0.055
Plg	plasminogen	0.054	Mouse
Tox	thymocyte selection-associated high mobility group box	0.054
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.053
Dbr1	debranching enzyme homolog 1 (S. cerevisiae)	0.053
F2	coagulation factor II	0.052
Ifi203	interferon activated gene 203	0.052
Ptma	prothymosin alpha	0.051
Pnpla6	patatin-like phospholipase domain containing 6	0.051
Serpina10	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.049
Il2rg	interleukin 2 receptor, gamma chain	0.048
Wrn	Werner syndrome homolog (human)	0.048
Zfp36	zinc finger protein 36	0.048
Cpd	carboxypeptidase D	0.048
Gpc3	glypican 3	0.048
Mcm4	minichromosome maintenance deficient 4 homolog (S. cerevisiae)	0.046
Il18	interleukin 18	0.045
Meox2	mesenchyme homeobox 2	0.045
Sumo1	SMT3 suppressor of mif two 3 homolog 1 (yeast)	0.044
Plau	plasminogen activator, urokinase	0.044	Mouse
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.043
Lox	lysyl oxidase	0.043
Cxcl13	chemokine (C-X-C motif) ligand 13	0.043
Cldn2	claudin 2	0.042
Pgr	progesterone receptor	0.042
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.042
Ccr1	chemokine (C-C motif) receptor 1	0.042
Shc1	src homology 2 domain-containing transforming protein C1	0.041
S1pr2	sphingosine-1-phosphate receptor 2	0.041
Arhgef12	Rho guanine nucleotide exchange factor (GEF) 12	0.040
Cxcr4	chemokine (C-X-C motif) receptor 4	0.040
Birc3	baculoviral IAP repeat-containing 3	0.039
Apoe	apolipoprotein E	0.039
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.038
Cd28	CD28 antigen	0.038
Osmr	oncostatin M receptor	0.037
Ch25h	cholesterol 25-hydroxylase	0.037
Atp6v0b	ATPase, H+ transporting, lysosomal V0 subunit B	0.037
Hipk3	homeodomain interacting protein kinase 3	0.036
St3gal2	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	0.036
Cd2ap	CD2-associated protein	0.036
Prrx2	paired related homeobox 2	0.036
Traf2	TNF receptor-associated factor 2	0.035
Apoa4	apolipoprotein A-IV	0.034
Stat6	signal transducer and activator of transcription 6	0.034
Aff1	AF4/FMR2 family, member 1	0.034
Itch	itchy, E3 ubiquitin protein ligase	0.034
Hnf4a	hepatic nuclear factor 4, alpha	0.034
Mgp	matrix Gla protein	0.034
Ctsk	cathepsin K	0.033
Ednrb	endothelin receptor type B	0.033
Fst	follistatin	0.033
Efnb2	ephrin B2	0.032
Pik3cb	phosphatidylinositol 3-kinase, catalytic, beta polypeptide	0.032
Plaur	plasminogen activator, urokinase receptor	0.031
Psenen	presenilin enhancer 2 homolog (C. elegans)	0.031
Dck	deoxycytidine kinase	0.031
Pkn2	protein kinase N2	0.031
Il1a	interleukin 1 alpha	0.030
Ubxn1	UBX domain protein 1	0.030
Prkg1	protein kinase, cGMP-dependent, type I	0.030
Prkcd	protein kinase C, delta	0.030
Fgf7	fibroblast growth factor 7	0.029
Ednra	endothelin receptor type A	0.029
Myc	myelocytomatosis oncogene	0.029
Slfn1	schlafen 1	0.029
Bid	BH3 interacting domain death agonist	0.028
Rnd3	Rho family GTPase 3	0.028
App	amyloid beta (A4) precursor protein	0.028
Anp32e	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E	0.028
Wbp5	WW domain binding protein 5	0.027
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.027
Cfi	complement component factor i	0.027
Nckap1	NCK-associated protein 1	0.027
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.026
Fbn1	fibrillin 1	0.026
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.026
Ahnak	AHNAK nucleoprotein (desmoyokin)	0.026
Spna2	spectrin alpha 2	0.026
Il2rb	interleukin 2 receptor, beta chain	0.026
Cflar	CASP8 and FADD-like apoptosis regulator	0.025	Human
Serpinc1	serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1	0.025
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.025
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.025
Gbp7	guanylate binding protein 7	0.025
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.025
Kng1	kininogen 1	0.025
Vav2	vav 2 oncogene	0.025
Cyp2d10	cytochrome P450, family 2, subfamily d, polypeptide 10	0.025
Ilk	integrin linked kinase	0.025
Bcl2l1	BCL2-like 1	0.025	Mouse
Zap70	zeta-chain (TCR) associated protein kinase	0.025
Met	met proto-oncogene	0.025
Mitf	microphthalmia-associated transcription factor	0.025
Aplp2	amyloid beta (A4) precursor-like protein 2	0.024
Zfp362	zinc finger protein 362	0.024
Itgb3	integrin beta 3	0.024
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.024
Aph1a	anterior pharynx defective 1a homolog (C. elegans)	0.024
Nradd	neurotrophin receptor associated death domain	0.024
Cd14	CD14 antigen	0.024
Cd151	CD151 antigen	0.024
Ywhaq	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.024
Gja1	gap junction protein, alpha 1	0.024
Fzd1	frizzled homolog 1 (Drosophila)	0.024
Gab1	growth factor receptor bound protein 2-associated protein 1	0.024
Cyp1b1	cytochrome P450, family 1, subfamily b, polypeptide 1	0.024
Pbx1	pre B-cell leukemia transcription factor 1	0.024
Thra	thyroid hormone receptor alpha	0.023
Ctnnd1	catenin (cadherin associated protein), delta 1	0.023
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.023	Mouse
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.023
Klf3	Kruppel-like factor 3 (basic)	0.023
Hnrnpk	heterogeneous nuclear ribonucleoprotein K	0.023
Ikzf3	IKAROS family zinc finger 3	0.023
Id2	inhibitor of DNA binding 2	0.023
Hnrnpa1	heterogeneous nuclear ribonucleoprotein A1	0.023
Tmpo	thymopoietin	0.023
Hs2st1	heparan sulfate 2-O-sulfotransferase 1	0.023
Smad7	MAD homolog 7 (Drosophila)	0.022
Bmp4	bone morphogenetic protein 4	0.022
Tgfb2	transforming growth factor, beta 2	0.022
Akr1b8	aldo-keto reductase family 1, member B8	0.022
Ier3	immediate early response 3	0.022
Ces1c	carboxylesterase 1C	0.022
Hook2	hook homolog 2 (Drosophila)	0.022
Mfn2	mitofusin 2	0.022
Gba	glucosidase, beta, acid	0.022
Ptch2	patched homolog 2	0.022
Snrpb2	U2 small nuclear ribonucleoprotein B	0.022
Daxx	Fas death domain-associated protein	0.021
Plxna1	plexin A1	0.021
Htt	huntingtin	0.021
Tlr6	toll-like receptor 6	0.021
Pou2af1	POU domain, class 2, associating factor 1	0.021
Inhba	inhibin beta-A	0.021
Sell	selectin, lymphocyte	0.021
Cst3	cystatin C	0.021
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.021	Mouse
Thbs2	thrombospondin 2	0.021
Morc3	microrchidia 3	0.021
Jag1	jagged 1	0.021
Spp1	secreted phosphoprotein 1	0.021
Raf1	v-raf-leukemia viral oncogene 1	0.021
Ccnd1	cyclin D1	0.021
Psen2	presenilin 2	0.020
Smo	smoothened homolog (Drosophila)	0.020
Kif5b	kinesin family member 5B	0.020
St3gal1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	0.020
Ltbr	lymphotoxin B receptor	0.020
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.020
Mib1	mindbomb homolog 1 (Drosophila)	0.020
2610039C10Rik	RIKEN cDNA 2610039C10 gene	0.020
Apoa1	apolipoprotein A-I	0.020
Hdac7	histone deacetylase 7	0.020
Rock1	Rho-associated coiled-coil containing protein kinase 1	0.020	Mouse
Tgm2	transglutaminase 2, C polypeptide	0.020
Plin2	perilipin 2	0.020
Hnrnpa2b1	heterogeneous nuclear ribonucleoprotein A2/B1	0.020
Anxa1	annexin A1	0.020
Emp1	epithelial membrane protein 1	0.020
C3	complement component 3	0.020
Flot1	flotillin 1	0.020
Ifngr1	interferon gamma receptor 1	0.019
Epas1	endothelial PAS domain protein 1	0.019
Plscr1	phospholipid scramblase 1	0.019
Sfpi1	SFFV proviral integration 1	0.019
Diablo	diablo homolog (Drosophila)	0.019
Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.019
Gdf15	growth differentiation factor 15	0.019
Clic1	chloride intracellular channel 1	0.019
Mkl2	MKL/myocardin-like 2	0.019
Klf6	Kruppel-like factor 6	0.019
Samm50	sorting and assembly machinery component 50 homolog (S. cerevisiae)	0.019
Gata4	GATA binding protein 4	0.019
Aqp8	aquaporin 8	0.019
Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.019
Prss30	protease, serine, 30	0.019
Smc4	structural maintenance of chromosomes 4	0.019
Ect2	ect2 oncogene	0.019
Card11	caspase recruitment domain family, member 11	0.019
Arhgef2	rho/rac guanine nucleotide exchange factor (GEF) 2	0.019
Sema3c	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	0.019
Gdnf	glial cell line derived neurotrophic factor	0.019
Kif3a	kinesin family member 3A	0.019
Cxcl2	chemokine (C-X-C motif) ligand 2	0.018
Shoc2	soc-2 (suppressor of clear) homolog (C. elegans)	0.018
Gsn	gelsolin	0.018
Tor3a	torsin family 3, member A	0.018
Map3k5	mitogen-activated protein kinase kinase kinase 5	0.018
Itk	IL2-inducible T-cell kinase	0.018
Atp8a1	ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1	0.018
Jup	junction plakoglobin	0.018
Cbl	Casitas B-lineage lymphoma	0.018
Prr13	proline rich 13	0.018
Qsox1	quiescin Q6 sulfhydryl oxidase 1	0.018
Fmn1	formin 1	0.018
Cstb	cystatin B	0.018
Icos	inducible T-cell co-stimulator	0.018
Ptges	prostaglandin E synthase	0.018
Gc	group specific component	0.018
Ceacam1	carcinoembryonic antigen-related cell adhesion molecule 1	0.018
Il18rap	interleukin 18 receptor accessory protein	0.017
Tax1bp1	Tax1 (human T-cell leukemia virus type I) binding protein 1	0.017
H3f3b	H3 histone, family 3B	0.017
Bcl2a1a	B-cell leukemia/lymphoma 2 related protein A1a	0.017	Mouse
Apof	apolipoprotein F	0.017
Ripk3	receptor-interacting serine-threonine kinase 3	0.017
Itgal	integrin alpha L	0.017
Serpinf2	serine (or cysteine) peptidase inhibitor, clade F, member 2	0.017
Rod1	ROD1 regulator of differentiation 1 (S. pombe)	0.017
Rel	reticuloendotheliosis oncogene	0.017
Gm7592	predicted gene 7592	0.017
Tgfbr3	transforming growth factor, beta receptor III	0.017
Yap1	yes-associated protein 1	0.017
Kif1b	kinesin family member 1B	0.017
Socs1	suppressor of cytokine signaling 1	0.017
Cnot6	CCR4-NOT transcription complex, subunit 6	0.017
Pygb	brain glycogen phosphorylase	0.017
Gimap1	GTPase, IMAP family member 1	0.017
Nt5e	5' nucleotidase, ecto	0.017
Il1rl1	interleukin 1 receptor-like 1	0.017
Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.017
Mrpl13	mitochondrial ribosomal protein L13	0.017
Aicda	activation-induced cytidine deaminase	0.017
Mvp	major vault protein	0.017
Lsm5	LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.017
Sele	selectin, endothelial cell	0.017
Arhgap5	Rho GTPase activating protein 5	0.017
Apom	apolipoprotein M	0.017
Itgav	integrin alpha V	0.017
Nodal	nodal	0.017
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.017
Tnfrsf11b	tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)	0.016
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.016
Plac8	placenta-specific 8	0.016
Creb1	cAMP responsive element binding protein 1	0.016
Plagl1	pleiomorphic adenoma gene-like 1	0.016
Arid5a	AT rich interactive domain 5A (MRF1-like)	0.016
Mat1a	methionine adenosyltransferase I, alpha	0.016
Bcl3	B-cell leukemia/lymphoma 3	0.016
Gna11	guanine nucleotide binding protein, alpha 11	0.016
Gna13	guanine nucleotide binding protein, alpha 13	0.016
Mpp5	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)	0.016
Spred1	sprouty protein with EVH-1 domain 1, related sequence	0.016
Sp3	trans-acting transcription factor 3	0.016
F12	coagulation factor XII (Hageman factor)	0.016	Mouse
Tbx6	T-box 6	0.016
Cyp2d26	cytochrome P450, family 2, subfamily d, polypeptide 26	0.016
Casp7	caspase 7	0.016	Mouse
Cd80	CD80 antigen	0.016
Mocs1	molybdenum cofactor synthesis 1	0.015
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.015
S100a6	S100 calcium binding protein A6 (calcyclin)	0.015
Nod2	nucleotide-binding oligomerization domain containing 2	0.015
Bex1	brain expressed gene 1	0.015
Vcam1	vascular cell adhesion molecule 1	0.015
Cd38	CD38 antigen	0.015
Hnrpdl	heterogeneous nuclear ribonucleoprotein D-like	0.015
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.015
Fgf8	fibroblast growth factor 8	0.015
Gkn1	gastrokine 1	0.015
Krt4	keratin 4	0.015
Lama5	laminin, alpha 5	0.015
Lbr	lamin B receptor	0.015
Rbm3	RNA binding motif protein 3	0.015
Lepr	leptin receptor	0.015
Hspb8	heat shock protein 8	0.015
Ceacam2	carcinoembryonic antigen-related cell adhesion molecule 2	0.015
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.015
Dlg1	discs, large homolog 1 (Drosophila)	0.015
Lck	lymphocyte protein tyrosine kinase	0.015
Atp2b1	ATPase, Ca++ transporting, plasma membrane 1	0.014
BC147527	cDNA sequence BC147527	0.014
Hoxa3	homeobox A3	0.014
Lfng	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	0.014
Gem	GTP binding protein (gene overexpressed in skeletal muscle)	0.014
Zcchc14	zinc finger, CCHC domain containing 14	0.014
Pim1	proviral integration site 1	0.014
Mmp13	matrix metallopeptidase 13	0.014
Ehd3	EH-domain containing 3	0.014
Ar	androgen receptor	0.014
Cbx3	chromobox homolog 3 (Drosophila HP1 gamma)	0.014
Galnt4	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4	0.014
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.014
Rab17	RAB17, member RAS oncogene family	0.014
Mid2	midline 2	0.014
Zbtb7b	zinc finger and BTB domain containing 7B	0.014
Hmox1	heme oxygenase (decycling) 1	0.014	Human
Kif3b	kinesin family member 3B	0.014
Dnase1l1	deoxyribonuclease 1-like 1	0.014
Cdk14	cyclin-dependent kinase 14	0.014
C4bp	complement component 4 binding protein	0.014
H2-T24	histocompatibility 2, T region locus 24	0.014
Prkci	protein kinase C, iota	0.014
Grlf1	glucocorticoid receptor DNA binding factor 1	0.013
Anxa4	annexin A4	0.013
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.013
Hpx	hemopexin	0.013
Tax1bp3	Tax1 (human T-cell leukemia virus type I) binding protein 3	0.013
Ly75	lymphocyte antigen 75	0.013
Rdh10	retinol dehydrogenase 10 (all-trans)	0.013
Ptp4a2	protein tyrosine phosphatase 4a2	0.013
Hip1	huntingtin interacting protein 1	0.013
Cdh5	cadherin 5	0.013
Apaf1	apoptotic peptidase activating factor 1	0.013
Mbp	myelin basic protein	0.013
Aqp9	aquaporin 9	0.013
Twsg1	twisted gastrulation homolog 1 (Drosophila)	0.013
Nupr1	nuclear protein 1	0.013
Tcf3	transcription factor 3	0.013
Aff4	AF4/FMR2 family, member 4	0.013
Plcb3	phospholipase C, beta 3	0.013
Usp12	ubiquitin specific peptidase 12	0.013
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.013
Procr	protein C receptor, endothelial	0.013
Fosl1	fos-like antigen 1	0.013
Plat	plasminogen activator, tissue	0.013	Mouse
Fosl2	fos-like antigen 2	0.013
Gcnt2	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme	0.013
Gimap4	GTPase, IMAP family member 4	0.013
Adora2a	adenosine A2a receptor	0.013
Bcl6	B-cell leukemia/lymphoma 6	0.013
Atp11c	ATPase, class VI, type 11C	0.013
Fshr	follicle stimulating hormone receptor	0.013
Capns1	calpain, small subunit 1	0.013
Pign	phosphatidylinositol glycan anchor biosynthesis, class N	0.013
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.013
Ergic3	ERGIC and golgi 3	0.013
Slfn4	schlafen 4	0.013
Pld3	phospholipase D family, member 3	0.013
Apob	apolipoprotein B	0.013
Ifnar1	interferon (alpha and beta) receptor 1	0.013
Enah	enabled homolog (Drosophila)	0.013
Bptf	bromodomain PHD finger transcription factor	0.013
Terf1	telomeric repeat binding factor 1	0.013
Ptk2	PTK2 protein tyrosine kinase 2	0.012
Smad2	MAD homolog 2 (Drosophila)	0.012
C5ar1	complement component 5a receptor 1	0.012
Galc	galactosylceramidase	0.012
Mtch1	mitochondrial carrier homolog 1 (C. elegans)	0.012
Lats2	large tumor suppressor 2	0.012
Rc3h1	RING CCCH (C3H) domains 1	0.012
Fgl2	fibrinogen-like protein 2	0.012
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.012
Lrrc40	leucine rich repeat containing 40	0.012
Fam50a	family with sequence similarity 50, member A	0.012
Car5a	carbonic anhydrase 5a, mitochondrial	0.012
Angpt1	angiopoietin 1	0.012
Rabac1	Rab acceptor 1 (prenylated)	0.012
Cpn1	carboxypeptidase N, polypeptide 1	0.012
Cxcl5	chemokine (C-X-C motif) ligand 5	0.012
Slfn2	schlafen 2	0.012
S100a4	S100 calcium binding protein A4	0.012
Crtam	cytotoxic and regulatory T cell molecule	0.012
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.012
Itga8	integrin alpha 8	0.012
Apobec1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	0.012
Igfals	insulin-like growth factor binding protein, acid labile subunit	0.012
Ccl7	chemokine (C-C motif) ligand 7	0.012
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.012
Zfp26	zinc finger protein 26	0.012
Sgpl1	sphingosine phosphate lyase 1	0.012
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.012
Ctsb	cathepsin B	0.012
Spnb2	spectrin beta 2	0.012
S100a3	S100 calcium binding protein A3	0.012
Fxyd5	FXYD domain-containing ion transport regulator 5	0.012
Cd40lg	CD40 ligand	0.012	Mouse
Nphs2	nephrosis 2 homolog, podocin (human)	0.012
Ewsr1	Ewing sarcoma breakpoint region 1	0.012
Slc40a1	solute carrier family 40 (iron-regulated transporter), member 1	0.012
Il22	interleukin 22	0.012
Errfi1	ERBB receptor feedback inhibitor 1	0.012
Slc6a12	solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12	0.012
Adam8	a disintegrin and metallopeptidase domain 8	0.012
Klrc1	killer cell lectin-like receptor subfamily C, member 1	0.011
Cd160	CD160 antigen	0.011
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.011
Amdhd1	amidohydrolase domain containing 1	0.011
Ahr	aryl-hydrocarbon receptor	0.011
Coq7	demethyl-Q 7	0.011
Trak2	trafficking protein, kinesin binding 2	0.011
Itga5	integrin alpha 5 (fibronectin receptor alpha)	0.011
Timp1	tissue inhibitor of metalloproteinase 1	0.011
Sh2d2a	SH2 domain protein 2A	0.011
Itm2c	integral membrane protein 2C	0.011
Irak3	interleukin-1 receptor-associated kinase 3	0.011
Nagk	N-acetylglucosamine kinase	0.011
Pklr	pyruvate kinase liver and red blood cell	0.011
Atm	ataxia telangiectasia mutated homolog (human)	0.011
Haus7	HAUS augmin-like complex, subunit 7	0.011
Lcor	ligand dependent nuclear receptor corepressor	0.011
AW555464	expressed sequence AW555464	0.011
Frk	fyn-related kinase	0.011
Apoc4	apolipoprotein C-IV	0.011
Capg	capping protein (actin filament), gelsolin-like	0.011
Oc90	otoconin 90	0.011
Tnfsf9	tumor necrosis factor (ligand) superfamily, member 9	0.011
Mtor	mechanistic target of rapamycin (serine/threonine kinase)	0.011
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.011
Gp9	glycoprotein 9 (platelet)	0.011
Slc26a1	solute carrier family 26 (sulfate transporter), member 1	0.011
Mmp3	matrix metallopeptidase 3	0.011
Ptrh1	peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)	0.011
Slbp	stem-loop binding protein	0.011
Pkd2	polycystic kidney disease 2	0.011
Ftl1	ferritin light chain 1	0.011
Camk1	calcium/calmodulin-dependent protein kinase I	0.011
Inhbb	inhibin beta-B	0.011
Itih1	inter-alpha trypsin inhibitor, heavy chain 1	0.011
Apoh	apolipoprotein H	0.011
Mov10	Moloney leukemia virus 10	0.011
Pdcd1	programmed cell death 1	0.011
Agxt	alanine-glyoxylate aminotransferase	0.011
Deaf1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.011
Il1rn	interleukin 1 receptor antagonist	0.011
Fut4	fucosyltransferase 4	0.011
Nmi	N-myc (and STAT) interactor	0.011
Avpr1a	arginine vasopressin receptor 1A	0.011
Ufc1	ubiquitin-fold modifier conjugating enzyme 1	0.011
Tcrd	T-cell receptor delta chain	0.011
Col4a3	collagen, type IV, alpha 3	0.011
Col1a1	collagen, type I, alpha 1	0.011
Ccrl2	chemokine (C-C motif) receptor-like 2	0.011
Ldlr	low density lipoprotein receptor	0.011
Pbrm1	polybromo 1	0.011
Kiss1	KiSS-1 metastasis-suppressor	0.011
Crct1	cysteine-rich C-terminal 1	0.011
Gadd45a	growth arrest and DNA-damage-inducible 45 alpha	0.011
Edn1	endothelin 1	0.011
Abcc5	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	0.011
Serpina6	serine (or cysteine) peptidase inhibitor, clade A, member 6	0.011
Gsk3b	glycogen synthase kinase 3 beta	0.011
Fgfr3	fibroblast growth factor receptor 3	0.011
Aph1b	anterior pharynx defective 1b homolog (C. elegans)	0.011
Kif13a	kinesin family member 13A	0.011
Slc25a47	solute carrier family 25, member 47	0.011
Trp63	transformation related protein 63	0.011
Anxa2	annexin A2	0.011
Dll1	delta-like 1 (Drosophila)	0.011
Ppig	peptidyl-prolyl isomerase G (cyclophilin G)	0.011
Nkx2-1	NK2 homeobox 1	0.011
Ptx3	pentraxin related gene	0.011
Sav1	salvador homolog 1 (Drosophila)	0.011
Clstn1	calsyntenin 1	0.010
Nedd9	neural precursor cell expressed, developmentally down-regulated gene 9	0.010
Spin1	spindlin 1	0.010
Suv420h2	suppressor of variegation 4-20 homolog 2 (Drosophila)	0.010
C8b	complement component 8, beta polypeptide	0.010
Upp1	uridine phosphorylase 1	0.010
Ptprg	protein tyrosine phosphatase, receptor type, G	0.010
Hist1h1c	histone cluster 1, H1c	0.010
Itgb5	integrin beta 5	0.010
Iqgap1	IQ motif containing GTPase activating protein 1	0.010
Ifnb1	interferon beta 1, fibroblast	0.010
Il3ra	interleukin 3 receptor, alpha chain	0.010
Myd88	myeloid differentiation primary response gene 88	0.010
Cd70	CD70 antigen	0.010
Ptgs1	prostaglandin-endoperoxide synthase 1	0.010
Gdf2	growth differentiation factor 2	0.010
Slfn3	schlafen 3	0.010
Ppard	peroxisome proliferator activator receptor delta	0.010
Fgfrl1	fibroblast growth factor receptor-like 1	0.010
Pla2g4a	phospholipase A2, group IVA (cytosolic, calcium-dependent)	0.010
Camk2d	calcium/calmodulin-dependent protein kinase II, delta	0.010
Lmnb1	lamin B1	0.010
Pcdh18	protocadherin 18	0.010
Gnai3	guanine nucleotide binding protein (G protein), alpha inhibiting 3	0.010
Ids	iduronate 2-sulfatase	0.010
Pdpn	podoplanin	0.010
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.010
Aggf1	angiogenic factor with G patch and FHA domains 1	0.010
Ggta1	glycoprotein galactosyltransferase alpha 1, 3	0.010
Snai3	snail homolog 3 (Drosophila)	0.010
Rrad	Ras-related associated with diabetes	0.010
Kcnj15	potassium inwardly-rectifying channel, subfamily J, member 15	0.010
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.010
Serpinb9b	serine (or cysteine) peptidase inhibitor, clade B, member 9b	0.010
Ddr2	discoidin domain receptor family, member 2	0.010
Npr3	natriuretic peptide receptor 3	0.010
Gdf5	growth differentiation factor 5	0.010
Fnbp1l	formin binding protein 1-like	0.010
Ctsd	cathepsin D	0.010
Osbpl5	oxysterol binding protein-like 5	0.010
Ppp2r5b	protein phosphatase 2, regulatory subunit B (B56), beta isoform	0.010
Guca2a	guanylate cyclase activator 2a (guanylin)	0.010
Ptprj	protein tyrosine phosphatase, receptor type, J	0.010
Jak3	Janus kinase 3	0.010
Xpa	xeroderma pigmentosum, complementation group A	0.010
Fus	fusion, derived from t(12;16) malignant liposarcoma (human)	0.010